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coumarin and Pulmonary Embolism

coumarin has been researched along with Pulmonary Embolism in 21 studies

2H-chromen-2-one: coumarin derivative

Pulmonary Embolism: Blocking of the PULMONARY ARTERY or one of its branches by an EMBOLUS.

Research Excerpts

ExcerptRelevanceReference
" with coumarin) is still the most widely used treatment for deep venous thromboembolism."9.07Comparison of subcutaneous unfractionated heparin with a low molecular weight heparin (Fragmin) in patients with venous thromboembolism and contraindications to coumarin. ( del Rio, L; Lafoz, E; Monreal, M; Olive, A; Vedia, C, 1994)
"A 57-year-old male patient with advanced adenocarcinoma of the lung, who was administered oral anticoagulant therapy because of pulmonary embolism, developed coumarin necrosis confined to the penis and feet."8.80A case of coumarin necrosis with penile and pedal involvement. ( Baloğlu, H; Başak, M; Doğan, B; Harmanyeri, Y; Taşkapan, O, 1998)
"Coumarin-induced necrosis of the skin and subcutaneous tissue is an uncommon but well recognized complication of anticoagulant therapy."8.77Coumarin necrosis of the penis. ( Badalament, RA; Barkley, C; Drago, JR; Metz, EN; Nesbitt, J, 1989)
"In three patients painful reddening of a well-circumscribed area of the skin occurred within five days of starting anticoagulant treatment with phenprocoumon (Marcumar), and within a short time it developed into a full-blown picture of coumarin necrosis."7.68[The clinical course of coumarin-induced necrosis]. ( Ellbrück, D; Rasche, H; Seifried, E; Wankmüller, H, 1991)
"Defiency of protein C has been reported to be associated with recurrent thrombosis and pulmonary embolism, disseminated intravascular coagulation, and coumarin-induced skin necrosis and peripheral gangrene."7.67Recurrent thromboembolism, disseminated intravascular coagulation, and coumarin-induced skin necrosis associated with protein C deficiency. ( Lie, JT, 1988)
" with coumarin) is still the most widely used treatment for deep venous thromboembolism."5.07Comparison of subcutaneous unfractionated heparin with a low molecular weight heparin (Fragmin) in patients with venous thromboembolism and contraindications to coumarin. ( del Rio, L; Lafoz, E; Monreal, M; Olive, A; Vedia, C, 1994)
"A 57-year-old male patient with advanced adenocarcinoma of the lung, who was administered oral anticoagulant therapy because of pulmonary embolism, developed coumarin necrosis confined to the penis and feet."4.80A case of coumarin necrosis with penile and pedal involvement. ( Baloğlu, H; Başak, M; Doğan, B; Harmanyeri, Y; Taşkapan, O, 1998)
"Coumarin-induced necrosis of the skin and subcutaneous tissue is an uncommon but well recognized complication of anticoagulant therapy."4.77Coumarin necrosis of the penis. ( Badalament, RA; Barkley, C; Drago, JR; Metz, EN; Nesbitt, J, 1989)
" Introduction of coumarin therapy for venous thromboembolism should be started on day 1 of diagnosis, keeping the total duration of heparin therapy at no more than five days and therefore minimizing the incidence of heparin-induced thrombocytopenia."3.72[Anticoagulation in patients with venous thromboembolism]. ( Rüfer, A; Wuillemin, WA, 2003)
"Long-term favourable effects of a treatment with both cyclosporin A and coumarin in a 35 year old Caucasian female patient with Behçet's disease, presenting with haemoptysis caused by pulmonary thromboemboli and a single major pulmonary artery aneurysm, are reported."3.70Long-term treatment with cyclosporin A and coumarin in pulmonary thromboembolic Behçet's disease. ( Demedts, M; Van Haecke, P; Vansteenkiste, J, 1998)
