corticosterone has been researched along with Disease Models, Animal in 1767 studies
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study we have evaluated the MMP-9 activity and protein expression in brain areas relevant to depression using the chronic corticosterone mouse model of depression." | 8.31 | Brain matrix metalloproteinase-9 activity is altered in the corticosterone mouse model of depression. ( Breviario, S; Castro, E; Díaz, Á; Florensa-Zanuy, E; Garro-Martínez, E; Pazos, Á; Pilar-Cuéllar, F; Senserrich, J, 2023) |
| "Here, we employed mouse models of depression induced by chronic unpredictable stress exposure or corticosterone (CORT) stimulation." | 8.31 | MAD2B Blunts Chronic Unpredictable Stress and Corticosterone Stimulation-Induced Depression-Like Behaviors in Mice. ( Meng, X; Miao, C; Su, Y; Wang, XL; Zhang, C, 2023) |
| "Using 2 distinct animal models, this study shows that in mice, early life stress leads to reduced colonic corticosterone and that induction of colitis after stress removal results in reduced transcription of glucocorticoid synthesis genes, increased Tnf, and enhanced chronicity of intestinal inflammation." | 8.31 | Early Life Stress in Mice Leads to Impaired Colonic Corticosterone Production and Prolonged Inflammation Following Induction of Colitis. ( Alexander, KL; Foote, JB; Hsu, JS; Jennings, MS; Kellum, CE; Klocke, BJ; Lee, G; Lorenz, RG; Maynard, CL; Molina, PA; Muir, RQ; Pollock, JS, 2023) |
| " Metyrapone, an inhibitor of corticosterone synthesis, completely abolished seizures in GAERS, and seizures remained suppressed for >2 h." | 8.31 | Metyrapone abolishes spike-wave discharge seizures in genetic absence epilepsy rats from Strasbourg by reducing stress hormones. ( Dezsi, G; Harris, G; Jones, NC; O'Brien, TJ; Ozturk, E; Paul, C, 2023) |
| "Mirtazapine (MIRT) is a multi-target antidepressant used in treatment of severe depression with promising efficacy, but also with important side effects, mainly sedation and weight gain." | 8.12 | Lipoic acid prevents mirtazapine-induced weight gain in mice without impairs its antidepressant-like action in a neuroendocrine model of depression. ( Chaves Filho, AJM; Cunha, NL; De Oliveira, GMF; Gadelha Filho, CVJ; Jucá, PM; Macedo, DS; Oliveira, TQ; Soares, MVR; Vasconcelos, SMM; Viana, GA; Vieira, CFX, 2022) |
| "The aim of this study was to investigate the antidepressant effect of Jujuboside A (JuA) on corticosterone (CORT)-induced depression in mice and explore the underlying mechanisms." | 8.12 | Antidepressant effect of Jujuboside A on corticosterone-induced depression in mice. ( Gong, J; Li, H; Li, J; Xie, X; Zhang, T, 2022) |
| "Since 2012, studies in mice, rats, and humans have suggested that abnormalities in purinergic signaling may be a final common pathway for many genetic and environmental causes of autism spectrum disorder (ASD)." | 8.02 | Metabolic and behavioral features of acute hyperpurinergia and the maternal immune activation mouse model of autism spectrum disorder. ( Blake, DR; Hirsch, CM; Le, TP; Li, K; Meinardi, S; Monk, JM; Nakayama, T; Naviaux, JC; Naviaux, RK; Wang, L; Zolkipli-Cunningham, Z, 2021) |
| " In this study, using rat TBI model (lateral fluid percussion cortical injury), we assessed potential association of immediate posttraumatic seizures and changes in corticosterone (CS) levels with neuroinflammation and neuronal cell loss in the hippocampus." | 8.02 | Neuroinflammation and Neuronal Loss in the Hippocampus Are Associated with Immediate Posttraumatic Seizures and Corticosterone Elevation in Rats. ( Frankevich, SO; Gulyaeva, NV; Komoltsev, IG; Moiseeva, JV; Novikova, MR; Onufriev, MV; Shirobokova, NI; Volkova, AA, 2021) |
| " Our previous studies found that melatonin exerts an improvement effect in sleep deprivation (SD)- induced corticosterone overproduction and colitis." | 8.02 | Melatonin Ameliorates Corticosterone-Mediated Oxidative Stress-Induced Colitis in Sleep-Deprived Mice Involving Gut Microbiota. ( Cao, J; Chen, Y; Dong, Y; Gao, T; Wang, Z, 2021) |
| " Here we aimed to compare the effects of (R)-norketamine ((R)-NK), (S)-NK, (2R,6R)-HNK, and (2S,6S)-HNK in a mouse model of depression induced by chronic corticosterone (CORT) injection." | 7.96 | (S)-norketamine and (2S,6S)-hydroxynorketamine exert potent antidepressant-like effects in a chronic corticosterone-induced mouse model of depression. ( Ago, Y; Chen, L; Hashimoto, H; Hashimoto, K; Higuchi, M; Kasai, A; Naito, M; Nakagawa, S; Nakazawa, T; Seiriki, K; Tanabe, W; Tsukada, S; Yamaguchi, T; Yokoyama, R, 2020) |
| "As a continuation of our previous experiments, this study aimed to investigate the antidepressant- and anxiolytic-like activity of pitolisant in mice using the corticosterone-induced depression model." | 7.96 | Pitolisant protects mice chronically treated with corticosterone from some behavioral but not metabolic changes in corticosterone-induced depression model. ( Kieć-Kononowicz, K; Kotańska, M; Mika, K; Pytka, K; Sapa, J; Sałaciak, K; Wheeler, L, 2020) |
| " Considering that ketamine has significant knock-on effects, this study investigated the effects of a single coadministration with subthreshold doses of ketamine plus guanosine in a corticosterone (CORT)-induced animal model of depression and the role of anti-inflammatory and antioxidant pathways." | 7.96 | Subthreshold doses of guanosine plus ketamine elicit antidepressant-like effect in a mouse model of depression induced by corticosterone: Role of GR/NF-κB/IDO-1 signaling. ( B Zeni, AL; Camargo, A; Dalmagro, AP; M Rosa, J; P Kaster, M; S Rodrigues, AL; Tasca, CI, 2020) |
| "A total of 36 rats were randomly assigned to three groups: a normal group, model group (depression), and treatment group (depression + gentiopicroside)." | 7.91 | Metabolomic evidence for the therapeutic effect of gentiopicroside in a corticosterone-induced model of depression. ( Cui, Q; Liu, Z; Wang, C; Wang, G; Yao, T; Zhang, Q, 2019) |
| " A treatment with escitalopram reversed depression-like behavior accompanied by reductions in BDNF levels in serum and the nucleus accumbens, while a treatment with blonanserin ameliorated abnormal social interaction behavior with reductions in serum BDNF levels." | 7.91 | Antidepressant activities of escitalopram and blonanserin on prenatal and adolescent combined stress-induced depression model: Possible role of neurotrophic mechanism change in serum and nucleus accumbens. ( Deriha, K; Furuse, K; Hashiguchi, H; Hashimoto, E; Ishii, T; Kawanishi, C; Kigawa, Y; Shiraishi, M; Tayama, M; Ukai, W, 2019) |
| " This study utilized a translational animal model of maternal depression (based on giving high levels of corticosterone (CORT, 40 mg/kg, s." | 7.91 | Developmental outcomes after gestational antidepressant treatment with sertraline and its discontinuation in an animal model of maternal depression. ( Brummelte, S; Kott, JM; Mooney-Leber, SM, 2019) |
| " In this study, we examined the molecular effects associated with a response to a week-long treatment with escitalopram in the chronic escape deficit (CED) model, a validated model of depression based on the induction of an escape deficit after exposure of rats to an unavoidable stress." | 7.88 | Molecular changes associated with escitalopram response in a stress-based model of depression. ( Alboni, S; Benatti, C; Blom, JMC; Brunello, N; Mendlewicz, J; Tascedda, F, 2018) |
| "Many models, such as chronic mild stress, chronic stress or chronic corticosterone injections are used to induce depression associated with cognitive deficits." | 7.88 | Combined corticosterone treatment and chronic restraint stress lead to depression associated with early cognitive deficits in mice. ( Bahane, DAN; Bum, EN; Ngoupaye, GT; Yassi, FB, 2018) |
| " Magnolol, main constituent identified in the barks of Magnolia officinalis, exerted antidepressant effects in a rat model of depression induced by chronic unpredictable mild stress in previous studies." | 7.88 | Antidepressant effects of magnolol in a mouse model of depression induced by chronic corticosterone injection. ( Bai, Y; Dai, G; Jing, W; Ju, W; Song, L; Xu, M; Zhang, W; Zhu, L, 2018) |
| " Therefore, we tested this hypothesis in the depression model of chronic administration of corticosterone (CORT) in mice and treated the animals daily with liraglutide (5 or 20 nmol/kg ip." | 7.88 | Liraglutide attenuates the depressive- and anxiety-like behaviour in the corticosterone induced depression model via improving hippocampal neural plasticity. ( Birong, L; Christian, H; Feiyu, S; Le, W; Weina, H; Yuhu, N, 2018) |
| " We evaluated the acute corticosterone response to hypoxia or ACTH injection following pretreatment with GPS1574 (32 mg/kg) or vehicle for GPS1574 in PD2, PD8, and PD15 rat pups." | 7.88 | Effect of a melanocortin type 2 receptor (MC2R) antagonist on the corticosterone response to hypoxia and ACTH stimulation in the neonatal rat. ( Gehrand, AL; Goldenberg, AJ; Hoeynck, B; Jablonski, M; Raff, H; Waples, E, 2018) |
| " Ursolic acid, metformin, gliclazide and their combinations when administered daily for 30 days significantly improved insulin sensitivity apart from behavioral and biochemical alterations in stressed mice." | 7.88 | Synergistic action of ursolic acid and metformin in experimental model of insulin resistance and related behavioral alterations. ( Ahuja, S; Akhtar, A; Kumar, A; Mourya, A; Sah, SP, 2018) |
| " The corticosterone rat model was developed to understand the influence of stress on depression-like symptomatology." | 7.88 | Depression-like behaviors induced by chronic corticosterone exposure via drinking water: Time-course analysis. ( Cui, SY; Cui, XY; Ding, H; Hu, X; Liu, YT; Ye, H; Zhang, YH; Zhao, HL, 2018) |
| " This study aims to investigate the potential effects of hydrogen-rich saline (HRS) administration on naloxone-precipitated withdrawal symptoms and morphine withdrawal-induced anxiety-like behaviors." | 7.85 | Hydrogen-rich saline attenuates anxiety-like behaviors in morphine-withdrawn mice. ( Cong, B; Gong, M; Guo, H; Hui, R; Ma, C; Shen, Q; Wang, J; Wen, D; Zhao, P, 2017) |
| "To further explore the underlying antidepressant mechanism of ginseng total saponins (GTS), this study observed the effects on hippocampal astrocyte structural plasticity and hippocampal volume in the corticosterone-induced mouse depression model." | 7.85 | Preventive Effects of Ginseng Total Saponins on Chronic Corticosterone-Induced Impairment in Astrocyte Structural Plasticity and Hippocampal Atrophy. ( Chen, L; Dai, JG; Huang, YF; Lin, ZX; Wang, X; Zhao, YN, 2017) |
| " This investigation addressed the hypothesis that topical 5α-tetrahydrocorticosterone (5αTHB, a corticosterone metabolite) inhibits dermal inflammation without affecting processes responsible for skin thinning and impaired wound healing." | 7.85 | Safer topical treatment for inflammation using 5α-tetrahydrocorticosterone in mouse models. ( Abernethie, AJ; Andrew, R; Gastaldello, A; Hadoke, PW; Livingstone, DE; Tsang, N; Walker, BR, 2017) |
| " We recently demonstrated that adult male rats exposed to low doses of corticosterone during lactation (CORT-nursed rats) are protected against experimental colitis induced by the intracolonic infusion of 2,4,6-trinitrobenzenesulfonic acid (TNBS)." | 7.85 | Maternal exposure to low levels of corticosterone during lactation protects adult rat progeny against TNBS-induced colitis: A study on GR-mediated anti-inflammatory effect and prokineticin system. ( Broccardo, M; Canu, N; Casolini, P; Fusco, I; Giuli, C; Lattanzi, R; Marconi, V; Petrella, C; Severini, C; Theodorou, V; Zinni, M; Zuena, AR, 2017) |
| "Neuropeptide Y (NPY) was recently proposed to be associated with stress and airway inflammation; however, this has rarely been studied in animal models of asthma." | 7.83 | An association between neuropeptide Y levels and leukocyte subsets in stress-exacerbated asthmatic mice. ( Ho, RC; Lu, Y, 2016) |
| "Previously published reports have revealed the antidepressant-like effects of icariin in a chronic mild stress model of depression and in a social defeat stress model in mice." | 7.83 | Icariin reverses corticosterone-induced depression-like behavior, decrease in hippocampal brain-derived neurotrophic factor (BDNF) and metabolic network disturbances revealed by NMR-based metabonomics in rats. ( Gong, MJ; Han, B; Liang, SW; Wang, SM; Zou, ZJ, 2016) |
| "The anxiety status is changed along with memory impairments in intracerebroventricular colchicine injected rat model of Alzheimer Disease (cAD) due to neurodegeneration, which has been indicated to be mediated by inflammation." | 7.83 | Cox-2 Plays a Vital Role in the Impaired Anxiety Like Behavior in Colchicine Induced Rat Model of Alzheimer Disease. ( Ghosh, T; Sil, S, 2016) |
| " Since the BDNF hypothesis of depression postulates that a reduction in BDNF is directly involved in the pathophysiology of depression, we evaluated the anti-depressive effects of HMF in mice with subcutaneously administered corticosterone at a dose of 20 mg/kg/day for 25 days." | 7.83 | 3,5,6,7,8,3',4'-Heptamethoxyflavone, a Citrus Flavonoid, Ameliorates Corticosterone-Induced Depression-like Behavior and Restores Brain-Derived Neurotrophic Factor Expression, Neurogenesis, and Neuroplasticity in the Hippocampus. ( Amakura, Y; Furukawa, Y; Nakajima, M; Okuyama, S; Sawamoto, A; Yamamoto, K; Yoshimura, M, 2016) |
| " In this study, we used the chronic corticosterone (CORT)-induced mouse model of anxiety/depression to assess antidepressant-like effects of baicalin and illuminate possible molecular mechanisms by which baicalin affects GR-mediated hippocampal neurogenesis." | 7.83 | Baicalin promotes hippocampal neurogenesis via SGK1- and FKBP5-mediated glucocorticoid receptor phosphorylation in a neuroendocrine mouse model of anxiety/depression. ( Dong, Y; Ma, J; Pan, X; Su, G; Wang, F; Wu, C; Yang, J; Zhang, K, 2016) |
| "The aim of the present study was to investigate the effects of the selective agonists of the corticotropin-releasing factor (CRF) 2 receptor, urocortin 2 (UCN 2) and urocortin 3 (UCN 3), on the anxiety- and depression-like signs induced by acute nicotine withdrawal in mice." | 7.83 | Selective CRF2 receptor agonists ameliorate the anxiety- and depression-like state developed during chronic nicotine treatment and consequent acute withdrawal in mice. ( Bagosi, Z; Balangó, B; Bokor, P; Buzás, A; Csabafi, K; Jászberényi, M; Palotai, M; Pintér, D; Simon, B; Szabó, G, 2016) |
| "In this study, we sought to determine whether resveratrol (RSV), a nonhormonal compound, would suppress the myometrial infiltration, improve pain behavior, lower stress level, improve the expression of some proteins known to be involved in adenomyosis, and reduce uterine contractility in a mice model of adenomyosis." | 7.81 | Resveratrol Reduces Myometrial Infiltration, Uterine Hyperactivity, and Stress Levels and Alleviates Generalized Hyperalgesia in Mice With Induced Adenomyosis. ( Chen, Y; Guo, SW; Liu, X; Zhang, H; Zhu, B, 2015) |
| "The present study focuses on detecting anxiety-like behavior and associated neurochemical alterations in adolescent rats exposed perinatally to bisphenol A (BPA), an estrogen-mimicking endocrine disrupter and investigating the possible involvement of metabotropic glutamate 2/3 receptors (mGlu2/3 receptors) in BPA-induced anxiogenic effects." | 7.81 | Perinatal exposure to low-dose of bisphenol A causes anxiety-like alteration in adrenal axis regulation and behaviors of rat offspring: a potential role for metabotropic glutamate 2/3 receptors. ( Chen, F; Chen, L; Feng, X; Li, Y; Zhou, L; Zhou, R, 2015) |
| "Repeated injection of corticosterone (CORT) induces dysregulation in the hypothalamic-pituitary-adrenal (HPA) axis, resulting in depression." | 7.81 | Angelica gigas ameliorate depression-like symptoms in rats following chronic corticosterone injection. ( Hahm, DH; Lee, B; Lee, H; Shim, I; Sur, B, 2015) |
| " This study was carried out in order to assess the influence of neonatal tactile stimulation (TS) on behavioral and morphological responses related to depression-like and anxiety-like behaviors, assessed following the administration of sertraline (SERT), a selective serotonin re-uptake inhibitor (SSRI)." | 7.81 | Neonatal tactile stimulation decreases depression-like and anxiety-like behaviors and potentiates sertraline action in young rats. ( Antoniazzi, CT; Barcelos, RC; Burger, ME; Duarte, MM; Duarte, T; Freitas, D; Metz, VG; Segat, HJ; Vey, LT, 2015) |
| " Herein, we have described a mouse model of a depression-like and insulin-resistant (DIR) state induced by the co-treatment of high-fat diet (HFD) and corticosterone (CORT)." | 7.80 | Depression-like behaviors in mice subjected to co-treatment of high-fat diet and corticosterone are ameliorated by AICAR and exercise. ( Ji, L; Li, H; Liu, W; Zhai, X, 2014) |
| " Anxiety was evaluated by the elevated plus maze model and by serum corticosterone levels." | 7.80 | Dentin hypersensitivity induces anxiety and increases corticosterone serum levels in rats. ( Bergamini, MR; Bernardi, MM; Ciaramicoli, MT; Kabadayan, F; Kodama, RM; Saraceni, CH; Sufredini, IB, 2014) |
| "Intermittent hypoxia (IH) is an animal model of apnea-induced hypoxia, a common stressor in the premature neonate." | 7.80 | Programming of the hypothalamic-pituitary-adrenal axis by neonatal intermittent hypoxia: effects on adult male ACTH and corticosterone responses are stress specific. ( Bruder, ED; Chintamaneni, K; Raff, H, 2014) |
| "Female rats implanted with 28-day osmotic minipumps delivering the SSRI escitalopram throughout pregnancy had serum escitalopram concentrations in a clinically observed range (17-65 ng/ml)." | 7.79 | Prenatal exposure to escitalopram and/or stress in rats: a prenatal stress model of maternal depression and its treatment. ( Boss-Williams, KA; Bourke, CH; Capello, CF; Owens, MJ; Rogers, SM; Stowe, ZN; Weiss, JM; Yu, ML, 2013) |
| "Ablation of olfactory bulbs caused depression-like symptoms as evidenced by increased immobility time in FST, hyperactivity in open field arena, and anhedonic like response in SPT along with alterations in mitochondrial enzyme complexes, increased serum corticosterone levels and oxidative damage." | 7.79 | Suppression of neuroinflammatory and apoptotic signaling cascade by curcumin alone and in combination with piperine in rat model of olfactory bulbectomy induced depression. ( Garg, S; Kumar, A; Rinwa, P, 2013) |
| "The antidepressant effect of a compound formed by co-ultramicronized palmitoylethanolamide (PEA) and luteolin (PEA+luteolin) was investigated in a mouse model of anxiety/depressive-like behavior." | 7.79 | Effects of palmitoylethanolamide and luteolin in an animal model of anxiety/depression. ( Ahmad, A; Campolo, M; Crupi, R; Cuzzocrea, S; Esposito, E; Paterniti, I, 2013) |
| " Melatonin therapy significantly reduced the thermoregulatory deficit, brain inflammation, ischemia, oxidative damage, hypothalamic-pituitary-adrenal axis impairment, multiple organ dysfunction, and lethality caused by heat stroke." | 7.79 | Melatonin improves outcomes of heatstroke in mice by reducing brain inflammation and oxidative damage and multiple organ dysfunction. ( Hsu, SF; Lin, CH; Lin, MT; Tian, YF, 2013) |
| " This study examined the effects of mGlu2/3 receptor antagonists in chronic corticosterone-treated mice which could be used as an animal model of depression." | 7.79 | Metabotropic glutamate 2/3 receptor antagonists improve behavioral and prefrontal dopaminergic alterations in the chronic corticosterone-induced depression model in mice. ( Ago, Y; Araki, R; Baba, A; Chaki, S; Hashimoto, H; Hiramatsu, N; Kawasaki, T; Kita, Y; Matsuda, T; Nakazato, A; Onoe, H; Takuma, K; Yano, K, 2013) |
