Page last updated: 2024-11-06

corticosterone and Insulin Resistance

corticosterone has been researched along with Insulin Resistance in 131 studies

Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.

Research Excerpts

ExcerptRelevanceReference
" However, in VAT, GCs induce DNL, higher palmitic acid (PA), macrophage infiltration, and proinflammatory cytokine levels, accompanied by systemic nonesterified fatty acid (NEFA) elevation, hyperinsulinemia, and higher homeostatic model assessment for insulin resistance (HOMA-IR) levels compared with diet-induced obesity."7.96Long-term hypercortisolism induces lipogenesis promoting palmitic acid accumulation and inflammation in visceral adipose tissue compared with HFD-induced obesity. ( García-Eguren, G; Giró, O; Hanzu, FA; Sala-Vila, A; Vega-Beyhart, A, 2020)
" Ursolic acid, metformin, gliclazide and their combinations when administered daily for 30 days significantly improved insulin sensitivity apart from behavioral and biochemical alterations in stressed mice."7.88Synergistic action of ursolic acid and metformin in experimental model of insulin resistance and related behavioral alterations. ( Ahuja, S; Akhtar, A; Kumar, A; Mourya, A; Sah, SP, 2018)
"We hypothesized that nicotine would ameliorate insulin resistance (IR) that is accompanied by decreased cardiac glycogen synthase kinase-3 (GSK-3) and plasminogen activator inhibitor-1 (PAI-1)."7.88Ameliorative effect of nicotine exposure on insulin resistance is accompanied by decreased cardiac glycogen synthase kinase-3 and plasminogen activator inhibitor-1 during oral oestrogen-progestin therapy. ( Michael, OS; Olatunji, LA, 2018)
"COC treatment or nicotine exposure led to increased insulin resistance (IR), hemorheological (blood viscosity, hematocrit and plasma viscosity), prothrombotic (plasminogen activator inhibitor-1), pro-inflammatory (uric acid, C-reactive protein, neutrophil/lymphocyte and platelet/lymphocyte ratios) biomarkers and corticosterone."7.85Anti-inflammatory and antithrombotic effects of nicotine exposure in oral contraceptive-induced insulin resistance are glucocorticoid-independent. ( Adeyanju, OA; Areola, ED; Michael, OS; Olatunji, LA; Soladoye, AO, 2017)
" Herein, we have described a mouse model of a depression-like and insulin-resistant (DIR) state induced by the co-treatment of high-fat diet (HFD) and corticosterone (CORT)."7.80Depression-like behaviors in mice subjected to co-treatment of high-fat diet and corticosterone are ameliorated by AICAR and exercise. ( Ji, L; Li, H; Liu, W; Zhai, X, 2014)
" The first experiment was conducted to determine the effects of lipoic acid (ALA; 200 mg/kg) on plasma lipids and insulin sensitivity of whole-body tissue in broilers treated with or without corticosterone (5 mg/kg)."7.73Effects of dietary lipoic acid on plasma lipid, in vivo insulin sensitivity, metabolic response to corticosterone and in vitro lipolysis in broiler chickens. ( Hamano, Y, 2006)
"2."6.73Corticosterone administration and high-energy feed results in enhanced fat accumulation and insulin resistance in broiler chickens. ( Jiang, KJ; Jiao, HC; Lin, H; Song, ZG; Yuan, L, 2008)
"Corticosterone treatment increased adipose tissue mass in both sexes, which was reflected by elevated serum leptin levels."5.51Sex Difference in Corticosterone-Induced Insulin Resistance in Mice. ( Grefhorst, A; Kaikaew, K; Steenbergen, J; van Dijk, TH; Visser, JA, 2019)
"Insulin resistance has been identified as the key mechanism linking depression and diabetes."5.46Curcumin reverses the depressive-like behavior and insulin resistance induced by chronic mild stress. ( Li, YC; Li, YJ; Qiao, JY; Shen, JD; Wei, Y, 2017)
"Chronic stress or long-term administration of glucocorticoids disrupts the hypothalamus-pituitary-adrenal system leading to continuous high levels of glucocorticoids and insulin resistance (IR)."5.40Long-term corticosterone exposure decreases insulin sensitivity and induces depressive-like behaviour in the C57BL/6NCrl mouse. ( Blokland, A; Cañete, R; Pawluski, JL; Sierksma, AS; Steinbusch, HW; Vaessen, KR; van Donkelaar, EL, 2014)
"Propranolol is a β-adrenergic antagonist commonly used in the treatment of hypertension or acute anxiety."5.39Propranolol reduces cognitive deficits, amyloid β levels, tau phosphorylation and insulin resistance in response to chronic corticosterone administration. ( Aguirre, N; Dobarro, M; Orejana, L; Ramírez, MJ, 2013)
"Corticosterone treatment induced an increased expression of stress-activated c-Jun N-terminal kinase (JNK) in the hippocampus, accompanied by decreases in glycogen synthase kinase 3β, increases in pTau levels and increased neuronal cell death (caspase-3 activity)."5.39Mineralocorticoid receptor activation induces insulin resistance through c-Jun N-terminal kinases in response to chronic corticosterone: cognitive implications. ( Gerenu, G; Gil-Bea, FJ; Ramírez, MJ; Solas, M, 2013)
" We found that chronic administration of 11-DHC to male C57BL/6J mice resulted in increased circulating glucocorticoids, and down-regulation of the hypothalamic-pituitary-adrenal axis."5.3911-Dehydrocorticosterone causes metabolic syndrome, which is prevented when 11β-HSD1 is knocked out in livers of male mice. ( Andersén, H; Bohlooly-Y, M; Cottrell, EC; DeSchoolmeester, J; Harno, E; Keevil, BG; Leighton, B; Turnbull, AV; White, A, 2013)
"We showed that in rats chronically treated with corticosterone, lithium treatment markedly reduced insulin resistance."4.31Lithium treatment mitigates the diabetogenic effects of chronic cortico-therapy. ( Bailbé, D; Delangre, E; Movassat, J; Pommier, G; Tolu, S; Uzan, B, 2023)
"CR induces lipid insufficiency and stress, resulting in global physiological insulin resistance except muscle and enhances glycogen metabolism, culminating in the stability of blood glucose manifests in increased FBG, which compensates for insufficient blood ketones."4.12Calorie Restriction Enhanced Glycogen Metabolism to Compensate for Lipid Insufficiency. ( Gu, Y; Hu, L; Wei, L; Xia, X; Yin, J; Zong, Y, 2022)
" As such, we have studied the impact of HII exposure on glucose tolerance, insulin sensitivity, pancreatic islet morphology, muscle GLUT4 and plasma insulin and corticosterone levels."4.02High-intensity infrasound effects on glucose metabolism in rats. ( Águas, A; Borrecho, G; Brito, J; de Carvalho, AO; Freitas, D; Oliveira, MJ; Oliveira, P; Pereira, GM; Pereira, SS; Santos, M; Tortosa, F, 2021)
" However, in VAT, GCs induce DNL, higher palmitic acid (PA), macrophage infiltration, and proinflammatory cytokine levels, accompanied by systemic nonesterified fatty acid (NEFA) elevation, hyperinsulinemia, and higher homeostatic model assessment for insulin resistance (HOMA-IR) levels compared with diet-induced obesity."3.96Long-term hypercortisolism induces lipogenesis promoting palmitic acid accumulation and inflammation in visceral adipose tissue compared with HFD-induced obesity. ( García-Eguren, G; Giró, O; Hanzu, FA; Sala-Vila, A; Vega-Beyhart, A, 2020)
" Here we reported that long-term corticosterone (CORT) exposure in mice induced weight gain, dyslipidemia as well as hyperglycaemia and systemic insulin resistance."3.91Glucocorticoid-induced insulin resistance is related to macrophage visceral adipose tissue infiltration. ( Bruno, F; Do, TTH; Guillaume, D; Héloïse, D; Marie, G; Marion, B; Marthe, M, 2019)
"Chronic corticosterone treatment led to insulin resistance, fasting hyperinsulinaemia, increased adiposity and dyslipidaemia in male, but not female mice."3.91Androgens sensitise mice to glucocorticoid-induced insulin resistance and fat accumulation. ( Cavanagh, LL; Gasparini, SJ; Henneicke, H; Kim, S; Seibel, MJ; Swarbrick, MM; Thai, LJ; Tu, J; Weber, MC; Zhou, H, 2019)
"We aimed to evaluate the effects of a single (acute) and repeated (chronic) exposure to forced-swimming stressor on glucose tolerance, insulin sensitivity, lipid profile and glycogen content in male rats."3.88Glucometabolic effects of single and repeated exposure to forced-swimming stressor in Sprague-Dawley rats. ( Iranloye, BO; Morakinyo, AO; Ogunsola, OA, 2018)
" Ursolic acid, metformin, gliclazide and their combinations when administered daily for 30 days significantly improved insulin sensitivity apart from behavioral and biochemical alterations in stressed mice."3.88Synergistic action of ursolic acid and metformin in experimental model of insulin resistance and related behavioral alterations. ( Ahuja, S; Akhtar, A; Kumar, A; Mourya, A; Sah, SP, 2018)
"We hypothesized that nicotine would ameliorate insulin resistance (IR) that is accompanied by decreased cardiac glycogen synthase kinase-3 (GSK-3) and plasminogen activator inhibitor-1 (PAI-1)."3.88Ameliorative effect of nicotine exposure on insulin resistance is accompanied by decreased cardiac glycogen synthase kinase-3 and plasminogen activator inhibitor-1 during oral oestrogen-progestin therapy. ( Michael, OS; Olatunji, LA, 2018)
"COC treatment or nicotine exposure led to increased insulin resistance (IR), hemorheological (blood viscosity, hematocrit and plasma viscosity), prothrombotic (plasminogen activator inhibitor-1), pro-inflammatory (uric acid, C-reactive protein, neutrophil/lymphocyte and platelet/lymphocyte ratios) biomarkers and corticosterone."3.85Anti-inflammatory and antithrombotic effects of nicotine exposure in oral contraceptive-induced insulin resistance are glucocorticoid-independent. ( Adeyanju, OA; Areola, ED; Michael, OS; Olatunji, LA; Soladoye, AO, 2017)
