cortisol-succinate--sodium-salt and Melanoma

cortisol-succinate--sodium-salt has been researched along with Melanoma* in 1 studies

Other Studies

1 other study(ies) available for cortisol-succinate--sodium-salt and Melanoma

Article	Year
Potentiation of photodynamic therapy with haematoporphyrin derivatives by glucocorticoids. Cancer letters, 1985, Volume: 29, Issue:1 The effect of glucocorticoids on tumour destruction by photodynamic therapy (PDT) with haematoporphyrin derivative (HPD) and light has been examined in a transplantable mouse tumour model. Administration of glucocorticoid after irradiation enhanced the effect of PDT on both Lewis lung carcinoma and B16 melanoma. Administration of methylprednisolone acetate in depot form concurrently with HPD inhibited the response to PDT while soluble hydrocortisone sodium succinate had no effect. Correctly timed administration of glucocorticoid may have a place in treatment of human tumours by PDT with HPD. Glucocorticoid did not reduce the temporary photosensitivity of the skin induced by HPD. Topics: Animals; Cell Line; Drug Interactions; Glucocorticoids; Hematoporphyrin Photoradiation; Hydrocortisone; Lung Neoplasms; Melanoma; Methylprednisolone; Methylprednisolone Acetate; Methylprednisolone Hemisuccinate; Mice; Mice, Inbred C57BL; Neoplasm Recurrence, Local; Photochemotherapy; Photosensitivity Disorders; Time Factors	1985

Article

Year

Potentiation of photodynamic therapy with haematoporphyrin derivatives by glucocorticoids.

Cancer letters, 1985, Volume: 29, Issue:1

The effect of glucocorticoids on tumour destruction by photodynamic therapy (PDT) with haematoporphyrin derivative (HPD) and light has been examined in a transplantable mouse tumour model. Administration of glucocorticoid after irradiation enhanced the effect of PDT on both Lewis lung carcinoma and B16 melanoma. Administration of methylprednisolone acetate in depot form concurrently with HPD inhibited the response to PDT while soluble hydrocortisone sodium succinate had no effect. Correctly timed administration of glucocorticoid may have a place in treatment of human tumours by PDT with HPD. Glucocorticoid did not reduce the temporary photosensitivity of the skin induced by HPD.

Topics: Animals; Cell Line; Drug Interactions; Glucocorticoids; Hematoporphyrin Photoradiation; Hydrocortisone; Lung Neoplasms; Melanoma; Methylprednisolone; Methylprednisolone Acetate; Methylprednisolone Hemisuccinate; Mice; Mice, Inbred C57BL; Neoplasm Recurrence, Local; Photochemotherapy; Photosensitivity Disorders; Time Factors

1985