coumarin has been researched along with Deficiency, Protein C in 14 studies
2H-chromen-2-one: coumarin derivative
| Excerpt | Relevance | Reference |
|---|---|---|
| "Coumarin-induced necrosis of the skin and subcutaneous tissue is an uncommon but well recognized complication of anticoagulant therapy." | 8.77 | Coumarin necrosis of the penis. ( Badalament, RA; Barkley, C; Drago, JR; Metz, EN; Nesbitt, J, 1989) |
| "Painful pink or magenta colored skin lesions characterized by a clear line of demarcation between the affected area and surrounding tissue appearing under therapy with coumarins may be a sign for evolving coumarin-necrosis." | 7.74 | [Impending Coumarin-necrosis in a patient with heterozygous protein C deficiency type I]. ( Behr, W; Ehret, W; Harwix, S; Murmann, K; Schlimok, G; Schulze, R; V Scheidt, W; Wittwer, H, 2008) |
| " Coumarin (warfarin)-induced skin necrosis is thought to be due to a rapid elimination of protein C relative to other vitamin K-dependent factors during the initial phase of oral anticoagulation." | 7.68 | Treatment of coumarin-induced skin necrosis with a monoclonal antibody purified protein C concentrate. ( Bauer, KA; Birkner, B; Linnau, Y; Rosenberg, RD; Schramm, W; Schwarz, HP; Spannagl, M, 1993) |
| "Defiency of protein C has been reported to be associated with recurrent thrombosis and pulmonary embolism, disseminated intravascular coagulation, and coumarin-induced skin necrosis and peripheral gangrene." | 7.67 | Recurrent thromboembolism, disseminated intravascular coagulation, and coumarin-induced skin necrosis associated with protein C deficiency. ( Lie, JT, 1988) |
| "On two occasions, an acquired functional protein C deficiency was present." | 5.27 | Recurrent coumarin-induced skin necrosis in a patient with an acquired functional protein C deficiency. ( Broekmans, AW; Loeliger, EA; Nienhuis, AM; Teepe, RG; Vermeer, BJ, 1986) |
| "Coumarin-induced necrosis of the skin and subcutaneous tissue is an uncommon but well recognized complication of anticoagulant therapy." | 4.77 | Coumarin necrosis of the penis. ( Badalament, RA; Barkley, C; Drago, JR; Metz, EN; Nesbitt, J, 1989) |
| "Painful pink or magenta colored skin lesions characterized by a clear line of demarcation between the affected area and surrounding tissue appearing under therapy with coumarins may be a sign for evolving coumarin-necrosis." | 3.74 | [Impending Coumarin-necrosis in a patient with heterozygous protein C deficiency type I]. ( Behr, W; Ehret, W; Harwix, S; Murmann, K; Schlimok, G; Schulze, R; V Scheidt, W; Wittwer, H, 2008) |
| " Coumarin-induced skin necrosis was a recurrent feature during oral anticoagulation therapy, forcing her physicians to treat her with nadroparin (Fraxiparin) for only a few months." | 3.72 | Late onset of clinical symptoms and recurrent ecchymotic skin lesions in a 12-year-old girl with a severe double heterozygous protein C deficiency. ( Alhenc-Gelas, M; Corazza, F; Demulder, A; Ferster, A; Loop, M, 2004) |
| " Coumarin (warfarin)-induced skin necrosis is thought to be due to a rapid elimination of protein C relative to other vitamin K-dependent factors during the initial phase of oral anticoagulation." | 3.68 | Treatment of coumarin-induced skin necrosis with a monoclonal antibody purified protein C concentrate. ( Bauer, KA; Birkner, B; Linnau, Y; Rosenberg, RD; Schramm, W; Schwarz, HP; Spannagl, M, 1993) |
| "Defiency of protein C has been reported to be associated with recurrent thrombosis and pulmonary embolism, disseminated intravascular coagulation, and coumarin-induced skin necrosis and peripheral gangrene." | 3.67 | Recurrent thromboembolism, disseminated intravascular coagulation, and coumarin-induced skin necrosis associated with protein C deficiency. ( Lie, JT, 1988) |
| "We present 2 cases of homozygous protein C deficiency with ocular and extraocular manifestation." | 1.30 | Ophthalmic manifestation of congenital protein C deficiency. ( Beeg, T; Hattenbach, LO; Kreuz, W; Zubcov, A, 1999) |
| "Subsequent to an infectious mononucleosis a 15 year old girl developed a thrombosis of the iliaca vein." | 1.29 | [Pelvic vein thrombosis in protein C deficiency after infectious mononucleosis]. ( Knees, U; Macdonald, E; Ohly, A; Pontz, BF; Stiegler, H, 1993) |
| "Skin necrosis associated with protein C deficiency has recently been reported to occur in hemodialysis patients." | 1.28 | Protein S deficiency and skin necrosis associated with continuous ambulatory peritoneal dialysis. ( Brubaker, R; Coots, MC; Glueck, HI; Kant, KS; Penn, I; Tonne, VA, 1992) |
