coumarin has been researched along with Adenocarcinoma in 8 studies
2H-chromen-2-one: coumarin derivative
Adenocarcinoma: A malignant epithelial tumor with a glandular organization.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 57-year-old male patient with advanced adenocarcinoma of the lung, who was administered oral anticoagulant therapy because of pulmonary embolism, developed coumarin necrosis confined to the penis and feet." | 8.80 | A case of coumarin necrosis with penile and pedal involvement. ( Baloğlu, H; Başak, M; Doğan, B; Harmanyeri, Y; Taşkapan, O, 1998) |
| "This results demonstrate that compound 8b induces caspase-dependent apoptosis as well as cytoprotective autophagy in lung adenocarcinoma cells, which may provide scientific evidence for developing this furoxan-based NO-releasing coumarin derivative as a potential anti-lung adenocarcinoma therapeutic agents." | 7.88 | A hybrid of coumarin and phenylsulfonylfuroxan induces caspase-dependent apoptosis and cytoprotective autophagy in lung adenocarcinoma cells. ( Chen, Y; Dong, M; Feng, M; Guo, Y; Jiang, S; Kuerban, K; Li, J; Wang, Q; Ye, L, 2018) |
| "Coumarin in vivo has antitumor activity in various types of cancer." | 5.31 | Decrease of cyclin D1 in the human lung adenocarcinoma cell line A-427 by 7-hydroxycoumarin. ( Elizalde-Galvan, P; García-Mondragón, MJ; Jiménez-Orozco, FA; León-Cedeño, F; López-González, JS; Mandoki, JJ; Mendoza-Patiño, N; Molina-Guarneros, JA; Nieto-Rodriguez, A; Velasco-Velázquez, MA, 2001) |
| "A 57-year-old male patient with advanced adenocarcinoma of the lung, who was administered oral anticoagulant therapy because of pulmonary embolism, developed coumarin necrosis confined to the penis and feet." | 4.80 | A case of coumarin necrosis with penile and pedal involvement. ( Baloğlu, H; Başak, M; Doğan, B; Harmanyeri, Y; Taşkapan, O, 1998) |
| "This results demonstrate that compound 8b induces caspase-dependent apoptosis as well as cytoprotective autophagy in lung adenocarcinoma cells, which may provide scientific evidence for developing this furoxan-based NO-releasing coumarin derivative as a potential anti-lung adenocarcinoma therapeutic agents." | 3.88 | A hybrid of coumarin and phenylsulfonylfuroxan induces caspase-dependent apoptosis and cytoprotective autophagy in lung adenocarcinoma cells. ( Chen, Y; Dong, M; Feng, M; Guo, Y; Jiang, S; Kuerban, K; Li, J; Wang, Q; Ye, L, 2018) |
| " Previously, the synthesis and cytotoxic activity on a human adenocarcinoma cell line of coumarin-, flavanon- and flavonol-derivatives of FAA were described." | 3.74 | The ability of coumarin-, flavanon- and flavonol-analogues of flavone acetic acid to stimulate human monocytes. ( Barbera, M; Bisi, A; Caputo, A; Carrara, M; Gobbi, S; Rampa, A; Zampiron, A, 2008) |
| "Coumarin in vivo has antitumor activity in various types of cancer." | 1.31 | Decrease of cyclin D1 in the human lung adenocarcinoma cell line A-427 by 7-hydroxycoumarin. ( Elizalde-Galvan, P; García-Mondragón, MJ; Jiménez-Orozco, FA; León-Cedeño, F; López-González, JS; Mandoki, JJ; Mendoza-Patiño, N; Molina-Guarneros, JA; Nieto-Rodriguez, A; Velasco-Velázquez, MA, 2001) |
