corticosterone has been researched along with Endotoxin Shock in 44 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " We examine whether the decrease in leptin induced by starvation increases susceptibility to lipopolysaccharide (LPS)- and tumor necrosis factor (TNF)-induced lethality." | 7.70 | Reduced leptin levels in starvation increase susceptibility to endotoxic shock. ( Faggioni, R; Feingold, KR; Grunfeld, C; Moser, A, 2000) |
| "Previous studies established that naloxone reverses hypotension in endotoxin, hemorrhagic, and spinal shock." | 7.67 | Endotoxin shock: prevented by naloxone in intact but not hypophysectomized rats. ( Davis, SD; Kendall, JW; McDonald, WJ; Potter, DM, 1984) |
| " Compared to healthy subjects, patients with sepsis had elevated levels of 11-desoxycorticosterone and 11-desoxycortisol, consistent with activation of both glucocorticoid and mineralocorticoid pathways." | 5.51 | Corticotropin-stimulated steroid profiles to predict shock development and mortality in sepsis: From the HYPRESS study. ( Annane, D; Bogatsch, H; Briegel, J; Frank, S; Hinske, LC; Keh, D; Lange, D; Lindner, JM; Möhnle, P; Vetter, AC; Vogeser, M, 2022) |
| "The aim of this study was to determine the effects of previous administration of metyrapone (met) on the acute lung injury (ALI) induced by caecal ligation and puncture (CLP) and to explore met's relationship with endogenous glucocorticoids (GCs) as measured by inflammatory, oxidative and functional parameters." | 3.81 | Inhibition of endogenous glucocorticoid synthesis aggravates lung injury triggered by septic shock in rats. ( Incerpi, EK; Oliveira, LM; Pereira, EM; Soncini, R, 2015) |
| " We examine whether the decrease in leptin induced by starvation increases susceptibility to lipopolysaccharide (LPS)- and tumor necrosis factor (TNF)-induced lethality." | 3.70 | Reduced leptin levels in starvation increase susceptibility to endotoxic shock. ( Faggioni, R; Feingold, KR; Grunfeld, C; Moser, A, 2000) |
| "Previous studies established that naloxone reverses hypotension in endotoxin, hemorrhagic, and spinal shock." | 3.67 | Endotoxin shock: prevented by naloxone in intact but not hypophysectomized rats. ( Davis, SD; Kendall, JW; McDonald, WJ; Potter, DM, 1984) |
| "Sepsis and septic shock are commonly present in the ICU and accompanied by significant morbidity, mortality, and cost." | 1.43 | Mortality of Septic Mice Strongly Correlates With Adrenal Gland Inflammation. ( Bornstein, S; Dröse, S; Heerdegen, L; Jennewein, C; Kanczkowski, W; Kantharajah, A; Scheller, B; Tran, N; Zacharowski, K, 2016) |
| "When endotoxic shock was induced, the LPS-induced hypoglycemia developed in WN rats was abolished in UN animals, and both ACTH and TNF plasma concentrations after endotoxin, albeit significantly (p < 0." | 1.31 | Metabolic, neuroendocrine and immune functions in basal conditions and during the acute-phase response to endotoxic shock in undernourished rats. ( Chisari, AN; Corró, L; Gaillard, RC; Giovambattista, A; Spinedi, E, 2000) |
| "Corticosterone and AA-2414 treatment may attenuate the LPS-induced production of eicosanoids, and enhance the LPS-induced ODC activation." | 1.30 | Effects of eicosanoids on lipopolysaccharide-induced ornithine decarboxylase activity and polyamine metabolism in the mouse liver. ( Hamana, K; Matsuzaki, S; Matsuzaki, Y; Mori, M; Nagamine, T; Sugimoto, H, 1997) |