"In three patients painful reddening of a well-circumscribed area of the skin occurred within five days of starting anticoagulant treatment with phenprocoumon (Marcumar), and within a short time it developed into a full-blown picture of coumarin necrosis."3.68[The clinical course of coumarin-induced necrosis]. ( Ellbrück, D; Rasche, H; Seifried, E; Wankmüller, H, 1991)
"Defiency of protein C has been reported to be associated with recurrent thrombosis and pulmonary embolism, disseminated intravascular coagulation, and coumarin-induced skin necrosis and peripheral gangrene."3.67Recurrent thromboembolism, disseminated intravascular coagulation, and coumarin-induced skin necrosis associated with protein C deficiency. ( Lie, JT, 1988)
"One fatal suspected pulmonary embolism in a patient with metastatic cancer was judged to be possibly PCC-related."2.73Prothrombin complex concentrate (Beriplex P/N) for emergency anticoagulation reversal: a prospective multinational clinical trial. ( Brenner, B; Kalina, U; Knaub, S; Nagy, A; Ostermann, H; Pabinger, I, 2008)
"Once- or twice-daily subcutaneous dosing of LMWHs without laboratory monitoring has facilitated outpatient VTE therapy."2.42Outpatient treatment of acute venous thromboembolic disease. ( Gage, BF; Yusen, RD, 2003)
"Non-fatal pulmonary embolism after onset of treatment occurred in both cohorts with an equal frequency of 13%."1.28Surgical thrombectomy versus conservative treatment for deep venous thrombosis; functional comparison of long-term results. ( Gänger, KH; Nachbur, BH; Ris, HB; Zurbrügg, H, 1989)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199010 (47.62)18.7374
1990's6 (28.57)18.2507
2000's5 (23.81)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rüfer, A1
Wuillemin, WA1
Yusen, RD1
Gage, BF1
PIRKEY, WP1
MARKS, J1
TRUSCOTT, BM1
WITHYCOMBE, JF1
THOYER-ROZAT, J1
VASSY, S1
FAIVRE, G1
GILGENKRANTZ, JM1
CHERRIER, F1
TENETTE, C1
BARRUCAND, D1
NALBANDIAN, RM1
MADER, IJ1
BARRETT, JL1
PEARCE, JF1
RUPP, EC1
de GENNES, L1
Richter, ON1
Rath, W1
Lobo, JL1
Jiménez, D1
Teresa Orue, M1
Grau, E1
Naufall, D1
Madridano, O1
Monreal, M2
Pabinger, I1
Brenner, B1
Kalina, U1
Knaub, S1
Nagy, A1
Ostermann, H1
Lafoz, E1
Olive, A1
del Rio, L1
Vedia, C1
Harmanyeri, Y1
Taşkapan, O1
Doğan, B1
Baloğlu, H1
Başak, M1
Vansteenkiste, J1
Van Haecke, P1
Demedts, M1
Hyers, TM1
Agnelli, G1
Hull, RD1
Weg, JG1
Morris, TA1
Samama, M1
Tapson, V1
van Heusden, AM1
Merkus, HM1
Dullemond-Westland, AC1
Ellbrück, D1
Wankmüller, H1
Rasche, H1
Seifried, E1
Barkley, C1
Badalament, RA1
Metz, EN1
Nesbitt, J1
Drago, JR1
Gänger, KH1
Nachbur, BH1
Ris, HB1
Zurbrügg, H1
Lie, JT1
Lang, SJ1
Mulder, DG1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy and Tolerance of BERIPLEX® P/N in Subjects With Acquired Deficiency of Coagulation Factors II, VII, IX and X Due to Oral Anticoagulation[NCT00168077]Phase 340 participants Interventional2005-09-30Completed
Efficacy of Prothrombin Complex Concentrate Reducing Perioperative Blood Loss in Cardiac Surgery, Compared With Fresh Frozen Plasma: Study Protocol for a Non-inferiority, Randomized Controlled Trial[NCT04244981]Phase 4796 participants (Anticipated)Interventional2023-12-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for coumarin and Pulmonary Embolism

