coumarin has been researched along with Leukemia in 3 studies
2H-chromen-2-one: coumarin derivative
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The presumption that some coumarins might be lead compounds in the search for new differentiation agents against leukemia is based on the fact that natural coumarins, 5-(3-methyl-2-butenyloxy)-6,7-methylenedioxycoumarin (C-2) and 5-methoxy-6,7-methylenedioxycoumarin (C-1) inhibit proliferation and induce differentiation in U-937 cells [Riveiro, M." | 3.75 | Toward establishing structure-activity relationships for oxygenated coumarins as differentiation inducers of promonocytic leukemic cells. ( Davio, C; De Kimpe, N; Debenedetti, S; Jacobs, J; Maes, D; Mangelinckx, S; Riveiro, ME; Shayo, C; Vázquez, R; Vermeulen, M, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Riveiro, ME | 1 |
| Maes, D | 1 |
| Vázquez, R | 1 |
| Vermeulen, M | 1 |
| Mangelinckx, S | 1 |
| Jacobs, J | 1 |
| Debenedetti, S | 1 |
| Shayo, C | 1 |
| De Kimpe, N | 1 |
| Davio, C | 1 |
| DOUGLAS, AS | 1 |
| MAIR, K | 1 |
| HYNIE, J | 1 |
| CERMAK, L | 1 |
| GREGOR, O | 1 |
| POKORNY, J | 1 |
3 other studies available for coumarin and Leukemia
| Article | Year |
|---|---|
Toward establishing structure-activity relationships for oxygenated coumarins as differentiation inducers of promonocytic leukemic cells.
Topics: Antineoplastic Agents; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Coumarins; Humans | 2009 |
The Christmas factor deficiency in coumarin therapy.
Topics: Coumarins; Factor IX; Humans; Leukemia | 1958 |
[Anticoagulant therapy of priapism with pelentan in chronic myeloid leukemia].
Topics: Anticoagulants; Coumarins; Ethyl Biscoumacetate; Humans; Leukemia; Leukemia, Myelogenous, Chronic, B | 1952 |