| " The CS response showed an earlier onset, prolonged (greater than 12 hr) duration, and a broader dose-response pattern." | 1.28 | Effect of gram-negative endotoxin on levels of serum corticosterone, TNF alpha, circulating blood cells, and the survival of rats. ( Feuerstein, G; Hallenbeck, JM; Perera, PY; Rabinovici, R; Vanatta, B; Vogel, SN, 1990) |
| "Endotoxic shock was associated with marked increases in plasma catecholamine levels, with epinephrine levels showing the greatest change, and significant though less pronounced increases in corticosterone." | 1.27 | Effects of naloxone and thyrotropin-releasing hormone on plasma catecholamines, corticosterone, and arterial pressure in normal and endotoxemic rats. ( Holaday, JW; Lake, CR; Long, JB; Reid, AA, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (45.45) | 18.7374 |
| 1990's | 12 (27.27) | 18.2507 |
| 2000's | 8 (18.18) | 29.6817 |
| 2010's | 3 (6.82) | 24.3611 |
| 2020's | 1 (2.27) | 2.80 |
| Authors | Studies |
|---|---|
| Briegel, J | 1 |
| Möhnle, P | 1 |
| Keh, D | 1 |
| Lindner, JM | 1 |
| Vetter, AC | 1 |
| Bogatsch, H | 1 |
| Lange, D | 1 |
| Frank, S | 1 |
| Hinske, LC | 1 |
| Annane, D | 1 |
| Vogeser, M | 1 |
| Quatrini, L | 1 |
| Wieduwild, E | 1 |
| Guia, S | 1 |
| Bernat, C | 1 |
| Glaichenhaus, N | 1 |
| Vivier, E | 1 |
| Ugolini, S | 1 |
| Incerpi, EK | 1 |
| Oliveira, LM | 1 |
| Pereira, EM | 1 |
| Soncini, R | 1 |
| Jennewein, C | 1 |
| Tran, N | 1 |
| Kanczkowski, W | 1 |
| Heerdegen, L | 1 |
| Kantharajah, A | 1 |
| Dröse, S | 1 |
| Bornstein, S | 1 |
| Scheller, B | 1 |
| Zacharowski, K | 1 |
| Agelaki, S | 1 |
| Tsatsanis, C | 1 |
| Gravanis, A | 1 |
| Margioris, AN | 1 |
| Ocasio, FM | 1 |
| Jiang, Y | 1 |
| House, SD | 1 |
| Chang, SL | 1 |
| Sánchez, O | 1 |
| Viladrich, M | 1 |
| Ramírez, I | 1 |
| Soley, M | 1 |
| Cai, L | 1 |
| Ji, A | 1 |
| de Beer, FC | 1 |
| Tannock, LR | 1 |
| van der Westhuyzen, DR | 1 |
| Jones, WR | 1 |
| Keri, G | 1 |
| Parameswaran, V | 2 |
| Trunkey, DD | 2 |
| Ramachandran, J | 2 |
| Davis, SD | 1 |
| McDonald, WJ | 1 |
| Kendall, JW | 1 |
| Potter, DM | 1 |
| Catalano, RD | 1 |
| Uzunova, A | 1 |
| Petkova, M | 4 |
| Grigorova, R | 3 |
| Uzunov, P | 1 |
| Savu, L | 1 |
| Zouaghi, H | 1 |
| Carli, A | 2 |
| Nunez, EA | 1 |
| Chorinchath, BB | 1 |
| Kong, LY | 1 |
| Mao, L | 1 |
| McCallum, RE | 1 |
| Florquin, S | 1 |
| Goldman, M | 1 |
| Trgovcich, J | 1 |
| Ryman, K | 1 |
| Extrom, P | 1 |
| Eldridge, JC | 1 |
| Aronson, JF | 1 |
| Johnston, RE | 1 |
| Matsuzaki, Y | 1 |
| Sugimoto, H | 1 |
| Hamana, K | 1 |
| Nagamine, T | 1 |
| Matsuzaki, S | 1 |
| Mori, M | 1 |
| Gallily, R | 1 |
| Yamin, A | 1 |
| Waksmann, Y | 1 |
| Ovadia, H | 1 |
| Weidenfeld, J | 1 |
| Bar-Joseph, A | 1 |
| Biegon, A | 1 |
| Mechoulam, R | 1 |
| Shohami, E | 1 |
| Kishikawa, H | 1 |
| Lawrence, DA | 1 |
| Giovambattista, A | 1 |
| Chisari, AN | 1 |
| Corró, L | 1 |
| Gaillard, RC | 1 |
| Spinedi, E | 1 |
| Faggioni, R | 1 |
| Moser, A | 1 |
| Feingold, KR | 1 |
| Grunfeld, C | 1 |
| Maitra, SR | 1 |
| Wang, S | 1 |