| " The present study was designed to monitor effects of injected leptin on immobilization stress-induced anorexia, behavioral deficits, and plasma corticosterone secretion in rats." | 7.79 | Inhibition of immobilization stress-induced anorexia, behavioral deficits, and plasma corticosterone secretion by injected leptin in rats. ( Akbar, N; Haleem, DJ; Haleem, MA; Haque, Z; Yasmin, F, 2013) |
| "Sub-chronic tryptophan depletion (SCTD) is proposed as an animal model for depression." | 7.78 | Sub-chronic dietary tryptophan depletion--an animal model of depression with improved face and good construct validity. ( Bermudez, I; Franklin, M; Gaburro, S; Murck, H; Singewald, N, 2012) |
| "Both chronic mild stress and an injection of corticosterone induce depression-like states in rodents." | 7.78 | Corticosterone reduces brain mitochondrial function and expression of mitofusin, BDNF in depression-like rodents regardless of exercise preconditioning. ( Liu, W; Zhou, C, 2012) |
| "Tolerance to morphine analgesia following repeated administration disturbs the continuation of opioid therapy for severe pain." | 7.78 | Inhibition of morphine tolerance is mediated by painful stimuli via central mechanisms. ( Fukazawa, Y; Iwai, S; Kiguchi, N; Kishioka, S; Kobayashi, Y; Saika, F; Ueno, K; Yamamoto, C, 2012) |
| " In the present study, pain sensitivity was assessed in a mouse model of anxiety/depression on the basis of chronic corticosterone (CORT) administration through the drinking water (CORT model)." | 7.78 | Antinociceptive effects of fluoxetine in a mouse model of anxiety/depression. ( Coudoré, F; David, DJ; Gardier, AM; Guiard, BP; Hache, G; Le Dantec, Y; Orvoën, S, 2012) |
| "Corticosterone plasma levels, locomotor activity, adrenal gland weight and bone loss were increased in periodontitis and stress groups, and there was also less weight gain." | 7.78 | Anti-inflammatory effect of the endocannabinoid anandamide in experimental periodontitis and stress in the rat. ( De Laurentiis, A; Elverdin, JC; Rettori, E; Rettori, V; Zorrilla Zubilete, M, 2012) |
| "The aim of the experiment was to assess the effects of an acutely administered corticosterone on the expression of GABA-A receptor alpha-2 subunits in the brain structures of high (HR) and low (LR) anxiety rats (divided according to their conditioned fear-induced freezing response) subjected to a second conditioned fear session (1 week after fear conditioning)." | 7.78 | Corticosterone attenuates conditioned fear responses and potentiates the expression of GABA-A receptor alpha-2 subunits in the brain structures of rats selected for high anxiety. ( Lehner, M; Maciejak, P; Płaźnik, A; Skórzewska, A; Sobolewska, A; Szyndler, J; Turzyńska, D; Wisłowska-Stanek, A, 2012) |
| "We examined a potential two-hit murine animal model of depression by assessing whether a genetic deficit in reelin increases vulnerability to the depressogenic effects of the stress hormone corticosterone." | 7.77 | Reelin as a putative vulnerability factor for depression: examining the depressogenic effects of repeated corticosterone in heterozygous reeler mice. ( Caruncho, HJ; Kalynchuk, LE; Lussier, AL; Romay-Tallón, R, 2011) |
| " We recently developed a lentivirus (LV) vector that produces an insulin receptor (IR) antisense RNA sequence (IRAS) that when injected into the hypothalamus selectively decreases IR signaling in hypothalamus, resulting in increased body weight, peripheral adiposity and plasma leptin levels." | 7.77 | Obesity/hyperleptinemic phenotype adversely affects hippocampal plasticity: effects of dietary restriction. ( Evans, AN; Grillo, CA; Macht, VA; Mott, DD; Piroli, GG; Reagan, LP; Sakai, RR; Scott, KA; Wilson, SP, 2011) |
| "To observe the effects of icariin, psoralen and oleanolic acid, the three active ingredients of Yinyanghuo (Herba Epimedii Brevicornus), Buguzhi (Fructus Psoraleae) and Nuzhenzi (Fructus Ligustri Lucidi), respectively, on gene expression profile of bone marrow stromal cells (BMSCs) from rats with corticosterone-induced osteoporosis." | 7.77 | [Effects of active ingredients in three kidney-tonifying Chinese herbal drugs on gene expression profile of bone marrow stromal cells from a rat model of corticosterone-induced osteoporosis]. ( Bian, Q; Huang, JH; Ning, Y; Shen, ZY; Wang, YJ; Yang, Z; Zhao, YJ, 2011) |
| " Basally, HRs display lower anxiety-like behavior compared to LRs along with higher neuropeptide Y (NPY) mRNA in the amygdala and the hippocampus." | 7.77 | Effects of a selective Y2R antagonist, JNJ-31020028, on nicotine abstinence-related social anxiety-like behavior, neuropeptide Y and corticotropin releasing factor mRNA levels in the novelty-seeking phenotype. ( Aydin, C; Isgor, C; Oztan, O, 2011) |
| "Sandhoff disease (SD) is a lysosomal disease caused by a mutation of the HEXB gene associated with excessive accumulation of GM2 ganglioside (GM2) in lysosomes and neurological manifestations." | 7.77 | Thymic involution and corticosterone level in Sandhoff disease model mice: new aspects the pathogenesis of GM2 gangliosidosis. ( Itoh, K; Matsuoka, K; Taki, T; Tsuji, D, 2011) |
| "To investigate further whether low leptin levels alone were responsible for delayed puberty in colitis, we induced colitis in 23-day-old female mice using 3% dextran sodium sulfate (DSS), resulting in 10 days of worsening colitis." | 7.76 | Colitis causes delay in puberty in female mice out of proportion to changes in leptin and corticosterone. ( Cohn, S; DeBoer, MD; Li, Y, 2010) |
| " We found that high doses of CORT (100 microg/ml) result in rapid and dramatic increases in weight gain, increased adiposity, elevated plasma leptin, insulin and triglyceride levels, hyperphagia, and decreased home-cage locomotion." | 7.76 | Endocrine and physiological changes in response to chronic corticosterone: a potential model of the metabolic syndrome in mouse. ( Bhagat, SM; Bowles, NP; Karatsoreos, IN; McEwen, BS; Pfaff, DW; Weil, ZM, 2010) |
| " We characterized the pharmacokinetic/pharmacodynamic relationships of a prototypical ASI, (+)-(5R)-4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl]benzonitrile hydrochloride (CGS020286A, FAD286, FAD) and compared these profiles to those of the 11beta-hydroxylase inhibitor metyrapone (MET) in two rodent models of secondary hyperaldosteronism and corticosteronism." | 7.76 | Pharmacodynamic and pharmacokinetic characterization of the aldosterone synthase inhibitor FAD286 in two rodent models of hyperaldosteronism: comparison with the 11beta-hydroxylase inhibitor metyrapone. ( Beil, M; Fu, F; Hu, CW; Jeng, AY; Liang, G; Rigel, DF, 2010) |
| "The results indicate that nicotine enhances susceptibility to periodontitis via nAChRs, which may act via suppressing protective immune responses through the cholinergic anti-inflammatory pathway." | 7.75 | Nicotinic acetylcholine receptor activation mediates nicotine-induced enhancement of experimental periodontitis. ( Breivik, T; Gjermo, P; Gundersen, Y; Opstad, PK; von Hörsten, S, 2009) |
| "Thus, we examined the response to peripheral exenatide using telemetry in conscious, unrestrained rats under normotensive conditions and in a model of hypertension/metabolic syndrome induced by corticosterone." | 7.75 | Exenatide improves hypertension in a rat model of the metabolic syndrome. ( Guss, S; Landry, J; Laugero, KD; Parkes, DG; Stonehouse, AH; Vu, C, 2009) |
| " Here we describe a mouse model of an anxiety/depressive-like state induced by chronic corticosterone treatment." | 7.75 | Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression. ( Antonijevic, IA; Artymyshyn, RP; Craig, DA; David, DJ; Drew, M; Gardier, AM; Gerald, C; Guiard, BP; Guilloux, JP; Hen, R; Leonardo, ED; Marsteller, D; Mendez, I; Rainer, Q; Samuels, BA; Wang, JW, 2009) |
| "The data demonstrate that EA activates the adrenals to increase plasma corticosterone levels and suppress edema and suggest that EA effects differ in healthy subjects and in those with pathologies." | 7.74 | Corticosterone mediates electroacupuncture-produced anti-edema in a rat model of inflammation. ( Berman, BM; Lao, L; Li, A; Ren, K; Tan, M; Wang, Y; Zhang, H; Zhang, RX, 2007) |
| "Cholecystokinin (CCK) involvement in depression-like disorders is poorly documented." | 7.74 | Repeated social defeat-induced depression-like behavioral and biological alterations in rats: involvement of cholecystokinin. ( Becker, C; Benoliel, JJ; Blugeot, A; Hamon, M; Rivat, C; Zeau, B, 2008) |
| "A rat model of depression has been recently developed by exogenous corticosterone administration." | 7.74 | A mouse model of depression induced by repeated corticosterone injections. ( Du, L; Ma, R; Shen, J; Su, H; Xing, D; Zhao, Y, 2008) |
| " The purpose of the present study was to characterize the effect of repeated corticosterone (CORT) injections and repeated restraint stress on anxiety and depression-like behavior in male rats." | 7.73 | Effect of repeated corticosterone injections and restraint stress on anxiety and depression-like behavior in male rats. ( Davis, AC; Gregus, A; Kalynchuk, LE; Wintink, AJ, 2005) |
| "C57BL/6 mice were either fed ad libitum or fasted for 48 h and given an intraperitoneal injection of saline or recombinant leptin (1 microg/g of body weight) twice daily for 48 h before bacterial challenge." | 7.73 | Leptin corrects host defense defects after acute starvation in murine pneumococcal pneumonia. ( Huffnagle, GB; Mancuso, P; Olszewski, MA; Peters-Golden, M; Phipps, J, 2006) |
| " We studied mice bearing a truncated Mecp2 allele (Mecp2(308/Y) mice) and found evidence of increased anxiety-like behavior and an abnormal stress response as evidenced by elevated serum corticosterone levels." | 7.73 | Enhanced anxiety and stress-induced corticosterone release are associated with increased Crh expression in a mouse model of Rett syndrome. ( Bundle, SF; Carson, JP; McGill, BE; Thaller, C; Yaylaoglu, MB; Zoghbi, HY, 2006) |
| "Topiramate is currently used in the treatment of epilepsy, but this anticonvulsant drug has also been reported to exert mood-stabilizing effects and induce weight loss in patients." | 7.72 | Topiramate normalizes hippocampal NPY-LI in flinders sensitive line 'depressed' rats and upregulates NPY, galanin, and CRH-LI in the hypothalamus: implications for mood-stabilizing and weight loss-inducing effects. ( Bolwig, G; Husum, H; Mathé, A; Termeer, E; Van Kammen, D, 2003) |
| "Previous studies on human breast cancer patients showed a decline in circulating melatonin levels corresponding to primary tumor growth and an increase when relapse occurred." | 7.70 | Serial transplants of DMBA-induced mammary tumors in Fischer rats as a model system for human breast cancer. VI. The role of different forms of tumor-associated stress for the regulation of pineal melatonin secretion. ( Bartsch, C; Bartsch, H; Besenthal, I; Buchberger, A; Effenberger-Klein, A; Kruse-Jarres, JD; Mecke, D; Rokos, H; Stieglitz, A, 1999) |
| "30% of patients with essential hypertension have a decreased adrenal response to angiotensin II (A II) on a low but not a high sodium intake." | 7.66 | Decreased adrenal responsiveness to angiotensin II: a defect present in spontaneously hypertensive rats. A possible model of human essential hypertension. ( Braley, LM; Menachery, A; Williams, GH, 1982) |
| "Olanzapine treatment reduced development of ABA in rats by reducing running wheel activity, starvation-induced hypothermia and activation of the hypothalamus-pituitary-adrenal axis." | 6.71 | Olanzapine reduces physical activity in rats exposed to activity-based anorexia: possible implications for treatment of anorexia nervosa? ( Adan, RA; Hillebrand, JJ; Kas, MJ; van Elburg, AA; van Engeland, H, 2005) |
| "Quercetin is a flavonoid compound, which has anti-inflammatory and antioxidant roles." | 5.91 | Quercetin mitigates depression-like behavior via the suppression of neuroinflammation and oxidative damage in corticosterone-induced mice. ( Ge, C; Lei, L; Wang, S; Wu, X, 2023) |
| "Twenty days after ovariectomy, PTSD was induced by single prolonged stress (SPS) model." | 5.72 | Effect of treadmill exercise on serum corticosterone, serum and hippocampal BDNF, hippocampal apoptosis and anxiety behavior in an ovariectomized rat model of post-traumatic stress disorder (PTSD). ( Akhoundzadeh, K; Roshani, F; Shafia, S; Yakhkeshi, R, 2022) |
| "Major depression is a leading contributor to the global burden of disease." | 5.72 | Lower antidepressant response to fluoxetine is associated with anxiety-like behavior, hippocampal oxidative imbalance, and increase on peripheral IL-17 and IFN-γ levels. ( Becker, G; Bochi, GV; Camargo, LFM; da Silva Carlotto, M; Dos Santos, BM; Fialho, MFP; Oliveira, SM; Pereira, GC; Pillat, MM; Piton, E; Ramanzini, LG; Trevisan, G; Zanchet, EM, 2022) |
| "Depression is a common, chronic, and often recurrent serious mood disorder." | 5.72 | Neuroprotective and Antioxidant Effects of Riparin I in a Model of Depression Induced by Corticosterone in Female Mice. ( Adelvane de Paula Rodrigues, F; Barbosa-Filho, JM; Cavalcanti Capibaribe, VC; Chavez Gutierrez, SJ; de Castro Chaves, R; Ferreira de Oliveira, N; Florenço de Sousa, FC; Lopes Sales, IS; Maia Oliveira, IC; Maria de França Fonteles, M; Rodrigues de Carvalho, AM; Rodrigues, GC; Teodorio Vidal, LM; Vasconcelos Mallmann, AS, 2022) |
| "Another pandemic disease is type II diabetes mellitus (T2D) that is estimated to affect half a billion people in the world." | 5.62 | 16α-Bromoepiandrosterone as a new candidate for experimental diabetes-tuberculosis co-morbidity treatment. ( Baay-Guzman, G; Barrios-Payan, JA; Bini, E; Carranza, A; Chamberlin, W; Ge, Y; Hernández-Pando, R; López-Torres, MO; Marquina-Castillo, B; Mata-Espinosa, D; Ramos-Espinosa, O; Torre-Villalvazo, I; Torres, N; Tovar, A; Yepez, SH, 2021) |
| "Corticosterone plasma level was increased in the CUMS compared to the non-stressed group (p < 0." | 5.56 | Valproic acid administration exerts protective effects against stress-related anhedonia in rats. ( Barati, M; Eslami, M; Goudarzi, M; Mehrabi, S; Nahavandi, A; Shahbazi, A, 2020) |
| "Depression is recognized as a highly chronic and recurrent disorder." | 5.56 | Cyclical administration of corticosterone results in aggravation of depression-like behaviors and accompanying downregulations in reelin in an animal model of chronic stress relevant to human recurrent depression. ( Allen, J; Caruncho, HJ; Kalynchuk, LE; Kulhawy, EY; Lebedeva, KA, 2020) |
| "Depression is closely linked to hypothalamus-pituitary-adrenal axis hyperactivity." | 5.56 | Antidepressant-like mechanism of honokiol in a rodent model of corticosterone-induced depression. ( Chang, HS; Duan, XH; Hu, KL; Li, LN; Li, Y; Liu, M; Yu, X; Zhang, B, 2020) |
| "Minimal hepatic encephalopathy (MHE) is characterized as cognitive deficits including memory and learning dysfunctions after liver injuries or hepatic diseases." | 5.51 | Corticosterone-mediated microglia activation affects dendritic spine plasticity and motor learning functions in minimal hepatic encephalopathy. ( Cheng, T; Han, R; So, KF; Sun, X; Xiao, J; Zhang, L; Zheng, Y, 2019) |
| " RESULTS The results showed that the extract at the dosage of 50 and 100 mg/kg significantly (p<0." | 5.51 | Antidepressive Effects of Taraxacum Officinale in a Mouse Model of Depression Are Due to Inhibition of Corticosterone Levels and Modulation of Mitogen-Activated Protein Kinase Phosphatase-1 (Mkp-1) and Brain-Derived Neurotrophic Factor (Bdnf) Expression. ( Duan, H; Gao, C; Guo, B; Kong, S; Li, D; Liang, X, 2019) |
| "Baicalein was injected intraperitoneally to TLE rats for two weeks after the onset of spontaneous recurrent seizures (SRS)." | 5.51 | Baicalein improves cognitive deficits and hippocampus impairments in temporal lobe epilepsy rats. ( Ding, JQ; Li, W; Qian, X; Wang, ZR; Zhang, M; Zhang, TY; Zheng, JJ; Zhong, JG, 2019) |
| "Quercetin treatment was found to significantly reduce anxiety-like behaviors in mTBI-induced mice." | 5.51 | Quercetin mitigates anxiety-like behavior and normalizes hypothalamus-pituitary-adrenal axis function in a mouse model of mild traumatic brain injury. ( Ghorbanihaghjo, A; Kosari-Nasab, M; Mesgari-Abbasi, M; Salari, AA; Shokouhi, G, 2019) |
| "Corticosterone treatment altered all parameters in behavioral tests, leading to a depressive- and anxious-like behavior." | 5.51 | Reversal effect of Riparin IV in depression and anxiety caused by corticosterone chronic administration in mice. ( Barbosa Filho, JM; Capibaribe, VCC; Chaves, RC; da Silva, DMA; de Carvalho, AMR; de Sousa, FCF; Gutierrez, SJC; Lopes, IS; Macêdo, DS; Mallmann, ASV; Oliveira, ICM; Oliveira, NF; Valentim, JT; Vasconcelos, SMM, 2019) |
| "Oxytocin (OXT) has been considered as a neuroregulator mediating social behaviors and stress-related disorders." | 5.48 | Injection of oxytocin into paraventricular nucleus reverses depressive-like behaviors in the postpartum depression rat model. ( Li, H; Li, X; Liu, B; Shi, C; Wang, H; Wang, T; Wang, Y; Wu, Y; Xu, ZD; Yang, Y; Zhang, P, 2018) |
| " At the end of dosing schedule, neurobehavioral tests were conducted; followed by mechanistic evaluation through biochemical analysis, RTPCR and western blot in serum and hippocampus." | 5.48 | Antidepressant activity of vorinostat is associated with amelioration of oxidative stress and inflammation in a corticosterone-induced chronic stress model in mice. ( Js, IC; Kv, A; Lahkar, M; Madhana, RM; Naidu, VGM; Sinha, S, 2018) |
| "Baicalin treatment inhibited APPL2/GR signaling pathway and improved neurogenesis at SVZ, OB, and hippocampus in APPL2 Tg mice and chronic corticosterone-induced depression mouse model." | 5.48 | Baicalin Modulates APPL2/Glucocorticoid Receptor Signaling Cascade, Promotes Neurogenesis, and Attenuates Emotional and Olfactory Dysfunctions in Chronic Corticosterone-Induced Depression. ( Deng, R; Du, Q; Gao, C; Li, W; Shen, J; Wang, Q; Xu, A, 2018) |
| "Corticosterone pre-treatment generated oxidative stress, altering antioxidant enzymes in the nervous tissue." | 5.48 | Antioxidant and antidepressant-like effects of Eugenia catharinensis D. Legrand in an animal model of depression induced by corticosterone. ( Alberton, MD; Barauna, SC; Brueckheimer, MB; de Albuquerque, CAC; de Gasper, AL; de Melo, DFM; Delwing-Dal Magro, D; Delwing-De Lima, D; Döhler, AW; Harger, MC; Maia, TP; Micke, GA; Sala, GABN; Siebert, DA, 2018) |
| "Oxytocin (OXT) is a neuropeptide that regulates sexual reproduction and social interaction and has recently earned specific attention due to its role in adjusting neurobiological and behavioral correlates of PTSD; however, the mechanism by which this is achieved remains unclear." | 5.48 | Effects of Oxytocin on Fear Memory and Neuroinflammation in a Rodent Model of Posttraumatic Stress Disorder. ( Chen, CC; Lin, CC; Liu, YP; Tzeng, NS; Wang, SC, 2018) |
| "Insulin resistance has been identified as the key mechanism linking depression and diabetes." | 5.46 | Curcumin reverses the depressive-like behavior and insulin resistance induced by chronic mild stress. ( Li, YC; Li, YJ; Qiao, JY; Shen, JD; Wei, Y, 2017) |
| " Chronic administration of AS101 significantly reduced anxiety-like behavior of Sub mice in the elevated plus maze, according to both time spent and entries to open arms, relative to vehicle-treated controls." | 5.46 | The immunomodulatory tellurium compound ammonium trichloro (dioxoethylene-O,O') tellurate reduces anxiety-like behavior and corticosterone levels of submissive mice. ( Gross, M; Kenigsbuch-Sredni, D; Pinhasov, A; Sredni, B; Stanciu, E, 2017) |
