Page last updated: 2024-10-17

coumarin and Pregnancy

coumarin has been researched along with Pregnancy in 45 studies

2H-chromen-2-one: coumarin derivative

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
" The major clinical features of CDP also present in a phenocopy known as coumarin embryopathy (CE) which results from coumarin exposure during pregnancy."8.88Natural history and management of cervical spine disease in chondrodysplasia punctata and coumarin embryopathy. ( Menezes, AH; Vogel, TW, 2012)
"Hemorrhagic skin necrosis of the toes was observed in a patient with heterozygous protein C deficiency (protein C:Ag 32% and protein C activity 30%) on the 4th day of coumarin treatment overlapping with effective intravenous anticoagulation with heparin."7.67Coumarin induced acral skin necrosis associated with hereditary protein C deficiency. ( Karnik, R; Lechner, K; Niessner, H; Pabinger, I; Slany, J, 1986)
" The major clinical features of CDP also present in a phenocopy known as coumarin embryopathy (CE) which results from coumarin exposure during pregnancy."4.88Natural history and management of cervical spine disease in chondrodysplasia punctata and coumarin embryopathy. ( Menezes, AH; Vogel, TW, 2012)
" Coumarin derivatives provide adequate protection against thromboembolism and should be used during pregnancy in patients with mechanical prostheses."4.81[Heart disease, anticoagulants and pregnancy]. ( Izaguirre, R; Salazar, E, 2001)
" Female mice were injected intraperitoneally with ethylnitrosourea (ENU) on the 10th day of pregnancy and received 3 successive oral administrations of vanillin."3.68Suppression of 6-TG-resistant mutations in V79 cells and recessive spot formations in mice by vanillin. ( Imanishi, H; Matsumoto, K; Ohta, T; Sasaki, YF; Shirasu, Y; Tutikawa, K; Watanabe, M, 1990)
"Coumarins administered in early pregnancy can cause malformations."3.67[Teratogenic effect of coumarins]. ( Canzler, E; Hundsdörfer, S; Zipprich, K, 1987)
"Hemorrhagic skin necrosis of the toes was observed in a patient with heterozygous protein C deficiency (protein C:Ag 32% and protein C activity 30%) on the 4th day of coumarin treatment overlapping with effective intravenous anticoagulation with heparin."3.67Coumarin induced acral skin necrosis associated with hereditary protein C deficiency. ( Karnik, R; Lechner, K; Niessner, H; Pabinger, I; Slany, J, 1986)
"Generalized osteoporosis is a result of different causes and pathogenic mechanisms, which often combine forces to become clinically relevant."1.31[Secondary osteoporosis induced by anticoagulants?]. ( Himmelreich, G; Loew, A; Riess, H, 2001)

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-199020 (44.44)18.7374
1990's11 (24.44)18.2507
2000's8 (17.78)29.6817
2010's5 (11.11)24.3611
2020's1 (2.22)2.80

