corticosterone has been researched along with Obesity in 322 studies
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Male rats of SL-water group presented on PND88: glucose intolerance, higher adiposity, plasma triglycerides, free fatty acids, total and low-density lipoprotein (LDL) cholesterol and corticosterone." | 8.12 | Lactation overnutrition-induced obesity impairs effects of exogenous corticosterone on energy homeostasis and hypothalamic-pituitary-adrenal axis in male rats. ( de Andrade, FG; de Souza, CF; Leite, CM; Lopes, GM; Martins, AB; Stopa, LRS; Uchoa, ET; Wunderlich, ALM; Zaia, CTBV; Zaia, DAM, 2022) |
| "Therefore ARC corticosterone, regulated by 11βHSD1, may play a role in food intake and body weight regulation." | 7.96 | Effects of corticosterone within the hypothalamic arcuate nucleus on food intake and body weight in male rats. ( Buckley, NW; Cai, M; Cheetham, S; Counsell, JR; Dhillo, WS; Farooq, G; Fernandes-Freitas, I; Gardiner, J; Izzi-Engbeaya, C; Ma, Y; Mirza, Z; Murphy, K; Norton, M; Ratnasabapathy, R; Richardson, E; Seckl, J, 2020) |
| " However, in VAT, GCs induce DNL, higher palmitic acid (PA), macrophage infiltration, and proinflammatory cytokine levels, accompanied by systemic nonesterified fatty acid (NEFA) elevation, hyperinsulinemia, and higher homeostatic model assessment for insulin resistance (HOMA-IR) levels compared with diet-induced obesity." | 7.96 | Long-term hypercortisolism induces lipogenesis promoting palmitic acid accumulation and inflammation in visceral adipose tissue compared with HFD-induced obesity. ( García-Eguren, G; Giró, O; Hanzu, FA; Sala-Vila, A; Vega-Beyhart, A, 2020) |
| "MCF7 breast cancer cells were incubated with increasing concentrations of corticosterone (CORT) to investigate the direct effects." | 7.81 | The direct and indirect effects of corticosterone and primary adipose tissue on MCF7 breast cancer cell cycle progression. ( Connor, MK; Riddell, MC; Shpilberg, Y, 2015) |
| " This study assessed the effects of the association between obesity and chronic stress on the temporal pattern of serum levels of adipogenic markers and corticosterone in rats." | 7.80 | Obesity and chronic stress are able to desynchronize the temporal pattern of serum levels of leptin and triglycerides. ( Caumo, W; Cioato, SG; de Macedo, IC; de Oliveira, C; de Oliveira, CM; de Souza, A; Marques Filho, PR; Medeiros, LF; Scarabelot, VL; Torres, IL, 2014) |
| "Although food-dependent energy intake was increased by telmisartan and telmisartan + ramipril compared with ramipril or controls, body weight gain, abundance of fat and plasma leptin levels were decreased." | 7.78 | Double blockade of angiotensin II (AT(1) )-receptors and ACE does not improve weight gain and glucose homeostasis better than single-drug treatments in obese rats. ( Jöhren, O; Miesel, A; Müller-Fielitz, H; Raasch, W; Vogt, FM, 2012) |
| " We recently developed a lentivirus (LV) vector that produces an insulin receptor (IR) antisense RNA sequence (IRAS) that when injected into the hypothalamus selectively decreases IR signaling in hypothalamus, resulting in increased body weight, peripheral adiposity and plasma leptin levels." | 7.77 | Obesity/hyperleptinemic phenotype adversely affects hippocampal plasticity: effects of dietary restriction. ( Evans, AN; Grillo, CA; Macht, VA; Mott, DD; Piroli, GG; Reagan, LP; Sakai, RR; Scott, KA; Wilson, SP, 2011) |
| "Chronic leptin treatment in diet-induced obese rats accelerates dietary obesity." | 7.74 | Synergy between leptin therapy and a seemingly negligible amount of voluntary wheel running prevents progression of dietary obesity in leptin-resistant rats. ( Cheng, KY; Matheny, M; Rogrigues, E; Scarpace, PJ; Shapiro, A; Tümer, N; Zhang, Y; Zolotukhin, S, 2008) |
| "Neuropeptide Y (NPY) stimulates feeding and weight gain, but deletion of the NPY gene does not affect food intake and body weight in mice bred on a mixed genetic background." | 7.73 | Neuropeptide Y deficiency attenuates responses to fasting and high-fat diet in obesity-prone mice. ( Ahima, RS; Elmquist, JK; Hawkins, EJ; Hileman, SM; Imai, Y; Patel, HR; Qi, Y, 2006) |
| " Oral administration of the Y1 antagonist (30 and 100 mg x kg(-1), once daily for 2 weeks) significantly suppressed the daily food intake and body weight gain in Zucker fatty rats accompanied with a reduction of fat cell size and plasma corticosterone levels." | 7.71 | Blockade of body weight gain and plasma corticosterone levels in Zucker fatty rats using an orally active neuropeptide Y Y1 antagonist. ( Fukami, T; Fukuroda, T; Gomori, A; Hata, M; Hidaka, M; Ihara, M; Ishihara, A; Ishii, Y; Kanatani, A; Kanesaka, M; Kanno, T; Kobayashi, M; Mashiko, S; Murai, T; Okada, M; Sato, NA; Tanaka, T; Tominaga, Y; Watanabe, K, 2002) |
| " The infusion abolished endogenous corticosterone output and produced hyperinsulinemia, hypertriglyceridemia, and hyperleptinemia, three salient abnormalities of obesity syndromes." | 7.70 | Induction of obesity and hyperleptinemia by central glucocorticoid infusion in the rat. ( Boss, O; Cusin, I; Jeanrenaud, B; Ricquier, D; Rohner-Jeanrenaud, F; Stricker-Krongrad, A; Zakrzewska, KE, 1999) |
| "To investigate whether chronic administration of the long-acting glucagon-like peptide-1 receptor agonist exendin-4 can elicit sustained reductions in food intake and body weight and whether its actions require an intact leptin system." | 7.70 | Central exendin-4 infusion reduces body weight without altering plasma leptin in (fa/fa) Zucker rats. ( Al-Barazanji, KA; Arch, JR; Buckingham, RE; Tadayyon, M, 2000) |
| "Neuropeptide Y (NPY) in the hypothalamus plays an important role in the regulation of food intake and body weight and seems to be implicated in the etiology of obesity." | 7.69 | Adrenalectomy prevents the obesity syndrome produced by chronic central neuropeptide Y infusion in normal rats. ( Cusin, I; Jeanrenaud, B; Rohner-Jeanrenaud, F; Sainsbury, A, 1997) |
| "We have investigated the possible involvement of endogenous corticosteroids in the maintenance of hypertension in aged lean and obese Zucker rats using the type II corticosteroid antagonist mifepristone." | 7.69 | Effects of the glucocorticoid II receptor antagonist mifepristone on hypertension in the obese Zucker rat. ( Clapham, JC; Turner, NC, 1997) |
| "The lethal yellow (AY/a) mouse has a defect in proopiomelanocortin (POMC) signaling in the brain that leads to obesity, and is resistant to the anorexigenic effects of the hormone leptin." | 7.69 | Independent and additive effects of central POMC and leptin pathways on murine obesity. ( Blaydon, KM; Boston, BA; Cone, RD; Varnerin, J, 1997) |
| "The effect of mifepristone (RU 486), a blocker of type II glucocorticoid receptors on the development of obesity that follows the feeding of a high-fat (HF) diet to Osborne-Mendel (OM) rats, has been investigated." | 7.68 | Mifepristone (RU 486), a blocker of type II glucocorticoid and progestin receptors, reverses a dietary form of obesity. ( Bray, GA; Okada, S; York, DA, 1992) |
| " NPY injected into the paraventricular nucleus and other regions causes hyperphagia, obesity, and increased secretion of insulin, glucagon, ACTH, and corticosterone." | 7.68 | Altered neuropeptide Y concentrations in specific hypothalamic regions of obese (fa/fa) Zucker rats. Possible relationship to obesity and neuroendocrine disturbances. ( Cotton, SJ; Holloway, B; Mayers, R; McCarthy, HD; McKibbin, PE; McMillan, S; Williams, G, 1991) |
| "Hair corticosterone was higher in HF mice than in CON (P<0." | 5.91 | High fat diet induces obesity, alters eating pattern and disrupts corticosterone circadian rhythms in female ICR mice. ( Casey, T; Fernández-Juricic, E; Gonzalez, M; Han-Hallett, Y; Rajput, P; Teeple, K, 2023) |
| "Corticosterone (CORT) was administered to mice for 8 weeks." | 5.72 | Corticosterone induces obesity partly ( Cao, L; Li, S; Li, T; Li, Y; Lu, J; Wang, G; Xu, T; Zhang, M, 2022) |
| "Obesity is a disease that has become a serious public health issue worldwide, and chronic stressors, which are a problem for modern society, cause neuroendocrine changes with alterations in food intake." | 5.38 | Cafeteria diet-induced obesity plus chronic stress alter serum leptin levels. ( Caumo, W; Cioato, SG; Macedo, IC; Medeiros, LF; Oliveira, C; Oliveira, CM; Rozisky, JR; Santos, VS; Scarabelot, VL; Silva, FR; Souza, A; Torres, IL, 2012) |
| "Leptin is a member of the IL-6 cytokine family and is primarily produced by adipose tissue." | 5.35 | Leptin acts in the periphery to protect thymocytes from glucocorticoid-mediated apoptosis in the absence of weight loss. ( Roberts, MR; Trotter-Mayo, RN, 2008) |
| "Obesity is an increasing socio-economic health problem." | 5.35 | Diet-induced obesity alters behavior as well as serum levels of corticosterone in F344 rats. ( Behrendt, P; Bode, FJ; Brabant, G; Buchenauer, T; Horn, R; Nave, H; Stephan, M, 2009) |
| "Leptin treatment of ob/ob mice markedly increased hepatic 11beta-HSD1 activity and mRNA expression." | 5.32 | Leptin activation of corticosterone production in hepatocytes may contribute to the reversal of obesity and hyperglycemia in leptin-deficient ob/ob mice. ( Friedman, TC; Li, R; Li, X; Liu, Y; Nakagawa, Y; Ohzeki, T; Wang, Y, 2003) |
| "Neuropeptide Y (NPY) is a powerful orexigenic neurotransmitter." | 5.32 | Chronic neuropeptide Y infusion into the lateral ventricle induces sustained feeding and obesity in mice lacking either Npy1r or Npy5r expression. ( Aubert, ML; Palmiter, RD; Pedrazzini, T; Raposinho, PD; White, RB, 2004) |
| "Male rats of SL-water group presented on PND88: glucose intolerance, higher adiposity, plasma triglycerides, free fatty acids, total and low-density lipoprotein (LDL) cholesterol and corticosterone." | 4.12 | Lactation overnutrition-induced obesity impairs effects of exogenous corticosterone on energy homeostasis and hypothalamic-pituitary-adrenal axis in male rats. ( de Andrade, FG; de Souza, CF; Leite, CM; Lopes, GM; Martins, AB; Stopa, LRS; Uchoa, ET; Wunderlich, ALM; Zaia, CTBV; Zaia, DAM, 2022) |
| " Metformin is shown to lower body weight and adiposity, but the underlying mechanism is unclear." | 4.02 | Metformin effectively restores the HPA axis function in diet-induced obese rats. ( Balasubramanian, P; Herdt, TH; MohanKumar, PS; MohanKumar, SMJ; Shin, AC; Suryadevara, P; Zyskowski, J, 2021) |
| "Carbonyl reductase 1 (Cbr1), a recently discovered contributor to tissue glucocorticoid metabolism converting corticosterone to 20β-dihydrocorticosterone (20β-DHB), is upregulated in adipose tissue of obese humans and mice and may contribute to cardiometabolic complications of obesity." | 4.02 | Carbonyl reductase 1 amplifies glucocorticoid action in adipose tissue and impairs glucose tolerance in lean mice. ( Allan, E; Beck, KR; Bell, RMB; Coutts, A; Denham, SG; Fawkes, A; Homer, NZM; Houtman, R; Koerner, MV; Lee, P; Meijer, OC; Miguelez-Crespo, A; Morgan, RA; Murphy, L; Nixon, M; Odermatt, A; Sharp, MGF; Villalobos, E; Walker, BR, 2021) |
| "Obesity and mild unmedicated metabolic risk factors alter the circulating steroid profile and bias the estimation of reference limits for testosterone, dihydrotestosterone, cortisol and corticosterone." | 3.96 | Impact of age, body weight and metabolic risk factors on steroid reference intervals in men. ( Baccini, M; Di Dalmazi, G; Fanelli, F; Fazzini, A; Gambineri, A; Mezzullo, M; Pagotto, U; Pelusi, C; Repaci, A; Vicennati, V, 2020) |
| "Therefore ARC corticosterone, regulated by 11βHSD1, may play a role in food intake and body weight regulation." | 3.96 | Effects of corticosterone within the hypothalamic arcuate nucleus on food intake and body weight in male rats. ( Buckley, NW; Cai, M; Cheetham, S; Counsell, JR; Dhillo, WS; Farooq, G; Fernandes-Freitas, I; Gardiner, J; Izzi-Engbeaya, C; Ma, Y; Mirza, Z; Murphy, K; Norton, M; Ratnasabapathy, R; Richardson, E; Seckl, J, 2020) |
| " However, in VAT, GCs induce DNL, higher palmitic acid (PA), macrophage infiltration, and proinflammatory cytokine levels, accompanied by systemic nonesterified fatty acid (NEFA) elevation, hyperinsulinemia, and higher homeostatic model assessment for insulin resistance (HOMA-IR) levels compared with diet-induced obesity." | 3.96 | Long-term hypercortisolism induces lipogenesis promoting palmitic acid accumulation and inflammation in visceral adipose tissue compared with HFD-induced obesity. ( García-Eguren, G; Giró, O; Hanzu, FA; Sala-Vila, A; Vega-Beyhart, A, 2020) |
| " Here we reported that long-term corticosterone (CORT) exposure in mice induced weight gain, dyslipidemia as well as hyperglycaemia and systemic insulin resistance." | 3.91 | Glucocorticoid-induced insulin resistance is related to macrophage visceral adipose tissue infiltration. ( Bruno, F; Do, TTH; Guillaume, D; Héloïse, D; Marie, G; Marion, B; Marthe, M, 2019) |
| " A murine model of corticosterone treatment resulted in increased hypothalamic expression of the melanocortin antagonist AgRP in parallel with obesity and hyperglycemia." | 3.91 | Metabolic Abnormalities of Chronic High-Dose Glucocorticoids Are Not Mediated by Hypothalamic AgRP in Male Mice. ( Adamson, A; Allen, TJ; Coll, AP; Davies, A; Harno, E; Humphreys, N; Sefton, C; Shoop, R; White, A; Wray, JR, 2019) |
| "Chronic corticosterone treatment led to insulin resistance, fasting hyperinsulinaemia, increased adiposity and dyslipidaemia in male, but not female mice." | 3.91 | Androgens sensitise mice to glucocorticoid-induced insulin resistance and fat accumulation. ( Cavanagh, LL; Gasparini, SJ; Henneicke, H; Kim, S; Seibel, MJ; Swarbrick, MM; Thai, LJ; Tu, J; Weber, MC; Zhou, H, 2019) |
| " In a mouse model for diet-induced obesity, rhythmicity of circulating corticosterone levels was disturbed." | 3.88 | Selective Glucocorticoid Receptor Antagonist CORT125281 Activates Brown Adipose Tissue and Alters Lipid Distribution in Male Mice. ( Hunt, H; Koorneef, LL; Kroon, J; Meijer, OC; Mol, IM; Rensen, PCN; Sips, HCM; van de Velde, NM; van den Heuvel, JK; Verzijl, CRC, 2018) |
| "Both treatments induced obesity but only Ob-MSG showed altered behavioral parameters, which is related to increased concentration of corticosterone and hypothalamic ERK1 and 2 activation." | 3.85 | Altered behavior of adult obese rats by monosodium l-glutamate neonatal treatment is related to hypercorticosteronemia and activation of hypothalamic ERK1 and ERK2. ( Andreazzi, AE; de Caires Júnior, LC; de Freitas Mathias, PC; Gonçalves, CF; González Garcia, RM; Guimarães, ED; Macedo de Almeida, M; Mourao-Júnior, CA; Musso, CM; Paes, ST; Pettersen, KG; Torrezan, R, 2017) |
| " Nine-month-old HF male offspring was normoglycemic but showed mild glucose intolerance, hyperinsulinemia, and hypercorticosteronemia." | 3.83 | Depot- and sex-specific effects of maternal obesity in offspring's adipose tissue. ( Breton, C; Deracinois, B; Eberlé, D; Gabory, A; Guinez, C; Junien, C; Laborie, C; Lecoutre, S; Lesage, J; Panchenko, PE; Vieau, D, 2016) |
| " Using a mouse model of excess corticosterone exposure, we found that the ability of glucocorticoids to increase adiposity, weight gain, hormonal dysregulation, hepatic steatosis, and dyslipidemia was reduced or reversed in mice lacking the cannabinoid CB1 receptor as well as mice treated with the global CB1 receptor antagonist AM251." | 3.81 | A peripheral endocannabinoid mechanism contributes to glucocorticoid-mediated metabolic syndrome. ( Bowles, NP; Hill, MN; Hillard, CJ; Karatsoreos, IN; Kunos, G; Li, X; Li, Z; Makriyannis, AM; McEwen, BS; Schwartz, GJ; Tamashiro, KL; Vemuri, VK; Wood, JA, 2015) |
