corticosterone has been researched along with Drug Withdrawal Symptoms in 154 studies
Excerpt | Relevance | Reference |
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" Clonazepam, a commonly prescribed benzodiazepine, has been increasingly used as a countermeasure to cocaine side-effects, including sleep reduction and anxiety." | 7.96 | Combined cocaine and clonazepam administration induces REM sleep loss and anxiety-like withdrawal behaviors in rats. ( Andersen, ML; Dokkedal-Silva, V; Galduróz, JCF; Tufik, S, 2020) |
" This study aims to investigate the potential effects of hydrogen-rich saline (HRS) administration on naloxone-precipitated withdrawal symptoms and morphine withdrawal-induced anxiety-like behaviors." | 7.85 | Hydrogen-rich saline attenuates anxiety-like behaviors in morphine-withdrawn mice. ( Cong, B; Gong, M; Guo, H; Hui, R; Ma, C; Shen, Q; Wang, J; Wen, D; Zhao, P, 2017) |
"The aim of the present study was to investigate the effects of the selective agonists of the corticotropin-releasing factor (CRF) 2 receptor, urocortin 2 (UCN 2) and urocortin 3 (UCN 3), on the anxiety- and depression-like signs induced by acute nicotine withdrawal in mice." | 7.83 | Selective CRF2 receptor agonists ameliorate the anxiety- and depression-like state developed during chronic nicotine treatment and consequent acute withdrawal in mice. ( Bagosi, Z; Balangó, B; Bokor, P; Buzás, A; Csabafi, K; Jászberényi, M; Palotai, M; Pintér, D; Simon, B; Szabó, G, 2016) |
" Basally, HRs display lower anxiety-like behavior compared to LRs along with higher neuropeptide Y (NPY) mRNA in the amygdala and the hippocampus." | 7.77 | Effects of a selective Y2R antagonist, JNJ-31020028, on nicotine abstinence-related social anxiety-like behavior, neuropeptide Y and corticotropin releasing factor mRNA levels in the novelty-seeking phenotype. ( Aydin, C; Isgor, C; Oztan, O, 2011) |
"Acute amphetamine administration activates monoaminergic pathways and increases systemic corticosterone, both of which influence anxiety states and adult dentate gyrus neurogenesis." | 7.76 | Withdrawal from chronic amphetamine produces persistent anxiety-like behavior but temporally-limited reductions in monoamines and neurogenesis in the adult rat dentate gyrus. ( Barr, JL; Forster, GL; Renner, KJ, 2010) |
" Eight hours after ethanol withdrawal, anxiety-like behaviour was tested in the elevated plus-maze, blood corticosterone levels were measured, and expression level of markers of neuronal activity and plasticity, c-fos and zif268, was assessed." | 7.73 | Previous experience of ethanol withdrawal increases withdrawal-induced c-fos expression in limbic areas, but not withdrawal-induced anxiety and prevents withdrawal-induced elevations in plasma corticosterone. ( Borlikova, GG; Le Merrer, J; Stephens, DN, 2006) |
") was challenged 18 hr after infusion was stopped, and the withdrawal was evaluated by plasma corticosterone (PCS) increase, diarrhea and body weight loss." | 7.69 | Possible involvement of the total amount of morphine infused in the development of acute morphine dependence in rats. ( Fukunaga, Y; Inoue, N; Kishioka, S; Nishida, S; Yamamoto, H, 1996) |
" Seven days later, the animals were challenged with a dose of isoproterenol which would produce massive myocardial infarction and 50-60% mortality in non-treated animals." | 7.67 | Prolonged protective effects following propranolol withdrawal against isoproterenol-induced myocardial infarction in normotensive and hypertensive rats. ( Wexler, BC, 1985) |
" Clonazepam, a commonly prescribed benzodiazepine, has been increasingly used as a countermeasure to cocaine side-effects, including sleep reduction and anxiety." | 3.96 | Combined cocaine and clonazepam administration induces REM sleep loss and anxiety-like withdrawal behaviors in rats. ( Andersen, ML; Dokkedal-Silva, V; Galduróz, JCF; Tufik, S, 2020) |
"Chronic methamphetamine (MA) use can lead to increased symptoms of depression and anxiety during abstinence." | 3.91 | Stress-induced neural activation is altered during early withdrawal from chronic methamphetamine. ( Brooks, ML; Jacobskind, JS; Rosinger, ZJ; Zuloaga, DG, 2019) |
" Rats were tested on social interaction, a measure of anxiety-like behavior, followed immediately by collection of amygdala tissue to measure CCL2 and TNFα or collection of the blood to measure corticosterone (CORT)." | 3.88 | Differential effects of single versus repeated minocycline administration-Lack of significant interaction with chronic alcohol history. ( Breese, GR; Harper, KM; Knapp, DJ; Park, MA, 2018) |
" This study aims to investigate the potential effects of hydrogen-rich saline (HRS) administration on naloxone-precipitated withdrawal symptoms and morphine withdrawal-induced anxiety-like behaviors." | 3.85 | Hydrogen-rich saline attenuates anxiety-like behaviors in morphine-withdrawn mice. ( Cong, B; Gong, M; Guo, H; Hui, R; Ma, C; Shen, Q; Wang, J; Wen, D; Zhao, P, 2017) |
"The aim of the present study was to investigate the effects of the selective agonists of the corticotropin-releasing factor (CRF) 2 receptor, urocortin 2 (UCN 2) and urocortin 3 (UCN 3), on the anxiety- and depression-like signs induced by acute nicotine withdrawal in mice." | 3.83 | Selective CRF2 receptor agonists ameliorate the anxiety- and depression-like state developed during chronic nicotine treatment and consequent acute withdrawal in mice. ( Bagosi, Z; Balangó, B; Bokor, P; Buzás, A; Csabafi, K; Jászberényi, M; Palotai, M; Pintér, D; Simon, B; Szabó, G, 2016) |
" We analysed the time course of the global withdrawal score, the anxiety-like effects, monoamine concentrations, the brain-derived neurotrophic factor (BDNF) expression, the corticosterone plasmatic levels and [(3)H]epibatidine binding sites during NIC withdrawal precipitated by mecamylamine, a nicotinic receptor antagonist (MEC)." | 3.81 | Lack of GABAB receptors modifies behavioural and biochemical alterations induced by precipitated nicotine withdrawal. ( Antonelli, MC; Balerio, GN; Bettler, B; Machado, LM; Pedrón, VT; Varani, AP, 2015) |
" The aggravation of alcohol withdrawal symptoms, such as anxiety, has been associated with increased levels of serum corticosterone and leptin." | 3.81 | N-acetylcysteine prevents behavioral and biochemical changes induced by alcohol cessation in rats. ( Clarimundo, V; Dalmaz, C; Elisabetsky, E; Gomez, R; Santos, CF; Schneider, R, 2015) |
" Basally, HRs display lower anxiety-like behavior compared to LRs along with higher neuropeptide Y (NPY) mRNA in the amygdala and the hippocampus." | 3.77 | Effects of a selective Y2R antagonist, JNJ-31020028, on nicotine abstinence-related social anxiety-like behavior, neuropeptide Y and corticotropin releasing factor mRNA levels in the novelty-seeking phenotype. ( Aydin, C; Isgor, C; Oztan, O, 2011) |
"Acute amphetamine administration activates monoaminergic pathways and increases systemic corticosterone, both of which influence anxiety states and adult dentate gyrus neurogenesis." | 3.76 | Withdrawal from chronic amphetamine produces persistent anxiety-like behavior but temporally-limited reductions in monoamines and neurogenesis in the adult rat dentate gyrus. ( Barr, JL; Forster, GL; Renner, KJ, 2010) |
" Nifedipine, as a calcium channel blocker, can attenuate the development of morphine dependence; however, the role of the HPA axis in this effect has not been elucidated." | 3.74 | L-type calcium channel blockade attenuates morphine withdrawal: in vivo interaction between L-type calcium channels and corticosterone. ( Ahmadiani, A; Esmaeili-Mahani, S; Fathi, Y; Hosseinpanah, F; Motamedi, F, 2008) |