Authors

AuthorsStudies
Sohail, R1
Bashir, A1
Safdar, Z1
Noreen, A1
Yu, A1
Li, Q1
Zhan, Y1
He, J1
Anderson, T1
Haake, S1
Lane, AR1
Hackney, AC1
Liu, X1
Li, T1
Zhao, X1
Suo, H1
Zhang, Z1
Zhao, P1
Gao, S1
Niu, M1
Yang, Q1
Li, G1
Xia, H1
Liu, Z2
Jiang, J1
Zhuang, T1
Urakawa, M1
Sato, H1
Sato, Y1
Taguchi, T1
Umino, T1
Katto, S1
Tanaka, K1
Yoshimura, K1
Takada, N1
Kobayashi, H1
Ito, M1
Rose, MT1
Kiku, Y1
Nagasawa, Y1
Kitazawa, H1
Watanabe, K1
Nochi, T1
Hayashi, T1
Aso, H1
Yan, H1
Gao, X1
Zhang, Y2
Chang, W1
Li, J1
Li, X1
Du, Q1
Li, C1
Tahara, S1
Takeuchi, S1
Abe-Yoshizumi, R1
Inoue, K1
Ohtani, H1
Kandori, H1
Tahara, T1
Ye, R1
Chen, Y1
Tang, L1
Wang, Q2
Li, B1
Zhou, X1
Liu, J1
Hu, J1
George, ES1
Marshall, S1
Mayr, HL1
Trakman, GL1
Tatucu-Babet, OA1
Lassemillante, AM1
Bramley, A1
Reddy, AJ1
Forsyth, A1
Tierney, AC1
Thomas, CJ1
Itsiopoulos, C1
Marx, W1
Allignol, A1
Schumacher, M2
Beyersmann, J2
Regitz-Zagrosek, V1
Seeland, U1
Geibel-Zehender, A1
Gohlke-Bärwolf, C1
Kruck, I1
Schaefer, C1
Vogel, TW1
Menezes, AH1
Di Termini, S1
Hieke, S1
Al-Lawati, AA1
Venkitraman, M1
Al-Delaime, T1
Valliathu, J1
DE NICOLA, P1
KNAKE, HJ1
VILMAR, E1
SCHIAVINA, P1
SCHIAVINA, GP1
MATERNE, M1
NIJENHUIS, WT1
MEIXNER, H2
SZIRMAI, E3
UEBELHART, R1
STRAULI, P1
DEIMEL, H1
VAN ASSEN, FJ1
KOOY, HJ1
BIANCHI, M1
CRAVAREZZA, F1
MANSELL, RV1
Richter, ON1
Rath, W1
Lee, JH1
Park, NH1
Keum, DY1
Choi, SY1
Kwon, KY1
Cho, CH1
Bader, R1
Mannucci, PM1
Tripodi, A1
Hirsh, J1
Keller, F1
Solleder, EM1
Hawkins, P1
Peng, M1
Pelzer, H1
Teijidor, LM1
Bauer, KA1
Lecuru, F1
Desnos, M1
Taurelle, R1
Balestrieri, C1
Camussi, G1
Giovane, A1
Iorio, EL1
Quagliuolo, L1
Servillo, L1
Mischke, R1
Hellmold, H1
Magnusson, M1
Pelto-Huikko, M1
Rylander, T1
Gustafsson, J1
Warner, M1
James, PR1
Clark, SL1
Porter, TF1
West, FG1
Brechmann, J1
Unterberg, C1
Riess, H1
Loew, A1
Himmelreich, G1
Salazar, E1
Izaguirre, R1
van Heusden, AM1
Merkus, HM1
Dullemond-Westland, AC1
Ayhan, A1
Yapar, EG1
Yüce, K1
Kişnişci, HA1
Nazli, N1
Ozmen, F1
Levine, MN1
Anderson, DR1
Imanishi, H1
Sasaki, YF1
Matsumoto, K1
Watanabe, M1
Ohta, T1
Shirasu, Y1
Tutikawa, K1
Barnea, ER1
Avigdor, S1
Zipprich, K1
Canzler, E1
Hundsdörfer, S1
Pabinger, I1
Karnik, R1
Lechner, K1
Slany, J1
Niessner, H1
Pawlow, V1
Pawlow, I1
Schardein, JL1

Reviews

8 reviews available for coumarin and Pregnancy

ArticleYear
    European radiology experimental, 2017, Volume: 1, Issue:1

    Topics: Adaptive Immunity; Amines; Animals; Antigen Presentation; Carbon Dioxide; Carcinoma, Hepatocellular;

2017
Cardiovascular diseases in pregnancy.
    Deutsches Arzteblatt international, 2011, Volume: 108, Issue:16

    Topics: Anticoagulants; Cardiomyopathies; Coumarins; Cross-Sectional Studies; Dose-Response Relationship, Dr

2011
Natural history and management of cervical spine disease in chondrodysplasia punctata and coumarin embryopathy.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2012, Volume: 28, Issue:4

    Topics: Adult; Cervical Vertebrae; Chondrodysplasia Punctata; Coumarins; Disease Management; Female; Fetal D

2012
[Thromboembolic diseases in pregnancy].
    Zeitschrift fur Geburtshilfe und Neonatologie, 2007, Volume: 211, Issue:1

    Topics: Algorithms; Anticoagulants; Aspirin; Contraindications; Coumarins; Female; Heparin; Heparin, Low-Mol

2007
Management of patients with hereditary defects predisposing to thrombosis including pregnant women.
    Thrombosis and haemostasis, 1995, Volume: 74, Issue:1