| Brathwaite, CE | 1 |
| El-Maghrabi, MR | 1 |
| Quan, N | 1 |
| Avitsur, R | 1 |
| Stark, JL | 1 |
| He, L | 1 |
| Shah, M | 1 |
| Caligiuri, M | 1 |
| Padgett, DA | 1 |
| Marucha, PT | 1 |
| Sheridan, JF | 1 |
| Ramachandra, RN | 1 |
| Sehon, AH | 1 |
| Berczi, I | 1 |
| Bertini, R | 1 |
| Mengozzi, M | 1 |
| Bianchi, M | 1 |
| Sipe, JD | 1 |
| Ghezzi, P | 1 |
| Ilieva, T | 1 |
| Tsoncheva, A | 1 |
| Morikage, T | 1 |
| Mizushima, Y | 1 |
| Yano, S | 1 |
| Feuerstein, G | 1 |
| Hallenbeck, JM | 1 |
| Vanatta, B | 1 |
| Rabinovici, R | 1 |
| Perera, PY | 1 |
| Vogel, SN | 1 |
| Gardey, C | 1 |
| Thiroux, G | 1 |
| Christeff, N | 1 |
| Zuckerman, SH | 1 |
| Shellhaas, J | 1 |
| Butler, LD | 1 |
| Witek-Janusek, L | 1 |
| Long, JB | 1 |
| Lake, CR | 1 |
| Reid, AA | 1 |
| Holaday, JW | 1 |
| Novelli, GP | 1 |
| Nikolov, N | 1 |
| Akiyama, M | 1 |
| Shirakawa, T | 1 |
| Hattori, N | 1 |
| Takahashi, K | 1 |
| Azuma, K | 1 |
| Totsuka, M | 1 |
| Hayasaka, H | 1 |
| Nicolov, N | 1 |
| Jordanov, J | 1 |
| Schauer, A | 1 |
| Gielow, L | 1 |
| White, FN | 1 |
| Gold, EM | 1 |
| Vaughn, DL | 1 |
| Kurata, S | 1 |
| Hirose, Y | 1 |
| Abe, Y | 1 |
| Schildt, BE | 1 |
| Rasková, H | 1 |
| Masek, K | 1 |
| Linèt, O | 1 |
| Jeffries, CD | 1 |
| Wilkins, J | 1 |
| Alho, A | 1 |
| Latour, JG | 1 |
| Renaud, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Placebo-controlled, Randomised, Double-blind Study to Investigate the Efficacy and Safety of Low Dose Hydrocortisone to Prevent the Development of Septic Shock in Patients With Severe Sepsis[NCT00670254] | Phase 3 | 380 participants (Actual) | Interventional | 2009-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for corticosterone and Endotoxin Shock
| Article | Year |
|---|---|
Immunoregulatory mechanisms of T-cell-dependent shock induced by a bacterial superantigen in mice.
Topics: Animals; Clonal Anergy; Corticosterone; Cytokines; Enterotoxins; Inflammation; Interleukin-10; Lymph | 1996 |
The role of the RES in shock states.
Topics: Adrenocorticotropic Hormone; Animals; Burns; Corticosterone; Depression, Chemical; Dogs; Humans; In | 1971 |
Lysosomal functions in circulatory shock.
Topics: Autolysis; Cell Survival; Cells; Corticosterone; Glucuronidase; Humans; Hydrolases; Kidney Tubules; | 1971 |
1 trial available for corticosterone and Endotoxin Shock
| Article | Year |
|---|---|
Corticotropin-stimulated steroid profiles to predict shock development and mortality in sepsis: From the HYPRESS study.
Topics: Adrenocorticotropic Hormone; Adult; Chromatography, Liquid; Corticosterone; Cortodoxone; Desoxycorti | 2022 |
40 other studies available for corticosterone and Endotoxin Shock
| Article | Year |
|---|---|
Host resistance to endotoxic shock requires the neuroendocrine regulation of group 1 innate lymphoid cells.
Topics: Animals; Corticosterone; Disease Resistance; Glucocorticoids; Interferon-gamma; Interleukin-10; Lipo | 2017 |
Inhibition of endogenous glucocorticoid synthesis aggravates lung injury triggered by septic shock in rats.
Topics: Acute Lung Injury; Animals; Corticosterone; Disease Models, Animal; Down-Regulation; Enzyme Inhibito | 2015 |
Mortality of Septic Mice Strongly Correlates With Adrenal Gland Inflammation.
