Page last updated: 2024-09-04

cox 189 and Arthritis, Degenerative

cox 189 has been researched along with Arthritis, Degenerative in 26 studies

Research

Studies (26)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	23 (88.46)	29.6817
2010's	3 (11.54)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Krammer, G; Lheritier, K; Littlejohn, TW; MacDonald, TM; Rebuli, R; Reginster, JY; Richard, D	1
Krammer, G; Stricker, K; Yu, S	1
Krammer, G; Lheritier, K; MacDonald, TM; Richard, D	1
Ghiculescu, RA; Lampe, G; Macdonald, GA; Pillans, PI; Wilson, R; Wong, R	1
Macdonald, TM; Mackenzie, IS; Wei, L	1
Ehrsam, E; Farkouh, M; Gitton, X; Hawkey, CJ; Huels, J; Richardson, P	1
Cousin, M; Fiedorowicz-Fabrycy, IF; Gitton, X; Hawkey, CC; Hoexter, G; Nasonov, EL; Pikhlak, EG; Svoboda, P	1
Curran, MP; Lyseng-Williamson, KA	1
Summerton, N	1
Gitton, X; Jayawardene, S; Schnitzer, TJ; Sloan, VS	1
Bannwarth, B; Berenbaum, F	2
Hochberg, MC	1
Ehrsam, E; Garaud, JJ; Gitton, X; Hoexter, G; Krammer, G; Matchaba, P; Mellein, B; Olson, M; Orloff, J; Sloan, VS	1
Goldstein, JL; Rosenberg, JA	1
Choi, L; Mangold, JB; Marshall, P; Rordorf, CM	1
Gitton, X; Hawkey, CJ; Hoexter, G; Richard, D; Weinstein, WM	1
Dougados, M; Gitton, X; Moore, A; Yu, S	1
Abramson, SB; Chesebro, JH; Farkouh, ME; Fuster, V; Greenberg, JD; Hochman, JS; Jeger, RV; Kirshner, H; Lay, CL; Matchaba, PT; Mellein, B; Ramanathan, K; Ruland, S; Verheugt, FW	1
Gitton, X; Hawkey, CJ; Krammer, G; Matchaba, P; Mellein, B; Richard, D; Sallstig, P; Smalley, W; Stricker, K; Weinstein, WM	1
Baraf, HS	1
Burton, B	1
Klotz, U; Shi, S	1
Fleischmann, R; Notter, M; Patel, NP; Reginster, JY; Sallstig, P; Tannenbaum, H	1

Reviews

10 review(s) available for cox 189 and Arthritis, Degenerative

Article	Year
Cardiovascular safety of lumiracoxib: a meta-analysis of randomised controlled trials in patients with osteoarthritis. European journal of clinical pharmacology, 2013, Volume: 69, Issue:2 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Cardiovascular System; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; Humans; Male; Middle Aged; Osteoarthritis	2013
Clinical pharmacology of lumiracoxib, a second-generation cyclooxygenase 2 selective inhibitor. Expert opinion on investigational drugs, 2005, Volume: 14, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cyclooxygenase 2 Inhibitors; Diclofenac; Dysmenorrhea; Female; Gastrointestinal Hemorrhage; Humans; Osteoarthritis; Pain, Postoperative; Randomized Controlled Trials as Topic	2005
COX-2 selective inhibitors in the treatment of arthritis: a rheumatologist perspective. Current topics in medicinal chemistry, 2005, Volume: 5, Issue:5 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Celecoxib; Cost-Benefit Analysis; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Etoricoxib; Humans; Isoxazoles; Lactones; Membrane Proteins; Organic Chemicals; Osteoarthritis; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Pyridines; Randomized Controlled Trials as Topic; Rheumatology; Sulfonamides; Sulfones; Treatment Outcome	2005
Cardiovascular safety of lumiracoxib: a meta-analysis of all randomized controlled trials > or =1 week and up to 1 year in duration of patients with osteoarthritis and rheumatoid arthritis. Clinical therapeutics, 2005, Volume: 27, Issue:8 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cardiovascular Diseases; Cyclooxygenase 2 Inhibitors; Databases, Factual; Diclofenac; Female; Humans; Male; Middle Aged; Organic Chemicals; Osteoarthritis; Randomized Controlled Trials as Topic	2005
Clinical pharmacology of lumiracoxib: a selective cyclo-oxygenase-2 inhibitor. Clinical pharmacokinetics, 2005, Volume: 44, Issue:12 Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Cyclooxygenase 2 Inhibitors; Diclofenac; Humans; Kidney Diseases; Liver Diseases; Organic Chemicals; Osteoarthritis	2005
Gastrointestinal tolerability of lumiracoxib in patients with osteoarthritis and rheumatoid arthritis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2006, Volume: 4, Issue:1 Topics: Aged; Arthritis, Rheumatoid; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Organic Chemicals; Osteoarthritis; Randomized Controlled Trials as Topic	2006
Evaluation of the patient acceptable symptom state in a pooled analysis of two multicentre, randomised, double-blind, placebo-controlled studies evaluating lumiracoxib and celecoxib in patients with osteoarthritis. Arthritis research & therapy, 2007, Volume: 9, Issue:1 Topics: Aged; Celecoxib; Diclofenac; Double-Blind Method; Female; Humans; Male; Middle Aged; Osteoarthritis; Pain Measurement; Patient Satisfaction; Pyrazoles; Sulfonamides	2007
Lumiracoxib in the management of osteoarthritis and acute pain. Expert opinion on pharmacotherapy, 2007, Volume: 8, Issue:10 Topics: Acute Disease; Animals; Cardiovascular Diseases; Cyclooxygenase 2 Inhibitors; Diclofenac; Drug Approval; Humans; Osteoarthritis; Pain; Peptic Ulcer; Risk Assessment; Treatment Outcome	2007
Efficacy of the newest COX-2 selective inhibitors in rheumatic disease. Current pharmaceutical design, 2007, Volume: 13, Issue:22 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Arthritis, Rheumatoid; Cardiovascular Diseases; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Gastrointestinal Hemorrhage; Humans; Membrane Proteins; Osteoarthritis; Patient Selection; Pyridines; Rheumatic Diseases; Risk Assessment; Risk Factors; Spondylitis, Ankylosing; Sulfones	2007
Clinical use and pharmacological properties of selective COX-2 inhibitors. European journal of clinical pharmacology, 2008, Volume: 64, Issue:3 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Drug Monitoring; Etoricoxib; Humans; Osteoarthritis; Pain; Pyrazoles; Pyridines; Sulfonamides; Sulfones	2008

