cp 96345 has been researched along with Disease Models, Animal in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (50.00) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Hisaoka-Nakashima, K; Morioka, N; Nakamura, Y; Nakata, Y; Zhang, FF | 1 |
| Cox, RA; Deyo, DJ; Hawkins, HK; Herndon, DN; Jacob, RK; Jacob, S; Traber, DL | 1 |
| Boudah, A; Jasmin, L; Ohara, PT | 1 |
| Bhatia, M; Sun, J | 1 |
| Cahill, CM; Henry, JL; Landau, AM; Ribeiro-da-Silva, A; St Louis, M; Yashpal, K | 1 |
| Bordner, J; Bryce, DK; Drozda, SE; Jackson, ER; Longo, KP; Lowe, JA; McLean, S; Morrone, J; Snider, RM; Zorn, SH | 1 |
| Sluka, KA; Westlund, KN | 1 |
| Doerfler, DL; Sailstad, DM; Selgrade, M; Veronesi, B | 1 |
| Holmes, MD; Reynolds, AM; Reynolds, PN; Rice, AJ; Scicchitano, R; Thornton, AT | 1 |
| Austin-Ritchie, T; Baker, S; Carraway, RE; Hollins, C; Luber-Narod, J; Malhotra, RK; Menon, M | 1 |
| Fan, DS; Liu, T; Yang, PC; Zhang, TY | 1 |
| Ho, CY; Kou, YR; Lin, YS; Tang, GJ | 1 |
| Asai, R; Kanai, Y; Murase, A; Nagahisa, A; Nakagaki, T; Shieh, TC; Taniguchi, K; Tsuchiya-Nakagaki, M | 1 |
1 review(s) available for cp 96345 and Disease Models, Animal
| Article | Year |
|---|---|
Discovery of CP-96,345 and its characterization in disease models involving substance P.
Topics: Analgesics; Animals; Asthma; Binding, Competitive; Biphenyl Compounds; Disease Models, Animal; Inflammation; Pain; Receptors, Neurokinin-2; Substance P | 1993 |
13 other study(ies) available for cp 96345 and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Downregulation of connexin36 in mouse spinal dorsal horn neurons leads to mechanical allodynia.
Topics: Analysis of Variance; Animals; Biphenyl Compounds; Connexins; Disease Models, Animal; Dizocilpine Maleate; Down-Regulation; Gap Junction delta-2 Protein; Glutamate Decarboxylase; Glycine Plasma Membrane Transport Proteins; Hyperalgesia; Interneurons; Male; Mice; Neuroprotective Agents; Pain Threshold; Posterior Horn Cells; RNA, Small Interfering; Sciatic Neuropathy | 2015 |
Substance P antagonist CP-96345 blocks lung vascular leakage and inflammation more effectively than its stereoisomer CP-96344 in a mouse model of smoke inhalation and burn injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Disease Models, Animal; Mice; Smoke; Stereoisomerism; Substance P | 2010 |
Long-term effects of decreased noradrenergic central nervous system innervation on pain behavior and opioid antinociception.
Topics: Analgesics, Opioid; Animals; Antibodies, Monoclonal; Behavior, Animal; Biphenyl Compounds; Central Nervous System; Denervation; Disease Models, Animal; Disease Progression; Female; Hyperalgesia; Immunohistochemistry; Immunotoxins; Injections, Intraventricular; Injections, Spinal; Lumbosacral Region; Male; Morphine; Norepinephrine; Pain; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Ribosome Inactivating Proteins, Type 1; Saporins; Spinal Cord; Substance P; Time | 2003 |
Blockade of neurokinin-1 receptor attenuates CC and CXC chemokine production in experimental acute pancreatitis and associated lung injury.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Ceruletide; Chemokine CCL2; Chemokine CCL3; Chemokine CCL4; Chemokine CXCL2; Chemokines; Disease Models, Animal; Gene Expression Regulation; Lung; Lung Injury; Macrophage Inflammatory Proteins; Macrophages, Alveolar; Male; Mice; Neurokinin-1 Receptor Antagonists; Pancreatitis; Reverse Transcriptase Polymerase Chain Reaction; RNA; Transcription, Genetic | 2007 |
Sensory neuron and substance P involvement in symptoms of a zymosan-induced rat model of acute bowel inflammation.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Colitis; Colon; Disease Models, Animal; Enteric Nervous System; Ethanol; Inflammation Mediators; Male; Neurogenic Inflammation; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Oligonucleotides, Antisense; Pain; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; RNA, Messenger; Substance P; Sympathetic Nervous System; Zymosan | 2007 |
Spinal cord amino acid release and content in an arthritis model: the effects of pretreatment with non-NMDA, NMDA, and NK1 receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Arthritis; Biphenyl Compounds; Disease Models, Animal; Glutamates; Glutamic Acid; Immunohistochemistry; Lidocaine; Male; Microdialysis; Neurokinin-1 Receptor Antagonists; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1993 |
Neuropeptide modulation of chemically induced skin irritation.
Topics: Administration, Cutaneous; Animals; Benzamides; Biphenyl Compounds; Capsaicin; Dermatitis, Contact; Dinitrofluorobenzene; Disease Models, Animal; Dose-Response Relationship, Drug; Ear, External; Female; Irritants; Mice; Mice, Inbred BALB C; Neurokinin A; Neuropeptides; Piperidines; Skin; Substance P; Synaptic Transmission | 1995 |
Tachykinins contribute to the acute airways response to allergen in sheep actively sensitized to Ascaris suum.
Topics: Allergens; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ascaris suum; Asthma; Biphenyl Compounds; Bronchial Hyperreactivity; Bronchoconstriction; Capsaicin; Disease Models, Animal; Drug Interactions; Glycopeptides; Immunization; Reference Values; Reproducibility of Results; Sheep; Tachykinins | 1997 |
Role of substance P in several models of bladder inflammation.
Topics: Animals; Biphenyl Compounds; Cystitis; Disease Models, Animal; Female; Immunohistochemistry; Lipopolysaccharides; Neurokinin-1 Receptor Antagonists; Poly I-C; Rats; Substance P; Urinary Bladder; Urination; Xylenes | 1997 |
Effect of substance P on the short-circuit current of rat nasal mucosal epithelium.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Disease Models, Animal; Electric Stimulation; Epithelium; Histamine H1 Antagonists; Histamine H2 Antagonists; Histamine Release; Male; Mast Cells; Nasal Mucosa; Pyrilamine; Ranitidine; Rats; Rats, Sprague-Dawley; Rhinitis, Allergic, Seasonal; Substance P | 1998 |
Alleviation of wood smoke-induced lung injury by tachykinin receptor antagonist and hydroxyl radical scavenger in guinea pigs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Disease Models, Animal; Free Radical Scavengers; Guinea Pigs; Hydroxyl Radical; Male; Neprilysin; Receptors, Tachykinin; Respiratory Distress Syndrome; Tachykinins; Thiourea; Wood | 2001 |
Non-specific activity of (+/-)-CP-96,345 in models of pain and inflammation.
Topics: Analysis of Variance; Animals; Binding Sites; Biphenyl Compounds; Disease Models, Animal; Edema; Inflammation; Male; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Stereoisomerism | 1992 |