Topics: Adrenal Glands; Adrenal Insufficiency; Adrenocorticotropic Hormone; Animals; Cecum; Corticosterone; | 2016 |
Corticotropin-releasing hormone augments proinflammatory cytokine production from macrophages in vitro and in lipopolysaccharide-induced endotoxin shock in mice.
Topics: Animals; Cell Line; Corticosterone; Corticotropin-Releasing Hormone; Cytokines; Hypothalamo-Hypophys | 2002 |
Chronic morphine accelerates the progression of lipopolysaccharide-induced sepsis to septic shock.
Topics: Animals; Antithrombin III; Blood Pressure; Body Temperature; Cell Communication; Corticosterone; Dis | 2004 |
Liver injury after an aggressive encounter in male mice.
Topics: Aggression; Animals; Cell Death; Corticosterone; Epidermal Growth Factor; ErbB Receptors; Hepatocyte | 2007 |
SR-BI protects against endotoxemia in mice through its roles in glucocorticoid production and hepatic clearance.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Cholesterol Esters; Corticosterone; Endotoxemi | 2008 |
Septic abortion: new aspects of management.
Topics: Abortion, Septic; Acute Kidney Injury; Anti-Bacterial Agents; Corticosterone; Female; Humans; Hyster | 1967 |
Effects of septic shock plasma on adrenocortical cell function.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Cells, Cultured; Corticosterone; Culture Media | 1981 |
Endotoxin shock: prevented by naloxone in intact but not hypophysectomized rats.
Topics: Animals; beta-Endorphin; Blood Pressure; Corticosterone; Endorphins; Hypophysectomy; Hypotension; Ma | 1984 |
Mechanisms of adrenocortical depression during Escherichia coli shock.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Bucladesine; Cells, Cultured; Corticosterone; | 1984 |
Effect of endotoxin shock on catecholamines and corticosterone level in neonatally thymectomized rats.
Topics: Animals; Animals, Newborn; Catecholamines; Corticosterone; Male; Rats; Rats, Inbred Strains; Shock, | 1981 |
Serum depletion of corticosteroid binding activities, an early marker of human septic shock.
Topics: Corticosterone; Humans; Hydrocortisone; Inflammation; Kinetics; Progesterone; Shock, Septic; Transco | 1981 |
Age-associated differences in TNF-alpha and nitric oxide production in endotoxic mice.
Topics: Aging; Animals; Cells, Cultured; Corticosterone; Dexamethasone; Glucocorticoids; Interferon-gamma; I | 1996 |
Sindbis virus infection of neonatal mice results in a severe stress response.
Topics: Adrenocorticotropic Hormone; Alphavirus Infections; Animals; Animals, Newborn; Brain; Corticosterone | 1997 |
Effects of eicosanoids on lipopolysaccharide-induced ornithine decarboxylase activity and polyamine metabolism in the mouse liver.
Topics: Alprostadil; Animals; Benzoquinones; Blotting, Northern; Corticosterone; Eicosanoids; Enzyme Inducti | 1997 |
Protection against septic shock and suppression of tumor necrosis factor alpha and nitric oxide production by dexanabinol (HU-211), a nonpsychotropic cannabinoid.
Topics: Animals; Blood Pressure; Cell Line; Corticosterone; Dronabinol; Female; Lipopolysaccharides; Macroph | 1997 |
Differential production of interleukin-6 in the brain and spleen of mice treated with lipopolysaccharide in the presence and absence of lead.
Topics: Animals; Blotting, Northern; Brain; Corticosterone; Female; Gene Expression; Hypothalamo-Hypophyseal | 1998 |
Metabolic, neuroendocrine and immune functions in basal conditions and during the acute-phase response to endotoxic shock in undernourished rats.
Topics: Acute-Phase Reaction; Adipocytes; Adrenocorticotropic Hormone; Aging; Animals; Blood Glucose; Cortic | 2000 |
Reduced leptin levels in starvation increase susceptibility to endotoxic shock.
Topics: Animals; Blood Glucose; Corticosterone; Cytokines; Disease Susceptibility; Fasting; Female; Leptin; | 2000 |
Alterations in glucose-6-phosphatase gene expression in sepsis.
Topics: Animals; Blotting, Northern; Corticosterone; Disease Models, Animal; Gene Expression Regulation, Enz | 2000 |
Social stress increases the susceptibility to endotoxic shock.