    Topics: Abnormalities, Drug-Induced; Anticoagulants; Antithrombin III; Antithrombin III Deficiency; Blood Pr

1995
[Heart disease, anticoagulants and pregnancy].
    Revista espanola de cardiologia, 2001, Volume: 54 Suppl 1

    Topics: Abortion, Spontaneous; Adult; Anticoagulants; Coumarins; Female; Fetus; Gestational Age; Heart Valve

2001
Side-effects of antithrombotic therapy.
    Bailliere's clinical haematology, 1990, Volume: 3, Issue:3

    Topics: Administration, Oral; Adult; Animals; Anticoagulants; Coumarins; Drug Eruptions; Drug Hypersensitivi

1990
Current status of drugs as teratogens in man.
    Progress in clinical and biological research, 1985, Volume: 163C

    Topics: Abnormalities, Drug-Induced; Anti-Bacterial Agents; Anticonvulsants; Antineoplastic Agents; Coumarin

1985

Trials

3 trials available for coumarin and Pregnancy

ArticleYear
Low molecular weight heparin treatment in pregnant women with a mechanical heart valve prosthesis.
    Journal of Korean medical science, 2007, Volume: 22, Issue:2

    Topics: Adult; Coumarins; Female; Heart Valve Diseases; Heart Valve Prosthesis; Humans; Hydrocephalus; Nadro

2007
Anticoagulant therapy in pregnancy. Report of 54 cases.
    Acta obstetricia et gynecologica Scandinavica, 1996, Volume: 75, Issue:3

    Topics: Adult; Anticoagulants; Chi-Square Distribution; Coumarins; Female; Fetus; Heart Valve Prosthesis; He

1996
Side-effects of antithrombotic therapy.
    Bailliere's clinical haematology, 1990, Volume: 3, Issue:3

    Topics: Administration, Oral; Adult; Animals; Anticoagulants; Coumarins; Drug Eruptions; Drug Hypersensitivi

1990

Other Studies

35 other studies available for coumarin and Pregnancy

ArticleYear
Successful pregnancy in a liver transplant patient of Budd-Chiari syndrome.
    BMJ case reports, 2020, Feb-09, Volume: 13, Issue:2

    Topics: Adult; Budd-Chiari Syndrome; Cesarean Section; Coumarins; Female; Humans; Liver Transplantation; Pre

2020
A note on variance estimation of the Aalen-Johansen estimator of the cumulative incidence function in competing risks, with a view towards left-truncated data.
    Biometrical journal. Biometrische Zeitschrift, 2010, Volume: 52, Issue:1

    Topics: Abortion, Spontaneous; Analysis of Variance; Computer Simulation; Coumarins; Data Interpretation, St

2010
Nonparametric inference for the cumulative incidence function of a competing risk, with an emphasis on confidence bands in the presence of left-truncation.
    Biometrical journal. Biometrische Zeitschrift, 2012, Volume: 54, Issue:4

    Topics: Abortion, Spontaneous; Analysis of Variance; Anticoagulants; Biometry; Coumarins; Female; Humans; Mo

2012
Pregnancy and mechanical heart valves replacement; dilemma of anticoagulation.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2002, Volume: 22, Issue:2

    Topics: Administration, Oral; Adult; Anticoagulants; Coumarins; Drug Administration Schedule; Female; Heart

2002
[Clinical significance of factor VII].
    Il Progresso medico, 1953, Feb-28, Volume: 9, Issue:4

    Topics: Blood Coagulation; Coumarins; Factor VII; Hemostatics; Heparin Antagonists; Humans; Infant, Newborn;

1953
[Dicumarol therapy in pregnancy; an animal-experimental contribution].
    Geburtshilfe und Frauenheilkunde, 1953, Volume: 13, Issue:5

    Topics: Animals; Child; Coumarins; Dicumarol; Female; Fetus; Humans; Infant; Infant, Newborn; Infant, Newbor

1953
[Clinical aspects of three cases of phlebothrombosis in pregnancy treated with anticoagulating substances (heparin, tromexan)].
    Minerva ginecologica, 1954, Apr-15, Volume: 6, Issue:7

    Topics: Anticoagulants; Coumarins; Ethyl Biscoumacetate; Female; Heparin; Humans; Pregnancy; Pregnancy Compl

