Page last updated: 2024-11-06

corticosterone and Drug Withdrawal Symptoms

corticosterone has been researched along with Drug Withdrawal Symptoms in 154 studies

Research Excerpts

ExcerptRelevanceReference
" Clonazepam, a commonly prescribed benzodiazepine, has been increasingly used as a countermeasure to cocaine side-effects, including sleep reduction and anxiety."7.96Combined cocaine and clonazepam administration induces REM sleep loss and anxiety-like withdrawal behaviors in rats. ( Andersen, ML; Dokkedal-Silva, V; Galduróz, JCF; Tufik, S, 2020)
" This study aims to investigate the potential effects of hydrogen-rich saline (HRS) administration on naloxone-precipitated withdrawal symptoms and morphine withdrawal-induced anxiety-like behaviors."7.85Hydrogen-rich saline attenuates anxiety-like behaviors in morphine-withdrawn mice. ( Cong, B; Gong, M; Guo, H; Hui, R; Ma, C; Shen, Q; Wang, J; Wen, D; Zhao, P, 2017)
"The aim of the present study was to investigate the effects of the selective agonists of the corticotropin-releasing factor (CRF) 2 receptor, urocortin 2 (UCN 2) and urocortin 3 (UCN 3), on the anxiety- and depression-like signs induced by acute nicotine withdrawal in mice."7.83Selective CRF2 receptor agonists ameliorate the anxiety- and depression-like state developed during chronic nicotine treatment and consequent acute withdrawal in mice. ( Bagosi, Z; Balangó, B; Bokor, P; Buzás, A; Csabafi, K; Jászberényi, M; Palotai, M; Pintér, D; Simon, B; Szabó, G, 2016)
" Basally, HRs display lower anxiety-like behavior compared to LRs along with higher neuropeptide Y (NPY) mRNA in the amygdala and the hippocampus."7.77Effects of a selective Y2R antagonist, JNJ-31020028, on nicotine abstinence-related social anxiety-like behavior, neuropeptide Y and corticotropin releasing factor mRNA levels in the novelty-seeking phenotype. ( Aydin, C; Isgor, C; Oztan, O, 2011)
"Acute amphetamine administration activates monoaminergic pathways and increases systemic corticosterone, both of which influence anxiety states and adult dentate gyrus neurogenesis."7.76Withdrawal from chronic amphetamine produces persistent anxiety-like behavior but temporally-limited reductions in monoamines and neurogenesis in the adult rat dentate gyrus. ( Barr, JL; Forster, GL; Renner, KJ, 2010)
" Eight hours after ethanol withdrawal, anxiety-like behaviour was tested in the elevated plus-maze, blood corticosterone levels were measured, and expression level of markers of neuronal activity and plasticity, c-fos and zif268, was assessed."7.73Previous experience of ethanol withdrawal increases withdrawal-induced c-fos expression in limbic areas, but not withdrawal-induced anxiety and prevents withdrawal-induced elevations in plasma corticosterone. ( Borlikova, GG; Le Merrer, J; Stephens, DN, 2006)
") was challenged 18 hr after infusion was stopped, and the withdrawal was evaluated by plasma corticosterone (PCS) increase, diarrhea and body weight loss."7.69Possible involvement of the total amount of morphine infused in the development of acute morphine dependence in rats. ( Fukunaga, Y; Inoue, N; Kishioka, S; Nishida, S; Yamamoto, H, 1996)
" Seven days later, the animals were challenged with a dose of isoproterenol which would produce massive myocardial infarction and 50-60% mortality in non-treated animals."7.67Prolonged protective effects following propranolol withdrawal against isoproterenol-induced myocardial infarction in normotensive and hypertensive rats. ( Wexler, BC, 1985)
" Clonazepam, a commonly prescribed benzodiazepine, has been increasingly used as a countermeasure to cocaine side-effects, including sleep reduction and anxiety."3.96Combined cocaine and clonazepam administration induces REM sleep loss and anxiety-like withdrawal behaviors in rats. ( Andersen, ML; Dokkedal-Silva, V; Galduróz, JCF; Tufik, S, 2020)
"Chronic methamphetamine (MA) use can lead to increased symptoms of depression and anxiety during abstinence."3.91Stress-induced neural activation is altered during early withdrawal from chronic methamphetamine. ( Brooks, ML; Jacobskind, JS; Rosinger, ZJ; Zuloaga, DG, 2019)
" Rats were tested on social interaction, a measure of anxiety-like behavior, followed immediately by collection of amygdala tissue to measure CCL2 and TNFα or collection of the blood to measure corticosterone (CORT)."3.88Differential effects of single versus repeated minocycline administration-Lack of significant interaction with chronic alcohol history. ( Breese, GR; Harper, KM; Knapp, DJ; Park, MA, 2018)
" This study aims to investigate the potential effects of hydrogen-rich saline (HRS) administration on naloxone-precipitated withdrawal symptoms and morphine withdrawal-induced anxiety-like behaviors."3.85Hydrogen-rich saline attenuates anxiety-like behaviors in morphine-withdrawn mice. ( Cong, B; Gong, M; Guo, H; Hui, R; Ma, C; Shen, Q; Wang, J; Wen, D; Zhao, P, 2017)
"The aim of the present study was to investigate the effects of the selective agonists of the corticotropin-releasing factor (CRF) 2 receptor, urocortin 2 (UCN 2) and urocortin 3 (UCN 3), on the anxiety- and depression-like signs induced by acute nicotine withdrawal in mice."3.83Selective CRF2 receptor agonists ameliorate the anxiety- and depression-like state developed during chronic nicotine treatment and consequent acute withdrawal in mice. ( Bagosi, Z; Balangó, B; Bokor, P; Buzás, A; Csabafi, K; Jászberényi, M; Palotai, M; Pintér, D; Simon, B; Szabó, G, 2016)
" We analysed the time course of the global withdrawal score, the anxiety-like effects, monoamine concentrations, the brain-derived neurotrophic factor (BDNF) expression, the corticosterone plasmatic levels and [(3)H]epibatidine binding sites during NIC withdrawal precipitated by mecamylamine, a nicotinic receptor antagonist (MEC)."3.81Lack of GABAB receptors modifies behavioural and biochemical alterations induced by precipitated nicotine withdrawal. ( Antonelli, MC; Balerio, GN; Bettler, B; Machado, LM; Pedrón, VT; Varani, AP, 2015)
" The aggravation of alcohol withdrawal symptoms, such as anxiety, has been associated with increased levels of serum corticosterone and leptin."3.81N-acetylcysteine prevents behavioral and biochemical changes induced by alcohol cessation in rats. ( Clarimundo, V; Dalmaz, C; Elisabetsky, E; Gomez, R; Santos, CF; Schneider, R, 2015)
" Basally, HRs display lower anxiety-like behavior compared to LRs along with higher neuropeptide Y (NPY) mRNA in the amygdala and the hippocampus."3.77Effects of a selective Y2R antagonist, JNJ-31020028, on nicotine abstinence-related social anxiety-like behavior, neuropeptide Y and corticotropin releasing factor mRNA levels in the novelty-seeking phenotype. ( Aydin, C; Isgor, C; Oztan, O, 2011)
"Acute amphetamine administration activates monoaminergic pathways and increases systemic corticosterone, both of which influence anxiety states and adult dentate gyrus neurogenesis."3.76Withdrawal from chronic amphetamine produces persistent anxiety-like behavior but temporally-limited reductions in monoamines and neurogenesis in the adult rat dentate gyrus. ( Barr, JL; Forster, GL; Renner, KJ, 2010)
" Nifedipine, as a calcium channel blocker, can attenuate the development of morphine dependence; however, the role of the HPA axis in this effect has not been elucidated."3.74L-type calcium channel blockade attenuates morphine withdrawal: in vivo interaction between L-type calcium channels and corticosterone. ( Ahmadiani, A; Esmaeili-Mahani, S; Fathi, Y; Hosseinpanah, F; Motamedi, F, 2008)
" Eight hours after ethanol withdrawal, anxiety-like behaviour was tested in the elevated plus-maze, blood corticosterone levels were measured, and expression level of markers of neuronal activity and plasticity, c-fos and zif268, was assessed."3.73Previous experience of ethanol withdrawal increases withdrawal-induced c-fos expression in limbic areas, but not withdrawal-induced anxiety and prevents withdrawal-induced elevations in plasma corticosterone. ( Borlikova, GG; Le Merrer, J; Stephens, DN, 2006)
"Administration of amphetamine (AMPH) can induce symptoms of psychosis in humans and locomotor sensitization in rats; in contrast, withdrawal from a period of AMPH intake is most often associated with symptoms of human endogenous depression."3.72Amphetamine withdrawal does not produce a depressive-like state in rats as measured by three behavioral tests. ( Feldon, J; Murphy, CA; Nanz-Bahr, NI; Pezze, MA; Pryce, CR; Russig, H, 2003)
" We then measured the corticosterone and fever responses to LPS stimulation during the withdrawal period."3.72Suppressed fever and hypersensitivity responses in chicks prenatally exposed to opiates. ( Schrott, LM; Sparber, SB, 2004)
" The increase of plasma corticosterone (PCS: 52 and 52 microg/100 ml; control group, 18 and 15 microg/100 ml) and body weight loss (-6 and -9%; control group, 0 and -1%) were observed but PPE mRNA increase was not detected 1 and 2 h after naloxone in morphine treated rats."3.70Time course of morphine withdrawal and preproenkephalin gene expression in the periaqueductal gray of rats. ( Fukunaga, Y; Inoue, N; Kishioka, S; Miyamoto, M; Nishida, S; Yamamoto, H, 1998)
") was challenged 18 hr after infusion was stopped, and the withdrawal was evaluated by plasma corticosterone (PCS) increase, diarrhea and body weight loss."3.69Possible involvement of the total amount of morphine infused in the development of acute morphine dependence in rats. ( Fukunaga, Y; Inoue, N; Kishioka, S; Nishida, S; Yamamoto, H, 1996)
"Plasma morphine concentration and naloxone-precipitated withdrawal body weight loss and plasma corticosterone (PCS) increase were determined at 12, 18 and 24 hr after i."3.69No relation of plasma morphine level to the severity of naloxone-induced withdrawal in acute morphine-dependent rats. ( Fukunaga, Y; Inoue, N; Kishioka, S; Nishida, S; Yamamoto, H, 1995)