" Eight hours after ethanol withdrawal, anxiety-like behaviour was tested in the elevated plus-maze, blood corticosterone levels were measured, and expression level of markers of neuronal activity and plasticity, c-fos and zif268, was assessed." | 3.73 | Previous experience of ethanol withdrawal increases withdrawal-induced c-fos expression in limbic areas, but not withdrawal-induced anxiety and prevents withdrawal-induced elevations in plasma corticosterone. ( Borlikova, GG; Le Merrer, J; Stephens, DN, 2006) |
"Administration of amphetamine (AMPH) can induce symptoms of psychosis in humans and locomotor sensitization in rats; in contrast, withdrawal from a period of AMPH intake is most often associated with symptoms of human endogenous depression." | 3.72 | Amphetamine withdrawal does not produce a depressive-like state in rats as measured by three behavioral tests. ( Feldon, J; Murphy, CA; Nanz-Bahr, NI; Pezze, MA; Pryce, CR; Russig, H, 2003) |
" We then measured the corticosterone and fever responses to LPS stimulation during the withdrawal period." | 3.72 | Suppressed fever and hypersensitivity responses in chicks prenatally exposed to opiates. ( Schrott, LM; Sparber, SB, 2004) |
" The increase of plasma corticosterone (PCS: 52 and 52 microg/100 ml; control group, 18 and 15 microg/100 ml) and body weight loss (-6 and -9%; control group, 0 and -1%) were observed but PPE mRNA increase was not detected 1 and 2 h after naloxone in morphine treated rats." | 3.70 | Time course of morphine withdrawal and preproenkephalin gene expression in the periaqueductal gray of rats. ( Fukunaga, Y; Inoue, N; Kishioka, S; Miyamoto, M; Nishida, S; Yamamoto, H, 1998) |
") was challenged 18 hr after infusion was stopped, and the withdrawal was evaluated by plasma corticosterone (PCS) increase, diarrhea and body weight loss." | 3.69 | Possible involvement of the total amount of morphine infused in the development of acute morphine dependence in rats. ( Fukunaga, Y; Inoue, N; Kishioka, S; Nishida, S; Yamamoto, H, 1996) |
"Plasma morphine concentration and naloxone-precipitated withdrawal body weight loss and plasma corticosterone (PCS) increase were determined at 12, 18 and 24 hr after i." | 3.69 | No relation of plasma morphine level to the severity of naloxone-induced withdrawal in acute morphine-dependent rats. ( Fukunaga, Y; Inoue, N; Kishioka, S; Nishida, S; Yamamoto, H, 1995) |
" The dose-dependent effects of naloxone on PCS and body weight were studied in male Sprague-Dawley rats rendered physically dependent on morphine by injecting increasing doses of 40-120 mg/kg/day, s." | 3.69 | Quantitative properties of plasma corticosterone elevation induced by naloxone-precipitated withdrawal in morphine-dependent rats. ( Fukunaga, Y; Kishioka, S; Nishida, S; Yamamoto, H, 1994) |
" In naloxone-precipitated withdrawal, body weight loss and plasma corticosterone elevation were dose dependently inhibited by diltiazem injected 4 or 2 and 4 h before naloxone, respectively." | 3.69 | Diltiazem inhibits naloxone-precipitated and spontaneous morphine withdrawal in rats. ( Fukunaga, Y; Inoue, N; Kishioka, S; Nishida, S; Yamamoto, H, 1996) |
" Seven days later, the animals were challenged with a dose of isoproterenol which would produce massive myocardial infarction and 50-60% mortality in non-treated animals." | 3.67 | Prolonged protective effects following propranolol withdrawal against isoproterenol-induced myocardial infarction in normotensive and hypertensive rats. ( Wexler, BC, 1985) |
"The effects of the atypical antidepressant and serotonin antagonist mianserin on the expression of opiate withdrawal was examined using an acute and a chronic model of morphine dependence." | 3.67 | Mianserin attenuates naloxone-precipitated withdrawal signs in rats acutely or chronically dependent upon morphine. ( Neal, BS; Sparber, SB, 1986) |
" In morphine-dependent animals, the incidence of abstinence signs and body weight loss during precipitated withdrawal did not appear to be significantly influenced by adrenalectomy or by corticosterone-pretreatment." | 3.65 | Morphine analgesia, tolerance and physical dependence in the adrenalectomized rat. ( Wei, E, 1973) |
"Vigorous control of withdrawal and PTSD-related arousal symptoms should be sought during detoxification of patients with comorbid PTSD and substance use disorders." | 2.41 | Substance use disorders in patients with posttraumatic stress disorder: a review of the literature. ( Jacobsen, LK; Kosten, TR; Southwick, SM, 2001) |
"Morphine has been shown to increase the expression of brain-derived neurotrophic factor (BDNF) in the brain." | 1.56 | Conditioned aversive memory associated with morphine withdrawal increases brain-derived neurotrophic factor in dentate gyrus and basolateral amygdala. ( Almela, P; Laorden, ML; Martínez-Laorden, E; Milanés, MV; Navarro-Zaragoza, J, 2020) |
"Corticosterone was not elevated at withdrawal." | 1.51 | Withdrawal from Brief Repeated Alcohol Treatment in Adolescent and Adult Male and Female Rats. ( Chandra, U; Fleming, W; Francis, R; Jones, Q; Kuhn, C; Ocampo, G; Saini, A; Walker, D, 2019) |
"Alcohol dependence is linked to dysregulation of the hypothalamic-pituitary-adrenal axis." | 1.46 | Abstinence from prolonged ethanol exposure affects plasma corticosterone, glucocorticoid receptor signaling and stress-related behaviors. ( Contet, C; Fannon, MJ; Guevara, J; Mandyam, CD; Nguyen, TB; Schmeichel, BE; Sidhu, H; Somkuwar, SS; Vendruscolo, LF; Zorrilla, EP, 2017) |
"The key problem in treating cocaine addiction is the maintenance of a drug-free state as negative emotional symptoms during abstinence often trigger relapse." | 1.43 | Cocaine abstinence induces emotional impairment and brain region-specific upregulation of the oxytocin receptor binding. ( Bailey, A; Georgiou, P; Hourani, S; Kitchen, I; Zanos, P, 2016) |
"Although no physical withdrawal symptoms or alterations in the plasma corticosterone levels were observed after 7 days of abstinence, mice exhibited increased anxiety-like and depressive-like behaviors and impaired sociability." | 1.40 | The oxytocin analogue carbetocin prevents emotional impairment and stress-induced reinstatement of opioid-seeking in morphine-abstinent mice. ( Bailey, A; Georgiou, P; Hourani, SM; Kitchen, I; Winsky-Sommerer, R; Wright, SR; Zanos, P, 2014) |
"Corticosterone levels were significantly different at the end of the 15-min session, but not following the 2-h session." | 1.39 | Combinations of oxazepam and metyrapone attenuate cocaine and methamphetamine cue reactivity. ( Cornett, EM; Goeders, NE; Guerin, GF; Keller, CM, 2013) |
"Corticosterone concentration was increased in brain and blood of mice during abstinence phase and pretreatment with nimodipine prevented the increase in brain and blood corticosterone concentration." | 1.38 | The effect of nimodipine on memory impairment during spontaneous morphine withdrawal in mice: Corticosterone interaction. ( Hajhashemi, V; Rabbani, M; Vaseghi, G, 2012) |
"Morphine withdrawal was precipitated on day 8 by the injection of naloxone (2 mg/kg s." | 1.38 | Morphine withdrawal activates hypothalamic-pituitary-adrenal axis and heat shock protein 27 in the left ventricle: the role of extracellular signal-regulated kinase. ( Almela, P; Hurle, MA; Laorden, ML; Martínez-Laorden, E; Milanés, MV, 2012) |
