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corticosterone and Muscular Atrophy

corticosterone has been researched along with Muscular Atrophy in 31 studies

Muscular Atrophy: Derangement in size and number of muscle fibers occurring with aging, reduction in blood supply, or following immobilization, prolonged weightlessness, malnutrition, and particularly in denervation.

Research Excerpts

ExcerptRelevanceReference
"TNF-tg and wild-type (WT) animals received either vehicle or the GC corticosterone (100 μg/ml) in drinking water at onset of arthritis."3.91Therapeutic glucocorticoids prevent bone loss but drive muscle wasting when administered in chronic polyarthritis. ( Cooper, MS; Fareed, S; Fenton, CG; Goodyear, CS; Hardy, RS; Jones, R; Jones, SW; Lai, YC; Langen, R; Lavery, GG; Lewis, JW; Mackie, H; Martin, CS; Raza, K; Seabright, AP; Webster, JM; Wehmeyer, C, 2019)
" The purpose of this study was to elucidate whether administration of a β2 adrenergic agonist, formoterol, was able to prevent the acute effects of sepsis induced by liposaccharide (LPS) injection on rat gastrocnemius muscle and to evaluate the possible roles of corticosterone, IGF-I, miR-23a, and miR-29b."3.88Formoterol treatment prevents the effects of endotoxin on muscle TNF/NF-kB, Akt/mTOR, and proteolytic pathways in a rat model. Role of IGF-I and miRNA 29b. ( Gómez-SanMiguel, AB; López-Calderón, A; Martín, AI; Priego, T, 2018)
" To identify signals that activate this system, we studied acutely diabetic rats that had metabolic acidosis and increased corticosterone production."3.70Evaluation of signals activating ubiquitin-proteasome proteolysis in a model of muscle wasting. ( Bailey, JL; Jurkovitz, C; Mitch, WE; Newby, D; Price, SR; Wang, X, 1999)
"Hypoxia induces skeletal muscle atrophy in mice, which can in part be attributed to reduced food intake."1.48Glucocorticoid Receptor Signaling Impairs Protein Turnover Regulation in Hypoxia-Induced Muscle Atrophy in Male Mice. ( Ceelen, JJM; de Theije, CC; Hermans, JJR; Köhler, SE; Lamers, WH; Langen, RCJ; Schols, AMWJ; van Gorp, RH, 2018)
"Arthritis was induced in male Wistar rats by intradermal injection of Freund's adjuvant."1.46Melanocortin-4 receptor agonist (RO27-3225) ameliorates soleus but not gastrocnemius atrophy in arthritic rats. ( Fernandez-Galaz, C; Gomez-Sanmiguel, AB; Lopez-Calderon, A; Martin, AI; Nieto-Bona, MP; Priego, T, 2017)
"After sleep deprivation, GA muscle and body masses decreased in the SD group compared to the CTL, LEU, and LEU + SD groups."1.43Leucine supplementation is anti-atrophic during paradoxical sleep deprivation in rats. ( Antunes, HKM; Dáttilo, M; de Campos Giampa, SQ; de Mello, MT; de Sá Souza, H; Lee, KS; Mônico-Neto, M; Phillips, SM; Tufik, S, 2016)
"While skeletal muscle atrophy and resultant myopathy is a clinical feature, the molecular mechanisms underpinning these changes are not fully defined."1.43Glucocorticoids and 11β-HSD1 are major regulators of intramyocellular protein metabolism. ( Doig, CL; Hassan-Smith, ZK; Lavery, GG; Morgan, SA; Sherlock, M; Stewart, PM, 2016)
"Corticosterone was increased in the SD group compared with the control group, and this increase was minimized in the RT+SD group."1.42Resistance training minimizes catabolic effects induced by sleep deprivation in rats. ( Antunes, HK; Dáttilo, M; de Mello, MT; de Moraes, WM; Giampá, SQ; Lee, KS; Medeiros, A; Mônico-Neto, M; Phillips, SM; Souza, Hde S; Tufik, S, 2015)
"Cancer cachexia is a syndrome of weight loss that results from the selective depletion of skeletal muscle mass and contributes significantly to cancer morbidity and mortality."1.40Muscle atrophy in response to cytotoxic chemotherapy is dependent on intact glucocorticoid signaling in skeletal muscle. ( Agarwal, A; Braun, TP; Grossberg, AJ; Levasseur, PR; Marks, DL; Szumowski, M; Zhu, X, 2014)
"3."1.28Effects of a beta 2-adrenergic agonist, cimaterol and corticosterone on growth and carcass composition of male rats. ( Brown, J; Clasper, C; Lomax, MA; Smith, T, 1992)
"Hindlimb muscle atrophy, thymic involution and adrenal hypertrophy in rats during spaceflight can be simulated using suspension models."1.27Thymic involution in the suspended rat model for weightlessness: decreased glucocorticoid receptor concentration. ( Musacchia, XJ; Steffen, JM, 1984)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19903 (9.68)18.7374
1990's4 (12.90)18.2507
2000's4 (12.90)29.6817
2010's17 (54.84)24.3611
2020's3 (9.68)2.80