| "Coumarin was also shown to possess antimetastatic activity in a Dunning R3327-MatLu tumour model." | 1.29 | Antitumour activity of coumarin in prostate and mammary cancer models. ( Kager, M; Maucher, A; von Angerer, E, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Q | 1 |
| Guo, Y | 1 |
| Jiang, S | 1 |
| Dong, M | 1 |
| Kuerban, K | 1 |
| Li, J | 1 |
| Feng, M | 1 |
| Chen, Y | 1 |
| Ye, L | 1 |
| Cruzan, G | 1 |
| Bus, J | 1 |
| Banton, M | 1 |
| Gingell, R | 1 |
| Carlson, G | 1 |
| Lopez-Gonzalez, JS | 2 |
| Prado-Garcia, H | 1 |
| Aguilar-Cazares, D | 1 |
| Molina-Guarneros, JA | 2 |
| Morales-Fuentes, J | 1 |
| Mandoki, JJ | 2 |
| Elinos-Báez, CM | 1 |
| León, F | 1 |
| Santos, E | 1 |
| Barbera, M | 1 |
| Caputo, A | 1 |
| Zampiron, A | 1 |
| Gobbi, S | 1 |
| Rampa, A | 1 |
| Bisi, A | 1 |
| Carrara, M | 1 |
| von Angerer, E | 1 |
| Kager, M | 1 |
| Maucher, A | 1 |
| Harmanyeri, Y | 1 |
| Taşkapan, O | 1 |
| Doğan, B | 1 |
| Baloğlu, H | 1 |
| Başak, M | 1 |
| Jiménez-Orozco, FA | 1 |
| Nieto-Rodriguez, A | 1 |
| Velasco-Velázquez, MA | 1 |
| Mendoza-Patiño, N | 1 |
| García-Mondragón, MJ | 1 |
| Elizalde-Galvan, P | 1 |
| León-Cedeño, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of 4-Methylumbelliferone for Treatment of Chronic Hepatitis B (HBV) and Chronic Hepatitis C (HCV)[NCT00225537] | Phase 2 | 160 participants | Interventional | 2005-09-30 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for coumarin and Adenocarcinoma
| Article | Year |
|---|---|
Mouse specific lung tumors from CYP2F2-mediated cytotoxic metabolism: an endpoint/toxic response where data from multiple chemicals converge to support a mode of action.
Topics: Adenocarcinoma; Adenoma; Animals; Bronchioles; Carcinogens; Cell Proliferation; Coumarins; Cytochrom | 2009 |
A case of coumarin necrosis with penile and pedal involvement.
Topics: Adenocarcinoma; Anticoagulants; Coumarins; Foot Dermatoses; Humans; Lung Neoplasms; Male; Middle Age | 1998 |
6 other studies available for coumarin and Adenocarcinoma
| Article | Year |
|---|---|
A hybrid of coumarin and phenylsulfonylfuroxan induces caspase-dependent apoptosis and cytoprotective autophagy in lung adenocarcinoma cells.
Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Apoptosis; Autophagy; Aut | 2018 |
Apoptosis and cell cycle disturbances induced by coumarin and 7-hydroxycoumarin on human lung carcinoma cell lines.
Topics: Adenocarcinoma; Annexin A5; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Carcin | 2004 |
Effects of coumarin and 7OH-coumarin on bcl-2 and Bax expression in two human lung cancer cell lines in vitro.
Topics: Adenocarcinoma; Antineoplastic Agents; bcl-2-Associated X Protein; Blotting, Western; Carcinoma, Squ | 2005 |
The ability of coumarin-, flavanon- and flavonol-analogues of flavone acetic acid to stimulate human monocytes.
Topics: Adenocarcinoma; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Coumarins; Drug Screeni | 2008 |
Antitumour activity of coumarin in prostate and mammary cancer models.
Topics: Adenocarcinoma; Animals; Coumarins; Disease Models, Animal; Female; Lung Neoplasms; Male; Mammary Ne | 1994 |
Decrease of cyclin D1 in the human lung adenocarcinoma cell line A-427 by 7-hydroxycoumarin.
Topics: Adenocarcinoma; Antineoplastic Agents; Biotransformation; Cell Cycle; Cell Division; Coumarins; Cycl | 2001 |