| "On two occasions, an acquired functional protein C deficiency was present." | 1.27 | Recurrent coumarin-induced skin necrosis in a patient with an acquired functional protein C deficiency. ( Broekmans, AW; Loeliger, EA; Nienhuis, AM; Teepe, RG; Vermeer, BJ, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (28.57) | 18.7374 |
| 1990's | 8 (57.14) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Loop, M | 1 |
| Ferster, A | 1 |
| Corazza, F | 1 |
| Alhenc-Gelas, M | 1 |
| Demulder, A | 1 |
| Schulze, R | 1 |
| Behr, W | 1 |
| Wittwer, H | 1 |
| Harwix, S | 1 |
| Murmann, K | 1 |
| V Scheidt, W | 1 |
| Ehret, W | 1 |
| Schlimok, G | 1 |
| Griffin, JP | 1 |
| Knees, U | 1 |
| Macdonald, E | 1 |
| Stiegler, H | 1 |
| Ohly, A | 1 |
| Pontz, BF | 1 |
| Schramm, W | 1 |
| Spannagl, M | 1 |
| Bauer, KA | 2 |
| Rosenberg, RD | 1 |
| Birkner, B | 1 |
| Linnau, Y | 1 |
| Schwarz, HP | 1 |
| Hattenbach, LO | 1 |
| Beeg, T | 1 |
| Kreuz, W | 1 |
| Zubcov, A | 1 |
| van Heusden, AM | 1 |
| Merkus, HM | 1 |
| Dullemond-Westland, AC | 1 |
| Kant, KS | 1 |
| Glueck, HI | 1 |
| Coots, MC | 1 |
| Tonne, VA | 1 |
| Brubaker, R | 1 |
| Penn, I | 1 |
| Weiss, T | 1 |
| Diehm, C | 1 |
| Müller-Bühl, U | 1 |
| Schiffl, R | 1 |
| Wilhelm, C | 1 |
| Richter, GM | 1 |
| Barkley, C | 1 |
| Badalament, RA | 1 |
| Metz, EN | 1 |
| Nesbitt, J | 1 |
| Drago, JR | 1 |
| Kessler, CM | 1 |
| Strickland, DK | 1 |
| Lie, JT | 1 |
| Teepe, RG | 1 |
| Broekmans, AW | 1 |
| Vermeer, BJ | 1 |
| Nienhuis, AM | 1 |
| Loeliger, EA | 1 |
3 reviews available for coumarin and Deficiency, Protein C
| Article | Year |
|---|---|
Anticoagulants and skin necrosis.
Topics: Administration, Oral; Anticoagulants; Coumarins; Heparin; Humans; Necrosis; Protein C Deficiency; Pr | 1994 |
Coumarin necrosis of the penis.
Topics: Coumarins; Humans; Male; Middle Aged; Necrosis; Penis; Protein C Deficiency; Pulmonary Embolism | 1989 |
Protein C and protein S clinical perspectives.
Topics: Blood Coagulation Disorders; Coumarins; Deficiency Diseases; Glycoproteins; Humans; Protein C; Prote | 1987 |
11 other studies available for coumarin and Deficiency, Protein C
| Article | Year |
|---|---|
Late onset of clinical symptoms and recurrent ecchymotic skin lesions in a 12-year-old girl with a severe double heterozygous protein C deficiency.
Topics: Age of Onset; Anticoagulants; Child; Coumarins; DNA Mutational Analysis; Ecchymosis; Family Health; | 2004 |
[Impending Coumarin-necrosis in a patient with heterozygous protein C deficiency type I].
Topics: Adult; Anticoagulants; Coumarins; Female; Humans; Necrosis; Protein C; Protein C Deficiency | 2008 |
[Pelvic vein thrombosis in protein C deficiency after infectious mononucleosis].
Topics: Adolescent; Combined Modality Therapy; Coumarins; Drug Administration Schedule; Female; Heparin; Hum | 1993 |
Treatment of coumarin-induced skin necrosis with a monoclonal antibody purified protein C concentrate.
Topics: Aged; Coumarins; Female; Humans; Necrosis; Protein C; Protein C Deficiency; Skin | 1993 |
Coumarin-induced skin necrosis.
Topics: Aged; Coumarins; Female; Humans; Male; Middle Aged; Necrosis; Protein C; Protein C Deficiency; Skin | 1993 |
Ophthalmic manifestation of congenital protein C deficiency.
Topics: Anticoagulants; Cataract; Consanguinity; Coumarins; Eye Diseases; Female; Humans; IgA Vasculitis; In | 1999 |
Pregnancy and protein C deficiency.
Topics: Adult; Coumarins; Female; Fetal Death; Heparin; Humans; Pregnancy; Pregnancy Complications, Hematolo | 1992 |
Protein S deficiency and skin necrosis associated with continuous ambulatory peritoneal dialysis.
Topics: Blood Proteins; Coumarins; Female; Glycoproteins; Humans; Kidney Failure, Chronic; Middle Aged; Necr | 1992 |
[Thrombosis of the inferior vena cava in a 20-year-old patient with decreased protein C activity].
Topics: Adult; Coumarins; Female; Heparin; Humans; Phlebography; Protein C; Protein C Deficiency; Recurrence | 1990 |
Recurrent thromboembolism, disseminated intravascular coagulation, and coumarin-induced skin necrosis associated with protein C deficiency.
Topics: Adolescent; Blood Coagulation; Coumarins; Disseminated Intravascular Coagulation; Female; Gangrene; | 1988 |
Recurrent coumarin-induced skin necrosis in a patient with an acquired functional protein C deficiency.
Topics: Biopsy; Blood Coagulation Factors; Coumarins; Female; Humans; Middle Aged; Necrosis; Protein C Defic | 1986 |