Authors

AuthorsStudies
Li, S1
Schönke, M1
Buurstede, JC1
Moll, TJA1
Gentenaar, M1
Schilperoort, M1
Visser, JA1
Kaikaew, K1
van de Vijver, D1
Abbassi-Daloii, T1
Raz, V1
Aartsma-Rus, A1
van Putten, M1
Meijer, OC1
Kroon, J1
Yamazaki, H1
Uehara, M1
Yoshikawa, N1
Kuribara-Souta, A1
Yamamoto, M1
Hirakawa, Y1
Kabe, Y1
Suematsu, M1
Tanaka, H1
Karnia, MJ1
Myślińska, D1
Dzik, KP1
Flis, DJ1
Podlacha, M1
Kaczor, JJ1
Gomez-Sanmiguel, AB2
Nieto-Bona, MP1
Fernandez-Galaz, C1
Priego, T2
Martin, AI2
Lopez-Calderon, A2
Cai, X1
Yuan, Y1
Liao, Z1
Xing, K1
Zhu, C1
Xu, Y1
Yu, L1
Wang, L1
Wang, S1
Zhu, X3
Gao, P1
Zhang, Y1
Jiang, Q1
Xu, P1
Shu, G1
de Theije, CC1
Schols, AMWJ1
Lamers, WH1
Ceelen, JJM1
van Gorp, RH1
Hermans, JJR1
Köhler, SE1
Langen, RCJ1
Fenton, CG1
Webster, JM1
Martin, CS1
Fareed, S1
Wehmeyer, C1
Mackie, H1
Jones, R1
Seabright, AP1
Lewis, JW1
Lai, YC1
Goodyear, CS1
Jones, SW1
Cooper, MS1
Lavery, GG2
Langen, R1
Raza, K1
Hardy, RS1
Braun, TP2
Szumowski, M2
Levasseur, PR2
Grossberg, AJ2
Agarwal, A1
Marks, DL2
Britto, FA1
Begue, G1
Rossano, B1
Docquier, A1
Vernus, B1
Sar, C1
Ferry, A1
Bonnieu, A1
Ollendorff, V1
Favier, FB1
Beaudry, JL2
Dunford, EC1
Leclair, E1
Mandel, ER1
Peckett, AJ1
Haas, TL1
Riddell, MC2
Egawa, T1
Goto, A1
Ohno, Y1
Yokoyama, S1
Ikuta, A1
Suzuki, M1
Sugiura, T1
Ohira, Y1
Yoshioka, T1
Hayashi, T1
Goto, K1
Mônico-Neto, M2
Antunes, HK1
Lee, KS2
Phillips, SM2
Giampá, SQ1
Souza, Hde S1
Dáttilo, M2
Medeiros, A1
de Moraes, WM1
Tufik, S2
de Mello, MT2
de Sá Souza, H1
Antunes, HKM1
de Campos Giampa, SQ1
Morgan, SA1
Hassan-Smith, ZK1
Doig, CL1
Sherlock, M1
Stewart, PM1
Duan, K1
Chen, Q1
Cheng, M1
Zhao, C1
Lin, Z1
Tan, S1
Xi, F1
Gao, T1
Shi, J1
Shen, J1
Li, W1
Yu, W1
Li, J1
Li, N1
Menconi, M1
Gonnella, P1
Petkova, V1
Lecker, S1
Hasselgren, PO1
Allen, DL2
McCall, GE1
Loh, AS2
Madden, MC1
Mehan, RS1
Cleary, AS1
Lindsay, SF1
Reed, JM1
Scott, GD1
Graham, K1
Khan, S1
Damaraju, S1
Colmers, WF1
Baracos, VE1
Shpilberg, Y1
D'Souza, A1
Campbell, JE1
Peckett, A1
Kanda, K2
Omori, S1
Yamamoto, C1
Miyamoto, N1
Kawano, S2
Murata, Y2
Matsui, N1
Seo, H2
Ohmori, S1
Ito, T1
Björkqvist, M1
Petersén, A1
Bacos, K1
Isaacs, J1
Norlén, P1
Gil, J1
Popovic, N1
Sundler, F1
Bates, GP1
Tabrizi, SJ1
Brundin, P1
Mulder, H1
Mitch, WE1
Bailey, JL1
Wang, X1
Jurkovitz, C1
Newby, D1
Price, SR1
Harjola, V1
Jänkälä, H2
Härkönen, M2
Harjola, VP1
Steffen, JM2
Musacchia, XJ2
Tischler, ME1
Henriksen, EJ1
Jaspers, SR1
Jacob, S1
Kirby, C1
Brown, J1
Clasper, C1
Smith, T1
Lomax, MA1