| "MCF7 breast cancer cells were incubated with increasing concentrations of corticosterone (CORT) to investigate the direct effects." | 3.81 | The direct and indirect effects of corticosterone and primary adipose tissue on MCF7 breast cancer cell cycle progression. ( Connor, MK; Riddell, MC; Shpilberg, Y, 2015) |
| " We evaluated (1) the profile of basal circulating corticosterone across the life-course from weaning (postnatal day-PND 21), young adult PND 110, adult PND 450, mature adult PND 650 to aged phase PND 850 in a well-characterized homogeneous rat colony to determine existence of significant changes in trajectory in the second half of life; (2) sex differences; and (3) whether developmental programming of offspring by exposure to maternal obesity during development alters the later-life circulating corticosterone trajectory." | 3.81 | Aging, glucocorticoids and developmental programming. ( Nathanielsz, PW; Reyes-Castro, LA; Zambrano, E, 2015) |
| " This study assessed the effects of the association between obesity and chronic stress on the temporal pattern of serum levels of adipogenic markers and corticosterone in rats." | 3.80 | Obesity and chronic stress are able to desynchronize the temporal pattern of serum levels of leptin and triglycerides. ( Caumo, W; Cioato, SG; de Macedo, IC; de Oliveira, C; de Oliveira, CM; de Souza, A; Marques Filho, PR; Medeiros, LF; Scarabelot, VL; Torres, IL, 2014) |
| "Maternal phenotype during pregnancy and the end of lactation evidenced markedly elevated body fat and plasma corticosterone levels in HF dams." | 3.80 | Maternal obesity and high-fat diet program offspring metabolic syndrome. ( Beall, M; Desai, M; Han, G; Jellyman, JK; Lane, RH; Ross, MG, 2014) |
| "Hypothalamic inflammation is associated with insulin and leptin resistance, hyperphagia, and obesity." | 3.79 | Acute exercise suppresses hypothalamic PTP1B protein level and improves insulin and leptin signaling in obese rats. ( Carvalheira, JB; Chiarreotto-Ropelle, EC; Cintra, DE; de Souza, CT; Katashima, CK; Pauli, JR; Pauli, LS; Picardi, PK; Pimentel, GD; Prada, PO; Ropelle, ER; Silva, VR, 2013) |
| " At the end of the diet regimen, we assessed anxiety and depressive-like behaviour, corticosterone levels and biochemical changes in the midbrain and limbic brain regions." | 3.79 | Diet-induced obesity promotes depressive-like behaviour that is associated with neural adaptations in brain reward circuitry. ( Fulton, S; Sharma, S, 2013) |
| "Although food-dependent energy intake was increased by telmisartan and telmisartan + ramipril compared with ramipril or controls, body weight gain, abundance of fat and plasma leptin levels were decreased." | 3.78 | Double blockade of angiotensin II (AT(1) )-receptors and ACE does not improve weight gain and glucose homeostasis better than single-drug treatments in obese rats. ( Jöhren, O; Miesel, A; Müller-Fielitz, H; Raasch, W; Vogt, FM, 2012) |
| " Body weight remained elevated for more than 8 wk and was associated with elevated corticosterone and impaired glucose tolerance." | 3.78 | Hypothalamic Fkbp51 is induced by fasting, and elevated hypothalamic expression promotes obese phenotypes. ( Dunn-Meynell, A; Fan, X; Isoda, F; Janssen, W; Kleopoulos, SP; Levin, B; Mastaitis, J; McCrimmon, R; Mobbs, CV; Musatov, S; Sherwin, R; Yang, L; Yen, K, 2012) |
| " The main regulator of intracellular glucocorticoid levels are 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), which converts inactive glucocorticoid into bioactive glucocorticoid such as cortisol in humans and corticosterone in rodents; therefore, the inhibition of 11β-HSD1 has considerable therapeutic potential for metabolic diseases including obesity and diabetes." | 3.78 | Benzofuran derivatives inhibit 11β-hydroxysteroid dehydrogenase type 1 activity in rat adipose tissue. ( Kiyonaga, D; Kobayashi, Y; Kogure, T; Miyata, O; Tagawa, N; Ueda, M; Wakabayashi, M; Yamaguchi, Y, 2012) |
| " Insulin resistance and glucose intolerance were determined along with tissue glycogen content." | 3.78 | Carbenoxolone treatment ameliorated metabolic syndrome in WNIN/Ob obese rats, but induced severe fat loss and glucose intolerance in lean rats. ( Acharya, V; Ayyalasomayajula, V; Koppala, SR; Nemani, H; Ponday, LR; Pothana, S; Prasad Sakamuri, SS; Prathipati, VK; Putcha, UK; Sukapaka, M; Veetill, GN, 2012) |
| " We recently developed a lentivirus (LV) vector that produces an insulin receptor (IR) antisense RNA sequence (IRAS) that when injected into the hypothalamus selectively decreases IR signaling in hypothalamus, resulting in increased body weight, peripheral adiposity and plasma leptin levels." | 3.77 | Obesity/hyperleptinemic phenotype adversely affects hippocampal plasticity: effects of dietary restriction. ( Evans, AN; Grillo, CA; Macht, VA; Mott, DD; Piroli, GG; Reagan, LP; Sakai, RR; Scott, KA; Wilson, SP, 2011) |
| "Body weight and food intake in pregnancy, lactation, and after weaning, plasma leptin, insulin, corticosterone and blood glucose concentrations on days 7, 13 and 18 of pregnancy, days 1, 10, 21 and 80 postpartum, glucose and insulin tolerance on pregnancy days 7 and 18 were measured in C57Bl/6J mice of a/a (normal metabolism) and A(y)/a genotypes." | 3.76 | Pregnancy and lactation have anti-obesity and anti-diabetic effects in A(y)/a mice. ( Bazhan, NM; Makarova, EN; Shevchenko, AY; Yakovleva, TV, 2010) |
| " In this study, we examined both short- (24 d) and long- (16 wk) term effects of early postnatal over- and underfeeding in rats on body weight, body composition, plasma hormones, adiposity markers, and hypothalamic neuropeptide Y content." | 3.74 | Early undernutrition leads to long-lasting reductions in body weight and adiposity whereas increased intake increases cardiac fibrosis in male rats. ( Burrell, LM; Cole, TJ; Dean, RG; Morris, MJ; Velkoska, E, 2008) |
| "Chronic leptin treatment in diet-induced obese rats accelerates dietary obesity." | 3.74 | Synergy between leptin therapy and a seemingly negligible amount of voluntary wheel running prevents progression of dietary obesity in leptin-resistant rats. ( Cheng, KY; Matheny, M; Rogrigues, E; Scarpace, PJ; Shapiro, A; Tümer, N; Zhang, Y; Zolotukhin, S, 2008) |
| "MSG rats developed increased adrenocortical function, hyperadiposity, hyperleptinemia, hyperinsulinemia and decreased peripheral insulin sensitivity." | 3.73 | Impact of transient correction of increased adrenocortical activity in hypothalamo-damaged, hyperadipose female rats. ( Camihort, G; Console, G; Gaillard, RC; Luna, G; Moreno, G; Perelló, M; Spinedi, E, 2006) |
| " To investigate the possible mechanisms of antipsychotic-induced metabolic effects, we studied the impact of chronic administration of a typical antipsychotic drug (haloperidol) and an atypical antipsychotic (risperidone) to male rats on food intake, body weight, adiposity, and the circulating concentrations of hormones and metabolites that can influence energy homeostasis." | 3.73 | Distinct endocrine effects of chronic haloperidol or risperidone administration in male rats. ( Dedova, I; Duffy, L; Herzog, H; Karl, T; Lee, NJ; Lin, EJ; Matsumoto, I; O'brien, E; Sainsbury, A; Slack, K, 2006) |
| "Neuropeptide Y (NPY) stimulates feeding and weight gain, but deletion of the NPY gene does not affect food intake and body weight in mice bred on a mixed genetic background." | 3.73 | Neuropeptide Y deficiency attenuates responses to fasting and high-fat diet in obesity-prone mice. ( Ahima, RS; Elmquist, JK; Hawkins, EJ; Hileman, SM; Imai, Y; Patel, HR; Qi, Y, 2006) |
| " Concomitant with neuroendocrine defects such as decreased linear growth and infertility with accompanying increased corticosterone levels, this CNS knockout recapitulates the unique phenotype of db/db and ob/ob obese models and distinguishes them from other genetic models of obesity." | 3.72 | Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation. ( Fu, XY; Gao, Q; Horvath, TL; Morino, K; Neschen, S; Shulman, GI; Wolfgang, MJ, 2004) |
| " We investigated the effect of inhibition of 11beta-HSD with glycyrrhetinic acid (GE), an effective 11beta-HSD inhibitor, on body weight regulation in obese Zucker rats, which have a defect in the leptin receptor gene." | 3.72 | Different responsiveness in body weight and hepatic 11beta-hydroxysteroid dehydrogenase (11beta-HSD) type 1 mrna to 11beta-HSD inhibition by glycyrrhetinic acid treatment in obese and lean zucker rats. ( Fujisawa, Y; Li, RS; Nakagawa, Y; Nakanishi, T; Ohzeki, T, 2004) |
| "The higher CSF-to-serum leptin ratio in the S5B/P1 rats, the enhanced suppression of food intake and body weight with leptin injections, and the higher STAT-3 activity in these animals suggest that S5B/P1 rats are more sensitive to leptin than OM rats." | 3.72 | Effects of diet and time of the day on serum and CSF leptin levels in Osborne-Mendel and S5B/Pl rats. ( Bray, GA; Ishihara, Y; Kageyama, A; Kageyama, H; White, CL; York, DA, 2004) |
| " MTII delivered four times daily by intraperitoneal injection to C57BL/6J mice produced a dose-responsive effect on food intake, body weight, leptin, corticosterone, insulin, and free fatty acids." | 3.71 | Effects of acute and chronic administration of the melanocortin agonist MTII in mice with diet-induced obesity. ( Flier, JS; Mantzoros, CS; Moschos, S; Pierroz, DD; Ungsunan, L; Ziotopoulou, M, 2002) |
| " Oral administration of the Y1 antagonist (30 and 100 mg x kg(-1), once daily for 2 weeks) significantly suppressed the daily food intake and body weight gain in Zucker fatty rats accompanied with a reduction of fat cell size and plasma corticosterone levels." | 3.71 | Blockade of body weight gain and plasma corticosterone levels in Zucker fatty rats using an orally active neuropeptide Y Y1 antagonist. ( Fukami, T; Fukuroda, T; Gomori, A; Hata, M; Hidaka, M; Ihara, M; Ishihara, A; Ishii, Y; Kanatani, A; Kanesaka, M; Kanno, T; Kobayashi, M; Mashiko, S; Murai, T; Okada, M; Sato, NA; Tanaka, T; Tominaga, Y; Watanabe, K, 2002) |
| "Plasma leptin concentration is increased in hypertensive obese humans, but whether leptin contributes to the increased arterial pressure in obesity is not known." | 3.70 | Chronic leptin infusion increases arterial pressure. ( Brands, MW; Hall, JE; Shek, EW, 1998) |
| " These mice develop obesity that initially is due to decreased energy expenditure and later accompanied by hyperphagia despite increased levels of circulating leptin." | 3.70 | Severe leptin resistance in brown fat-deficient uncoupling protein promoter-driven diphtheria toxin A mice despite suppression of hypothalamic neuropeptide Y and circulating corticosterone concentrations. ( Flier, JS; Frederich, RC; Lowell, BB; Mantzoros, CS; Maratos-Flier, E; Qu, D, 1998) |
| "The present data indicate that testosterone plays a role in the development of obesity and NIDDM in young OLETF rats, but that changes of leptin production in white adipose tissue may not be important in the development of obesity in young OLETF rats." | 3.70 | Orchiectomy and response to testosterone in the development of obesity in young Otsuka-Long-Evans-Tokushima Fatty (OLETF) rats. ( Abe, Y; Ibuki, Y; Mori, M; Ohtani, KI; Sato, N; Shimizu, H; Takahashi, H; Tsuchiya, T; Uehara, Y, 1998) |
| " The infusion abolished endogenous corticosterone output and produced hyperinsulinemia, hypertriglyceridemia, and hyperleptinemia, three salient abnormalities of obesity syndromes." | 3.70 | Induction of obesity and hyperleptinemia by central glucocorticoid infusion in the rat. ( Boss, O; Cusin, I; Jeanrenaud, B; Ricquier, D; Rohner-Jeanrenaud, F; Stricker-Krongrad, A; Zakrzewska, KE, 1999) |
| " In both lean and obese rats, food deprivation led to a reduction in body weight that was accompanied by a reversible increase in plasma corticosterone levels." | 3.70 | Corticotropin-releasing hormone-binding protein in brain and pituitary of food-deprived obese (fa/fa) Zucker rats. ( Deshaies, Y; Picard, F; Richard, D; Timofeeva, E, 1999) |
| "To investigate whether chronic administration of the long-acting glucagon-like peptide-1 receptor agonist exendin-4 can elicit sustained reductions in food intake and body weight and whether its actions require an intact leptin system." | 3.70 | Central exendin-4 infusion reduces body weight without altering plasma leptin in (fa/fa) Zucker rats. ( Al-Barazanji, KA; Arch, JR; Buckingham, RE; Tadayyon, M, 2000) |
| " When administered to obese, hypercorticosteronemic Zucker rats, it causes a diminution of food intake and a reduction in their rate of weight gain." | 3.69 | The effect of DHEA given chronically to Zucker rats. ( Browne, E; Hilton, CW; Porter, JR; Svec, F; Wright, B, 1995) |
| "Neuropeptide Y (NPY) in the hypothalamus plays an important role in the regulation of food intake and body weight and seems to be implicated in the etiology of obesity." | 3.69 | Adrenalectomy prevents the obesity syndrome produced by chronic central neuropeptide Y infusion in normal rats. ( Cusin, I; Jeanrenaud, B; Rohner-Jeanrenaud, F; Sainsbury, A, 1997) |
| "The effect of fasting on hormonal and metabolic variables was evaluated in normal rats and in rats with obesity induced by neonatal treatment with monosodium glutamate (MSG)." | 3.69 | Hormonal and metabolic adaptations to fasting in monosodium glutamate-obese rats. ( Andrade, IS; do Nascimento, CM; Dolnikoff, MS; Hirata, AE; Ribeiro, EB, 1997) |
| "We have investigated the possible involvement of endogenous corticosteroids in the maintenance of hypertension in aged lean and obese Zucker rats using the type II corticosteroid antagonist mifepristone." | 3.69 | Effects of the glucocorticoid II receptor antagonist mifepristone on hypertension in the obese Zucker rat. ( Clapham, JC; Turner, NC, 1997) |
| "The lethal yellow (AY/a) mouse has a defect in proopiomelanocortin (POMC) signaling in the brain that leads to obesity, and is resistant to the anorexigenic effects of the hormone leptin." | 3.69 | Independent and additive effects of central POMC and leptin pathways on murine obesity. ( Blaydon, KM; Boston, BA; Cone, RD; Varnerin, J, 1997) |
| "We tested the hypothesis that hypercorticosteronemia causes the hypercholesterolemia in young developing "fatty" rats." | 3.68 | Is there a role for the adrenals in the development of hypercholesterolemia in Zucker fatty rats? ( Alarrayed, F; Hartman, AD; Porter, JR, 1992) |
| "The effect of mifepristone (RU 486), a blocker of type II glucocorticoid receptors on the development of obesity that follows the feeding of a high-fat (HF) diet to Osborne-Mendel (OM) rats, has been investigated." | 3.68 | Mifepristone (RU 486), a blocker of type II glucocorticoid and progestin receptors, reverses a dietary form of obesity. ( Bray, GA; Okada, S; York, DA, 1992) |
| " NPY injected into the paraventricular nucleus and other regions causes hyperphagia, obesity, and increased secretion of insulin, glucagon, ACTH, and corticosterone." | 3.68 | Altered neuropeptide Y concentrations in specific hypothalamic regions of obese (fa/fa) Zucker rats. Possible relationship to obesity and neuroendocrine disturbances. ( Cotton, SJ; Holloway, B; Mayers, R; McCarthy, HD; McKibbin, PE; McMillan, S; Williams, G, 1991) |