| "Recently, depression has been envisioned as more than an alteration in neurotransmitters centered around receptor signaling pathways." | 5.46 | Fluoxetine coupled with zinc in a chronic mild stress model of depression: Providing a reservoir for optimum zinc signaling and neuronal remodeling. ( Omar, NN; Tash, RF, 2017) |
| "Comorbid depression was induced by five inescapable foot-shocks (2mA, 2ms duration) at 10s intervals on days 1, 5, 7, and 10." | 5.46 | Metformin and ascorbic acid combination therapy ameliorates type 2 diabetes mellitus and comorbid depression in rats. ( Kumar, M; Nayak, PK; Shivavedi, N; Tej, GNVC, 2017) |
| "Depression has become a common public health problem that is showing increasing prevalence." | 5.46 | Evaluation of the antidepressant-like effect of musk in an animal model of depression: how it works. ( Ayuob, NN, 2017) |
| "Musk has an antidepressant-like effect in an animal model of depression, so it is advisable to assess its efficacy in people continually exposed to stressors." | 5.43 | The antidepressant effect of musk in an animal model of depression: a histopathological study. ( Ahmed, SM; Ali, SS; Ayuob, NN; El Wahab, MGA; Suliaman, M, 2016) |
| " Chronic administration of BB effectively reversed these alterations." | 5.43 | Bilobalide alleviates depression-like behavior and cognitive deficit induced by chronic unpredictable mild stress in mice. ( Shui, L; Song, Z; Tai, F; Wang, S; Wu, R, 2016) |
| "Chronic pain and depression are two complex states that often coexist in the clinical setting and traditional antidepressants and analgesics have shown limited clinical efficacy." | 5.42 | m-Trifluoromethyl-diphenyl diselenide, a multi-target selenium compound, prevented mechanical allodynia and depressive-like behavior in a mouse comorbid pain and depression model. ( Brüning, CA; Duarte, MM; Gai, BM; Martini, F; Nogueira, CW; Sampaio, TB; Soares, SM, 2015) |
| "Corticosterone level was measured using ELISA Kit while BDNF levels were assessed using ELISA Chemikine TM BDNF kit." | 5.42 | Biochemical and cognitive impairments observed in animal models of schizophrenia induced by prenatal stress paradigm or methylazoxymethanol acetate administration. ( Giermaziak, W; Kus, K; Murawiecka, P; Nowakowska, E; Ratajczak, P; Słodzińska, I, 2015) |
| "Anxiety and depression are common in diabetics." | 5.40 | Anxiety- and depression-like behavior are correlated with leptin and leptin receptor expression in prefrontal cortex of streptozotocin-induced diabetic rats. ( Agilkaya, S; Aksu, I; Ates, M; Baykara, B; Buyuk, E; Cetinkaya, C; Cingoz, S; Dayi, A; Kiray, M; Sisman, AR; Uysal, N, 2014) |
| " Additionally, the effects of chronic administration of the tricyclic antidepressant imipramine and the anti-TNF-α pentoxyphylline were investigated." | 5.40 | Lipopolysaccharide repeated challenge followed by chronic mild stress protocol introduces a combined model of depression in rats: reversibility by imipramine and pentoxifylline. ( Abd-Alkhalek, HA; Abdel-tawab, AM; Aboul-Fotouh, S; El Tabbal, M; Elgarf, AS; Farrag, KA; Hammouda, GA; Hassan, AN; Kassim, SK, 2014) |
| "Corticosterone treatment induced longer immobility times in the FST, reflecting depressive-like behaviour." | 5.40 | Long-term corticosterone exposure decreases insulin sensitivity and induces depressive-like behaviour in the C57BL/6NCrl mouse. ( Blokland, A; Cañete, R; Pawluski, JL; Sierksma, AS; Steinbusch, HW; Vaessen, KR; van Donkelaar, EL, 2014) |
| "Honokiol (HNK) is a biphenolic neolignan possessing multiple biological activities including antioxidant, anti-inflammatory, anxiolytic, antidepressant and neuroprotective." | 5.40 | Honokiol abrogates lipopolysaccharide-induced depressive like behavior by impeding neuroinflammation and oxido-nitrosative stress in mice. ( Baruah, CC; Dwivedi, S; Hazarika, NK; Jangra, A; Kumar, P; Lahkar, M; Sulakhiya, K, 2014) |
| "Propranolol is a β-adrenergic antagonist commonly used in the treatment of hypertension or acute anxiety." | 5.39 | Propranolol reduces cognitive deficits, amyloid β levels, tau phosphorylation and insulin resistance in response to chronic corticosterone administration. ( Aguirre, N; Dobarro, M; Orejana, L; Ramírez, MJ, 2013) |
| "Obesity is a disease that has become a serious public health issue worldwide, and chronic stressors, which are a problem for modern society, cause neuroendocrine changes with alterations in food intake." | 5.38 | Cafeteria diet-induced obesity plus chronic stress alter serum leptin levels. ( Caumo, W; Cioato, SG; Macedo, IC; Medeiros, LF; Oliveira, C; Oliveira, CM; Rozisky, JR; Santos, VS; Scarabelot, VL; Silva, FR; Souza, A; Torres, IL, 2012) |
| "Anticipatory nausea is produced by pairing a novel distinctive context with the nausea-inducing effects of a toxin, such as LiCl." | 5.37 | Acute corticosterone increases conditioned spontaneous orofacial behaviors but fails to influence dose related LiCl-induced conditioned "gaping" responses in a rodent model of anticipatory nausea. ( Biagi, E; Chan, MY; Cloutier, CJ; Cross-Mellor, SK; Kavaliers, M; Ossenkopp, KP, 2011) |
| "Obesity is an increasing socio-economic health problem." | 5.35 | Diet-induced obesity alters behavior as well as serum levels of corticosterone in F344 rats. ( Behrendt, P; Bode, FJ; Brabant, G; Buchenauer, T; Horn, R; Nave, H; Stephan, M, 2009) |
| "ACTH-induced-hypertension is commonly employed as a model of stress-related hypertension, and despite extensive investigation, the mechanisms underlying elevated blood pressure (BP) are not well understood." | 5.35 | ACTH-induced hypertension is dependent on the ouabain-binding site of the alpha2-Na+-K+-ATPase subunit. ( Dostanic-Larson, I; Lasko, V; Lingrel, JB; Loreaux, EL; Lorenz, JN; Paul, RJ; Schnetzer, JR, 2008) |
| "Electroconvulsive seizure (ECS)-treatment, an animal model for the antidepressant treatment electroconvulsive therapy, can enhance proliferation of glial cells." | 5.33 | Corticosterone-induced inhibition of gliogenesis in rat hippocampus is counteracted by electroconvulsive seizures. ( Ekstrand, J; Hellsten, J; Lindgren, H; Tingström, A; Wennström, M, 2006) |
| "Gastric ulcer is a source of visceral pain." | 5.33 | Somatic pain sensitivity during formation and healing of acetic acid-induced gastric ulcers in conscious rats. ( Bogdanov, A; Filaretova, L; Yarushkina, N, 2006) |
| "In rats with acute hepatic failure, the hepatic P-glycoprotein concentration increased 1." | 5.31 | Expression and function of P-glycoprotein in rats with carbon tetrachloride-induced acute hepatic failure. ( Huang, ZH; Murakami, T; Nagai, J; Okochi, A; Takano, M; Yumoyo, R, 2001) |
| " Because teratogenic effects follow a toxicologic dose-response curve with a no-effect dose, frequently counselors can refute a causal relationship because the dose was far below the no-observable-effect dose." | 5.29 | Is there a no-effect dose for corticosteroid-induced cleft palate? The contribution of endogenous corticosterone to the incidence of cleft palate in mice. ( Beckman, DA; Brent, RL; Buck, SJ; Fawcett, LB, 1996) |
| "Diazepam treatment alleviates in the first session aversion towards open space and hight in the elevated plus-maze only in the genetically hypertensive rats of both sexes and in the normotensive males." | 5.28 | Animal model of anxiety: effect of acute diazepam treatment in the older adult genetically hypertensive rats of Koletsky type and in the older adult rats of Wistar strain. ( Golda, V; Petr, R, 1989) |
| " The observed effects, which included increased adrenal weight, decreased thymus weight, increased corticosterone levels, and increased anxiety-like behavior, were very similar to the described effects of this paradigm in male mice." | 5.14 | A novel chronic social stress paradigm in female mice. ( Harbich, D; Holsboer, F; Liebl, C; Mayer, B; Müller, MB; Scharf, SH; Schmidt, MV, 2010) |
| " Elevated serum corticosterone in both zinc deficient and pair-fed rats does not support the hypothesis that zinc deficiency per se leads to corticosterone-induced apoptosis and lymphopenia." | 4.88 | Dietary zinc deficiency in rodents: effects on T-cell development, maturation and phenotypes. ( Blewett, HJ; Taylor, CG, 2012) |
| " These data show altogether that while increased turnover of noradrenaline in the hypothalamus, along with anxiety-like behaviors and increase in serum corticosterone are present very often, the magnitude of changes in immunity may vary considerably." | 4.86 | Neuroimmune interactions in stress. ( Costa-Pinto, FA; Palermo-Neto, J, 2010) |
| " In this study we have evaluated the MMP-9 activity and protein expression in brain areas relevant to depression using the chronic corticosterone mouse model of depression." | 4.31 | Brain matrix metalloproteinase-9 activity is altered in the corticosterone mouse model of depression. ( Breviario, S; Castro, E; Díaz, Á; Florensa-Zanuy, E; Garro-Martínez, E; Pazos, Á; Pilar-Cuéllar, F; Senserrich, J, 2023) |
| " Thereafter, behavior parameters (sucrose preference test, forced-swimming test, open-field test, body weight), pro-inflammatory cytokines, neurotransmitters, adrenocorticotropic hormone (ACTH), corticosterone (CORT), and liver biomarkers were studied." | 4.31 | 18β-Glycyrrhetinic Acid Ameliorates Neuroinflammation Linked Depressive Behavior Instigated by Chronic Unpredictable Mild Stress via Triggering BDNF/TrkB Signaling Pathway in Rats. ( Gupta, GL; Sharma, L; Sharma, M, 2023) |
| "Here, we employed mouse models of depression induced by chronic unpredictable stress exposure or corticosterone (CORT) stimulation." | 4.31 | MAD2B Blunts Chronic Unpredictable Stress and Corticosterone Stimulation-Induced Depression-Like Behaviors in Mice. ( Meng, X; Miao, C; Su, Y; Wang, XL; Zhang, C, 2023) |
| "Using 2 distinct animal models, this study shows that in mice, early life stress leads to reduced colonic corticosterone and that induction of colitis after stress removal results in reduced transcription of glucocorticoid synthesis genes, increased Tnf, and enhanced chronicity of intestinal inflammation." | 4.31 | Early Life Stress in Mice Leads to Impaired Colonic Corticosterone Production and Prolonged Inflammation Following Induction of Colitis. ( Alexander, KL; Foote, JB; Hsu, JS; Jennings, MS; Kellum, CE; Klocke, BJ; Lee, G; Lorenz, RG; Maynard, CL; Molina, PA; Muir, RQ; Pollock, JS, 2023) |
| " Metyrapone, an inhibitor of corticosterone synthesis, completely abolished seizures in GAERS, and seizures remained suppressed for >2 h." | 4.31 | Metyrapone abolishes spike-wave discharge seizures in genetic absence epilepsy rats from Strasbourg by reducing stress hormones. ( Dezsi, G; Harris, G; Jones, NC; O'Brien, TJ; Ozturk, E; Paul, C, 2023) |
| "The corticosterone (CORT)-induced depression mouse model was used to evaluate the therapeutic efficacy of JTW." | 4.12 | Anti-depressive effects of Jiao-Tai-Wan on CORT-induced depression in mice by inhibiting inflammation and microglia activation. ( Bai, G; Duan, L; Huang, S; Li, M; Lo, PC; Qiao, Y; Song, L; Wang, Q; Wei, S; Yang, C; Yang, Y; Zhang, B, 2022) |
| "Mirtazapine (MIRT) is a multi-target antidepressant used in treatment of severe depression with promising efficacy, but also with important side effects, mainly sedation and weight gain." | 4.12 | Lipoic acid prevents mirtazapine-induced weight gain in mice without impairs its antidepressant-like action in a neuroendocrine model of depression. ( Chaves Filho, AJM; Cunha, NL; De Oliveira, GMF; Gadelha Filho, CVJ; Jucá, PM; Macedo, DS; Oliveira, TQ; Soares, MVR; Vasconcelos, SMM; Viana, GA; Vieira, CFX, 2022) |
| " To evaluate the antidepressant-like effects of FMN, a mice model of depression was established by chronic corticosterone (CORT) injection." | 4.12 | The antidepressant-like effect of formononetin on chronic corticosterone-treated mice. ( Bai, M; Li, M; Li, Y; Lu, S; Xu, E; Zhang, C; Zhu, L, 2022) |
| "The aim of this study was to investigate the antidepressant effect of Jujuboside A (JuA) on corticosterone (CORT)-induced depression in mice and explore the underlying mechanisms." | 4.12 | Antidepressant effect of Jujuboside A on corticosterone-induced depression in mice. ( Gong, J; Li, H; Li, J; Xie, X; Zhang, T, 2022) |
| " PPD rat models were prepared by withdrawing hormone‑simulated pregnancy (HSP), and subjects were treated with paeoniflorin and fluoxetine or plasmids." | 4.12 | Paeoniflorin exhibits antidepressant activity in rats with postpartum depression via the TSPO and BDNF‑mTOR pathways. ( Chen, J; Hu, L; Peng, H; Yang, K; Zeng, X; Zhu, W, 2022) |
| "CUMS exposure induced depression-like behaviors, lighter body weight, and increased serum corticosterone levels in mice." | 4.12 | Psychological stress induces moderate pathology in the ganglion cell layer in mice. ( Fan, Z; Ge, J; Guo, C; Han, Y; Lee, JH; Sun, N; Yu, X; Zhang, D; Zhang, J; Zhao, Z, 2022) |
| " We investigated the contribution of 11β-HSD1 to the anti-inflammatory properties of the active GC corticosterone, administered at therapeutic doses in murine models of polyarthritis." | 4.02 | Local steroid activation is a critical mediator of the anti-inflammatory actions of therapeutic glucocorticoids. ( Campos, J; Chimen, M; Cooper, M; Croft, A; Fenton, C; Hardy, RS; Jones, R; Lavery, GG; Martin, C; Naylor, AJ; Raza, K; Taylor, AE, 2021) |
| "Since 2012, studies in mice, rats, and humans have suggested that abnormalities in purinergic signaling may be a final common pathway for many genetic and environmental causes of autism spectrum disorder (ASD)." | 4.02 | Metabolic and behavioral features of acute hyperpurinergia and the maternal immune activation mouse model of autism spectrum disorder. ( Blake, DR; Hirsch, CM; Le, TP; Li, K; Meinardi, S; Monk, JM; Nakayama, T; Naviaux, JC; Naviaux, RK; Wang, L; Zolkipli-Cunningham, Z, 2021) |
| "Carbonyl reductase 1 (Cbr1), a recently discovered contributor to tissue glucocorticoid metabolism converting corticosterone to 20β-dihydrocorticosterone (20β-DHB), is upregulated in adipose tissue of obese humans and mice and may contribute to cardiometabolic complications of obesity." | 4.02 | Carbonyl reductase 1 amplifies glucocorticoid action in adipose tissue and impairs glucose tolerance in lean mice. ( Allan, E; Beck, KR; Bell, RMB; Coutts, A; Denham, SG; Fawkes, A; Homer, NZM; Houtman, R; Koerner, MV; Lee, P; Meijer, OC; Miguelez-Crespo, A; Morgan, RA; Murphy, L; Nixon, M; Odermatt, A; Sharp, MGF; Villalobos, E; Walker, BR, 2021) |
| "Intranasal treatment with oxytocin showed beneficial effects in post-traumatic stress disorder and autism spectrum disorders; however, it was not investigated as much in depression." | 4.02 | Synergy of oxytocin and citalopram in modulating Itgb3/Chl1 interplay: Relevance to sensitivity to SSRI therapy. ( Batinić, B; Gurwitz, D; Israel-Elgali, I; Jukić, M; Oved, K; Pešić, V; Puškaš, N; Shomron, N; Stanić, D, 2021) |
| " In this study, using rat TBI model (lateral fluid percussion cortical injury), we assessed potential association of immediate posttraumatic seizures and changes in corticosterone (CS) levels with neuroinflammation and neuronal cell loss in the hippocampus." | 4.02 | Neuroinflammation and Neuronal Loss in the Hippocampus Are Associated with Immediate Posttraumatic Seizures and Corticosterone Elevation in Rats. ( Frankevich, SO; Gulyaeva, NV; Komoltsev, IG; Moiseeva, JV; Novikova, MR; Onufriev, MV; Shirobokova, NI; Volkova, AA, 2021) |
| " In this study, an ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method was developed to detect the concentration of corticosterone (CORT) and its metabolites, progesterone (PROG) and testosterone in rat plasma and prefrontal cortex (PFC), and was applied to investigate the changes in hormones in rats with depression induced by chronic unpredictable mild stress (CUMS)." | 4.02 | Quantitation of six steroid hormones by ultra-performance liquid chromatography-tandem mass spectrometry in plasma and prefrontal cortex samples from rats with chronic unpredictable mild stress-induced depression. ( Han, X; Li, X; Lu, Y; Qin, Y; Rang, Y; Zhai, X; Zhu, Y, 2021) |
| " Our previous studies found that melatonin exerts an improvement effect in sleep deprivation (SD)- induced corticosterone overproduction and colitis." | 4.02 | Melatonin Ameliorates Corticosterone-Mediated Oxidative Stress-Induced Colitis in Sleep-Deprived Mice Involving Gut Microbiota. ( Cao, J; Chen, Y; Dong, Y; Gao, T; Wang, Z, 2021) |
| " Here, we assessed severity in a cognitive depression model by analysing indicators of stress and well-being, including physiological (body weight and corticosterone metabolite concentrations) and behavioural (nesting and burrowing behaviour) parameters." | 3.96 | Systematic analysis of severity in a widely used cognitive depression model for mice. ( Bleich, A; Brandwein, C; Chourbaji, S; Gass, P; Häger, C; Hellweg, R; Inta, D; Mallien, AS; Palme, R; Pfeiffer, N; Struve, B; Talbot, SR; Vogt, MA; Vollmayr, B, 2020) |
| "Pharmaceutically available enhancer selegiline/(-)-deprenyl (DEP) in the clinically used dose shows antidepressant effect, but nothing is known about this effect in enhancer dose, and its effect on co-morbid anxiety." | 3.96 | Synthetic enhancer compounds, besides acting on biogenic amine system, influence the glutamate transmission and stress response. ( Baghy, K; Knoll, J; Mervai, Z; Miklya, I; Timar, J; Zelena, D, 2020) |
| " Here, we investigated the effects of stress exposure via two types of restraint apparatuses on body weight, locomotor activity, anxiety- and depression-related behaviors, and plasma corticosterone levels in mice." | 3.96 | Differential effects of stress exposure via two types of restraint apparatuses on behavior and plasma corticosterone level in inbred male BALB/cAJcl mice. ( Miyakawa, T; Shoji, H, 2020) |
| " Body weight, levels of plasma corticosterone, hippocampal pro-and anti-inflammatory cytokines, anxiety-like (novelty suppressed feeding and elevated plus maze) and motivated behaviors (sucrose negative contrast test and forced swim test) were evaluated three days after the end of the chronic protocol." | 3.96 | Chronic unpredictable restraint stress increases hippocampal pro-inflammatory cytokines and decreases motivated behavior in rats. ( Covolan, L; da Silva, SG; Hamani, C; Mograbi, KM; Suchecki, D, 2020) |
| " Here we aimed to compare the effects of (R)-norketamine ((R)-NK), (S)-NK, (2R,6R)-HNK, and (2S,6S)-HNK in a mouse model of depression induced by chronic corticosterone (CORT) injection." | 3.96 | (S)-norketamine and (2S,6S)-hydroxynorketamine exert potent antidepressant-like effects in a chronic corticosterone-induced mouse model of depression. ( Ago, Y; Chen, L; Hashimoto, H; Hashimoto, K; Higuchi, M; Kasai, A; Naito, M; Nakagawa, S; Nakazawa, T; Seiriki, K; Tanabe, W; Tsukada, S; Yamaguchi, T; Yokoyama, R, 2020) |
| " Here, we decided to investigate how the duration of the CUMS procedure affects behavioural changes, body weight as well as the level of plasma corticosterone in stressed and nonstressed C57BL/6J mice subjected to CUMS for 18 or 36 days." | 3.96 | The influence of the duration of chronic unpredictable mild stress on the behavioural responses of C57BL/6J mice. ( Brański, P; Burnat, G; Pałucha-Poniewiera, A; Podkowa, K; Rafało-Ulińska, A, 2020) |
| "As a continuation of our previous experiments, this study aimed to investigate the antidepressant- and anxiolytic-like activity of pitolisant in mice using the corticosterone-induced depression model." | 3.96 | Pitolisant protects mice chronically treated with corticosterone from some behavioral but not metabolic changes in corticosterone-induced depression model. ( Kieć-Kononowicz, K; Kotańska, M; Mika, K; Pytka, K; Sapa, J; Sałaciak, K; Wheeler, L, 2020) |