"The role of stress in drug addiction is well established." | 1.36 | Effects of corticotropin-releasing factor receptor-1 antagonists on the brain stress system responses to morphine withdrawal. ( Laorden, ML; Milanés, MV; Navarro-Zaragoza, J; Núñez, C, 2010) |
"Cocaine addiction is known to impair immune system function, but the effects of repeated treatment with cocaine in a self-administration model, its withdrawal as well as reinstatement of cocaine-seeking behavior on cell-mediated immunity are not well known." | 1.35 | Immunosuppression induced by a conditioned stimulus associated with cocaine self-administration. ( Basta-Kaim, A; Budziszewska, B; Filip, M; Jaworska-Feil, L; Kubera, M; Lason, W; Leskiewicz, M; Machowska, A; Przegalinski, E; Regulska, M; Wydra, K, 2008) |
"Both nimodipine treatments prevented the memory deficits when these were measured between 1 and 2 months after alcohol withdrawal." | 1.35 | Nimodipine prior to alcohol withdrawal prevents memory deficits during the abstinence phase. ( Brooks, SP; Croft, AP; Little, HJ; Norman, G; Shaw, SG, 2008) |
"To induce opiate dependence, mice were treated with intermittent escalating morphine doses (20-100 mg/kg, i." | 1.35 | Disruption of the CRF(2) receptor pathway decreases the somatic expression of opiate withdrawal. ( Contarino, A; Ghozland, S; Ingallinesi, M; Koob, GF; Papaleo, F; Roberts, AJ, 2008) |
"In contrast, the seizure prone DBA/2J inbred strain and the Withdrawal Seizure-Prone (WSP) selected line exhibited decreased sensitivity to ALLO's anticonvulsant effect during ethanol withdrawal, with no change in sensitivity in the Withdrawal Seizure-Resistant (WSR) line." | 1.35 | Decreased anticonvulsant efficacy of allopregnanolone during ethanol withdrawal in female Withdrawal Seizure-Prone vs. Withdrawal Seizure-Resistant mice. ( Beckley, EH; Crabbe, JC; Finn, DA; Fretwell, AM; Gililland, KR; Tanchuck, MA, 2008) |
"Corticosterone levels were unchanged by alcohol consumption, but they were decreased by withdrawal in females." | 1.35 | Sexually dimorphic response of the hypothalamo-pituitary-adrenal axis to chronic alcohol consumption and withdrawal. ( Madeira, MD; Santos-Marques, MJ; Silva, SM, 2009) |
"Corticosterone concentration was normalized 14 h after the last dose of morphine." | 1.35 | Increase in brain corticosterone concentration and recognition memory impairment following morphine withdrawal in mice. ( Hajhashemi, V; Mesripour, A; Rabbani, M, 2009) |
"Handling-induced convulsions (HICs) were scored at baseline, and then over a 24 h period after EtOH or saline injection." | 1.34 | Sex differences in the effect of finasteride on acute ethanol withdrawal severity in C57BL/6J and DBA/2J mice. ( Finn, DA; Gorin-Meyer, RE; Long, SL; Tanchuck, MA; Wiren, KM; Yoneyama, N, 2007) |
"Corticosterone levels were also significantly higher in restrained animals after EA stimulation." | 1.33 | Electroacupuncture attenuates morphine withdrawal signs and c-Fos expression in the central nucleus of the amygdala in freely moving rats. ( Liu, H; Liu, S; Yang, G; Zhao, W; Zhou, W, 2005) |
" Previous studies revealed that chronic administration of the anxiolytic alprazolam reduced indices of CRF and CRF1 receptor function." | 1.32 | Spontaneous withdrawal from the triazolobenzodiazepine alprazolam increases cortical corticotropin-releasing factor mRNA expression. ( Nemeroff, CB; Owens, MJ; Skelton, KH, 2004) |
" In the present work we have studied the effects of acute and chronic administration of the kappa agonist U-50,488H as well as the influence of U-50,488H withdrawal on the activity of hypothalamic NA and dopamine (DA) neurons and on the activity of hypothalamic-pituitary-adrenal (HPA) axis." | 1.31 | Effects of U-50,488H and U-50,488H withdrawal on catecholaminergic neurons of the rat hypothalamus. ( Laorden, ML; Milanés, MV, 2000) |
"Corticosterone levels were positively correlated with fentanyl SA." | 1.30 | Sex differences in effects of predictable and unpredictable footshock on fentanyl self-administration in rats. ( Grunberg, NE; Klein, LC; Popke, EJ, 1997) |
"These results suggest that withdrawal convulsions following acute ethanol, pentobarbital, and diazepam are sensitive to modulation by corticosterone and they support the hypothesis that stress may increase drug withdrawal severity." | 1.29 | Corticosterone increases severity of acute withdrawal from ethanol, pentobarbital, and diazepam in mice. ( Crabbe, JC; Keith, LD; Roberts, AJ, 1994) |
"Diazepam has been shown to produce physical dependence based on observations of behavioral stimulation or, in our laboratory, by increases in plasma corticosterone (CS) during antagonist-precipitated withdrawal." | 1.28 | Effects of beta-carboline-ethyl ester on plasma corticosterone--a parallel with antagonist-precipitated diazepam withdrawal. ( Eisenberg, RM; Johnson, C, 1989) |
"Ethanol withdrawal symptoms followed the removal of ethanol from the diet and circulating corticosterone concentrations were further increased." | 1.26 | Corticosterone concentrations in mice during ethanol drinking and withdrawal. ( Jafee, RC; Ritzmann, RF; Tabakoff, B, 1978) |
"3." | 1.26 | Some responses of the immature fowl to the withdrawal of a stressor. ( Flack, IH; Freeman, BM; Manning, AC, 1980) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 28 (18.18) | 18.7374 |
1990's | 27 (17.53) | 18.2507 |
2000's | 46 (29.87) | 29.6817 |
2010's | 47 (30.52) | 24.3611 |
2020's | 6 (3.90) | 2.80 |
Authors | Studies |
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Vassoler, FM | 1 |
Isgate, SB | 1 |
Budge, KE | 1 |
Byrnes, EM | 1 |
Islas-Preciado, D | 1 |
Ugalde-Fuentes, G | 1 |
Sollozo-Dupont, I | 1 |
González Trujano, ME | 1 |
Cervantes-Anaya, N | 1 |
Estrada-Camarena, E | 1 |
López-Rubalcava, C | 1 |
Cruz, B | 1 |
Castañeda, K | 1 |
Aranda, M | 1 |
Hinojosa, CA | 1 |
Castro-Gutierrez, R | 1 |
Flores, RJ | 1 |
Spencer, CT | 1 |
Vozella, V | 1 |
Roberto, M | 1 |
Gadad, BS | 1 |
Roychowdhury, S | 1 |
O'Dell, LE | 1 |
Bray, B | 2 |
Clement, KA | 1 |
Bachmeier, D | 1 |
Weber, MA | 1 |
Forster, GL | 3 |
Dokkedal-Silva, V | 1 |
Galduróz, JCF | 1 |
Tufik, S | 1 |
Andersen, ML | 1 |
Wen, D | 1 |
Zhao, P | 1 |
Hui, R | 1 |
Wang, J | 1 |
Shen, Q | 1 |
Gong, M | 1 |
Guo, H | 1 |
Cong, B | 1 |
Ma, C | 1 |
Somkuwar, SS | 1 |
Vendruscolo, LF | 1 |
Fannon, MJ | 1 |
Schmeichel, BE | 1 |
Nguyen, TB | 1 |
Guevara, J | 1 |
Sidhu, H | 1 |
Contet, C | 1 |
Zorrilla, EP | 1 |
Mandyam, CD | 1 |
Domi, E | 1 |
Barbier, E | 1 |
Augier, E | 1 |
Augier, G | 1 |
Gehlert, D | 1 |
Barchiesi, R | 1 |
Thorsell, A | 1 |
Holm, L | 1 |
Heilig, M | 1 |
Harper, KM | 1 |
Knapp, DJ | 2 |
Park, MA | 1 |
Breese, GR | 2 |
Fleming, W | 1 |
Jones, Q | 1 |
Chandra, U | 1 |
Saini, A | 1 |
Walker, D | 1 |
Francis, R | 1 |
Ocampo, G | 1 |
Kuhn, C | 1 |
Jacobskind, JS | 1 |
Rosinger, ZJ | 1 |
Brooks, ML | 1 |
Zuloaga, DG | 1 |
Martínez-Laorden, E | 2 |
Navarro-Zaragoza, J | 3 |
Milanés, MV | 14 |
Laorden, ML | 12 |
Almela, P | 3 |
Sharrett-Field, L | 1 |
Butler, TR | 2 |
Berry, JN | 2 |
Reynolds, AR | 2 |
Prendergast, MA | 4 |
Zhou, Y | 7 |
Leri, F | 2 |
Ho, A | 4 |
Kreek, MJ | 7 |
Sharrett-Field, LJ | 1 |
Pauly, JR | 1 |
Keller, CM | 1 |
Cornett, EM | 1 |
Guerin, GF | 1 |
Goeders, NE | 1 |
Hamilton, KL | 1 |
Harris, AC | 1 |
Gewirtz, JC | 1 |
Zanos, P | 3 |
Georgiou, P | 3 |
Wright, SR | 1 |
Hourani, SM | 1 |
Kitchen, I | 3 |
Winsky-Sommerer, R | 1 |
Bailey, A | 3 |
Ueno, K | 1 |
Kiguchi, N | 1 |
Kobayashi, Y | 1 |
Saika, F | 1 |
Wakida, N | 1 |
Yamamoto, C | 1 |
Maeda, T | 1 |
Ozaki, M | 1 |
Kishioka, S | 6 |
Abe, K | 1 |
Kobayashi, K | 1 |
Yoshino, S | 1 |
Taguchi, K | 1 |
Nojima, H | 1 |
Doremus-Fitzwater, TL | 1 |