Other Studies

31 other studies available for corticosterone and Muscular Atrophy

ArticleYear
Sexual Dimorphism in Transcriptional and Functional Glucocorticoid Effects on Mouse Skeletal Muscle.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Androgens; Animals; Corticosterone; Female; Glucocorticoids; Humans; Male; Mice; Muscle, Skeletal; M

2022
The crucial role of muscle glucocorticoid signaling in accelerating obesity and glucose intolerance via hyperinsulinemia.
    JCI insight, 2023, 04-24, Volume: 8, Issue:8

    Topics: Animals; Corticosterone; Diabetes Mellitus; Glucocorticoids; Glucose Intolerance; Hyperinsulinism; M

2023
BST Stimulation Induces Atrophy and Changes in Aerobic Energy Metabolism in Rat Skeletal Muscles-The Biphasic Action of Endogenous Glucocorticoids.
    International journal of molecular sciences, 2020, Apr-17, Volume: 21, Issue:8

    Topics: Aerobiosis; Animals; Cell Respiration; Corticosterone; Electric Stimulation; Energy Metabolism; Fibr

2020
Melanocortin-4 receptor agonist (RO27-3225) ameliorates soleus but not gastrocnemius atrophy in arthritic rats.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2017, Volume: 68, Issue:2

    Topics: Adrenocorticotropic Hormone; Animals; Anti-Inflammatory Agents; Arthritis; Corticosterone; Cyclooxyg

2017
α-Ketoglutarate prevents skeletal muscle protein degradation and muscle atrophy through PHD3/ADRB2 pathway.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2018, Volume: 32, Issue:1

    Topics: Animals; Corticosterone; Disease Models, Animal; Ketoglutaric Acids; Male; Metabolic Networks and Pa

2018
Glucocorticoid Receptor Signaling Impairs Protein Turnover Regulation in Hypoxia-Induced Muscle Atrophy in Male Mice.
    Endocrinology, 2018, 01-01, Volume: 159, Issue:1