" The dose-dependent effects of naloxone on PCS and body weight were studied in male Sprague-Dawley rats rendered physically dependent on morphine by injecting increasing doses of 40-120 mg/kg/day, s."3.69Quantitative properties of plasma corticosterone elevation induced by naloxone-precipitated withdrawal in morphine-dependent rats. ( Fukunaga, Y; Kishioka, S; Nishida, S; Yamamoto, H, 1994)
" In naloxone-precipitated withdrawal, body weight loss and plasma corticosterone elevation were dose dependently inhibited by diltiazem injected 4 or 2 and 4 h before naloxone, respectively."3.69Diltiazem inhibits naloxone-precipitated and spontaneous morphine withdrawal in rats. ( Fukunaga, Y; Inoue, N; Kishioka, S; Nishida, S; Yamamoto, H, 1996)
" Seven days later, the animals were challenged with a dose of isoproterenol which would produce massive myocardial infarction and 50-60% mortality in non-treated animals."3.67Prolonged protective effects following propranolol withdrawal against isoproterenol-induced myocardial infarction in normotensive and hypertensive rats. ( Wexler, BC, 1985)
"The effects of the atypical antidepressant and serotonin antagonist mianserin on the expression of opiate withdrawal was examined using an acute and a chronic model of morphine dependence."3.67Mianserin attenuates naloxone-precipitated withdrawal signs in rats acutely or chronically dependent upon morphine. ( Neal, BS; Sparber, SB, 1986)
" In morphine-dependent animals, the incidence of abstinence signs and body weight loss during precipitated withdrawal did not appear to be significantly influenced by adrenalectomy or by corticosterone-pretreatment."3.65Morphine analgesia, tolerance and physical dependence in the adrenalectomized rat. ( Wei, E, 1973)
"Vigorous control of withdrawal and PTSD-related arousal symptoms should be sought during detoxification of patients with comorbid PTSD and substance use disorders."2.41Substance use disorders in patients with posttraumatic stress disorder: a review of the literature. ( Jacobsen, LK; Kosten, TR; Southwick, SM, 2001)
"Morphine has been shown to increase the expression of brain-derived neurotrophic factor (BDNF) in the brain."1.56Conditioned aversive memory associated with morphine withdrawal increases brain-derived neurotrophic factor in dentate gyrus and basolateral amygdala. ( Almela, P; Laorden, ML; Martínez-Laorden, E; Milanés, MV; Navarro-Zaragoza, J, 2020)
"Corticosterone was not elevated at withdrawal."1.51Withdrawal from Brief Repeated Alcohol Treatment in Adolescent and Adult Male and Female Rats. ( Chandra, U; Fleming, W; Francis, R; Jones, Q; Kuhn, C; Ocampo, G; Saini, A; Walker, D, 2019)
"Alcohol dependence is linked to dysregulation of the hypothalamic-pituitary-adrenal axis."1.46Abstinence from prolonged ethanol exposure affects plasma corticosterone, glucocorticoid receptor signaling and stress-related behaviors. ( Contet, C; Fannon, MJ; Guevara, J; Mandyam, CD; Nguyen, TB; Schmeichel, BE; Sidhu, H; Somkuwar, SS; Vendruscolo, LF; Zorrilla, EP, 2017)
"The key problem in treating cocaine addiction is the maintenance of a drug-free state as negative emotional symptoms during abstinence often trigger relapse."1.43Cocaine abstinence induces emotional impairment and brain region-specific upregulation of the oxytocin receptor binding. ( Bailey, A; Georgiou, P; Hourani, S; Kitchen, I; Zanos, P, 2016)
"Although no physical withdrawal symptoms or alterations in the plasma corticosterone levels were observed after 7 days of abstinence, mice exhibited increased anxiety-like and depressive-like behaviors and impaired sociability."1.40The oxytocin analogue carbetocin prevents emotional impairment and stress-induced reinstatement of opioid-seeking in morphine-abstinent mice. ( Bailey, A; Georgiou, P; Hourani, SM; Kitchen, I; Winsky-Sommerer, R; Wright, SR; Zanos, P, 2014)
"Corticosterone levels were significantly different at the end of the 15-min session, but not following the 2-h session."1.39Combinations of oxazepam and metyrapone attenuate cocaine and methamphetamine cue reactivity. ( Cornett, EM; Goeders, NE; Guerin, GF; Keller, CM, 2013)
"Corticosterone concentration was increased in brain and blood of mice during abstinence phase and pretreatment with nimodipine prevented the increase in brain and blood corticosterone concentration."1.38The effect of nimodipine on memory impairment during spontaneous morphine withdrawal in mice: Corticosterone interaction. ( Hajhashemi, V; Rabbani, M; Vaseghi, G, 2012)
"Morphine withdrawal was precipitated on day 8 by the injection of naloxone (2 mg/kg s."1.38Morphine withdrawal activates hypothalamic-pituitary-adrenal axis and heat shock protein 27 in the left ventricle: the role of extracellular signal-regulated kinase. ( Almela, P; Hurle, MA; Laorden, ML; Martínez-Laorden, E; Milanés, MV, 2012)
"The role of stress in drug addiction is well established."1.36Effects of corticotropin-releasing factor receptor-1 antagonists on the brain stress system responses to morphine withdrawal. ( Laorden, ML; Milanés, MV; Navarro-Zaragoza, J; Núñez, C, 2010)
"Cocaine addiction is known to impair immune system function, but the effects of repeated treatment with cocaine in a self-administration model, its withdrawal as well as reinstatement of cocaine-seeking behavior on cell-mediated immunity are not well known."1.35Immunosuppression induced by a conditioned stimulus associated with cocaine self-administration. ( Basta-Kaim, A; Budziszewska, B; Filip, M; Jaworska-Feil, L; Kubera, M; Lason, W; Leskiewicz, M; Machowska, A; Przegalinski, E; Regulska, M; Wydra, K, 2008)
"Both nimodipine treatments prevented the memory deficits when these were measured between 1 and 2 months after alcohol withdrawal."1.35Nimodipine prior to alcohol withdrawal prevents memory deficits during the abstinence phase. ( Brooks, SP; Croft, AP; Little, HJ; Norman, G; Shaw, SG, 2008)
"To induce opiate dependence, mice were treated with intermittent escalating morphine doses (20-100 mg/kg, i."1.35Disruption of the CRF(2) receptor pathway decreases the somatic expression of opiate withdrawal. ( Contarino, A; Ghozland, S; Ingallinesi, M; Koob, GF; Papaleo, F; Roberts, AJ, 2008)
"In contrast, the seizure prone DBA/2J inbred strain and the Withdrawal Seizure-Prone (WSP) selected line exhibited decreased sensitivity to ALLO's anticonvulsant effect during ethanol withdrawal, with no change in sensitivity in the Withdrawal Seizure-Resistant (WSR) line."1.35Decreased anticonvulsant efficacy of allopregnanolone during ethanol withdrawal in female Withdrawal Seizure-Prone vs. Withdrawal Seizure-Resistant mice. ( Beckley, EH; Crabbe, JC; Finn, DA; Fretwell, AM; Gililland, KR; Tanchuck, MA, 2008)
"Corticosterone levels were unchanged by alcohol consumption, but they were decreased by withdrawal in females."1.35Sexually dimorphic response of the hypothalamo-pituitary-adrenal axis to chronic alcohol consumption and withdrawal. ( Madeira, MD; Santos-Marques, MJ; Silva, SM, 2009)
"Corticosterone concentration was normalized 14 h after the last dose of morphine."1.35Increase in brain corticosterone concentration and recognition memory impairment following morphine withdrawal in mice. ( Hajhashemi, V; Mesripour, A; Rabbani, M, 2009)
"Handling-induced convulsions (HICs) were scored at baseline, and then over a 24 h period after EtOH or saline injection."1.34Sex differences in the effect of finasteride on acute ethanol withdrawal severity in C57BL/6J and DBA/2J mice. ( Finn, DA; Gorin-Meyer, RE; Long, SL; Tanchuck, MA; Wiren, KM; Yoneyama, N, 2007)
"Corticosterone levels were also significantly higher in restrained animals after EA stimulation."1.33Electroacupuncture attenuates morphine withdrawal signs and c-Fos expression in the central nucleus of the amygdala in freely moving rats. ( Liu, H; Liu, S; Yang, G; Zhao, W; Zhou, W, 2005)
" Previous studies revealed that chronic administration of the anxiolytic alprazolam reduced indices of CRF and CRF1 receptor function."1.32Spontaneous withdrawal from the triazolobenzodiazepine alprazolam increases cortical corticotropin-releasing factor mRNA expression. ( Nemeroff, CB; Owens, MJ; Skelton, KH, 2004)
" In the present work we have studied the effects of acute and chronic administration of the kappa agonist U-50,488H as well as the influence of U-50,488H withdrawal on the activity of hypothalamic NA and dopamine (DA) neurons and on the activity of hypothalamic-pituitary-adrenal (HPA) axis."1.31Effects of U-50,488H and U-50,488H withdrawal on catecholaminergic neurons of the rat hypothalamus. ( Laorden, ML; Milanés, MV, 2000)
"Corticosterone levels were positively correlated with fentanyl SA."1.30Sex differences in effects of predictable and unpredictable footshock on fentanyl self-administration in rats. ( Grunberg, NE; Klein, LC; Popke, EJ, 1997)
"These results suggest that withdrawal convulsions following acute ethanol, pentobarbital, and diazepam are sensitive to modulation by corticosterone and they support the hypothesis that stress may increase drug withdrawal severity."1.29Corticosterone increases severity of acute withdrawal from ethanol, pentobarbital, and diazepam in mice. ( Crabbe, JC; Keith, LD; Roberts, AJ, 1994)
"Diazepam has been shown to produce physical dependence based on observations of behavioral stimulation or, in our laboratory, by increases in plasma corticosterone (CS) during antagonist-precipitated withdrawal."1.28Effects of beta-carboline-ethyl ester on plasma corticosterone--a parallel with antagonist-precipitated diazepam withdrawal. ( Eisenberg, RM; Johnson, C, 1989)
"Ethanol withdrawal symptoms followed the removal of ethanol from the diet and circulating corticosterone concentrations were further increased."1.26Corticosterone concentrations in mice during ethanol drinking and withdrawal. ( Jafee, RC; Ritzmann, RF; Tabakoff, B, 1978)
"3."1.26Some responses of the immature fowl to the withdrawal of a stressor. ( Flack, IH; Freeman, BM; Manning, AC, 1980)