"These results demonstrates that hypertension and insulin resistance induced by COC is associated with increased cardiac RAS and PAI-1 gene expression, which is likely to be through corticosterone-dependent but not aldosterone-dependent mechanism."3.85Activation of cardiac renin-angiotensin system and plasminogen activator inhibitor-1 gene expressions in oral contraceptive-induced cardiometabolic disorder. ( Kim, IK; Olatunji, LA; Seok, YM; Usman, TO, 2017)
" The current study compares two methods of corticosterone (CS) delivery in regards to their ability to induce typical adverse outcomes such as fat accrual, insulin resistance, sarcopenia and bone loss."3.83Continuous corticosterone delivery via the drinking water or pellet implantation: A comparative study in mice. ( Gasparini, SJ; Henneicke, H; Kim, S; Seibel, MJ; Weber, MC; Zhou, H, 2016)
" Herein, we have described a mouse model of a depression-like and insulin-resistant (DIR) state induced by the co-treatment of high-fat diet (HFD) and corticosterone (CORT)."3.80Depression-like behaviors in mice subjected to co-treatment of high-fat diet and corticosterone are ameliorated by AICAR and exercise. ( Ji, L; Li, H; Liu, W; Zhai, X, 2014)
"Corticosterone (CORT) and other glucocorticoids cause peripheral insulin resistance and compensatory increases in β-cell mass."3.79Exogenous glucocorticoids and a high-fat diet cause severe hyperglycemia and hyperinsulinemia and limit islet glucose responsiveness in young male Sprague-Dawley rats. ( Beaudry, JL; D'souza, AM; Riddell, MC; Teich, T; Tsushima, R, 2013)
" Osteoblast-targeted disruption of glucocorticoid signaling significantly attenuated the suppression of osteocalcin synthesis and prevented the development of insulin resistance, glucose intolerance, and abnormal weight gain in corticosterone-treated mice."3.78Osteoblasts mediate the adverse effects of glucocorticoids on fuel metabolism. ( Blankenstein, KI; Brennan-Speranza, TC; Buttgereit, F; Cogger, VC; Cooney, GJ; Dunstan, CR; Gasparini, SJ; Gundberg, C; Heinevetter, U; Henneicke, H; Seibel, MJ; Svistounov, D; Zhang, Y; Zhou, H, 2012)
"Our findings suggest that HF consumption can lead to the elevation of corticosterone and peripheral insulin resistance, which could contribute to neuronal insulin resistance and neuronal stress."3.77Effects of high-fat diet on insulin receptor function in rat hippocampus and the level of neuronal corticosterone. ( Chattipakorn, N; Chattipakorn, SC; Kerdphoo, S; Petsophonsakul, P; Pongchaidecha, A; Pratchayasakul, W, 2011)
" When the animals reached adulthood, the groups were subdivided and the rats were submitted or not to CVS, which consisted of daily exposure to different stressors for 40 days, followed by a period of behavioral tasks, biochemical (plasma corticosterone and insulin sensitivity) and neurochemical (Na⁺,K⁺-ATPase activity in hippocampus, amygdala and parietal cortex) measurements."3.77Association between Na⁺,K⁺-ATPase activity and the vulnerability/resilience to mood disorders induced by early life experience. ( Benetti, Cda S; Dalmaz, C; Lucion, AB; Mattos, CB; Portella, AK; Scherer, EB; Silveira, PP; Wyse, AT; Zugno, AI, 2011)
" With age, they developed obesity, hyperleptinaemia, hyperinsulinaemia and hyperglycaemia."3.76Pregnancy and lactation have anti-obesity and anti-diabetic effects in A(y)/a mice. ( Bazhan, NM; Makarova, EN; Shevchenko, AY; Yakovleva, TV, 2010)
" We examined whether treatment with a selective serotonin reuptake inhibitor [escitalopram (ESC)] could downregulate HPA axis activity and restore insulin sensitivity in LBW rats."3.76Treatment with an SSRI antidepressant restores hippocampo-hypothalamic corticosteroid feedback and reverses insulin resistance in low-birth-weight rats. ( Buhl, CS; Buhl, ES; Elfving, B; Jensen, TK; Jessen, N; Kristiansen, SB; Lund, S; Petersen, KF; Pold, R; Schmitz, O; Solskov, L; Wegener, G, 2010)
"The intake of a high-fat diet by rats induced a significant increase in body weight, adiposity and insulin resistance markers as well as a decrease in faecal corticosterone levels compared with standard diet-fed rats."3.75Ascorbic acid oral treatment modifies lipolytic response and behavioural activity but not glucocorticoid metabolism in cafeteria diet-fed rats. ( Campion, J; Garcia-Diaz, DF; Martinez, JA; Milagro, FI; Paternain, L; Solomon, A, 2009)
"Our objectives in this study were (1) to estimate sympathetic-adrenal medullary (SAM) activity by measuring mean systolic blood pressure (MSAP) in rats with estradiol valerate (EV)-induced PCO; (2) to estimate alpha1a and alpha2a adrenoceptor expression in a brain area thought to mediate central effects on MSAP regulation and in the adrenal medulla; (3) to assess hypothalamic-pituitary-adrenal (HPA) axis regulation by measuring adrenocorticotropic hormone (ACTH) and corticosterone (CORT) levels in response to novel-environment stress; and (4) to measure abdominal obesity, sex steroids, and insulin sensitivity."3.73Rats with steroid-induced polycystic ovaries develop hypertension and increased sympathetic nervous system activity. ( Holmäng, A; Larsson, BM; Ploj, K; Stener-Victorin, E, 2005)
"MSG rats developed increased adrenocortical function, hyperadiposity, hyperleptinemia, hyperinsulinemia and decreased peripheral insulin sensitivity."3.73Impact of transient correction of increased adrenocortical activity in hypothalamo-damaged, hyperadipose female rats. ( Camihort, G; Console, G; Gaillard, RC; Luna, G; Moreno, G; Perelló, M; Spinedi, E, 2006)
" The first experiment was conducted to determine the effects of lipoic acid (ALA; 200 mg/kg) on plasma lipids and insulin sensitivity of whole-body tissue in broilers treated with or without corticosterone (5 mg/kg)."3.73Effects of dietary lipoic acid on plasma lipid, in vivo insulin sensitivity, metabolic response to corticosterone and in vitro lipolysis in broiler chickens. ( Hamano, Y, 2006)
" To investigate the possible mechanisms of antipsychotic-induced metabolic effects, we studied the impact of chronic administration of a typical antipsychotic drug (haloperidol) and an atypical antipsychotic (risperidone) to male rats on food intake, body weight, adiposity, and the circulating concentrations of hormones and metabolites that can influence energy homeostasis."3.73Distinct endocrine effects of chronic haloperidol or risperidone administration in male rats. ( Dedova, I; Duffy, L; Herzog, H; Karl, T; Lee, NJ; Lin, EJ; Matsumoto, I; O'brien, E; Sainsbury, A; Slack, K, 2006)
"The mechanism by which glucocorticoids induce insulin resistance was studied in normal rats administered for 2 days with corticosterone then tested by euglycaemic hyperinsulinaemic clamps."3.68Involvement of non-esterified fatty acid oxidation in glucocorticoid-induced peripheral insulin resistance in vivo in rats. ( Assimacopoulos-Jeannet, F; Guillaume-Gentil, C; Jeanrenaud, B, 1993)
"2."2.73Corticosterone administration and high-energy feed results in enhanced fat accumulation and insulin resistance in broiler chickens. ( Jiang, KJ; Jiao, HC; Lin, H; Song, ZG; Yuan, L, 2008)
"Mycophenolic acid was detected in all cats."2.61 ( Abrams, G; Adolfsson, E; Agarwal, PK; Akkan, AG; Al Alhareth, NS; Alves, VGL; Armentano, R; Bahroos, E; Baig, M; Baldridge, KK; Barman, S; Bartolucci, C; Basit, A; Bertoli, SV; Bian, L; Bigatti, G; Bobenko, AI; Boix, PP; Bokulic, T; Bolink, HJ; Borowiec, J; Bulski, W; Burciaga, J; Butt, NS; Cai, AL; Campos, AM; Cao, G; Cao, Y; Čapo, I; Caruso, ML; Chao, CT; Cheatum, CM; Chelminski, K; Chen, AJW; Chen, C; Chen, CH; Chen, D; Chen, G; Chen, H; Chen, LH; Chen, R; Chen, RX; Chen, X; Cherdtrakulkiat, R; Chirvony, VS; Cho, JG; Chu, K; Ciurlino, D; Coletta, S; Contaldo, G; Crispi, F; Cui, JF; D'Esposito, M; de Biase, S; Demir, B; Deng, W; Deng, Z; Di Pinto, F; Domenech-Ximenos, B; Dong, G; Drácz, L; Du, XJ; Duan, LJ; Duan, Y; Ekendahl, D; Fan, W; Fang, L; Feng, C; Followill, DS; Foreman, SC; Fortunato, G; Frew, R; Fu, M; Gaál, V; Ganzevoort, W; Gao, DM; Gao, X; Gao, ZW; Garcia-Alvarez, A; Garza, MS; Gauthier, L; Gazzaz, ZJ; Ge, RS; Geng, Y; Genovesi, S; Geoffroy, V; Georg, D; Gigli, GL; Gong, J; Gong, Q; Groeneveld, J; Guerra, V; Guo, Q; Guo, X; Güttinger, R; Guyo, U; Haldar, J; Han, DS; Han, S; Hao, W; Hayman, A; He, D; Heidari, A; Heller, S; Ho, CT; Ho, SL; Hong, SN; Hou, YJ; Hu, D; Hu, X; Hu, ZY; Huang, JW; Huang, KC; Huang, Q; Huang, T; Hwang, JK; Izewska, J; Jablonski, CL; Jameel, T; Jeong, HK; Ji, J; Jia, Z; Jiang, W; Jiang, Y; Kalumpha, M; Kang, JH; Kazantsev, P; Kazemier, BM; Kebede, B; Khan, SA; Kiss, J; Kohen, A; Kolbenheyer, E; Konai, MM; Koniarova, I; Kornblith, E; Krawetz, RJ; Kreouzis, T; Kry, SF; Laepple, T; Lalošević, D; Lan, Y; Lawung, R; Lechner, W; Lee, KH; Lee, YH; Leonard, C; Li, C; Li, CF; Li, CM; Li, F; Li, J; Li, L; Li, S; Li, X; Li, Y; Li, YB; Li, Z; Liang, C; Lin, J; Lin, XH; Ling, M; Link, TM; Liu, HH; Liu, J; Liu, M; Liu, W; Liu, YP; Lou, H; Lu, G; Lu, M; Lun, SM; Ma, Z; Mackensen, A; Majumdar, S; Martineau, C; Martínez-Pastor, JP; McQuaid, JR; Mehrabian, H; Meng, Y; Miao, T; Miljković, D; Mo, J; Mohamed, HSH; Mohtadi, M; Mol, BWJ; Moosavi, L; Mosdósi, B; Nabu, S; Nava, E; Ni, L; Novakovic-Agopian, T; Nyamunda, BC; Nyul, Z; Önal, B; Özen, D; Özyazgan, S; Pajkrt, E; Palazon, F; Park, HW; Patai, Á; Patai, ÁV; Patzke, GR; Payette, G; Pedoia, V; Peelen, MJCS; Pellitteri, G; Peng, J; Perea, RJ; Pérez-Del-Rey, D; Popović, DJ; Popović, JK; Popović, KJ; Posecion, L; Povall, J; Prachayasittikul, S; Prachayasittikul, V; Prat-González, S; Qi, B; Qu, B; Rakshit, S; Ravelli, ACJ; Ren, ZG; Rivera, SM; Salo, P; Samaddar, S; Samper, JLA; Samy El Gendy, NM; Schmitt, N; Sekerbayev, KS; Sepúlveda-Martínez, Á; Sessolo, M; Severi, S; Sha, Y; Shen, FF; Shen, X; Shen, Y; Singh, P; Sinthupoom, N; Siri, S; Sitges, M; Slovak, JE; Solymosi, N; Song, H; Song, J; Song, M; Spingler, B; Stewart, I; Su, BL; Su, JF; Suming, L; Sun, JX; Tantimavanich, S; Tashkandi, JM; Taurbayev, TI; Tedgren, AC; Tenhunen, M; Thwaites, DI; Tibrewala, R; Tomsejm, M; Triana, CA; Vakira, FM; Valdez, M; Valente, M; Valentini, AM; Van de Winckel, A; van der Lee, R; Varga, F; Varga, M; Villarino, NF; Villemur, R; Vinatha, SP; Vincenti, A; Voskamp, BJ; Wang, B; Wang, C; Wang, H; Wang, HT; Wang, J; Wang, M; Wang, N; Wang, NC; Wang, Q; Wang, S; Wang, X; Wang, Y; Wang, Z; Wen, N; Wesolowska, P; Willis, M; Wu, C; Wu, D; Wu, L; Wu, X; Wu, Z; Xia, JM; Xia, X; Xia, Y; Xiao, J; Xiao, Y; Xie, CL; Xie, LM; Xie, S; Xing, Z; Xu, C; Xu, J; Yan, D; Yan, K; Yang, S; Yang, X; Yang, XW; Ye, M; Yin, Z; Yoon, N; Yoon, Y; Yu, H; Yu, K; Yu, ZY; Zhang, B; Zhang, GY; Zhang, H; Zhang, J; Zhang, M; Zhang, Q; Zhang, S; Zhang, W; Zhang, X; Zhang, Y; Zhang, YW; Zhang, Z; Zhao, D; Zhao, F; Zhao, P; Zhao, W; Zhao, Z; Zheng, C; Zhi, D; Zhou, C; Zhou, FY; Zhu, D; Zhu, J; Zhu, Q; Zinyama, NP; Zou, M; Zou, Z, 2019)