| " Considering that ketamine has significant knock-on effects, this study investigated the effects of a single coadministration with subthreshold doses of ketamine plus guanosine in a corticosterone (CORT)-induced animal model of depression and the role of anti-inflammatory and antioxidant pathways." | 3.96 | Subthreshold doses of guanosine plus ketamine elicit antidepressant-like effect in a mouse model of depression induced by corticosterone: Role of GR/NF-κB/IDO-1 signaling. ( B Zeni, AL; Camargo, A; Dalmagro, AP; M Rosa, J; P Kaster, M; S Rodrigues, AL; Tasca, CI, 2020) |
| "A total of 36 rats were randomly assigned to three groups: a normal group, model group (depression), and treatment group (depression + gentiopicroside)." | 3.91 | Metabolomic evidence for the therapeutic effect of gentiopicroside in a corticosterone-induced model of depression. ( Cui, Q; Liu, Z; Wang, C; Wang, G; Yao, T; Zhang, Q, 2019) |
| "Chronic corticosterone (CORT) stress is an anxiety and depression inducing factor that involves the dysfunction of glucocorticoid receptor (GR), brain-derived neurotrophic factor (BDNF), and neuronal plasticity." | 3.91 | Proteomic profiling of the neurons in mice with depressive-like behavior induced by corticosterone and the regulation of berberine: pivotal sites of oxidative phosphorylation. ( Du, LJ; Feng, YL; Gao, HW; Gong, Q; He, LL; Lei, F; Li, J; Luo, YY; Wang, ML; Yan, XJ; Yang, SL, 2019) |
| " In addition to contextual fear, we also measured startle reactivity, anxiety and corticosterone plasma levels of the mice." | 3.91 | Memory generalization after one-trial contextual fear conditioning: Effects of sex and neuropeptide S receptor deficiency. ( Fendt, M; Germer, J; Kahl, E, 2019) |
| " A treatment with escitalopram reversed depression-like behavior accompanied by reductions in BDNF levels in serum and the nucleus accumbens, while a treatment with blonanserin ameliorated abnormal social interaction behavior with reductions in serum BDNF levels." | 3.91 | Antidepressant activities of escitalopram and blonanserin on prenatal and adolescent combined stress-induced depression model: Possible role of neurotrophic mechanism change in serum and nucleus accumbens. ( Deriha, K; Furuse, K; Hashiguchi, H; Hashimoto, E; Ishii, T; Kawanishi, C; Kigawa, Y; Shiraishi, M; Tayama, M; Ukai, W, 2019) |
| " This study investigated antidepressant-like effects and possible underlying mechanisms of Lactobacillus paracasei PS23 (PS23), live or heat-killed, in a mouse model of corticosterone-induced depression using fluoxetine as standard drug." | 3.91 | Antidepressant-like activities of live and heat-killed Lactobacillus paracasei PS23 in chronic corticosterone-treated mice and possible mechanisms. ( Cheng, YF; Hsu, CC; Liao, CL; Tsai, YC; Wang, S; Wei, CL; Wu, CC; Yen, JT, 2019) |
| " We then measured the body weight and performed the sucrose preference test, forced swimming test (FST) and open field test to detect the effects of stress on anhedonia and activity." | 3.91 | DNA methylation of the Tacr2 gene in a CUMS model of depression. ( Fu, L; Liu, Z; Wan, Q; Wang, G; Xiang, D; Xiao, J; Xiao, L; Yao, L; Zhu, F, 2019) |
| " This study utilized a translational animal model of maternal depression (based on giving high levels of corticosterone (CORT, 40 mg/kg, s." | 3.91 | Developmental outcomes after gestational antidepressant treatment with sertraline and its discontinuation in an animal model of maternal depression. ( Brummelte, S; Kott, JM; Mooney-Leber, SM, 2019) |
| " In a mouse model of disrupted mother-infant relationship, early weaning causes long-term impacts on pups to exhibit increased corticosterone secretion, anxiety, and stress responses in their adulthood." | 3.91 | Early weaning increases anxiety via brain-derived neurotrophic factor signaling in the mouse prefrontal cortex. ( Abe, H; Hirayama, N; Ida, K; Kanbara, N; Kikusui, T; Mitsuyama, K; Mogi, K; Nagasawa, M; Ozaki, M; Tanabe, N; Tokita, M; Yoshida, M, 2019) |
| " Other studies demonstrate the roles of stathmin and corticosterone associated with fear- and anxiety-like behaviors in rodent models." | 3.91 | Affective profiling for anxiety-like behavior in a rodent model of mTBI. ( Ahlers, ST; Ciarlone, SL; Goodrich, JA; McCarron, RM; Norris, JN; Statz, JK; Tschiffely, AE; Walker, PB, 2019) |
| " To accomplish this, we monitored basal and reactive blood plasma levels of the stress hormone corticosterone in rats for ten weeks following acoustic trauma, and quantified changes in hippocampal glucocorticoid and mineralocorticoid receptors." | 3.91 | Noise-induced hearing loss alters hippocampal glucocorticoid receptor expression in rats. ( Allman, BL; Hayes, SH; Majumdar, A; Manohar, S; Salvi, R, 2019) |
| " Here, using the predator scent model of PTSD in rats and a longitudinal design, we measure pre-trauma brain-wide neural circuit functional connectivity, behavioral and corticosterone responses to trauma exposure, and post-trauma anxiety." | 3.91 | Individual variability in behavior and functional networks predicts vulnerability using an animal model of PTSD. ( Bravo-Rivera, H; Dopfel, D; Ma, Y; Perez, PD; Quirk, GJ; Verbitsky, A; Zhang, N, 2019) |
| "20(S)-Protopanaxadiol (PPD) is a basic aglycone of the dammarane triterpenoid saponins and exerts antidepressant-like effects on behaviour in the forced swimming test (FST) and tail suspension test (TST) and in rat olfactory bulbectomy depression models." | 3.91 | Antidepressant-like effects of 20(S)-protopanaxadiol in a mouse model of chronic social defeat stress and the related mechanisms. ( Huang, H; Jiang, N; Liu, XM; Lu, C; Lv, GH; Lv, JW; Wang, HX; Wang, Q; Xia, TJ; Yang, YJ, 2019) |
| "TNF-tg and wild-type (WT) animals received either vehicle or the GC corticosterone (100 μg/ml) in drinking water at onset of arthritis." | 3.91 | Therapeutic glucocorticoids prevent bone loss but drive muscle wasting when administered in chronic polyarthritis. ( Cooper, MS; Fareed, S; Fenton, CG; Goodyear, CS; Hardy, RS; Jones, R; Jones, SW; Lai, YC; Langen, R; Lavery, GG; Lewis, JW; Mackie, H; Martin, CS; Raza, K; Seabright, AP; Webster, JM; Wehmeyer, C, 2019) |
| " Also, they displayed higher levels of blood serum corticosterone, as well as decreased body weight." | 3.88 | Vicarious Social Defeat Stress Induces Depression-Related Outcomes in Female Mice. ( Alipio, JB; Braren, SH; Castillo, SA; Flores-Ramirez, FJ; Garcia-Carachure, I; Hernandez, MA; Iñiguez, SD; Lobo, MK; Riggs, LM; Sanchez, DO; Serrano, PA, 2018) |
| " In this study, we examined the molecular effects associated with a response to a week-long treatment with escitalopram in the chronic escape deficit (CED) model, a validated model of depression based on the induction of an escape deficit after exposure of rats to an unavoidable stress." | 3.88 | Molecular changes associated with escitalopram response in a stress-based model of depression. ( Alboni, S; Benatti, C; Blom, JMC; Brunello, N; Mendlewicz, J; Tascedda, F, 2018) |
| "Unilateral intrahippocampal (IH) kainic acid (KA) injections were used to elicit nonconvulsive status epilepticus (SE), epileptogenesis, and SRS, as monitored by video-electroencephalography." | 3.88 | Hepatic and hippocampal cytochrome P450 enzyme overexpression during spontaneous recurrent seizures. ( Bertaso, F; deBock, F; Espallergues, J; Fayd'Herbe De Maudave, A; Ghosh, C; Girard, B; Guérineau, NC; Marchi, N; Milman, A; Pascussi, JM; Runtz, L; Toussenot, M, 2018) |
| "Many models, such as chronic mild stress, chronic stress or chronic corticosterone injections are used to induce depression associated with cognitive deficits." | 3.88 | Combined corticosterone treatment and chronic restraint stress lead to depression associated with early cognitive deficits in mice. ( Bahane, DAN; Bum, EN; Ngoupaye, GT; Yassi, FB, 2018) |
| "We have shown previously that in ovo betaine injection can prevent nonalcoholic fatty liver induced by glucocorticoid exposure in chickens; yet it remains unknown whether feeding betaine to laying hens may exert similar effects in their progeny." | 3.88 | Corticosterone-Induced Lipogenesis Activation and Lipophagy Inhibition in Chicken Liver Are Alleviated by Maternal Betaine Supplementation. ( Abobaker, H; Hou, Z; Hu, Y; Omer, NA; Sun, Q; Zhao, R; Zong, Y, 2018) |
| " Magnolol, main constituent identified in the barks of Magnolia officinalis, exerted antidepressant effects in a rat model of depression induced by chronic unpredictable mild stress in previous studies." | 3.88 | Antidepressant effects of magnolol in a mouse model of depression induced by chronic corticosterone injection. ( Bai, Y; Dai, G; Jing, W; Ju, W; Song, L; Xu, M; Zhang, W; Zhu, L, 2018) |
| " PAE treatment also reduced expression of fatigue-related factors such as corticosterone, serotonin, and catecholamines (adrenaline and noradrenaline) in the brain and serum, and decreased expression of CD68, Ibal-1, and the inflammatory cytokines TNF-α, IL-6, and IL-1β in the brain." | 3.88 | Polygonum aviculare L. extract reduces fatigue by inhibiting neuroinflammation in restraint-stressed mice. ( Jang, S; Kim, HK; Lee, SW; Park, SD; Park, SH; Son, E; Sung, YY, 2018) |
| " Therefore, we tested this hypothesis in the depression model of chronic administration of corticosterone (CORT) in mice and treated the animals daily with liraglutide (5 or 20 nmol/kg ip." | 3.88 | Liraglutide attenuates the depressive- and anxiety-like behaviour in the corticosterone induced depression model via improving hippocampal neural plasticity. ( Birong, L; Christian, H; Feiyu, S; Le, W; Weina, H; Yuhu, N, 2018) |
| " We evaluated the acute corticosterone response to hypoxia or ACTH injection following pretreatment with GPS1574 (32 mg/kg) or vehicle for GPS1574 in PD2, PD8, and PD15 rat pups." | 3.88 | Effect of a melanocortin type 2 receptor (MC2R) antagonist on the corticosterone response to hypoxia and ACTH stimulation in the neonatal rat. ( Gehrand, AL; Goldenberg, AJ; Hoeynck, B; Jablonski, M; Raff, H; Waples, E, 2018) |
| " The present study aimed to examine effects on regional brain activity of two frequently used depression models, the chronic unpredictable mild stress (CUMS)- and the chronic corticosterone (CORT) depression model." | 3.88 | Regional alterations of cerebral [ ( Baeken, C; Brans, B; De Vos, F; Descamps, B; Dockx, R; Goethals, I; Pauwelyn, G; Peremans, K; Van Laeken, N; Vanhove, C, 2018) |
| "Elevated circulating uric acid has been postulated to play an important pathophysiological role in estrogen-progestin combined oral contraceptive (COC)-induced hypertension and endothelial dysfunction." | 3.88 | Inhibition of adenosine deaminase and xanthine oxidase by valproic acid abates hepatic triglyceride accumulation independent of corticosteroids in female rats treated with estrogen-progestin. ( Areola, ED; Badmus, OO; Kim, I; Michael, OS; Olatunji, LA; Omolekulo, TE, 2018) |
| " This study aimed to investigate the activity of RIP II in a corticosterone-induced depression mice model." | 3.88 | Riparin II ameliorates corticosterone-induced depressive-like behavior in mice: Role of antioxidant and neurotrophic mechanisms. ( Barbosa Filho, JM; Capibaribe, VCC; Chaves, RC; da Silva, DMA; de Araújo, MA; de Sousa, FCF; de Souza, AG; Gutierrez, SJC; Lopes, IS; Macêdo, DS; Oliveira, ICM; Valentim, JT, 2018) |
| " Ursolic acid, metformin, gliclazide and their combinations when administered daily for 30 days significantly improved insulin sensitivity apart from behavioral and biochemical alterations in stressed mice." | 3.88 | Synergistic action of ursolic acid and metformin in experimental model of insulin resistance and related behavioral alterations. ( Ahuja, S; Akhtar, A; Kumar, A; Mourya, A; Sah, SP, 2018) |
| "Compared with the control group, AD rats displayed significant spatial learning and reference memory impairments, serious anxiety disorders, obvious hypertrophy of adrenal gland, elevated corticosterone and ACTH levels in the plasma, and increased 11β-HSD1 activity in liver and groin fat pad." | 3.88 | Akebia saponin D reverses corticosterone hypersecretion in an Alzheimer's disease rat model. ( Jin, Y; Linhardt, RJ; Shen, J; Wang, R; Wang, Y; Yang, X; Yang, Z; Zhang, F, 2018) |
| " We used a well-characterized anxiety/depressive-like mouse model consisting of continuous input of corticosterone for seven consecutive weeks." | 3.88 | Adiporon, an adiponectin receptor agonist acts as an antidepressant and metabolic regulator in a mouse model of depression. ( Bayer, P; Béchade, C; Chabry, J; Debayle, D; Gay, AS; Guyon, A; Heurteaux, C; Maroteaux, L; Nicolas, S, 2018) |
| " The corticosterone rat model was developed to understand the influence of stress on depression-like symptomatology." | 3.88 | Depression-like behaviors induced by chronic corticosterone exposure via drinking water: Time-course analysis. ( Cui, SY; Cui, XY; Ding, H; Hu, X; Liu, YT; Ye, H; Zhang, YH; Zhao, HL, 2018) |
| " Furthermore, without affecting the transcription of hepatic gluconeogenic enzymes, adrenalectomy causes exhaustion of hepatic glycogen and insulin-independent lethal hypoglycemia upon infection." | 3.88 | Adrenal hormones mediate disease tolerance in malaria. ( Chapman, KE; De Bosscher, K; De Geest, C; Kenyon, CJ; Knoops, S; Lays, N; Opdenakker, G; Pham, TT; Schuit, F; Van den Steen, PE; Van der Molen, K; Vandermosten, L; Verma, M, 2018) |
| " This study aims to investigate the potential effects of hydrogen-rich saline (HRS) administration on naloxone-precipitated withdrawal symptoms and morphine withdrawal-induced anxiety-like behaviors." | 3.85 | Hydrogen-rich saline attenuates anxiety-like behaviors in morphine-withdrawn mice. ( Cong, B; Gong, M; Guo, H; Hui, R; Ma, C; Shen, Q; Wang, J; Wen, D; Zhao, P, 2017) |
| "Administration of the acidic solution potentiated dentin hypersensitivity and increased corticosterone levels in the ED group compared with the WD group." | 3.85 | Depressive behavior induced by unpredictable chronic mild stress increases dentin hypersensitivity in rats. ( Barbosa, FM; Bonamin, LV; Bondan, EF; Cabral, D; de Fátima Monteiro Martins, M; Kabadayan, F; Kirsten, TB; Martha Bernardi, M; Queiroz-Hazarbassanov, N; Saraceni, CHC, 2017) |
| "Objective To establish a postpartum depression animal model induced by pre-pregnancy stress,assess abnormal maternal depressive-like behavior,observe the expression of disrupted-in-schizophrenia 1 (DISC1) in the hippocampus,and detect serum estradiol and corticosterone." | 3.85 | Expression of Disrupted-in-schizophrenia 1 in Hippocampus in Postpartum Depression Animal Models Induced by Pre-pregnancy Stress. ( Chen, C; Chen, G; Tao, W; Wu, H; Xia, B; Zhang, H; Zhou, X, 2017) |
| " Compared to virgin females, pregnancy increases allopregnanolone levels in group-housed as well as isolated dams and such increase was greater in the latter group." | 3.85 | Juvenile social isolation affects maternal care in rats: involvement of allopregnanolone. ( Biggio, F; Boero, G; Concas, A; Congiu, M; Corda, D; Garau, A; Pisu, MG; Porcu, P; Serra, M, 2017) |
| "To further explore the underlying antidepressant mechanism of ginseng total saponins (GTS), this study observed the effects on hippocampal astrocyte structural plasticity and hippocampal volume in the corticosterone-induced mouse depression model." | 3.85 | Preventive Effects of Ginseng Total Saponins on Chronic Corticosterone-Induced Impairment in Astrocyte Structural Plasticity and Hippocampal Atrophy. ( Chen, L; Dai, JG; Huang, YF; Lin, ZX; Wang, X; Zhao, YN, 2017) |
| "Both treatments induced obesity but only Ob-MSG showed altered behavioral parameters, which is related to increased concentration of corticosterone and hypothalamic ERK1 and 2 activation." | 3.85 | Altered behavior of adult obese rats by monosodium l-glutamate neonatal treatment is related to hypercorticosteronemia and activation of hypothalamic ERK1 and ERK2. ( Andreazzi, AE; de Caires Júnior, LC; de Freitas Mathias, PC; Gonçalves, CF; González Garcia, RM; Guimarães, ED; Macedo de Almeida, M; Mourao-Júnior, CA; Musso, CM; Paes, ST; Pettersen, KG; Torrezan, R, 2017) |
| " Fecal pellets and serum corticosterone (CORT) levels were measured as an index of anxiety." | 3.85 | Impact of Psychological Stress on Pain Perception in an Animal Model of Endometriosis. ( Appleyard, CB; Cruz, ML; Hernandez, S; Seguinot, II; Torres-Reveron, A, 2017) |
| " We investigated whether neonatal blockade of the GABA-A receptors by bicuculline can alter anxiety- and depression-like behaviors, body weight, food intake, corticosterone and testosterone levels in adult mice (postnatal days 80-95)." | 3.85 | Neonatal blockade of GABA-A receptors alters behavioral and physiological phenotypes in adult mice. ( Amani, M; Salari, AA, 2017) |
| " This investigation addressed the hypothesis that topical 5α-tetrahydrocorticosterone (5αTHB, a corticosterone metabolite) inhibits dermal inflammation without affecting processes responsible for skin thinning and impaired wound healing." | 3.85 | Safer topical treatment for inflammation using 5α-tetrahydrocorticosterone in mouse models. ( Abernethie, AJ; Andrew, R; Gastaldello, A; Hadoke, PW; Livingstone, DE; Tsang, N; Walker, BR, 2017) |
| " We recently demonstrated that adult male rats exposed to low doses of corticosterone during lactation (CORT-nursed rats) are protected against experimental colitis induced by the intracolonic infusion of 2,4,6-trinitrobenzenesulfonic acid (TNBS)." | 3.85 | Maternal exposure to low levels of corticosterone during lactation protects adult rat progeny against TNBS-induced colitis: A study on GR-mediated anti-inflammatory effect and prokineticin system. ( Broccardo, M; Canu, N; Casolini, P; Fusco, I; Giuli, C; Lattanzi, R; Marconi, V; Petrella, C; Severini, C; Theodorou, V; Zinni, M; Zuena, AR, 2017) |
| "Ketamine has emerged as a novel strategy to treat refractory depression, producing rapid remission, but elicits some side effects that limit its use." | 3.83 | Creatine, Similar to Ketamine, Counteracts Depressive-Like Behavior Induced by Corticosterone via PI3K/Akt/mTOR Pathway. ( Colla, AR; Cunha, MP; Lieberknecht, V; Oliveira, Á; Pazini, FL; Rodrigues, AL; Rosa, JM, 2016) |
| "This study was designed to investigate the effectiveness of nisoldipine, an L-type voltage-sensitive calcium channel blocker, to ameliorate anxiety and fear response in a mouse model of post-traumatic stress disorder (PTSD)." | 3.83 | Investigating the role of nisoldipine in foot-shock-induced post-traumatic stress disorder in mice. ( Bali, A; Jaggi, AS; Singh, N; Verma, M, 2016) |
| "Neuropeptide Y (NPY) was recently proposed to be associated with stress and airway inflammation; however, this has rarely been studied in animal models of asthma." | 3.83 | An association between neuropeptide Y levels and leukocyte subsets in stress-exacerbated asthmatic mice. ( Ho, RC; Lu, Y, 2016) |
| " Here we used a rodent model of anxiety/depression-like states, which is based on chronic CORT administration and studied the effects of the antidepressant fluoxetine (FLX) on behavior, olfaction, and adult neurogenesis in the dentate gyrus (DG), olfactory bulb (OB), and the olfactory epithelium (OE)." | 3.83 | Anxiety- and Depression-Like States Lead to Pronounced Olfactory Deficits and Impaired Adult Neurogenesis in Mice. ( de Chaumont, F; Denizet, M; Gabellec, MM; Guilloux, JP; Lazarini, F; Lledo, PM; Olivo-Marin, JC; Siopi, E, 2016) |