Research

Studies (154)

TimeframeStudies, this research(%)All Research%
pre-199028 (18.18)18.7374
1990's27 (17.53)18.2507
2000's46 (29.87)29.6817
2010's47 (30.52)24.3611
2020's6 (3.90)2.80

Authors

AuthorsStudies
Vassoler, FM1
Isgate, SB1
Budge, KE1
Byrnes, EM1
Islas-Preciado, D1
Ugalde-Fuentes, G1
Sollozo-Dupont, I1
González Trujano, ME1
Cervantes-Anaya, N1
Estrada-Camarena, E1
López-Rubalcava, C1
Cruz, B1
Castañeda, K1
Aranda, M1
Hinojosa, CA1
Castro-Gutierrez, R1
Flores, RJ1
Spencer, CT1
Vozella, V1
Roberto, M1
Gadad, BS1
Roychowdhury, S1
O'Dell, LE1
Bray, B2
Clement, KA1
Bachmeier, D1
Weber, MA1
Forster, GL3
Dokkedal-Silva, V1
Galduróz, JCF1
Tufik, S1
Andersen, ML1
Wen, D1
Zhao, P1
Hui, R1
Wang, J1
Shen, Q1
Gong, M1
Guo, H1
Cong, B1
Ma, C1
Somkuwar, SS1
Vendruscolo, LF1
Fannon, MJ1
Schmeichel, BE1
Nguyen, TB1
Guevara, J1
Sidhu, H1
Contet, C1
Zorrilla, EP1
Mandyam, CD1
Domi, E1
Barbier, E1
Augier, E1
Augier, G1
Gehlert, D1
Barchiesi, R1
Thorsell, A1
Holm, L1
Heilig, M1
Harper, KM1
Knapp, DJ2
Park, MA1
Breese, GR2
Fleming, W1
Jones, Q1
Chandra, U1
Saini, A1
Walker, D1
Francis, R1
Ocampo, G1
Kuhn, C1
Jacobskind, JS1
Rosinger, ZJ1
Brooks, ML1
Zuloaga, DG1
Martínez-Laorden, E2
Navarro-Zaragoza, J3
Milanés, MV14
Laorden, ML12
Almela, P3
Sharrett-Field, L1
Butler, TR2
Berry, JN2
Reynolds, AR2
Prendergast, MA4
Zhou, Y7
Leri, F2
Ho, A4
Kreek, MJ7
Sharrett-Field, LJ1
Pauly, JR1
Keller, CM1
Cornett, EM1
Guerin, GF1
Goeders, NE1
Hamilton, KL1
Harris, AC1
Gewirtz, JC1
Zanos, P3
Georgiou, P3
Wright, SR1
Hourani, SM1
Kitchen, I3
Winsky-Sommerer, R1
Bailey, A3
Ueno, K1
Kiguchi, N1
Kobayashi, Y1
Saika, F1
Wakida, N1
Yamamoto, C1
Maeda, T1
Ozaki, M1
Kishioka, S6
Abe, K1
Kobayashi, K1
Yoshino, S1
Taguchi, K1
Nojima, H1
Doremus-Fitzwater, TL1
Buck, HM2
Bordner, K1
Richey, L1
Jones, ME1
Deak, T2
Tanchuck-Nipper, MA1
Ford, MM1
Hertzberg, A1
Beadles-Bohling, A1
Cozzoli, DK1
Finn, DA5
Zhao, Z1
Lee, BH1
Lin, F1
Guo, Y1
Wu, Y1
In, S1
Park, SM1
Chan Kim, S1
Yang, CH1
Zhao, R1
Varani, AP1
Pedrón, VT1
Machado, LM1
Antonelli, MC1
Bettler, B1
Balerio, GN1
Wilhelm, CJ1
Hashimoto, JG1
Roberts, ML1
Bloom, SH1
Beard, DK1
Wiren, KM2
Schneider, R1
Santos, CF1
Clarimundo, V1
Dalmaz, C1
Elisabetsky, E1
Gomez, R1
García-Carmona, JA3
Baroja-Mazo, A1
Caffino, L1
Giannotti, G1
Malpighi, C1
Racagni, G1
Fumagalli, F1
Saunders, MA1
Brewton, HW1
Winchester, SR1
Elgumati, IS1
Dominguez, G1
Belzung, C1
Pierard, C1
David, V1
Henkous, N1
Decorte, L1
Mons, N1
Beracochea, D1
Hourani, S2
Scholl, JL1
Tu, W1
Watt, MJ1
Renner, KJ2
Bagosi, Z1
Palotai, M1
Simon, B1
Bokor, P1
Buzás, A1
Balangó, B1
Pintér, D1
Jászberényi, M1
Csabafi, K1
Szabó, G1
Kato, H1
Tsuji, M1
Miyagawa, K1
Takeda, K1
Takeda, H1
Ligeiro de Oliveira, AP1
Lazzarini, R1
Cavriani, G1
Quinteiro-Filho, WM1
Tavares de Lima, W1
Palermo-Neto, J1
Kubera, M1
Filip, M1
Budziszewska, B2
Basta-Kaim, A1
Wydra, K1
Leskiewicz, M1
Regulska, M1
Jaworska-Feil, L2
Przegalinski, E1
Machowska, A1
Lason, W2
Brooks, SP1
Croft, AP1
Norman, G1
Shaw, SG1
Little, HJ2
Alves, CJ1
Magalhães, A1
Summavielle, T1
Melo, P1
De Sousa, L1
Tavares, MA1
Monteiro, PR1
Hodgson, SR1
Hofford, RS1
Norris, CJ1
Eitan, S1
Núñez, C2
Földes, A1
Pérez-Flores, D1
García-Borrón, JC1
Kovács, KJ1
Rabbani, M2
Hajhashemi, V2
Mesripour, A1
Strong, MN1
Kaufman, KR1
Crabbe, JC5
Silva, SM2
Santos-Marques, MJ1
Madeira, MD3
Barr, JL1
Maiya, R1
Norris, EH1
Strickland, S1
Goeldner, C1
Lutz, PE1
Darcq, E1
Halter, T1
Clesse, D1
Ouagazzal, AM1
Kieffer, BL1
Whitman, BA1
Wills, TA1
Angel, RA1
Overstreet, DH1
Criswell, HE1
Ming, Z1
Aydin, C1
Oztan, O1
Isgor, C1
Hueston, CM1
Bishop, C1
Kupferschmidt, DA1
Newman, AE1
Boonstra, R1
Erb, S1
Thiel, KJ1
Painter, MR1
Pentkowski, NS1
Mitroi, D1
Crawford, CA1
Neisewander, JL1
Ingallinesi, M2
Rouibi, K1
Le Moine, C1
Papaleo, F3
Contarino, A3
Kozlov, AP1
Nizhnikov, ME1
Varlinskaya, EI1
Spear, NE1
Hurle, MA1
Skwara, AJ1
Karwoski, TE1
Czambel, RK1
Rubin, RT1
Rhodes, ME1
García-Fuster, MJ1
Flagel, SB1
Mahmood, ST1
Watson, SJ1
Akil, H1
Vaseghi, G1
Mora, L1
Hidalgo, J1
Schrott, LM2
Baumgart, MI1
Zhang, X1
Sparber, SB3
Cerezo, M1
Spangler, R2
Schlussman, SD1
Russig, H1
Pezze, MA1
Nanz-Bahr, NI1
Pryce, CR1
Feldon, J1
Murphy, CA1
Oliva, JM1
Ortiz, S1
Palomo, T1
Manzanares, J1
Bull, EJ1
Hutson, PH1
Fone, KC1
Avila, AH2
Morgan, CA1
Bayer, BM2
Semba, J1
Wakuta, M1
Maeda, J1
Suhara, T1
Alonzo, NC1
Lelas, S1
Wong, H1
Li, YW1
Heman, KL1
Ward, KA1
Zeller, KL1
Sieracki, KK1
Polino, JL1
Godonis, HE1
Ren, SX1
Yan, XX1
Arneric, SP1
Robertson, DW1
Hartig, PR1
Grossman, S1
Trainor, GL1
Taub, RA1
Zaczek, R1
Gilligan, PJ1
McElroy, JF1
González, S1
Fernández-Ruiz, J1
Di Marzo, V1
Hernández, M1
Arévalo, C1
Nicanor, C1
Cascio, MG1
Ambrosio, E1
Ramos, JA1
Baumann, MH2
Milchanowski, AB1
Rothman, RB2
Skelton, KH1
Nemeroff, CB1
Owens, MJ1
Liu, S1
Zhou, W1
Liu, H1
Yang, G1
Zhao, W1
Mulholland, PJ1
Self, RL1
Harris, BR1
Littleton, JM1
Kelschenbach, J1
Barke, RA1
Roy, S1
Borlikova, GG1
Le Merrer, J1
Stephens, DN1
Alele, PE1
Devaud, LL1
Carrasco, GA1
Van de Kar, LD1
Sullivan, NR1
Landry, M1
Garcia, F1
Muma, NA1
Battaglia, G1
Bendor, J1
Hofmann, L1
Randesi, M1
Mantsch, JR1
Taves, S1
Khan, T1
Katz, ES1
Sajan, T1
Tang, LC1
Cullinan, WE1
Ziegler, DR1
Kitchener, P1
Gorin-Meyer, RE1
Tanchuck, MA2
Long, SL1
Yoneyama, N1
Cummins, E1
Hoeschele, M1
Gililland, KR2
Beckley, EH1
Fretwell, AM1
Esmaeili-Mahani, S1
Fathi, Y1
Motamedi, F1
Hosseinpanah, F1
Ahmadiani, A1
Ghozland, S1
Roberts, AJ3
Koob, GF2
Healey, JC1
Winder, DG1
Kash, TL1
Freeman, BM1
Manning, AC1
Flack, IH1
Keith, LD3
Robertson, LM1
Young, ER1
Guaza, C1
Borrell, S1
Eisenberg, RM5
Badawy, AA2
Punjani, NF2
Evans, CM1
Evans, M2
Becketts, KM1
Nishida, S5
Fukunaga, Y5
Yamamoto, H6
Shaham, Y1
Gonzalvez, ML1
Martinez-Piñero, MG2
Marín, MT1
Vargas, ML3
Kleven, M1
Ybema, C1
Carilla, E1
Hamon, M1
Koek, W1
Inoue, N4
Alcaraz, C1
Andrade, JP1
Lieberman, AR1
Sousa, N1
Almeida, OF1
Paula-Barbosa, MM1
Rodríguez de Fonseca, F1
Carrera, MR1
Navarro, M1
Weiss, F1
Klein, LC2
Popke, EJ1
Grunberg, NE1
Abdel Raheem, K1
Ismael, N1
Saad, A1
el-Sayad, S1
Patacchioli, FR1
Pontieri, FE1
Orzi, F1
Di Grezia, R1
Angelucci, L1
Prasad, BM1
Ulibarri, C1
Sorg, BA1
Chapleur-Château, M1
Burlet, A1
Miyamoto, M1
Timpl, P1
Spanagel, R1
Sillaber, I1
Kresse, A1
Reul, JM1
Stalla, GK1
Blanquet, V1
Steckler, T1
Holsboer, F1
Wurst, W1
Rabadán, JV1
Stock, H1
Ford, K1
Biscardi, R1
Wilson, MA1
Fuertes, G1
Rasmussen, K1
Calligaro, DO1
Czachura, JF1
Dreshfield-Ahmad, LJ1
Evans, DC1
Hemrick-Luecke, SK1
Kallman, MJ1
Kendrick, WT1
Leander, JD1
Nelson, DL1
Overshiner, CD1
Wainscott, DB1
Wolff, MC1
Wong, DT1
Branchek, TA1
Zgombick, JM1
Xu, YC1
Jacobsen, LK1
Southwick, SM1
Kosten, TR1
Houshyar, H1
Galigniana, MD1
Pratt, WB1
Woods, JH1
Tabakoff, B1
Jafee, RC1
Ritzmann, RF1
Benwell, ME1
Balfour, DJ2
Pohorecky, LA1
Kakihana, R1
Gibson, A2
Pollock, D2
Katovich, MJ1
Pitman, D1
Schechtman, O1
Maldonado, R2
Fournié-Zaluski, MC2
Roques, BP2
Ignar, DM1
Kuhn, CM1
Copland, AM1
Johnson, C1
Andersson, K1
Fuxe, K1
Eneroth, P1
Jansson, A1
Härfstrand, A1
Daugé, V1
Callebert, J1
Villette, JM1
Feger, J1
Neal, BS1
Gadek, A1
Cetera, B1
Bugajski, J1
Wexler, BC1
Mikita, S2
Sable-Amplis, R1
Agid, R1
Abadie, D1
Sze, PY1
Yanai, J1
Ginsburg, BE1
Yano, I1
Masuda, Y1
Murano, T1
Wei, E1
Norton, PR1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of N-acetylcysteine (NAC) on Treatment of Alcohol and Cocaine Use Disorders: A Double-Blind Randomized Controlled Trial.[NCT03018236]Phase 4100 participants (Anticipated)Interventional2017-01-31Recruiting
A Pilot Study of N-acetylcysteine for Alcohol Use Disorder[NCT04964843]Phase 20 participants (Actual)Interventional2023-04-30Withdrawn (stopped due to Null results were posted from a neurometabolite study and a recent trial for AUD. Study may resume if more positive data emerge.)
PT150 (Formerly ORG34517) as a Potential Treatment for Alcohol Dependence-Alcohol Interaction Study[NCT03548714]Phase 110 participants (Actual)Interventional2018-09-01Completed
The Efficiency of Eye Movement Desensitization and Reprocessing (EMDR) for the Treatment of Substance Use Disorders: A Randomized Controlled Trial[NCT03114423]60 participants (Anticipated)Interventional2017-04-07Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for corticosterone and Drug Withdrawal Symptoms