"Losartan treatment alleviated some of the T2DM- induced metabolic complications, abolished the T2DM-induced hypo activity, and normalized the corticosterone level, carbonylated proteins in brain, nociception and memory."1.56Protective effects of losartan on some type 2 diabetes mellitus-induced complications in Wistar and spontaneously hypertensive rats. ( Grozdanov, P; Kostadinova, N; Krumova, E; Mitreva-Staleva, J; Pechlivanova, D; Stoynev, A, 2020)
"Stress adaptation disorder exists in gestational diabetes mellitus (GDM) women, this study was to investigate the impact of stress adaptation disorder on glucose disposal and skeletal muscle glucose transporter4 (GLUT4) expression in GDM rat model."1.56Stress adaptation disorders play a role in rat gestational diabetes with oxidative stress and glucose transporter-4 expression. ( Feng, Q; Feng, Y; Hu, J; Qu, H; Song, X; Xu, X; Yin, S, 2020)
"Corticosterone treatment increased adipose tissue mass in both sexes, which was reflected by elevated serum leptin levels."1.51Sex Difference in Corticosterone-Induced Insulin Resistance in Mice. ( Grefhorst, A; Kaikaew, K; Steenbergen, J; van Dijk, TH; Visser, JA, 2019)
"EGCG alone and particularly in combination with exendin-4 exerts positive metabolic properties in HF mice."1.48Beneficial metabolic effects of dietary epigallocatechin gallate alone and in combination with exendin-4 in high fat diabetic mice. ( Flatt, PR; Gault, VA; Millar, PJB; Pathak, NM; Pathak, V, 2018)
"Excessive glucocorticoid (GC) in type 2 diabetes mellitus (T2DM) reduces insulin sensitivity, impairs β-cell function, increases gluconeogenesis and glycogenolysis, impairs glucose uptake and metabolism, and reduces the insulinotropic effects of glucagon-like peptide 1."1.46Neu-P11, a novel MT1/MT2 agonist, reverses diabetes by suppressing the hypothalamic-pituitary-adrenal axis in rats. ( Jia, Z; Laudon, M; Li, M; Luo, X; Yue, Y; Zhang, J; Zhang, R; Zhou, J, 2017)
"Insulin resistance has been identified as the key mechanism linking depression and diabetes."1.46Curcumin reverses the depressive-like behavior and insulin resistance induced by chronic mild stress. ( Li, YC; Li, YJ; Qiao, JY; Shen, JD; Wei, Y, 2017)
"Chronic stress or long-term administration of glucocorticoids disrupts the hypothalamus-pituitary-adrenal system leading to continuous high levels of glucocorticoids and insulin resistance (IR)."1.40Long-term corticosterone exposure decreases insulin sensitivity and induces depressive-like behaviour in the C57BL/6NCrl mouse. ( Blokland, A; Cañete, R; Pawluski, JL; Sierksma, AS; Steinbusch, HW; Vaessen, KR; van Donkelaar, EL, 2014)
" We found that chronic administration of 11-DHC to male C57BL/6J mice resulted in increased circulating glucocorticoids, and down-regulation of the hypothalamic-pituitary-adrenal axis."1.3911-Dehydrocorticosterone causes metabolic syndrome, which is prevented when 11β-HSD1 is knocked out in livers of male mice. ( Andersén, H; Bohlooly-Y, M; Cottrell, EC; DeSchoolmeester, J; Harno, E; Keevil, BG; Leighton, B; Turnbull, AV; White, A, 2013)
"Corticosterone treatment induced an increased expression of stress-activated c-Jun N-terminal kinase (JNK) in the hippocampus, accompanied by decreases in glycogen synthase kinase 3β, increases in pTau levels and increased neuronal cell death (caspase-3 activity)."1.39Mineralocorticoid receptor activation induces insulin resistance through c-Jun N-terminal kinases in response to chronic corticosterone: cognitive implications. ( Gerenu, G; Gil-Bea, FJ; Ramírez, MJ; Solas, M, 2013)
"Propranolol is a β-adrenergic antagonist commonly used in the treatment of hypertension or acute anxiety."1.39Propranolol reduces cognitive deficits, amyloid β levels, tau phosphorylation and insulin resistance in response to chronic corticosterone administration. ( Aguirre, N; Dobarro, M; Orejana, L; Ramírez, MJ, 2013)
"Male obesity is associated with reduced sperm motility and morphology and increased sperm DNA damage and oxidative stress; however, the reversibility of these phenotypes has never been studied."1.38Diet and exercise in an obese mouse fed a high-fat diet improve metabolic health and reverse perturbed sperm function. ( Bakos, HW; Lane, M; Owens, JA; Palmer, NO; Setchell, BP, 2012)
"Poor fetal growth, also known as intrauterine growth restriction (IUGR), is a worldwide health concern."1.38Early metabolic defects in dexamethasone-exposed and undernourished intrauterine growth restricted rats. ( Aubert, ML; Cettour-Rose, P; Guérardel, A; Hüppi, PS; Klee, P; Meda, P; Schwitzgebel, VM; Somm, E; Toulotte, A; Vauthay, DM, 2012)
"Chromium is an important modulator in insulin and glucose metabolism."1.37Is chromium from stainless steel utensils responsible for epidemic of type 2 diabetes? ( Gambhir, PS; Phadke, MA, 2011)
"We investigated whether long-term administration of exogenous corticosterone (CST) or vehicle as daily treatment induces changes in rat behavior and in gene expression of the rat brain insulin signaling pathway and the formation of tau protein."1.36Chronic exogenous corticosterone administration generates an insulin-resistant brain state in rats. ( Grünblatt, E; Hoyer, S; Osmanovic, J; Plaschke, K; Riederer, P; Salkovic-Petrisic, M, 2010)
"Corticosterone pellets were implanted subcutaneously in rats (hypercorticosteronemia, Hypercort) for 2 wk."1.36Effects of excess corticosterone on LKB1 and AMPK signaling in rat skeletal muscle. ( Fillmore, N; Jacobs, DL; Nakken, GN; Thomson, DM; Winder, WW, 2010)
"We performed surgical trauma in male rats of three different ages (3-, 6-, and 10-weeks old)."1.35Age and tissue specific differences in the development of acute insulin resistance following injury. ( Messina, JL; Zhai, L, 2009)
"These results suggest that in type 2 diabetes, blood glucose derangement due to stress is presumably associated not only with changes in counterregulatory hormones involved in glucose metabolism, but also with stress-induced changes in eating behavior."1.31Environmental stress modifies glycemic control and diabetes onset in type 2 diabetes prone Otsuka Long Evans Tokushima Fatty (OLETF) rats. ( Eto, S; Kai, K; Kanda, K; Morimoto, I; Morita, E; Okada, Y; Uriu, K; Yamamoto, S, 2000)
"Insulin sensitivity was assessed by means of an intravenous glucose tolerance test (IVGTT)."1.31Excess portal venous long-chain fatty acids induce syndrome X via HPA axis and sympathetic activation. ( Benthem, L; Keizer, K; Kuipers, F; Scheurink, AJ; Steffens, AB; Strubbe, JH; Wiegman, CH, 2000)
"The T-treated rats showed insulin resistance with both techniques, which was overcome with time and increasing insulin concentrations during the clamp measurements."1.30Imprinting of female offspring with testosterone results in insulin resistance and changes in body fat distribution at adult age in rats. ( Björntorp, P; Eriksson, E; Holmäng, A; Niklasson, M; Nilsson, C, 1998)
"Dexfenfluramine has been shown to lower blood glucose concentrations independently of its effects in reducing food intake and body weight, in human and animal syndromes of non-insulin dependent diabetes."1.29Acute dexfenfluramine administration normalizes glucose tolerance in rats with insulin-deficient diabetes. ( Arora, R; Dryden, S; McKibbin, PE; Williams, G, 1994)
"Glycogen synthesis was followed similarly with [U-14C]glucose as a labelled precursor after isolation of glycogen in the muscles mentioned, and in the liver."1.28The effects of testosterone on insulin sensitivity in male rats. ( Björntorp, P; Holmäng, A, 1992)
"Whereas obesity was associated with only moderate glucose intolerance and insulin resistance in A/J mice, obese C57BL/6J mice showed clear-cut diabetes with fasting blood glucose levels of greater than 240 mg/dl and blood insulin levels of greater than 150 microU/ml."1.27Diet-induced type II diabetes in C57BL/6J mice. ( Cochrane, C; Feinglos, MN; Kuhn, CM; McCubbin, JA; Surwit, RS, 1988)
"Insulin resistance was restored by giving corticosterone together with trilostane."1.26Evidence for a role of glucocorticoids in the development of insulin resistance after ischaemic limb injury in the rat. ( Barton, RN; Passingham, BJ, 1980)