| "Whole brain concentrations of 3-hydroxybutyrate, glutamate and gamma-aminobutyric acid (GABA) have been measured in two strains of rats with differing susceptibility to obesity." | 3.67 | Brain 3-hydroxybutyrate, glutamate, and GABA in a rat model of dietary obesity. ( Bray, GA; Fisler, JS; Shimizu, H, 1989) |
| " To determine whether the return of hyperphagia was mediated by an action of the hormones on the central nervous system, food intake and body weight were monitored in anorexic GTG-treated obese adrenalectomized mice which received a single intracerebroventricular (icv) injection of very small amounts of adrenal glucocorticoids, including cortisone, corticosterone, and dexamethasone." | 3.67 | Central nervous system control of hyperphagia in hypothalamic obesity: dependence on adrenal glucocorticoids. ( Abrahamsen, S; Debons, AF; Tse, CS; Zurek, LD, 1986) |
| "Basal plasma levels of corticosterone and corticosteroid-binding globulin (CBG) have been investigated in Obese strain (OS) chickens afflicted with spontaneous autoimmune thyroiditis (SAT)." | 3.67 | Elevation of corticosteroid-binding globulin in obese strain (OS) chickens: possible implications for the disturbed immunoregulation and the development of spontaneous autoimmune thyroiditis. ( Fässler, R; Krömer, G; Schauenstein, K; Schwarz, S; Wick, G, 1986) |
| " The high corticosterone concentration in blood may account in part for development of obesity and other abnormalities in the ob/ob mouse." | 3.67 | Increased sensitivity of the genetically obese mouse to corticosterone. ( Himms-Hagen, J; Tokuyama, K, 1987) |
| "The contributions of insulin (IRI), glucagon (IRG), and corticosterone production to the glycemic changes associated with age and starvation were examined in 3 and 6 month old ob/ob and lean mice." | 3.66 | Starvation and age effects on glycoregulation and hormone levels of C57BL/6Job/ob mice. ( Cahn, PJ; Dubuc, PU; Ristimaki, S; Willis, PL, 1982) |
| "The relationship between obesity and influenza virus infection could be summarized by the following features: decreases in memory T-cell functionality and interferon (IFN)-α, IFN-β, and IFN-γ mRNA expression, increases in viral titer and infiltration, and impaired dendritic cell function in obese individuals." | 2.49 | Effect of adenovirus and influenza virus infection on obesity. ( Chun, SC; Hur, SJ; Kim, DH; Lee, SK, 2013) |
| "Obesity is associated with multiple alterations of the endocrine systems, including abnormal circulating blood hormone concentrations, due to changes in their pattern of secretion and/or metabolism, altered hormone transport, and/or action at the level of target tissues." | 2.41 | Adrenal and gonadal function in obesity. ( Gambineri, A; Pasquali, R; Vicennati, V, 2002) |
| "Although atherosclerosis was reduced in CD40AKO mice, plaques contained more activated T cells and larger necrotic cores." | 1.91 | Adipocytes control hematopoiesis and inflammation through CD40 signaling. ( Aarts, SABM; Atzler, D; Beckers, L; Bosmans, LA; Den Toom, M; Gijbels, MJJ; Kooijman, S; Lutgens, E; Poels, K; Reiche, ME; Rensen, PCN; Van Tiel, CM; Vos, WG; Weber, C, 2023) |
| " In line with this concept, chronic administration of a selective β3-AR agonist reproduced the beneficial metabolic effects of cold adaption during exposure to exogenous GCs." | 1.91 | Activation of β-adrenergic receptor signaling prevents glucocorticoid-induced obesity and adipose tissue dysfunction in male mice. ( Alexaki, VI; Baschant, U; Bornstein, SR; Dahl, A; Gado, M; Grafe, I; Heinrich, A; Henneicke, H; Hofbauer, LC; Perakakis, N; Rauner, M; Sameith, K; Swarbrick, MM; Wiedersich, D, 2023) |
| "Corticosterone levels were flattened by implanting mice with subcutaneous corticosterone-releasing pellets, resulting in constant circulating corticosterone levels." | 1.62 | A physiological glucocorticoid rhythm is an important regulator of brown adipose tissue function. ( Biermasz, NR; Fenzl, A; In Het Panhuis, W; Kiefer, FW; Kooijman, S; Koorneef, LL; Kroon, J; Meijer, OC; Mol, IM; Rensen, PCN; Schilperoort, M; Sips, HHCM; Tuckermann, JP; van den Berg, R; van den Heuvel, JK; van der Sluis, RJ; van Doeselaar, L; van Trigt, N; Verzijl, CRC; Vettorazzi, S, 2021) |
| "Overweight and obesity are a worldwide pandemic affecting billions of people." | 1.51 | Association of high-fat diet with neuroinflammation, anxiety-like defensive behavioral responses, and altered thermoregulatory responses in male rats. ( Abreu, AR; Campos, GSV; Chianca, DA; Chírico, MTT; De Menezes, RCA; Figueiredo, AB; Lima, PM; Lowry, CA; Noronha, SSR; Silva, FCS, 2019) |
| "In corticosterone-treated wild-type and UCP1 knockout mice housed at 30°C, obesity also develops to the same extent." | 1.51 | Glucocorticoid-Induced Obesity Develops Independently of UCP1. ( Boulet, N; Brooks, K; Cannon, B; Carlsson, B; Fischer, AW; Jaiprakash, A; Luijten, IHN; Nedergaard, J; Shabalina, IG, 2019) |
| " We hypothesized that surgically induced IUGR combined with an HFD would increase adiposity and glucocorticoids more than in non-IUGR offspring combined with the same HFD, findings that would persist despite weaning to a regular diet." | 1.48 | Intrauterine growth restriction combined with a maternal high-fat diet increased adiposity and serum corticosterone levels in adult rat offspring. ( Callaway, CW; McKnight, RA; Yu, B; Zinkhan, EK, 2018) |
| "Nonalcoholic fatty liver disease (NAFLD), a common prelude to cirrhosis and hepatocellular carcinoma, is the most common chronic liver disease worldwide." | 1.46 | Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling. ( Aronow, BJ; Cappelletti, M; Chan, CC; Divanovic, S; Giles, DA; Graspeuntner, S; Haslam, DB; Hogan, SP; Iwakura, Y; Kahn, CR; Karns, R; Karp, CL; Klarquist, J; Lawson, MJ; Moreno-Fernandez, ME; Mukherjee, R; Reynaud, D; Rupp, J; Shanmukhappa, SK; Sheridan, R; Sina, C; Softic, S; Stankiewicz, TE; Steinbrecher, KA; Stemmer, K; Sünderhauf, A; Wu, D, 2017) |
| "Weight gain was similar across the three diets while visceral fat mass was elevated by the two HFDs." | 1.46 | Saturated high-fat feeding independent of obesity alters hypothalamus-pituitary-adrenal axis function but not anxiety-like behaviour. ( Alquier, T; Daneault, C; Décarie-Spain, L; Fulton, S; Hryhorczuk, C; Rosiers, CD; Sharma, S, 2017) |
| "Obesity and type 2 diabetes have become a major public health problem worldwide." | 1.46 | Elevated Steroid Hormone Production in the db/db Mouse Model of Obesity and Type 2 Diabetes. ( Bornstein, SR; Brown, N; Brunssen, C; Eisenhofer, G; Frenzel, A; Hofmann, A; Jannasch, A; Mittag, J; Morawietz, H; Peitzsch, M; Weldon, SM, 2017) |
| "Obesity was established by cafeteria (CAF) feeding for 8 wk prior to mating and throughout pregnancy." | 1.43 | Obesity Disrupts the Rhythmic Profiles of Maternal and Fetal Progesterone in Rat Pregnancy. ( Clarke, MW; Crew, RC; Mark, PJ; Waddell, BJ, 2016) |
| " However, current glucocorticoid replacement regimes are inadequate because doses sufficient to suppress excess androgens almost invariably induce adverse metabolic effects." | 1.43 | ABCC1 confers tissue-specific sensitivity to cortisol versus corticosterone: A rationale for safer glucocorticoid replacement therapy. ( Andrew, R; Elfick, AP; Homer, NZ; Livingstone, DE; Mackenzie, SD; Mole, DJ; Morgan, RA; Mouras, R; Nixon, M; Reynolds, RM; Stimson, RH; Taylor, AI; Walker, BR, 2016) |
| "Obesity is a major risk factor for the development of type 2 diabetes and other debilitating diseases." | 1.42 | Changes in morphology and function of adrenal cortex in mice fed a high-fat diet. ( Bornstein, SR; Chavakis, T; Eaton, S; Eisenhofer, G; Lamounier-Zepter, V; Mateska, I; Peitzsch, M; Swierczynska, MM, 2015) |
| "Obesity is a chronic disease that has been associated with chronic stress and hypercaloric diet (HD) consumption." | 1.42 | Hypercaloric diet modulates effects of chronic stress: a behavioral and biometric study on rats. ( Caumo, W; de Macedo, IC; de Souza, IC; Filho, PR; Oliveira, Cd; Oliveira, CM; Quevedo, AS; Silva, FR; Torres, IL; Vercelino, R, 2015) |
| "Once obesity is established, DIO rats strongly defend their increased body weight against caloric restriction." | 1.40 | Regulation of expression of relaxin-3 and its receptor RXFP3 in the brain of diet-induced obese rats. ( Guèvremont, G; Lenglos, C; Mitra, A; Timofeeva, E, 2014) |
| "Behavioral modifications for the treatment of obesity, including caloric restriction, have notoriously low long-term success rates relative to bariatric weight-loss surgery." | 1.40 | Weight loss by calorie restriction versus bariatric surgery differentially regulates the hypothalamo-pituitary-adrenocortical axis in male rats. ( Benoit, SC; Egan, AE; Grayson, BE; Hakala-Finch, AP; Herman, JP; Kekulawala, M; Laub, H; Ressler, IB; Seeley, RJ; Ulrich-Lai, YM; Woods, SC, 2014) |
| "Nonalcoholic fatty liver disease (NAFLD) has been associated with glucocorticoid excess and androgen deficiency, yet in the majority of patients with steatohepatitis, circulating cortisol and androgen levels are normal." | 1.39 | Loss of 5α-reductase type 1 accelerates the development of hepatic steatosis but protects against hepatocellular carcinoma in male mice. ( Armstrong, MJ; Dowman, JK; Hopkins, LJ; Hübscher, SG; Lavery, GG; Morgan, SA; Nasiri, M; Newsome, PN; Nikolaou, N; Oprescu, A; Reynolds, GM; Tomlinson, JW; van Houten, EL; Visser, JA, 2013) |
| "Male obesity is associated with reduced sperm motility and morphology and increased sperm DNA damage and oxidative stress; however, the reversibility of these phenotypes has never been studied." | 1.38 | Diet and exercise in an obese mouse fed a high-fat diet improve metabolic health and reverse perturbed sperm function. ( Bakos, HW; Lane, M; Owens, JA; Palmer, NO; Setchell, BP, 2012) |
| "Obesity is a disease that has become a serious public health issue worldwide, and chronic stressors, which are a problem for modern society, cause neuroendocrine changes with alterations in food intake." | 1.38 | Cafeteria diet-induced obesity plus chronic stress alter serum leptin levels. ( Caumo, W; Cioato, SG; Macedo, IC; Medeiros, LF; Oliveira, C; Oliveira, CM; Rozisky, JR; Santos, VS; Scarabelot, VL; Silva, FR; Souza, A; Torres, IL, 2012) |
| "Metabolic syndrome is a condition that typically includes central obesity, insulin resistance, glucose intolerance, dyslipidemia, and hypertension." | 1.38 | Anatomic, hematologic, and biochemical features of C57BL/6NCrl mice maintained on chronic oral corticosterone. ( Cassano, AE; Karatsoreos, IN; Penraat, KA; Rasmussen, S; White, JR; Wilson, CD, 2012) |
| "Leptin is a member of the IL-6 cytokine family and is primarily produced by adipose tissue." | 1.35 | Leptin acts in the periphery to protect thymocytes from glucocorticoid-mediated apoptosis in the absence of weight loss. ( Roberts, MR; Trotter-Mayo, RN, 2008) |
| "Obesity is an increasing socio-economic health problem." | 1.35 | Diet-induced obesity alters behavior as well as serum levels of corticosterone in F344 rats. ( Behrendt, P; Bode, FJ; Brabant, G; Buchenauer, T; Horn, R; Nave, H; Stephan, M, 2009) |
| "Obesity is associated with a flattening of the diurnal rhythm; plasma cortisol levels are slightly increased during the trough, although they are normal or low in the morning." | 1.34 | Hippocampal 11beta-hydroxysteroid dehydrogenase type 1 messenger ribonucleic acid expression has a diurnal variability that is lost in the obese Zucker rat. ( Bergström, SA; Burén, J; Loh, E; Mattsson, C; Olsson, T; Söderström, I, 2007) |
| "Leptin treatment of ob/ob mice markedly increased hepatic 11beta-HSD1 activity and mRNA expression." | 1.32 | Leptin activation of corticosterone production in hepatocytes may contribute to the reversal of obesity and hyperglycemia in leptin-deficient ob/ob mice. ( Friedman, TC; Li, R; Li, X; Liu, Y; Nakagawa, Y; Ohzeki, T; Wang, Y, 2003) |
| "Neuropeptide Y (NPY) is a powerful orexigenic neurotransmitter." | 1.32 | Chronic neuropeptide Y infusion into the lateral ventricle induces sustained feeding and obesity in mice lacking either Npy1r or Npy5r expression. ( Aubert, ML; Palmiter, RD; Pedrazzini, T; Raposinho, PD; White, RB, 2004) |
| "Insulin sensitivity was assessed by means of an intravenous glucose tolerance test (IVGTT)." | 1.31 | Excess portal venous long-chain fatty acids induce syndrome X via HPA axis and sympathetic activation. ( Benthem, L; Keizer, K; Kuipers, F; Scheurink, AJ; Steffens, AB; Strubbe, JH; Wiegman, CH, 2000) |
| "Obesity has been associated with alterations in glucocorticoid metabolism in both man and rodents, but the underlying mechanisms remain undefined." | 1.31 | Mechanisms of dysregulation of 11 beta-hydroxysteroid dehydrogenase type 1 in obese Zucker rats. ( Kenyon, CJ; Livingstone, DE; Walker, BR, 2000) |
| "I3vt leptin caused an increase in plasma corticosterone and plasma leptin levels relative to the control condition." | 1.30 | Central leptin stimulates corticosterone secretion at the onset of the dark phase. ( Burn, P; Campfield, LA; Donahey, JC; Scheurink, AJ; Seeley, RJ; Steffens, AB; Tenenbaum, R; Thiele, TE; van Dijk, G; Wilkinson, CW; Woods, SC, 1997) |
| "Leptin treatment improved tolerance to an oral glucose load (16% reduction in the area under the blood glucose curve) while lowering plasma insulin." | 1.30 | Effects of intracerebroventricular infusion of leptin in obese Zucker rats. ( al-Barazanji, KA; Arch, JR; Buckingham, RE; Gloger, IS; Haynes, A; Holmes, SD; McBay, DL; McHale, MT; Mossakowska, DE; Wang, XM, 1997) |
| "Leptin treatment of obese mice significantly lowered LPL activity to that of lean mice in all tissues examined." | 1.30 | Effects of leptin adipose tissue lipoprotein lipase in the obese ob/ob mouse. ( Deshaies, Y; Huang, Q; Picard, F; Richard, D, 1998) |
| "Hyperglycemia was rapidly induced in Avy/a females by dexamethasone (dex)." | 1.29 | Dexamethasone-induced hyperglycemia in obese Avy/a (viable yellow) female mice entails preferential induction of a hepatic estrogen sulfotransferase. ( Chapman, HD; Gill, AM; Leiter, EH; Powell, JG; Yen, TT, 1994) |
| "Neuropeptide Y (NPY) is a 36 amino-acid peptide." | 1.29 | Hypothalamic neuropeptide Y messenger ribonucleic acid levels in pre-obese and genetically obese (fa/fa) rats; potential regulation thereof by corticotropin-releasing factor. ( Bchini-Hooft van Huijsduijnen, OB; Jeanrenaud, B; Rohner-Jeanrenaud, F, 1993) |
| "Mannoheptulose did not inhibit insulin secretion from control obese rats; however at concentrations of 1." | 1.29 | Effect of adrenalectomy on the development of a pancreatic islet lesion in fa/fa rats. ( Chan, CB; Kibenge, MT, 1996) |
| "Corticosterone infusion was more effective in suppressing portal CRF levels in adrenalectomized obese compared to adrenalectomized lean rats." | 1.28 | Hypothalamic-pituitary-adrenal axis function in the Zucker obese rat. ( Hauger, RL; Plotsky, PM; Thrivikraman, KV; Watts, AG, 1992) |
| "Metformin markedly reduced also the hyperinsulinemia of the obese animals without altering their plasma glucose or pancreatic insulin content which may reflect an improved insulin sensitivity after metformin treatment." | 1.28 | Subchronic treatment with metformin produces anorectic effect and reduces hyperinsulinemia in genetically obese Zucker rats. ( Huupponen, R; Koulu, M; Pesonen, U; Rouru, J, 1992) |