ArticleYear
Substance use disorders in patients with posttraumatic stress disorder: a review of the literature.
    The American journal of psychiatry, 2001, Volume: 158, Issue:8

    Topics: Adult; Animals; Arousal; Comorbidity; Corticosterone; Corticotropin-Releasing Hormone; Diagnosis, Du

2001

Other Studies

153 other studies available for corticosterone and Drug Withdrawal Symptoms

ArticleYear
HPA axis dysfunction during morphine withdrawal in offspring of female rats exposed to opioids preconception.
    Neuroscience letters, 2022, 03-16, Volume: 773

    Topics: Analgesics, Opioid; Animals; Corticosterone; Corticotropin-Releasing Hormone; Female; Hypothalamo-Hy

2022
Anxiety-like Behavior and GABAAR/BDZ Binding Site Response to Progesterone Withdrawal in a Stress-Vulnerable Strain, the Wistar Kyoto Rats.
    International journal of molecular sciences, 2022, Jun-30, Volume: 23, Issue:13

    Topics: Animals; Anxiety; Behavior, Animal; Binding Sites; Corticosterone; Diazepam; Female; Flunitrazepam;

2022
Alcohol self-administration and nicotine withdrawal alter biomarkers of stress and inflammation and prefrontal cortex changes in Gβ subunits.
    The American journal of drug and alcohol abuse, 2023, 05-04, Volume: 49, Issue:3

    Topics: Animals; Corticosterone; Ethanol; Leptin; Male; Nicotine; Prefrontal Cortex; Rats; Rats, Wistar; Sub

2023
Corticosterone in the ventral hippocampus differentially alters accumbal dopamine output in drug-naïve and amphetamine-withdrawn rats.
    Neuropharmacology, 2020, 03-15, Volume: 165

    Topics: Amphetamine; Animals; Central Nervous System Stimulants; Corticosterone; Dopamine; Hippocampus; Male

2020
Combined cocaine and clonazepam administration induces REM sleep loss and anxiety-like withdrawal behaviors in rats.
    Pharmacology, biochemistry, and behavior, 2020, Volume: 197

    Topics: Animals; Anxiety; Behavior, Animal; Clonazepam; Cocaine; Corticosterone; Exploratory Behavior; Male;

2020
Hydrogen-rich saline attenuates anxiety-like behaviors in morphine-withdrawn mice.
    Neuropharmacology, 2017, 05-15, Volume: 118

    Topics: Adaptation, Ocular; Animals; Anti-Anxiety Agents; Anxiety; Corticosterone; Disease Models, Animal; D

2017
Abstinence from prolonged ethanol exposure affects plasma corticosterone, glucocorticoid receptor signaling and stress-related behaviors.
    Psychoneuroendocrinology, 2017, Volume: 84

    Topics: Alcohol Drinking; Alcoholism; Animals; Corticosterone; Disease Models, Animal; Ethanol; Hypothalamo-

2017
Preclinical evaluation of the kappa-opioid receptor antagonist CERC-501 as a candidate therapeutic for alcohol use disorders.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2018, Volume: 43, Issue:9

    Topics: Alcohol Deterrents; Alcoholism; Animals; Anxiety; Benzamides; Central Nervous System Depressants; Co

2018
Differential effects of single versus repeated minocycline administration-Lack of significant interaction with chronic alcohol history.
    Pharmacology, biochemistry, and behavior, 2018, Volume: 168

    Topics: Alcoholism; Amygdala; Animals; Anti-Bacterial Agents; Anxiety; Chemokine CCL2; Corticosterone; Drug

2018
Withdrawal from Brief Repeated Alcohol Treatment in Adolescent and Adult Male and Female Rats.
    Alcoholism, clinical and experimental research, 2019, Volume: 43, Issue:2

    Topics: Aging; Animals; Behavior, Animal; Blood Alcohol Content; Corticosterone; Drug Tolerance; Ethanol; Fe

2019
Stress-induced neural activation is altered during early withdrawal from chronic methamphetamine.
    Behavioural brain research, 2019, 07-02, Volume: 366

    Topics: Animals; Anxiety; Brain; CA3 Region, Hippocampal; Central Nervous System Stimulants; Corticosterone;

2019
Conditioned aversive memory associated with morphine withdrawal increases brain-derived neurotrophic factor in dentate gyrus and basolateral amygdala.
    Addiction biology, 2020, Volume: 25, Issue:4

    Topics: Affect; Analgesics, Opioid; Animals; Basolateral Nuclear Complex; Brain-Derived Neurotrophic Factor;

2020
Mifepristone pretreatment reduces ethanol withdrawal severity in vivo.
    Alcoholism, clinical and experimental research, 2013, Volume: 37, Issue:8

    Topics: Alcoholism; Animals; Body Weight; Corticosterone; Drug Evaluation, Preclinical; Eating; Ethanol; Hor

2013
Suppression of hypothalamic-pituitary-adrenal axis by acute heroin challenge in rats during acute and chronic withdrawal from chronic heroin administration.
    Neurochemical research, 2013, Volume: 38, Issue:9

    Topics: Acute Disease; Adrenocorticotropic Hormone; Animals; Chronic Disease; Corticosterone; Heroin; Hypoth

2013
Long-term ethanol and corticosterone co-exposure sensitize the hippocampal ca1 region pyramidal cells to insult during ethanol withdrawal in an NMDA GluN2B subunit-dependent manner.
    Alcoholism, clinical and experimental research, 2013, Volume: 37, Issue:12

    Topics: Animals; CA1 Region, Hippocampal; Corticosterone; Ethanol; Female; Male; Organ Culture Techniques; P

2013
Combinations of oxazepam and metyrapone attenuate cocaine and methamphetamine cue reactivity.
    Drug and alcohol dependence, 2013, Dec-01, Volume: 133, Issue:2

    Topics: Amphetamine-Related Disorders; Analysis of Variance; Animals; Central Nervous System Stimulants; Coc

2013
Affective and neuroendocrine effects of withdrawal from chronic, long-acting opiate administration.
    Brain research, 2013, Nov-13, Volume: 1538

    Topics: Affect; Animals; Corticosterone; Male; Methadyl Acetate; Naloxone; Narcotic Antagonists; Narcotics;

2013
The oxytocin analogue carbetocin prevents emotional impairment and stress-induced reinstatement of opioid-seeking in morphine-abstinent mice.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2014, Volume: 39, Issue:4

    Topics: Affective Symptoms; Analysis of Variance; Animals; Brain; Corticosterone; Dose-Response Relationship

2014
Possible involvement of endogenous opioid system located downstream of α7 nicotinic acetylcholine receptor in mice with physical dependence on nicotine.
    Journal of pharmacological sciences, 2014, Volume: 124, Issue:1

    Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Biomarkers; Corticosterone; Dose-Respon

2014
Withdrawal of repeated morphine enhances histamine-induced scratching responses in mice.
    Drug and chemical toxicology, 2015, Volume: 38, Issue:2

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Corticosterone; Dose-Response Relationship, Drug; His

2015
Intoxication- and withdrawal-dependent expression of central and peripheral cytokines following initial ethanol exposure.
    Alcoholism, clinical and experimental research, 2014, Volume: 38, Issue:8

    Topics: Age Factors; Alcoholic Intoxication; Animals; Brain; Corticosterone; Drug Tolerance; Ethanol; Interl

2014
Sex Differences in Ethanol's Anxiolytic Effect and Chronic Ethanol Withdrawal Severity in Mice with a Null Mutation of the 5α-Reductase Type 1 Gene.
    Behavior genetics, 2015, Volume: 45, Issue:3