Trials

12 trial(s) available for cox 189 and Arthritis, Degenerative

Article	Year
Effect on blood pressure of lumiracoxib versus ibuprofen in patients with osteoarthritis and controlled hypertension: a randomized trial. Journal of hypertension, 2008, Volume: 26, Issue:8 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cyclooxygenase 2 Inhibitors; Diclofenac; Humans; Hypertension; Ibuprofen; Middle Aged; Osteoarthritis; Treatment Outcome	2008
A 6-week, multicentre, randomised, double-blind, double-dummy, active-controlled, clinical safety study of lumiracoxib and rofecoxib in osteoarthritis patients. BMC musculoskeletal disorders, 2008, Sep-08, Volume: 9 Topics: Aged; Arthralgia; Blood Pressure; Cyclooxygenase 2 Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Edema; Europe; Female; Gastrointestinal Tract; Humans; Incidence; Kidney; Lactones; Longitudinal Studies; Male; Middle Aged; Osteoarthritis; Sulfones	2008
The effects of lumiracoxib 100 mg once daily vs. ibuprofen 600 mg three times daily on the blood pressure profiles of hypertensive osteoarthritis patients taking different classes of antihypertensive agents. International journal of clinical practice, 2010, Volume: 64, Issue:6 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypertension; Ibuprofen; Male; Middle Aged; Osteoarthritis; Treatment Outcome	2010
Cardiovascular safety of lumiracoxib: a meta-analysis of randomised controlled trials in patients with osteoarthritis. European journal of clinical pharmacology, 2013, Volume: 69, Issue:2 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Cardiovascular System; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; Humans; Male; Middle Aged; Osteoarthritis	2013
Therapeutic arthritis research and gastrointestinal event trial of lumiracoxib - study design and patient demographics. Alimentary pharmacology & therapeutics, 2004, Jul-01, Volume: 20, Issue:1 Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Health Status; Humans; Ibuprofen; Isoenzymes; Membrane Proteins; Middle Aged; Naproxen; Organic Chemicals; Osteoarthritis; Peptic Ulcer; Prognosis; Prostaglandin-Endoperoxide Synthases; Risk Factors	2004
Gastroduodenal safety and tolerability of lumiracoxib compared with Ibuprofen and celecoxib in patients with osteoarthritis. The Journal of rheumatology, 2004, Volume: 31, Issue:9 Topics: Aged; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Female; Humans; Ibuprofen; Incidence; Male; Middle Aged; Organic Chemicals; Osteoarthritis; Peptic Ulcer; Pyrazoles; Risk Factors; Sulfonamides	2004
Lumiracoxib. Drugs, 2004, Volume: 64, Issue:19 Topics: Administration, Oral; Arthritis, Rheumatoid; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Drug Administration Schedule; Drug Evaluation, Preclinical; Female; Half-Life; Humans; Male; Molecular Structure; New Zealand; Organic Chemicals; Osteoarthritis; Oxycodone; Pain; Pyrazoles; Sulfonamides; Terminology as Topic; World Health Organization	2004
Safety and efficacy of lumiracoxib compared with NSAIDs. Nature clinical practice. Gastroenterology & hepatology, 2005, Volume: 2, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Diclofenac; Double-Blind Method; Drug Therapy, Combination; Follow-Up Studies; Gastrointestinal Diseases; Humans; Incidence; Organic Chemicals; Osteoarthritis; Risk Factors; Time Factors; Treatment Outcome	2005
Evaluation of the patient acceptable symptom state in a pooled analysis of two multicentre, randomised, double-blind, placebo-controlled studies evaluating lumiracoxib and celecoxib in patients with osteoarthritis. Arthritis research & therapy, 2007, Volume: 9, Issue:1 Topics: Aged; Celecoxib; Diclofenac; Double-Blind Method; Female; Humans; Male; Middle Aged; Osteoarthritis; Pain Measurement; Patient Satisfaction; Pyrazoles; Sulfonamides	2007
Cardiovascular outcomes in high risk patients with osteoarthritis treated with ibuprofen, naproxen or lumiracoxib. Annals of the rheumatic diseases, 2007, Volume: 66, Issue:6 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Cyclooxygenase 2 Inhibitors; Diclofenac; Double-Blind Method; Drug Therapy, Combination; Female; Heart Defects, Congenital; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Osteoarthritis	2007
Effect of risk factors on complicated and uncomplicated ulcers in the TARGET lumiracoxib outcomes study. Gastroenterology, 2007, Volume: 133, Issue:1 Topics: Age Distribution; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2 Inhibitors; Diclofenac; Duodenal Ulcer; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Osteoarthritis; Risk Factors; Risk Reduction Behavior; Stomach Ulcer	2007
Long-term retention on treatment with lumiracoxib 100 mg once or twice daily compared with celecoxib 200 mg once daily: a randomised controlled trial in patients with osteoarthritis. BMC musculoskeletal disorders, 2008, Mar-07, Volume: 9 Topics: Aged; Arthralgia; Canada; Cardiovascular Diseases; Celecoxib; Chemical and Drug Induced Liver Injury; Cyclooxygenase 2 Inhibitors; Diclofenac; Double-Blind Method; Drug Administration Schedule; Europe; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Osteoarthritis; Pain Measurement; Pyrazoles; Sulfonamides; Time Factors; Treatment Outcome; United States	2008