| "Mifepristone treatment resulted in a threefold increase in plasma corticosterone levels in lean Zucker rats, but it did not change corticosterone secretion in obese animals." | 1.28 | Differential hypothalamic arginine vasopressin response to glucocorticoid receptor antagonism in lean and obese Zucker rats. ( Huupponen, R; Jolkkonen, J; Koulu, M; Pesonen, U, 1992) |
| "Treatment with mifepristone for 4 days (10 mg/kg orally twice daily) significantly (P less than 0." | 1.28 | The glucocorticoid antagonist mifepristone reveals abnormal regulation of the adrenocortical system in obese Zucker rats. ( Heikinheimo, O; Huupponen, R; Koulu, M; Pesonen, U, 1992) |
| "The mifepristone treatment significantly increased plasma corticosterone levels in lean animals, but not in obese animals." | 1.28 | Effects of repeated administration of mifepristone and 8-OH-DPAT on expression of preproneuropeptide Y mRNA in the arcuate nucleus of obese Zucker rats. ( Huupponen, R; Koulu, M; Pesonen, U; Rouru, J, 1991) |
| "Corticosterone treatment induced a greater and earlier increase in mRNA levels in adrenalectomized obese rats than in adrenalectomized lean rats." | 1.28 | Adrenalectomy in the Zucker fatty rat: effect on m-RNA for malic enzyme and glyceraldehyde 3-phosphate dehydrogenase. ( Bray, GA; Hainault, I; Lavau, M; York, DA, 1991) |
| "Corticosterone treatment of adrenalectomized animals enhanced both basal and postabsorptive insulin levels, but adrenalectomized rats with VMH lesions were hyperinsulinemic compared with animals with sham lesions only under the postabsorptive condition." | 1.27 | Hypothalamic hyperinsulinemia and obesity: role of adrenal glucocorticoids. ( Banta, AR; Bruce, BK; Frohman, LA; King, BM; Tharel, GN, 1983) |
| "Corticosterone excretion was further suppressed to levels not different from those in lean rats after 2 days of dexamethasone (40 micrograms/kg X day)." | 1.27 | Hypercorticosteronuria and diminished pituitary responsiveness to corticotropin-releasing factor in obese Zucker rats. ( Bode, HH; Calles-Escandon, J; Carr, DB; Cunningham, JJ; Garrido, F, 1986) |
| "The naloxone-treated young, obese and non-obese SHR (controls) exhibited marked reduction of the weight of their pituitary and adrenal glands, whereas the pituitary and adrenal glands of naloxone-treated mature, obese and non-obese/SHR were greatly increased in weight." | 1.27 | Anti-opiate (naloxone) suppression of Cushingoid degenerative changes in obese/SHR. ( McMurtry, JP; Wexler, BC, 1985) |
| "Whereas obesity was associated with only moderate glucose intolerance and insulin resistance in A/J mice, obese C57BL/6J mice showed clear-cut diabetes with fasting blood glucose levels of greater than 240 mg/dl and blood insulin levels of greater than 150 microU/ml." | 1.27 | Diet-induced type II diabetes in C57BL/6J mice. ( Cochrane, C; Feinglos, MN; Kuhn, CM; McCubbin, JA; Surwit, RS, 1988) |
| "Corticosterone-treated obese rats had higher basal and glucose-stimulated insulin levels than similarly treated lean animals, although plasma glucose concentrations did not differ between phenotypes." | 1.27 | The parasympathetic nervous system and glucocorticoid-mediated hyperinsulinaemia in the genetically obese (fa/fa) Zucker rat. ( Fletcher, JM; McKenzie, N, 1988) |
| " The median effective concentration (EC50) and the maximal corticosterone response per microgram of DNA of dose-response curves derived from lean and obese rats were not significantly different." | 1.27 | Responsiveness of isolated adrenocortical cells from lean and obese Zucker rats to ACTH. ( Davenport, WD; Porter, JR; White, BD, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 69 (21.43) | 18.7374 |
| 1990's | 71 (22.05) | 18.2507 |
| 2000's | 72 (22.36) | 29.6817 |
| 2010's | 83 (25.78) | 24.3611 |
| 2020's | 27 (8.39) | 2.80 |
| Authors | Studies |
|---|---|
| Kelly, KP | 1 |
| Ellacott, KLJ | 1 |
| Chen, H | 1 |
| McGuinness, OP | 1 |
| Johnson, CH | 1 |
| de Souza, CF | 1 |
| Stopa, LRS | 1 |
| Martins, AB | 1 |
| Wunderlich, ALM | 1 |
| Lopes, GM | 1 |
| Zaia, DAM | 1 |
| Zaia, CTBV | 1 |
| de Andrade, FG | 1 |
| Leite, CM | 1 |
| Uchoa, ET | 1 |
| Morgan, SA | 2 |
| Gathercole, LL | 1 |
| Hassan-Smith, ZK | 1 |
| Tomlinson, J | 1 |
| Stewart, PM | 1 |
| Lavery, GG | 2 |
| Igual Gil, C | 1 |
| Coull, BM | 1 |
| Jonas, W | 1 |
| Lippert, RN | 1 |
| Klaus, S | 1 |
| Ost, M | 1 |
| Srivastava, RK | 1 |
| Ruiz de Azua, I | 1 |
| Conrad, A | 1 |
| Purrio, M | 1 |
| Lutz, B | 1 |
| Reiche, ME | 2 |
| Poels, K | 2 |
| Bosmans, LA | 2 |
| Vos, WG | 2 |
| Van Tiel, CM | 2 |
| Gijbels, MJJ | 2 |
| Aarts, SABM | 2 |
| Den Toom, M | 2 |
| Beckers, L | 2 |
| Weber, C | 2 |
| Atzler, D | 2 |
| Rensen, PCN | 4 |
| Kooijman, S | 3 |
| Lutgens, E | 2 |
| Teeple, K | 1 |
| Rajput, P | 1 |
| Gonzalez, M | 1 |
| Han-Hallett, Y | 1 |
| Fernández-Juricic, E | 1 |
| Casey, T | 1 |
| Martins, IP | 1 |
| Vargas, R | 1 |
| Saavedra, LPJ | 1 |
| Rickli, S | 1 |
| Matiusso, CCI | 1 |
| Pavanello, A | 2 |
| Casagrande, L | 1 |
| Pastre, MJ | 1 |
| Oliveira, JB | 1 |
| de Almeida, AM | 1 |
| de Souza, ACH | 1 |
| de Oliveira, JC | 1 |
| Malta, A | 2 |
| Mathias, PCF | 1 |
| Wang, G | 1 |
| Li, S | 1 |
| Li, Y | 1 |
| Zhang, M | 1 |
| Xu, T | 1 |
| Li, T | 1 |
| Cao, L | 2 |
| Lu, J | 1 |
| Yamazaki, H | 1 |
| Uehara, M | 1 |
| Yoshikawa, N | 1 |
| Kuribara-Souta, A | 1 |
| Yamamoto, M | 1 |
| Hirakawa, Y | 1 |
| Kabe, Y | 1 |
| Suematsu, M | 1 |
| Tanaka, H | 1 |
| Gado, M | 1 |
| Heinrich, A | 1 |
| Wiedersich, D | 1 |
| Sameith, K | 1 |
| Dahl, A | 1 |
| Alexaki, VI | 1 |
| Swarbrick, MM | 2 |
| Baschant, U | 1 |
| Grafe, I | 1 |
| Perakakis, N | 1 |
| Bornstein, SR | 3 |
| Rauner, M | 1 |
| Hofbauer, LC | 1 |
| Henneicke, H | 2 |
| Almehmadi, K | 1 |
| Fourman, S | 1 |
| Buesing, D | 1 |
| Ulrich-Lai, YM | 2 |
| Shahanoor, Z | 1 |
| Sultana, R | 1 |
| Savenkova, M | 1 |
| Karatsoreos, IN | 3 |
| Romeo, RD | 1 |
| Szalanczy, AM | 1 |
| Giorgio, G | 1 |
| Goff, E | 1 |
| Seshie, O | 1 |
| Grzybowski, M | 1 |
| Klotz, J | 1 |
| Geurts, AM | 1 |
| Redei, EE | 1 |
| Solberg Woods, LC | 1 |
| la Fleur, SE | 2 |
| Xu, J | 1 |
| Shao, X | 1 |
| Zeng, H | 1 |
| Wang, C | 1 |
| Li, J | 1 |
| Peng, X | 1 |
| Zhuo, Y | 1 |
| Hua, L | 1 |
| Meng, F | 1 |
| Han, X | 1 |
| Udagawa, H | 1 |
| Funahashi, N | 1 |
| Nishimura, W | 1 |
| Uebanso, T | 1 |
| Kawaguchi, M | 1 |
| Asahi, R | 1 |
| Nakajima, S | 1 |
| Nammo, T | 1 |
| Hiramoto, M | 1 |
| Yasuda, K | 1 |
| Tanaka, A | 1 |
| Takayama, K | 1 |
| Furubayashi, T | 1 |
| Mori, K | 1 |
| Takemura, Y | 1 |
| Amano, M | 1 |
| Maeda, C | 1 |
| Inoue, D | 1 |
| Kimura, S | 1 |
| Kiriyama, A | 1 |
| Katsumi, H | 1 |
| Miyazato, M | 1 |
| Kangawa, K | 1 |
| Sakane, T | 1 |
| Hayashi, Y | 1 |
| Yamamoto, A | 1 |
| Mezzullo, M | 1 |
| Di Dalmazi, G | 1 |
| Fazzini, A | 1 |
| Baccini, M | 1 |
| Repaci, A | 1 |
| Gambineri, A | 2 |
| Vicennati, V | 2 |
| Pelusi, C | 1 |
| Pagotto, U | 1 |
| Fanelli, F | 1 |
| Izzi-Engbeaya, C | 1 |
| Ma, Y | 1 |
| Buckley, NW | 1 |
| Ratnasabapathy, R | 1 |
| Richardson, E | 1 |
| Counsell, JR | 1 |
| Fernandes-Freitas, I | 1 |
| Norton, M | 1 |
| Farooq, G | 1 |
| Mirza, Z | 1 |
| Cai, M | 1 |
| Cheetham, S | 1 |
| Seckl, J | 1 |
| Murphy, K | 1 |
| Dhillo, WS | 1 |
| Gardiner, J | 1 |
| García-Eguren, G | 1 |
| Sala-Vila, A | 1 |
| Giró, O | 1 |
| Vega-Beyhart, A | 1 |
| Hanzu, FA | 1 |
| Bahlouli, W | 1 |
| Breton, J | 1 |
| Lelouard, M | 1 |
| L'Huillier, C | 1 |
| Tirelle, P | 1 |
| Salameh, E | 1 |
| Amamou, A | 1 |
| Atmani, K | 1 |
| Goichon, A | 1 |
| Bôle-Feysot, C | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Acute Response of Glucocorticoids Upon Food Intake[NCT04482738] | 36 participants (Actual) | Observational | 2020-05-14 | Completed | |||
| Meal-regulated Substrate Metabolism, Influence of Obesity and IL-6[NCT04687540] | 25 participants (Actual) | Interventional | 2021-04-09 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for corticosterone and Obesity
| Article | Year |
|---|---|
Effect of adenovirus and influenza virus infection on obesity.
Topics: Adenovirus Infections, Human; Animals; CD8-Positive T-Lymphocytes; Cell Differentiation; Corticoster | 2013 |
11β-Hydroxysteroid dehydrogenase type 1: relevance of its modulation in the pathophysiology of obesity, the metabolic syndrome and type 2 diabetes mellitus.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipose Tissue; Animals; Anti-Inflammatory Agents; Athe | 2012 |
Adrenal and gonadal function in obesity.
Topics: Adipose Tissue; Adrenal Glands; Animals; Corticosterone; Gonadal Steroid Hormones; Humans; Hydrocort | 2002 |
11beta-hydroxysteroid dehydrogenase type 1 and obesity.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adipose Ti | 2008 |
Insulin, corticosterone and the autonomic nervous system in animal obesities: a viewpoint.
Topics: Animals; Autonomic Nervous System; Cerebral Ventricles; Corticosterone; Insulin; Islets of Langerhan | 1995 |
[Chemical determination of adrenal cortex steroids and its significance for the medical diagnosis].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocortical Hyperfunction; Chemistry, Clinical; Corti | 1968 |
1 trial available for corticosterone and Obesity
| Article | Year |
|---|---|
[Influence of 6-dehydro-16-methylene-hydrocortisone on cortisol and corticosterone secretory rates, glucose tolerance and insulin level in adipose patients].
Topics: Corticosterone; Glucocorticoids; Glucose Tolerance Test; Humans; Hydrocortisone; Insulin; Obesity; P | 1971 |
315 other studies available for corticosterone and Obesity
| Article | Year |
|---|---|
Time-optimized feeding is beneficial without enforced fasting.
Topics: Animals; Circadian Clocks; Circadian Rhythm; Corticosterone; Diet, High-Fat; Energy Metabolism; Fast | 2021 |
Lactation overnutrition-induced obesity impairs effects of exogenous corticosterone on energy homeostasis and hypothalamic-pituitary-adrenal axis in male rats.
Topics: Animals; Corticosterone; Corticotropin-Releasing Hormone; Female; Glucocorticoids; Glucose Intoleran | 2022 |
11β-HSD1 contributes to age-related metabolic decline in male mice.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Corticosterone; Diabetes Mellitus, Type 2; Glu | 2022 |
Mitochondrial stress-induced GFRAL signaling controls diurnal food intake and anxiety-like behavior.
Topics: Anxiety; Corticosterone; Corticotropin-Releasing Hormone; Eating; Female; Glial Cell Line-Derived Ne | 2022 |
Cannabinoid CB1 Receptor Deletion from Catecholaminergic Neurons Protects from Diet-Induced Obesity.
Topics: Animals; Cannabinoids; Corticosterone; Diet, High-Fat; Dopamine beta-Hydroxylase; Endocannabinoids; | 2022 |
Adipocytes control hematopoiesis and inflammation through CD40 signaling.
Topics: Adipocytes; Animals; Atherosclerosis; Cardiovascular Diseases; CD40 Antigens; CD40 Ligand; Corticost | 2023 |
Adipocytes control hematopoiesis and inflammation through CD40 signaling.
Topics: Adipocytes; Animals; Atherosclerosis; Cardiovascular Diseases; CD40 Antigens; CD40 Ligand; Corticost | 2023 |
Adipocytes control hematopoiesis and inflammation through CD40 signaling.
Topics: Adipocytes; Animals; Atherosclerosis; Cardiovascular Diseases; CD40 Antigens; CD40 Ligand; Corticost | 2023 |
Adipocytes control hematopoiesis and inflammation through CD40 signaling.
Topics: Adipocytes; Animals; Atherosclerosis; Cardiovascular Diseases; CD40 Antigens; CD40 Ligand; Corticost | 2023 |
High fat diet induces obesity, alters eating pattern and disrupts corticosterone circadian rhythms in female ICR mice.
Topics: Animals; Circadian Rhythm; Corticosterone; Diet; Diet, High-Fat; Eating; Feeding Behavior; Female; M | 2023 |
Protein-caloric restriction induced HPA axis activation and altered the milk composition imprint metabolism of weaned rat offspring.
Topics: Adipose Tissue, Brown; Animals; Caloric Restriction; Corticosterone; Female; Humans; Hypothalamo-Hyp | 2023 |
Corticosterone induces obesity partly
Topics: Animals; Cell Proliferation; Corticosterone; Glucocorticoids; Intestines; Mice; Obesity | 2022 |
The crucial role of muscle glucocorticoid signaling in accelerating obesity and glucose intolerance via hyperinsulinemia.
Topics: Animals; Corticosterone; Diabetes Mellitus; Glucocorticoids; Glucose Intolerance; Hyperinsulinism; M | 2023 |
Activation of β-adrenergic receptor signaling prevents glucocorticoid-induced obesity and adipose tissue dysfunction in male mice.
Topics: Adipose Tissue; Adipose Tissue, Brown; Adipose Tissue, White; Animals; Corticosterone; Follow-Up Stu | 2023 |
Western diet-induced obesity interferes with the HPA axis-blunting effects of palatable food in male rats.
Topics: Animals; Body Weight; Corticosterone; Diet, Western; Hypothalamo-Hypophyseal System; Male; Obesity; | 2023 |
Metabolic dysfunctions following chronic oral corticosterone are modified by adolescence and sex in mice.
Topics: Adiposity; Animals; Corticosterone; Female; Glucocorticoids; Male; Mice; Obesity; Weight Gain | 2023 |
Changes in environmental stress over COVID-19 pandemic likely contributed to failure to replicate adiposity phenotype associated with
Topics: Adiposity; Animals; Communicable Disease Control; Corticosterone; COVID-19; Diet, High-Fat; Female; | 2023 |
Stress, rhythm, choice and the munchies - tribute to Mary F. Dallman.
Topics: Adiposity; Corticosterone; Female; Humans; Hypothalamo-Hypophyseal System; Obesity; Pituitary-Adrena | 2023 |
Hepatic-Specific FGF21 Knockout Abrogates Ovariectomy-Induced Obesity by Reversing Corticosterone Production.
Topics: Animals; Corticosterone; Diet, High-Fat; Estrogens; Female; Fibroblast Growth Factors; Glucocorticoi | 2023 |
Glucocorticoid receptor-NECAB1 axis can negatively regulate insulin secretion in pancreatic β-cells.
Topics: Animals; Chromatography, Liquid; Corticosterone; Glucose; Hydrocortisone; Insulin; Insulin Secretion | 2023 |
Transnasal Delivery of the Peptide Agonist Specific to Neuromedin-U Receptor 2 to the Brain for the Treatment of Obesity.
Topics: Administration, Intranasal; Animals; Anti-Obesity Agents; Brain; Corticosterone; HEK293 Cells; Human | 2020 |
Impact of age, body weight and metabolic risk factors on steroid reference intervals in men.
Topics: 17-alpha-Hydroxyprogesterone; Age Factors; Androstenedione; Body Mass Index; Body Weight; Chromatogr | 2020 |
Effects of corticosterone within the hypothalamic arcuate nucleus on food intake and body weight in male rats.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipose Tissue, Brown; Animals; Arcuate Nucleus of Hypo | 2020 |
Long-term hypercortisolism induces lipogenesis promoting palmitic acid accumulation and inflammation in visceral adipose tissue compared with HFD-induced obesity.
Topics: Animals; Corticosterone; Cushing Syndrome; Cytokines; Diet, High-Fat; Fatty Acids; Fatty Acids, None | 2020 |
Stress-induced intestinal barrier dysfunction is exacerbated during diet-induced obesity.
Topics: Animals; Cecum; Colon; Corticosterone; Diet, High-Fat; Gastrointestinal Microbiome; Humans; Hypoglyc | 2020 |
Metformin effectively restores the HPA axis function in diet-induced obese rats.
Topics: Animals; Body Weight; Corticosterone; Diet, High-Fat; Hypothalamo-Hypophyseal System; Male; Metformi | 2021 |
Sex-specific effects of ketogenic diet after pre-exposure to a high-fat, high-sugar diet in rats.
Topics: 3-Hydroxybutyric Acid; Adiposity; Animals; Biomarkers; Blood Glucose; Corticosterone; Diet, High-Fat | 2021 |
A physiological glucocorticoid rhythm is an important regulator of brown adipose tissue function.