Buck, HM | 2 |
Bordner, K | 1 |
Richey, L | 1 |
Jones, ME | 1 |
Deak, T | 2 |
Tanchuck-Nipper, MA | 1 |
Ford, MM | 1 |
Hertzberg, A | 1 |
Beadles-Bohling, A | 1 |
Cozzoli, DK | 1 |
Finn, DA | 5 |
Zhao, Z | 1 |
Lee, BH | 1 |
Lin, F | 1 |
Guo, Y | 1 |
Wu, Y | 1 |
In, S | 1 |
Park, SM | 1 |
Chan Kim, S | 1 |
Yang, CH | 1 |
Zhao, R | 1 |
Varani, AP | 1 |
Pedrón, VT | 1 |
Machado, LM | 1 |
Antonelli, MC | 1 |
Bettler, B | 1 |
Balerio, GN | 1 |
Wilhelm, CJ | 1 |
Hashimoto, JG | 1 |
Roberts, ML | 1 |
Bloom, SH | 1 |
Beard, DK | 1 |
Wiren, KM | 2 |
Schneider, R | 1 |
Santos, CF | 1 |
Clarimundo, V | 1 |
Dalmaz, C | 1 |
Elisabetsky, E | 1 |
Gomez, R | 1 |
García-Carmona, JA | 3 |
Baroja-Mazo, A | 1 |
Caffino, L | 1 |
Giannotti, G | 1 |
Malpighi, C | 1 |
Racagni, G | 1 |
Fumagalli, F | 1 |
Saunders, MA | 1 |
Brewton, HW | 1 |
Winchester, SR | 1 |
Elgumati, IS | 1 |
Dominguez, G | 1 |
Belzung, C | 1 |
Pierard, C | 1 |
David, V | 1 |
Henkous, N | 1 |
Decorte, L | 1 |
Mons, N | 1 |
Beracochea, D | 1 |
Hourani, S | 2 |
Scholl, JL | 1 |
Tu, W | 1 |
Watt, MJ | 1 |
Renner, KJ | 2 |
Bagosi, Z | 1 |
Palotai, M | 1 |
Simon, B | 1 |
Bokor, P | 1 |
Buzás, A | 1 |
Balangó, B | 1 |
Pintér, D | 1 |
Jászberényi, M | 1 |
Csabafi, K | 1 |
Szabó, G | 1 |
Kato, H | 1 |
Tsuji, M | 1 |
Miyagawa, K | 1 |
Takeda, K | 1 |
Takeda, H | 1 |
Ligeiro de Oliveira, AP | 1 |
Lazzarini, R | 1 |
Cavriani, G | 1 |
Quinteiro-Filho, WM | 1 |
Tavares de Lima, W | 1 |
Palermo-Neto, J | 1 |
Kubera, M | 1 |
Filip, M | 1 |
Budziszewska, B | 2 |
Basta-Kaim, A | 1 |
Wydra, K | 1 |
Leskiewicz, M | 1 |
Regulska, M | 1 |
Jaworska-Feil, L | 2 |
Przegalinski, E | 1 |
Machowska, A | 1 |
Lason, W | 2 |
Brooks, SP | 1 |
Croft, AP | 1 |
Norman, G | 1 |
Shaw, SG | 1 |
Little, HJ | 2 |
Alves, CJ | 1 |
Magalhães, A | 1 |
Summavielle, T | 1 |
Melo, P | 1 |
De Sousa, L | 1 |
Tavares, MA | 1 |
Monteiro, PR | 1 |
Hodgson, SR | 1 |
Hofford, RS | 1 |
Norris, CJ | 1 |
Eitan, S | 1 |
Núñez, C | 2 |
Földes, A | 1 |
Pérez-Flores, D | 1 |
García-Borrón, JC | 1 |
Kovács, KJ | 1 |
Rabbani, M | 2 |
Hajhashemi, V | 2 |
Mesripour, A | 1 |
Strong, MN | 1 |
Kaufman, KR | 1 |
Crabbe, JC | 5 |
Silva, SM | 2 |
Santos-Marques, MJ | 1 |
Madeira, MD | 3 |
Barr, JL | 1 |
Maiya, R | 1 |
Norris, EH | 1 |
Strickland, S | 1 |
Goeldner, C | 1 |
Lutz, PE | 1 |
Darcq, E | 1 |
Halter, T | 1 |
Clesse, D | 1 |
Ouagazzal, AM | 1 |
Kieffer, BL | 1 |
Whitman, BA | 1 |
Wills, TA | 1 |
Angel, RA | 1 |
Overstreet, DH | 1 |
Criswell, HE | 1 |
Ming, Z | 1 |
Aydin, C | 1 |
Oztan, O | 1 |
Isgor, C | 1 |
Hueston, CM | 1 |
Bishop, C | 1 |
Kupferschmidt, DA | 1 |
Newman, AE | 1 |
Boonstra, R | 1 |
Erb, S | 1 |
Thiel, KJ | 1 |
Painter, MR | 1 |
Pentkowski, NS | 1 |
Mitroi, D | 1 |
Crawford, CA | 1 |
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Carrasco, GA | 1 |
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Tanchuck, MA | 2 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
The Effect of N-acetylcysteine (NAC) on Treatment of Alcohol and Cocaine Use Disorders: A Double-Blind Randomized Controlled Trial.[NCT03018236] | Phase 4 | 100 participants (Anticipated) | Interventional | 2017-01-31 | Recruiting | ||
A Pilot Study of N-acetylcysteine for Alcohol Use Disorder[NCT04964843] | Phase 2 | 0 participants (Actual) | Interventional | 2023-04-30 | Withdrawn (stopped due to Null results were posted from a neurometabolite study and a recent trial for AUD. Study may resume if more positive data emerge.) | ||
PT150 (Formerly ORG34517) as a Potential Treatment for Alcohol Dependence-Alcohol Interaction Study[NCT03548714] | Phase 1 | 10 participants (Actual) | Interventional | 2018-09-01 | Completed | ||
The Efficiency of Eye Movement Desensitization and Reprocessing (EMDR) for the Treatment of Substance Use Disorders: A Randomized Controlled Trial[NCT03114423] | 60 participants (Anticipated) | Interventional | 2017-04-07 | Recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
1 review available for corticosterone and Drug Withdrawal Symptoms
Article | Year |
---|---|
Substance use disorders in patients with posttraumatic stress disorder: a review of the literature.
Topics: Adult; Animals; Arousal; Comorbidity; Corticosterone; Corticotropin-Releasing Hormone; Diagnosis, Du | 2001 |
153 other studies available for corticosterone and Drug Withdrawal Symptoms
Article | Year |
---|---|
HPA axis dysfunction during morphine withdrawal in offspring of female rats exposed to opioids preconception.
Topics: Analgesics, Opioid; Animals; Corticosterone; Corticotropin-Releasing Hormone; Female; Hypothalamo-Hy | 2022 |
Anxiety-like Behavior and GABAAR/BDZ Binding Site Response to Progesterone Withdrawal in a Stress-Vulnerable Strain, the Wistar Kyoto Rats.
Topics: Animals; Anxiety; Behavior, Animal; Binding Sites; Corticosterone; Diazepam; Female; Flunitrazepam; | 2022 |
Alcohol self-administration and nicotine withdrawal alter biomarkers of stress and inflammation and prefrontal cortex changes in Gβ subunits.
Topics: Animals; Corticosterone; Ethanol; Leptin; Male; Nicotine; Prefrontal Cortex; Rats; Rats, Wistar; Sub | 2023 |
Corticosterone in the ventral hippocampus differentially alters accumbal dopamine output in drug-naïve and amphetamine-withdrawn rats.
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Corticosterone; Dopamine; Hippocampus; Male | 2020 |
Combined cocaine and clonazepam administration induces REM sleep loss and anxiety-like withdrawal behaviors in rats.
Topics: Animals; Anxiety; Behavior, Animal; Clonazepam; Cocaine; Corticosterone; Exploratory Behavior; Male; | 2020 |
Hydrogen-rich saline attenuates anxiety-like behaviors in morphine-withdrawn mice.
Topics: Adaptation, Ocular; Animals; Anti-Anxiety Agents; Anxiety; Corticosterone; Disease Models, Animal; D | 2017 |
Abstinence from prolonged ethanol exposure affects plasma corticosterone, glucocorticoid receptor signaling and stress-related behaviors.
Topics: Alcohol Drinking; Alcoholism; Animals; Corticosterone; Disease Models, Animal; Ethanol; Hypothalamo- | 2017 |
Preclinical evaluation of the kappa-opioid receptor antagonist CERC-501 as a candidate therapeutic for alcohol use disorders.
Topics: Alcohol Deterrents; Alcoholism; Animals; Anxiety; Benzamides; Central Nervous System Depressants; Co | 2018 |
Differential effects of single versus repeated minocycline administration-Lack of significant interaction with chronic alcohol history.
Topics: Alcoholism; Amygdala; Animals; Anti-Bacterial Agents; Anxiety; Chemokine CCL2; Corticosterone; Drug | 2018 |
Withdrawal from Brief Repeated Alcohol Treatment in Adolescent and Adult Male and Female Rats.
Topics: Aging; Animals; Behavior, Animal; Blood Alcohol Content; Corticosterone; Drug Tolerance; Ethanol; Fe | 2019 |
Stress-induced neural activation is altered during early withdrawal from chronic methamphetamine.
Topics: Animals; Anxiety; Brain; CA3 Region, Hippocampal; Central Nervous System Stimulants; Corticosterone; | 2019 |
Conditioned aversive memory associated with morphine withdrawal increases brain-derived neurotrophic factor in dentate gyrus and basolateral amygdala.
Topics: Affect; Analgesics, Opioid; Animals; Basolateral Nuclear Complex; Brain-Derived Neurotrophic Factor; | 2020 |
Mifepristone pretreatment reduces ethanol withdrawal severity in vivo.
Topics: Alcoholism; Animals; Body Weight; Corticosterone; Drug Evaluation, Preclinical; Eating; Ethanol; Hor | 2013 |
Suppression of hypothalamic-pituitary-adrenal axis by acute heroin challenge in rats during acute and chronic withdrawal from chronic heroin administration.