Research

Studies (131)

TimeframeStudies, this research(%)All Research%
pre-19903 (2.29)18.7374
1990's9 (6.87)18.2507
2000's38 (29.01)29.6817
2010's68 (51.91)24.3611
2020's13 (9.92)2.80

Authors

AuthorsStudies
Hu, L1
Xia, X2
Zong, Y1
Gu, Y1
Wei, L1
Yin, J1
Antevska, A3
Long, CC3
Dupuy, SD3
Collier, JJ6
Karlstad, MD5
Do, TD3
Delangre, E1
Pommier, G1
Tolu, S1
Uzan, B1
Bailbé, D1
Movassat, J1
Linden, MA1
Burke, SJ3
Pirzadah, HA1
Huang, TY2
Batdorf, HM3
Mohammed, WK1
Jones, KA2
Ghosh, S1
Campagna, SR2
Noland, RC3
Harvey, I1
Richard, AJ1
Mendoza, TM1
Stephens, JM1
Xu, J2
Shao, X1
Zeng, H1
Wang, C2
Li, J7
Peng, X1
Zhuo, Y1
Hua, L1
Meng, F1
Han, X1
Bobenko, AI1
Heller, S1
Schmitt, N1
Cherdtrakulkiat, R1
Lawung, R1
Nabu, S1
Tantimavanich, S1
Sinthupoom, N1
Prachayasittikul, S1
Prachayasittikul, V1
Zhang, B1
Wu, C1
Zhang, Z2
Yan, K1
Li, C2
Li, Y5
Li, L4
Zheng, C1
Xiao, Y2
He, D1
Zhao, F1
Su, JF1
Lun, SM1
Hou, YJ1
Duan, LJ1
Wang, NC1
Shen, FF1
Zhang, YW1
Gao, ZW1
Du, XJ1
Zhou, FY1
Yin, Z1
Zhu, J2
Yan, D1
Lou, H1
Yu, H1
Feng, C1
Wang, Z1
Wang, Y9
Hu, X2
Li, Z3
Shen, Y1
Hu, D1
Chen, H1
Wu, X1
Duan, Y1
Zhi, D1
Zou, M2
Zhao, Z1
Zhang, X2
Yang, X2
Zhang, J4
Wang, H2
Popović, KJ1
Popović, DJ1
Miljković, D1
Lalošević, D1
Čapo, I1
Popović, JK1
Liu, M1
Song, H2
Xing, Z1
Lu, G1
Chen, D1
Valentini, AM1
Di Pinto, F1
Coletta, S1
Guerra, V1
Armentano, R1
Caruso, ML1
Gong, J1
Wang, N1
Bian, L1
Wang, M1
Ye, M1
Wen, N1
Fu, M1
Fan, W2
Meng, Y1
Dong, G1
Lin, XH1
Liu, HH1
Gao, DM1
Cui, JF1
Ren, ZG1
Chen, RX1
Önal, B1
Özen, D1
Demir, B1
Akkan, AG1
Özyazgan, S1
Payette, G1
Geoffroy, V1
Martineau, C1
Villemur, R1
Jameel, T1
Baig, M1
Gazzaz, ZJ1
Tashkandi, JM1
Al Alhareth, NS1
Khan, SA1
Butt, NS1
Wang, J4
Geng, Y1
Zhang, Y5
Wang, X2
Liu, J3
Basit, A1
Miao, T1
Liu, W3
Jiang, W1
Yu, ZY1
Wu, L2
Qu, B1
Sun, JX1
Cai, AL1
Xie, LM1
Groeneveld, J1
Ho, SL1
Mackensen, A1
Mohtadi, M1
Laepple, T1
Genovesi, S1
Nava, E1
Bartolucci, C1
Severi, S1
Vincenti, A1
Contaldo, G1
Bigatti, G1
Ciurlino, D1
Bertoli, SV1
Slovak, JE1
Hwang, JK1
Rivera, SM1
Villarino, NF1
Li, S2
Cao, G1
Ling, M1
Ji, J1
Zhao, D1
Sha, Y1
Gao, X1
Liang, C2
Guo, Q1
Zhou, C1
Ma, Z1
Zhao, W2
Jiang, Y1
Peng, J1
Jia, Z2
Li, F1
Chen, X3
Mo, J1
Zhang, S2
Li, X1
Huang, T1
Zhu, Q1
Wang, S1
Ge, RS1
Fortunato, G1
Lin, J2
Agarwal, PK1
Kohen, A1
Singh, P1
Cheatum, CM1
Zhu, D1
Hayman, A1
Kebede, B1
Stewart, I1
Chen, G1
Frew, R1
Guo, X1
Gong, Q1
Borowiec, J1
Han, S1
Zhang, M1
Willis, M1
Kreouzis, T1
Yu, K1
Chirvony, VS1
Sekerbayev, KS1
Pérez-Del-Rey, D1
Martínez-Pastor, JP1
Palazon, F1
Boix, PP1
Taurbayev, TI1
Sessolo, M1
Bolink, HJ1
Lu, M1
Lan, Y1
Xiao, J1
Song, M1
Chen, C1
Huang, Q1
Cao, Y1
Ho, CT1
Qi, B1
Wang, Q1
Zhang, W1
Fang, L1
Xie, CL1
Chen, R1
Yang, S1
Xia, JM1
Zhang, GY1
Chen, CH1
Yang, XW1
Domenech-Ximenos, B1
Garza, MS1
Prat-González, S1
Sepúlveda-Martínez, Á1
Crispi, F1
Perea, RJ1
Garcia-Alvarez, A1
Sitges, M1
Kalumpha, M1
Guyo, U1
Zinyama, NP1
Vakira, FM1
Nyamunda, BC1
Varga, M1
Drácz, L1
Kolbenheyer, E1
Varga, F1
Patai, ÁV1
Solymosi, N1
Patai, Á1
Kiss, J1
Gaál, V1
Nyul, Z1
Mosdósi, B1
Valdez, M1
Moosavi, L1
Heidari, A1
Novakovic-Agopian, T1
Kornblith, E1
Abrams, G1
McQuaid, JR1
Posecion, L1
Burciaga, J1
D'Esposito, M1
Chen, AJW1
Samy El Gendy, NM1
Wesolowska, P1
Georg, D1
Lechner, W1
Kazantsev, P1
Bokulic, T1
Tedgren, AC1
Adolfsson, E1
Campos, AM1
Alves, VGL1
Suming, L1
Hao, W1
Ekendahl, D1
Koniarova, I1
Bulski, W1
Chelminski, K1
Samper, JLA1
Vinatha, SP1
Rakshit, S1
Siri, S1
Tomsejm, M1
Tenhunen, M1
Povall, J1
Kry, SF1
Followill, DS1
Thwaites, DI1
Izewska, J1
Kang, JH1
Yoon, Y1
Song, J1
Van de Winckel, A1
Gauthier, L1
Chao, CT1
Lee, YH1
Li, CM1
Han, DS1
Huang, JW1
Huang, KC1
Ni, L1
Güttinger, R1
Triana, CA1
Spingler, B1
Baldridge, KK1
Patzke, GR1
Shen, X1
Wang, B1
Xie, S1
Deng, W1
Wu, D1
Zhang, Q1
Voskamp, BJ1
Peelen, MJCS1
Ravelli, ACJ1
van der Lee, R1
Mol, BWJ1
Pajkrt, E1
Ganzevoort, W1
Kazemier, BM1
Tibrewala, R1
Bahroos, E1
Mehrabian, H1
Foreman, SC1
Link, TM1
Pedoia, V1
Majumdar, S1
Jablonski, CL1
Leonard, C1
Salo, P1
Krawetz, RJ1
Yoon, N1
Hong, SN1
Cho, JG1
Jeong, HK1
Lee, KH1
Park, HW1
Barman, S1
Konai, MM1
Samaddar, S1
Haldar, J1
Mohamed, HSH1
Li, CF1
Hu, ZY1
Deng, Z1
Chen, LH1
Su, BL1
Chu, K1
Liu, YP1
Li, YB1
Zhang, H1
Xu, C1
Zou, Z1
Wu, Z1
Xia, Y1
Zhao, P1
Wang, HT1
de Biase, S1
Pellitteri, G1
Gigli, GL1
Valente, M1
Uehara, M1
Yamazaki, H1
Yoshikawa, N1
Kuribara-Souta, A1
Tanaka, H1
Jackson, JW1
Martin, TM1
Rohli, KE1
Sparer, TE1
Burk, DH2
Soto, PL1
Liu, L3
Lutfy, K3
Friedman, TC3
Liu, Y5
Jiang, M2
Patterson, E1
Ryan, PM1
Wiley, N1
Carafa, I1
Sherwin, E1
Moloney, G1
Franciosi, E1
Mandal, R1
Wishart, DS1
Tuohy, K1
Ross, RP1
Cryan, JF1
Dinan, TG1
Stanton, C1
Sadeghimahalli, F1
Zardooz, H2
Golchoobian, R1
Feng, Y1
Feng, Q1
Yin, S1
Xu, X1
Song, X1
Qu, H1
Hu, J1
Pechlivanova, D1
Krumova, E1
Kostadinova, N1
Mitreva-Staleva, J1
Grozdanov, P1
Stoynev, A1
García-Eguren, G2
Sala-Vila, A1
Giró, O2
Vega-Beyhart, A1
Hanzu, FA2
Cai, J1
Lin, Y1
Xiao, X1
Guo, J1
Hendrickx, JO1
De Moudt, S1
Calus, E1
Martinet, W1
Guns, PDF1
Roth, L1
De Deyn, PP1
Van Dam, D1
De Meyer, GRY1
Pereira, GM1
Santos, M1
Pereira, SS1
Borrecho, G1
Tortosa, F1
Brito, J1
Freitas, D1
de Carvalho, AO1
Águas, A1
Oliveira, MJ1
Oliveira, P1
Olatunji, LA3
Michael, OS2
Adeyanju, OA1
Areola, ED1
Soladoye, AO1
Shen, JD1
Wei, Y1
Li, YJ1
Qiao, JY1
Li, YC1
Zhou, J1
Luo, X1
Li, M1
Yue, Y1
Laudon, M1
Zhang, R1
Pathak, NM1
Millar, PJB1
Pathak, V1
Flatt, PR4
Gault, VA4
Rijnsburger, M1
Eggels, L1
Castel, J1
Cruciani-Guglielmacci, C1
Ackermans, MT1
Luquet, S1
la Fleur, SE1
Teich, T3
Pivovarov, JA1
Porras, DP1
Dunford, EC2
Riddell, MC5
Mantor, D1
Pratchayasakul, W2
Minta, W1
Sutham, W1
Palee, S1
Sripetchwandee, J1
Kerdphoo, S2
Jaiwongkum, T1
Sriwichaiin, S1
Krintratun, W1
Chattipakorn, N2
Chattipakorn, SC2
Morakinyo, AO1
Iranloye, BO1
Ogunsola, OA1
Canini, F1
Qin, B1
Arvy, N1
Poulet, L1
Batandier, C1
Roussel, AM2
Anderson, RA1
Mourya, A2
Akhtar, A1
Ahuja, S2
Sah, SP2
Kumar, A2
Do, TTH1
Marie, G1
Héloïse, D1
Guillaume, D1
Marthe, M1
Bruno, F1
Marion, B1
Gligorovska, L1
Bursać, B1
Kovačević, S1
Veličković, N1
Matić, G1
Djordjevic, A1
Gasparini, SJ3
Swarbrick, MM1
Kim, S2
Thai, LJ1
Henneicke, H3
Cavanagh, LL1
Tu, J1
Weber, MC2
Zhou, H3
Seibel, MJ3
Romero, MDM1
Grasa, M1
Shi, J1
Hao, J1
Pang, X1
Huang, X1
Jin, R1
Ge, Q1
Kaikaew, K1
Steenbergen, J1
van Dijk, TH1
Grefhorst, A1
Visser, JA1
Tsuneki, H1
Tokai, E1
Sugawara, C1
Wada, T1
Sakurai, T1
Sasaoka, T1
Ribeiro, MJ1
Sacramento, JF1
Gonzalez, C1
Guarino, MP1
Monteiro, EC1
Conde, SV1
Beaudry, JL4
D'souza, AM2
Tsushima, R1
Harno, E1
Cottrell, EC1
Keevil, BG1
DeSchoolmeester, J1
Bohlooly-Y, M1
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Kimura, M1
Muto, N1
Yasuda, K1
Jennische, E1
York, DA1
Masuzaki, H1
Paterson, J1
Shinyama, H1
Mullins, JJ1
Flier, JS1
Kibenge, MT1
Chan, CB1
Rao, RH1
Koopmans, SJ1
van Mansfeld, AD1
Jansz, HS1
Krans, HM1
Radder, JK1
Frölich, M1
de Boer, SF1
Kreutter, DK1
Andrews, GC1
Maassen, JA1
Surwit, RS1
Kuhn, CM1
Cochrane, C1
McCubbin, JA1
Feinglos, MN1
Goldfine, ID1
Kahn, CR1
Neville, DM1
Roth, J1
Garrison, MM1
Bates, RW1