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Alcohol Drinking; Animals; Anti-Anxiety Agents; Behavior, Ani

2015
Effects of acupuncture at Zu-San-Li (ST36) on the activity of the hypothalamic--pituitary--adrenal axis during ethanol withdrawal in rats.
    Journal of acupuncture and meridian studies, 2014, Volume: 7, Issue:5

    Topics: Acupuncture Points; Acupuncture Therapy; Adrenocorticotropic Hormone; Animals; Corticosterone; Corti

2014
Lack of GABAB receptors modifies behavioural and biochemical alterations induced by precipitated nicotine withdrawal.
    Neuropharmacology, 2015, Volume: 90

    Topics: Animals; Anxiety; Brain; Brain-Derived Neurotrophic Factor; Corticosterone; Disease Models, Animal;

2015
Persistent increases in rat hypothalamic POMC gene expression following chronic withdrawal from chronic "binge" pattern escalating-dose, but not steady-dose, cocaine.
    Neuroscience, 2015, Mar-19, Volume: 289

    Topics: Amygdala; Animals; Body Weight; Cocaine; Cocaine-Related Disorders; Corticosterone; Dopamine Uptake

2015
Females uniquely vulnerable to alcohol-induced neurotoxicity show altered glucocorticoid signaling.
    Brain research, 2015, Mar-19, Volume: 1601

    Topics: Alcoholism; Animals; Cell Death; Corticosterone; Ethanol; Female; Gene Expression; Glucocorticoids;

2015
N-acetylcysteine prevents behavioral and biochemical changes induced by alcohol cessation in rats.
    Alcohol (Fayetteville, N.Y.), 2015, Volume: 49, Issue:3

    Topics: Acetylcysteine; Animals; Anxiety; Behavior, Animal; Central Nervous System Depressants; Corticostero

2015
N-acetylcysteine prevents behavioral and biochemical changes induced by alcohol cessation in rats.
    Alcohol (Fayetteville, N.Y.), 2015, Volume: 49, Issue:3

    Topics: Acetylcysteine; Animals; Anxiety; Behavior, Animal; Central Nervous System Depressants; Corticostero

2015
N-acetylcysteine prevents behavioral and biochemical changes induced by alcohol cessation in rats.
    Alcohol (Fayetteville, N.Y.), 2015, Volume: 49, Issue:3

    Topics: Acetylcysteine; Animals; Anxiety; Behavior, Animal; Central Nervous System Depressants; Corticostero

2015
N-acetylcysteine prevents behavioral and biochemical changes induced by alcohol cessation in rats.
    Alcohol (Fayetteville, N.Y.), 2015, Volume: 49, Issue:3

    Topics: Acetylcysteine; Animals; Anxiety; Behavior, Animal; Central Nervous System Depressants; Corticostero

2015
Sex differences between CRF1 receptor deficient mice following naloxone-precipitated morphine withdrawal in a conditioned place aversion paradigm: implication of HPA axis.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Adrenocorticotropic Hormone; Animals; Body Weight; Corticosterone; Female; Genotype; Hypothalamo-Hyp

2015
Short-term withdrawal from developmental exposure to cocaine activates the glucocorticoid receptor and alters spine dynamics.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2015, Volume: 25, Issue:10

    Topics: Animals; Cocaine; Corticosterone; Dendritic Spines; Disease Models, Animal; Dopamine Uptake Inhibito

2015
Acute oral administration of the novel, competitive and selective glucocorticoid receptor antagonist ORG 34517 reduces the severity of ethanol withdrawal and related hypothalamic-pituitary-adrenal axis activation.
    Drug and alcohol dependence, 2015, Sep-01, Volume: 154

    Topics: Administration, Oral; Alcohol Drinking; Alcoholism; Animals; Benzodioxoles; Corticosterone; Ethanol;

2015
Alcohol withdrawal induces long-lasting spatial working memory impairments: relationship with changes in corticosterone response in the prefrontal cortex.
    Addiction biology, 2017, Volume: 22, Issue:4

    Topics: Alcoholism; Animals; Behavior, Animal; Corticosterone; Disease Models, Animal; Hippocampus; Male; Me

2017
Methamphetamine abstinence induces changes in μ-opioid receptor, oxytocin and CRF systems: Association with an anxiogenic phenotype.
    Neuropharmacology, 2016, Volume: 105

    Topics: Amphetamine-Related Disorders; Amygdala; Animals; Anxiety; Central Nervous System Stimulants; Corpus

2016
Amphetamine withdrawal differentially affects hippocampal and peripheral corticosterone levels in response to stress.
    Brain research, 2016, 08-01, Volume: 1644

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Amphetamine; Animals; Carbohydrate Dehydrogenases; Cent

2016
Cocaine abstinence induces emotional impairment and brain region-specific upregulation of the oxytocin receptor binding.
    The European journal of neuroscience, 2016, Volume: 44, Issue:7

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Corticosterone; Emotions; Hypothalamo

2016
Selective CRF2 receptor agonists ameliorate the anxiety- and depression-like state developed during chronic nicotine treatment and consequent acute withdrawal in mice.
    Brain research, 2016, 12-01, Volume: 1652

    Topics: Animals; Anxiety; Corticosterone; Depression; Disease Models, Animal; Drug Evaluation, Preclinical;

2016
Ethanol Withdrawal-Induced Impaired Recognition Is Reversed by Chronic Exposure to Stress and the Acute Administration of Corticosterone in Mice.
    Biological & pharmaceutical bulletin, 2016, Volume: 39, Issue:10

    Topics: Alcoholism; Animals; Corticosterone; Ethanol; Male; Mice, Inbred ICR; Recognition, Psychology; Stres

2016
Effects of single or repeated amphetamine treatment and withdrawal on lung allergic inflammation in rats.
    International immunopharmacology, 2008, Volume: 8, Issue:9

    Topics: Alveolitis, Extrinsic Allergic; Amphetamine; Animals; Antipsychotic Agents; Bone Marrow Cells; Bronc

2008
Immunosuppression induced by a conditioned stimulus associated with cocaine self-administration.
    Journal of pharmacological sciences, 2008, Volume: 107, Issue:4

    Topics: Animals; Cell Proliferation; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corticostero

2008
Nimodipine prior to alcohol withdrawal prevents memory deficits during the abstinence phase.
    Neuroscience, 2008, Nov-19, Volume: 157, Issue:2

    Topics: Alcohol-Induced Disorders; Alcohols; Analysis of Variance; Animals; Body Weight; Brain; Calcium Chan

2008
Hormonal, neurochemical, and behavioral response to a forced swim test in adolescent rats throughout cocaine withdrawal.
    Annals of the New York Academy of Sciences, 2008, Volume: 1139

    Topics: Animals; Behavior, Animal; Cocaine; Corticosterone; Dopamine; Female; Humans; Male; Motor Activity;

2008
Increased elevated plus maze open-arm time in mice during naloxone-precipitated morphine withdrawal.
    Behavioural pharmacology, 2008, Volume: 19, Issue:8

    Topics: Animals; Behavior, Animal; Corticosterone; Dose-Response Relationship, Drug; Male; Maze Learning; Mi

2008
Elevated glucocorticoid levels are responsible for induction of tyrosine hydroxylase mRNA expression, phosphorylation, and enzyme activity in the nucleus of the solitary tract during morphine withdrawal.
    Endocrinology, 2009, Volume: 150, Issue:7

    Topics: Adrenalectomy; Adrenocorticotropic Hormone; Animals; Corticosterone; Hydrocortisone; Male; Morphine;

2009
Increase in brain corticosterone concentration and recognition memory impairment following morphine withdrawal in mice.
    Stress (Amsterdam, Netherlands), 2009, Volume: 12, Issue:5

    Topics: Animals; Brain; Corticosterone; Male; Memory Disorders; Memory, Short-Term; Mice; Morphine; Naloxone

2009
Sex differences in acute ethanol withdrawal severity after adrenalectomy and gonadectomy in Withdrawal Seizure-Prone and Withdrawal Seizure-Resistant mice.
    Alcohol (Fayetteville, N.Y.), 2009, Volume: 43, Issue:5

    Topics: Adrenal Glands; Adrenalectomy; Alcohol Withdrawal Seizures; Animals; Anticonvulsants; Corticosterone

2009
Sexually dimorphic response of the hypothalamo-pituitary-adrenal axis to chronic alcohol consumption and withdrawal.
    Brain research, 2009, Dec-15, Volume: 1303

    Topics: Alcohol-Induced Disorders, Nervous System; Alcoholism; Animals; Cell Death; Chronic Disease; Cortico

2009
Effects of corticotropin-releasing factor receptor-1 antagonists on the brain stress system responses to morphine withdrawal.
    Molecular pharmacology, 2010, Volume: 77, Issue:5

    Topics: Adrenocorticotropic Hormone; Animals; Brain; Brain Stem; Corticosterone; Iodine Radioisotopes; Male;

2010
Withdrawal from chronic amphetamine produces persistent anxiety-like behavior but temporally-limited reductions in monoamines and neurogenesis in the adult rat dentate gyrus.
    Neuropharmacology, 2010, Volume: 59, Issue:6

    Topics: Amphetamine; Analysis of Variance; Animals; Anxiety; Cell Count; Cell Death; Corticosterone; Dentate

2010
Involvement of tissue plasminogen activator in stress responsivity during acute cocaine withdrawal in mice.
    Stress (Amsterdam, Netherlands), 2010, Volume: 13, Issue:6

    Topics: Amygdala; Animals; Cocaine; Corticosterone; Corticotropin-Releasing Hormone; Hippocampus; Hypothalam

2010
Impaired emotional-like behavior and serotonergic function during protracted abstinence from chronic morphine.
    Biological psychiatry, 2011, Feb-01, Volume: 69, Issue:3

    Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Disease Models, Animal; Drug Evaluation, Precl

2011
Cytokine involvement in stress may depend on corticotrophin releasing factor to sensitize ethanol withdrawal anxiety.
    Brain, behavior, and immunity, 2011, Volume: 25 Suppl 1

    Topics: Adaptation, Psychological; Alcohols; Amygdala; Analysis of Variance; Animals; Anxiety; Corticosteron

2011
Effects of a selective Y2R antagonist, JNJ-31020028, on nicotine abstinence-related social anxiety-like behavior, neuropeptide Y and corticotropin releasing factor mRNA levels in the novelty-seeking phenotype.
    Behavioural brain research, 2011, Sep-23, Volume: 222, Issue:2

    Topics: Amygdala; Animals; Anxiety; Benzamides; CA3 Region, Hippocampal; Corticosterone; Corticotropin-Relea