Topics: Acute Disease; Adrenocorticotropic Hormone; Animals; Chronic Disease; Corticosterone; Heroin; Hypoth | 2013 |
Long-term ethanol and corticosterone co-exposure sensitize the hippocampal ca1 region pyramidal cells to insult during ethanol withdrawal in an NMDA GluN2B subunit-dependent manner.
Topics: Animals; CA1 Region, Hippocampal; Corticosterone; Ethanol; Female; Male; Organ Culture Techniques; P | 2013 |
Combinations of oxazepam and metyrapone attenuate cocaine and methamphetamine cue reactivity.
Topics: Amphetamine-Related Disorders; Analysis of Variance; Animals; Central Nervous System Stimulants; Coc | 2013 |
Affective and neuroendocrine effects of withdrawal from chronic, long-acting opiate administration.
Topics: Affect; Animals; Corticosterone; Male; Methadyl Acetate; Naloxone; Narcotic Antagonists; Narcotics; | 2013 |
The oxytocin analogue carbetocin prevents emotional impairment and stress-induced reinstatement of opioid-seeking in morphine-abstinent mice.
Topics: Affective Symptoms; Analysis of Variance; Animals; Brain; Corticosterone; Dose-Response Relationship | 2014 |
Possible involvement of endogenous opioid system located downstream of α7 nicotinic acetylcholine receptor in mice with physical dependence on nicotine.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Biomarkers; Corticosterone; Dose-Respon | 2014 |
Withdrawal of repeated morphine enhances histamine-induced scratching responses in mice.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Corticosterone; Dose-Response Relationship, Drug; His | 2015 |
Intoxication- and withdrawal-dependent expression of central and peripheral cytokines following initial ethanol exposure.
Topics: Age Factors; Alcoholic Intoxication; Animals; Brain; Corticosterone; Drug Tolerance; Ethanol; Interl | 2014 |
Sex Differences in Ethanol's Anxiolytic Effect and Chronic Ethanol Withdrawal Severity in Mice with a Null Mutation of the 5α-Reductase Type 1 Gene.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Alcohol Drinking; Animals; Anti-Anxiety Agents; Behavior, Ani | 2015 |
Effects of acupuncture at Zu-San-Li (ST36) on the activity of the hypothalamic--pituitary--adrenal axis during ethanol withdrawal in rats.
Topics: Acupuncture Points; Acupuncture Therapy; Adrenocorticotropic Hormone; Animals; Corticosterone; Corti | 2014 |
Lack of GABAB receptors modifies behavioural and biochemical alterations induced by precipitated nicotine withdrawal.
Topics: Animals; Anxiety; Brain; Brain-Derived Neurotrophic Factor; Corticosterone; Disease Models, Animal; | 2015 |
Persistent increases in rat hypothalamic POMC gene expression following chronic withdrawal from chronic "binge" pattern escalating-dose, but not steady-dose, cocaine.
Topics: Amygdala; Animals; Body Weight; Cocaine; Cocaine-Related Disorders; Corticosterone; Dopamine Uptake | 2015 |
Females uniquely vulnerable to alcohol-induced neurotoxicity show altered glucocorticoid signaling.
Topics: Alcoholism; Animals; Cell Death; Corticosterone; Ethanol; Female; Gene Expression; Glucocorticoids; | 2015 |
N-acetylcysteine prevents behavioral and biochemical changes induced by alcohol cessation in rats.
Topics: Acetylcysteine; Animals; Anxiety; Behavior, Animal; Central Nervous System Depressants; Corticostero | 2015 |
N-acetylcysteine prevents behavioral and biochemical changes induced by alcohol cessation in rats.
Topics: Acetylcysteine; Animals; Anxiety; Behavior, Animal; Central Nervous System Depressants; Corticostero | 2015 |
N-acetylcysteine prevents behavioral and biochemical changes induced by alcohol cessation in rats.
Topics: Acetylcysteine; Animals; Anxiety; Behavior, Animal; Central Nervous System Depressants; Corticostero | 2015 |
N-acetylcysteine prevents behavioral and biochemical changes induced by alcohol cessation in rats.
Topics: Acetylcysteine; Animals; Anxiety; Behavior, Animal; Central Nervous System Depressants; Corticostero | 2015 |
Sex differences between CRF1 receptor deficient mice following naloxone-precipitated morphine withdrawal in a conditioned place aversion paradigm: implication of HPA axis.
Topics: Adrenocorticotropic Hormone; Animals; Body Weight; Corticosterone; Female; Genotype; Hypothalamo-Hyp | 2015 |
Short-term withdrawal from developmental exposure to cocaine activates the glucocorticoid receptor and alters spine dynamics.
Topics: Animals; Cocaine; Corticosterone; Dendritic Spines; Disease Models, Animal; Dopamine Uptake Inhibito | 2015 |
Acute oral administration of the novel, competitive and selective glucocorticoid receptor antagonist ORG 34517 reduces the severity of ethanol withdrawal and related hypothalamic-pituitary-adrenal axis activation.
Topics: Administration, Oral; Alcohol Drinking; Alcoholism; Animals; Benzodioxoles; Corticosterone; Ethanol; | 2015 |
Alcohol withdrawal induces long-lasting spatial working memory impairments: relationship with changes in corticosterone response in the prefrontal cortex.
Topics: Alcoholism; Animals; Behavior, Animal; Corticosterone; Disease Models, Animal; Hippocampus; Male; Me | 2017 |
Methamphetamine abstinence induces changes in μ-opioid receptor, oxytocin and CRF systems: Association with an anxiogenic phenotype.
Topics: Amphetamine-Related Disorders; Amygdala; Animals; Anxiety; Central Nervous System Stimulants; Corpus | 2016 |
Amphetamine withdrawal differentially affects hippocampal and peripheral corticosterone levels in response to stress.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Amphetamine; Animals; Carbohydrate Dehydrogenases; Cent | 2016 |
Cocaine abstinence induces emotional impairment and brain region-specific upregulation of the oxytocin receptor binding.
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Corticosterone; Emotions; Hypothalamo | 2016 |
Selective CRF2 receptor agonists ameliorate the anxiety- and depression-like state developed during chronic nicotine treatment and consequent acute withdrawal in mice.
Topics: Animals; Anxiety; Corticosterone; Depression; Disease Models, Animal; Drug Evaluation, Preclinical; | 2016 |
Ethanol Withdrawal-Induced Impaired Recognition Is Reversed by Chronic Exposure to Stress and the Acute Administration of Corticosterone in Mice.
Topics: Alcoholism; Animals; Corticosterone; Ethanol; Male; Mice, Inbred ICR; Recognition, Psychology; Stres | 2016 |
Effects of single or repeated amphetamine treatment and withdrawal on lung allergic inflammation in rats.
Topics: Alveolitis, Extrinsic Allergic; Amphetamine; Animals; Antipsychotic Agents; Bone Marrow Cells; Bronc | 2008 |
Immunosuppression induced by a conditioned stimulus associated with cocaine self-administration.
Topics: Animals; Cell Proliferation; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corticostero | 2008 |
Nimodipine prior to alcohol withdrawal prevents memory deficits during the abstinence phase.
Topics: Alcohol-Induced Disorders; Alcohols; Analysis of Variance; Animals; Body Weight; Brain; Calcium Chan | 2008 |
Hormonal, neurochemical, and behavioral response to a forced swim test in adolescent rats throughout cocaine withdrawal.
Topics: Animals; Behavior, Animal; Cocaine; Corticosterone; Dopamine; Female; Humans; Male; Motor Activity; | 2008 |
Increased elevated plus maze open-arm time in mice during naloxone-precipitated morphine withdrawal.
Topics: Animals; Behavior, Animal; Corticosterone; Dose-Response Relationship, Drug; Male; Maze Learning; Mi | 2008 |
Elevated glucocorticoid levels are responsible for induction of tyrosine hydroxylase mRNA expression, phosphorylation, and enzyme activity in the nucleus of the solitary tract during morphine withdrawal.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Animals; Corticosterone; Hydrocortisone; Male; Morphine; | 2009 |
Increase in brain corticosterone concentration and recognition memory impairment following morphine withdrawal in mice.
Topics: Animals; Brain; Corticosterone; Male; Memory Disorders; Memory, Short-Term; Mice; Morphine; Naloxone | 2009 |
Sex differences in acute ethanol withdrawal severity after adrenalectomy and gonadectomy in Withdrawal Seizure-Prone and Withdrawal Seizure-Resistant mice.
Topics: Adrenal Glands; Adrenalectomy; Alcohol Withdrawal Seizures; Animals; Anticonvulsants; Corticosterone | 2009 |
Sexually dimorphic response of the hypothalamo-pituitary-adrenal axis to chronic alcohol consumption and withdrawal.
Topics: Alcohol-Induced Disorders, Nervous System; Alcoholism; Animals; Cell Death; Chronic Disease; Cortico | 2009 |
Effects of corticotropin-releasing factor receptor-1 antagonists on the brain stress system responses to morphine withdrawal.
Topics: Adrenocorticotropic Hormone; Animals; Brain; Brain Stem; Corticosterone; Iodine Radioisotopes; Male; | 2010 |
Withdrawal from chronic amphetamine produces persistent anxiety-like behavior but temporally-limited reductions in monoamines and neurogenesis in the adult rat dentate gyrus.