| "Previously published reports have revealed the antidepressant-like effects of icariin in a chronic mild stress model of depression and in a social defeat stress model in mice." | 3.83 | Icariin reverses corticosterone-induced depression-like behavior, decrease in hippocampal brain-derived neurotrophic factor (BDNF) and metabolic network disturbances revealed by NMR-based metabonomics in rats. ( Gong, MJ; Han, B; Liang, SW; Wang, SM; Zou, ZJ, 2016) |
| "The anxiety status is changed along with memory impairments in intracerebroventricular colchicine injected rat model of Alzheimer Disease (cAD) due to neurodegeneration, which has been indicated to be mediated by inflammation." | 3.83 | Cox-2 Plays a Vital Role in the Impaired Anxiety Like Behavior in Colchicine Induced Rat Model of Alzheimer Disease. ( Ghosh, T; Sil, S, 2016) |
| " We found high anxiety levels and poor maternal care along with reduced serum prolactin and increased corticosterone levels in dams following maternal trauma (MT)." | 3.83 | Effects of In utero environment and maternal behavior on neuroendocrine and behavioral alterations in a mouse model of prenatal trauma. ( Canneva, F; Distler, J; Freitag, CM; Frey, S; Funke, R; Golub, Y; Kratz, O; Moll, GH; Solati, J; von Hörsten, S, 2016) |
| " We used several well-validated animal models of depression to assess the antidepressant-like activity of LPM580153, followed by a neurotransmitter uptake assay and a corticosterone-induced cell injury model to explore its mechanism of action." | 3.83 | Antidepressant-like Effects of LPM580153, A Novel Potent Triple Reuptake Inhibitor. ( Liu, Q; Meng, X; Shao, J; Tian, J; Wang, H; Ye, L; Zhang, F; Zhong, Y, 2016) |
| " Since the BDNF hypothesis of depression postulates that a reduction in BDNF is directly involved in the pathophysiology of depression, we evaluated the anti-depressive effects of HMF in mice with subcutaneously administered corticosterone at a dose of 20 mg/kg/day for 25 days." | 3.83 | 3,5,6,7,8,3',4'-Heptamethoxyflavone, a Citrus Flavonoid, Ameliorates Corticosterone-Induced Depression-like Behavior and Restores Brain-Derived Neurotrophic Factor Expression, Neurogenesis, and Neuroplasticity in the Hippocampus. ( Amakura, Y; Furukawa, Y; Nakajima, M; Okuyama, S; Sawamoto, A; Yamamoto, K; Yoshimura, M, 2016) |
| " In this study, we used the chronic corticosterone (CORT)-induced mouse model of anxiety/depression to assess antidepressant-like effects of baicalin and illuminate possible molecular mechanisms by which baicalin affects GR-mediated hippocampal neurogenesis." | 3.83 | Baicalin promotes hippocampal neurogenesis via SGK1- and FKBP5-mediated glucocorticoid receptor phosphorylation in a neuroendocrine mouse model of anxiety/depression. ( Dong, Y; Ma, J; Pan, X; Su, G; Wang, F; Wu, C; Yang, J; Zhang, K, 2016) |
| " Here we investigate the short- and long-term effects of adolescent chronic mild stress (CMS) on the emergence of anxiety-/depressive-like behaviors (open-field and forced swim test - FST) and on HPA activity (corticosterone and type 1 CRH receptor - CRHR1) in PAE male and female rats." | 3.83 | Short- and long-term effects of stress during adolescence on emotionality and HPA function of animals exposed to alcohol prenatally. ( Chew, L; Ellis, L; Mok, P; Raineki, C; Weinberg, J, 2016) |
| " As adults, fear/anxiety behaviors were assessed, and animals were subjected to an asthma model induced by ovalbumin." | 3.83 | Protective effect of early prenatal stress on the induction of asthma in adult mice: Sex-specific differences. ( Campos, NE; da Cunha, AA; de Souza, RG; Donadio, MV; Nuñez, NK; Pitrez, PM; Vargas, MH, 2016) |
| "It suggested that HCPE could improve the depression-like emotional status and associated cognitive deficits in CUMS rats, which might be mediated by regulation of neurotransmitters and BDNF levels in brain, alleviation of corticosterone level as well as the alleviation of oxidative stress." | 3.83 | Antidepressant-like effects and cognitive enhancement of the total phenols extract of Hemerocallis citrina Baroni in chronic unpredictable mild stress rats and its related mechanism. ( Aibai, S; Dong, LM; Le Zhai, J; Liao, YH; Liu, XM; Lu, C; Wang, KZ; Xu, P; Yang, Y, 2016) |
| "05) the increase in immobility period, anxiety, spleen weight, BUN and LDH levels, and MDA levels along with decrease in grip strength, locomotor activity, plasma corticosterone, adrenal gland weight, catalase, and GSH." | 3.83 | Investigation of the effects of vanilloids in chronic fatigue syndrome. ( Goswami, S; Sarvaiya, K, 2016) |
| "The aim of the present study was to investigate the effects of the selective agonists of the corticotropin-releasing factor (CRF) 2 receptor, urocortin 2 (UCN 2) and urocortin 3 (UCN 3), on the anxiety- and depression-like signs induced by acute nicotine withdrawal in mice." | 3.83 | Selective CRF2 receptor agonists ameliorate the anxiety- and depression-like state developed during chronic nicotine treatment and consequent acute withdrawal in mice. ( Bagosi, Z; Balangó, B; Bokor, P; Buzás, A; Csabafi, K; Jászberényi, M; Palotai, M; Pintér, D; Simon, B; Szabó, G, 2016) |
| " pharmacological (Scopolamine-induced and corticosterone-induced), Environmental (Aluminium-induced and noise-stress) and physiological (natural aging) models in rats in a single experimental study across three cognitive domains spatial, recognition, and associative memory and associated alterations in their oxidative status and neurochemical profile to select appropriate dementia model." | 3.83 | Scopolamine-induced greater alterations in neurochemical profile and increased oxidative stress demonstrated a better model of dementia: A comparative study. ( Haider, S; Perveen, T; Tabassum, S, 2016) |
| " MEC prevented CRS-induced depressive-like behavior via increasing sucrose preference, body weight, and forced swim test (FST) struggling and swimming while reducing immobility in FST and hypothalamic-pituitary-adrenal (HPA) axis hyperactivity (adrenal gland weight and serum corticosterone)." | 3.81 | Behavioral effects of nicotinic antagonist mecamylamine in a rat model of depression: prefrontal cortex level of BDNF protein and monoaminergic neurotransmitters. ( Aboul-Fotouh, S, 2015) |
| " The impact of these housing conditions was assessed during adulthood by measuring weight gain, quantifying voluntary ethanol intake, measuring plasma corticosterone levels, and assessing anxiety-like behavior." | 3.81 | Impact of social isolation and enriched environment during adolescence on voluntary ethanol intake and anxiety in C57BL/6J mice. ( Laber, K; Lopez, MF, 2015) |
| " We analysed the time course of the global withdrawal score, the anxiety-like effects, monoamine concentrations, the brain-derived neurotrophic factor (BDNF) expression, the corticosterone plasmatic levels and [(3)H]epibatidine binding sites during NIC withdrawal precipitated by mecamylamine, a nicotinic receptor antagonist (MEC)." | 3.81 | Lack of GABAB receptors modifies behavioural and biochemical alterations induced by precipitated nicotine withdrawal. ( Antonelli, MC; Balerio, GN; Bettler, B; Machado, LM; Pedrón, VT; Varani, AP, 2015) |
| " The present study investigated the effects of chronic stress before, after, and during learning on the changes of learning and memory, on serum and hippocampal levels of corticosterone (CORT), brain-derived neurotrophic factor (BDNF) and body weight in rats." | 3.81 | Effects of different timing of stress on corticosterone, BDNF and memory in male rats. ( Alaei, H; Hosseini, N; Radahmadi, M; Sharifi, MR, 2015) |
| "The aim of this study was to determine the effects of previous administration of metyrapone (met) on the acute lung injury (ALI) induced by caecal ligation and puncture (CLP) and to explore met's relationship with endogenous glucocorticoids (GCs) as measured by inflammatory, oxidative and functional parameters." | 3.81 | Inhibition of endogenous glucocorticoid synthesis aggravates lung injury triggered by septic shock in rats. ( Incerpi, EK; Oliveira, LM; Pereira, EM; Soncini, R, 2015) |
| "In this study, we sought to determine whether resveratrol (RSV), a nonhormonal compound, would suppress the myometrial infiltration, improve pain behavior, lower stress level, improve the expression of some proteins known to be involved in adenomyosis, and reduce uterine contractility in a mice model of adenomyosis." | 3.81 | Resveratrol Reduces Myometrial Infiltration, Uterine Hyperactivity, and Stress Levels and Alleviates Generalized Hyperalgesia in Mice With Induced Adenomyosis. ( Chen, Y; Guo, SW; Liu, X; Zhang, H; Zhu, B, 2015) |
| "The present study focuses on detecting anxiety-like behavior and associated neurochemical alterations in adolescent rats exposed perinatally to bisphenol A (BPA), an estrogen-mimicking endocrine disrupter and investigating the possible involvement of metabotropic glutamate 2/3 receptors (mGlu2/3 receptors) in BPA-induced anxiogenic effects." | 3.81 | Perinatal exposure to low-dose of bisphenol A causes anxiety-like alteration in adrenal axis regulation and behaviors of rat offspring: a potential role for metabotropic glutamate 2/3 receptors. ( Chen, F; Chen, L; Feng, X; Li, Y; Zhou, L; Zhou, R, 2015) |
| " Hypericin (HY) is the main components in SJW extracts, which is used to treat fatigue, weakness, and mild depression." | 3.81 | LC-MS/MS based studies on the anti-depressant effect of hypericin in the chronic unpredictable mild stress rat model. ( Chen, C; Chen, F; Lu, YN; Zhai, XJ; Zhu, CR, 2015) |
| "Repeated injection of corticosterone (CORT) induces dysregulation in the hypothalamic-pituitary-adrenal (HPA) axis, resulting in depression." | 3.81 | Angelica gigas ameliorate depression-like symptoms in rats following chronic corticosterone injection. ( Hahm, DH; Lee, B; Lee, H; Shim, I; Sur, B, 2015) |
| " In the present study, animals exposed to the chronic unpredictable stress (CUS), a rodent model of depression, exhibited elevated corticosterone, depressive-like behavior, memory deficits, accompanied with decreased cAMP-PKA-CREB and cAMP-ERK1/2-CREB signaling and neuroplasticity." | 3.81 | Phosphodiesterase-4D Knock-down in the Prefrontal Cortex Alleviates Chronic Unpredictable Stress-Induced Depressive-Like Behaviors and Memory Deficits in Mice. ( Li, YF; Liu, YQ; O'Donnell, JM; Wang, ZZ; Wilson, SP; Xu, Y; Yang, WX; Zhang, HT; Zhang, Y; Zhang, YZ; Zhao, N, 2015) |
| " In addition, despite comparable corticosterone levels, corticosteroid binding globulin levels were lower in Harlan compared with Charles River rats in the absence of inflammation, suggesting that a lower corticosterone reservoir in Harlan rats may underlie their greater susceptibility to inflammation." | 3.81 | Colony-Specific Differences in Endocrine and Immune Responses to an Inflammatory Challenge in Female Sprague Dawley Rats. ( Bodnar, TS; Hammond, GL; Hill, LA; Soma, KK; Taves, MD; Weinberg, J; Yu, W, 2015) |
| " This study was carried out in order to assess the influence of neonatal tactile stimulation (TS) on behavioral and morphological responses related to depression-like and anxiety-like behaviors, assessed following the administration of sertraline (SERT), a selective serotonin re-uptake inhibitor (SSRI)." | 3.81 | Neonatal tactile stimulation decreases depression-like and anxiety-like behaviors and potentiates sertraline action in young rats. ( Antoniazzi, CT; Barcelos, RC; Burger, ME; Duarte, MM; Duarte, T; Freitas, D; Metz, VG; Segat, HJ; Vey, LT, 2015) |
| " Dependent measures included tests utilizing object recognition (OR), Y-maze, elevated plus maze (EPM), forced swim (FST), blood alcohol content, corticosterone levels, and body weights." | 3.80 | Female rats exposed to stress and alcohol show impaired memory and increased depressive-like behaviors. ( Gomez, JL; Luine, VN, 2014) |
| "In this study, a mouse model of anxiety/depressant-like behavior induced by long-term corticosterone treatment was used to evaluate behavioral, endocrinal, and neurochemical changes in mice and their possible modulation of F-DPS treatment." | 3.80 | An organoselenium compound improves behavioral, endocrinal and neurochemical changes induced by corticosterone in mice. ( Bortolatto, CF; Duarte, MM; Gai, BM; Heck, SO; Nogueira, CW; Stein, AL; Zeni, G, 2014) |
| " Herein, we have described a mouse model of a depression-like and insulin-resistant (DIR) state induced by the co-treatment of high-fat diet (HFD) and corticosterone (CORT)." | 3.80 | Depression-like behaviors in mice subjected to co-treatment of high-fat diet and corticosterone are ameliorated by AICAR and exercise. ( Ji, L; Li, H; Liu, W; Zhai, X, 2014) |
| " We investigated for the first time whether neonatal exposure to TNF-α can affect body weight, stress-induced corticosterone (COR), anxiety- and depression-related behaviors in adult mice." | 3.80 | Tumor necrosis factor-alpha during neonatal brain development affects anxiety- and depression-related behaviors in adult male and female mice. ( Babri, S; Doosti, MH; Salari, AA, 2014) |
| " Anxiety was evaluated by the elevated plus maze model and by serum corticosterone levels." | 3.80 | Dentin hypersensitivity induces anxiety and increases corticosterone serum levels in rats. ( Bergamini, MR; Bernardi, MM; Ciaramicoli, MT; Kabadayan, F; Kodama, RM; Saraceni, CH; Sufredini, IB, 2014) |
| "Intermittent hypoxia (IH) is an animal model of apnea-induced hypoxia, a common stressor in the premature neonate." | 3.80 | Programming of the hypothalamic-pituitary-adrenal axis by neonatal intermittent hypoxia: effects on adult male ACTH and corticosterone responses are stress specific. ( Bruder, ED; Chintamaneni, K; Raff, H, 2014) |
| "An overproduction of corticosterone during severe sepsis results in increased apoptosis of immune cells, which may result in relative immunosuppression and an impaired ability to fight infections." | 3.80 | Selective histone deacetylase-6 inhibition attenuates stress responses and prevents immune organ atrophy in a lethal septic model. ( Alam, HB; Bronson, RT; Li, Y; Liu, B; Velmahos, GC; Zhao, T, 2014) |
| " In this study, we investigated the antidepressant effect of GTS on the corticosterone-induced mouse depression model and explored the underlying mechanism." | 3.80 | The antidepressant effects of ginseng total saponins in male C57BL/6N mice by enhancing hippocampal inhibitory phosphorylation of GSK-3β. ( Chen, L; Dai, J; Huang, Y; Wang, Z; Zhang, H; Zhao, Y, 2014) |
| "Female rats implanted with 28-day osmotic minipumps delivering the SSRI escitalopram throughout pregnancy had serum escitalopram concentrations in a clinically observed range (17-65 ng/ml)." | 3.79 | Prenatal exposure to escitalopram and/or stress in rats: a prenatal stress model of maternal depression and its treatment. ( Boss-Williams, KA; Bourke, CH; Capello, CF; Owens, MJ; Rogers, SM; Stowe, ZN; Weiss, JM; Yu, ML, 2013) |
| "Ablation of olfactory bulbs caused depression-like symptoms as evidenced by increased immobility time in FST, hyperactivity in open field arena, and anhedonic like response in SPT along with alterations in mitochondrial enzyme complexes, increased serum corticosterone levels and oxidative damage." | 3.79 | Suppression of neuroinflammatory and apoptotic signaling cascade by curcumin alone and in combination with piperine in rat model of olfactory bulbectomy induced depression. ( Garg, S; Kumar, A; Rinwa, P, 2013) |
| " Moreover these rats exhibited anhedonia in a sucrose consumption test, and increased grooming in the open-field test, which reflects an anxiety-like condition." | 3.79 | Disruption of circadian rhythms due to chronic constant light leads to depressive and anxiety-like behaviors in the rat. ( Angeles-Castellanos, M; Escobar, C; Salgado-Delgado, R; Tapia-Osorio, A, 2013) |
| "Corticosterone (CORT) and other glucocorticoids cause peripheral insulin resistance and compensatory increases in β-cell mass." | 3.79 | Exogenous glucocorticoids and a high-fat diet cause severe hyperglycemia and hyperinsulinemia and limit islet glucose responsiveness in young male Sprague-Dawley rats. ( Beaudry, JL; D'souza, AM; Riddell, MC; Teich, T; Tsushima, R, 2013) |
| "The antidepressant effect of a compound formed by co-ultramicronized palmitoylethanolamide (PEA) and luteolin (PEA+luteolin) was investigated in a mouse model of anxiety/depressive-like behavior." | 3.79 | Effects of palmitoylethanolamide and luteolin in an animal model of anxiety/depression. ( Ahmad, A; Campolo, M; Crupi, R; Cuzzocrea, S; Esposito, E; Paterniti, I, 2013) |
| " Heart weight/body weight ratio, left ventricle/body weight ratio, heart length, plasma corticosterone levels, and plasma troponin I levels of intruder rats were significantly higher as compared to control rats." | 3.79 | An animal model of stress-induced cardiomyopathy utilizing the social defeat paradigm. ( Cierniak, KH; Moravec, CS; Murphy, HM; Sweet, WE; Wideman, CH, 2013) |
| " In this study, we investigated whether male mice with a genetic predisposition for high-reactivity (HR), intermediate-reactivity (IR), or low-reactivity (LR) stress-induced corticosterone (CORT) secretion present different levels of free CORT and CORT-binding proteins, basally and in response to stressors of different intensity." | 3.79 | Corticosteroid-binding globulin contributes to the neuroendocrine phenotype of mice selected for extremes in stress reactivity. ( Heinzmann, JM; Helbling, JC; Mattos, GE; Minni, AM; Moisan, MP; Norkowski, S; Touma, C, 2013) |
| " In the present study, we compared endogenous corticosterone production of wild-type (WT) and TLR2-deficient (TLR2) mice and analyzed survival after hydrocortisone therapy during sepsis induced by cecal ligation and puncture (CLP)." | 3.79 | Hydrocortisone reduces the beneficial effects of toll-like receptor 2 deficiency on survival in a mouse model of polymicrobial sepsis. ( Bergt, S; Butschkau, A; Heidrich, M; Nöldge-Schomburg, GE; Roesner, JP; Vollmar, B; Wagner, NM, 2013) |
| " Melatonin therapy significantly reduced the thermoregulatory deficit, brain inflammation, ischemia, oxidative damage, hypothalamic-pituitary-adrenal axis impairment, multiple organ dysfunction, and lethality caused by heat stroke." | 3.79 | Melatonin improves outcomes of heatstroke in mice by reducing brain inflammation and oxidative damage and multiple organ dysfunction. ( Hsu, SF; Lin, CH; Lin, MT; Tian, YF, 2013) |
| " At the end of the diet regimen, we assessed anxiety and depressive-like behaviour, corticosterone levels and biochemical changes in the midbrain and limbic brain regions." | 3.79 | Diet-induced obesity promotes depressive-like behaviour that is associated with neural adaptations in brain reward circuitry. ( Fulton, S; Sharma, S, 2013) |
| " This study examined the effects of mGlu2/3 receptor antagonists in chronic corticosterone-treated mice which could be used as an animal model of depression." | 3.79 | Metabotropic glutamate 2/3 receptor antagonists improve behavioral and prefrontal dopaminergic alterations in the chronic corticosterone-induced depression model in mice. ( Ago, Y; Araki, R; Baba, A; Chaki, S; Hashimoto, H; Hiramatsu, N; Kawasaki, T; Kita, Y; Matsuda, T; Nakazato, A; Onoe, H; Takuma, K; Yano, K, 2013) |
| " The present study was designed to monitor effects of injected leptin on immobilization stress-induced anorexia, behavioral deficits, and plasma corticosterone secretion in rats." | 3.79 | Inhibition of immobilization stress-induced anorexia, behavioral deficits, and plasma corticosterone secretion by injected leptin in rats. ( Akbar, N; Haleem, DJ; Haleem, MA; Haque, Z; Yasmin, F, 2013) |