Reviews

1 review available for corticosterone and Insulin Resistance

ArticleYear
    Proceedings. Mathematical, physical, and engineering sciences, 2019, Volume: 475, Issue:2227

    Topics: Acetylcholine; Acinetobacter baumannii; Actinobacteria; Action Potentials; Adalimumab; Adaptation, P

2019

Trials

1 trial available for corticosterone and Insulin Resistance

ArticleYear
Corticosterone administration and high-energy feed results in enhanced fat accumulation and insulin resistance in broiler chickens.
    British poultry science, 2008, Volume: 49, Issue:4

    Topics: Adipose Tissue; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Blood Glucose; Bod

2008

Other Studies

129 other studies available for corticosterone and Insulin Resistance

ArticleYear
Calorie Restriction Enhanced Glycogen Metabolism to Compensate for Lipid Insufficiency.
    Molecular nutrition & food research, 2022, Volume: 66, Issue:20

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Caloric Restriction; Corticosterone; Fatty Acids, Non

2022
Mouse Pancreatic Peptide Hormones Probed at the Sub-Single-Islet Level: The Effects of Acute Corticosterone Treatment.
    Journal of proteome research, 2023, 01-06, Volume: 22, Issue:1

    Topics: Animals; Corticosterone; Insulin; Insulin Resistance; Insulin-Secreting Cells; Mice

2023
Mouse Pancreatic Peptide Hormones Probed at the Sub-Single-Islet Level: The Effects of Acute Corticosterone Treatment.
    Journal of proteome research, 2023, 01-06, Volume: 22, Issue:1

    Topics: Animals; Corticosterone; Insulin; Insulin Resistance; Insulin-Secreting Cells; Mice

2023
Mouse Pancreatic Peptide Hormones Probed at the Sub-Single-Islet Level: The Effects of Acute Corticosterone Treatment.
    Journal of proteome research, 2023, 01-06, Volume: 22, Issue:1

    Topics: Animals; Corticosterone; Insulin; Insulin Resistance; Insulin-Secreting Cells; Mice

2023
Mouse Pancreatic Peptide Hormones Probed at the Sub-Single-Islet Level: The Effects of Acute Corticosterone Treatment.
    Journal of proteome research, 2023, 01-06, Volume: 22, Issue:1

    Topics: Animals; Corticosterone; Insulin; Insulin Resistance; Insulin-Secreting Cells; Mice

2023
Mouse Pancreatic Peptide Hormones Probed at the Sub-Single-Islet Level: The Effects of Acute Corticosterone Treatment.
    Journal of proteome research, 2023, 01-06, Volume: 22, Issue:1

    Topics: Animals; Corticosterone; Insulin; Insulin Resistance; Insulin-Secreting Cells; Mice

2023
Mouse Pancreatic Peptide Hormones Probed at the Sub-Single-Islet Level: The Effects of Acute Corticosterone Treatment.
    Journal of proteome research, 2023, 01-06, Volume: 22, Issue:1

    Topics: Animals; Corticosterone; Insulin; Insulin Resistance; Insulin-Secreting Cells; Mice

2023
Mouse Pancreatic Peptide Hormones Probed at the Sub-Single-Islet Level: The Effects of Acute Corticosterone Treatment.
    Journal of proteome research, 2023, 01-06, Volume: 22, Issue:1

    Topics: Animals; Corticosterone; Insulin; Insulin Resistance; Insulin-Secreting Cells; Mice

2023
Mouse Pancreatic Peptide Hormones Probed at the Sub-Single-Islet Level: The Effects of Acute Corticosterone Treatment.
    Journal of proteome research, 2023, 01-06, Volume: 22, Issue:1

    Topics: Animals; Corticosterone; Insulin; Insulin Resistance; Insulin-Secreting Cells; Mice

2023
Mouse Pancreatic Peptide Hormones Probed at the Sub-Single-Islet Level: The Effects of Acute Corticosterone Treatment.
    Journal of proteome research, 2023, 01-06, Volume: 22, Issue:1

    Topics: Animals; Corticosterone; Insulin; Insulin Resistance; Insulin-Secreting Cells; Mice

2023
Lithium treatment mitigates the diabetogenic effects of chronic cortico-therapy.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 164

    Topics: Animals; Blood Glucose; Corticosterone; Dexamethasone; Diabetes Mellitus; Glucocorticoids; Gluconeog

2023
Pharmacological inhibition of lipolysis prevents adverse metabolic outcomes during glucocorticoid administration.
    Molecular metabolism, 2023, Volume: 74

    Topics: Animals; Corticosterone; Glucocorticoids; Glucose; Iatrogenic Disease; Insulin Resistance; Lipolysis

2023
Adipocyte STAT5 (signal transducer and activator of transcription 5) is not required for glucocorticoid-induced metabolic dysfunction.
    American journal of physiology. Endocrinology and metabolism, 2023, 11-01, Volume: 325, Issue:5

    Topics: Adipocytes; Animals; Corticosterone; Diabetes Mellitus, Type 2; Female; Glucocorticoids; Insulin Res

2023
Hepatic-Specific FGF21 Knockout Abrogates Ovariectomy-Induced Obesity by Reversing Corticosterone Production.
    International journal of molecular sciences, 2023, Oct-05, Volume: 24, Issue:19

    Topics: Animals; Corticosterone; Diet, High-Fat; Estrogens; Female; Fibroblast Growth Factors; Glucocorticoi

2023
Correlation among body composition and metabolic regulation in a male mouse model of Cushing's syndrome.
    Endocrine journal, 2020, Jan-28, Volume: 67, Issue:1

    Topics: Adipocytes, White; Adipose Tissue; Adipose Tissue, White; Adrenal Cortex Hormones; Alanine; Alanine

2020
One week of continuous corticosterone exposure impairs hepatic metabolic flexibility, promotes islet β-cell proliferation, and reduces physical activity in male C57BL/6 J mice.
    The Journal of steroid biochemistry and molecular biology, 2019, Volume: 195

    Topics: Animals; Body Composition; Cell Proliferation; Corticosterone; Diet, High-Fat; Glucocorticoids; Gluc

2019
Lack of adipose-specific hexose-6-phosphate dehydrogenase causes inactivation of adipose glucocorticoids and improves metabolic phenotype in mice.
    Clinical science (London, England : 1979), 2019, 11-15, Volume: 133, Issue:21

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipose Tissue; Adiposity; Animals; Blood Glucose; Carb

2019
Gamma-aminobutyric acid-producing lactobacilli positively affect metabolism and depressive-like behaviour in a mouse model of metabolic syndrome.
    Scientific reports, 2019, 11-08, Volume: 9, Issue:1

    Topics: Adipose Tissue; Animals; Behavior, Animal; Body Weight; Cholesterol; Corticosterone; Depression; Dis

2019
Early postnatal hypothalamic-pituitary-adrenal axis activity and reduced insulin sensitivity in adult rats.
    Endocrine regulations, 2019, Oct-01, Volume: 53, Issue:4

    Topics: Aging; Animals; Animals, Newborn; Corticosterone; Female; Hypothalamo-Hypophyseal System; Insulin Re

2019
Stress adaptation disorders play a role in rat gestational diabetes with oxidative stress and glucose transporter-4 expression.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2020, Volume: 36, Issue:9

    Topics: Animals; Blood Glucose; Corticosterone; Diabetes, Gestational; Disease Models, Animal; Female; Gener

2020
Protective effects of losartan on some type 2 diabetes mellitus-induced complications in Wistar and spontaneously hypertensive rats.
    Metabolic brain disease, 2020, Volume: 35, Issue:3

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Brain; Corticosterone; Diabetes Mellitus, Experime

2020
Long-term hypercortisolism induces lipogenesis promoting palmitic acid accumulation and inflammation in visceral adipose tissue compared with HFD-induced obesity.
    American journal of physiology. Endocrinology and metabolism, 2020, 06-01, Volume: 318, Issue:6

    Topics: Animals; Corticosterone; Cushing Syndrome; Cytokines; Diet, High-Fat; Fatty Acids; Fatty Acids, None

2020
Comprehensive chemical analysis of Zhenshu Tiaozhi formula and its effect on ameliorating glucolipid metabolic disorders in diabetic rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 133

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adrenocorticotropic Hormone; Animals; Biomarkers; Blood

2021
Serum Corticosterone and Insulin Resistance as Early Biomarkers in the hAPP23 Overexpressing Mouse Model of Alzheimer's Disease.
    International journal of molecular sciences, 2021, Jun-22, Volume: 22, Issue:13

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Biomarkers; Cognitive Dysfunction; Corti

2021
High-intensity infrasound effects on glucose metabolism in rats.
    Scientific reports, 2021, 08-26, Volume: 11, Issue:1

    Topics: Animals; Blood Glucose; Corticosterone; Glucose; Glucose Intolerance; Glucose Transporter Type 4; Im

2021
Anti-inflammatory and antithrombotic effects of nicotine exposure in oral contraceptive-induced insulin resistance are glucocorticoid-independent.
    Pharmacological reports : PR, 2017, Volume: 69, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Blood Viscosity; Contraceptives, Oral; Corticosterone; Dose-Respo

2017
Curcumin reverses the depressive-like behavior and insulin resistance induced by chronic mild stress.
    Metabolic brain disease, 2017, Volume: 32, Issue:4

    Topics: Animals; Behavior, Animal; Blood Glucose; Corticosterone; Curcumin; Depression; Disease Models, Anim

2017
Neu-P11, a novel MT1/MT2 agonist, reverses diabetes by suppressing the hypothalamic-pituitary-adrenal axis in rats.
    European journal of pharmacology, 2017, Oct-05, Volume: 812

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adiponectin; Adipose Tissue; Animals; Blood Glucose; Bo

2017
Beneficial metabolic effects of dietary epigallocatechin gallate alone and in combination with exendin-4 in high fat diabetic mice.
    Molecular and cellular endocrinology, 2018, 01-15, Volume: 460

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adiposity; Alanine Transaminase; Animals; Blood Glucose

2018
A novel, double intra-carotid cannulation technique to study the effect of central nutrient sensing on glucose metabolism in the rat.
    Journal of neuroscience methods, 2017, Oct-01, Volume: 290

    Topics: Analysis of Variance; Animals; Blood Glucose; Carotid Arteries; Catheterization; Corticosterone; Dru

2017
Curcumin limits weight gain, adipose tissue growth, and glucose intolerance following the cessation of exercise and caloric restriction in rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 2017, 12-01, Volume: 123, Issue:6

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipose Tissue; Animals; Caloric Restriction; Corticost