Topics: Amphetamine; Analysis of Variance; Animals; Anxiety; Cell Count; Cell Death; Corticosterone; Dentate | 2010 |
Involvement of tissue plasminogen activator in stress responsivity during acute cocaine withdrawal in mice.
Topics: Amygdala; Animals; Cocaine; Corticosterone; Corticotropin-Releasing Hormone; Hippocampus; Hypothalam | 2010 |
Impaired emotional-like behavior and serotonergic function during protracted abstinence from chronic morphine.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Disease Models, Animal; Drug Evaluation, Precl | 2011 |
Cytokine involvement in stress may depend on corticotrophin releasing factor to sensitize ethanol withdrawal anxiety.
Topics: Adaptation, Psychological; Alcohols; Amygdala; Analysis of Variance; Animals; Anxiety; Corticosteron | 2011 |
Effects of a selective Y2R antagonist, JNJ-31020028, on nicotine abstinence-related social anxiety-like behavior, neuropeptide Y and corticotropin releasing factor mRNA levels in the novelty-seeking phenotype.
Topics: Amygdala; Animals; Anxiety; Benzamides; CA3 Region, Hippocampal; Corticosterone; Corticotropin-Relea | 2011 |
Enhancement of the hypothalamic-pituitary-adrenal axis but not cytokine responses to stress challenges imposed during withdrawal from acute alcohol exposure in Sprague-Dawley rats.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Cytokines; Ethanol; Gene Expression Regulation | 2011 |
Antagonism of cannabinoid 1 receptors reverses the anxiety-like behavior induced by central injections of corticotropin-releasing factor and cocaine withdrawal.
Topics: Animals; Anxiety; Behavior, Animal; Cocaine; Corticosterone; Corticotropin-Releasing Hormone; Dopami | 2012 |
Environmental enrichment counters cocaine abstinence-induced stress and brain reactivity to cocaine cues but fails to prevent the incubation effect.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cocaine; Cocaine-Related Disorders; Conditioning, Operan | 2012 |
CRF2 receptor-deficiency eliminates opiate withdrawal distress without impairing stress coping.
Topics: Adaptation, Psychological; Animals; Behavior, Addictive; Brain; Corticosterone; Corticotropin-Releas | 2012 |
The role of social isolation in ethanol effects on the preweanling rat.
Topics: Analysis of Variance; Animals; Animals, Newborn; Central Nervous System Depressants; Corticosterone; | 2012 |
Effects of chronic alcohol consumption and withdrawal on the response of the male and female hypothalamic-pituitary-adrenal axis to acute immune stress.
Topics: Alcohol Drinking; Animals; Corticosterone; Corticotropin-Releasing Hormone; Disease Models, Animal; | 2012 |
Morphine withdrawal activates hypothalamic-pituitary-adrenal axis and heat shock protein 27 in the left ventricle: the role of extracellular signal-regulated kinase.
Topics: Adrenergic beta-Antagonists; Adrenocorticotropic Hormone; Aminoacetonitrile; Animals; Catechol O-Met | 2012 |
Influence of environmental enrichment on hypothalamic-pituitary-adrenal (HPA) responses to single-dose nicotine, continuous nicotine by osmotic mini-pumps, and nicotine withdrawal by mecamylamine in male and female rats.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Female; Hypothalamus; Male; Mecamylamine; Nico | 2012 |
Cocaine withdrawal causes delayed dysregulation of stress genes in the hippocampus.
Topics: Animals; Cocaine; Corticosterone; Gene Expression Regulation; Hippocampus; In Situ Hybridization; Ma | 2012 |
The effect of nimodipine on memory impairment during spontaneous morphine withdrawal in mice: Corticosterone interaction.
Topics: Animals; Brain; Calcium Channel Blockers; Corticosterone; Male; Memory Disorders; Mice; Morphine; Ni | 2012 |
Role of corticotropin-releasing factor (CRF) receptor-1 on the catecholaminergic response to morphine withdrawal in the nucleus accumbens (NAc).
Topics: Animals; Corticosterone; Dopamine; Male; Morphine; Morphine Dependence; Naloxone; Neurons; Norepinep | 2012 |
Prenatal opiate withdrawal activates the chick embryo hypothalamic pituitary-adrenal axis and dilates vitelline blood vessels via serotonin(2) receptors.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Chick Embryo; Corticosterone; Disease Models, Animal; Hypothal | 2002 |
Inhibition of protein kinase C but not protein kinase A attenuates morphine withdrawal excitation of rat hypothalamus-pituitary-adrenal axis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analgesics, Opioid; Animals; Blood-Brain Barrier; Catecholamines; Ch | 2002 |
Alterations in hypothalamic-pituitary-adrenal axis activity and in levels of proopiomelanocortin and corticotropin-releasing hormone-receptor 1 mRNAs in the pituitary and hypothalamus of the rat during chronic 'binge' cocaine and withdrawal.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Amygdala; Animals; Blotting, Northern; Cocaine; Cortico | 2003 |
Amphetamine withdrawal does not produce a depressive-like state in rats as measured by three behavioral tests.
Topics: Adrenocorticotropic Hormone; Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulan | 2003 |
Behavioural and gene transcription alterations induced by spontaneous cannabinoid withdrawal in mice.
Topics: Animals; Autoradiography; Behavior, Animal; Benzoxazines; Binding, Competitive; Body Temperature; Br | 2003 |
Reduced social interaction following 3,4-methylenedioxymethamphetamine is not associated with enhanced 5-HT 2C receptor responsivity.
Topics: Animals; Brain; Corticosterone; Exploratory Behavior; Hydroxyindoleacetic Acid; Hypothermia; In Vitr | 2003 |
Stress-induced suppression of the immune system after withdrawal from chronic cocaine.
Topics: Adrenalectomy; Animals; Cell Division; Cocaine; Corticosterone; Disease Models, Animal; Dopamine Upt | 2003 |
Increased CRH mRNA levels in the rat amygdala during short-term withdrawal from chronic 'binge' cocaine.
Topics: Amygdala; Animals; Brain Stem; Chronic Disease; Cocaine; Cocaine-Related Disorders; Corticosterone; | 2003 |
Nicotine withdrawal induces subsensitivity of hypothalamic-pituitary-adrenal axis to stress in rats: implications for precipitation of depression during smoking cessation.
Topics: Adaptation, Physiological; Adrenal Cortex Function Tests; Animals; Corticosterone; Depression; Dexam | 2004 |
Immune cell activity during the initial stages of withdrawal from chronic exposure to cocaine or morphine.
Topics: Analysis of Variance; Animals; Cocaine; Concanavalin A; Corticosterone; Lymphocytes; Male; Mitogens; | 2004 |
Anxiolytic-like effects of the corticotropin-releasing factor1 (CRF1) antagonist DMP904 [4-(3-pentylamino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)-pyrazolo-[1,5-a]-pyrimidine] administered acutely or chronically at doses occupying central CRF1 receptors
Topics: Animals; Anti-Anxiety Agents; Anxiety; Chlordiazepoxide; Corticosterone; Discrimination Learning; Ma | 2004 |
Behavioral and molecular changes elicited by acute administration of SR141716 to Delta9-tetrahydrocannabinol-tolerant rats: an experimental model of cannabinoid abstinence.
Topics: Animals; Arachidonic Acids; Behavior, Animal; Brain; Cannabinoid Receptor Antagonists; Cannabinoid R | 2004 |
Evidence for alterations in alpha2-adrenergic receptor sensitivity in rats exposed to repeated cocaine administration.
Topics: Adrenergic alpha-Agonists; Animals; Brain; Clonidine; Cocaine; Cocaine-Related Disorders; Corticoste | 2004 |
Suppressed fever and hypersensitivity responses in chicks prenatally exposed to opiates.
Topics: Analysis of Variance; Animals; Basophils; Chick Embryo; Chickens; Corticosterone; Disease Models, An | 2004 |
Spontaneous withdrawal from the triazolobenzodiazepine alprazolam increases cortical corticotropin-releasing factor mRNA expression.
Topics: Adrenocorticotropic Hormone; Alprazolam; Animals; Anti-Anxiety Agents; Autoradiography; Body Weight; | 2004 |
Electroacupuncture attenuates morphine withdrawal signs and c-Fos expression in the central nucleus of the amygdala in freely moving rats.
Topics: Amygdala; Analysis of Variance; Animals; Behavior, Animal; Cell Count; Corticosterone; Electroacupun | 2005 |
Corticosterone increases damage and cytosolic calcium accumulation associated with ethanol withdrawal in rat hippocampal slice cultures.
Topics: Animals; Calcium; Central Nervous System Depressants; Corticosterone; Cytosol; Ethanol; Female; Fluo | 2005 |
Morphine withdrawal contributes to Th cell differentiation by biasing cells toward the Th2 lineage.