| "We investigated the effect of two well characterized preclinical animal models of depression - repeated injections of corticosterone (CORT) and repeated restraint stress - on markers of GABAergic and glutamatergic activity in the hippocampus and amygdala." | 3.79 | Altered GABAergic and glutamatergic activity within the rat hippocampus and amygdala in rats subjected to repeated corticosterone administration but not restraint stress. ( Caruncho, HJ; Kalynchuk, LE; Lussier, AL; Romay-Tallón, R, 2013) |
| " oAβ(25-35) injection did not affect general activity and temperature rhythms after 6 weeks, but decreased body weight, induced short- and long-term memory impairments, increased corticosterone plasma levels, brain oxidative (lipid peroxidation), mitochondrial (caspase-9 levels) and reticulum stress (caspase-12 levels), astroglial and microglial activation." | 3.79 | Alzheimer's disease related markers, cellular toxicity and behavioral deficits induced six weeks after oligomeric amyloid-β peptide injection in rats. ( Blayo, C; Brureau, A; Delair, B; Givalois, L; Ixart, G; Keller, E; Marchal, S; Maurice, T; Zussy, C, 2013) |
| " The purpose of this study was to evaluate sexual behavior in female rats submitted to pilocarpine-induced status epilepticus (SE)." | 3.79 | Sexual response in female rats with status epilepticus. ( Alvarenga, TA; Amado, D; Andersen, ML; Cavalheiro, EA; Matos, G; Scorza, FA; Tufik, S, 2013) |
| "Several clinical reports have postulated a beneficial effect of the addition of a low dose of risperidone to the ongoing treatment with antidepressants in treatment-resistant depression." | 3.78 | Effect of co-treatment with fluoxetine or mirtazapine and risperidone on the active behaviors and plasma corticosterone concentration in rats subjected to the forced swim test. ( Gądek-Michalska, A; Kabziński, M; Rachwalska, P; Rogóż, Z; Sadaj, W, 2012) |
| " Corticosterone level and anxiety behavior revealed a stress response which was associated with a decrease of body weight, after 21-day of centrifugation at 3G but not at 2G." | 3.78 | Stress response and humoral immune system alterations related to chronic hypergravity in mice. ( Baatout, S; Bojados, M; Derradji, H; Frippiat, JP; Guéguinou, N; Jamon, M; Legrand-Frossi, C; Tschirhart, E, 2012) |
| " We created an animal model of postpartum stress/depression based on administering high levels of corticosterone (CORT) to the dams during the postpartum period which caused behavioral changes and reduced hippocampal cell proliferation in the offspring." | 3.78 | Gestational and postpartum corticosterone exposure to the dam affects behavioral and endocrine outcome of the offspring in a sexually-dimorphic manner. ( Brummelte, S; Galea, LA; Lieblich, SE, 2012) |
| " Ten days of restraint increased light compartment exploration, reduced body weight and sensitized the corticosterone response to swim stress." | 3.78 | Pharmacological modulation of stress-induced behavioral changes in the light/dark exploration test in male C57BL/6J mice. ( Fitzgerald, PJ; Hefner, KR; Holmes, A; Ihne, JL, 2012) |
| "Sub-chronic tryptophan depletion (SCTD) is proposed as an animal model for depression." | 3.78 | Sub-chronic dietary tryptophan depletion--an animal model of depression with improved face and good construct validity. ( Bermudez, I; Franklin, M; Gaburro, S; Murck, H; Singewald, N, 2012) |
| " This study aimed to examine the antidepressant-like effect and the possible mechanisms of total glycosides of peony (TGP) in the CORT-induced depression model in rats." | 3.78 | Peony glycosides reverse the effects of corticosterone on behavior and brain BDNF expression in rats. ( Che, CT; Huang, Z; Ip, SP; Mao, QQ; Xian, YF, 2012) |
| " These include reduced body weight, a facial deformity resulting from localised epidermal hyperplasia, a motor coordination deficit, alterations in exploratory activity and, in response to specific stress-inducing stimuli; a novel audible vocalisation and increased serum corticosterone." | 3.78 | Mutation of Gtf2ird1 from the Williams-Beuren syndrome critical region results in facial dysplasia, motor dysfunction, and altered vocalisations. ( Arthurson, GJ; Du, X; Hannan, AJ; Hardeman, EC; Howard, ML; Palmer, SJ; Pang, TY; Renoir, T; Spitzer, MW; Taylor, KM, 2012) |
| "Both chronic mild stress and an injection of corticosterone induce depression-like states in rodents." | 3.78 | Corticosterone reduces brain mitochondrial function and expression of mitofusin, BDNF in depression-like rodents regardless of exercise preconditioning. ( Liu, W; Zhou, C, 2012) |
| "6-fold increase in the expression of ICAM-1 and leukocyte migration at the mesentery, a 70% reduction in the serum corticosterone level and pronounced leukopenia." | 3.78 | Paradoxical effects of brain death and associated trauma on rat mesenteric microcirculation: an intravital microscopic study. ( Correia, Cde J; Cruz, JW; Kase, M; Menegat, L; Moreira, LF; Sannomiya, P; Silva, IA; Simas, R; Zanoni, FL, 2012) |
| "On the basis of CMS-induced changes of sucrose intake, a reliable measure for anhedonia, rats were divided into "resilient" and "anhedonic" groups." | 3.78 | Chronic mild stress-induced depression-like symptoms in rats and abnormalities in catecholamine uptake in small arteries. ( Aalkjaer, C; Boedtkjer, DB; Bouzinova, EV; Broegger, T; Matchkov, VV; Møller-Nielsen, N; Wiborg, O, 2012) |
| "Tolerance to morphine analgesia following repeated administration disturbs the continuation of opioid therapy for severe pain." | 3.78 | Inhibition of morphine tolerance is mediated by painful stimuli via central mechanisms. ( Fukazawa, Y; Iwai, S; Kiguchi, N; Kishioka, S; Kobayashi, Y; Saika, F; Ueno, K; Yamamoto, C, 2012) |
| " In the present study, pain sensitivity was assessed in a mouse model of anxiety/depression on the basis of chronic corticosterone (CORT) administration through the drinking water (CORT model)." | 3.78 | Antinociceptive effects of fluoxetine in a mouse model of anxiety/depression. ( Coudoré, F; David, DJ; Gardier, AM; Guiard, BP; Hache, G; Le Dantec, Y; Orvoën, S, 2012) |
| "Corticosterone plasma levels, locomotor activity, adrenal gland weight and bone loss were increased in periodontitis and stress groups, and there was also less weight gain." | 3.78 | Anti-inflammatory effect of the endocannabinoid anandamide in experimental periodontitis and stress in the rat. ( De Laurentiis, A; Elverdin, JC; Rettori, E; Rettori, V; Zorrilla Zubilete, M, 2012) |
| "The aim of the experiment was to assess the effects of an acutely administered corticosterone on the expression of GABA-A receptor alpha-2 subunits in the brain structures of high (HR) and low (LR) anxiety rats (divided according to their conditioned fear-induced freezing response) subjected to a second conditioned fear session (1 week after fear conditioning)." | 3.78 | Corticosterone attenuates conditioned fear responses and potentiates the expression of GABA-A receptor alpha-2 subunits in the brain structures of rats selected for high anxiety. ( Lehner, M; Maciejak, P; Płaźnik, A; Skórzewska, A; Sobolewska, A; Szyndler, J; Turzyńska, D; Wisłowska-Stanek, A, 2012) |
| " Both the females that cohabited with the stressed males and those that cohabited with their male offspring showed behavioral (including anxiety- and depression-like behaviors), physiological (decreased body weight and basal corticosterone levels) and neurobiological symptoms (increased activity in dorsal raphe serotonergic neurons in response to an unfamiliar male) resembling the alterations described in abused and depressed women." | 3.78 | Evidence for biological roots in the transgenerational transmission of intimate partner violence. ( Ansermet, F; Cordero, MI; Fontana, X; Marquez, C; Poirier, GL; Salehi, B; Sandi, C; Veenit, V, 2012) |
| " In order to examine the involvement of nitric oxide (NO) on stress-induced neurobehavioral changes and the concomitant alterations of neuroendocrinological factors, we studied the effects of the nonselective NOS inhibitor, N(ω)-Nitro L-arginine methyl ester hydrochloride (L-NAME) and the specific neuronal NOS inhibitor, 7-nitroindazole (7-NI) on restraint stress-induced anxiety in the elevated plus maze (EPM) test and biochemical analysis." | 3.78 | The differential role of NOS inhibitors on stress-induced anxiety and neuroendocrine alterations in the rat. ( Her, S; Joung, HY; Jung, EY; Kim, K; Lee, MS; Shim, I, 2012) |
| "We examined a potential two-hit murine animal model of depression by assessing whether a genetic deficit in reelin increases vulnerability to the depressogenic effects of the stress hormone corticosterone." | 3.77 | Reelin as a putative vulnerability factor for depression: examining the depressogenic effects of repeated corticosterone in heterozygous reeler mice. ( Caruncho, HJ; Kalynchuk, LE; Lussier, AL; Romay-Tallón, R, 2011) |
| " We recently developed a lentivirus (LV) vector that produces an insulin receptor (IR) antisense RNA sequence (IRAS) that when injected into the hypothalamus selectively decreases IR signaling in hypothalamus, resulting in increased body weight, peripheral adiposity and plasma leptin levels." | 3.77 | Obesity/hyperleptinemic phenotype adversely affects hippocampal plasticity: effects of dietary restriction. ( Evans, AN; Grillo, CA; Macht, VA; Mott, DD; Piroli, GG; Reagan, LP; Sakai, RR; Scott, KA; Wilson, SP, 2011) |
| " Subordinate 129SvEv mice showed body weight gain, hyperphagia, increased adipose fat pads weight and basal plasma corticosterone." | 3.77 | Vulnerability to chronic subordination stress-induced depression-like disorders in adult 129SvEv male mice. ( Bartolomucci, A; Ceresini, G; Dadomo, H; Di Cristo, L; Lori, A; Malinge, I; Palanza, P; Parmigiani, S; Sanghez, V; Sheardown, M, 2011) |
| " The present study was designed to investigate the effect of Hypericum perforatum treatment in a mouse model of anxiety/depressive-like behavior, induced by chronic corticosterone administration." | 3.77 | Hypericum perforatum treatment: effect on behaviour and neurogenesis in a chronic stress model in mice. ( Battaglia, F; Bramanti, P; Crupi, R; Cuzzocrea, S; La Spada, G; Marino, A; Mazzon, E; Spina, E, 2011) |
| " This enigmatic observation led to the discovery that protection from acoustic trauma in older β2(-/-) mice is mainly mediated by an age-related increase of corticosterone, not disruption of efferent cholinergic transmission." | 3.77 | Old mice lacking high-affinity nicotine receptors resist acoustic trauma. ( Bao, J; Han, J; Lei, D; Lin, Z; Ohlemiller, KK; Shen, H, 2011) |
| "To observe the effects of icariin, psoralen and oleanolic acid, the three active ingredients of Yinyanghuo (Herba Epimedii Brevicornus), Buguzhi (Fructus Psoraleae) and Nuzhenzi (Fructus Ligustri Lucidi), respectively, on gene expression profile of bone marrow stromal cells (BMSCs) from rats with corticosterone-induced osteoporosis." | 3.77 | [Effects of active ingredients in three kidney-tonifying Chinese herbal drugs on gene expression profile of bone marrow stromal cells from a rat model of corticosterone-induced osteoporosis]. ( Bian, Q; Huang, JH; Ning, Y; Shen, ZY; Wang, YJ; Yang, Z; Zhao, YJ, 2011) |
| " We measured food intake, body weight (including body fat weight) and plasma corticosterone levels in CRH-Tg and their wild-type littermates (WT) at 6 and 14 weeks old." | 3.77 | Corticotropin-releasing hormone (CRH) transgenic mice display hyperphagia with increased Agouti-related protein mRNA in the hypothalamic arcuate nucleus. ( Hashimoto, K; Iwasaki, Y; Makino, S; Nakayama, S; Nishiyama, M; Okada, Y; Okazaki, M; Shinahara, M; Stenzel-Poore, MP; Taguchi, T; Terada, Y; Tsuda, M; Tsugita, M, 2011) |
| " Basally, HRs display lower anxiety-like behavior compared to LRs along with higher neuropeptide Y (NPY) mRNA in the amygdala and the hippocampus." | 3.77 | Effects of a selective Y2R antagonist, JNJ-31020028, on nicotine abstinence-related social anxiety-like behavior, neuropeptide Y and corticotropin releasing factor mRNA levels in the novelty-seeking phenotype. ( Aydin, C; Isgor, C; Oztan, O, 2011) |
| " Food intake, anxiety-like behaviors, and serum levels of insulin, leptin, corticosterone, glucose and triglycerides were determined." | 3.77 | Effects of comfort food on food intake, anxiety-like behavior and the stress response in rats. ( Ferrari, EM; Melo, LL; Ortolani, D; Oyama, LM; Spadari-Bratfisch, RC, 2011) |
| "Sandhoff disease (SD) is a lysosomal disease caused by a mutation of the HEXB gene associated with excessive accumulation of GM2 ganglioside (GM2) in lysosomes and neurological manifestations." | 3.77 | Thymic involution and corticosterone level in Sandhoff disease model mice: new aspects the pathogenesis of GM2 gangliosidosis. ( Itoh, K; Matsuoka, K; Taki, T; Tsuji, D, 2011) |
| " In terms of anxiety-related behaviour and physiology, we found that prenatal poly I:C alone or in combination with juvenile stress had no effects on body weight, adrenal weight, and plasma concentration of corticosterone and cytokines in adult rats." | 3.77 | Differential effects of maternal immune activation and juvenile stress on anxiety-like behaviour and physiology in adult rats: no evidence for the "double-hit hypothesis". ( de Roo, CC; Fuchs, E; Ribic, A; Yee, N, 2011) |
| " Our study showed that stress reduced body weight, decreased sucrose intake and sucrose preference, and increased immobility in a forced swimming test." | 3.77 | Exposure to enriched environment restores the mRNA expression of mineralocorticoid and glucocorticoid receptors in the hippocampus and ameliorates depressive-like symptoms in chronically stressed rats. ( Liu, H; Sun, H; Yang, Y; Yao, Z; Zhang, J; Zhang, L, 2011) |
| " Experiment 2 showed that fluoxetine treatment administered via drinking water attenuated depressive-like behaviour in the FST and TST in individually housed female C57BL/6J mice, but had no effect on anxiety-like behaviour." | 3.76 | The lonely mouse: verification of a separation-induced model of depression in female mice. ( Brown, RE; Martin, AL, 2010) |
| " JNJ-31020028 was tested in vivo with microdialysis, in anxiety models, and on corticosterone release." | 3.76 | In vitro and in vivo characterization of JNJ-31020028 (N-(4-{4-[2-(diethylamino)-2-oxo-1-phenylethyl]piperazin-1-yl}-3-fluorophenyl)-2-pyridin-3-ylbenzamide), a selective brain penetrant small molecule antagonist of the neuropeptide Y Y(2) receptor. ( Aluisio, L; Atack, JR; Bonaventure, P; Carruthers, NI; Dvorak, C; Dvorak, L; Fraser, I; Galici, R; Lord, B; Lovenberg, TW; Morton, K; Motley, ST; Nepomuceno, D; Shoblock, JR; Sutton, SW; Swanson, DM; Welty, N, 2010) |
| "To investigate further whether low leptin levels alone were responsible for delayed puberty in colitis, we induced colitis in 23-day-old female mice using 3% dextran sodium sulfate (DSS), resulting in 10 days of worsening colitis." | 3.76 | Colitis causes delay in puberty in female mice out of proportion to changes in leptin and corticosterone. ( Cohn, S; DeBoer, MD; Li, Y, 2010) |
| " We found that high doses of CORT (100 microg/ml) result in rapid and dramatic increases in weight gain, increased adiposity, elevated plasma leptin, insulin and triglyceride levels, hyperphagia, and decreased home-cage locomotion." | 3.76 | Endocrine and physiological changes in response to chronic corticosterone: a potential model of the metabolic syndrome in mouse. ( Bhagat, SM; Bowles, NP; Karatsoreos, IN; McEwen, BS; Pfaff, DW; Weil, ZM, 2010) |
| " We characterized the pharmacokinetic/pharmacodynamic relationships of a prototypical ASI, (+)-(5R)-4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl]benzonitrile hydrochloride (CGS020286A, FAD286, FAD) and compared these profiles to those of the 11beta-hydroxylase inhibitor metyrapone (MET) in two rodent models of secondary hyperaldosteronism and corticosteronism." | 3.76 | Pharmacodynamic and pharmacokinetic characterization of the aldosterone synthase inhibitor FAD286 in two rodent models of hyperaldosteronism: comparison with the 11beta-hydroxylase inhibitor metyrapone. ( Beil, M; Fu, F; Hu, CW; Jeng, AY; Liang, G; Rigel, DF, 2010) |
| " Here, tonic-clonic seizures were induced with a convulsive dose of pentylenetetrazole (PTZ), and acute seizure recurrence was evoked with a subconvulsive dose of the drug." | 3.76 | Stress within the postseizure time window inhibits seizure recurrence. ( Cao, J; Duan, TT; Mao, RR; Tan, JW; Tian, M; Xu, L; Zhou, QX, 2010) |
| "Developmental deficits in GABAergic inhibition in the forebrain cause behavioral and endocrine abnormalities and selective antidepressant drug responsiveness indicative of anxious-depressive disorders such as melancholic depression, which are frequently characterized by HPA axis hyperactivity and greater efficacy of desipramine versus fluoxetine." | 3.76 | gamma-Aminobutyric acid-type A receptor deficits cause hypothalamic-pituitary-adrenal axis hyperactivity and antidepressant drug sensitivity reminiscent of melancholic forms of depression. ( Andrews, AM; Earnheart, JC; Lal, R; Luellen, BA; Luscher, B; Shen, Q, 2010) |
| "The results indicate that nicotine enhances susceptibility to periodontitis via nAChRs, which may act via suppressing protective immune responses through the cholinergic anti-inflammatory pathway." | 3.75 | Nicotinic acetylcholine receptor activation mediates nicotine-induced enhancement of experimental periodontitis. ( Breivik, T; Gjermo, P; Gundersen, Y; Opstad, PK; von Hörsten, S, 2009) |
| "This study shows that the BTBR T+tf/J mouse, a model for autism spectrum disorder (ASD), has increased levels of the stress hormone corticosterone, when compared to C57BL/6J mice." | 3.75 | Exaggerated responses to stress in the BTBR T+tf/J mouse: an unusual behavioral phenotype. ( Benno, R; Liggett, A; Schanz, N; Smirnova, Y; Vera, S, 2009) |
| "Thus, we examined the response to peripheral exenatide using telemetry in conscious, unrestrained rats under normotensive conditions and in a model of hypertension/metabolic syndrome induced by corticosterone." | 3.75 | Exenatide improves hypertension in a rat model of the metabolic syndrome. ( Guss, S; Landry, J; Laugero, KD; Parkes, DG; Stonehouse, AH; Vu, C, 2009) |
| " IBU blocked LPS-induced fever but did not block LPS-induced increases in plasma cytokines and corticosterone in the pregnant dam." | 3.75 | Effects of prenatal immune activation on hippocampal neurogenesis in the rat. ( Ashdown, H; Boksa, P; Cui, K; Luheshi, GN, 2009) |
| " Here we describe a mouse model of an anxiety/depressive-like state induced by chronic corticosterone treatment." | 3.75 | Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression. ( Antonijevic, IA; Artymyshyn, RP; Craig, DA; David, DJ; Drew, M; Gardier, AM; Gerald, C; Guiard, BP; Guilloux, JP; Hen, R; Leonardo, ED; Marsteller, D; Mendez, I; Rainer, Q; Samuels, BA; Wang, JW, 2009) |
| " Green odor had inhibitory effects on the stress-induced corticosterone response, body-weight loss, and adrenal hypertrophy." | 3.75 | "Green odor" inhalation by rats down-regulates stress-induced increases in Fos expression in stress-related forebrain regions. ( Fukada, M; Ito, A; Komaki, R; Miyoshi, M; Ueki, S; Watanabe, T, 2009) |
| " Oral systemic effects of MF were inversely lower than that of BDP on thymolysis, plasma corticosterone lowering, and suppression of body weight gain in mice." | 3.75 | Dissociation of local anti-inflammatory effect and systemic effects of mometasone furoate in mice. ( Kamei, C; Ogawa, M; Sakonjo, H, 2009) |