Topics: Adipocytes; Adipose Tissue, Brown; Adiposity; Animals; Circadian Rhythm; Corticosterone; Fatty Acids | 2021 |
Carbonyl reductase 1 amplifies glucocorticoid action in adipose tissue and impairs glucose tolerance in lean mice.
Topics: Adipose Tissue; Alcohol Oxidoreductases; Animals; Corticosterone; Diet, High-Fat; Disease Models, An | 2021 |
Ghrelin receptor signaling is not required for glucocorticoid-induced obesity in female mice.
Topics: Adiposity; Animals; Antimicrobial Cationic Peptides; Behavior, Animal; Corticosterone; Eating; Femal | 2021 |
A Selective Bombesin Receptor Subtype 3 Agonist Promotes Weight Loss in Male Diet-Induced-Obese Rats With Circadian Rhythm Change.
Topics: Animals; Anti-Obesity Agents; Body Weight; Circadian Rhythm; Corticosterone; Diet, High-Fat; Energy | 2017 |
Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling.
Topics: Animals; Cold Temperature; Corticosterone; Diet, High-Fat; Disease Models, Animal; Disease Progressi | 2017 |
Saturated high-fat feeding independent of obesity alters hypothalamus-pituitary-adrenal axis function but not anxiety-like behaviour.
Topics: Animals; Anxiety; Anxiety Disorders; Body Weight; Corticosterone; Corticotropin-Releasing Hormone; D | 2017 |
Curcumin limits weight gain, adipose tissue growth, and glucose intolerance following the cessation of exercise and caloric restriction in rats.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipose Tissue; Animals; Caloric Restriction; Corticost | 2017 |
Selective Glucocorticoid Receptor Antagonist CORT125281 Activates Brown Adipose Tissue and Alters Lipid Distribution in Male Mice.
Topics: Adipocytes, Brown; Adiposity; Adrenal Glands; Animals; Anti-Obesity Agents; Cells, Cultured; Cortico | 2018 |
Intrauterine growth restriction combined with a maternal high-fat diet increased adiposity and serum corticosterone levels in adult rat offspring.
Topics: Adiposity; Animals; Animals, Newborn; Body Weight; Corticosterone; Diet, High-Fat; Female; Fetal Gro | 2018 |
Stress Response to Physical Exercise in Rats with Alimentary Obesity.
Topics: Animals; Body Weight; Corticosterone; Fatty Acids, Nonesterified; Male; Obesity; Organ Size; Physica | 2018 |
Both oophorectomy and obesity impaired solely hippocampal-dependent memory via increased hippocampal dysfunction.
Topics: Animals; Cognition; Corticosterone; Diet, High-Fat; Estrogens; Female; Hippocampus; Insulin Resistan | 2018 |
Glucocorticoid-induced insulin resistance is related to macrophage visceral adipose tissue infiltration.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipocytes; Adipose Tissue; Animals; Carbohydrate Dehyd | 2019 |
Mif deficiency promotes adiposity in fructose-fed mice.
Topics: Adipocytes; Adipose Tissue; Adiposity; Animals; Corticosterone; Fructose; Gene Expression Regulation | 2019 |
A miR-29a-driven negative feedback loop regulates peripheral glucocorticoid receptor signaling.
Topics: Adipocytes; Adipogenesis; Animals; Corticosterone; Feedback, Physiological; Female; Gene Expression | 2019 |
Metabolic Abnormalities of Chronic High-Dose Glucocorticoids Are Not Mediated by Hypothalamic AgRP in Male Mice.
Topics: Adipose Tissue; Agouti-Related Protein; Animals; Body Weight; Corticosterone; Eating; Gene Expressio | 2019 |
Responsiveness of hypothalamo-pituitary-adrenal axis to leptin is impaired in diet-induced obese rats.
Topics: Animals; Corticosterone; Corticotropin-Releasing Hormone; Diet, High-Fat; Hypothalamo-Hypophyseal Sy | 2019 |
Monosodium l-glutamate-obesity onset is associated with disruption of central control of the hypothalamic-pituitary-adrenal axis and autonomic nervous system.
Topics: Animals; Autonomic Nervous System; Corticosterone; Eating; Glucose; Hypothalamo-Hypophyseal System; | 2019 |
Association of high-fat diet with neuroinflammation, anxiety-like defensive behavioral responses, and altered thermoregulatory responses in male rats.
Topics: Amygdala; Animals; Anxiety; Anxiety Disorders; Body Temperature Regulation; Corticosterone; Diet, Hi | 2019 |
Glucocorticoid-Induced Obesity Develops Independently of UCP1.
Topics: Adipose Tissue, Brown; Adiposity; Animals; Cell Respiration; Corticosterone; Down-Regulation; Feedin | 2019 |
Androgens sensitise mice to glucocorticoid-induced insulin resistance and fat accumulation.
Topics: Adipocytes; Adiponectin; Adipose Tissue, Brown; Adiposity; Androgens; Animals; Body Composition; Cor | 2019 |
Prepuberal stress and obesity: effects on serum corticosterone, prolactin, testosterone and precancerous prostate lesions in adult rats.
Topics: Aging; Animals; Corticosterone; Lipopolysaccharides; Male; Obesity; Precancerous Conditions; Prolact | 2019 |
Acute exercise suppresses hypothalamic PTP1B protein level and improves insulin and leptin signaling in obese rats.
Topics: Animals; Blotting, Western; Corticosterone; Hypothalamus; Immunohistochemistry; Inflammation; Insuli | 2013 |
Disrupting hypothalamic glucocorticoid receptors causes HPA axis hyperactivity and excess adiposity.
Topics: Adiposity; Animals; Corticosterone; Female; Hypothalamo-Hypophyseal System; Locomotion; Male; Mice; | 2013 |
Loss of 5α-reductase type 1 accelerates the development of hepatic steatosis but protects against hepatocellular carcinoma in male mice.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Animals; Carcinoma, Hepatocellular; Cell Line; Corticosterone | 2013 |
Obesity and chronic stress are able to desynchronize the temporal pattern of serum levels of leptin and triglycerides.
Topics: Adiponectin; Adipose Tissue, White; Adiposity; Animals; Cholesterol; Chronic Disease; Circadian Rhyt | 2014 |
Early overfeed-induced obesity leads to brown adipose tissue hypoactivity in rats.
Topics: Adipose Tissue, Brown; Animals; Animals, Newborn; Area Under Curve; Blood Glucose; Body Temperature; | 2013 |
Effects of chronic stress and high-fat diet on metabolic and nutritional parameters in Wistar rats.
Topics: Adiposity; Analysis of Variance; Animals; Anti-Inflammatory Agents; Blood Glucose; Body Composition; | 2013 |
Metabolic, behavioral, and reproductive effects of vertical sleeve gastrectomy in an obese rat model of polycystic ovary syndrome.
Topics: Adrenocorticotropic Hormone; Animals; Body Weight; Corticosterone; Disease Models, Animal; Female; G | 2014 |
Pancreatic polypeptide controls energy homeostasis via Npy6r signaling in the suprachiasmatic nucleus in mice.
Topics: Adiposity; Animals; Body Weight; Corticosterone; Diet; Energy Metabolism; Feeding Behavior; Fertilit | 2014 |
Long-term commercial cow's milk consumption and its effects on metabolic parameters associated with obesity in young mice.
Topics: Adipose Tissue, White; Amino Acids, Branched-Chain; Animals; Blood Glucose; Body Weight; Cholesterol | 2014 |
Regulation of expression of relaxin-3 and its receptor RXFP3 in the brain of diet-induced obese rats.
Topics: Animals; Brain; Corticosterone; Diet, High-Fat; Gene Expression Regulation; Glucokinase; Insulin; Ma | 2014 |
Maternal obesity and high-fat diet program offspring metabolic syndrome.
Topics: Animals; Body Composition; Corticosterone; Diet, High-Fat; Eating; Female; Lactation; Lipids; Male; | 2014 |
A novel form of ciliopathy underlies hyperphagia and obesity in Ankrd26 knockout mice.
Topics: Acetylcholine; Animals; Brain; Cilia; Corticosterone; DNA-Binding Proteins; Hyperphagia; Intercellul | 2015 |
Interplay between diet-induced obesity and chronic stress in mice: potential role of FKBP51.
Topics: Animals; Corticosterone; Diet, High-Fat; Disease Models, Animal; Energy Metabolism; Glucose; Hippoca | 2014 |
Maternal high-fat diet alters anxiety behavior and glucocorticoid signaling in adolescent offspring.
Topics: Aging; Animals; Anxiety; Behavior, Animal; Corticosterone; Diet, High-Fat; Female; Glucocorticoids; | 2014 |
Protracted effects of juvenile stressor exposure are mitigated by access to palatable food.
Topics: Adiposity; Animals; Anxiety; Behavior, Animal; Corticosterone; Depression; Diet, High-Fat; Energy In | 2014 |
Changes in morphology and function of adrenal cortex in mice fed a high-fat diet.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Animals; Cells, Cultured; Corticosterone; Diet, High-Fat; D | 2015 |
Weight loss by calorie restriction versus bariatric surgery differentially regulates the hypothalamo-pituitary-adrenocortical axis in male rats.
Topics: Animals; Caloric Restriction; Corticosterone; Corticotropin-Releasing Hormone; Diet, High-Fat; Disea | 2014 |
A peripheral endocannabinoid mechanism contributes to glucocorticoid-mediated metabolic syndrome.
Topics: Animals; Corticosterone; Dyslipidemias; Endocannabinoids; Glucocorticoids; Liver; Metabolic Syndrome | 2015 |
Altered behavior of adult obese rats by monosodium l-glutamate neonatal treatment is related to hypercorticosteronemia and activation of hypothalamic ERK1 and ERK2.
Topics: Animals; Animals, Newborn; Behavior, Animal; Corticosterone; Disease Models, Animal; Enzyme Activati | 2017 |
The direct and indirect effects of corticosterone and primary adipose tissue on MCF7 breast cancer cell cycle progression.
Topics: Adiponectin; Adipose Tissue; Animals; Breast Neoplasms; Cell Cycle; Cell Proliferation; Corticostero | 2015 |
Aging, glucocorticoids and developmental programming.
Topics: Aging; Animals; Corticosterone; Female; Male; Obesity; Rats; Rats, Wistar; Sex Characteristics | 2015 |
Ondansetron attenuates co-morbid depression and anxiety associated with obesity by inhibiting the biochemical alterations and improving serotonergic neurotransmission.
Topics: Animals; Anxiety; Behavior, Animal; Body Weight; Brain; Citalopram; Corticosterone; Depression; Diet | 2015 |
Bovine serum albumin as the dominant form of dietary protein reduces subcutaneous fat mass, plasma leptin and plasma corticosterone in high fat-fed C57/BL6J mice.
Topics: Adiposity; Animals; Carnitine O-Palmitoyltransferase; Corticosterone; Diet, High-Fat; Dietary Fats; | 2015 |
High Dietary Fat Intake during Lactation Promotes the Development of Social Stress-Induced Obesity in the Offspring of Mice.
Topics: Animal Feed; Animals; Corticosterone; Diet; Dietary Fats; Female; Lactation; Male; Maternal Nutritio | 2015 |
Hypercaloric diet modulates effects of chronic stress: a behavioral and biometric study on rats.
Topics: Adiposity; Animals; Anxiety; Behavior, Animal; Body Weight; Corticosterone; Diet; Energy Intake; Fee | 2015 |
A High-Fat Diet Causes Impairment in Hippocampal Memory and Sex-Dependent Alterations in Peripheral Metabolism.
Topics: Animals; Blood Glucose; Corticosterone; Diet, High-Fat; Female; Hippocampus; Male; Obesity; Rats; Re | 2016 |
Depot- and sex-specific effects of maternal obesity in offspring's adipose tissue.
Topics: Adipose Tissue; Animals; Body Weight; Corticosterone; Female; Glucose Intolerance; Hyperinsulinism; | 2016 |
Maternal testosterone and reproductive outcome in a rat model of obesity.
Topics: Animals; Corticosterone; Female; Hair; Male; Obesity; Pregnancy; Pregnancy Outcome; Rats; Rats, Inbr | 2016 |
The 11β-hydroxysteroid dehydrogenase type 1 inhibitor protects against the insulin resistance and hepatic steatosis in db/db mice.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Benzylidene Compounds; Blood Glucose; Body Wei | 2016 |
Fructose and stress induce opposite effects on lipid metabolism in the visceral adipose tissue of adult female rats through glucocorticoid action.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Acetyl-CoA Carboxylase; Animals; Corticosterone; Diet; | 2017 |
Relationship between the Balance of Hypertrophic/Hyperplastic Adipose Tissue Expansion and the Metabolic Profile in a High Glucocorticoids Model.
Topics: Adipocytes; Adipogenesis; Adiposity; Animals; Cell Differentiation; Cell Proliferation; Cells, Cultu | 2016 |
Obesity Disrupts the Rhythmic Profiles of Maternal and Fetal Progesterone in Rat Pregnancy.
Topics: Animals; Circadian Rhythm; Corticosterone; Female; Obesity; Pregnancy; Pregnancy, Animal; Progestero | 2016 |
ABCC1 confers tissue-specific sensitivity to cortisol versus corticosterone: A rationale for safer glucocorticoid replacement therapy.
Topics: Addison Disease; Adipose Tissue; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Anima | 2016 |
Elevated Steroid Hormone Production in the db/db Mouse Model of Obesity and Type 2 Diabetes.
Topics: Adrenal Cortex Hormones; Aldosterone; Animals; Corticosterone; Desoxycorticosterone; Diabetes Mellit | 2017 |
Reduction of hepatic glucocorticoid receptor and hexose-6-phosphate dehydrogenase expression ameliorates diet-induced obesity and insulin resistance in mice.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Blood Glucose; Body Weight; Carbenoxolone; Car | 2008 |
Leptin acts in the periphery to protect thymocytes from glucocorticoid-mediated apoptosis in the absence of weight loss.
Topics: Adrenalectomy; Age Factors; Animals; Apoptosis; Atrophy; Chimera; Corticosterone; Flow Cytometry; Le | 2008 |
Early undernutrition leads to long-lasting reductions in body weight and adiposity whereas increased intake increases cardiac fibrosis in male rats.
Topics: Adiposity; Aging; Animals; Animals, Newborn; Blood Pressure; Body Weight; Corticosterone; Energy Int | 2008 |
Prolonged but not short negative energy condition restored corticoadrenal leptin sensitivity in the hypothalamic obese rat.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Animals, Newborn; Blood Proteins; Body Weight; | 2009 |
Effects of BDNF, T3, and corticosterone on expression of the hypothalamic obesity gene network in vivo and in vitro.
Topics: Age Factors; Animals; Body Composition; Brain-Derived Neurotrophic Factor; Cells, Cultured; Chick Em | 2009 |
Metabolic consequences and vulnerability to diet-induced obesity in male mice under chronic social stress.
Topics: Adipose Tissue; Aggression; Animals; Body Weight; Corticosterone; Diet; Dietary Fats; Disease Models | 2009 |
Diet-induced obesity alters behavior as well as serum levels of corticosterone in F344 rats.
Topics: Aggression; Analysis of Variance; Animals; Anxiety; Body Weight; Corticosterone; Diet; Disease Model | 2009 |
Pregnancy and lactation have anti-obesity and anti-diabetic effects in A(y)/a mice.
Topics: Age Factors; Animals; Blood Glucose; Body Weight; Breast Feeding; Corticosterone; Diabetes Mellitus; | 2010 |
[The effect of the "yellow" mutation at the mouse agouti locus on the hormonal profile of pregnancy and lactation].
Topics: Agouti Signaling Protein; Animals; Blood Glucose; Corticosterone; Female; Insulin; Lactation; Leptin | 2009 |
Evolution and obesity: resistance of obese-prone rats to a challenge of food restriction and wheel running.
Topics: Adaptation, Physiological; Animals; Corticosterone; Eating; Energy Metabolism; Food Deprivation; Gen | 2010 |
Food intake during the normal activity phase prevents obesity and circadian desynchrony in a rat model of night work.
Topics: Animals; Behavior, Animal; Body Temperature; Body Weight; Circadian Rhythm; Corticosterone; Disease | 2010 |
Post-weaning voluntary exercise exerts long-term moderation of adiposity in males but not in females in an animal model of early-onset obesity.
Topics: Adiponectin; Adipose Tissue; Adiposity; Animals; Body Weight; Corticosterone; Creatinine; Eating; Es | 2010 |
Association of neuropeptide W, but not obestatin, with energy intake and endocrine status in Zucker rats. A new player in long-term stress-feeding interactions.
Topics: Animals; Corticosterone; Down-Regulation; Eating; Energy Intake; Fasting; Ghrelin; Homeostasis; Insu | 2010 |
Obesity/hyperleptinemic phenotype adversely affects hippocampal plasticity: effects of dietary restriction.
Topics: Adiposity; Animals; Area Under Curve; Autoradiography; Body Weight; Corticosterone; Disease Models, | 2011 |
White adipose tissue re-growth after partial lipectomy in high fat diet induced obese wistar rats.
Topics: Abdominal Cavity; Adipocytes; Adipose Tissue, Brown; Adipose Tissue, White; Animals; Body Weight; Co | 2011 |
Traits of the metabolic syndrome alter corpulent obesity in LAN, SHR and DSS rats: behavioral and metabolic interactions with adrenalectomy.
Topics: Adipose Tissue; Adrenalectomy; Analysis of Variance; Animals; Behavior, Animal; Body Composition; Bo | 2011 |
Differential effects of glucocorticoids on energy homeostasis in Syrian hamsters.