Topics: Active Transport, Cell Nucleus; Animals; Cell Differentiation; Cell Lineage; Cells, Cultured; Cortic | 2005 |
Previous experience of ethanol withdrawal increases withdrawal-induced c-fos expression in limbic areas, but not withdrawal-induced anxiety and prevents withdrawal-induced elevations in plasma corticosterone.
Topics: Animals; Anxiety; Corticosterone; Early Growth Response Protein 1; Ethanol; Limbic System; Male; Maz | 2006 |
Sex differences in steroid modulation of ethanol withdrawal in male and female rats.
Topics: Animals; Corticosterone; Estradiol; Ethanol; Female; Male; Neuroprotective Agents; Ovariectomy; Pent | 2007 |
Cocaine-mediated supersensitivity of 5-HT2A receptors in hypothalamic paraventricular nucleus is a withdrawal-induced phenomenon.
Topics: Amphetamines; Animals; Blotting, Western; Cocaine; Corticosterone; Dopamine Uptake Inhibitors; Drug | 2006 |
Mu opioid receptor and orexin/hypocretin mRNA levels in the lateral hypothalamus and striatum are enhanced by morphine withdrawal.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Gene Expression; Hypothalamic Area, Lateral; I | 2006 |
Restraint-induced corticosterone secretion and hypothalamic CRH mRNA expression are augmented during acute withdrawal from chronic cocaine administration.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Corticosterone; Corticotropin-Releasing Hormone; Dopami | 2007 |
Disruption of the CRF/CRF1 receptor stress system exacerbates the somatic signs of opiate withdrawal.
Topics: Analysis of Variance; Animals; Behavior, Animal; Corticosterone; Corticotropin-Releasing Hormone; Di | 2007 |
Sex differences in the effect of finasteride on acute ethanol withdrawal severity in C57BL/6J and DBA/2J mice.
Topics: Acute Disease; Animals; Central Nervous System Depressants; Corticosterone; Data Interpretation, Sta | 2007 |
Involvement of arginine vasopressin and V1b receptor in heroin withdrawal and heroin seeking precipitated by stress and by heroin.
Topics: Adrenocorticotropic Hormone; Animals; Arginine Vasopressin; Corticosterone; Exploratory Behavior; He | 2008 |
The impact of gonadectomy and adrenalectomy on acute withdrawal severity in male and female C57BL/6J and DBA/2J mice following a single high dose of ethanol.
Topics: Animals; Central Nervous System Depressants; Corticosterone; Dose-Response Relationship, Drug; Estra | 2007 |
Decreased anticonvulsant efficacy of allopregnanolone during ethanol withdrawal in female Withdrawal Seizure-Prone vs. Withdrawal Seizure-Resistant mice.
Topics: Animals; Anticonvulsants; Central Nervous System Depressants; Corticosterone; Estradiol; Ethanol; Fe | 2008 |
L-type calcium channel blockade attenuates morphine withdrawal: in vivo interaction between L-type calcium channels and corticosterone.
Topics: Adrenalectomy; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Corticosterone; Drug Int | 2008 |
Disruption of the CRF(2) receptor pathway decreases the somatic expression of opiate withdrawal.
Topics: Animals; Brain; Brain Chemistry; Corticosterone; Disease Models, Animal; Down-Regulation; Female; Ge | 2008 |
Chronic ethanol exposure leads to divergent control of dopaminergic synapses in distinct target regions.
Topics: Animals; Biogenic Monoamines; Blotting, Western; Brain Chemistry; Central Nervous System Depressants | 2008 |
Some responses of the immature fowl to the withdrawal of a stressor.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Animals, Newborn; Body Weight; Chickens; Chole | 1980 |
Ethanol dependence and the pituitary adrenal axis in mice. II. Temporal analysis of dependence and withdrawal.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Alcoholism; Animals; beta-Endorphin; Corticosterone; En | 1983 |
Effect of naloxone administration upon responses of adrenal hormones to withdrawal from ethanol.
Topics: Adrenal Cortex; Adrenal Medulla; Animals; Catecholamines; Corticosterone; Dopamine; Epinephrine; Eth | 1984 |
Further studies on the acute dependence produced by morphine in opiate naive rats.
Topics: Amphetamine; Animals; Corticosterone; Diazepam; Drug Tolerance; Humans; Male; Morphine; Morphine Dep | 1982 |
Effects of naloxone on plasma corticosterone in the opiate-naive rat.
Topics: Animals; Corticosterone; Humans; Levorphanol; Male; Morphine; Naloxone; Narcotics; Rats; Substance W | 1980 |
Inhibition of rat brain tryptophan metabolism by ethanol withdrawal and possible involvement of the enhanced liver tryptophan pyrrolase activity.
Topics: Animals; Behavior, Animal; Brain; Corticosterone; Ethanol; Humans; Liver; Male; NAD; Rats; Serotonin | 1980 |
The effects of ethanol on rat liver and brain tryptophan metabolism.
Topics: Alcoholism; Animals; Brain Chemistry; Corticosterone; Ethanol; Humans; Liver; Male; Rats; Rats, Inbr | 1980 |
Evidence for alterations in presynaptic serotonergic function during withdrawal from chronic cocaine in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Cocaine; Corticosterone; Fenfluramine | 1995 |
Corticosterone increases severity of acute withdrawal from ethanol, pentobarbital, and diazepam in mice.
Topics: Animals; Behavior, Animal; Corticosterone; Diazepam; Ethanol; Female; Flumazenil; Handling, Psycholo | 1994 |
Quantitative properties of plasma corticosterone elevation induced by naloxone-precipitated withdrawal in morphine-dependent rats.
Topics: Analysis of Variance; Animals; Body Weight; Corticosterone; Disease Models, Animal; Dose-Response Re | 1994 |
Immobilization stress-induced oral opioid self-administration and withdrawal in rats: role of conditioning factors and the effect of stress on "relapse" to opioid drugs.
Topics: Animals; Conditioning, Psychological; Corticosterone; Fentanyl; Immobilization; Male; Morphine; Morp | 1993 |
Effects of intracerebroventricular clonidine on the hypothalamic noradrenaline and plasma corticosterone levels of opiate naive rats and after naloxone-induced withdrawal.
Topics: Animals; Clonidine; Corticosterone; Hypothalamus; Injections, Intraventricular; Male; Morphine Depen | 1994 |
Modulation by catecholamine of hypothalamus-pituitary-adrenocortical (HPA) axis activity in morphine-tolerance and withdrawal.
Topics: Animals; Corticosterone; Dopamine; Drug Implants; Drug Tolerance; Hypothalamo-Hypophyseal System; Ma | 1994 |
Modification of behavioral effects of 8-hydroxy-2-(di-n-propylamino)tetralin following chronic ethanol consumption in the rat: evidence for the involvement of 5-HT1A receptors in ethanol dependence.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Corticosterone; Dose-Response Rel | 1995 |
No relation of plasma morphine level to the severity of naloxone-induced withdrawal in acute morphine-dependent rats.
Topics: Animals; Body Weight; Corticosterone; Dose-Response Relationship, Drug; Male; Morphine; Naloxone; Ra | 1995 |
Neurosteroids and the naloxone-precipitated withdrawal syndrome in morphine-dependent mice.
Topics: 5-alpha-Dihydroprogesterone; Animals; Behavior, Animal; Corticosterone; Dehydroepiandrosterone; Deso | 1996 |
Possible involvement of the total amount of morphine infused in the development of acute morphine dependence in rats.
Topics: Acute Disease; Analysis of Variance; Animals; Corticosterone; Diarrhea; Infusions, Intravenous; Male | 1996 |
Chronic naloxone-induced supersensitivity affects neither tolerance to nor physical dependence on morphine at hypothalamus-pituitary-adrenocortical axis.
Topics: Animals; Behavior, Animal; Corticosterone; Drug Tolerance; Hypothalamo-Hypophyseal System; Male; Mor | 1996 |
Diltiazem inhibits naloxone-precipitated and spontaneous morphine withdrawal in rats.
Topics: Animals; Body Weight; Calcium Channel Blockers; Corticosterone; Diarrhea; Diltiazem; Drug Interactio | 1996 |
Chronic alcohol consumption and withdrawal do not induce cell death in the suprachiasmatic nucleus, but lead to irreversible depression of peptide immunoreactivity and mRNA levels.
Topics: Alcohol Drinking; Animals; Astrocytes; Body Weight; Brain; Cell Death; Corticosterone; Ethanol; Male | 1997 |
Activation of corticotropin-releasing factor in the limbic system during cannabinoid withdrawal.
Topics: Amygdala; Animals; Anxiety; Behavior, Animal; Brain; Corticosterone; Corticotropin-Releasing Hormone | 1997 |
Sex differences in effects of predictable and unpredictable footshock on fentanyl self-administration in rats.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Conditioning, Operant; Corticosterone; Electroshock; | 1997 |
Gluconeogenic activity in response to chronic administration of amphetamine sulphate and drug withdrawal.
Topics: Adrenocorticotropic Hormone; Alanine Transaminase; Amphetamine; Animals; Aspartate Aminotransferases | 1997 |
Increased motor response to cocaine administration following recovery from chronic corticosterone treatment in the rat.