2017
Ameliorative effect of nicotine exposure on insulin resistance is accompanied by decreased cardiac glycogen synthase kinase-3 and plasminogen activator inhibitor-1 during oral oestrogen-progestin therapy.
    Archives of physiology and biochemistry, 2018, Volume: 124, Issue:2

    Topics: Administration, Oral; Aldosterone; Animals; Biomarkers; Cardiovascular Diseases; Contraceptives, Ora

2018
Both oophorectomy and obesity impaired solely hippocampal-dependent memory via increased hippocampal dysfunction.
    Experimental gerontology, 2018, 07-15, Volume: 108

    Topics: Animals; Cognition; Corticosterone; Diet, High-Fat; Estrogens; Female; Hippocampus; Insulin Resistan

2018
Glucometabolic effects of single and repeated exposure to forced-swimming stressor in Sprague-Dawley rats.
    Endocrine regulations, 2018, Apr-01, Volume: 52, Issue:2

    Topics: Animals; Cholesterol; Corticosterone; Glucose; Glycogen; Insulin; Insulin Resistance; Lipoproteins,

2018
Stress exposure alters brain mRNA expression of the genes involved in insulin signalling, an effect modified by a high fat/high fructose diet and cinnamon supplement.
    PloS one, 2018, Volume: 13, Issue:5

    Topics: Animals; Brain; Cinnamomum zeylanicum; Corticosterone; Diet, High-Fat; Diet, Western; Dietary Supple

2018
Synergistic action of ursolic acid and metformin in experimental model of insulin resistance and related behavioral alterations.
    European journal of pharmacology, 2018, Sep-15, Volume: 835

    Topics: Acetylcholinesterase; Adiponectin; Animals; Behavior, Animal; Blood Pressure; Body Weight; Brain; Co

2018
Glucocorticoid-induced insulin resistance is related to macrophage visceral adipose tissue infiltration.
    The Journal of steroid biochemistry and molecular biology, 2019, Volume: 185

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipocytes; Adipose Tissue; Animals; Carbohydrate Dehyd

2019
Mif deficiency promotes adiposity in fructose-fed mice.
    The Journal of endocrinology, 2019, 02-01, Volume: 240, Issue:2

    Topics: Adipocytes; Adipose Tissue; Adiposity; Animals; Corticosterone; Fructose; Gene Expression Regulation

2019
Androgens sensitise mice to glucocorticoid-induced insulin resistance and fat accumulation.
    Diabetologia, 2019, Volume: 62, Issue:8

    Topics: Adipocytes; Adiponectin; Adipose Tissue, Brown; Adiposity; Androgens; Animals; Body Composition; Cor

2019
Chronic hypercortisolism causes more persistent visceral adiposity than HFD-induced obesity.
    The Journal of endocrinology, 2019, Volume: 242, Issue:2

    Topics: Adipose Tissue; Adiposity; Animals; Anti-Inflammatory Agents; Body Weight; Corticosterone; Cushing S

2019
Intestinal microbiota contributes to altered glucose metabolism in simulated microgravity mouse model.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019, Volume: 33, Issue:9

    Topics: Acute-Phase Proteins; Akkermansia; Animals; Bifidobacterium; Carrier Proteins; Corticosterone; Dysbi

2019
Sex Difference in Corticosterone-Induced Insulin Resistance in Mice.
    Endocrinology, 2019, 10-01, Volume: 160, Issue:10

    Topics: Adipokines; Adiponectin; Adipose Tissue; Animals; Blood Glucose; Corticosterone; Female; Gene Expres

2019
Hypothalamic orexin prevents hepatic insulin resistance induced by social defeat stress in mice.
    Neuropeptides, 2013, Volume: 47, Issue:3

    Topics: Animals; Blotting, Western; Corticosterone; Glucose; Glucose Tolerance Test; Homeostasis; Hypothalam

2013
Carotid body denervation prevents the development of insulin resistance and hypertension induced by hypercaloric diets.
    Diabetes, 2013, Volume: 62, Issue:8

    Topics: Animals; Carotid Body; Carotid Sinus; Corticosterone; Denervation; Diet, High-Fat; Fatty Acids, None

2013
Exogenous glucocorticoids and a high-fat diet cause severe hyperglycemia and hyperinsulinemia and limit islet glucose responsiveness in young male Sprague-Dawley rats.
    Endocrinology, 2013, Volume: 154, Issue:9

    Topics: Animals; Circadian Rhythm; Corticosterone; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models

2013
11-Dehydrocorticosterone causes metabolic syndrome, which is prevented when 11β-HSD1 is knocked out in livers of male mice.
    Endocrinology, 2013, Volume: 154, Issue:10

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adiposity; Animals; Biomarkers; Corticosterone; Down-Re

2013
Leptin ameliorates insulin resistance and hepatic steatosis in Agpat2-/- lipodystrophic mice independent of hepatocyte leptin receptors.
    Journal of lipid research, 2014, Volume: 55, Issue:2

    Topics: 1-Acylglycerol-3-Phosphate O-Acyltransferase; Animals; Basic Helix-Loop-Helix Leucine Zipper Transcr

2014
Depression-like behaviors in mice subjected to co-treatment of high-fat diet and corticosterone are ameliorated by AICAR and exercise.
    Journal of affective disorders, 2014, Volume: 156

    Topics: Aminoimidazole Carboxamide; Animals; Corticosterone; Depression; Depressive Disorder; Diet, High-Fat

2014
Elevated hepatic 11β-hydroxysteroid dehydrogenase type 1 induces insulin resistance in uremia.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Mar-11, Volume: 111, Issue:10

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Analysis of Variance; Animals; Blood Glucose; Carbenoxo

2014
Effects of selective and non-selective glucocorticoid receptor II antagonists on rapid-onset diabetes in young rats.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Animals; Blood Glucose; Body Weight; Corticosterone; Diabetes Mellitus, Experimental; Diet, High-Fat

2014
Resveratrol ameliorates mitochondrial dysfunction but increases the risk of hypoglycemia following hemorrhagic shock.
    The journal of trauma and acute care surgery, 2014, Volume: 77, Issue:6

    Topics: Animals; Blood Glucose; Corticosterone; Glucagon; Glucagon-Like Peptide 1; Hypoglycemia; Insulin; In

2014
Long-term corticosterone exposure decreases insulin sensitivity and induces depressive-like behaviour in the C57BL/6NCrl mouse.
    PloS one, 2014, Volume: 9, Issue:10

    Topics: Animals; Behavior, Animal; Blood Glucose; Corticosterone; Depression; Disease Models, Animal; Hypoth

2014
11β-Hydroxysteroid dehydrogenase type 1 shRNA ameliorates glucocorticoid-induced insulin resistance and lipolysis in mouse abdominal adipose tissue.
    American journal of physiology. Endocrinology and metabolism, 2015, Jan-01, Volume: 308, Issue:1

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 3T3-L1 Cells; Abdominal Fat; Adipocytes; Animals; Corti

2015
Correction of Hormonal and Metabolic Disorders in Male Rats with Developing Experimental Diabetes.
    Bulletin of experimental biology and medicine, 2015, Volume: 159, Issue:1

    Topics: Anabolic Agents; Animals; Blood Glucose; Corticosterone; Diabetes Mellitus, Experimental; DNA Replic

2015
The Role of Nitric Oxide in the Antidepressant Actions of 5-Aminoimidazole-4-Carboxamide-1-β-D-Ribofuranoside in Insulin-Resistant Mice.
    Psychosomatic medicine, 2016, Volume: 78, Issue:1

    Topics: Adenylate Kinase; Aminoimidazole Carboxamide; Animals; Antidepressive Agents; Combined Modality Ther

2016
JNK: A Putative Link Between Insulin Signaling and VGLUT1 in Alzheimer's Disease.
    Journal of Alzheimer's disease : JAD, 2016, Volume: 50, Issue:4

    Topics: Aged; Alzheimer Disease; Animals; Brain; Corticosterone; Disease Models, Animal; Female; Humans; Ins

2016
Activation of cardiac renin-angiotensin system and plasminogen activator inhibitor-1 gene expressions in oral contraceptive-induced cardiometabolic disorder.
    Archives of physiology and biochemistry, 2017, Volume: 123, Issue:1

    Topics: Aldosterone; Animals; Ataxia Telangiectasia Mutated Proteins; Cardiovascular Diseases; Contraceptive

2017
The 11β-hydroxysteroid dehydrogenase type 1 inhibitor protects against the insulin resistance and hepatic steatosis in db/db mice.
    European journal of pharmacology, 2016, Oct-05, Volume: 788

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Benzylidene Compounds; Blood Glucose; Body Wei

2016
Metabolic dysfunction in female mice with disruption of 5α-reductase 1.
    The Journal of endocrinology, 2017, Volume: 232, Issue:1

    Topics: Animals; Cholestenone 5 alpha-Reductase; Corticosterone; Diet, High-Fat; Energy Metabolism; Female;

2017
Plausible anti-inflammatory mechanism of resveratrol and caffeic acid against chronic stress-induced insulin resistance in mice.
    Inflammopharmacology, 2016, Volume: 24, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Blood Glucose; Caffeic Acids; Corticosterone; Cytokines; Drug The

2016
Continuous corticosterone delivery via the drinking water or pellet implantation: A comparative study in mice.
    Steroids, 2016, Volume: 116

    Topics: Animals; Corticosterone; Cushing Syndrome; Drinking Water; Drug Implants; Insulin Resistance; Male;

2016
Oral Corticosterone Administration Reduces Insulitis but Promotes Insulin Resistance and Hyperglycemia in Male Nonobese Diabetic Mice.
    The American journal of pathology, 2017, Volume: 187, Issue:3

    Topics: Administration, Oral; Animals; Body Composition; CD3 Complex; Citrate (si)-Synthase; Corticosterone;

2017
ATF4/ATG5 Signaling in Hypothalamic Proopiomelanocortin Neurons Regulates Fat Mass via Affecting Energy Expenditure.
    Diabetes, 2017, Volume: 66, Issue:5

    Topics: Activating Transcription Factor 4; Adipose Tissue; Adipose Tissue, Brown; Adipose Tissue, White; Ani

2017
Reduction of hepatic glucocorticoid receptor and hexose-6-phosphate dehydrogenase expression ameliorates diet-induced obesity and insulin resistance in mice.
    Journal of molecular endocrinology, 2008, Volume: 41, Issue:2

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Blood Glucose; Body Weight; Carbenoxolone; Car

2008
Long-term effects of corticosterone on behavior, oxidative and energy metabolism of parietotemporal cerebral cortex and hippocampus of rats: comparison to intracerebroventricular streptozotocin.
    Journal of neural transmission (Vienna, Austria : 1996), 2008, Volume: 115, Issue:9

    Topics: Adenosine Triphosphate; Animals; Antibiotics, Antineoplastic; Behavior, Animal; Cerebral Cortex; Cit

2008
Effect of sub-deficient zinc status on insulin sensitivity after burn injury in rats.
    Biological trace element research, 2009, Volume: 127, Issue:2

    Topics: Animals; Antioxidants; Blood Glucose; Burns; Corticosterone; Diet; Disease Models, Animal; Femur; In

2009
Tissue-specific difference in the molecular mechanisms for the development of acute insulin resistance after injury.
    Endocrinology, 2009, Volume: 150, Issue:1