1954
[Three cases of phlebothrombosis in pregnancy treated with anticoagulant substances].
    Quaderni di clinica ostetrica e ginecologica, 1954, Volume: 9

    Topics: Anticoagulants; Coumarins; Female; Heparin; Humans; Pregnancy; Pregnancy Complications; Thrombophleb

1954
[Dicumacyl in prevention of thromboembolic complications after gynecologic and obstetric operations].
    Belgisch tijdschrift voor geneeskunde, 1955, Jul-01, Volume: 11, Issue:13

    Topics: Biomedical Research; Coumarins; Female; Obstetric Surgical Procedures; Pregnancy; Thromboembolism

1955
[Effects on mother and infant of dicumacyl administration in pregnancy].
    Nederlands tijdschrift voor geneeskunde, 1955, Jul-09, Volume: 99, Issue:28

    Topics: Coumarins; Female; Fetus; Humans; Infant; Leg; Mothers; Pharmaceutical Preparations; Pregnancy; Preg

1955
[Specific treatment of thromboembolism in obstetrics and gynecology].
    Wiener medizinische Wochenschrift (1946), 1955, Jul-16, Volume: 105, Issue:28-29

    Topics: Anticoagulants; Coumarins; Female; Genital Diseases, Female; Gynecology; Heparin; Humans; Obstetrics

1955
[Dicumarin therapy in pregnant and non-pregnant women].
    Therapie der Gegenwart, 1955, Volume: 94, Issue:8

    Topics: Coumarins; Female; Humans; Pregnancy; Pregnancy Complications

1955
[The anticoagulant sintrom in obstetrics & gynecology].
    Wiener medizinische Wochenschrift (1946), 1957, Nov-02, Volume: 107, Issue:44

    Topics: Acenocoumarol; Analgesia; Anesthesia; Anesthesia and Analgesia; Anticoagulants; Coumarins; Female; G

1957
[Prophylaxis and therapy with the anticoagulant sintrom in gynecology and obstetrics].
    Schweizerische medizinische Wochenschrift, 1958, Mar-15, Volume: 88, Issue:11

    Topics: Acenocoumarol; Anticoagulants; Coumarins; Female; Genitalia; Genitalia, Female; Gynecology; Humans;

1958
[Hematoma in thrombosis prevention with sintrom after cesarean section].
    Geburtshilfe und Frauenheilkunde, 1958, Volume: 18, Issue:8

    Topics: Acenocoumarol; Anticoagulants; Cesarean Section; Coumarins; Diagnosis, Differential; Female; Hematom

1958
[Effects on mother and infant of dicumarol therapy in pregnancy].
    Nederlands tijdschrift voor geneeskunde, 1955, Jan-08, Volume: 99, Issue:2

    Topics: Blood Coagulation; Coumarins; Dicumarol; Female; Humans; Infant; Infant, Newborn; Infant, Newborn, D

1955
[Anticoagulant prophylaxis by marcumar in gynecology and obstetrics].
    Gazzetta medica italiana, 1955, Volume: 114, Issue:4

    Topics: Anticoagulants; Coumarins; Female; Genital Diseases, Female; Gynecologic Surgical Procedures; Gyneco

1955
[Therapeutic and diuretic effects of dicumarin in hydrops gravidarum].
    Magyar noorvosok lapja, 1951, Volume: 14, Issue:12

    Topics: Coumarins; Diuretics; Edema; Female; Humans; Pregnancy

1951
[The therapeutic and diuretic effect of dicoumarin in pregnancy dropsy].
    Gynaecologia. International monthly review of obstetrics and gynecology. Revue internationale mensuelle d'obstetrique et de gynecologie. Monatsschrift fur Geburtshilfe und Gynakologie, 1952, Volume: 133, Issue:4

    Topics: Coumarins; Dicumarol; Diuretics; Edema; Female; Pregnancy; Pregnancy Complications

1952
Antepartum dicumarol therapy.
    American journal of obstetrics and gynecology, 1952, Volume: 64, Issue:1

    Topics: Coumarins; Dicumarol; Female; Pregnancy; Pregnancy Complications; Thrombosis

1952
Multicentric evaluation of a new PT reagent based on recombinant human tissue factor and synthetic phospholipids.
    Thrombosis and haemostasis, 1994, Volume: 71, Issue:3