| " By acoustic and restraint stress-induced alterations such as high corticosterone levels, an anti-inflammatory immune conditioning with an ex vivo hyperinducibility of interleukin-10 of splenocytes and a massive loss of body weight were significantly reduced in the maternally separated group compared with conventionally bred control mice." | 3.75 | Mild postnatal separation stress reduces repeated stress-induced immunosuppression in adult BALB/c mice. ( Kiank, C; Mundt, A; Schuett, C, 2009) |
| " Circulating LH, follicle-stimulating hormone and corticosterone in neonates, and testosterone at adulthood were unaffected by birth hypoxia." | 3.74 | Global birth hypoxia increases the neonatal testosterone surge in the rat. ( Boksa, P; Zhang, Y, 2008) |
| " Using a non-immunogenic syngeneic mammary adenocarcinoma line (MADB106) we studied: (a) NK cytotoxicity (NKC) in marginating-pulmonary (MP) and in circulating leukocytes; (b) resistance to experimental lung metastasis; and (c) in vitro susceptibility of NKC to corticosterone and prostaglandin-E(2), substances thought to mediate postoperative immunosuppression." | 3.74 | Amelioration of operation-induced suppression of marginating pulmonary NK activity using poly IC: a potential approach to reduce postoperative metastasis. ( Abudarham, N; Ben-Eliyahu, S; Melamed, R; Rosenne, E; Schwartz, Y; Shakhar, G, 2007) |
| "In controls, chronic mild stress resulted in symptoms of chronic stress state characterized by typical somatic (body weight reduction, thymus involution) and endocrine changes (resting plasma ACTH and corticosterone elevation and POMC mRNA elevation in anterior lobe of the pituitary)." | 3.74 | The role of vasopressin in chronic stress studied in a chronic mild stress model of depression. ( Bagdy, G; Barna, I; Csabail, K; Domokos, A; Makara, GB; Zelena, D, 2007) |
| "The data demonstrate that EA activates the adrenals to increase plasma corticosterone levels and suppress edema and suggest that EA effects differ in healthy subjects and in those with pathologies." | 3.74 | Corticosterone mediates electroacupuncture-produced anti-edema in a rat model of inflammation. ( Berman, BM; Lao, L; Li, A; Ren, K; Tan, M; Wang, Y; Zhang, H; Zhang, RX, 2007) |
| " We have studied the effect of (+)-catechin on a gastric ulcer model involving damage to gastric injury by ischaemia- reperfusion (I/R) in rats." | 3.74 | Protective effect of (+)-catechin against gastric mucosal injury induced by ischaemia-reperfusion in rats. ( Rao, ChV; Vijayakumar, M, 2007) |
| "Cholecystokinin (CCK) involvement in depression-like disorders is poorly documented." | 3.74 | Repeated social defeat-induced depression-like behavioral and biological alterations in rats: involvement of cholecystokinin. ( Becker, C; Benoliel, JJ; Blugeot, A; Hamon, M; Rivat, C; Zeau, B, 2008) |
| " Here, we investigated both the immediate and enduring impact of SS in adolescence on anxiety-like behaviour in the elevated plus maze (EPM) and determined the temporal pattern of corticosterone release after confinement to the open arm of the EPM." | 3.74 | Effects of chronic social stress in adolescence on anxiety and neuroendocrine response to mild stress in male and female rats. ( Mathews, IZ; McCormick, CM; Smith, C, 2008) |
| " We hypothesized that chrysin decreases anxiety via interaction with the GABA(A) receptor in laboratory rats as measured by elevated plus-maze (EPM), corticosterone, and catecholamine assays." | 3.74 | Evaluation of the anxiolytic effects of chrysin, a Passiflora incarnata extract, in the laboratory rat. ( Brown, E'; Ceremuga, TE; Hurd, NS; McCall, S, 2007) |
| "This study demonstrates the changes in six different pathophysiological parameters such as body weight, body temperature, fecal pellet count, blood-brain barrier (BBB) permeability, plasma corticosterone level and emergence of hemorrhagic peptic ulcer spots due to exposure to high environmental heat in three different age groups of freely moving rats." | 3.74 | Study of changes in some pathophysiological stress markers in different age groups of an animal model of acute and chronic heat stress. ( Sinha, RK, 2007) |
| "A rat model of depression has been recently developed by exogenous corticosterone administration." | 3.74 | A mouse model of depression induced by repeated corticosterone injections. ( Du, L; Ma, R; Shen, J; Su, H; Xing, D; Zhao, Y, 2008) |
| " Effects on disease progression were measured by paw swelling, bone mineral density (BMD), body weights, plasma corticosterone (CST), and tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta, IL-6, and glucocorticoid receptor (GR) mRNA expression in paw tissue." | 3.74 | Modeling corticosteroid effects in a rat model of rheumatoid arthritis II: mechanistic pharmacodynamic model for dexamethasone effects in Lewis rats with collagen-induced arthritis. ( Almon, RR; Dubois, DC; Earp, JC; Jusko, WJ; Molano, DS; Pyszczynski, NA, 2008) |
| " Disease progression was monitored by paw swelling, bone mineral density (BMD), body weights, plasma corticosterone (CST) concentrations, and tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta, IL-6, and glucocorticoid receptor (GR) mRNA expression in paw tissue." | 3.74 | Modeling corticosteroid effects in a rat model of rheumatoid arthritis I: mechanistic disease progression model for the time course of collagen-induced arthritis in Lewis rats. ( Almon, RR; Dubois, DC; Earp, JC; Jusko, WJ; Keller, CE; Molano, DS; Pyszczynski, NA, 2008) |
| " The purpose of the present study was to characterize the effect of repeated corticosterone (CORT) injections and repeated restraint stress on anxiety and depression-like behavior in male rats." | 3.73 | Effect of repeated corticosterone injections and restraint stress on anxiety and depression-like behavior in male rats. ( Davis, AC; Gregus, A; Kalynchuk, LE; Wintink, AJ, 2005) |
| "C57BL/6 mice were either fed ad libitum or fasted for 48 h and given an intraperitoneal injection of saline or recombinant leptin (1 microg/g of body weight) twice daily for 48 h before bacterial challenge." | 3.73 | Leptin corrects host defense defects after acute starvation in murine pneumococcal pneumonia. ( Huffnagle, GB; Mancuso, P; Olszewski, MA; Peters-Golden, M; Phipps, J, 2006) |
| " We studied mice bearing a truncated Mecp2 allele (Mecp2(308/Y) mice) and found evidence of increased anxiety-like behavior and an abnormal stress response as evidenced by elevated serum corticosterone levels." | 3.73 | Enhanced anxiety and stress-induced corticosterone release are associated with increased Crh expression in a mouse model of Rett syndrome. ( Bundle, SF; Carson, JP; McGill, BE; Thaller, C; Yaylaoglu, MB; Zoghbi, HY, 2006) |
| "High doses of diazepam (10-20 mg/kg) were shown to reduce the volume of acute carrageenan-induced inflammatory paw edema in rats." | 3.72 | Reduction of inflammation in rats by diazepam: tolerance development. ( de Nucci, G; Lazzarini, R; Malucelli, BE; Muscará, MN; Palermo-Neto, J, 2003) |
| "Topiramate is currently used in the treatment of epilepsy, but this anticonvulsant drug has also been reported to exert mood-stabilizing effects and induce weight loss in patients." | 3.72 | Topiramate normalizes hippocampal NPY-LI in flinders sensitive line 'depressed' rats and upregulates NPY, galanin, and CRH-LI in the hypothalamus: implications for mood-stabilizing and weight loss-inducing effects. ( Bolwig, G; Husum, H; Mathé, A; Termeer, E; Van Kammen, D, 2003) |
| "Chronic hypoxia in our neonatal rat model was associated with decrease in growth hormone levels and an increase in corticosterone levels." | 3.72 | Endocrine changes in a rat model of chronic hypoxia mimicking cyanotic heart disease. ( Azar, N; Azar, ST; Bitar, FF; Dbaibo, GS; Mroueh, S; Nasser, M; Obeid, M; Zayour, D, 2003) |
| "The humoral response and the role of catecholamines and corticosterone were analyzed in a chronic mild stress (CMS) model of depression." | 3.72 | Impaired T-cell dependent humoral response and its relationship with T lymphocyte sensitivity to stress hormones in a chronic mild stress model of depression. ( Ayelli-Edgar, V; Genaro, AM; Silberman, DM; Zieher, LM; Zorrilla-Zubilete, M, 2004) |
| " We then measured the corticosterone and fever responses to LPS stimulation during the withdrawal period." | 3.72 | Suppressed fever and hypersensitivity responses in chicks prenatally exposed to opiates. ( Schrott, LM; Sparber, SB, 2004) |
| " During early infection, stressed mice displayed decreased body weights and spontaneous activity; while increased behavioral signs of illness and plasma corticosterone (CORT) levels." | 3.72 | Chronic restraint stress during early Theiler's virus infection exacerbates the subsequent demyelinating disease in SJL mice. ( Meagher, MW; Sieve, AN; Steelman, AJ; Storts, R; Welsh, CJ; Welsh, TH; Young, CR, 2004) |
| " Following discrete paraventricular nucleus (PVN) lesions plasma corticosterone was increased 14 days after adjuvant injection as in controls, when hind paw inflammation was apparent." | 3.71 | The effect of hypothalamic lesions on hypothalamo-pituitary-adrenal axis activity and inflammation in adjuvant-induced arthritis. ( Coventry, TL; Harbuz, MS; Jessop, DS; Lightman, SL; Makara, GB; Zelena, D, 2001) |
| " These long-term neuroendocrinological effects are mediated, at least in part, by stress-induced maternal corticosterone increase during pregnancy and stress-induced maternal anxiety during the postnatal period." | 3.71 | Hormonal and behavioural abnormalities induced by stress in utero: an animal model for depression. ( Darnaudery, M; Maccari, S; Van Reeth, O, 2001) |
| " Stress-related stimulation of the hypothalamic-pituitary-adrenal axis produced a rise in circulating corticosterone levels that correlated significantly with the impairment of some immunological parameters, such as delayed hypersensitivity reactions to dinitrofluorobenzene and to sheep red blood cells, together with changes in splenocyte proliferation and phagocytic activity of peritoneal macrophages." | 3.71 | An experimental model of stress-induced immunosuppression produced by electrical stimulation of the brain in the rat. ( Lozoya, X; Puebla-Pérez, AM; Villaseñor-García, MM, 2001) |
| ", a late stage of sepsis) or sham operation to measure plasma levels of corticosterone and corticotropin as well as adrenal contents of corticosterone." | 3.71 | Adrenal insufficiency during the late stage of polymicrobial sepsis. ( Chaudry, IH; Jackman, D; Koo, DJ; Wang, P, 2001) |
| " Given the importance of neurodevelopmental factors in the pathophysiology of schizophrenia, the present experiments investigated the effects of restraint, exposure to inescapable footshock and corticosterone administration during the last trimester of pregnancy, on the development of LI in the adult male and female offspring." | 3.71 | Gender-dependent differences in latent inhibition following prenatal stress and corticosterone administration. ( Shalev, U; Weiner, I, 2001) |
| "The purpose of the present study was to determine whether exposure to stress or elevated corticosterone concentrations in the days preceding cerebral ischemia exacerbates ischemic injury as assessed by histological and behavioral outcomes." | 3.71 | Social stress exacerbates focal cerebral ischemia in mice. ( DeVries, AC; Hattori, K; Hurn, PD; Morahan, MB; Sugo, N; Traystman, RJ, 2002) |
| "The present data indicate that testosterone plays a role in the development of obesity and NIDDM in young OLETF rats, but that changes of leptin production in white adipose tissue may not be important in the development of obesity in young OLETF rats." | 3.70 | Orchiectomy and response to testosterone in the development of obesity in young Otsuka-Long-Evans-Tokushima Fatty (OLETF) rats. ( Abe, Y; Ibuki, Y; Mori, M; Ohtani, KI; Sato, N; Shimizu, H; Takahashi, H; Tsuchiya, T; Uehara, Y, 1998) |
| "Previous studies on human breast cancer patients showed a decline in circulating melatonin levels corresponding to primary tumor growth and an increase when relapse occurred." | 3.70 | Serial transplants of DMBA-induced mammary tumors in Fischer rats as a model system for human breast cancer. VI. The role of different forms of tumor-associated stress for the regulation of pineal melatonin secretion. ( Bartsch, C; Bartsch, H; Besenthal, I; Buchberger, A; Effenberger-Klein, A; Kruse-Jarres, JD; Mecke, D; Rokos, H; Stieglitz, A, 1999) |
| " To identify signals that activate this system, we studied acutely diabetic rats that had metabolic acidosis and increased corticosterone production." | 3.70 | Evaluation of signals activating ubiquitin-proteasome proteolysis in a model of muscle wasting. ( Bailey, JL; Jurkovitz, C; Mitch, WE; Newby, D; Price, SR; Wang, X, 1999) |
| "Cerulein-induced pancreatitis or closed duodenal loop pancreatitis was produced in rats that had undergone adrenalectomy or sham adrenalectomy, and the serum corticosterone and interleukin 8 levels and the intensity of the pancreatitis were examined." | 3.69 | The role of endogenous glucocorticoids in rat experimental models of acute pancreatitis. ( Abe, R; Abe, T; Kashimura, J; Kimura, K; Koizumi, M; Shimosegawa, T; Toyota, T, 1995) |
| " The dose-dependent effects of naloxone on PCS and body weight were studied in male Sprague-Dawley rats rendered physically dependent on morphine by injecting increasing doses of 40-120 mg/kg/day, s." | 3.69 | Quantitative properties of plasma corticosterone elevation induced by naloxone-precipitated withdrawal in morphine-dependent rats. ( Fukunaga, Y; Kishioka, S; Nishida, S; Yamamoto, H, 1994) |
| "It was established that the acute aseptic inflammation was accompanied by stress reaction development which appeared as characteristic changes of blood eosinophils, corticosterone and insulin concentrations." | 3.68 | [The interrelationship between inflammation and the stress reaction]. ( Kuz'menko, VV; Malyshev, VV; Vasil'eva, LS, 1993) |
| "The content of corticosterone in the rabbits blood plasma in dynamics of experimental brain concussion was studied." | 3.68 | [Plasma corticosterone level in experimental mild cranio-cerebral injury in rabbits]. ( Kop'ev, OV; Minchenko, AG; Vasil'eva, IG, 1991) |
| "30% of patients with essential hypertension have a decreased adrenal response to angiotensin II (A II) on a low but not a high sodium intake." | 3.66 | Decreased adrenal responsiveness to angiotensin II: a defect present in spontaneously hypertensive rats. A possible model of human essential hypertension. ( Braley, LM; Menachery, A; Williams, GH, 1982) |
| "Chronic hypertension has been produced in mongrel dogs by the long-term oral administration of metyrapone (100 mg/kg per day)." | 3.65 | Multifactorial analysis of chronic hypertension induced by electrolyte-active steroids in trained, unanesthetized dogs. ( Bravo, EL; Dustan, HP; Tarazi, RC, 1977) |
| "Treatment with paroxetine was performed per os with a dosage of 20 mg/g BW." | 2.78 | Chronic social stress during adolescence: interplay of paroxetine treatment and ageing. ( Liebl, C; Müller, MB; Scharf, SH; Schmidt, MV; Sterlemann, V, 2013) |
| "Olanzapine treatment reduced development of ABA in rats by reducing running wheel activity, starvation-induced hypothermia and activation of the hypothalamus-pituitary-adrenal axis." | 2.71 | Olanzapine reduces physical activity in rats exposed to activity-based anorexia: possible implications for treatment of anorexia nervosa? ( Adan, RA; Hillebrand, JJ; Kas, MJ; van Elburg, AA; van Engeland, H, 2005) |
| "Mycophenolic acid was detected in all cats." | 2.61 | ( Abrams, G; Adolfsson, E; Agarwal, PK; Akkan, AG; Al Alhareth, NS; Alves, VGL; Armentano, R; Bahroos, E; Baig, M; Baldridge, KK; Barman, S; Bartolucci, C; Basit, A; Bertoli, SV; Bian, L; Bigatti, G; Bobenko, AI; Boix, PP; Bokulic, T; Bolink, HJ; Borowiec, J; Bulski, W; Burciaga, J; Butt, NS; Cai, AL; Campos, AM; Cao, G; Cao, Y; Čapo, I; Caruso, ML; Chao, CT; Cheatum, CM; Chelminski, K; Chen, AJW; Chen, C; Chen, CH; Chen, D; Chen, G; Chen, H; Chen, LH; Chen, R; Chen, RX; Chen, X; Cherdtrakulkiat, R; Chirvony, VS; Cho, JG; Chu, K; Ciurlino, D; Coletta, S; Contaldo, G; Crispi, F; Cui, JF; D'Esposito, M; de Biase, S; Demir, B; Deng, W; Deng, Z; Di Pinto, F; Domenech-Ximenos, B; Dong, G; Drácz, L; Du, XJ; Duan, LJ; Duan, Y; Ekendahl, D; Fan, W; Fang, L; Feng, C; Followill, DS; Foreman, SC; Fortunato, G; Frew, R; Fu, M; Gaál, V; Ganzevoort, W; Gao, DM; Gao, X; Gao, ZW; Garcia-Alvarez, A; Garza, MS; Gauthier, L; Gazzaz, ZJ; Ge, RS; Geng, Y; Genovesi, S; Geoffroy, V; Georg, D; Gigli, GL; Gong, J; Gong, Q; Groeneveld, J; Guerra, V; Guo, Q; Guo, X; Güttinger, R; Guyo, U; Haldar, J; Han, DS; Han, S; Hao, W; Hayman, A; He, D; Heidari, A; Heller, S; Ho, CT; Ho, SL; Hong, SN; Hou, YJ; Hu, D; Hu, X; Hu, ZY; Huang, JW; Huang, KC; Huang, Q; Huang, T; Hwang, JK; Izewska, J; Jablonski, CL; Jameel, T; Jeong, HK; Ji, J; Jia, Z; Jiang, W; Jiang, Y; Kalumpha, M; Kang, JH; Kazantsev, P; Kazemier, BM; Kebede, B; Khan, SA; Kiss, J; Kohen, A; Kolbenheyer, E; Konai, MM; Koniarova, I; Kornblith, E; Krawetz, RJ; Kreouzis, T; Kry, SF; Laepple, T; Lalošević, D; Lan, Y; Lawung, R; Lechner, W; Lee, KH; Lee, YH; Leonard, C; Li, C; Li, CF; Li, CM; Li, F; Li, J; Li, L; Li, S; Li, X; Li, Y; Li, YB; Li, Z; Liang, C; Lin, J; Lin, XH; Ling, M; Link, TM; Liu, HH; Liu, J; Liu, M; Liu, W; Liu, YP; Lou, H; Lu, G; Lu, M; Lun, SM; Ma, Z; Mackensen, A; Majumdar, S; Martineau, C; Martínez-Pastor, JP; McQuaid, JR; Mehrabian, H; Meng, Y; Miao, T; Miljković, D; Mo, J; Mohamed, HSH; Mohtadi, M; Mol, BWJ; Moosavi, L; Mosdósi, B; Nabu, S; Nava, E; Ni, L; Novakovic-Agopian, T; Nyamunda, BC; Nyul, Z; Önal, B; Özen, D; Özyazgan, S; Pajkrt, E; Palazon, F; Park, HW; Patai, Á; Patai, ÁV; Patzke, GR; Payette, G; Pedoia, V; Peelen, MJCS; Pellitteri, G; Peng, J; Perea, RJ; Pérez-Del-Rey, D; Popović, DJ; Popović, JK; Popović, KJ; Posecion, L; Povall, J; Prachayasittikul, S; Prachayasittikul, V; Prat-González, S; Qi, B; Qu, B; Rakshit, S; Ravelli, ACJ; Ren, ZG; Rivera, SM; Salo, P; Samaddar, S; Samper, JLA; Samy El Gendy, NM; Schmitt, N; Sekerbayev, KS; Sepúlveda-Martínez, Á; Sessolo, M; Severi, S; Sha, Y; Shen, FF; Shen, X; Shen, Y; Singh, P; Sinthupoom, N; Siri, S; Sitges, M; Slovak, JE; Solymosi, N; Song, H; Song, J; Song, M; Spingler, B; Stewart, I; Su, BL; Su, JF; Suming, L; Sun, JX; Tantimavanich, S; Tashkandi, JM; Taurbayev, TI; Tedgren, AC; Tenhunen, M; Thwaites, DI; Tibrewala, R; Tomsejm, M; Triana, CA; Vakira, FM; Valdez, M; Valente, M; Valentini, AM; Van de Winckel, A; van der Lee, R; Varga, F; Varga, M; Villarino, NF; Villemur, R; Vinatha, SP; Vincenti, A; Voskamp, BJ; Wang, B; Wang, C; Wang, H; Wang, HT; Wang, J; Wang, M; Wang, N; Wang, NC; Wang, Q; Wang, S; Wang, X; Wang, Y; Wang, Z; Wen, N; Wesolowska, P; Willis, M; Wu, C; Wu, D; Wu, L; Wu, X; Wu, Z; Xia, JM; Xia, X; Xia, Y; Xiao, J; Xiao, Y; Xie, CL; Xie, LM; Xie, S; Xing, Z; Xu, C; Xu, J; Yan, D; Yan, K; Yang, S; Yang, X; Yang, XW; Ye, M; Yin, Z; Yoon, N; Yoon, Y; Yu, H; Yu, K; Yu, ZY; Zhang, B; Zhang, GY; Zhang, H; Zhang, J; Zhang, M; Zhang, Q; Zhang, S; Zhang, W; Zhang, X; Zhang, Y; Zhang, YW; Zhang, Z; Zhao, D; Zhao, F; Zhao, P; Zhao, W; Zhao, Z; Zheng, C; Zhi, D; Zhou, C; Zhou, FY; Zhu, D; Zhu, J; Zhu, Q; Zinyama, NP; Zou, M; Zou, Z, 2019) |
| "Animal models of PTSD offer the opportunity to distinguish between biological and socio-cultural factors, which so often enter the discussion about gender differences in PTSD prevalence." | 2.47 | Gender differences in animal models of posttraumatic stress disorder. ( Cohen, H; Yehuda, R, 2011) |