2011
Enhancement of the hypothalamic-pituitary-adrenal axis but not cytokine responses to stress challenges imposed during withdrawal from acute alcohol exposure in Sprague-Dawley rats.
    Psychopharmacology, 2011, Volume: 218, Issue:1

    Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Cytokines; Ethanol; Gene Expression Regulation

2011
Antagonism of cannabinoid 1 receptors reverses the anxiety-like behavior induced by central injections of corticotropin-releasing factor and cocaine withdrawal.
    Neuroscience, 2012, Mar-01, Volume: 204

    Topics: Animals; Anxiety; Behavior, Animal; Cocaine; Corticosterone; Corticotropin-Releasing Hormone; Dopami

2012
Environmental enrichment counters cocaine abstinence-induced stress and brain reactivity to cocaine cues but fails to prevent the incubation effect.
    Addiction biology, 2012, Volume: 17, Issue:2

    Topics: Animals; Brain-Derived Neurotrophic Factor; Cocaine; Cocaine-Related Disorders; Conditioning, Operan

2012
CRF2 receptor-deficiency eliminates opiate withdrawal distress without impairing stress coping.
    Molecular psychiatry, 2012, Volume: 17, Issue:12

    Topics: Adaptation, Psychological; Animals; Behavior, Addictive; Brain; Corticosterone; Corticotropin-Releas

2012
The role of social isolation in ethanol effects on the preweanling rat.
    Behavioural brain research, 2012, Feb-01, Volume: 227, Issue:1

    Topics: Analysis of Variance; Animals; Animals, Newborn; Central Nervous System Depressants; Corticosterone;

2012
Effects of chronic alcohol consumption and withdrawal on the response of the male and female hypothalamic-pituitary-adrenal axis to acute immune stress.
    Brain research, 2012, Mar-20, Volume: 1444

    Topics: Alcohol Drinking; Animals; Corticosterone; Corticotropin-Releasing Hormone; Disease Models, Animal;

2012
Morphine withdrawal activates hypothalamic-pituitary-adrenal axis and heat shock protein 27 in the left ventricle: the role of extracellular signal-regulated kinase.
    The Journal of pharmacology and experimental therapeutics, 2012, Volume: 342, Issue:3

    Topics: Adrenergic beta-Antagonists; Adrenocorticotropic Hormone; Aminoacetonitrile; Animals; Catechol O-Met

2012
Influence of environmental enrichment on hypothalamic-pituitary-adrenal (HPA) responses to single-dose nicotine, continuous nicotine by osmotic mini-pumps, and nicotine withdrawal by mecamylamine in male and female rats.
    Behavioural brain research, 2012, Sep-01, Volume: 234, Issue:1

    Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Female; Hypothalamus; Male; Mecamylamine; Nico

2012
Cocaine withdrawal causes delayed dysregulation of stress genes in the hippocampus.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: Animals; Cocaine; Corticosterone; Gene Expression Regulation; Hippocampus; In Situ Hybridization; Ma

2012
The effect of nimodipine on memory impairment during spontaneous morphine withdrawal in mice: Corticosterone interaction.
    European journal of pharmacology, 2012, Nov-15, Volume: 695, Issue:1-3

    Topics: Animals; Brain; Calcium Channel Blockers; Corticosterone; Male; Memory Disorders; Mice; Morphine; Ni

2012
Role of corticotropin-releasing factor (CRF) receptor-1 on the catecholaminergic response to morphine withdrawal in the nucleus accumbens (NAc).
    PloS one, 2012, Volume: 7, Issue:10

    Topics: Animals; Corticosterone; Dopamine; Male; Morphine; Morphine Dependence; Naloxone; Neurons; Norepinep

2012
Prenatal opiate withdrawal activates the chick embryo hypothalamic pituitary-adrenal axis and dilates vitelline blood vessels via serotonin(2) receptors.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Chick Embryo; Corticosterone; Disease Models, Animal; Hypothal

2002
Inhibition of protein kinase C but not protein kinase A attenuates morphine withdrawal excitation of rat hypothalamus-pituitary-adrenal axis.
    European journal of pharmacology, 2002, Sep-27, Volume: 452, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Analgesics, Opioid; Animals; Blood-Brain Barrier; Catecholamines; Ch

2002
Alterations in hypothalamic-pituitary-adrenal axis activity and in levels of proopiomelanocortin and corticotropin-releasing hormone-receptor 1 mRNAs in the pituitary and hypothalamus of the rat during chronic 'binge' cocaine and withdrawal.
    Brain research, 2003, Feb-28, Volume: 964, Issue:2

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Amygdala; Animals; Blotting, Northern; Cocaine; Cortico

2003
Amphetamine withdrawal does not produce a depressive-like state in rats as measured by three behavioral tests.
    Behavioural pharmacology, 2003, Volume: 14, Issue:1

    Topics: Adrenocorticotropic Hormone; Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulan

2003
Behavioural and gene transcription alterations induced by spontaneous cannabinoid withdrawal in mice.
    Journal of neurochemistry, 2003, Volume: 85, Issue:1

    Topics: Animals; Autoradiography; Behavior, Animal; Benzoxazines; Binding, Competitive; Body Temperature; Br

2003
Reduced social interaction following 3,4-methylenedioxymethamphetamine is not associated with enhanced 5-HT 2C receptor responsivity.
    Neuropharmacology, 2003, Volume: 44, Issue:4

    Topics: Animals; Brain; Corticosterone; Exploratory Behavior; Hydroxyindoleacetic Acid; Hypothermia; In Vitr

2003
Stress-induced suppression of the immune system after withdrawal from chronic cocaine.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 305, Issue:1

    Topics: Adrenalectomy; Animals; Cell Division; Cocaine; Corticosterone; Disease Models, Animal; Dopamine Upt

2003
Increased CRH mRNA levels in the rat amygdala during short-term withdrawal from chronic 'binge' cocaine.
    Brain research. Molecular brain research, 2003, May-26, Volume: 114, Issue:1

    Topics: Amygdala; Animals; Brain Stem; Chronic Disease; Cocaine; Cocaine-Related Disorders; Corticosterone;

2003
Nicotine withdrawal induces subsensitivity of hypothalamic-pituitary-adrenal axis to stress in rats: implications for precipitation of depression during smoking cessation.
    Psychoneuroendocrinology, 2004, Volume: 29, Issue:2

    Topics: Adaptation, Physiological; Adrenal Cortex Function Tests; Animals; Corticosterone; Depression; Dexam

2004
Immune cell activity during the initial stages of withdrawal from chronic exposure to cocaine or morphine.
    Journal of neuroimmunology, 2004, Volume: 147, Issue:1-2

    Topics: Analysis of Variance; Animals; Cocaine; Concanavalin A; Corticosterone; Lymphocytes; Male; Mitogens;

2004
Anxiolytic-like effects of the corticotropin-releasing factor1 (CRF1) antagonist DMP904 [4-(3-pentylamino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)-pyrazolo-[1,5-a]-pyrimidine] administered acutely or chronically at doses occupying central CRF1 receptors
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 309, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Chlordiazepoxide; Corticosterone; Discrimination Learning; Ma

2004
Behavioral and molecular changes elicited by acute administration of SR141716 to Delta9-tetrahydrocannabinol-tolerant rats: an experimental model of cannabinoid abstinence.
    Drug and alcohol dependence, 2004, May-10, Volume: 74, Issue:2

    Topics: Animals; Arachidonic Acids; Behavior, Animal; Brain; Cannabinoid Receptor Antagonists; Cannabinoid R

2004
Evidence for alterations in alpha2-adrenergic receptor sensitivity in rats exposed to repeated cocaine administration.
    Neuroscience, 2004, Volume: 125, Issue:3

    Topics: Adrenergic alpha-Agonists; Animals; Brain; Clonidine; Cocaine; Cocaine-Related Disorders; Corticoste

2004
Suppressed fever and hypersensitivity responses in chicks prenatally exposed to opiates.
    Brain, behavior, and immunity, 2004, Volume: 18, Issue:6

    Topics: Analysis of Variance; Animals; Basophils; Chick Embryo; Chickens; Corticosterone; Disease Models, An

2004
Spontaneous withdrawal from the triazolobenzodiazepine alprazolam increases cortical corticotropin-releasing factor mRNA expression.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Oct-20, Volume: 24, Issue:42

    Topics: Adrenocorticotropic Hormone; Alprazolam; Animals; Anti-Anxiety Agents; Autoradiography; Body Weight;

2004
Electroacupuncture attenuates morphine withdrawal signs and c-Fos expression in the central nucleus of the amygdala in freely moving rats.
    Brain research, 2005, May-24, Volume: 1044, Issue:2

    Topics: Amygdala; Analysis of Variance; Animals; Behavior, Animal; Cell Count; Corticosterone; Electroacupun

2005
Corticosterone increases damage and cytosolic calcium accumulation associated with ethanol withdrawal in rat hippocampal slice cultures.
    Alcoholism, clinical and experimental research, 2005, Volume: 29, Issue:5

    Topics: Animals; Calcium; Central Nervous System Depressants; Corticosterone; Cytosol; Ethanol; Female; Fluo

2005
Morphine withdrawal contributes to Th cell differentiation by biasing cells toward the Th2 lineage.
    Journal of immunology (Baltimore, Md. : 1950), 2005, Aug-15, Volume: 175, Issue:4

    Topics: Active Transport, Cell Nucleus; Animals; Cell Differentiation; Cell Lineage; Cells, Cultured; Cortic

2005
Previous experience of ethanol withdrawal increases withdrawal-induced c-fos expression in limbic areas, but not withdrawal-induced anxiety and prevents withdrawal-induced elevations in plasma corticosterone.
    Psychopharmacology, 2006, Volume: 185, Issue:2

    Topics: Animals; Anxiety; Corticosterone; Early Growth Response Protein 1; Ethanol; Limbic System; Male; Maz

2006
Sex differences in steroid modulation of ethanol withdrawal in male and female rats.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 320, Issue:1

    Topics: Animals; Corticosterone; Estradiol; Ethanol; Female; Male; Neuroprotective Agents; Ovariectomy; Pent

2007
Cocaine-mediated supersensitivity of 5-HT2A receptors in hypothalamic paraventricular nucleus is a withdrawal-induced phenomenon.
    Neuroscience, 2006, Nov-17, Volume: 143, Issue:1

    Topics: Amphetamines; Animals; Blotting, Western; Cocaine; Corticosterone; Dopamine Uptake Inhibitors; Drug

2006
Mu opioid receptor and orexin/hypocretin mRNA levels in the lateral hypothalamus and striatum are enhanced by morphine withdrawal.
    The Journal of endocrinology, 2006, Volume: 191, Issue:1

    Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Gene Expression; Hypothalamic Area, Lateral; I

2006
Restraint-induced corticosterone secretion and hypothalamic CRH mRNA expression are augmented during acute withdrawal from chronic cocaine administration.
    Neuroscience letters, 2007, Mar-30, Volume: 415, Issue:3

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Corticosterone; Corticotropin-Releasing Hormone; Dopami

2007
Disruption of the CRF/CRF1 receptor stress system exacerbates the somatic signs of opiate withdrawal.
    Neuron, 2007, Feb-15, Volume: 53, Issue:4

    Topics: Analysis of Variance; Animals; Behavior, Animal; Corticosterone; Corticotropin-Releasing Hormone; Di

2007
Sex differences in the effect of finasteride on acute ethanol withdrawal severity in C57BL/6J and DBA/2J mice.
    Neuroscience, 2007, May-25, Volume: 146, Issue:3

    Topics: Acute Disease; Animals; Central Nervous System Depressants; Corticosterone; Data Interpretation, Sta

2007
Involvement of arginine vasopressin and V1b receptor in heroin withdrawal and heroin seeking precipitated by stress and by heroin.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:2

    Topics: Adrenocorticotropic Hormone; Animals; Arginine Vasopressin; Corticosterone; Exploratory Behavior; He

2008
The impact of gonadectomy and adrenalectomy on acute withdrawal severity in male and female C57BL/6J and DBA/2J mice following a single high dose of ethanol.
    Alcoholism, clinical and experimental research, 2007, Volume: 31, Issue:11

    Topics: Animals; Central Nervous System Depressants; Corticosterone; Dose-Response Relationship, Drug; Estra

2007
Decreased anticonvulsant efficacy of allopregnanolone during ethanol withdrawal in female Withdrawal Seizure-Prone vs. Withdrawal Seizure-Resistant mice.
    Neuropharmacology, 2008, Volume: 54, Issue:2

    Topics: Animals; Anticonvulsants; Central Nervous System Depressants; Corticosterone; Estradiol; Ethanol; Fe

2008
L-type calcium channel blockade attenuates morphine withdrawal: in vivo interaction between L-type calcium channels and corticosterone.
    Hormones and behavior, 2008, Volume: 53, Issue:2

    Topics: Adrenalectomy; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Corticosterone; Drug Int

2008
Disruption of the CRF(2) receptor pathway decreases the somatic expression of opiate withdrawal.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:12

    Topics: Animals; Brain; Brain Chemistry; Corticosterone; Disease Models, Animal; Down-Regulation; Female; Ge

2008
Chronic ethanol exposure leads to divergent control of dopaminergic synapses in distinct target regions.
    Alcohol (Fayetteville, N.Y.), 2008, Volume: 42, Issue:3

    Topics: Animals; Biogenic Monoamines; Blotting, Western; Brain Chemistry; Central Nervous System Depressants

2008
Some responses of the immature fowl to the withdrawal of a stressor.
    British poultry science, 1980, Volume: 21, Issue:2

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Animals, Newborn; Body Weight; Chickens; Chole

1980
Ethanol dependence and the pituitary adrenal axis in mice. II. Temporal analysis of dependence and withdrawal.
    Life sciences, 1983, Nov-07, Volume: 33, Issue:19

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Alcoholism; Animals; beta-Endorphin; Corticosterone; En

1983
Effect of naloxone administration upon responses of adrenal hormones to withdrawal from ethanol.
    Psychopharmacology, 1984, Volume: 82, Issue:3

    Topics: Adrenal Cortex; Adrenal Medulla; Animals; Catecholamines; Corticosterone; Dopamine; Epinephrine; Eth

1984
Further studies on the acute dependence produced by morphine in opiate naive rats.
    Life sciences, 1982, Oct-11, Volume: 31, Issue:15

    Topics: Amphetamine; Animals; Corticosterone; Diazepam; Drug Tolerance; Humans; Male; Morphine; Morphine Dep

1982
Effects of naloxone on plasma corticosterone in the opiate-naive rat.
    Life sciences, 1980, Mar-24, Volume: 26, Issue:12

    Topics: Animals; Corticosterone; Humans; Levorphanol; Male; Morphine; Naloxone; Narcotics; Rats; Substance W

1980
Inhibition of rat brain tryptophan metabolism by ethanol withdrawal and possible involvement of the enhanced liver tryptophan pyrrolase activity.
    The Biochemical journal, 1980, Nov-15, Volume: 192, Issue:2

    Topics: Animals; Behavior, Animal; Brain; Corticosterone; Ethanol; Humans; Liver; Male; NAD; Rats; Serotonin

1980
The effects of ethanol on rat liver and brain tryptophan metabolism.
    Substance and alcohol actions/misuse, 1980, Volume: 1, Issue:5-6

    Topics: Alcoholism; Animals; Brain Chemistry; Corticosterone; Ethanol; Humans; Liver; Male; Rats; Rats, Inbr

1980
Evidence for alterations in presynaptic serotonergic function during withdrawal from chronic cocaine in rats.
    European journal of pharmacology, 1995, Aug-25, Volume: 282, Issue:1-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Cocaine; Corticosterone; Fenfluramine

1995
Corticosterone increases severity of acute withdrawal from ethanol, pentobarbital, and diazepam in mice.
    Psychopharmacology, 1994, Volume: 115, Issue:1-2

    Topics: Animals; Behavior, Animal; Corticosterone; Diazepam; Ethanol; Female; Flumazenil; Handling, Psycholo

1994
Quantitative properties of plasma corticosterone elevation induced by naloxone-precipitated withdrawal in morphine-dependent rats.
    Japanese journal of pharmacology, 1994, Volume: 66, Issue:2

    Topics: Analysis of Variance; Animals; Body Weight; Corticosterone; Disease Models, Animal; Dose-Response Re

1994
Immobilization stress-induced oral opioid self-administration and withdrawal in rats: role of conditioning factors and the effect of stress on "relapse" to opioid drugs.
    Psychopharmacology, 1993, Volume: 111, Issue:4

    Topics: Animals; Conditioning, Psychological; Corticosterone; Fentanyl; Immobilization; Male; Morphine; Morp

1993
Effects of intracerebroventricular clonidine on the hypothalamic noradrenaline and plasma corticosterone levels of opiate naive rats and after naloxone-induced withdrawal.
    Brain research, 1994, Jun-06, Volume: 647, Issue:2

    Topics: Animals; Clonidine; Corticosterone; Hypothalamus; Injections, Intraventricular; Male; Morphine Depen

1994
Modulation by catecholamine of hypothalamus-pituitary-adrenocortical (HPA) axis activity in morphine-tolerance and withdrawal.
    General pharmacology, 1994, Volume: 25, Issue:1

    Topics: Animals; Corticosterone; Dopamine; Drug Implants; Drug Tolerance; Hypothalamo-Hypophyseal System; Ma

1994
Modification of behavioral effects of 8-hydroxy-2-(di-n-propylamino)tetralin following chronic ethanol consumption in the rat: evidence for the involvement of 5-HT1A receptors in ethanol dependence.
    European journal of pharmacology, 1995, Aug-15, Volume: 281, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Corticosterone; Dose-Response Rel

1995
No relation of plasma morphine level to the severity of naloxone-induced withdrawal in acute morphine-dependent rats.
    Japanese journal of pharmacology, 1995, Volume: 69, Issue:3

    Topics: Animals; Body Weight; Corticosterone; Dose-Response Relationship, Drug; Male; Morphine; Naloxone; Ra

1995
Neurosteroids and the naloxone-precipitated withdrawal syndrome in morphine-dependent mice.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1996, Volume: 6, Issue:2

    Topics: 5-alpha-Dihydroprogesterone; Animals; Behavior, Animal; Corticosterone; Dehydroepiandrosterone; Deso

1996
Possible involvement of the total amount of morphine infused in the development of acute morphine dependence in rats.
    Japanese journal of pharmacology, 1996, Volume: 70, Issue:1

    Topics: Acute Disease; Analysis of Variance; Animals; Corticosterone; Diarrhea; Infusions, Intravenous; Male

1996
Chronic naloxone-induced supersensitivity affects neither tolerance to nor physical dependence on morphine at hypothalamus-pituitary-adrenocortical axis.
    Neuropeptides, 1996, Volume: 30, Issue:1

    Topics: Animals; Behavior, Animal; Corticosterone; Drug Tolerance; Hypothalamo-Hypophyseal System; Male; Mor

1996
Diltiazem inhibits naloxone-precipitated and spontaneous morphine withdrawal in rats.
    European journal of pharmacology, 1996, Nov-28, Volume: 316, Issue:1

    Topics: Animals; Body Weight; Calcium Channel Blockers; Corticosterone; Diarrhea; Diltiazem; Drug Interactio

1996
Chronic alcohol consumption and withdrawal do not induce cell death in the suprachiasmatic nucleus, but lead to irreversible depression of peptide immunoreactivity and mRNA levels.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Feb-15, Volume: 17, Issue:4

    Topics: Alcohol Drinking; Animals; Astrocytes; Body Weight; Brain; Cell Death; Corticosterone; Ethanol; Male

1997
Activation of corticotropin-releasing factor in the limbic system during cannabinoid withdrawal.
    Science (New York, N.Y.), 1997, Jun-27, Volume: 276, Issue:5321

    Topics: Amygdala; Animals; Anxiety; Behavior, Animal; Brain; Corticosterone; Corticotropin-Releasing Hormone

1997
Sex differences in effects of predictable and unpredictable footshock on fentanyl self-administration in rats.
    Experimental and clinical psychopharmacology, 1997, Volume: 5, Issue:2

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Conditioning, Operant; Corticosterone; Electroshock;

1997
Gluconeogenic activity in response to chronic administration of amphetamine sulphate and drug withdrawal.
    General pharmacology, 1997, Volume: 29, Issue:4

    Topics: Adrenocorticotropic Hormone; Alanine Transaminase; Amphetamine; Animals; Aspartate Aminotransferases

1997
Increased motor response to cocaine administration following recovery from chronic corticosterone treatment in the rat.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1998, Volume: 8, Issue:1

    Topics: Animals; Cocaine; Corticosterone; Dopamine Uptake Inhibitors; Male; Motor Activity; Rats; Rats, Wist

1998
Stress-induced cross-sensitization to cocaine: effect of adrenalectomy and corticosterone after short- and long-term withdrawal.
    Psychopharmacology, 1998, Volume: 136, Issue:1