    Topics: Acute Disease; Animals; Corticosterone; Fatty Acids, Nonesterified; Hemorrhage; Hormone Antagonists;

2009
Corticosterone suppresses insulin- and NO-stimulated muscle glucose uptake in broiler chickens (Gallus gallus domesticus).
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2009, Volume: 149, Issue:3

    Topics: Animals; Biological Transport; Blood Glucose; Chickens; Corticosterone; Deoxyglucose; Diet; Enzyme I

2009
Ascorbic acid oral treatment modifies lipolytic response and behavioural activity but not glucocorticoid metabolism in cafeteria diet-fed rats.
    Acta physiologica (Oxford, England), 2009, Volume: 195, Issue:4

    Topics: Adipocytes; Adiposity; Administration, Oral; Animals; Antioxidants; Ascorbic Acid; Biomarkers; Body

2009
Plasma adiponectin levels are increased despite insulin resistance in corticotropin-releasing hormone transgenic mice, an animal model of Cushing syndrome.
    Endocrine journal, 2009, Volume: 56, Issue:7

    Topics: Adiponectin; Animals; Corticosterone; Corticotropin-Releasing Hormone; Cushing Syndrome; Disease Mod

2009
Age and tissue specific differences in the development of acute insulin resistance following injury.
    The Journal of endocrinology, 2009, Volume: 203, Issue:3

    Topics: Aging; Animals; Corticosterone; Glucocorticoids; Insulin; Insulin Receptor Substrate Proteins; Insul

2009
Pregnancy and lactation have anti-obesity and anti-diabetic effects in A(y)/a mice.
    Acta physiologica (Oxford, England), 2010, Volume: 198, Issue:2

    Topics: Age Factors; Animals; Blood Glucose; Body Weight; Breast Feeding; Corticosterone; Diabetes Mellitus;

2010
Chronic exogenous corticosterone administration generates an insulin-resistant brain state in rats.
    Stress (Amsterdam, Netherlands), 2010, Volume: 13, Issue:2

    Topics: Animals; Behavior, Animal; Cerebral Cortex; Cognition Disorders; Corticosterone; Gene Expression; In

2010
Effects of excess corticosterone on LKB1 and AMPK signaling in rat skeletal muscle.
    Journal of applied physiology (Bethesda, Md. : 1985), 2010, Volume: 108, Issue:2

    Topics: Adrenal Glands; AMP-Activated Protein Kinase Kinases; Animals; Atrophy; Blotting, Western; Body Weig

2010
Environmental disturbance confounds prenatal glucocorticoid programming experiments in Wistar rats.
    Laboratory animals, 2010, Volume: 44, Issue:3

    Topics: Animals; Animals, Newborn; Birth Weight; Corticosterone; Dexamethasone; Environment; Female; Glucoco

2010
Treatment with an SSRI antidepressant restores hippocampo-hypothalamic corticosteroid feedback and reverses insulin resistance in low-birth-weight rats.
    American journal of physiology. Endocrinology and metabolism, 2010, Volume: 298, Issue:5

    Topics: Adrenocorticotropic Hormone; Analysis of Variance; Animals; Area Under Curve; Blood Glucose; Body We

2010
Glucose homeostasis in pre-diabetic NOD and lymphocyte-deficient NOD/SCID mice during gestation.
    The review of diabetic studies : RDS, 2010,Spring, Volume: 7, Issue:1

    Topics: Animals; Blood Glucose; Corticosterone; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Toleran

2010
Increases in energy intake, insulin resistance and stress in rats before Wenchuan earthquake far from the epicenter.
    Experimental biology and medicine (Maywood, N.J.), 2010, Volume: 235, Issue:10

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipose Tissue; Animals; Base Sequence; China; Corticos

2010
Regulation by chronic-mild stress of glucocorticoids, monocyte chemoattractant protein-1 and adiposity in rats fed on a high-fat diet.
    Physiology & behavior, 2011, May-03, Volume: 103, Issue:2

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adipose Tissue, White; Adiposity; Angiotensinogen; Animals; C

2011
Effects of high-fat diet on insulin receptor function in rat hippocampus and the level of neuronal corticosterone.
    Life sciences, 2011, Mar-28, Volume: 88, Issue:13-14

    Topics: Animals; CA1 Region, Hippocampal; Corticosterone; Diet; Dietary Fats; Electrophoresis, Polyacrylamid

2011
Continuous 24-h nicotinic acid infusion in rats causes FFA rebound and insulin resistance by altering gene expression and basal lipolysis in adipose tissue.
    American journal of physiology. Endocrinology and metabolism, 2011, Volume: 300, Issue:6

    Topics: Adipose Tissue; Animals; Blotting, Western; Catecholamines; Corticosterone; Fatty Acids, Nonesterifi

2011
Dietary manipulation reveals an unexpected inverse relationship between fat mass and adipose 11β-hydroxysteroid dehydrogenase type 1.
    American journal of physiology. Endocrinology and metabolism, 2011, Volume: 300, Issue:6

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipose Tissue; Adiposity; Animals; Body Composition; C

2011
Is chromium from stainless steel utensils responsible for epidemic of type 2 diabetes?
    Medical hypotheses, 2011, Volume: 77, Issue:1

    Topics: Blood Glucose; Chromium; Corticosterone; Diabetes Mellitus, Type 2; Humans; India; Insulin; Insulin

2011
Association between Na⁺,K⁺-ATPase activity and the vulnerability/resilience to mood disorders induced by early life experience.
    Neurochemical research, 2011, Volume: 36, Issue:11

    Topics: Adaptation, Psychological; Amygdala; Animals; Animals, Newborn; Blood Glucose; Corticosterone; Depre

2011
A rodent model of rapid-onset diabetes induced by glucocorticoids and high-fat feeding.
    Disease models & mechanisms, 2012, Volume: 5, Issue:5

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipose Tissue; Adiposity; Animals; Body Composition; C

2012
Diet and exercise in an obese mouse fed a high-fat diet improve metabolic health and reverse perturbed sperm function.
    American journal of physiology. Endocrinology and metabolism, 2012, Apr-01, Volume: 302, Issue:7

    Topics: Acrosome Reaction; Animals; Blood Glucose; Body Composition; Cholesterol; Corticosterone; Diet, High

2012
Consumption of a high-fat diet rapidly exacerbates the development of fatty liver disease that occurs with chronically elevated glucocorticoids.
    American journal of physiology. Gastrointestinal and liver physiology, 2012, Apr-15, Volume: 302, Issue:8

    Topics: Adipose Tissue; Adrenal Glands; Animals; Atrophy; Blotting, Western; Body Weight; CD36 Antigens; Cel

2012
Timed high-fat diet resets circadian metabolism and prevents obesity.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2012, Volume: 26, Issue:8

    Topics: Animals; Circadian Rhythm; CLOCK Proteins; Corticosterone; Diet; Diet, High-Fat; Eating; Insulin Res

2012
Insulin sensitization with a peroxisome proliferator-activated receptor γ agonist prevents adrenocortical lipid infiltration and secretory changes induced by a high-sucrose diet.
    The Journal of endocrinology, 2012, Volume: 214, Issue:3

    Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Corticosterone; Dietary Sucrose; Energy Intake

2012
Peripubertal-onset but not adult-onset obesity increases IGF-I and drives development of lean mass, which may lessen the metabolic impairment in adult obesity.
    American journal of physiology. Endocrinology and metabolism, 2012, Nov-01, Volume: 303, Issue:9

    Topics: Adrenocorticotropic Hormone; Aging; Animals; Body Composition; Corticosterone; Diet, High-Fat; Disea

2012
Osteoblasts mediate the adverse effects of glucocorticoids on fuel metabolism.
    The Journal of clinical investigation, 2012, Volume: 122, Issue:11

    Topics: Animals; Anti-Inflammatory Agents; Corticosterone; Energy Metabolism; Glucocorticoids; Glucose Intol

2012
Comparison of the effects of acute and chronic psychological stress on metabolic features in rats.
    Journal of Zhejiang University. Science. B, 2012, Volume: 13, Issue:11

    Topics: Animals; Blood Glucose; Body Weight; Cholesterol; Corticosterone; Drinking; Eating; Insulin; Insulin

2012
The lipocalin-type prostaglandin D2 synthase knockout mouse model of insulin resistance and obesity demonstrates early hypothalamic-pituitary-adrenal axis hyperactivity.
    The Journal of endocrinology, 2013, Volume: 216, Issue:2

    Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Genotype; Hypercholesterolemia; Hyperglycemia;

2013
Early metabolic defects in dexamethasone-exposed and undernourished intrauterine growth restricted rats.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: Adipose Tissue; Analysis of Variance; Animals; Blood Glucose; Blotting, Western; Body Weights and Me

2012
Mineralocorticoid receptor activation induces insulin resistance through c-Jun N-terminal kinases in response to chronic corticosterone: cognitive implications.
    Journal of neuroendocrinology, 2013, Volume: 25, Issue:4

    Topics: Animals; Cognition Disorders; Corticosterone; Insulin; Insulin Resistance; JNK Mitogen-Activated Pro

2013
Propranolol reduces cognitive deficits, amyloid β levels, tau phosphorylation and insulin resistance in response to chronic corticosterone administration.
    The international journal of neuropsychopharmacology, 2013, Volume: 16, Issue:6

    Topics: Adrenergic beta-Antagonists; Amyloid beta-Peptides; Animals; Cognition Disorders; Corticosterone; Di

2013
Is programming of glucocorticoid receptor expression by prenatal dexamethasone in the rat secondary to metabolic derangement in adulthood?
    European journal of endocrinology, 2003, Volume: 148, Issue:1

    Topics: Animals; Appetite; Body Weight; Corticosterone; Dexamethasone; Female; Gene Expression; Glucocortico

2003
Light/dark cycle-dependent metabolic changes in adipose tissue of pinealectomized rats.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2004, Volume: 36, Issue:7

    Topics: Adipocytes; Adipose Tissue; Analysis of Variance; Animals; Blood Glucose; Body Weight; Circadian Rhy

2004
Intracerebroventricular administration of melanotan II increases insulin sensitivity of glucose disposal in mice.
    Diabetologia, 2005, Volume: 48, Issue:8

    Topics: alpha-MSH; Animals; Blood Glucose; Corticosterone; Fatty Acids, Nonesterified; Glucose; Glucose Clam

2005
Rats with steroid-induced polycystic ovaries develop hypertension and increased sympathetic nervous system activity.
    Reproductive biology and endocrinology : RB&E, 2005, Sep-07, Volume: 3

    Topics: Abdominal Fat; Adrenal Medulla; Adrenocorticotropic Hormone; Animals; Blood Pressure; Corticosterone

2005
Impact of transient correction of increased adrenocortical activity in hypothalamo-damaged, hyperadipose female rats.
    International journal of obesity (2005), 2006, Volume: 30, Issue:1

    Topics: Adipocytes; Adipose Tissue; Adiposity; Adrenal Cortex; Animals; Blood Glucose; Cells, Cultured; Cort

2006
Progressive alterations in the hypothalamic-pituitary-adrenal axis in the R6/2 transgenic mouse model of Huntington's disease.
    Human molecular genetics, 2006, May-15, Volume: 15, Issue:10