Topics: Animals; Cocaine; Corticosterone; Dopamine Uptake Inhibitors; Male; Motor Activity; Rats; Rats, Wist | 1998 |
Stress-induced cross-sensitization to cocaine: effect of adrenalectomy and corticosterone after short- and long-term withdrawal.
Topics: Adrenalectomy; Animals; Cocaine; Corticosterone; Dopamine Uptake Inhibitors; Environment; Male; Moto | 1998 |
Alterations in corticotropin-releasing factor and vasopressin content in rat brain during morphine withdrawal: correlation with hypothalamic noradrenergic activity and pituitary-adrenal response.
Topics: Animals; Arginine Vasopressin; Brain Chemistry; Corticosterone; Corticotropin-Releasing Hormone; Hyp | 1998 |
Time course of morphine withdrawal and preproenkephalin gene expression in the periaqueductal gray of rats.
Topics: Animals; Body Weight; Corticosterone; Enkephalins; Gene Expression Regulation; Injections, Subcutane | 1998 |
Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1.
Topics: Adrenocorticotropic Hormone; Animals; Anxiety; Cells, Cultured; Corticosterone; Ethanol; In Situ Hyb | 1998 |
Changes in right atrial catecholamine content in naïve rats and after naloxone-induced withdrawal.
Topics: Animals; Catecholamines; Corticosterone; Drug Administration Schedule; Drug Tolerance; Heart Atria; | 1998 |
Lack of sex differences in anxiety behaviors during precipitated benzodiazepine withdrawal in rats.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Corticosterone; Diazepam; Estradiol; Female; Flumazenil; GABA | 1999 |
Noradrenergic and dopaminergic activity in the hypothalamic paraventricular nucleus after naloxone-induced morphine withdrawal.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Behavior, Animal; Body Weight; Chroni | 2000 |
Effects of U-50,488H and U-50,488H withdrawal on catecholaminergic neurons of the rat hypothalamus.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; 3,4-Dihydr | 2000 |
The novel 5-Hydroxytryptamine(1A) antagonist LY426965: effects on nicotine withdrawal and interactions with fluoxetine.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Animals; Body Temperature; Columbidae; | 2000 |
Effects of adolescent nicotine exposure on opioid consumption and neuroendocrine responses in adult male and female rats.
Topics: Adrenocorticotropic Hormone; Aging; Analgesics, Opioid; Animals; Body Weight; Corticosterone; Drinki | 2001 |
Differential responsivity of the hypothalamic-pituitary-adrenal axis to glucocorticoid negative-feedback and corticotropin releasing hormone in rats undergoing morphine withdrawal: possible mechanisms involved in facilitated and attenuated stress response
Topics: Adrenocorticotropic Hormone; Analgesics, Opioid; Animals; Area Under Curve; Blotting, Western; Corti | 2001 |
Corticosterone concentrations in mice during ethanol drinking and withdrawal.
Topics: Alcoholism; Animals; Circadian Rhythm; Corticosterone; Ethanol; Humans; Male; Mice; Substance Withdr | 1978 |
Effects of nicotine administration and its withdrawal on plasma corticosterone and brain 5-hydroxyindoles.
Topics: Animals; Brain; Corticosterone; Hippocampus; Humans; Hydroxyindoleacetic Acid; Hypothalamus; Male; N | 1979 |
Brain catecholamines and ethanol: involvement in physical dependence and withdrawal.
Topics: Alcoholism; Animals; Body Temperature; Brain Chemistry; Corticosterone; Ethanol; Humans; Male; Motor | 1977 |
Alcohol intoxication and withdrawal in inbred strains of mice: behavioral and endocrine studies.
Topics: Alcoholic Intoxication; Alcoholism; Animals; Behavior, Animal; Corticosterone; Ethanol; Genotype; Hu | 1979 |
The involvement of corticosteroids in the supersensitivity produced in the rat anococcygeus muscle by morphine withdrawal, thyroidectomy or a single dose of reserpine.
Topics: Acetylcholine; Adrenalectomy; Animals; Body Weight; Corticosterone; Humans; In Vitro Techniques; Mal | 1975 |
Reduction in the cholinesterase activity of the rat anococcygeus muscle produced by corticosterone.
Topics: Adrenal Glands; Adrenalectomy; Animals; Cholinesterases; Corticosterone; Depression, Chemical; Human | 1975 |
Genetic differences in hypothalamic-pituitary-adrenal axis responsiveness to acute ethanol and acute ethanol withdrawal.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Ethanol; Handling, Psychological; Hypothalamo- | 1992 |
Role of the adrenal gland in the thermal response to morphine withdrawal in rats.
Topics: Adrenal Cortex; Adrenal Glands; Adrenal Medulla; Adrenalectomy; Animals; Body Temperature; Body Weig | 1992 |
Attenuation of the morphine withdrawal syndrome by inhibition of catabolism of endogenous enkephalins in the periaqueductal gray matter.
Topics: Analgesics; Animals; Behavior, Animal; Body Temperature; Body Weight; Corticosterone; Dipeptides; En | 1992 |
Effects of specific mu and kappa opiate tolerance and abstinence on hypothalamo-pituitary-adrenal axis secretion in the rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenocort | 1990 |
The effects of diazepam on brain 5-HT and 5-HIAA in stressed and unstressed rats.
Topics: Altitude; Animals; Brain; Cerebral Cortex; Corticosterone; Diazepam; Habituation, Psychophysiologic; | 1987 |
Effects of beta-carboline-ethyl ester on plasma corticosterone--a parallel with antagonist-precipitated diazepam withdrawal.
Topics: Animals; Behavior, Animal; Benzodiazepines; Carbolines; Corticosterone; Diazepam; Kinetics; Male; Py | 1989 |
Effects of withdrawal from chronic exposure to cigarette smoke on hypothalamic and preoptic catecholamine nerve terminal systems and on the secretion of pituitary hormones in the male rat.
Topics: Animals; Catecholamines; Corticosterone; Cotinine; Hypothalamus; Male; Nerve Endings; Nicotine; Nore | 1989 |
Comparison of selective and complete inhibitors of enkephalin-degrading enzymes on morphine withdrawal syndrome.
Topics: Animals; Behavior, Animal; Body Temperature; Body Weight; Corticosterone; Dipeptides; Hydroxamic Aci | 1989 |
Mianserin attenuates naloxone-precipitated withdrawal signs in rats acutely or chronically dependent upon morphine.
Topics: Animals; Body Temperature; Clonidine; Corticosterone; Dibenzazepines; Male; Mianserin; Morphine Depe | 1986 |
Central histaminergic stimulation of corticosterone and hyperlipemic responses after chronic ethanol consumption in rats.
Topics: Animals; Corticosterone; Ethanol; Fatty Acids, Nonesterified; Male; Pituitary-Adrenal System; Rats; | 1987 |
Diazepam withdrawal as demonstrated by changes in plasma corticosterone: a role for the hippocampus.
Topics: Animals; Cerebral Ventricles; Corticosterone; Diazepam; Drug Implants; Hippocampus; Male; Rats; Rats | 1987 |
Prolonged protective effects following propranolol withdrawal against isoproterenol-induced myocardial infarction in normotensive and hypertensive rats.
Topics: Animals; Blood Pressure; Corticosterone; Creatine Kinase; Female; Humans; Isoproterenol; L-Lactate D | 1985 |
Effects of chronic treatment with diazepam, phenobarbital, or amphetamine on naloxone-precipitated morphine withdrawal.
Topics: Amphetamine; Animals; Corticosterone; Diazepam; Male; Mice; Morphine Dependence; Motor Activity; Nal | 1985 |
[Dependence on central analgesics. 2. Relationship between alteration of the mitochondria of the zona fasciculata of the rat due to morphine dependence and corticosterone metabolism].
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Ascorbic Acid; Corticosterone; Depression, Che | 1971 |
Reversal of the action of morphine on the secretory activity of the adrenal cortex.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenal Glands; Animals; Birefringence; Cholesterol; Cortic | 1974 |
Adrenal glucocorticoids as a required factor in the development of ethanol withdrawal seizures in mice.
Topics: Adrenal Glands; Alcoholic Intoxication; Animals; Corticosterone; Humans; Male; Mice; Mice, Inbred St | 1974 |
Studies on the physical dependence liability of anlgesics. 2. Relationship between transformation of intramitochondrial structures in adrenocortical cells and corticosterone biosynthesis in morphine addicted rats.
Topics: Adrenal Glands; Animals; Ascorbic Acid; Corticosterone; Humans; Male; Mitochondria; Morphine Depende | 1973 |
Morphine analgesia, tolerance and physical dependence in the adrenalectomized rat.
Topics: Adrenal Glands; Adrenalectomy; Analgesia; Animals; Body Weight; Corticosterone; Drug Tolerance; Huma | 1973 |
Some endocrinological aspects of barbiturate dependence.
Topics: Adrenal Glands; Animals; Barbiturates; Body Weight; Corticosterone; Endocrine Glands; Female; Frustr | 1971 |