ArticleYear
Outpatient treatment of acute venous thromboembolic disease.
    Clinics in chest medicine, 2003, Volume: 24, Issue:1

    Topics: Acute Disease; Ambulatory Care; Anticoagulants; Coumarins; Fibrinolytic Agents; Heparin; Heparin, Lo

2003
[Thromboembolic diseases in pregnancy].
    Zeitschrift fur Geburtshilfe und Neonatologie, 2007, Volume: 211, Issue:1

    Topics: Algorithms; Anticoagulants; Aspirin; Contraindications; Coumarins; Female; Heparin; Heparin, Low-Mol

2007
A case of coumarin necrosis with penile and pedal involvement.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 1998, Volume: 10, Issue:3

    Topics: Adenocarcinoma; Anticoagulants; Coumarins; Foot Dermatoses; Humans; Lung Neoplasms; Male; Middle Age

1998
Antithrombotic therapy for venous thromboembolic disease.
    Chest, 1998, Volume: 114, Issue:5 Suppl

    Topics: Coumarins; Fibrinolytic Agents; Heparin; Heparin, Low-Molecular-Weight; Humans; Pulmonary Embolism;

1998
Coumarin necrosis of the penis.
    The Journal of urology, 1989, Volume: 141, Issue:4

    Topics: Coumarins; Humans; Male; Middle Aged; Necrosis; Penis; Protein C Deficiency; Pulmonary Embolism

1989

Trials

2 trials available for coumarin and Pulmonary Embolism

ArticleYear
Prothrombin complex concentrate (Beriplex P/N) for emergency anticoagulation reversal: a prospective multinational clinical trial.
    Journal of thrombosis and haemostasis : JTH, 2008, Volume: 6, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Coumarins; Drug Combinations; Emergencies; Europe; F

2008
Prothrombin complex concentrate (Beriplex P/N) for emergency anticoagulation reversal: a prospective multinational clinical trial.
    Journal of thrombosis and haemostasis : JTH, 2008, Volume: 6, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Coumarins; Drug Combinations; Emergencies; Europe; F

2008
Prothrombin complex concentrate (Beriplex P/N) for emergency anticoagulation reversal: a prospective multinational clinical trial.
    Journal of thrombosis and haemostasis : JTH, 2008, Volume: 6, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Coumarins; Drug Combinations; Emergencies; Europe; F

2008
Prothrombin complex concentrate (Beriplex P/N) for emergency anticoagulation reversal: a prospective multinational clinical trial.
    Journal of thrombosis and haemostasis : JTH, 2008, Volume: 6, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Coumarins; Drug Combinations; Emergencies; Europe; F

2008
Comparison of subcutaneous unfractionated heparin with a low molecular weight heparin (Fragmin) in patients with venous thromboembolism and contraindications to coumarin.
    Thrombosis and haemostasis, 1994, Volume: 71, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Contraindications; Coumarins; Dalteparin; Female; Fractures, Spontan

1994

Other Studies

14 other studies available for coumarin and Pulmonary Embolism

ArticleYear
[Anticoagulation in patients with venous thromboembolism].
    Therapeutische Umschau. Revue therapeutique, 2003, Volume: 60, Issue:1

    Topics: Anticoagulants; Bandages; Clinical Trials as Topic; Coumarins; Fibrinolytic Agents; Heparin; Heparin

2003
Pulmonary embolus following tonsillectomy; report of a case.
    The Laryngoscope, 1953, Volume: 63, Issue:12

    Topics: Coumarins; Femoral Vein; Heparin; Humans; Pulmonary Embolism; Thrombosis; Tonsillectomy

1953
Treatment of venous thrombosis with anticoagulants; review of 1135 cases.
    Lancet (London, England), 1954, Oct-16, Volume: 267, Issue:6842

