coumarin has been researched along with Edema in 17 studies
2H-chromen-2-one: coumarin derivative
Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of the study was to explore the inhibition efficacy of new synthetic coumarinolignans (SCLs) against the secretion of pro-inflammatory cytokines in two in vivo models of inflammation." | 7.96 | New synthetic coumarinolignans as attenuators of pro-inflammatory cytokines in LPS-induced sepsis and carrageenan-induced paw oedema models. ( Araya, H; Begum Ahil, S; Fujimoto, Y; Hira, K; Kulkarni, OP; Kumar, SS, 2020) |
| "The dose-response relationship upon intraperitoneal administration of coumarin (C) and 7-hydroxycoumarin (7HC) in rats was evaluated using the carrageenan induced edema of the hind paw." | 7.66 | Investigation of the dose-response relationship upon intraperitoneal administration of coumarin and 7-hydroxycoumarin on the carrageenan induced edema of the rat hind paw. ( Hardt, TJ; Ritschel, WA, 1983) |
| "The aim of the study was to explore the inhibition efficacy of new synthetic coumarinolignans (SCLs) against the secretion of pro-inflammatory cytokines in two in vivo models of inflammation." | 3.96 | New synthetic coumarinolignans as attenuators of pro-inflammatory cytokines in LPS-induced sepsis and carrageenan-induced paw oedema models. ( Araya, H; Begum Ahil, S; Fujimoto, Y; Hira, K; Kulkarni, OP; Kumar, SS, 2020) |
| "The dose-response relationship upon intraperitoneal administration of coumarin (C) and 7-hydroxycoumarin (7HC) in rats was evaluated using the carrageenan induced edema of the hind paw." | 3.66 | Investigation of the dose-response relationship upon intraperitoneal administration of coumarin and 7-hydroxycoumarin on the carrageenan induced edema of the rat hind paw. ( Hardt, TJ; Ritschel, WA, 1983) |
| " No adverse events were recorded." | 2.90 | Effectiveness and safety of a mixture of diosmin, coumarin and arbutin (Linfadren ( Cacchio, A; De Blasis, E; Di Carlo, G; Vincenza, C, 2019) |
| "Coumarin is a secondary phytochemical with hepatotoxic and carcinogenic properties." | 2.46 | Toxicology and risk assessment of coumarin: focus on human data. ( Abraham, K; Heinemeyer, G; Lampen, A; Lindtner, O; Wöhrlin, F, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (29.41) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 5 (29.41) | 29.6817 |
| 2010's | 4 (23.53) | 24.3611 |
| 2020's | 2 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Kontogiorgis, CA | 2 |
| Hadjipavlou-Litina, DJ | 4 |
| Symeonidis, T | 1 |
| Chamilos, M | 1 |
| Kallitsakis, M | 1 |
| Litinas, KE | 1 |
| Kumar, SS | 1 |
| Hira, K | 1 |
| Begum Ahil, S | 1 |
| Kulkarni, OP | 1 |
| Araya, H | 1 |
| Fujimoto, Y | 1 |
| Alshibl, HM | 1 |
| Al-Abdullah, ES | 1 |
| Haiba, ME | 1 |
| Alkahtani, HM | 1 |
| Awad, GEA | 1 |
| Mahmoud, AH | 1 |
| Ibrahim, BMM | 1 |
| Bari, A | 1 |
| Villinger, A | 1 |
| Cacchio, A | 1 |
| Di Carlo, G | 1 |
| Vincenza, C | 1 |
| De Blasis, E | 1 |
| Belczak, SQ | 1 |
| Sincos, IR | 1 |
| Campos, W | 1 |
| Beserra, J | 1 |
| Nering, G | 1 |
| Aun, R | 1 |
| Melagraki, G | 1 |
| Afantitis, A | 1 |
| Igglessi-Markopoulou, O | 1 |
| Detsi, A | 1 |
| Koufaki, M | 1 |
| Kontogiorgis, C | 1 |
| Abraham, K | 1 |
| Wöhrlin, F | 1 |
| Lindtner, O | 1 |
| Heinemeyer, G | 1 |
| Lampen, A | 1 |
| Sashidhara, KV | 1 |
| Kumar, M | 1 |
| Modukuri, RK | 1 |
| Sonkar, R | 1 |
| Bhatia, G | 1 |
| Khanna, AK | 1 |
| Rai, S | 1 |
| Shukla, R | 1 |
| SZIRMAI, E | 2 |
| Hardt, TJ | 1 |
| Ritschel, WA | 1 |
| Miller, SH | 1 |
| Abell, M | 1 |
| Buck, D | 1 |
| Kress, D | 1 |
| Davis, TS | 1 |
| DeMuth, RJ | 1 |
| Gaffney, RM | 1 |
| Jörger, U | 1 |
| Ludwig, MM | 1 |
| Vahlensieck, M | 1 |
| Stumpe, KO | 1 |
| Clement, DL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized, Double-blind, Placebo-controlled Clinical Trial to Assess the Efficacy of µSmin® Plus (Dietary Supplement) in Chronic Venous Insufficiency Symptoms Relief[NCT04101201] | 73 participants (Actual) | Interventional | 2019-11-15 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for coumarin and Edema
| Article | Year |
|---|---|
Toxicology and risk assessment of coumarin: focus on human data.