    Topics: Adrenocorticotropic Hormone; Adult; Animals; Body Fat Distribution; Bone Density; Corticosterone; Di

2006
Effects of dietary lipoic acid on plasma lipid, in vivo insulin sensitivity, metabolic response to corticosterone and in vitro lipolysis in broiler chickens.
    The British journal of nutrition, 2006, Volume: 95, Issue:6

    Topics: Adipose Tissue; Animals; Blood Glucose; Chickens; Corticosterone; Fatty Acids, Nonesterified; Female

2006
Distinct endocrine effects of chronic haloperidol or risperidone administration in male rats.
    Neuropharmacology, 2006, Volume: 51, Issue:7-8

    Topics: Adipose Tissue; Animals; Antipsychotic Agents; Appetite; Body Weight; Corticosterone; Diabetes Melli

2006
Insulin resistance and low sympathetic nerve activity in the Tsumura Suzuki obese diabetic mouse: a new model of spontaneous type 2 diabetes mellitus and obesity.
    Metabolism: clinical and experimental, 2006, Volume: 55, Issue:12

    Topics: Adiponectin; Adipose Tissue, Brown; Adrenal Glands; Animals; Corticosterone; Diabetes Mellitus, Type

2006
Intermittent hypoxia causes insulin resistance in lean mice independent of autonomic activity.
    American journal of respiratory and critical care medicine, 2007, Apr-15, Volume: 175, Issue:8

    Topics: Animals; Autonomic Nervous System; Body Mass Index; Corticosterone; Glucose; Glucose Clamp Technique

2007
Effects of the CRF1 receptor antagonist SSR125543 on energy balance and food deprivation-induced neuronal activation in obese Zucker rats.
    The Journal of endocrinology, 2007, Volume: 193, Issue:1

    Topics: Animals; Blood Glucose; Corticosterone; Corticotropin-Releasing Hormone; Energy Metabolism; Fatty Ac

2007
Maternal low-protein diet during lactation programmes body composition and glucose homeostasis in the adult rat offspring.
    The British journal of nutrition, 2007, Volume: 98, Issue:5

    Topics: Aging; Animals; Animals, Newborn; Blood Glucose; Body Composition; Catecholamines; Corticosterone; D

2007
Chemical gastric inhibitory polypeptide receptor antagonism protects against obesity, insulin resistance, glucose intolerance and associated disturbances in mice fed high-fat and cafeteria diets.
    Diabetologia, 2007, Volume: 50, Issue:8

    Topics: Adiponectin; Animals; Blood Glucose; Body Weight; Corticosterone; Dietary Fats; Eating; Gastric Inhi

2007
Peripheral mechanisms contributing to the glucocorticoid hypersensitivity in proopiomelanocortin null mice treated with corticosterone.
    The Journal of endocrinology, 2007, Volume: 194, Issue:1

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipose Tissue; Animals; Corticosterone; Glucocorticoid

2007
Effect of reversing dark-light cycles on normal diurnal variation and related metabolic disturbance in rats.
    The Chinese journal of physiology, 2007, Apr-30, Volume: 50, Issue:2

    Topics: Adipocytes; Animals; Blood Glucose; Circadian Rhythm; Corticosterone; Drinking; Eating; Fatty Acids,

2007
Diabetic pregnancy in rats leads to impaired glucose metabolism in offspring involving tissue-specific dysregulation of 11beta-hydroxysteroid dehydrogenase type 1 expression.
    Life sciences, 2007, Aug-09, Volume: 81, Issue:9

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipose Tissue; Animals; Blood Glucose; Corticosterone;

2007
GIP receptor antagonism reverses obesity, insulin resistance, and associated metabolic disturbances induced in mice by prolonged consumption of high-fat diet.
    American journal of physiology. Endocrinology and metabolism, 2007, Volume: 293, Issue:6

    Topics: Adipokines; Adipose Tissue; Animals; Anti-Obesity Agents; Blood Glucose; Body Weight; Corticosterone

2007
Increased hypothalamic-pituitary-adrenal axis activity and hepatic insulin resistance in low-birth-weight rats.
    American journal of physiology. Endocrinology and metabolism, 2007, Volume: 293, Issue:5

    Topics: Adrenocorticotropic Hormone; Animals; Animals, Newborn; Cholesterol; Corticosterone; Fasting; Female

2007
Postnatal programming of glucocorticoid metabolism in rats modulates high-fat diet-induced regulation of visceral adipose tissue glucocorticoid exposure and sensitivity and adiponectin and proinflammatory adipokines gene expression in adulthood.
    Diabetes, 2008, Volume: 57, Issue:3

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipokines; Adiponectin; Adipose Tissue; Aging; Animals

2008
Sub-chronic administration of the 11beta-HSD1 inhibitor, carbenoxolone, improves glucose tolerance and insulin sensitivity in mice with diet-induced obesity.
    Biological chemistry, 2008, Volume: 389, Issue:4

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Blood Glucose; Body Weight; Carbenoxolone; Cor

2008
Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons.
    Nature neuroscience, 2008, Volume: 11, Issue:3

    Topics: Animals; Brain Diseases, Metabolic; Cell Differentiation; Cell Proliferation; Cognition Disorders; C

2008
Evidence for a role of glucocorticoids in the development of insulin resistance after ischaemic limb injury in the rat.
    The Journal of endocrinology, 1980, Volume: 86, Issue:2

    Topics: Adrenal Cortex; Androstanols; Animals; Blood Glucose; Corticosterone; Dihydrotestosterone; Hindlimb;

1980
Corticosterone-induced insulin resistance is not associated with alterations of insulin receptor number and kinase activity in chicken kidney.
    General and comparative endocrinology, 1994, Volume: 96, Issue:3

    Topics: Animals; Binding, Competitive; Blood Glucose; Cell Membrane; Chickens; Corticosterone; Cytoplasm; In

1994
Acute dexfenfluramine administration normalizes glucose tolerance in rats with insulin-deficient diabetes.
    European journal of clinical investigation, 1994, Volume: 24, Issue:3

    Topics: Animals; Blood Glucose; Corticosterone; Diabetes Mellitus, Experimental; Dose-Response Relationship,

1994
Involvement of non-esterified fatty acid oxidation in glucocorticoid-induced peripheral insulin resistance in vivo in rats.
    Diabetologia, 1993, Volume: 36, Issue:10

    Topics: Animals; Blood Glucose; Carnitine O-Palmitoyltransferase; Corticosterone; Epoxy Compounds; Fatty Aci

1993
Circadian neuroendocrine role in age-related changes in body fat stores and insulin sensitivity of the male Sprague-Dawley rat.
    Chronobiology international, 1993, Volume: 10, Issue:4

    Topics: Adipose Tissue; Aging; Animals; Blood Glucose; Circadian Rhythm; Corticosterone; Insulin; Insulin Re

1993
Dietary rat models in which the development of hypertriglyceridemia and that of insulin resistance are dissociated.
    Metabolism: clinical and experimental, 1995, Volume: 44, Issue:12

    Topics: Animals; Blood Glucose; Corticosterone; Dietary Carbohydrates; Dietary Fats; Eating; Fasting; Fatty

1995
Imprinting of female offspring with testosterone results in insulin resistance and changes in body fat distribution at adult age in rats.
    The Journal of clinical investigation, 1998, Jan-01, Volume: 101, Issue:1

    Topics: Adipose Tissue; Adrenocorticotropic Hormone; Animals; Blood Glucose; Corticosterone; Fatty Acids, No

1998
Environmental stress modifies glycemic control and diabetes onset in type 2 diabetes prone Otsuka Long Evans Tokushima Fatty (OLETF) rats.
    Physiology & behavior, 2000, Volume: 68, Issue:4

    Topics: Animals; Blood Glucose; Catecholamines; Corticosterone; Diabetes Mellitus, Type 2; Eating; Glycated

2000
Hypertension and insulin resistant models have divergent propensities to learned helpless behavior in rodents.
    American journal of hypertension, 2000, Volume: 13, Issue:6 Pt 1

    Topics: Animals; Behavior, Animal; Biomarkers; Blood Pressure; Comorbidity; Corticosterone; Depression; Fema

2000
Excess portal venous long-chain fatty acids induce syndrome X via HPA axis and sympathetic activation.
    American journal of physiology. Endocrinology and metabolism, 2000, Volume: 279, Issue:6

    Topics: Animals; Blood Pressure; Caprylates; Corticosterone; Epinephrine; Glucose Tolerance Test; Heart Rate

2000
Endocrine regulation of G-protein subunit production in an animal model of type 2 diabetes mellitus.
    The Journal of endocrinology, 2001, Volume: 168, Issue:3

    Topics: Adipocytes; Animals; Blood Glucose; Cell Culture Techniques; Corticosterone; Diabetes Mellitus, Expe

2001
Glucocorticoid-induced insulin resistance associates with activation of protein kinase C isoforms.
    Cellular signalling, 2001, Volume: 13, Issue:3

    Topics: Adipocytes; Animals; Biological Transport; Cell Membrane; Cell Separation; Cells, Cultured; Corticos

2001
Maternal endotoxemia results in obesity and insulin resistance in adult male offspring.
    Endocrinology, 2001, Volume: 142, Issue:6

    Topics: Adipose Tissue; Animals; Blood Glucose; Body Composition; Brain Chemistry; Carrier Proteins; Cortico

2001
A transgenic model of visceral obesity and the metabolic syndrome.
    Science (New York, N.Y.), 2001, Dec-07, Volume: 294, Issue:5549

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Abdomen; Adipocytes; Adipose Tissue; Animals; Body Comp

2001
The effects of high-fat diet on exercise-induced changes in metabolic parameters in Zucker fa/fa rats.
    Metabolism: clinical and experimental, 2002, Volume: 51, Issue:6

    Topics: Animals; Blood Glucose; Body Weight; Cell Separation; Cells, Cultured; Corticosterone; Dietary Fats;

2002
Changes in insulin sensitivity from stress during repetitive sampling in anesthetized rats.
    The American journal of physiology, 1992, Volume: 262, Issue:6 Pt 2

    Topics: Adrenocorticotropic Hormone; Animals; Blood Glucose; Blood Specimen Collection; Blood Volume; Cortic

1992
The effects of testosterone on insulin sensitivity in male rats.
    Acta physiologica Scandinavica, 1992, Volume: 146, Issue:4

    Topics: Animals; Corticosterone; Deoxyglucose; Glucose; Glycogen; Insulin Resistance; Kinetics; Male; Muscle

1992
Amylin-induced in vivo insulin resistance in conscious rats: the liver is more sensitive to amylin than peripheral tissues.
    Diabetologia, 1991, Volume: 34, Issue:4

    Topics: Amyloid; Animals; Cell Line; Corticosterone; Epinephrine; Glucagon; Glucose; Glucose Clamp Technique

1991
Diet-induced type II diabetes in C57BL/6J mice.
    Diabetes, 1988, Volume: 37, Issue:9

    Topics: Animals; Blood Glucose; Corticosterone; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2;

1988
Decreased binding of insulin to its receptors in rats with hormone induced insulin resistance.
    Biochemical and biophysical research communications, 1973, Aug-06, Volume: 53, Issue:3

    Topics: Animals; Blood Glucose; Cell Membrane; Corticosterone; Dose-Response Relationship, Drug; Female; Glu

1973