Page last updated: 2024-11-06

corticosterone and Epilepsy, Absence

corticosterone has been researched along with Epilepsy, Absence in 4 studies

Epilepsy, Absence: A seizure disorder usually occurring in childhood characterized by rhythmic electrical brain discharges of generalized onset. Clinical features include a sudden cessation of ongoing activity usually without loss of postural tone. Rhythmic blinking of the eyelids or lip smacking frequently accompanies the SEIZURES. The usual duration is 5-10 seconds, and multiple episodes may occur daily. Juvenile absence epilepsy is characterized by the juvenile onset of absence seizures and an increased incidence of myoclonus and tonic-clonic seizures. (Menkes, Textbook of Child Neurology, 5th ed, p736)

Research Excerpts

ExcerptRelevanceReference
" Metyrapone, an inhibitor of corticosterone synthesis, completely abolished seizures in GAERS, and seizures remained suppressed for >2 h."8.31Metyrapone abolishes spike-wave discharge seizures in genetic absence epilepsy rats from Strasbourg by reducing stress hormones. ( Dezsi, G; Harris, G; Jones, NC; O'Brien, TJ; Ozturk, E; Paul, C, 2023)
"anxiety and depression) are commonly observed in patients with epilepsy and induce seizure aggravation."5.72Transcranial Direct Current Stimulation Reduces Anxiety, Depression and Plasmatic Corticosterone in a Rat Model of Atypical Generalized Epilepsy. ( Antunes, GF; Castro, MC; Germann, J; Gomes, GCV; Gouveia, FV; Martinez, RCR; Oliveira, CC; Pinto, TRC; Valle, AC, 2022)
" Metyrapone, an inhibitor of corticosterone synthesis, completely abolished seizures in GAERS, and seizures remained suppressed for >2 h."4.31Metyrapone abolishes spike-wave discharge seizures in genetic absence epilepsy rats from Strasbourg by reducing stress hormones. ( Dezsi, G; Harris, G; Jones, NC; O'Brien, TJ; Ozturk, E; Paul, C, 2023)
"anxiety and depression) are commonly observed in patients with epilepsy and induce seizure aggravation."1.72Transcranial Direct Current Stimulation Reduces Anxiety, Depression and Plasmatic Corticosterone in a Rat Model of Atypical Generalized Epilepsy. ( Antunes, GF; Castro, MC; Germann, J; Gomes, GCV; Gouveia, FV; Martinez, RCR; Oliveira, CC; Pinto, TRC; Valle, AC, 2022)
"However, for childhood absence epilepsy, a nonconvulsive type of epilepsy, direct evidence for corticosteroid seizure modulation is lacking."1.32Corticosterone increases spike-wave discharges in a dose- and time-dependent manner in WAG/Rij rats. ( Schridde, U; van Luijtelaar, G, 2004)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Gouveia, FV1
Germann, J1
Oliveira, CC1
Castro, MC1
Antunes, GF1
Gomes, GCV1
Pinto, TRC1
Martinez, RCR1
Valle, AC1
Dezsi, G1
Ozturk, E1
Harris, G1
Paul, C1
O'Brien, TJ1
Jones, NC1
Tolmacheva, EA1
Oitzl, MS1
van Luijtelaar, G2
Schridde, U1

Other Studies

4 other studies available for corticosterone and Epilepsy, Absence

ArticleYear
Transcranial Direct Current Stimulation Reduces Anxiety, Depression and Plasmatic Corticosterone in a Rat Model of Atypical Generalized Epilepsy.
    Neuroscience, 2022, 01-01, Volume: 480

    Topics: Animals; Anxiety; Corticosterone; Depression; Epilepsy, Absence; Humans; Rats; Rats, Wistar; Transcr

2022
Metyrapone abolishes spike-wave discharge seizures in genetic absence epilepsy rats from Strasbourg by reducing stress hormones.
    Epilepsia, 2023, Volume: 64, Issue:6

    Topics: Animals; Corticosterone; Desoxycorticosterone; Disease Models, Animal; Electroencephalography; Epile

2023
Stress, glucocorticoids and absences in a genetic epilepsy model.
    Hormones and behavior, 2012, Volume: 61, Issue:5

    Topics: Animals; Circadian Rhythm; Corticosterone; Disease Models, Animal; Electric Stimulation; Electroence

2012
Corticosterone increases spike-wave discharges in a dose- and time-dependent manner in WAG/Rij rats.
    Pharmacology, biochemistry, and behavior, 2004, Volume: 78, Issue:2

    Topics: Action Potentials; Animals; Corticosterone; Dose-Response Relationship, Drug; Epilepsy, Absence; Mal

2004