coumarin has been researched along with Malignant Melanoma in 7 studies
2H-chromen-2-one: coumarin derivative
| Excerpt | Relevance | Reference |
|---|---|---|
| "Both coumarin (1,2-benzopyrone) and warfarin (4-hydroxycoumarin) have been shown to prevent the recurrence of malignant melanoma." | 9.07 | Treatment with coumarin to prevent or delay recurrence of malignant melanoma. ( Breslin, B; Browne, H; Browne, HY; Corrigan, T; Daly, L; Daly, P; Edwards, G; Gaffney, E; Lynch, G; Thornes, RD, 1994) |
| "Coumarin (1,2-benzopyrone) as a daily oral dose of 50 mg was evaluated in a multicentre prospectively randomized, double-blind, placebo-controlled trial to prevent early recurrence of malignant melanoma TNM Stage IB (Breslow thickness greater than 1." | 9.06 | Prevention of early recurrence of high risk malignant melanoma by coumarin. Irish Melanoma Group. ( Browne, H; Corrigan, T; Daly, L; Daly, P; Edwards, G; Keane, F; Lynch, G; O'Loughlin, S; Tanner, A; Thornes, D, 1989) |
| "A375 melanoma cancer cells were used for testing cellular entry and anticancer potentials of HMC and nano-7-hydroxy-6-methoxy coumarin (NHMC) through several standard protocols." | 7.76 | Polymeric nanoparticle encapsulation of a naturally occurring plant scopoletin and its effects on human melanoma cell A375. ( Bhattacharyya, SS; Boujedaini, N; Khuda-Bukhsh, AR; Paul, S, 2010) |
| "Based on previous results demonstrating that coumarin and cimetidine render objective tumor regressions in renal cell carcinoma, we conducted a pilot study to determine whether these drugs possess activity against malignant melanoma." | 7.67 | Treatment of advanced malignant melanoma with coumarin and cimetidine: a pilot study. ( Butler, K; Cantrell, J; Marshall, ME; Mendelsohn, L; Wiseman, C, 1989) |
| "Immunostimulant therapy with coumarin and cimetidine was evaluated in 17 patients with advanced malignant melanoma." | 7.67 | Combined treatment of advanced malignant melanoma with coumarin and cimetidine. A phase II study. ( Langvad, E; Pedersen, L; Rose, C, 1987) |
| "Unlike other skin cancers, CM does not clearly correlate with exposure to ultraviolet radiation." | 5.35 | The increase in melanoma: are dietary furocoumarins responsible? ( Dowdy, JC; Sayre, RM, 2008) |
| "Both coumarin (1,2-benzopyrone) and warfarin (4-hydroxycoumarin) have been shown to prevent the recurrence of malignant melanoma." | 5.07 | Treatment with coumarin to prevent or delay recurrence of malignant melanoma. ( Breslin, B; Browne, H; Browne, HY; Corrigan, T; Daly, L; Daly, P; Edwards, G; Gaffney, E; Lynch, G; Thornes, RD, 1994) |
| "Coumarin (1,2-benzopyrone) as a daily oral dose of 50 mg was evaluated in a multicentre prospectively randomized, double-blind, placebo-controlled trial to prevent early recurrence of malignant melanoma TNM Stage IB (Breslow thickness greater than 1." | 5.06 | Prevention of early recurrence of high risk malignant melanoma by coumarin. Irish Melanoma Group. ( Browne, H; Corrigan, T; Daly, L; Daly, P; Edwards, G; Keane, F; Lynch, G; O'Loughlin, S; Tanner, A; Thornes, D, 1989) |
| "A375 melanoma cancer cells were used for testing cellular entry and anticancer potentials of HMC and nano-7-hydroxy-6-methoxy coumarin (NHMC) through several standard protocols." | 3.76 | Polymeric nanoparticle encapsulation of a naturally occurring plant scopoletin and its effects on human melanoma cell A375. ( Bhattacharyya, SS; Boujedaini, N; Khuda-Bukhsh, AR; Paul, S, 2010) |