Topics: Animals; Cell Division; Cell Separation; Corticosterone; Disease Models, Animal; Disease Susceptibil | 2001 |
Neuro-hormonal host defence in endotoxin shock.
Topics: Adrenalectomy; Animals; Corticosterone; Dexamethasone; Disease Susceptibility; Dose-Response Relatio | 1992 |
Chlorpromazine protection against interleukin-1 and tumor necrosis factor-mediated activities in vivo.
Topics: Animals; Chlorpromazine; Corticosterone; Eating; Fibrinogen; Inflammation; Interleukin-1; Male; Mice | 1991 |
[The content of corticosterone, adrenaline and noradrenaline in the organs of rats in endotoxic shock and being treated with vitamin E].
Topics: Animals; Blood Pressure; Corticosterone; Drug Evaluation, Preclinical; Endotoxins; Epinephrine; Esch | 1991 |
Prevention of bacterial infection and LPS-induced lethality by interleukin-1 alpha in mice.
Topics: Animals; Corticosterone; Drug Evaluation, Preclinical; Immunologic Factors; Interleukin-1; Klebsiell | 1991 |
Effect of gram-negative endotoxin on levels of serum corticosterone, TNF alpha, circulating blood cells, and the survival of rats.
Topics: Animals; Blood Platelets; Corticosterone; Endotoxins; Escherichia coli; Hematocrit; Leukocytes; Lipo | 1990 |
Unexpected hyperactivity of myocardial adenylate cyclase system in endotoxic male rats.
Topics: 17-alpha-Hydroxyprogesterone; Adenylyl Cyclases; Androstenedione; Animals; Corticosterone; Dose-Resp | 1990 |
Differential regulation of lipopolysaccharide-induced interleukin 1 and tumor necrosis factor synthesis: effects of endogenous and exogenous glucocorticoids and the role of the pituitary-adrenal axis.
Topics: Adjuvants, Immunologic; Animals; Cells, Cultured; Corticosterone; Dexamethasone; Endothelium, Vascul | 1989 |
Pituitary-adrenal response to bacterial endotoxin in developing rats.
Topics: Adrenocorticotropic Hormone; Aging; Animals; Animals, Newborn; Blood Glucose; Corticosterone; Diseas | 1988 |
Effects of naloxone and thyrotropin-releasing hormone on plasma catecholamines, corticosterone, and arterial pressure in normal and endotoxemic rats.
Topics: Animals; Blood Glucose; Blood Pressure; Catecholamines; Corticosterone; Endotoxins; Escherichia coli | 1986 |
Changes in the glucocorticoids secretion during endotoxin shock and antioxidants treatment.
Topics: Adrenal Glands; Animals; Antioxidants; Corticosterone; Endotoxins; Escherichia coli; Rats; Rats, Inb | 1987 |
[Adrenal circulation of rabbits in hemorrhagic and endotoxin shock].
Topics: Adrenal Glands; Animals; Blood Pressure; Corticosterone; Electrolytes; Hydrogen-Ion Concentration; L | 1987 |
Changes in the suprarenal function during endotoxin shock.
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Animals; Corticosterone; Male; Rats; Rats, Inbred Strains | 1986 |
[Increase of histidine decarboxylase activity in endotoxic shock].
Topics: Animals; Capillaries; Carboxy-Lyases; Corticosterone; Depression, Chemical; Female; Glucocorticoids; | 1967 |
Renin-aldosterone system in endotoxin shock in the dog.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Blood Pressure; C | 1967 |
[Limited experience in adrenocortical function tests in infants].
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Corticosterone; Exchang | 1968 |
Non-specific resistance induced by palmitoylethanolamide.
Topics: Adrenal Glands; Adrenalectomy; Animals; Corticosterone; Injections, Intravenous; Male; Mice; Mononuc | 1972 |
Effect of exogenous steroids and inhibitors of steroidogenesis on endotoxin shock.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Aminoglutethimide; Androstenedione; Animals; Butanones; Cor | 1973 |
Prevention by glucocorticoids of various blood parameter changes following surgical intervention and endotoxin administration in the rat.
Topics: Adrenal Insufficiency; Animals; Blood Coagulation; Blood Coagulation Disorders; Blood Coagulation Te | 1969 |