    Topics: Animals; Autophagy; Cell Size; Corticosterone; Crosses, Genetic; Gene Expression Regulation, Enzymol

2018
Formoterol treatment prevents the effects of endotoxin on muscle TNF/NF-kB, Akt/mTOR, and proteolytic pathways in a rat model. Role of IGF-I and miRNA 29b.
    American journal of physiology. Endocrinology and metabolism, 2018, 10-01, Volume: 315, Issue:4

    Topics: Adrenergic beta-2 Receptor Agonists; Animals; Corticosterone; Formoterol Fumarate; Insulin-Like Grow

2018
Therapeutic glucocorticoids prevent bone loss but drive muscle wasting when administered in chronic polyarthritis.
    Arthritis research & therapy, 2019, 08-01, Volume: 21, Issue:1

    Topics: Animals; Arthritis; Biopsy; Bone Resorption; Cells, Cultured; Chronic Disease; Corticosterone; Disea

2019
Muscle atrophy in response to cytotoxic chemotherapy is dependent on intact glucocorticoid signaling in skeletal muscle.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagy; Cachexia; Corticosterone; Female; Gene Knockou

2014
REDD1 deletion prevents dexamethasone-induced skeletal muscle atrophy.
    American journal of physiology. Endocrinology and metabolism, 2014, Dec-01, Volume: 307, Issue:11

    Topics: Animals; Corticosterone; Dexamethasone; Feces; Female; Mice; Muscle Contraction; Muscle, Skeletal; M

2014
Voluntary exercise improves metabolic profile in high-fat fed glucocorticoid-treated rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 2015, Jun-01, Volume: 118, Issue:11

    Topics: Adiposity; Animals; Behavior, Animal; Biomarkers; Blood Glucose; Body Weight; Corticosterone; Diabet

2015
Involvement of AMPK in regulating slow-twitch muscle atrophy during hindlimb unloading in mice.
    American journal of physiology. Endocrinology and metabolism, 2015, Oct-01, Volume: 309, Issue:7

    Topics: AMP-Activated Protein Kinases; Animals; Corticosterone; Genes, Dominant; Hindlimb Suspension; Male;

2015
Resistance training minimizes catabolic effects induced by sleep deprivation in rats.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2015, Volume: 40, Issue:11

    Topics: Animals; Autophagy; Corticosterone; Disease Models, Animal; Insulin-Like Growth Factor I; Male; Musc

2015
Leucine supplementation is anti-atrophic during paradoxical sleep deprivation in rats.
    Amino acids, 2016, Volume: 48, Issue:4

    Topics: Administration, Oral; Animals; Carrier Proteins; Corticosterone; Dietary Supplements; Gene Expressio

2016
Glucocorticoids and 11β-HSD1 are major regulators of intramyocellular protein metabolism.
    The Journal of endocrinology, 2016, Volume: 229, Issue:3

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Cell Line; Cell Proliferation; Cells, Cultured

2016
Hypothalamic activation is essential for endotoxemia-induced acute muscle wasting.
    Scientific reports, 2016, 12-06, Volume: 6

    Topics: Acute Disease; Animals; Corticosterone; Cytokines; Endotoxemia; Gene Knockdown Techniques; Hypothala

2016
Dexamethasone and corticosterone induce similar, but not identical, muscle wasting responses in cultured L6 and C2C12 myotubes.
    Journal of cellular biochemistry, 2008, Oct-01, Volume: 105, Issue:2

    Topics: Animals; Cell Line; Corticosterone; Dexamethasone; Dose-Response Relationship, Drug; Gene Expression

2008
Acute daily psychological stress causes increased atrophic gene expression and myostatin-dependent muscle atrophy.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2010, Volume: 299, Issue:3

    Topics: Animals; Corticosterone; Gene Expression Regulation; Mice; Muscle, Skeletal; Muscular Atrophy; Myost

2010
Myostatin expression is increased by food deprivation in a muscle-specific manner and contributes to muscle atrophy during prolonged food deprivation in mice.
    Journal of applied physiology (Bethesda, Md. : 1985), 2010, Volume: 109, Issue:3

