coumarin has been researched along with Chronic Disease in 10 studies
2H-chromen-2-one: coumarin derivative
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Coumarin is not effective therapy for women who have lymphedema of the arm after treatment for breast cancer." | 9.09 | Lack of effect of coumarin in women with lymphedema after treatment for breast cancer. ( Kugler, JW; Levitt, R; Loprinzi, CL; Michalak, JC; Mowat, RB; Novotny, P; Quella, SK; Rooke, TW; Sloan, JA; Stella, PJ; Tschetter, LK; Windschitl, H, 1999) |
| " The present study examined intestinal anti-inflammatory activity of coumarin and its derivative, the 4-hydroxycoumarin on experimental ulcerative colitis in rats." | 7.74 | Intestinal anti-inflammatory activity of coumarin and 4-hydroxycoumarin in the trinitrobenzenesulphonic acid model of rat colitis. ( Cestari, SH; Di Stasi, LC; Luchini, AC; Pellizzon, CH; Rodrigues-Orsi, P; Seito, LN; Witaicenis, A, 2008) |
| "Coumarin is not effective therapy for women who have lymphedema of the arm after treatment for breast cancer." | 5.09 | Lack of effect of coumarin in women with lymphedema after treatment for breast cancer. ( Kugler, JW; Levitt, R; Loprinzi, CL; Michalak, JC; Mowat, RB; Novotny, P; Quella, SK; Rooke, TW; Sloan, JA; Stella, PJ; Tschetter, LK; Windschitl, H, 1999) |
| "We conducted a randomized, double-blind, placebo-controlled, crossover trial of 5,6-benzo-[alpha]-pyrone in 31 patients with postmastectomy lymphedema of the arm and 21 patients with lymphedema of the leg of various causes (this agent, also known as 56 BaP, 1,2-benzopyrone, or coumarin, is not an anticoagulant)." | 5.07 | Treatment of lymphedema of the arms and legs with 5,6-benzo-[alpha]-pyrone. ( Casley-Smith, JR; Morgan, RG; Piller, NB, 1993) |
| " The present study examined intestinal anti-inflammatory activity of coumarin and its derivative, the 4-hydroxycoumarin on experimental ulcerative colitis in rats." | 3.74 | Intestinal anti-inflammatory activity of coumarin and 4-hydroxycoumarin in the trinitrobenzenesulphonic acid model of rat colitis. ( Cestari, SH; Di Stasi, LC; Luchini, AC; Pellizzon, CH; Rodrigues-Orsi, P; Seito, LN; Witaicenis, A, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (30.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Belczak, SQ | 1 |
| Sincos, IR | 1 |
| Campos, W | 1 |
| Beserra, J | 1 |
| Nering, G | 1 |
| Aun, R | 1 |
| Luchini, AC | 1 |
| Rodrigues-Orsi, P | 1 |
| Cestari, SH | 1 |
| Seito, LN | 1 |
| Witaicenis, A | 1 |
| Pellizzon, CH | 1 |
| Di Stasi, LC | 1 |
| Krupa, M | 1 |
| Moskała, M | 1 |
| Składzień, T | 1 |
| Grzywna, E | 1 |
| THORSEN, G | 1 |
| WOOD, JC | 1 |
| CONN, HL | 1 |
| Casley-Smith, JR | 1 |
| Morgan, RG | 1 |
| Piller, NB | 2 |
| Chang, TS | 1 |
| Gan, JL | 1 |
| Fu, KD | 1 |
| Huang, WY | 1 |
| Loprinzi, CL | 1 |
| Kugler, JW | 1 |
| Sloan, JA | 1 |
| Rooke, TW | 1 |
| Quella, SK | 1 |
| Novotny, P | 1 |
| Mowat, RB | 1 |
| Michalak, JC | 1 |
| Stella, PJ | 1 |
| Levitt, R | 1 |
| Tschetter, LK | 1 |
| Windschitl, H | 1 |
| Clement, DL | 1 |
| Clodius, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized, Double-blind, Placebo-controlled Clinical Trial to Assess the Efficacy of µSmin® Plus (Dietary Supplement) in Chronic Venous Insufficiency Symptoms Relief[NCT04101201] | 73 participants (Actual) | Interventional | 2019-11-15 | Completed | |||
| Phase I Study Evaluating the Safety of Bevacizumab in Women With a History of Breast Cancer Suffering From Moderate to Severe Upper Extremity Lymphedema[NCT00318513] | Phase 1 | 35 participants | Interventional | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for coumarin and Chronic Disease
| Article | Year |
|---|---|
Management of venous edema: insights from an international task force.
Topics: Anticoagulants; Bandages; Calcium Dobesilate; Cardiovascular Agents; Chronic Disease; Controlled Cli | 2000 |
4 trials available for coumarin and Chronic Disease
| Article | Year |
|---|---|
Veno-active drugs for chronic venous disease: A randomized, double-blind, placebo-controlled parallel-design trial.
Topics: Biomechanical Phenomena; Brazil; Cardiovascular Agents; Chronic Disease; Coumarins; Diosmin; Double- | 2014 |
Treatment of lymphedema of the arms and legs with 5,6-benzo-[alpha]-pyrone.
Topics: Arm; Chronic Disease; Coumarins; Double-Blind Method; Female; Follow-Up Studies; Humans; Leg; Lymphe | 1993 |
The use of 5,6 benzo-[alpha]-pyrone (coumarin) and heating by microwaves in the treatment of chronic lymphedema of the legs.
Topics: Administration, Oral; Adult; Anticoagulants; Bandages; Chronic Disease; Combined Modality Therapy; C | 1996 |
Lack of effect of coumarin in women with lymphedema after treatment for breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Chronic Disease; Combined Modality Therapy; Coumar | 1999 |
5 other studies available for coumarin and Chronic Disease
| Article | Year |
|---|---|
Intestinal anti-inflammatory activity of coumarin and 4-hydroxycoumarin in the trinitrobenzenesulphonic acid model of rat colitis.
Topics: 4-Hydroxycoumarins; Acute Disease; Alkaline Phosphatase; Animals; Anti-Inflammatory Agents; Chronic | 2008 |
[Influence of anticoagulants on the appearance of chronic subdural hematoma].
Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Cardiovascular Diseases; Chronic Disease; C | 2009 |
Dicoumarol poisoning with relapse: report of a case.
Topics: Aged; Chronic Disease; Coumarins; Dicumarol; Humans; Recurrence | 1947 |
Prevention of systemic arterial embolism in chronic rheumatic heart disease by means of protracted anticoagulant therapy.
Topics: Anticoagulants; Chronic Disease; Coumarins; Embolism; Humans; Myocarditis; Rheumatic Heart Disease | 1954 |
The effect of coumarin (5,6 benzo-alpha-pyrone) on elicited members of the mononuclear system in dogs with chronic secondary lymphedema.
Topics: Animals; Chronic Disease; Coumarins; Dogs; Lymphedema; Monocytes; Phagocytosis | 1986 |