    Topics: Animals; Brain Chemistry; Calibration; Coumarins; Evaluation Studies as Topic; Female; Heparin; Huma

1994
Measurement of platelet-activating factor acetylhydrolase activity by quantitative high-performance liquid chromatography determination of coumarin-derivatized 1-O-alkyl-2-sn-lysoglyceryl-3-phosphorylcholine.
    Analytical biochemistry, 1996, Jan-15, Volume: 233, Issue:2

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Chromatography, High Pressure Liquid; Coumarins; Fem

1996
Evaluation of a prothrombin time optimized for the dog on plasmas with defined coagulation factor deficiency due to coumarin intoxication.
    Zentralblatt fur Veterinarmedizin. Reihe A, 1995, Volume: 42, Issue:9

    Topics: Animals; Blood Coagulation Disorders; Coumarins; Dog Diseases; Dogs; Female; Humans; Male; Pregnancy

1995
Identification of CYP2A3 as a major cytochrome P450 enzyme in the female peripubertal rat breast.
    Molecular pharmacology, 1998, Volume: 53, Issue:3

    Topics: Amino Acid Sequence; Animals; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Coumarins; Cytochrom

1998
Effect of pregnancy on the duration of bovine pericardial bioprostheses.
    American heart journal, 2000, Volume: 139, Issue:5

    Topics: Abnormalities, Drug-Induced; Animals; Anticoagulants; Bioprosthesis; Cattle; Coumarins; Female; Hear

2000
Coumarin derivatives and breast-feeding.
    Obstetrics and gynecology, 2000, Volume: 95, Issue:6 Pt 1

    Topics: Anticoagulants; Breast Feeding; Contraindications; Coumarins; Female; Humans; Molecular Structure; P

2000
[Superior vena cava thrombosis after in vitro fertilization].
    Deutsche medizinische Wochenschrift (1946), 2000, Nov-24, Volume: 125, Issue:47

    Topics: Abortion, Spontaneous; Adult; Anticoagulants; Coumarins; Estradiol; Female; Fertilization in Vitro;

2000
[Secondary osteoporosis induced by anticoagulants?].
    Der Orthopade, 2001, Volume: 30, Issue:7

    Topics: Administration, Oral; Adult; Anticoagulants; Bone and Bones; Bone Density; Clinical Trials as Topic;

2001
Pregnancy and protein C deficiency.
    European journal of obstetrics, gynecology, and reproductive biology, 1992, Jul-24, Volume: 45, Issue:3

    Topics: Adult; Coumarins; Female; Fetal Death; Heparin; Humans; Pregnancy; Pregnancy Complications, Hematolo

1992
Pregnancy and its complications after cardiac valve replacement.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 1991, Volume: 35, Issue:2

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adult; Coumarins; Female; Fetal Death; Heart Val

1991
Suppression of 6-TG-resistant mutations in V79 cells and recessive spot formations in mice by vanillin.
    Mutation research, 1990, Volume: 243, Issue:2

    Topics: Acrolein; Animals; Benzaldehydes; Cells, Cultured; Coumarins; Drug Resistance; Ethylnitrosourea; Fem

1990
Coordinated induction of estrogen hydroxylase and catechol-O-methyl transferase by xenobiotics in first trimester human placental explants.
    Journal of steroid biochemistry, 1990, Volume: 35, Issue:2

    Topics: Butylated Hydroxyanisole; Carcinogens; Catechol O-Methyltransferase; Coumarins; Cytochrome P-450 CYP

1990
[Teratogenic effect of coumarins].
    Zentralblatt fur Gynakologie, 1987, Volume: 109, Issue:6

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adult; Coumarins; Epiphyses; Female; Fetal Growt

1987
Coumarin induced acral skin necrosis associated with hereditary protein C deficiency.
    Blut, 1986, Volume: 52, Issue:6

    Topics: Adult; Antigen-Antibody Complex; Cesarean Section; Complement C4; Coumarins; Female; Glycoproteins;

1986
[Chondrodystrophia punctata--historical clinical review with special reference to chondrodysplasia punctata embryopathica].
    Beitrage zur Orthopadie und Traumatologie, 1985, Volume: 32, Issue:10

    Topics: Chondrodysplasia Punctata; Coumarins; Female; History, 17th Century; History, 18th Century; History,

1985