Page last updated: 2024-09-04

cox 189 and Ache

cox 189 has been researched along with Ache in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (71.43)29.6817
2010's4 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bartzatt, R1
Adekunle, F; Andrews, C; Ellis, G; Kinch, H; Kyle, C; Zachariah, J1
Bakhle, YS; de Francischi, JN; dos Reis, WG; Ferreira-Alves, DL; Gassani, BC; Paiva-Lima, P; Rezende, RM1
Dattani, ID; Maxwell, T; Moore, A; Rebuli, R; Sallstig, P; Schneider, H; Schnitzer, TJ; Seriolo, B; Tseng, L1
Castañeda-Hernández, G; Jiménez-Andrade, JM; Ortiz, MI; Trocóniz, IF; Vásquez-Bahena, D; Vélez de Mendizábal, N1
Bevan, S; Courade, JP; Dawson, J; Fox, A; Glatt, M; Gonzalez, I; Medhurst, S; Urban, L1
Mysler, E1
Beier, J; Geusens, P; Gitton, X; Hasler, P; Moore, A; Patel, SK; Poór, G; Schnitzer, TJ; Senftleber, I; Sloan, VS1
Curran, MP; Lyseng-Williamson, KA1
Castañeda-Hernández, G; Granados-Soto, V; Lozano-Cuenca, J1
Dutta, D; Fleischmann, R; Maldonado-Cocco, J; Sheldon, E; Sloan, VS; Yu, S1
Bannwarth, B; Bérenbaum, F1
Duh, D; Vandevijver, A1
Klotz, U; Shi, S1

Reviews

3 review(s) available for cox 189 and Ache

ArticleYear
Lumiracoxib (Prexige): a new selective COX-2 inhibitor.
    International journal of clinical practice, 2004, Volume: 58, Issue:6

    Topics: Acute Disease; Chronic Disease; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Drug Evaluation; Drug Interactions; Gastrointestinal Diseases; Humans; Isoenzymes; Membrane Proteins; Organic Chemicals; Pain; Prostaglandin-Endoperoxide Synthases

2004
Lumiracoxib in the management of osteoarthritis and acute pain.
    Expert opinion on pharmacotherapy, 2007, Volume: 8, Issue:10

    Topics: Acute Disease; Animals; Cardiovascular Diseases; Cyclooxygenase 2 Inhibitors; Diclofenac; Drug Approval; Humans; Osteoarthritis; Pain; Peptic Ulcer; Risk Assessment; Treatment Outcome

2007
Clinical use and pharmacological properties of selective COX-2 inhibitors.
    European journal of clinical pharmacology, 2008, Volume: 64, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Drug Monitoring; Etoricoxib; Humans; Osteoarthritis; Pain; Pyrazoles; Pyridines; Sulfonamides; Sulfones

2008

Trials

5 trial(s) available for cox 189 and Ache

ArticleYear
A randomised, double-blind study comparing lumiracoxib with naproxen for acute musculoskeletal pain.
    International journal of clinical practice, 2008, Volume: 62, Issue:11

    Topics: Acute Disease; Adult; Cyclooxygenase 2 Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Musculoskeletal Diseases; Naproxen; Pain; Treatment Outcome

2008
A 13-week, multicenter, randomized, double-blind study of lumiracoxib in hip osteoarthritis.
    Clinical rheumatology, 2011, Volume: 30, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Cyclooxygenase 2 Inhibitors; Diclofenac; Double-Blind Method; Female; Humans; Male; Middle Aged; Osteoarthritis, Hip; Pain; Pain Measurement; Treatment Outcome

2011
Efficacy and safety of four doses of lumiracoxib versus diclofenac in patients with knee or hip primary osteoarthritis: a phase II, four-week, multicenter, randomized, double-blind, placebo-controlled trial.
    Arthritis and rheumatism, 2004, Aug-15, Volume: 51, Issue:4

    Topics: Aged; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Female; Health Status; Humans; Male; Middle Aged; Organic Chemicals; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain; Placebos; Surveys and Questionnaires; Treatment Outcome

2004
Lumiracoxib.
    Drugs, 2004, Volume: 64, Issue:19

    Topics: Administration, Oral; Arthritis, Rheumatoid; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Drug Administration Schedule; Drug Evaluation, Preclinical; Female; Half-Life; Humans; Male; Molecular Structure; New Zealand; Organic Chemicals; Osteoarthritis; Oxycodone; Pain; Pyrazoles; Sulfonamides; Terminology as Topic; World Health Organization

2004
Lumiracoxib is effective in the treatment of osteoarthritis of the knee: a prospective randomized 13-week study versus placebo and celecoxib.
    Clinical rheumatology, 2006, Volume: 25, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Organic Chemicals; Osteoarthritis, Knee; Pain; Pain Measurement; Prospective Studies; Pyrazoles; Sulfonamides; Treatment Outcome

2006

Other Studies

6 other study(ies) available for cox 189 and Ache

ArticleYear
Drug analogs of COX-2 selective inhibitors lumiracoxib and valdecoxib derived from in silico search and optimization.
    Anti-inflammatory & anti-allergy agents in medicinal chemistry, 2014, Volume: 13, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Computer Simulation; Cyclooxygenase 2 Inhibitors; Diclofenac; Drug Design; Humans; Isoxazoles; Models, Molecular; Neoplasms; Pain; Sulfonamides

2014
Is the sulphonamide radical in the celecoxib molecule essential for its analgesic activity?
    Pharmacological research, 2010, Volume: 62, Issue:5

    Topics: Acetazolamide; Animals; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Hyperalgesia; Inflammation; Male; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Pain Threshold; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides

2010
Semi-mechanistic modeling of the interaction between the central and peripheral effects in the antinociceptive response to lumiracoxib in rats.
    The AAPS journal, 2012, Volume: 14, Issue:4

    Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diclofenac; Disease Models, Animal; Female; Formaldehyde; Injections; Injections, Spinal; Models, Biological; Nonlinear Dynamics; Pain; Pain Measurement; Rats; Rats, Wistar; Time Factors; Up-Regulation

2012
Anti-hyperalgesic activity of the cox-2 inhibitor lumiracoxib in a model of bone cancer pain in the rat.
    Pain, 2004, Volume: 107, Issue:1-2

    Topics: Analysis of Variance; Animals; Behavior, Animal; Bone Density; Bone Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Freund's Adjuvant; Hyperalgesia; Inflammation; Isoenzymes; Isoxazoles; Organic Chemicals; Pain; Pain Measurement; Prostaglandin-Endoperoxide Synthases; Radiology; Rats; Rats, Sprague-Dawley; Sulfonamides; Time Factors; Tumor Cells, Cultured

2004
Peripheral and spinal mechanisms of antinociceptive action of lumiracoxib.
    European journal of pharmacology, 2005, Apr-18, Volume: 513, Issue:1-2

    Topics: Analgesics; Animals; Apamin; Behavior, Animal; Charybdotoxin; Diclofenac; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Formaldehyde; Glyburide; Guanylate Cyclase; Hindlimb; Injections, Spinal; Injections, Subcutaneous; Methiothepin; Naloxone; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Organic Chemicals; Oxadiazoles; Pain; Pain Measurement; Quinoxalines; Rats; Rats, Wistar; Scorpion Venoms

2005
[Lumiracoxib--Prexigem].
    Journal de pharmacie de Belgique, 2007, Volume: 62, Issue:3

    Topics: Arthritis; Cyclooxygenase 2 Inhibitors; Diclofenac; Humans; Pain

2007