Topics: Adipose Tissue; Animals; Body Weight; Cholesterol; Corticosterone; Cricetinae; Cushing Syndrome; Eat | 2011 |
The interleukin-6 and noradrenaline mediated inflammation-stress feedback mechanism is dysregulated in metabolic syndrome: effect of exercise.
Topics: Adaptation, Physiological; Analysis of Variance; Animals; Blood Glucose; C-Reactive Protein; Chromat | 2011 |
High-fat diet selectively protects against the effects of chronic social stress in the mouse.
Topics: Animals; Anxiety; Corticosterone; Depression; Diet, High-Fat; Female; Insulin; Leptin; Male; Mice; M | 2011 |
Circadian integration of sleep-wake and feeding requires NPY receptor-expressing neurons in the mediobasal hypothalamus.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Caloric Restriction; Circadian Rhythm; Corticosterone; Eat | 2011 |
Double blockade of angiotensin II (AT(1) )-receptors and ACE does not improve weight gain and glucose homeostasis better than single-drug treatments in obese rats.
Topics: Adipose Tissue; Adrenocorticotropic Hormone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers | 2012 |
Neurological and stress related effects of shifting obese rats from a palatable diet to chow and lean rats from chow to a palatable diet.
Topics: Adipose Tissue; Animals; Blood Glucose; Body Weight; Corticosterone; Corticotropin-Releasing Hormone | 2012 |
Diet and exercise in an obese mouse fed a high-fat diet improve metabolic health and reverse perturbed sperm function.
Topics: Acrosome Reaction; Animals; Blood Glucose; Body Composition; Cholesterol; Corticosterone; Diet, High | 2012 |
Hypothalamic Fkbp51 is induced by fasting, and elevated hypothalamic expression promotes obese phenotypes.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Corticosterone; Energy Intake; Fasting; Gene Expression Pr | 2012 |
Diet-induced obesity promotes depressive-like behaviour that is associated with neural adaptations in brain reward circuitry.
Topics: Animals; Anxiety; Behavior, Animal; Corticosterone; Depression; Diet, High-Fat; Disease Models, Anim | 2013 |
Prenatal stress increases the obesogenic effects of a high-fat-sucrose diet in adult rats in a sex-specific manner.
Topics: Adiposity; Animals; Corticosterone; Diet, High-Fat; Dietary Carbohydrates; Female; Insulin; Intra-Ab | 2013 |
Characteristics of glucocorticoid synthesis-related factors in the adrenals of obese Zucker rats (short communication).
Topics: Adrenal Glands; Animals; Cholesterol Side-Chain Cleavage Enzyme; Corticosterone; Cytochrome P-450 CY | 2012 |
Benzofuran derivatives inhibit 11β-hydroxysteroid dehydrogenase type 1 activity in rat adipose tissue.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 3T3-L1 Cells; Animals; Benzofurans; Corticosterone; Dos | 2012 |
Peripubertal-onset but not adult-onset obesity increases IGF-I and drives development of lean mass, which may lessen the metabolic impairment in adult obesity.
Topics: Adrenocorticotropic Hormone; Aging; Animals; Body Composition; Corticosterone; Diet, High-Fat; Disea | 2012 |
Cafeteria diet-induced obesity plus chronic stress alter serum leptin levels.
Topics: Adipose Tissue; Animals; Body Weight; Corticosterone; Diet; Disease Models, Animal; Energy Intake; L | 2012 |
Angiotensin II impairs glucose utilization in obese Zucker rats by increasing HPA activity via an adrenal-dependent mechanism.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Angiotensin II; Animals; Blood Glucose; Corticosterone; | 2013 |
Anatomic, hematologic, and biochemical features of C57BL/6NCrl mice maintained on chronic oral corticosterone.
Topics: Adrenal Glands; Analysis of Variance; Animals; Case-Control Studies; Corticosterone; Dose-Response R | 2012 |
The lipocalin-type prostaglandin D2 synthase knockout mouse model of insulin resistance and obesity demonstrates early hypothalamic-pituitary-adrenal axis hyperactivity.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Genotype; Hypercholesterolemia; Hyperglycemia; | 2013 |
Chronic circadian clock disruption induces expression of the cardiovascular risk factor plasminogen activator inhibitor-1 in mice.
Topics: Animals; Cardiovascular Diseases; Chronic Disease; Chronobiology Disorders; Corticosterone; Diet, Hi | 2013 |
Carbenoxolone treatment ameliorated metabolic syndrome in WNIN/Ob obese rats, but induced severe fat loss and glucose intolerance in lean rats.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipocytes; Adipose Tissue; Adrenal Glands; Animals; Bo | 2012 |
Differential effects of chronic social stress and fluoxetine on meal patterns in mice.
Topics: Animals; Antidepressive Agents, Second-Generation; Chronic Disease; Corticosterone; Eating; Energy I | 2013 |
Maternal obesity during the preconception and early life periods alters pancreatic development in early and adult life in male mouse offspring.
Topics: Adiposity; Animals; Blood Glucose; Blood Pressure; Body Weight; Corticosterone; Diet, High-Fat; Dise | 2013 |
Adrenalectomy abolishes the food-induced hypothalamic serotonin release in both normal and monosodium glutamate-obese rats.
Topics: Adrenalectomy; Animals; Corticosterone; Eating; Hypothalamus; Male; Obesity; Rats; Rats, Wistar; Ser | 2002 |
Energy restriction reduces fractional calcium absorption in mature obese and lean rats.
Topics: Animals; Body Weight; Bone and Bones; Calcium; Calcium, Dietary; Corticosterone; Creatinine; Diet, R | 2002 |
Effects of a high-fat diet and strain on hypothalamic gene expression in rats.
Topics: Animals; Corticosterone; Corticotropin-Releasing Hormone; Dietary Fats; Eating; Gene Expression; Hyp | 2002 |
Leptin activation of corticosterone production in hepatocytes may contribute to the reversal of obesity and hyperglycemia in leptin-deficient ob/ob mice.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Blood Glucose; Body Weight; Corticosterone; Di | 2003 |
Stress facilitates body weight gain in genetically predisposed rats on medium-fat diet.
Topics: Animal Feed; Animals; Corticosterone; Corticotropin-Releasing Hormone; Dietary Fats; Eating; Energy | 2003 |
Melanin-concentrating hormone is a critical mediator of the leptin-deficient phenotype.
Topics: Adipose Tissue, Brown; Animals; Base Sequence; Body Composition; Body Temperature Regulation; Body W | 2003 |
Lutein interacts with ascorbic acid more frequently than with alpha-tocopherol to alter biomarkers of oxidative stress in female zucker obese rats.
Topics: alpha-Tocopherol; Animals; Ascorbic Acid; Biomarkers; Corticosterone; Dose-Response Relationship, Dr | 2003 |
Study of the alteration of gene expression in adipose tissue of diet-induced obese mice by microarray and reverse transcription-polymerase chain reaction analyses.
Topics: Adipose Tissue; Animals; Blood Glucose; Body Weight; Corticosterone; Dietary Fats; Gene Expression; | 2003 |
Chronic neuropeptide Y infusion into the lateral ventricle induces sustained feeding and obesity in mice lacking either Npy1r or Npy5r expression.
Topics: Adipose Tissue; Animals; Body Weight; Corticosterone; Drinking; Eating; Feeding Behavior; Hyperphagi | 2004 |
Absence of hormone-sensitive lipase inhibits obesity and adipogenesis in Lep ob/ob mice.
Topics: Adipocytes; Agouti-Related Protein; Animals; Blotting, Northern; Blotting, Western; Corticosterone; | 2004 |
Interaction between corticosterone and insulin in obesity: regulation of lard intake and fat stores.
Topics: Adipose Tissue; Adrenalectomy; Animals; Corticosterone; Dietary Fats; Drug Interactions; Energy Inta | 2004 |
Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation.
Topics: Acute-Phase Proteins; Adipose Tissue, Brown; Animals; Body Temperature Regulation; Corticosterone; D | 2004 |
Different responsiveness in body weight and hepatic 11beta-hydroxysteroid dehydrogenase (11beta-HSD) type 1 mrna to 11beta-HSD inhibition by glycyrrhetinic acid treatment in obese and lean zucker rats.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Animals; Body Weight; Corticosterone; Eating; Gene Expression | 2004 |
Expression levels of genes likely involved in glucose-sensing in the obese Zucker rat brain.
Topics: Animals; Blood Glucose; Corticosterone; Energy Metabolism; Female; Gene Expression Regulation; Gluca | 2004 |
Effects of diet and time of the day on serum and CSF leptin levels in Osborne-Mendel and S5B/Pl rats.
Topics: Animals; Body Weight; Circadian Rhythm; Corticosterone; Diet; Dietary Fats; DNA-Binding Proteins; Do | 2004 |
Agouti yellow mutation increases adrenal response to ACTH in mice.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Agouti Signaling Protein; Agouti-Related Protein; Anima | 2004 |
Physiological regulation of hypothalamic IL-1beta gene expression by leptin and glucocorticoids: implications for energy homeostasis.
Topics: Adrenalectomy; Animal Feed; Animals; Body Weight; Corticosterone; Eating; Energy Metabolism; Fasting | 2004 |
Corticosterone-dependent metabolic and neuroendocrine abnormalities in obese Zucker rats in relation to feeding.
Topics: Animals; Blood Glucose; Body Composition; Body Weight; Corticosterone; Corticotropin-Releasing Hormo | 2005 |
A new function of the leptin receptor: mediation of the recovery from lipopolysaccharide-induced hypothermia.
Topics: Animals; Corticosterone; Cytokines; Encephalitis; Fever; Hypothermia; Kinetics; Lipopolysaccharides; | 2004 |
Impact of transient correction of increased adrenocortical activity in hypothalamo-damaged, hyperadipose female rats.
Topics: Adipocytes; Adipose Tissue; Adiposity; Adrenal Cortex; Animals; Blood Glucose; Cells, Cultured; Cort | 2006 |
A polygenic model of the metabolic syndrome with reduced circulating and intra-adipose glucocorticoid action.
Topics: Adipose Tissue; Animals; Blood Glucose; Corticosterone; Crosses, Genetic; Cushing Syndrome; Epididym | 2005 |
BSB: a new mouse model of multigenic obesity.
Topics: Animals; Body Weight; Corticosterone; Cortisone; Crosses, Genetic; Disease Models, Animal; Female; G | 1993 |
Adrenalectomy and castration in the genetically obese (ob/ob) mouse.
Topics: Adrenal Glands; Adrenalectomy; Animals; Body Weight; Castration; Corticosterone; Female; Follicle St | 1993 |
Muraglitazar, a novel dual (alpha/gamma) peroxisome proliferator-activated receptor activator, improves diabetes and other metabolic abnormalities and preserves beta-cell function in db/db mice.
Topics: Adiponectin; Animals; Blood Glucose; Corticosterone; Diabetes Mellitus, Type 2; Diet; Female; Glycin | 2006 |
Adiponectin is regulated differently by chronic exercise than by weight-matched food restriction in hyperphagic and obese OLETF rats.
Topics: Adipocytes; Adiponectin; Adipose Tissue; Animals; Corticosterone; Disease Models, Animal; Epididymis | 2006 |
Distinct endocrine effects of chronic haloperidol or risperidone administration in male rats.
Topics: Adipose Tissue; Animals; Antipsychotic Agents; Appetite; Body Weight; Corticosterone; Diabetes Melli | 2006 |
Neuropeptide Y deficiency attenuates responses to fasting and high-fat diet in obesity-prone mice.
Topics: Aging; Animals; Appetite; Blood Glucose; Body Weight; Corticosterone; Dietary Fats; Eating; Fasting; | 2006 |
Human adenovirus 36 induces adiposity, increases insulin sensitivity, and alters hypothalamic monoamines in rats.
Topics: Adenovirus Infections, Human; Adenoviruses, Human; Adipose Tissue; Animals; CCAAT-Enhancer-Binding P | 2006 |
Insulin resistance and low sympathetic nerve activity in the Tsumura Suzuki obese diabetic mouse: a new model of spontaneous type 2 diabetes mellitus and obesity.
Topics: Adiponectin; Adipose Tissue, Brown; Adrenal Glands; Animals; Corticosterone; Diabetes Mellitus, Type | 2006 |
A possible role for melanocortin peptides in longitudinal growth.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Animals; Corticosterone; Eating; gamma-MSH; Growth; Lept | 2006 |
Hippocampal 11beta-hydroxysteroid dehydrogenase type 1 messenger ribonucleic acid expression has a diurnal variability that is lost in the obese Zucker rat.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Cerebral Cortex; Circadian Rhythm; Corticoster | 2007 |
Effects of the CRF1 receptor antagonist SSR125543 on energy balance and food deprivation-induced neuronal activation in obese Zucker rats.
Topics: Animals; Blood Glucose; Corticosterone; Corticotropin-Releasing Hormone; Energy Metabolism; Fatty Ac | 2007 |
Chemical gastric inhibitory polypeptide receptor antagonism protects against obesity, insulin resistance, glucose intolerance and associated disturbances in mice fed high-fat and cafeteria diets.
Topics: Adiponectin; Animals; Blood Glucose; Body Weight; Corticosterone; Dietary Fats; Eating; Gastric Inhi | 2007 |
GIP receptor antagonism reverses obesity, insulin resistance, and associated metabolic disturbances induced in mice by prolonged consumption of high-fat diet.
Topics: Adipokines; Adipose Tissue; Animals; Anti-Obesity Agents; Blood Glucose; Body Weight; Corticosterone | 2007 |
Carbenoxolone treatment attenuates symptoms of metabolic syndrome and atherogenesis in obese, hyperlipidemic mice.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipose Tissue; Agouti Signaling Protein; Animals; Athe | 2007 |
Comparison of the metabolic effects of GIP receptor antagonism and PYY(3-36) receptor activation in high fat fed mice.
Topics: Animals; Blood Glucose; Corticosterone; Dietary Fats; Gastric Inhibitory Polypeptide; Glucagon; Gluc | 2007 |
Synergy between leptin therapy and a seemingly negligible amount of voluntary wheel running prevents progression of dietary obesity in leptin-resistant rats.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipose Tissue; Animals; Corticosterone; Diet; Eating; | 2008 |
[Repeating of emotional stress prevents development of melanocortin obesity and type 2 diabetes in the mice with the Agouti yellow mutation].
Topics: Agouti Signaling Protein; Animals; Brain; Carbohydrate Metabolism; Corticosterone; Diabetes Mellitus | 2007 |
Sub-chronic administration of the 11beta-HSD1 inhibitor, carbenoxolone, improves glucose tolerance and insulin sensitivity in mice with diet-induced obesity.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Blood Glucose; Body Weight; Carbenoxolone; Cor | 2008 |
RU486 did not exacerbate cytokine release in mice challenged with LPS nor in db/db mice.
Topics: Adrenocorticotropic Hormone; Animals; Blood Glucose; Chemokine CCL2; Corticosterone; Diabetes Mellit | 2008 |
Effect of corticotropin on brown adipose tissue mitochondrial GDP binding in obese rats.
Topics: Adipose Tissue, Brown; Adrenalectomy; Adrenocorticotropic Hormone; Animals; Corticosterone; Guanine | 1984 |
Regulation of hepatic tyrosine aminotransferase in genetically obese rats.
Topics: Adrenalectomy; Aging; Amino Acids; Animals; Corticosterone; Diet; Disease Models, Animal; Enzyme Act | 1983 |
Hypothalamic hyperinsulinemia and obesity: role of adrenal glucocorticoids.
Topics: Adrenalectomy; Animals; Blood Glucose; Body Weight; Corticosterone; Female; Hyperinsulinism; Insulin | 1983 |
Anorexia after adrenalectomy in gold thioglucose-treated obese mice.
Topics: Adrenalectomy; Animals; Anorexia; Aurothioglucose; Blood Glucose; Corticosterone; Feeding and Eating | 1983 |
Glycemic response to selected sympathomimetics in stressed normal and goldthioglucose mice.
Topics: Animals; Aurothioglucose; Blood Glucose; Corticosterone; Diabetes Mellitus; Diabetes Mellitus, Exper | 1983 |
Diurnal rhythm for corticosterone in obese (ob/ob) diabetes (db/db) and gold-thioglucose-induced obesity in mice.
Topics: Aging; Animals; Aurothioglucose; Body Weight; Circadian Rhythm; Corticosterone; Diabetes Mellitus; D | 1983 |
Specific depletion of body fat in parabiotic partners of tube-fed obese rats.
Topics: 3-Hydroxybutyric Acid; Adipose Tissue; Animals; Blood Glucose; Body Weight; Corticosterone; Energy I | 1984 |
The effects of corticosterone, cold exposure and overfeeding with sucrose on brown adipose tissue of obese Zucker rats (fa/fa).
Topics: Adipose Tissue, Brown; Adrenalectomy; Animals; Cold Temperature; Corticosterone; Guanosine Diphospha | 1983 |
Starvation and age effects on glycoregulation and hormone levels of C57BL/6Job/ob mice.
Topics: Age Factors; Animals; Blood Glucose; Corticosterone; Female; Glucagon; Glycolysis; Hormones; Insulin | 1982 |
Non-essential role of dietary factors in the development of diabetes in ob/ob mice.
Topics: Animals; Biometry; Blood Glucose; Body Weight; Corticosterone; Diabetes Mellitus; Diet; Glucagon; In | 1981 |
[Hypothalamic obesity in old rats].
Topics: Age Factors; Animals; Blood Glucose; Brain Diseases; Cholesterol; Corticosterone; Drinking Behavior; | 1980 |
Effects of adrenalectomy and corticosterone administration on hypothalamic obesity in rats.