    Topics: Adrenalectomy; Animals; Cocaine; Corticosterone; Dopamine Uptake Inhibitors; Environment; Male; Moto

1998
Alterations in corticotropin-releasing factor and vasopressin content in rat brain during morphine withdrawal: correlation with hypothalamic noradrenergic activity and pituitary-adrenal response.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 285, Issue:2

    Topics: Animals; Arginine Vasopressin; Brain Chemistry; Corticosterone; Corticotropin-Releasing Hormone; Hyp

1998
Time course of morphine withdrawal and preproenkephalin gene expression in the periaqueductal gray of rats.
    Brain research. Molecular brain research, 1998, Volume: 55, Issue:2

    Topics: Animals; Body Weight; Corticosterone; Enkephalins; Gene Expression Regulation; Injections, Subcutane

1998
Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1.
    Nature genetics, 1998, Volume: 19, Issue:2

    Topics: Adrenocorticotropic Hormone; Animals; Anxiety; Cells, Cultured; Corticosterone; Ethanol; In Situ Hyb

1998
Changes in right atrial catecholamine content in naïve rats and after naloxone-induced withdrawal.
    British journal of anaesthesia, 1998, Volume: 80, Issue:3

    Topics: Animals; Catecholamines; Corticosterone; Drug Administration Schedule; Drug Tolerance; Heart Atria;

1998
Lack of sex differences in anxiety behaviors during precipitated benzodiazepine withdrawal in rats.
    Physiology & behavior, 1999, Volume: 66, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Corticosterone; Diazepam; Estradiol; Female; Flumazenil; GABA

1999
Noradrenergic and dopaminergic activity in the hypothalamic paraventricular nucleus after naloxone-induced morphine withdrawal.
    Neuroendocrinology, 2000, Volume: 71, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Behavior, Animal; Body Weight; Chroni

2000
Effects of U-50,488H and U-50,488H withdrawal on catecholaminergic neurons of the rat hypothalamus.
    Life sciences, 2000, Jan-21, Volume: 66, Issue:9

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; 3,4-Dihydr

2000
The novel 5-Hydroxytryptamine(1A) antagonist LY426965: effects on nicotine withdrawal and interactions with fluoxetine.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Animals; Body Temperature; Columbidae;

2000
Effects of adolescent nicotine exposure on opioid consumption and neuroendocrine responses in adult male and female rats.
    Experimental and clinical psychopharmacology, 2001, Volume: 9, Issue:3

    Topics: Adrenocorticotropic Hormone; Aging; Analgesics, Opioid; Animals; Body Weight; Corticosterone; Drinki

2001
Differential responsivity of the hypothalamic-pituitary-adrenal axis to glucocorticoid negative-feedback and corticotropin releasing hormone in rats undergoing morphine withdrawal: possible mechanisms involved in facilitated and attenuated stress response
    Journal of neuroendocrinology, 2001, Volume: 13, Issue:10

    Topics: Adrenocorticotropic Hormone; Analgesics, Opioid; Animals; Area Under Curve; Blotting, Western; Corti

2001
Corticosterone concentrations in mice during ethanol drinking and withdrawal.
    The Journal of pharmacy and pharmacology, 1978, Volume: 30, Issue:6

    Topics: Alcoholism; Animals; Circadian Rhythm; Corticosterone; Ethanol; Humans; Male; Mice; Substance Withdr

1978
Effects of nicotine administration and its withdrawal on plasma corticosterone and brain 5-hydroxyindoles.
    Psychopharmacology, 1979, May-08, Volume: 63, Issue:1

    Topics: Animals; Brain; Corticosterone; Hippocampus; Humans; Hydroxyindoleacetic Acid; Hypothalamus; Male; N

1979
Brain catecholamines and ethanol: involvement in physical dependence and withdrawal.
    Advances in experimental medicine and biology, 1977, Volume: 85A

    Topics: Alcoholism; Animals; Body Temperature; Brain Chemistry; Corticosterone; Ethanol; Humans; Male; Motor

1977
Alcohol intoxication and withdrawal in inbred strains of mice: behavioral and endocrine studies.
    Behavioral and neural biology, 1979, Volume: 26, Issue:1

    Topics: Alcoholic Intoxication; Alcoholism; Animals; Behavior, Animal; Corticosterone; Ethanol; Genotype; Hu

1979
The involvement of corticosteroids in the supersensitivity produced in the rat anococcygeus muscle by morphine withdrawal, thyroidectomy or a single dose of reserpine.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 192, Issue:2

    Topics: Acetylcholine; Adrenalectomy; Animals; Body Weight; Corticosterone; Humans; In Vitro Techniques; Mal

1975
Reduction in the cholinesterase activity of the rat anococcygeus muscle produced by corticosterone.
    British journal of pharmacology, 1975, Volume: 55, Issue:1

    Topics: Adrenal Glands; Adrenalectomy; Animals; Cholinesterases; Corticosterone; Depression, Chemical; Human

1975
Genetic differences in hypothalamic-pituitary-adrenal axis responsiveness to acute ethanol and acute ethanol withdrawal.
    Brain research, 1992, May-08, Volume: 579, Issue:2

    Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Ethanol; Handling, Psychological; Hypothalamo-

1992
Role of the adrenal gland in the thermal response to morphine withdrawal in rats.
    Canadian journal of physiology and pharmacology, 1992, Volume: 70, Issue:8

    Topics: Adrenal Cortex; Adrenal Glands; Adrenal Medulla; Adrenalectomy; Animals; Body Temperature; Body Weig

1992
Attenuation of the morphine withdrawal syndrome by inhibition of catabolism of endogenous enkephalins in the periaqueductal gray matter.
    Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 345, Issue:4

    Topics: Analgesics; Animals; Behavior, Animal; Body Temperature; Body Weight; Corticosterone; Dipeptides; En

1992
Effects of specific mu and kappa opiate tolerance and abstinence on hypothalamo-pituitary-adrenal axis secretion in the rat.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenocort

1990
The effects of diazepam on brain 5-HT and 5-HIAA in stressed and unstressed rats.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 27, Issue:4

    Topics: Altitude; Animals; Brain; Cerebral Cortex; Corticosterone; Diazepam; Habituation, Psychophysiologic;

1987
Effects of beta-carboline-ethyl ester on plasma corticosterone--a parallel with antagonist-precipitated diazepam withdrawal.
    Life sciences, 1989, Volume: 44, Issue:20

    Topics: Animals; Behavior, Animal; Benzodiazepines; Carbolines; Corticosterone; Diazepam; Kinetics; Male; Py

1989
Effects of withdrawal from chronic exposure to cigarette smoke on hypothalamic and preoptic catecholamine nerve terminal systems and on the secretion of pituitary hormones in the male rat.
    Naunyn-Schmiedeberg's archives of pharmacology, 1989, Volume: 339, Issue:4

    Topics: Animals; Catecholamines; Corticosterone; Cotinine; Hypothalamus; Male; Nerve Endings; Nicotine; Nore

1989
Comparison of selective and complete inhibitors of enkephalin-degrading enzymes on morphine withdrawal syndrome.
    European journal of pharmacology, 1989, Jun-20, Volume: 165, Issue:2-3

    Topics: Animals; Behavior, Animal; Body Temperature; Body Weight; Corticosterone; Dipeptides; Hydroxamic Aci

1989
Mianserin attenuates naloxone-precipitated withdrawal signs in rats acutely or chronically dependent upon morphine.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 236, Issue:1

    Topics: Animals; Body Temperature; Clonidine; Corticosterone; Dibenzazepines; Male; Mianserin; Morphine Depe

1986
Central histaminergic stimulation of corticosterone and hyperlipemic responses after chronic ethanol consumption in rats.
    Agents and actions, 1987, Volume: 20, Issue:3-4

    Topics: Animals; Corticosterone; Ethanol; Fatty Acids, Nonesterified; Male; Pituitary-Adrenal System; Rats;

1987
Diazepam withdrawal as demonstrated by changes in plasma corticosterone: a role for the hippocampus.
    Life sciences, 1987, Mar-02, Volume: 40, Issue:9

    Topics: Animals; Cerebral Ventricles; Corticosterone; Diazepam; Drug Implants; Hippocampus; Male; Rats; Rats

1987
Prolonged protective effects following propranolol withdrawal against isoproterenol-induced myocardial infarction in normotensive and hypertensive rats.
    British journal of experimental pathology, 1985, Volume: 66, Issue:2

    Topics: Animals; Blood Pressure; Corticosterone; Creatine Kinase; Female; Humans; Isoproterenol; L-Lactate D

1985
Effects of chronic treatment with diazepam, phenobarbital, or amphetamine on naloxone-precipitated morphine withdrawal.
    Drug and alcohol dependence, 1985, Volume: 15, Issue:4

    Topics: Amphetamine; Animals; Corticosterone; Diazepam; Male; Mice; Morphine Dependence; Motor Activity; Nal

1985
[Dependence on central analgesics. 2. Relationship between alteration of the mitochondria of the zona fasciculata of the rat due to morphine dependence and corticosterone metabolism].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1971, Volume: 46, Issue:5

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Ascorbic Acid; Corticosterone; Depression, Che

1971
Reversal of the action of morphine on the secretory activity of the adrenal cortex.
    Biochemical pharmacology, 1974, Volume: 23, Issue:15

    Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenal Glands; Animals; Birefringence; Cholesterol; Cortic

1974
Adrenal glucocorticoids as a required factor in the development of ethanol withdrawal seizures in mice.
    Brain research, 1974, Nov-08, Volume: 80, Issue:1

    Topics: Adrenal Glands; Alcoholic Intoxication; Animals; Corticosterone; Humans; Male; Mice; Mice, Inbred St

1974
Studies on the physical dependence liability of anlgesics. 2. Relationship between transformation of intramitochondrial structures in adrenocortical cells and corticosterone biosynthesis in morphine addicted rats.
    Japanese journal of pharmacology, 1973, Volume: 23, Issue:2

    Topics: Adrenal Glands; Animals; Ascorbic Acid; Corticosterone; Humans; Male; Mitochondria; Morphine Depende

1973
Morphine analgesia, tolerance and physical dependence in the adrenalectomized rat.
    British journal of pharmacology, 1973, Volume: 47, Issue:4

    Topics: Adrenal Glands; Adrenalectomy; Analgesia; Animals; Body Weight; Corticosterone; Drug Tolerance; Huma

1973
Some endocrinological aspects of barbiturate dependence.
    British journal of pharmacology, 1971, Volume: 41, Issue:2

    Topics: Adrenal Glands; Animals; Barbiturates; Body Weight; Corticosterone; Endocrine Glands; Female; Frustr

1971