    Topics: Anticoagulants; Coumarins; Heparin; Humans; Phenindione; Pulmonary Embolism; Thrombosis; Venous Thro

1954
[Postoperative phlebitis and pulmonary embolism caused by early ambulation and anticoagulants].
    Bulletin de la Federation des societes de gynecologie et dobstetrique de langue francaise, 1954, Volume: 6, Issue:5

    Topics: Anticoagulants; Coumarins; Early Ambulation; Female; Humans; Phlebitis; Postoperative Care; Postpart

1954
[CRITICAL STUDY, BASED ON 43 CASES, OF A COUMARIN ANTICOAGULANT: DICOUMOXYL (1-METHOXY-2,2-BIS-(4-HYDROXY-3-COU- MARINYL)-ETHANE)].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1963, Nov-08, Volume: 39

    Topics: Anticoagulants; Arrhythmias, Cardiac; Coronary Disease; Coumarins; Ethane; Mitral Valve Stenosis; My

1963
PETECHIAE, ECCHYMOSES, AND NECROSIS OF SKIN INDUCED BY COUMARIN CONGENERS: RARE, OCCASIONALLY LETHAL COMPLICATION OF ANTICOAGULANT THERAPY.
    JAMA, 1965, May-17, Volume: 192

    Topics: Acenocoumarol; Anticoagulants; Coumarins; Dicumarol; Drug Therapy; Ecchymosis; Ethyl Biscoumacetate;

1965
[Pulmonary embolism as a cause of hemorrhage in two phlebitis cases treated with tromexane].
    La Presse medicale, 1952, Jan-19, Volume: 60, Issue:4

    Topics: Coumarins; Phlebitis; Pulmonary Embolism

1952
Recurrent venous thromboembolism during coumarin therapy. Data from the computerised registry of patients with venous thromboembolism.
    British journal of haematology, 2007, Volume: 138, Issue:3

    Topics: Aged; Coumarins; Female; Humans; Male; Middle Aged; Pulmonary Embolism; Recurrence; Registries; Veno

2007
Long-term treatment with cyclosporin A and coumarin in pulmonary thromboembolic Behçet's disease.
    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 1998, Volume: 53, Issue:2

    Topics: Adult; Aneurysm; Anticoagulants; Behcet Syndrome; Coumarins; Cyclosporine; Drug Therapy, Combination

1998
Pregnancy and protein C deficiency.
    European journal of obstetrics, gynecology, and reproductive biology, 1992, Jul-24, Volume: 45, Issue:3

    Topics: Adult; Coumarins; Female; Fetal Death; Heparin; Humans; Pregnancy; Pregnancy Complications, Hematolo

1992
[The clinical course of coumarin-induced necrosis].
    Deutsche medizinische Wochenschrift (1946), 1991, Aug-30, Volume: 116, Issue:35

    Topics: Adult; Coumarins; Drug Hypersensitivity; Drug Therapy, Combination; Female; Heparin; Humans; Middle

1991
Surgical thrombectomy versus conservative treatment for deep venous thrombosis; functional comparison of long-term results.
    European journal of vascular surgery, 1989, Volume: 3, Issue:6

    Topics: Bandages; Combined Modality Therapy; Coumarins; Drug Therapy, Combination; Follow-Up Studies; Hepari

1989
Recurrent thromboembolism, disseminated intravascular coagulation, and coumarin-induced skin necrosis associated with protein C deficiency.
    Pathology, research and practice, 1988, Volume: 183, Issue:3

    Topics: Adolescent; Blood Coagulation; Coumarins; Disseminated Intravascular Coagulation; Female; Gangrene;

1988
Thromboembolic obstruction of the pulmonary artery treated by endarterectomy.
    The Annals of thoracic surgery, 1986, Volume: 41, Issue:5

    Topics: Adult; Angiography; Cardiopulmonary Bypass; Coumarins; Endarterectomy; Humans; Male; Prognosis; Pulm

1986