Other Studies

6 other study(ies) available for cox 189 and Arthritis, Degenerative

Article	Year
Severe acute liver injury associated with lumiracoxib. Journal of gastroenterology and hepatology, 2012, Volume: 27, Issue:6 Topics: Acute Disease; Autoantibodies; Chemical and Drug Induced Liver Injury; Cyclooxygenase 2 Inhibitors; Diclofenac; Fatal Outcome; Female; Humans; Liver Transplantation; Middle Aged; Osteoarthritis	2012
Evidence in practice--number 3: Cox 2 inhibitors. The British journal of general practice : the journal of the Royal College of General Practitioners, 2004, Volume: 54, Issue:508 Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Diclofenac; Evidence-Based Medicine; Humans; Ibuprofen; Middle Aged; Naproxen; Organic Chemicals; Osteoarthritis; Stomach Ulcer	2004
COX-2 drug may help treat osteoarthritis. Health news (Waltham, Mass.), 2004, Volume: 10, Issue:12 Topics: Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Humans; Isoenzymes; Membrane Proteins; Organic Chemicals; Osteoarthritis; Prostaglandin-Endoperoxide Synthases	2004
Lumiracoxib in the treatment of osteoarthritis, rheumatoid arthritis and acute postoperative dental pain: results of three dose-response studies. Current medical research and opinion, 2005, Volume: 21, Issue:1 Topics: Adolescent; Adult; Aged; Analysis of Variance; Arthritis, Rheumatoid; Clinical Trials, Phase II as Topic; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Female; Humans; Logistic Models; Male; Middle Aged; Multicenter Studies as Topic; Organic Chemicals; Osteoarthritis; Pain, Postoperative; Randomized Controlled Trials as Topic; Tooth Extraction; Treatment Outcome	2005
Australian drugs regulator cancels registration of COX 2 inhibitor. BMJ (Clinical research ed.), 2007, Aug-25, Volume: 335, Issue:7616 Topics: Australia; Cyclooxygenase 2 Inhibitors; Diclofenac; Drug Approval; Humans; Osteoarthritis	2007
Advice for nurses on drug withdrawal. Australian nursing journal (July 1993), 2007, Volume: 15, Issue:3 Topics: Acetaminophen; Analgesics, Non-Narcotic; Australia; Cyclooxygenase 2 Inhibitors; Diclofenac; Drug Approval; Humans; Osteoarthritis	2007