cortisol-succinate--sodium-salt and Syndrome

Thirteen cases of post-appendicectomy "fifth day syndrome" (0.45% of 2,919 children operated upon) are reported. The diagnosis must be established on precise criteria. Treatment is primarily medical, using antibiotics and anti-inflammatory drugs, and it must produce rapid and complete results. It is only when it fails (2 cases in our series) that a second operation is justified.

Topics: Anti-Bacterial Agents; Appendectomy; Child; Child, Preschool; Female; Humans; Hydrocortisone; Male; Peritonitis; Reoperation; Syndrome

Churg-Strauss vasculitis in remission for 4 1/2 years recurred, with new, previously undescribed features, after a lapse in corticosteroid therapy. Bilateral exophthalmos, unilateral hearing loss, and nasal obstruction accompanied fever, severe asthma, and palpable purpura. Leukocytosis with eosinophilia, an elevated ESR, hyperimmunoglobulinemia E, an pulmonary infiltrates were seen again. Circulating immune complexes were detected, and microamyloid deposits were found in the conjunctiva and skin. All clinical and laboratory manifestations responded to corticosteroid therapy. Monitoring the levels of IgE may add a diagnostic and prognostic feature to the classification of necrotizing vasculitides.

Topics: Adult; Amyloid; Antigen-Antibody Complex; Asthma; Exophthalmos; Female; Hearing Loss; Humans; Hydrocortisone; Immunoglobulin E; Nose Diseases; Polyarteritis Nodosa; Prednisone; Recurrence; Syndrome

Topics: Blood Transfusion; Chills; Fever; Hydrocortisone; Platelet Transfusion; Syndrome