    Topics: Animals; Blood Glucose; Corticosterone; Eating; Food Deprivation; Glucokinase; Gluconeogenesis; Male

2010
Central nervous system inflammation induces muscle atrophy via activation of the hypothalamic-pituitary-adrenal axis.
    The Journal of experimental medicine, 2011, Nov-21, Volume: 208, Issue:12

    Topics: Adrenalectomy; Analysis of Variance; Animals; Blotting, Western; Central Nervous System; Corticoster

2011
A rodent model of rapid-onset diabetes induced by glucocorticoids and high-fat feeding.
    Disease models & mechanisms, 2012, Volume: 5, Issue:5

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipose Tissue; Adiposity; Animals; Body Composition; C

2012
Urinary excretion of stress hormones of rats in tail-suspension.
    Environmental medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University, 1993, Volume: 37, Issue:1

    Topics: Adrenal Glands; Animals; Body Weight; Corticosterone; Epinephrine; Hindlimb Suspension; Male; Muscul

1993
Adrenocortical response to tail-suspension in young and old rats.
    Environmental medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University, 1994, Volume: 38, Issue:1

    Topics: Adaptation, Physiological; Adrenal Glands; Age Factors; Aging; Animals; Body Weight; Corticosterone;

1994
Progressive alterations in the hypothalamic-pituitary-adrenal axis in the R6/2 transgenic mouse model of Huntington's disease.
    Human molecular genetics, 2006, May-15, Volume: 15, Issue:10

    Topics: Adrenocorticotropic Hormone; Adult; Animals; Body Fat Distribution; Bone Density; Corticosterone; Di

2006
Evaluation of signals activating ubiquitin-proteasome proteolysis in a model of muscle wasting.
    The American journal of physiology, 1999, Volume: 276, Issue:5

    Topics: Acidosis; Adrenalectomy; Animals; Corticosterone; Cysteine Endopeptidases; Dexamethasone; Diabetes M

1999
Myosin heavy chain mRNA and protein distribution in immobilized rat skeletal muscle are not affected by testosterone status.
    Acta physiologica Scandinavica, 2000, Volume: 169, Issue:4

    Topics: Animals; Body Weight; Corticosterone; Immobilization; Male; Muscle, Skeletal; Muscular Atrophy; Myos

2000
The effect of androgen status on skeletal muscle myosin heavy chain mRNA and protein levels in rats recovering from immobilization.
    European journal of applied physiology, 2000, Volume: 83, Issue:4 -5

    Topics: Androgens; Animals; Body Weight; Corticosterone; Hindlimb Suspension; Male; Muscle, Skeletal; Muscul

2000
Thymic involution in the suspended rat model for weightlessness: decreased glucocorticoid receptor concentration.
    The Physiologist, 1984, Volume: 27, Issue:6 Suppl

    Topics: Animals; Atrophy; Corticosterone; Dexamethasone; Hindlimb Suspension; Male; Muscle, Skeletal; Muscul

1984
Changes in muscles accompanying non-weight-bearing and weightlessness.
    Advances in myochemistry, 1989, Volume: 2

    Topics: Ammonium Chloride; Animals; Body Weight; Corticosterone; Female; Glucose; Glycogen; Hindlimb Suspens

1989
Effects of a beta 2-adrenergic agonist, cimaterol and corticosterone on growth and carcass composition of male rats.
    Comparative biochemistry and physiology. Comparative physiology, 1992, Volume: 102, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Body Composition; Corticosterone; Ethanolamines; Growth; Male; Mu

1992
Disuse atrophy, plasma corticosterone, and muscle glucocorticoid receptor levels.
    Aviation, space, and environmental medicine, 1987, Volume: 58, Issue:10

    Topics: Animals; Corticosterone; Dexamethasone; Hindlimb; Liver; Male; Muscles; Muscular Atrophy; Myocardium

1987