Topics: Adrenal Glands; Analysis of Variance; Animals; Corticosterone; Female; Humans; Hyperphagia; Hypothal | 1982 |
Chronic cerebroventricular galanin does not induce sustained hyperphagia or obesity.
Topics: Animals; Blood Glucose; Body Weight; Corticosterone; Dietary Carbohydrates; Dietary Fats; Eating; Ga | 1994 |
The effect of DHEA given chronically to Zucker rats.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Blood Glucose; Corticosterone; Dehydroepiandro | 1995 |
Growth and maturation of primary-cultured adipocytes from lean and ob/ob mice.
Topics: 1-Methyl-3-isobutylxanthine; Adipocytes; Animals; Cattle; Cell Cycle; Cell Differentiation; Cell Div | 1995 |
Pressor effects of portal venous oleate infusion. A proposed mechanism for obesity hypertension.
Topics: Analysis of Variance; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Caprylates; C | 1995 |
Decreased central and peripheral catecholaminergic activation in obese Zucker rats.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Epinephrine; Immobilization; Male; Norepinephr | 1995 |
Gender differences in adrenal cortex steroid production in SHR/N-corpulent rats.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Aldosterone; Animals; Corticosterone; Estrogens; Female; Go | 1994 |
Long-term administration of dexfenfluramine to genetically obese (ob/ob) and lean mice: body weight and brain serotonin changes.
Topics: Animals; Blood Glucose; Body Weight; Brain Chemistry; Corticosterone; Dietary Fats; Female; Fenflura | 1994 |
Effect of adrenalectomy on glucose tolerance and lipid metabolism in gold-thioglucose obese mice.
Topics: Adrenalectomy; Animals; Aurothioglucose; Blood Glucose; Body Weight; Corticosterone; Eating; Ether; | 1994 |
Dexamethasone-induced hyperglycemia in obese Avy/a (viable yellow) female mice entails preferential induction of a hepatic estrogen sulfotransferase.
Topics: Animals; Blood Glucose; Corticosterone; Dexamethasone; Estradiol; Female; Hyperglycemia; Insulin; Li | 1994 |
Overfeeding-induced obesity in rats: insulin sensitivity and autonomic regulation of metabolism.
Topics: Animals; Blood Glucose; Body Composition; Corticosterone; Diet; Epinephrine; Fatty Acids, Nonesterif | 1993 |
Pro-opiomelanocortin messenger RNA levels in anterior pituitaries of female Wistar fatty rats.
Topics: Adrenocorticotropic Hormone; Animals; Blotting, Northern; Corticosterone; Female; Nucleic Acid Hybri | 1993 |
Hypothalamic neuropeptide Y messenger ribonucleic acid levels in pre-obese and genetically obese (fa/fa) rats; potential regulation thereof by corticotropin-releasing factor.
Topics: Adipose Tissue; Aging; Animals; Base Sequence; Brain; Corticosterone; Corticotropin-Releasing Hormon | 1993 |
Effect of adrenalectomy on the development of a pancreatic islet lesion in fa/fa rats.
Topics: Adrenalectomy; Animals; Blood Glucose; Body Weight; Cells, Cultured; Corticosterone; Female; Glucoki | 1996 |
Metabolic and endocrine effects of interleukin-1 in obese, diabetic Zucker fa/fa rats.
Topics: Animals; Blood Glucose; Cholesterol; Corticosterone; Diabetes Mellitus; Diabetes Mellitus, Type 2; D | 1996 |
Expression of corticotropin-releasing factor and its receptors in the brain of lean and obese Zucker rats.
Topics: Adrenocorticotropic Hormone; Animals; Biological Assay; Brain; Corticosterone; Corticotropin-Releasi | 1996 |
Adrenalectomy prevents the obesity syndrome produced by chronic central neuropeptide Y infusion in normal rats.
Topics: Adipose Tissue; Adrenalectomy; Animals; Corticosterone; Drug Administration Schedule; Female; Gene E | 1997 |
Hormonal and metabolic adaptations to fasting in monosodium glutamate-obese rats.
Topics: Adaptation, Physiological; Adipose Tissue; Animals; Animals, Newborn; Corticosterone; Fasting; Fatty | 1997 |
Effects of the glucocorticoid II receptor antagonist mifepristone on hypertension in the obese Zucker rat.
Topics: Aldosterone; Animals; Blood Pressure; Corticosterone; Hypertension; Male; Mifepristone; Obesity; Rat | 1997 |
Overexpression of Agrt leads to obesity in transgenic mice.
Topics: Actins; Adipose Tissue; Agouti-Related Protein; Animals; Body Weight; Corticosterone; Disease Models | 1997 |
Inhibition of food response to intracerebroventricular injection of leptin is attenuated in rats with diet-induced obesity.
Topics: Adipose Tissue; Animals; Blood Glucose; Body Weight; Cerebral Ventricles; Corticosterone; Diet; Ener | 1997 |
Central leptin stimulates corticosterone secretion at the onset of the dark phase.
Topics: Analysis of Variance; Animals; Blood Glucose; Cerebral Ventricles; Circadian Rhythm; Corticosterone; | 1997 |
Independent and additive effects of central POMC and leptin pathways on murine obesity.
Topics: Adrenalectomy; Agouti Signaling Protein; Alleles; Animals; Arcuate Nucleus of Hypothalamus; Blood Gl | 1997 |
Effects of intracerebroventricular infusion of leptin in obese Zucker rats.
Topics: Adipose Tissue, Brown; Animals; Blood Glucose; Body Temperature; Body Weight; Brain; Corticosterone; | 1997 |
Functional activation of CRH neurons and expression of the genes encoding CRH and its receptors in food-deprived lean (Fa/?) and obese (fa/fa) Zucker rats.
Topics: Animals; Blood Glucose; Body Weight; Brain; Corticosterone; Corticotropin-Releasing Hormone; Food De | 1997 |
Chronic leptin infusion increases arterial pressure.
Topics: Aldosterone; Animals; Aorta, Abdominal; Blood Glucose; Blood Pressure; Brain; Carotid Arteries; Cort | 1998 |
Obesity on a high-fat diet: role of hypothalamic galanin in neurons of the anterior paraventricular nucleus projecting to the median eminence.
Topics: Adipose Tissue; Animals; Behavior, Animal; Blood Glucose; Corticosterone; Dietary Carbohydrates; Die | 1998 |
Severe leptin resistance in brown fat-deficient uncoupling protein promoter-driven diphtheria toxin A mice despite suppression of hypothalamic neuropeptide Y and circulating corticosterone concentrations.
Topics: Adipose Tissue, Brown; Animals; Blood Glucose; Carrier Proteins; Corticosterone; Diphtheria Toxin; D | 1998 |
Effects of leptin on corticotropin-releasing factor (CRF) synthesis and CRF neuron activation in the paraventricular hypothalamic nucleus of obese (ob/ob) mice.
Topics: Adipose Tissue; Animals; Arcuate Nucleus of Hypothalamus; Body Weight; Corticosterone; Corticotropin | 1998 |
Orchiectomy and response to testosterone in the development of obesity in young Otsuka-Long-Evans-Tokushima Fatty (OLETF) rats.
Topics: Animals; Base Sequence; Blood Glucose; Cohort Studies; Corticosterone; Diabetes Mellitus, Type 2; Di | 1998 |
Behavioral and endocrine traits of obesity-prone and obesity-resistant rats on macronutrient diets.
Topics: Adipose Tissue; Animals; Behavior, Animal; Blood Glucose; Body Weight; Corticosterone; Dietary Carbo | 1998 |
Effect of oleoyl-estrone administration on corticosterone binding to tissues of lean and obese Zucker rats.
Topics: Adipose Tissue; Animals; Anti-Obesity Agents; Blotting, Northern; Body Weight; Corticosterone; Estro | 1998 |
Leptin and corticosterone have opposite effects on food intake and the expression of UCP1 mRNA in brown adipose tissue of lep(ob)/lep(ob) mice.
Topics: Adipose Tissue, Brown; Adrenalectomy; Animals; Carrier Proteins; Corticosterone; Drug Interactions; | 1998 |
Zucker obese rats are insensitive to the CRH-increasing effect of oleoyl-estrone.
Topics: Adrenocorticotropic Hormone; Animals; Anti-Obesity Agents; Appetite; Corticosterone; Corticotropin-R | 1998 |
Neuropeptide Y in relation to carbohydrate intake, corticosterone and dietary obesity.
Topics: Adipose Tissue; Animals; Corticosterone; Diet; Dietary Carbohydrates; Dietary Fats; Hypothalamus; Ma | 1998 |
Mahogany (mg) stimulates feeding and increases basal metabolic rate independent of its suppression of agouti.
Topics: Agouti Signaling Protein; Animals; Basal Metabolism; Blood Glucose; Corticosterone; Hyperphagia; Ins | 1998 |
Effects of leptin adipose tissue lipoprotein lipase in the obese ob/ob mouse.
Topics: Adipose Tissue; Animals; Corticosterone; Injections, Subcutaneous; Insulin; Leptin; Lipoprotein Lipa | 1998 |
Leptin deficiency enhances sensitivity to endotoxin-induced lethality.
Topics: Animals; Blood Glucose; Carrier Proteins; Cells, Cultured; Corticosterone; Cytokines; Drug Resistanc | 1999 |
Corticosterone binding to tissues of adrenalectomized lean and obese Zucker rats.
Topics: Adipose Tissue; Adipose Tissue, Brown; Adrenalectomy; Aldosterone; Animals; Brain; Corticosterone; D | 1998 |
Induction of obesity and hyperleptinemia by central glucocorticoid infusion in the rat.
Topics: Animals; Body Weight; Brain; Carrier Proteins; Corticosterone; Corticotropin-Releasing Hormone; Dexa | 1999 |
Physiologic and endocrinologic characterization of male sex-biased diabetes in C57BLKS/J mice congenic for the fat mutation at the carboxypeptidease E locus.
Topics: Animals; Blood Glucose; Body Weight; Carboxypeptidase H; Carboxypeptidases; Corticosterone; Crosses, | 1999 |
Modulation of triglyceride metabolism by glucocorticoids in diet-induced obesity.
Topics: Adipose Tissue; Adrenalectomy; Animals; Body Weight; Corticosterone; Diet; Dietary Fats; Dietary Suc | 1999 |
Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; alpha-MSH; Animals; Catecholamines; Cortic | 1999 |
Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety.
Topics: Adrenal Glands; Age Factors; Animals; Anxiety; Brain; Corticosterone; Cushing Syndrome; Disease Mode | 1999 |
Short-term treatment with estrone oleate in liposomes (Merlin-2) does not affect the expression of the ob gene in Zucker obese rats.
Topics: Animals; Blood Glucose; Carrier Proteins; Corticosterone; Estrone; Female; Gene Expression Regulatio | 1999 |
Corticotropin-releasing hormone-binding protein in brain and pituitary of food-deprived obese (fa/fa) Zucker rats.
Topics: Amygdala; Animals; Blood Glucose; Body Weight; Brain; Carrier Proteins; Corticosterone; Eating; Fast | 1999 |
Contribution of hyperinsulinemia to modulation of lipoprotein lipase activity in the obese Zucker rat.
Topics: Adipose Tissue; Animals; Blood Glucose; Corticosterone; Fatty Acids, Nonesterified; Hyperinsulinism; | 2000 |
Understanding the role of glucocorticoids in obesity: tissue-specific alterations of corticosterone metabolism in obese Zucker rats.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adrenal Cortex H | 2000 |
Regulation of hypothalamic proopiomelanocortin by leptin in lean and obese rats.
Topics: Animals; Corticosterone; Cytoplasm; Gene Expression; Hypothalamus; Injections, Intraventricular; Lep | 1999 |
A novel neurotensin peptide analog given extracranially decreases food intake and weight in rodents.
Topics: Animals; Blood Glucose; Body Weight; Corticosterone; Dopamine; Dose-Response Relationship, Drug; Dru | 2000 |
Central exendin-4 infusion reduces body weight without altering plasma leptin in (fa/fa) Zucker rats.
Topics: Adipose Tissue; Adipose Tissue, Brown; Animals; Body Temperature; Body Weight; Brain; Corticosterone | 2000 |
Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass.
Topics: Adipose Tissue; Age Factors; alpha-MSH; Animals; Blotting, Southern; Body Temperature; Body Weight; | 2000 |
Effect of chronic central infusion of murine and human leptin in lean Zucker rats.
Topics: Adipose Tissue; Adipose Tissue, Brown; Animals; Body Temperature Regulation; Body Weight; Brain; Car | 2000 |
Differential expression of hypothalamic neuropeptides in the early phase of diet-induced obesity in mice.
Topics: Agouti-Related Protein; Animals; Area Under Curve; Body Composition; Body Weight; Corticosterone; Di | 2000 |
Adrenalectomy reverses obese phenotype and restores hypothalamic melanocortin tone in leptin-deficient ob/ob mice.
Topics: Adrenalectomy; Agouti-Related Protein; Animals; Blood Glucose; Blotting, Northern; Body Weight; Cort | 2000 |
Excess portal venous long-chain fatty acids induce syndrome X via HPA axis and sympathetic activation.
Topics: Animals; Blood Pressure; Caprylates; Corticosterone; Epinephrine; Glucose Tolerance Test; Heart Rate | 2000 |
The effect of dehydroepiandrosterone on Zucker rats selected for fat food preference.
Topics: Animals; Body Weight; Corticosterone; Dehydroepiandrosterone; Dietary Carbohydrates; Dietary Fats; D | 2000 |
Mechanisms of dysregulation of 11 beta-hydroxysteroid dehydrogenase type 1 in obese Zucker rats.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adipose Tissue; Adrenal Glands; Adrenalectomy; Analysis of Va | 2000 |
Ciliary neurotrophic factor activates leptin-like pathways and reduces body fat, without cachexia or rebound weight gain, even in leptin-resistant obesity.
Topics: Adipose Tissue; Animals; Cachexia; Ciliary Neurotrophic Factor; Corticosterone; DNA-Binding Proteins | 2001 |
Maternal endotoxemia results in obesity and insulin resistance in adult male offspring.
Topics: Adipose Tissue; Animals; Blood Glucose; Body Composition; Brain Chemistry; Carrier Proteins; Cortico | 2001 |
Prenatal cytokine exposure results in obesity and gender-specific programming.
Topics: Adipose Tissue; Animals; Body Weight; Corticosterone; Cytokines; Dexamethasone; Drug Administration | 2001 |
Transgenic expression of syndecan-1 uncovers a physiological control of feeding behavior by syndecan-3.
Topics: Aging; alpha-MSH; Amino Acid Sequence; Animals; Blood Glucose; Corticosterone; Feeding Behavior; Fem | 2001 |
Modulation of corticosterone availability to white adipose tissue of lean and obese Zucker rats by corticosteroid-binding globulin.
Topics: Adipose Tissue; Aldosterone; Animals; Corticosterone; Dexamethasone; Female; Obesity; Radioimmunoass | 2001 |
A transgenic model of visceral obesity and the metabolic syndrome.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Abdomen; Adipocytes; Adipose Tissue; Animals; Body Comp | 2001 |
Interleukin-6-deficient mice develop mature-onset obesity.
Topics: Age Factors; Animals; Blood Glucose; Body Composition; Corticosterone; Eating; Energy Metabolism; Fe | 2002 |
Cloned mice have an obese phenotype not transmitted to their offspring.
Topics: Adipose Tissue; alpha-MSH; Animals; Body Composition; Body Weight; Cloning, Organism; Corticosterone | 2002 |
Effects of chronic murine and human leptin infusion on plasma leptin and corticosterone levels and energy balance in lean Zucker rats.
Topics: Adipose Tissue, Brown; Animals; Brain; Carrier Proteins; Corticosterone; Energy Metabolism; Epididym | 2001 |
Neuronal activation and corticotropin-releasing hormone expression in the brain of obese (fa/fa) and lean (fa/?) Zucker rats in response to refeeding.
Topics: Animals; Appetite Regulation; Body Weight; Brain; Brain Stem; Corticosterone; Corticotropin-Releasin | 2002 |
Effects of acute and chronic administration of the melanocortin agonist MTII in mice with diet-induced obesity.
Topics: alpha-MSH; Animals; Blood Glucose; Body Weight; Corticosterone; Diet; Eating; Energy Metabolism; Inj | 2002 |
Blockade of body weight gain and plasma corticosterone levels in Zucker fatty rats using an orally active neuropeptide Y Y1 antagonist.
Topics: Adipose Tissue; Administration, Oral; Analysis of Variance; Animals; Appetite Depressants; Cell Size | 2002 |
The effects of high-fat diet on exercise-induced changes in metabolic parameters in Zucker fa/fa rats.
Topics: Animals; Blood Glucose; Body Weight; Cell Separation; Cells, Cultured; Corticosterone; Dietary Fats; | 2002 |
The pituitary-adrenal system of the genetically obese (ob/ob) mouse.
Topics: Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Animals; Body Weight; Circadian Rhythm; C | 1975 |
Some effects of adrenalectomy in the fatty rat.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Animals; Body Weight; Circadian Rhythm; Corticosterone; | 1978 |
Exploratory activity, food intake, brain biochemistry and plasma corticosterone in genetically hypertensive or hypertensive obese rats.
Topics: Animals; Behavior, Animal; Brain Chemistry; Corticosterone; Exploratory Behavior; Feeding Behavior; | 1979 |
Elimination of the hyperlipidemia and proteinuria of genetically obese rats by hypophysectomy.