Topics: Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Coumarins; Edema; Flavoring Agen | 2010 |
Management of venous edema: insights from an international task force.
Topics: Anticoagulants; Bandages; Calcium Dobesilate; Cardiovascular Agents; Chronic Disease; Controlled Cli | 2000 |
2 trials available for coumarin and Edema
| Article | Year |
|---|---|
Effectiveness and safety of a mixture of diosmin, coumarin and arbutin (Linfadren
Topics: Adult; Aged; Arbutin; Child; Combined Modality Therapy; Coumarins; Diosmin; Drug Combinations; Edema | 2019 |
Veno-active drugs for chronic venous disease: A randomized, double-blind, placebo-controlled parallel-design trial.
Topics: Biomechanical Phenomena; Brazil; Cardiovascular Agents; Chronic Disease; Coumarins; Diosmin; Double- | 2014 |
13 other studies available for coumarin and Edema
| Article | Year |
|---|---|
Synthesis and biological evaluation of novel coumarin derivatives with a 7-azomethine linkage.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Azo Compounds; Carrageenan; Coumarin | 2004 |
Synthesis and antiinflammatory activity of coumarin derivatives.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Coumarins; C | 2005 |
Synthesis of hydroxycoumarins and hydroxybenzo[f]- or [h]coumarins as lipid peroxidation inhibitors.
Topics: Animals; Antioxidants; Biphenyl Compounds; Combinatorial Chemistry Techniques; Coumarins; Edema; Lip | 2009 |
New synthetic coumarinolignans as attenuators of pro-inflammatory cytokines in LPS-induced sepsis and carrageenan-induced paw oedema models.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Coumarins; Cytokines; Disease Models, Animal; Edema; | 2020 |
Synthesis and Evaluation of New Coumarin Derivatives as Antioxidant, Antimicrobial, and Anti-Inflammatory Agents.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antioxidants; Coumarins; Edema; Formaldehy | 2020 |
Synthesis and evaluation of the antioxidant and anti-inflammatory activity of novel coumarin-3-aminoamides and their alpha-lipoic acid adducts.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Coumarins; Edema; Female; Glycine max; Lipoxygenase | 2009 |
Synthesis and anti-inflammatory activity of novel biscoumarin-chalcone hybrids.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chalcone; Coumarins; Edema; Microsomes; Rats | 2011 |
[Therapeutic and diuretic effects of dicumarin in hydrops gravidarum].
Topics: Coumarins; Diuretics; Edema; Female; Humans; Pregnancy | 1951 |
[The therapeutic and diuretic effect of dicoumarin in pregnancy dropsy].
Topics: Coumarins; Dicumarol; Diuretics; Edema; Female; Pregnancy; Pregnancy Complications | 1952 |
Investigation of the dose-response relationship upon intraperitoneal administration of coumarin and 7-hydroxycoumarin on the carrageenan induced edema of the rat hind paw.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Coumarins; Dose-Response Relationship, Drug; Edema; | 1983 |
Effects of 5,6 benzo-alphapyrone on traumatic edema due to crush and burn injury.
Topics: Animals; Burns; Coumarins; Edema; Hindlimb; Male; Organ Size; Rats | 1981 |
Resolution rates of artificially produced protein and amino acid oedemas and the effects of a benzopyrone.
Topics: Amino Acids; Animals; Blood Proteins; Coumarins; Edema; Male; Povidone; Rats; Rats, Inbred Strains; | 1981 |
Intermittent edema of the upper and lower extremities and the abdominal wall caused by membranous stenosis of the superior vena cava and membranous obstruction of the inferior vena cava.
Topics: Abdominal Muscles; Adult; Anticoagulants; Arm; Bandages; Clothing; Coumarins; Edema; Humans; Leg; Ma | 1996 |