Page last updated: 2024-11-06

corticosterone and Parkinson Disease

corticosterone has been researched along with Parkinson Disease in 12 studies

Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)

Research Excerpts

ExcerptRelevanceReference
"The primary motor symptoms of Parkinson's disease (PD) result from the degeneration of dopamine-producing neurons of the substantia nigra pars compacta (SNc), and often, the loss is asymmetrical, resulting in unilateral tremor presentation."1.62Characterizing the protracted neurobiological and neuroanatomical effects of paraquat in a murine model of Parkinson's disease. ( Ayoub, K; Beauchamp, S; Derksen, A; Dwyer, Z; Farmer, K; Fortin, T; Hayley, S; Rudyk, C; Shail, P; Torres, C; Ventura, K, 2021)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's1 (8.33)18.2507
2000's1 (8.33)29.6817
2010's8 (66.67)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Wang, Z1
Wu, J1
Yang, X2
Cai, P1
Liu, Q1
Wang, KDG1
Kong, L1
Wang, X1
Burtscher, J1
Copin, JC1
Rodrigues, J1
Kumar, ST1
Chiki, A1
Guillot de Suduiraut, I1
Sandi, C1
Lashuel, HA1
Dwyer, Z1
Rudyk, C1
Farmer, K1
Beauchamp, S1
Shail, P1
Derksen, A1
Fortin, T1
Ventura, K1
Torres, C1
Ayoub, K1
Hayley, S1
Hao, Y1
Shabanpoor, A1
Metz, GA1
Agnihotri, SK1
Sun, L1
Yee, BK1
Shen, R1
Akundi, RS1
Zhi, L1
Duncan, MJ1
Cass, WA1
Büeler, H1
Sugama, S1
Kakinuma, Y1
Wu, Q1
Zhang, Y1
Zhang, L1
Feng, L1
Engler, H1
Doenlen, R1
Riether, C1
Engler, A1
Niemi, MB1
Besedovsky, HO1
del Rey, A1
Pacheco-López, G1
Feldon, J1
Schedlowski, M1
Pålhagen, S1
Qi, H1
Mårtensson, B1
Wålinder, J1
Granérus, AK1
Svenningsson, P1
Gorton, LM1
Vuckovic, MG1
Vertelkina, N1
Petzinger, GM1
Jakowec, MW1
Wood, RI1
GILLHESPY, RO1
RATCLIFFE, AH1
Sawada, H1
Ibi, M1
Kihara, T1
Urushitani, M1
Akaike, A1
Shimohama, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Mindfulness-based Cognitive Therapy on Psychological Distress in People With Parkinson's Disease[NCT05779137]124 participants (Anticipated)Interventional2023-04-17Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

12 other studies available for corticosterone and Parkinson Disease

ArticleYear
Neuroprotective effects of benzyloxy substituted small molecule monoamine oxidase B inhibitors in Parkinson's disease.
    Bioorganic & medicinal chemistry, 2016, 11-15, Volume: 24, Issue:22

    Topics: Animals; Apoptosis; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Mice; Mice, Inbred S

2016
Chronic corticosterone aggravates behavioral and neuronal symptomatology in a mouse model of alpha-synuclein pathology.
    Neurobiology of aging, 2019, Volume: 83

    Topics: alpha-Synuclein; Animals; Behavior, Animal; Brain; Corticosterone; Disease Models, Animal; Dopaminer

2019
Characterizing the protracted neurobiological and neuroanatomical effects of paraquat in a murine model of Parkinson's disease.
    Neurobiology of aging, 2021, Volume: 100

    Topics: Age Factors; Animals; Antigens, Surface; Brain; Caspase 1; Corticosterone; Disease Models, Animal; D

2021
Stress and corticosterone alter synaptic plasticity in a rat model of Parkinson's disease.
    Neuroscience letters, 2017, 06-09, Volume: 651

    Topics: Adrenalectomy; Animals; Corticosterone; Disease Models, Animal; Dopamine; Male; Membrane Proteins; M

2017
PINK1 deficiency is associated with increased deficits of adult hippocampal neurogenesis and lowers the threshold for stress-induced depression in mice.
    Behavioural brain research, 2019, 05-02, Volume: 363

    Topics: Animals; Anxiety; Anxiety Disorders; Behavior, Animal; Cell Differentiation; Cell Proliferation; Cor

2019
Loss of dopaminergic neurons occurs in the ventral tegmental area and hypothalamus of rats following chronic stress: Possible pathogenetic loci for depression involved in Parkinson's disease.
    Neuroscience research, 2016, Volume: 111

    Topics: Animals; Corticosterone; Depression; Dopaminergic Neurons; Hypothalamus; Male; Microglia; Nerve Dege

2016
Chronic mild stress accelerates the progression of Parkinson's disease in A53T α-synuclein transgenic mice.
    Experimental neurology, 2016, Volume: 285, Issue:Pt A

    Topics: alpha-Synuclein; Animals; Body Weight; Case-Control Studies; Chromatography, High Pressure Liquid; C

2016
Time-dependent alterations of peripheral immune parameters after nigrostriatal dopamine depletion in a rat model of Parkinson's disease.
    Brain, behavior, and immunity, 2009, Volume: 23, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Cell Count; Corpus Striatum; Corticoste

2009
Monoamines, BDNF, IL-6 and corticosterone in CSF in patients with Parkinson's disease and major depression.
    Journal of neurology, 2010, Volume: 257, Issue:4

    Topics: Aged; Analysis of Variance; Biogenic Monoamines; Brain-Derived Neurotrophic Factor; Corticosterone;

2010
Exercise effects on motor and affective behavior and catecholamine neurochemistry in the MPTP-lesioned mouse.
    Behavioural brain research, 2010, Dec-01, Volume: 213, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Anxiety; Behavior, Animal; Brain; Corticoster

2010
Treatment of Parkinsonism with a new compound (B.S.5930).
    British medical journal, 1955, Aug-06, Volume: 2, Issue:4935

    Topics: Corticosterone; Diphenhydramine; Parkinson Disease; Parkinsonian Disorders

1955
Estradiol protects mesencephalic dopaminergic neurons from oxidative stress-induced neuronal death.
    Journal of neuroscience research, 1998, Dec-01, Volume: 54, Issue:5

    Topics: Animals; Cells, Cultured; Corticosterone; Dopamine; Estradiol; Estrogen Antagonists; Glutamic Acid;

1998