Topics: Animals; Blood Pressure; Blood Proteins; Blood Urea Nitrogen; Body Weight; Cholesterol; Corticostero | 1979 |
[Rate of cortisol and corticosterone secretion in diabetes mellitus].
Topics: Adult; Corticosterone; Diabetes Mellitus; Female; Humans; Hydrocortisone; Male; Middle Aged; Obesity | 1979 |
Diurnal changes in serum metabolites and hormones in lean and obese Zucker rats.
Topics: Animals; Blood Glucose; Circadian Rhythm; Corticosterone; Growth Hormone; Hormones; Insulin; Obesity | 1978 |
Basal corticosterone levels of young og/ob mice.
Topics: Aging; Animals; Blood Glucose; Corticosterone; Female; Insulin; Male; Mice; Mice, Inbred C57BL; Obes | 1977 |
The influence of age and fasting on serum hormones in the lean and obese-Zucker rat.
Topics: Aging; Animals; Corticosterone; Fasting; Growth Hormone; Hormones; Immunoassay; Obesity; Prolactin; | 1977 |
Effects of limited food intake on the obese-hyperglycemic syndrome.
Topics: Animals; Blood Glucose; Body Composition; Body Height; Body Weight; Bone Development; Corticosterone | 1976 |
Hypothalamic-pituitary-adrenal axis function in the Zucker obese rat.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Animals; Arginine Vasopressin; Corticosterone; Corticotr | 1992 |
Corticosterone and tri-iodothyronine transport into brain of obese (ob/ob) mice.
Topics: Animals; Biological Transport; Blood Proteins; Brain; Corticosterone; Injections, Intra-Arterial; Li | 1992 |
Obese Zucker (fa/fa) rats exhibit normal target sensitivity to corticosterone and increased drive to adrenocorticotropin during the diurnal trough.
Topics: Adipose Tissue; Adrenal Cortex; Adrenalectomy; Adrenocorticotropic Hormone; Animals; Circadian Rhyth | 1992 |
Glucocorticoid receptor numbers in the brain and liver of the obese Zucker rat.
Topics: Animals; Corticosterone; Female; Hippocampus; Hypothalamus; Ligands; Liver; Male; Obesity; Radioimmu | 1992 |
Subchronic treatment with metformin produces anorectic effect and reduces hyperinsulinemia in genetically obese Zucker rats.
Topics: Animals; Appetite Depressants; Blood Glucose; Body Weight; Corticosterone; Digestive System; Eating; | 1992 |
Differential hypothalamic arginine vasopressin response to glucocorticoid receptor antagonism in lean and obese Zucker rats.
Topics: Animals; Arginine Vasopressin; Corticosterone; Hypothalamus; In Situ Hybridization; Male; Median Emi | 1992 |
Studies on nuclear binding of dehydroepiandrosterone in hepatocytes.
Topics: Animals; Cell Nucleus; Corticosterone; Dehydroepiandrosterone; Estrone; Female; Liver; Obesity; Rats | 1992 |
Relationships between lipid availability and protein utilization during prolonged fasting.
Topics: Adaptation, Physiological; Adipose Tissue; Animals; Body Weight; Corticosterone; Energy Metabolism; | 1992 |
Is there a role for the adrenals in the development of hypercholesterolemia in Zucker fatty rats?
Topics: Adipose Tissue; Adrenal Glands; Adrenalectomy; Animals; Body Weight; Corticosterone; Eating; Hyperch | 1992 |
The glucocorticoid antagonist mifepristone reveals abnormal regulation of the adrenocortical system in obese Zucker rats.
Topics: Animals; Corticosterone; Corticotropin-Releasing Hormone; Hypothalamo-Hypophyseal System; Male; Mife | 1992 |
Mifepristone (RU 486), a blocker of type II glucocorticoid and progestin receptors, reverses a dietary form of obesity.
Topics: Animals; Corticosterone; Dietary Fats; Female; Mifepristone; Obesity; Rats; Rats, Mutant Strains; Re | 1992 |
Sustained decreases in weight and serum insulin, glucose, triacylglycerol and cholesterol in JCR:LA-corpulent rats treated with D-fenfluramine.
Topics: Adipose Tissue; Aging; Animals; Blood Glucose; Body Weight; Cholesterol; Corticosterone; Eating; Fat | 1992 |
Paraventricular hypothalamic obesity in rats: role of corticosterone.
Topics: Adrenalectomy; Animals; Blood Glucose; Body Weight; Corticosterone; Female; Histocytochemistry; Insu | 1992 |
Effects of repeated administration of mifepristone and 8-OH-DPAT on expression of preproneuropeptide Y mRNA in the arcuate nucleus of obese Zucker rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Arcuate Nucleus of Hypothalamus; Corticosterone; Ge | 1991 |
Altered neuropeptide Y concentrations in specific hypothalamic regions of obese (fa/fa) Zucker rats. Possible relationship to obesity and neuroendocrine disturbances.
Topics: Adrenocorticotropic Hormone; Animal Nutritional Physiological Phenomena; Animals; Arcuate Nucleus of | 1991 |
Aspects of neuroregulation of body composition and insulin secretion.
Topics: Adipose Tissue; Adipose Tissue, Brown; Adrenocorticotropic Hormone; Animals; Autonomic Nervous Syste | 1991 |
Adrenalectomy in the Zucker fatty rat: effect on m-RNA for malic enzyme and glyceraldehyde 3-phosphate dehydrogenase.
Topics: Adipose Tissue; Adrenal Glands; Adrenalectomy; Animals; Body Weight; Corticosterone; Densitometry; D | 1991 |
Influence of genetic obesity, dietary carbohydrate and age on parameters of glucose tolerance and kidney and adrenal gland histology in female SHR/N-corpulent rats.
Topics: Adrenal Cortex; Animals; Blood Glucose; Corticosterone; Dietary Carbohydrates; Female; Glomerular Me | 1990 |
Effects of antiglucocorticoid RU 486 on development of obesity in obese fa/fa Zucker rats.
Topics: Animals; Body Composition; Body Weight; Brain; Corticosterone; Eating; Female; Glucocorticoids; Insu | 1990 |
Increased type II glucocorticoid-receptor numbers and glucocorticoid-sensitive enzyme activities in the brain of the obese Zucker rat.
Topics: Adrenal Glands; Adrenalectomy; Animals; Brain; Corticosterone; Female; Glutamate Synthase; Glycerolp | 1990 |
Long-term actions of d-fenfluramine in two rat models of obesity. II. Responses to stress.
Topics: Animals; Body Weight; Brain Chemistry; Cold Temperature; Corticosterone; Female; Fenfluramine; Obesi | 1990 |
Abnormal regulation of the hypothalamo-pituitary-adrenal axis in the genetically obese fa/fa rat.
Topics: Animals; Circadian Rhythm; Cold Temperature; Corticosterone; Dexamethasone; Ether; Female; Hypothala | 1990 |
Brain 3-hydroxybutyrate, glutamate, and GABA in a rat model of dietary obesity.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Brain; Brain Chemistry; Corticosterone; Dietary Fats; | 1989 |
The metabolic clearance rate of corticosterone in lean and obese male Zucker rats.
Topics: Animals; Bile; Body Weight; Circadian Rhythm; Corticosterone; Metabolic Clearance Rate; Obesity; Rat | 1989 |
Hormonal studies of young lean and obese Zucker rats.
Topics: Animals; Blood Glucose; Corticosterone; Fasting; Female; Hormones; Insulin; Obesity; Pancreas; Rats; | 1986 |
Effects of adrenalectomy before weaning and short- or long-term glucocorticoid administration on the genetically obese Zucker rat.
Topics: Acetyl-CoA Carboxylase; Adrenalectomy; Animals; Blood Glucose; Corticosterone; Fatty Acids; Insulin; | 1986 |
Comparative hormonal profile of two newly developed obese congenic rat strains.
Topics: Animals; Corticosterone; Dietary Carbohydrates; Glucagon; Growth Hormone; Hormones; Insulin; Male; O | 1988 |
Adrenal glucocorticoids regulate adipsin gene expression in genetically obese mice.
Topics: Adipose Tissue; Adrenalectomy; Animals; Cell Line; Complement Factor D; Corticosterone; Cricetinae; | 1989 |
Regulation of brown adipose tissue thermogenesis by corticosterone in obese fa/fa rats.
Topics: Adipose Tissue, Brown; Adrenalectomy; Aldosterone; Animals; Body Temperature Regulation; Body Weight | 1985 |
Hypercorticosteronuria and diminished pituitary responsiveness to corticotropin-releasing factor in obese Zucker rats.
Topics: Animals; beta-Endorphin; Corticosterone; Corticotropin-Releasing Hormone; Dexamethasone; Endorphins; | 1986 |
Anti-opiate (naloxone) suppression of Cushingoid degenerative changes in obese/SHR.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; beta-Endorphin; Blood Pressure; Body Weight; C | 1985 |
Hypothalamic obesity after hypophysectomy or adrenalectomy: dependence on corticosterone.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Animals; Body Weight; Corticosterone; Female; Hypophysec | 1985 |
Diet-induced type II diabetes in C57BL/6J mice.
Topics: Animals; Blood Glucose; Corticosterone; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; | 1988 |
The parasympathetic nervous system and glucocorticoid-mediated hyperinsulinaemia in the genetically obese (fa/fa) Zucker rat.
Topics: Adrenalectomy; Animals; Atropine; Blood Glucose; Corticosterone; Insulin; Obesity; Parasympathetic N | 1988 |
Food restriction normalizes somatic growth and diabetes in adrenalectomized ob/ob mice.
Topics: Adrenalectomy; Animals; Blood Glucose; Body Composition; Body Temperature Regulation; Corticosterone | 1988 |
Central nervous system control of hyperphagia in hypothalamic obesity: dependence on adrenal glucocorticoids.
Topics: Adrenal Glands; Adrenalectomy; Animals; Aurothioglucose; Body Weight; Corticosterone; Cortisone; Dex | 1986 |
Anorexia after adrenalectomy in gold thioglucose-treated obese mice: role of adipose tissue mass.
Topics: Adipose Tissue; Adrenalectomy; Animals; Anorexia; Aurothioglucose; Blood Glucose; Corticosterone; Fe | 1986 |
Diminished glucocorticoid tonus in obese strain (OS) chickens with spontaneous autoimmune thyroiditis: increased plasma levels of a physicochemically unaltered corticosteroid-binding globulin but normal total corticosterone plasma concentration and normal
Topics: Animals; Chickens; Corticosterone; Glucocorticoids; Obesity; Receptors, Glucocorticoid; Species Spec | 1988 |
Dynamic and static phases of obesity following lesions in PVN and VMH.
Topics: Adipose Tissue, Brown; Animals; Body Weight; Circadian Rhythm; Corticosterone; Energy Intake; Female | 1987 |
Responsiveness of isolated adrenocortical cells from lean and obese Zucker rats to ACTH.
Topics: Adrenal Cortex; Animals; Corticosterone; Cosyntropin; DNA; Dose-Response Relationship, Drug; Female; | 1988 |
Normal levels of serum corticosterone and hepatic glucocorticoid receptors in obese (fa/fa) rats.
Topics: Adrenalectomy; Animals; Corticosterone; Female; Heterozygote; Homozygote; Liver; Obesity; Rats; Rats | 1987 |
Elevation of corticosteroid-binding globulin in obese strain (OS) chickens: possible implications for the disturbed immunoregulation and the development of spontaneous autoimmune thyroiditis.
Topics: Animals; Chickens; Corticosterone; Hydrocortisone; Lymphocyte Activation; Obesity; Spleen; T-Lymphoc | 1986 |
Effects on growth and endocrine status of maintaining obese and lean Zucker rats at 22 degrees C and 30 degrees C from weaning.
Topics: Animals; Body Temperature Regulation; Corticosterone; Female; Growth; Hormones; Insulin; Obesity; Ra | 1986 |
Increased sensitivity of the genetically obese mouse to corticosterone.
Topics: Adipose Tissue; Adipose Tissue, Brown; Adrenalectomy; Animals; Blood Glucose; Body Temperature; Body | 1987 |
Deprivation of corticosterone does not prevent onset of obesity in Zucker fa/fa pups.
Topics: Adipose Tissue; Adipose Tissue, Brown; Adrenalectomy; Animals; Body Temperature Regulation; Corticos | 1987 |
Genetically obese (ob/ob) mice are hypersensitive to glucocorticoid stimulation of feeding but dramatically resist glucocorticoid-induced weight loss.
Topics: Animals; Body Weight; Corticosterone; Dexamethasone; Dose-Response Relationship, Drug; Feeding Behav | 1987 |
Effects of adrenalectomy on energy balance in obese (ob/ob) mice fed high carbohydrate or high fat diets.
Topics: Adrenalectomy; Animals; Blood Glucose; Corticosterone; Dietary Carbohydrates; Dietary Fats; Energy M | 1987 |
Disturbed immune-endocrine communication in autoimmune disease. Lack of corticosterone response to immune signals in obese strain chickens with spontaneous autoimmune thyroiditis.
Topics: Animals; Chickens; Corticosterone; Immunization; Lymphocyte Activation; Lymphokines; Obesity; Thyroi | 1987 |
Effects of adrenalectomy before weaning in the genetically obese Zucker rat (fa/fa).
Topics: Adrenalectomy; Animals; Corticosterone; Injections; Lipid Metabolism; Obesity; Phenotype; Proteins; | 1986 |
The effects of 2-deoxy-D-glucose on brown adipose tissue of lean and obese Zucker rats.
Topics: Adipose Tissue, Brown; Animals; Blood Glucose; Body Temperature Regulation; Corticosterone; Deoxy Su | 1986 |
Effect of adrenalectomy and corticosterone replacement on meal patterns of Zucker rats.
Topics: Adrenalectomy; Animals; Body Weight; Corticosterone; Drinking; Eating; Feeding Behavior; Male; Obesi | 1985 |
[Corticosterone secretion in man. II. Relation to body weight and body surface. Comparison to cortisol secretion].
Topics: Adrenocorticotropic Hormone; Body Height; Body Weight; Corticosterone; Humans; Hydrocortisone; Obesi | 1965 |
[Mutual relations between adrenal gland hormones and lipid metabolism].
Topics: Adipose Tissue; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Animals; Carbohydrate Metaboli | 1972 |
[Membrane adenyl cyclase activity in adipose tissue of obese hyperglycemic Bar-Harbor mice].
Topics: Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Blood Glucose; Cell Membran | 1973 |
In vitro release of corticosteroids from adrenal glands of obese-hyperglycemic mice (gene symbol ob).
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Age Factors; Animals; Carbon Dioxide; Corticosterone; C | 1974 |
Excretion of individual adrenocortical steroids in obese children.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Age Determination b | 1974 |
Function of the adrenal cortex in obese-hyperglycemic mice (gene symbol ob).
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Age Factors; Animals; Blood Gl | 1974 |
Serum growth hormone levels following ablation of medial basal hypothalamus.
Topics: Animals; Body Weight; Corticosterone; Ethers; Growth Hormone; Hypothalamus; Male; Obesity; Radioimmu | 1974 |
Effects of adrenalectomy on the obese-hyperglycemic syndrome in mice (gene symbol ob).
Topics: Adrenal Glands; Adrenalectomy; Animals; Blood Glucose; Body Weight; Corticosterone; Diet; Genes, Rec | 1973 |
[New method for the determination of 7 fractions of 17-deoxycorticosteroid (DOC, Comp. B, Comp. A, allo THB, THB, THA and aldosterone) and their urinary excretion. 2. Urinary excretion during normal menstrual cycle and in patients with various disease].
Topics: 17-Hydroxycorticosteroids; Acromegaly; Adult; Aldosterone; Androgen-Insensitivity Syndrome; Collagen | 1972 |
Temporal synergism of corticosterone and prolactin controlling fat storage in the white-throated sparrow, Zonotrichia albicollis.
Topics: Adipose Tissue; Animals; Birds; Circadian Rhythm; Corticosterone; Drug Synergism; Light; Lipid Metab | 1971 |
Genetic regulation of plasma corticosterone concentration and its response to castration and allogeneic tumour growth in the mouse.
Topics: Animals; Castration; Corticosterone; Fluorometry; Genetics; Genotype; Insulin; Male; Mice; Obesity; | 1971 |
Selective lack of response of corticosterone to dexamethasone suppression in some obese subjects with asymptomatic diabetes mellitus.
Topics: Corticosterone; Dexamethasone; Diabetes Mellitus; Humans; Hydrocortisone; Obesity | 1971 |
Glycolytic and gluconeogenic metabolites and enzymes in the liver of obese-hyperglycemic mice (KK) and alloxan diabetic mice.
Topics: Animals; Blood Glucose; Body Weight; Corticosterone; Diabetes Mellitus, Experimental; Fatty Acids; G | 1969 |
[Changed circadian rhythm of cortisol excretion in obese children].
Topics: Age Factors; Child; Circadian Rhythm; Corticosterone; Fluorometry; Humans; Hydrocortisone; Obesity | 1967 |
[Effects of protracted fasting on the adrenocortical function in obesity].
Topics: 17-Ketosteroids; Adolescent; Adrenal Glands; Adult; Corticosterone; Fasting; Female; Humans; Male; M | 1967 |
Adrenocortical indices during fasting in obesity.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Glands; Adult; Body Weight; Corticos | 1969 |
[Fluorimetric determination of free plasma 11-hydroxycorticoids (cortisol and corticosterone), for rapid evaluation of the adrenal glycocorticoid activity].
Topics: Addison Disease; Adrenal Insufficiency; Blood; Corticosterone; Cushing Syndrome; Dexamethasone; Fema | 1965 |