Compounds > cp-166,572
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cp-166,572 and Alloxan Diabetes

cp-166,572 has been researched along with Alloxan Diabetes in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Beebe, DA; Brackett, NS; Coutcher, JB; Dina, MS; Mylari, BL; Oates, PJ; Zembrowski, WJ1
Ballinger, WE; Beebe, DA; Berger, R; Chu-Moyer, MY; Coutcher, JB; Day, WW; Li, J; Mylari, BL; Oates, PJ; Weekly, RM1
Blessing, K; Inoue, J; Kador, PF1
Basso, M; Cameron, NE; Cotter, MA; Hohman, TC1
Blessing, K; Greentree, W; Inoue, J; Kador, PF; Lackner, PA; Lizak, MJ; Mori, K; Rodriguez, L; Sato, S; Secchi, EF1

Other Studies

5 other study(ies) available for cp-166,572 and Alloxan Diabetes

ArticleYear
Sorbitol dehydrogenase inhibitors (SDIs): a new potent, enantiomeric SDI, 4-[2-1R-hydroxy-ethyl)-pyrimidin-4-yl]piperazine-1-sulfonic acid dimethylamide.
    Journal of medicinal chemistry, 2001, Aug-16, Volume: 44, Issue:17

    Topics: Administration, Oral; Animals; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fructose; Humans; L-Iditol 2-Dehydrogenase; Pyrimidines; Rats; Sciatic Nerve; Stereoisomerism; Sulfonamides; Tissue Distribution

2001
Orally-effective, long-acting sorbitol dehydrogenase inhibitors: synthesis, structure-activity relationships, and in vivo evaluations of novel heterocycle-substituted piperazino-pyrimidines.
    Journal of medicinal chemistry, 2002, Jan-17, Volume: 45, Issue:2

    Topics: Animals; Chronic Disease; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fructose; L-Iditol 2-Dehydrogenase; Male; Piperazines; Pyrimidines; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Stereoisomerism; Structure-Activity Relationship

2002
Anticataract activity of analogs of a sorbitol dehydrogenase inhibitor.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2004, Volume: 20, Issue:4

    Topics: Animals; Cataract; Diabetes Mellitus, Experimental; Enzyme Inhibitors; L-Iditol 2-Dehydrogenase; Piperazines; Pyrimidines; Rats; Rats, Sprague-Dawley

2004
Comparison of the effects of inhibitors of aldose reductase and sorbitol dehydrogenase on neurovascular function, nerve conduction and tissue polyol pathway metabolites in streptozotocin-diabetic rats.
    Diabetologia, 1997, Volume: 40, Issue:3

    Topics: Aldehyde Reductase; Analysis of Variance; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fructose; Glucose; Inositol; L-Iditol 2-Dehydrogenase; Male; Neural Conduction; Organ Specificity; Peripheral Nerves; Piperazines; Pyrimidines; Rats; Rats, Sprague-Dawley; Sorbitol

1997
Effect of sorbitol dehydrogenase inhibition on sugar cataract formation in galactose-fed and diabetic rats.
    Experimental eye research, 1998, Volume: 67, Issue:2

    Topics: Aldehyde Reductase; Animals; Cataract; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fluorenes; Galactose; Hydantoins; L-Iditol 2-Dehydrogenase; Phthalazines; Piperazines; Pyrimidines; Rats; Rats, Sprague-Dawley

1998