| "Based on previous results demonstrating that coumarin and cimetidine render objective tumor regressions in renal cell carcinoma, we conducted a pilot study to determine whether these drugs possess activity against malignant melanoma." | 3.67 | Treatment of advanced malignant melanoma with coumarin and cimetidine: a pilot study. ( Butler, K; Cantrell, J; Marshall, ME; Mendelsohn, L; Wiseman, C, 1989) |
| "Immunostimulant therapy with coumarin and cimetidine was evaluated in 17 patients with advanced malignant melanoma." | 3.67 | Combined treatment of advanced malignant melanoma with coumarin and cimetidine. A phase II study. ( Langvad, E; Pedersen, L; Rose, C, 1987) |
| "Unlike other skin cancers, CM does not clearly correlate with exposure to ultraviolet radiation." | 1.35 | The increase in melanoma: are dietary furocoumarins responsible? ( Dowdy, JC; Sayre, RM, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khuda-Bukhsh, AR | 1 |
| Bhattacharyya, SS | 1 |
| Paul, S | 1 |
| Boujedaini, N | 1 |
| Sayre, RM | 1 |
| Dowdy, JC | 1 |
| Thornes, RD | 1 |
| Daly, L | 2 |
| Lynch, G | 2 |
| Breslin, B | 1 |
| Browne, H | 2 |
| Browne, HY | 1 |
| Corrigan, T | 2 |
| Daly, P | 2 |
| Edwards, G | 2 |
| Gaffney, E | 1 |
| Thornes, D | 1 |
| Tanner, A | 1 |
| Keane, F | 1 |
| O'Loughlin, S | 1 |
| Marshall, ME | 1 |
| Butler, K | 1 |
| Cantrell, J | 1 |
| Wiseman, C | 1 |
| Mendelsohn, L | 1 |
| Pedersen, L | 1 |
| Rose, C | 1 |
| Langvad, E | 1 |
2 trials available for coumarin and Malignant Melanoma
| Article | Year |
|---|---|
Treatment with coumarin to prevent or delay recurrence of malignant melanoma.
Topics: Chemotherapy, Adjuvant; Coumarins; Double-Blind Method; Female; Humans; Life Tables; Male; Melanoma; | 1994 |
Prevention of early recurrence of high risk malignant melanoma by coumarin. Irish Melanoma Group.
Topics: Adult; Combined Modality Therapy; Coumarins; Female; Humans; Male; Melanoma; Middle Aged; Multicente | 1989 |
5 other studies available for coumarin and Malignant Melanoma
| Article | Year |
|---|---|
Polymeric nanoparticle encapsulation of a naturally occurring plant scopoletin and its effects on human melanoma cell A375.
Topics: Apoptosis; Caspase 3; Coumarins; Down-Regulation; Humans; Imidazoles; Lactic Acid; Melanoma; Nanopar | 2010 |
The increase in melanoma: are dietary furocoumarins responsible?
Topics: Animals; Coumarins; Diet; Family Health; Furocoumarins; Humans; Light; Melanoma; Models, Biological; | 2008 |
2nd Proceedings of The International Society of Coumarin Investigators (ISCI). 1,2-Benzopyrone (Coumarin): update on mechanisms of action - Treatment of renal cell carcinoma and prostate cancer - Prevention of melanoma recurrence. Hamburg, Germany, 9 Marc
Topics: Animals; Antineoplastic Agents; Carcinoma, Renal Cell; Coumarins; Humans; Kidney Neoplasms; Male; Me | 1994 |
Treatment of advanced malignant melanoma with coumarin and cimetidine: a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cimetidine; Coumarin | 1989 |
Combined treatment of advanced malignant melanoma with coumarin and cimetidine. A phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cimetidine; Coumarins; Drug Evaluation; | 1987 |