| "Postpartum depression is a mentally disabling disease with multifactorial etiology that affects women worldwide." | 1.91 | Postpartum depression in rats causes poor maternal care and neurochemical alterations on dams and long-lasting impairment in sociability on the offspring. ( Abreu, GR; Bianco, AC; Bocco, BMLC; de Lima, MA; Flório, JC; Fonseca, TL; Fukushima, AR; Lebrun, I; Manes, M; Miglioli, J; Munhoz, C; Pantaleon, LP; Ribeiro, BB; Ricci, EL; Spinosa, HS; Waziry, PAF; Zaccarelli-Magalhães, J, 2023) |
| "BDNF-HA2TAT/AAV therapeutically effects PTSD caused by SPS, with changes seen in plasma corticosterone and BDNF-TrkB pathways within the hippocampus; therefore, BDNF-HA2TAT/AAV may be a promising treatment for patients with PTSD." | 1.91 | Brain-Derived Neurotrophic Factor Delivered Intranasally Relieves Post-Traumatic Stress Disorder Symptoms Caused by a Single Prolonged Stress in Rats. ( Dang, Y; Deng, L; Ma, C; Zhang, H; Zhang, L, 2023) |
| "Treatment with fasudil and sertraline significantly restored the behavioral changes and normalized the corticosterone levels." | 1.91 | Investigations on Rho/ROCK signaling in post-traumatic stress disorder-like behavior in mice. ( Bali, A; Hanifa, M; Sree, AB, 2023) |
| "Posttraumatic stress disorder (PTSD) is a serious neuropsychiatric disorder that occurs after exposure to stressful, fearful, or troubling events." | 1.91 | Synergistic effects of combined therapy with cerebrolysin and enriched environment on anxiety-like behavior and spatial cognitive deficits in posttraumatic stress disorder-like mouse model. ( Farajdokht, F; Hosseini, L; Hosseini, MJ; Mahmoudi, J; Pasokh, A; Sadigh-Eteghad, S; Salehi-Pourmehr, H; Sandoghchian Shotorbani, S; Ziaee, M, 2023) |
| "Depression is one of the most common mood disturbances worldwide." | 1.91 | SNS alleviates depression-like behaviors in CUMS mice by regluating dendritic spines via NCOA4-mediated ferritinophagy. ( Ao, HQ; Chen, WC; Chen, WG; He, CY; He, SQ; Li, T; Lin, HS; Liu, Y; Song, ML; Sun, HT; Yang, XM; Zhang, MJ; Zhang, Y; Zhong, XD, 2023) |
| "Quercetin is a flavonoid compound, which has anti-inflammatory and antioxidant roles." | 1.91 | Quercetin mitigates depression-like behavior via the suppression of neuroinflammation and oxidative damage in corticosterone-induced mice. ( Ge, C; Lei, L; Wang, S; Wu, X, 2023) |
| "Depression is a common psychiatric disorder affecting around 300 million people worldwide." | 1.91 | Emotional behaviors as well as the hippocampal reelin expression in C57BL/6N male mice chronically treated with corticosterone. ( Hiramatsu, M; Ibi, D; Kinoshita, M; Nakasai, G; Sawahata, M; Takaba, R; Yamada, K, 2023) |
| "Anxious depression is a prevalent disease with devastating consequences." | 1.91 | Social avoidance and altered hypothalamic-pituitary-adrenal axis in a mouse model of anxious depression: The role of LPA ( Estivill-Torrús, G; Gómez-Salas, FJ; Moreno-Fernández, RD; Nieto-Quero, A; Pedraza, C; Rodríguez de Fonseca, F; Sampedro-Piquero, P; Santín, LJ, 2023) |
| "Most notably, chronic hypercortisolism caused a persistent circadian rhythm disruption in VAT through core clock genes modulation." | 1.72 | Glucocorticoid-induced Fingerprints on Visceral Adipose Tissue Transcriptome and Epigenome. ( Boswell, L; Carmona, F; Casals, G; Di Croce, L; Enseñat, J; García-Eguren, G; Giró, O; González-Ramírez, M; Gracia, M; Halperin, I; Hanzu, FA; Mora, M; Squarcia, M; Vega-Beyhart, A; Vidal, O; Vizán, P, 2022) |
| "Twenty days after ovariectomy, PTSD was induced by single prolonged stress (SPS) model." | 1.72 | Effect of treadmill exercise on serum corticosterone, serum and hippocampal BDNF, hippocampal apoptosis and anxiety behavior in an ovariectomized rat model of post-traumatic stress disorder (PTSD). ( Akhoundzadeh, K; Roshani, F; Shafia, S; Yakhkeshi, R, 2022) |
| " Experimentally, the chronic administration of corticosterone (CORT) in rodents has been reported to promote depressive-like behaviors." | 1.72 | Protective effect of Myrcia pubipetala Miq. against the alterations in oxidative stress parameters in an animal model of depression induced by corticosterone. ( Alberton, MD; Barauna, SC; de Lima, DD; Lopes, BG; Magro, DDD; Rocha, FE; Shuster, AL; Wayszceyk, S, 2022) |
| "Treatment of sleep disorders promotes the long-term use of commercially available sleep inducers that have several adverse effects, including addiction, systemic fatigue, weakness, loss of concentration, headache, and digestive problems." | 1.72 | Effect of Hibiscus syriacus Linnaeus extract and its active constituent, saponarin, in animal models of stress-induced sleep disturbances and pentobarbital-induced sleep. ( Kim, YR; Lee, MY; Lee, SM; Lee, SY; Shim, I, 2022) |
| "Buprenorphine treatment reduced facial pain expression scores, improved mobility, stance and lameness scores and it did not supress the CFA-induced ankle swelling, contrary to carprofen." | 1.72 | Effects of buprenorphine on model development in an adjuvant-induced monoarthritis rat model. ( Abelson, KSP; Berke, MS; Fensholdt, LKD; Hestehave, S; Kalliokoski, O, 2022) |
| "Major depression is a leading contributor to the global burden of disease." | 1.72 | Lower antidepressant response to fluoxetine is associated with anxiety-like behavior, hippocampal oxidative imbalance, and increase on peripheral IL-17 and IFN-γ levels. ( Becker, G; Bochi, GV; Camargo, LFM; da Silva Carlotto, M; Dos Santos, BM; Fialho, MFP; Oliveira, SM; Pereira, GC; Pillat, MM; Piton, E; Ramanzini, LG; Trevisan, G; Zanchet, EM, 2022) |
| "Posttraumatic stress disorder (PTSD) is an anxiety disorder that occurs following exposure to somatic or psychotic trauma." | 1.72 | Prior short-term exercise prevents behavioral and biochemical abnormalities induced by single prolonged stress in a rat model of posttraumatic stress disorder. ( Afsari, R; Dehkordi, NS; Mirjalili, R; Rashidy-Pour, A; Shafia, S; Shokouh, E, 2022) |
| "Intestinal dysbacteriosis is associated with depression." | 1.72 | Antibiotics-induced depression in mice via the microbiota-gut-brain axis. ( Deng, H; Fan, X; Ji, H; Qiu, J; Shen, X, 2022) |
| "Depression is positively correlated with the high incidence and low survival rate of cancers, while more cancer patients suffer depression." | 1.72 | The combination of chronic stress and smoke exacerbated depression-like changes and lung cancer factor expression in A/J mice: Involve inflammation and BDNF dysfunction. ( Li, KW; Liu, BP; Song, C; Zhang, C; Zhang, YP, 2022) |
| "Thus, resilience or susceptibility to PTSD was consistent with changes in glucocorticoid metabolism." | 1.72 | Mechanisms of Susceptibility and Resilience to PTSD: Role of Dopamine Metabolism and BDNF Expression in the Hippocampus. ( Downey, HF; Fedotova, JO; Ivleva, IS; Karpenko, MN; Kondashevskaya, MV; Manukhina, EB; Pashkov, AA; Shatilov, VA; Tseilikman, OB; Tseilikman, VE; Zhukov, MS, 2022) |
| "Depression is a very common mental disorder and mechanism that is associated with mitochondrial dysfunction." | 1.72 | Antidepressant-Like Effects of Edaravone and Minocycline: Investigation of Oxidative Stress, Neuroinflammation, Neurotrophic, and Apoptotic Pathways. ( Bagheri, A; Motafeghi, F; Seyedabadi, M; Shaki, F; Shokrzadeh, M, 2022) |
| "Depression is a psychiatric disorder leading to anhedonia and lack of interest and motivation." | 1.72 | Antidepressive-Like Effect of ( Alhalmi, A; Kumar, G; Pathak, D; Sharma, A; Singh, T; Virmani, T, 2022) |
| "Depression is a common, chronic, and often recurrent serious mood disorder." | 1.72 | Neuroprotective and Antioxidant Effects of Riparin I in a Model of Depression Induced by Corticosterone in Female Mice. ( Adelvane de Paula Rodrigues, F; Barbosa-Filho, JM; Cavalcanti Capibaribe, VC; Chavez Gutierrez, SJ; de Castro Chaves, R; Ferreira de Oliveira, N; Florenço de Sousa, FC; Lopes Sales, IS; Maia Oliveira, IC; Maria de França Fonteles, M; Rodrigues de Carvalho, AM; Rodrigues, GC; Teodorio Vidal, LM; Vasconcelos Mallmann, AS, 2022) |
| "Propranolol treatment abrogated the elaboration of inflammatory cytokine mRNA expression in the brain instigated in our model, having no treatment effects in non-DFP exposed groups." | 1.62 | The β-adrenergic receptor blocker and anti-inflammatory drug propranolol mitigates brain cytokine expression in a long-term model of Gulf War Illness. ( Kelly, KA; Michalovicz, LT; Miller, DB; O'Callaghan, JP; Sullivan, K, 2021) |
| "Rats with recurrent depression are highly susceptible to stress and exhibit depression-like behaviours such as weight loss, increased immobility time in tail suspension test, and reduced sucrose preference index." | 1.62 | Behavioral and Neurochemical Changes in Rats with Recurrent Depression induced by chronic unpredictable stress. ( Chen, L; Hong, C; Huang, Z; Kong, W; Qiu, F; Wang, L; Zhang, D; Zhang, G; Zhao, J; Zhong, X, 2021) |
| "Corticosterone accumulation was detected in the frontal cortex (FC) and the hippocampus of the MCAO-KM group." | 1.62 | A Comparative Study of Koizumi and Longa Methods of Intraluminal Filament Middle Cerebral Artery Occlusion in Rats: Early Corticosterone and Inflammatory Response in the Hippocampus and Frontal Cortex. ( Gulyaeva, NV; Lazareva, NA; Moiseeva, YV; Onufriev, MV; Zhanina, MY, 2021) |
| "Post-traumatic stress disorder (PTSD) is a mental disorder that is linked with the onset of multiple anxiety-like behaviors." | 1.62 | The effects of laser stimulation at acupoint ST36 on anxiety-like behaviors and anterior cingulate cortex c-Fos expression in a rat post-traumatic stress disorder model. ( Liu, H; Liu, L; Liu, S; Qu, X; Shen, X; Yang, Y, 2021) |
| "Post-traumatic stress disorder (PTSD) is a psychological disorder affecting many around the world." | 1.62 | Non-selective orexin-receptor antagonist attenuates stress-re-stress-induced core PTSD-like symptoms in rats: Behavioural and neurochemical analyses. ( Krishnamurthy, S; Prajapati, SK, 2021) |
| "Interestingly, male rats in the MS3h-PTSD group showed decreased anxiety, but no similar changes were found in female rats, suggesting a degree of gender specificity in coping with stress after mild MS." | 1.62 | Maternal Separation-Induced Histone Acetylation Correlates with BDNF-Programmed Synaptic Changes in an Animal Model of PTSD with Sex Differences. ( Gou, L; Jiang, L; Kong, Y; Li, Q; Lian, B; Sun, H; Sun, L; Wang, Y; Zhang, X, 2021) |
| "Major depressive disorder is a common debilitating mental health problem that represents one of the leading causes of disability." | 1.62 | Adult neurogenesis augmentation attenuates anhedonia and HPA axis dysregulation in a mouse model of chronic stress and depression. ( Belzung, C; Brizard, B; Eliwa, H; Hen, R; Le Guisquet, AM; Surget, A, 2021) |
| "Depression is a pervasive or persistent mental disorder that causes mood, cognitive and memory deficits." | 1.62 | Uncaria rhynchophylla ameliorates unpredictable chronic mild stress-induced depression in mice via activating 5-HT ( Dai, SF; Deng, XP; Huang, HL; Li, S; Liang, JH; Liu, CQ; Luan, ZL; Ma, XC; Qiao, YL; Sun, CP; Yu, ZL; Zhang, ZJ; Zhou, JJ, 2021) |
| "The primary motor symptoms of Parkinson's disease (PD) result from the degeneration of dopamine-producing neurons of the substantia nigra pars compacta (SNc), and often, the loss is asymmetrical, resulting in unilateral tremor presentation." | 1.62 | Characterizing the protracted neurobiological and neuroanatomical effects of paraquat in a murine model of Parkinson's disease. ( Ayoub, K; Beauchamp, S; Derksen, A; Dwyer, Z; Farmer, K; Fortin, T; Hayley, S; Rudyk, C; Shail, P; Torres, C; Ventura, K, 2021) |
| "Another pandemic disease is type II diabetes mellitus (T2D) that is estimated to affect half a billion people in the world." | 1.62 | 16α-Bromoepiandrosterone as a new candidate for experimental diabetes-tuberculosis co-morbidity treatment. ( Baay-Guzman, G; Barrios-Payan, JA; Bini, E; Carranza, A; Chamberlin, W; Ge, Y; Hernández-Pando, R; López-Torres, MO; Marquina-Castillo, B; Mata-Espinosa, D; Ramos-Espinosa, O; Torre-Villalvazo, I; Torres, N; Tovar, A; Yepez, SH, 2021) |
| "Rats that exhibited PTSD-phenotype were characterized by blunted basal corticosterone pulsatility amplitude and a blunted corticosterone response to a stressor." | 1.62 | Is PTSD-Phenotype Associated with HPA-Axis Sensitivity? Feedback Inhibition and Other Modulating Factors of Glucocorticoid Signaling Dynamics. ( Cohen, H; Danan, D; Todder, D; Zohar, J, 2021) |
| "Ketamine is a multimodal dissociative anesthetic and analgesic that is widely used after traumatic injury." | 1.56 | Association between intravenous ketamine-induced stress hormone levels and long-term fear memory renewal in Sprague-Dawley rats. ( Berman, RY; Choi, KH; Girasek, QL; Radford, KD; Spencer, HF; Zhang, M, 2020) |
| "However, earlier animal models of type 1 diabetes are severely catabolic with very low endogenous leptin levels, unlike most patients with diabetes." | 1.56 | UCP1-independent glucose-lowering effect of leptin in type 1 diabetes: only in conditions of hypoleptinemia. ( Andersen, B; Bokhari, MH; Busby, O; Cannon, B; Conde-Frieboes, KW; Fels, JJ; Nedergaard, J; Paulsson, JF; Rakipovski, G; Raun, K; Zouhar, P, 2020) |
| "Though the association between overactive bladder (OAB) and depression was noticed years ago, the pharmaceutical market does not offer one universal drug that would cure both conditions at the same time." | 1.56 | Duloxetine reverses the symptoms of overactive bladder co-existing with depression via the central pathways. ( Kociszewski, J; Poleszak, E; Serefko, A; Szopa, A; Wiśniewski, R; Woźniak, A; Wróbel, A, 2020) |
| "Corticosterone was positively related to MDA, MDA was positively and SOD was negatively related to HOMA-IR in both groups, IL-6 showed significant positive correlations with HOMA-IR." | 1.56 | Stress adaptation disorders play a role in rat gestational diabetes with oxidative stress and glucose transporter-4 expression. ( Feng, Q; Feng, Y; Hu, J; Qu, H; Song, X; Xu, X; Yin, S, 2020) |
| "Corticosterone plasma level was increased in the CUMS compared to the non-stressed group (p < 0." | 1.56 | Valproic acid administration exerts protective effects against stress-related anhedonia in rats. ( Barati, M; Eslami, M; Goudarzi, M; Mehrabi, S; Nahavandi, A; Shahbazi, A, 2020) |
| "Corticosterone treatment induced depression-like behaviors, it increased immobility time in the TST, OFT, and FST, decreased the number of movements in OFT, and decreased sucrose consumption." | 1.56 | Oleuropein Reverses Repeated Corticosterone-Induced Depressive-Like Behavior in mice: Evidence of Modulating Effect on Biogenic Amines. ( Al-Rasheed, N; Attia, HA; Badr, AM, 2020) |
| "Long-term tooth loss is associated with the suppression of hippocampal neurogenesis and impairment of hippocampus-dependent cognition with aging." | 1.56 | Tooth loss early in life induces hippocampal morphology remodeling in senescence-accelerated mouse prone 8 (SAMP8) mice. ( Azuma, K; Iinuma, M; Kajimoto, K; Katano, M; Kubo, KY, 2020) |
| "Rats were divided into susceptible, PTSD(+), and resistant, PTSD(-), groups based on freezing duration during exposure to aversive context and the time spent in the central area in open field test one week after threefold stress experience (modified single prolonged stress)." | 1.56 | Individual susceptibility or resistance to posttraumatic stress disorder-like behaviours. ( Chmielewska, N; Kołosowska, K; Krząścik, P; Lehner, M; Maciejak, P; Płaźnik, A; Skórzewska, A; Sobolewska, A; Szyndler, J; Turzyńska, D; Wisłowska-Stanek, A, 2020) |
| "Endocrine dysregulation's role in heterotopic ossification (HO) remains unexplored." | 1.56 | Characterization of serum levels of testosterone and corticosterone in a blast and amputation rat model of heterotopic ossification. ( Atwood, RE; Bradley, MJ; Kaba, SA; Ketchum, WA; Qin, MY, 2020) |
| "Post-traumatic stress disorder (PTSD) is a stress-associated mental disorder characterized by an imbalance of neurotransmitters in response to traumatic events or fear." | 1.56 | Genistein Prevents Single Prolonged Stress-Induced Cognitive Impairment in a Post-Traumatic Stress Disorder Rat Model via Activation of the Serotonergic System. ( Choi, GM; Lee, B; Lee, H; Shim, I, 2020) |
| "Crocin (30 mg/kg) was daily intraperitoneally injected to the rats." | 1.56 | Comparative study of the protective effects of crocin and exercise on long-term potentiation of CA1 in rats under chronic unpredictable stress. ( Dastgerdi, HH; Radahmadi, M; Reisi, P, 2020) |
| "Caffeine has been known to combat stress-evoked depression." | 1.56 | New insights into the effects of caffeine on adult hippocampal neurogenesis in stressed mice: Inhibition of CORT-induced microglia activation. ( He, RR; Kurihara, H; Li, WX; Li, YF; Luo, Z; Mao, ZF; Ouyang, SH; Tu, LF; Wang, GE; Wu, YP; Zhang, QY, 2020) |
| "Depression is recognized as a highly chronic and recurrent disorder." | 1.56 | Cyclical administration of corticosterone results in aggravation of depression-like behaviors and accompanying downregulations in reelin in an animal model of chronic stress relevant to human recurrent depression. ( Allen, J; Caruncho, HJ; Kalynchuk, LE; Kulhawy, EY; Lebedeva, KA, 2020) |
| "Depression is closely linked to hypothalamus-pituitary-adrenal axis hyperactivity." | 1.56 | Antidepressant-like mechanism of honokiol in a rodent model of corticosterone-induced depression. ( Chang, HS; Duan, XH; Hu, KL; Li, LN; Li, Y; Liu, M; Yu, X; Zhang, B, 2020) |
| "Minimal hepatic encephalopathy (MHE) is characterized as cognitive deficits including memory and learning dysfunctions after liver injuries or hepatic diseases." | 1.51 | Corticosterone-mediated microglia activation affects dendritic spine plasticity and motor learning functions in minimal hepatic encephalopathy. ( Cheng, T; Han, R; So, KF; Sun, X; Xiao, J; Zhang, L; Zheng, Y, 2019) |
| "Risperidone and piracetam were found to be effective alone, while their high dose combination, produced potentiating effect in reversing the extinction deficit, behavioral alterations, altered cortical and hippocampal BDNF, IL-6, TNF-α, caspase-3, oxidative stress markers, and neurotransmitter levels." | 1.51 | Co-treatment of piracetam with risperidone rescued extinction deficits in experimental paradigms of post-traumatic stress disorder by restoring the physiological alterations in cortex and hippocampus. ( Akhtar, A; Bansal, Y; Kuhad, A; Sah, SP; Singh, R; Uniyal, A, 2019) |
| "MRL/lpr mice, an established model of systemic lupus erythematosus, show depression-like behavior." | 1.51 | Diminished responses to monoaminergic antidepressants but not ketamine in a mouse model for neuropsychiatric lupus. ( Adepu, B; Bristow, LJ; Das, ML; Dudhgaonkar, S; Kalidindi, N; Kuchibhotla, VK; Li, YW; Louis, JV; Nagar, J; Naidu, PS; Paschapur, M; Pieschl, RL; Prasad, DS; Ramarao, M; Sreedhara, MV; Srikumar, BN; Srivastava, R; Subramani, S; Vikramadithyan, RK, 2019) |
| "Besides well-known risk factors for Alzheimer's disease (AD), stress, and in particular noise stress (NS), is a lifestyle risk factor common today." | 1.51 | Gestational Stress Augments Postpartum β-Amyloid Pathology and Cognitive Decline in a Mouse Model of Alzheimer's Disease. ( Jafari, Z; Kolb, BE; Mehla, J; Mohajerani, MH, 2019) |
| " RESULTS The results showed that the extract at the dosage of 50 and 100 mg/kg significantly (p<0." | 1.51 | Antidepressive Effects of Taraxacum Officinale in a Mouse Model of Depression Are Due to Inhibition of Corticosterone Levels and Modulation of Mitogen-Activated Protein Kinase Phosphatase-1 (Mkp-1) and Brain-Derived Neurotrophic Factor (Bdnf) Expression. ( Duan, H; Gao, C; Guo, B; Kong, S; Li, D; Liang, X, 2019) |
| "Baicalein was injected intraperitoneally to TLE rats for two weeks after the onset of spontaneous recurrent seizures (SRS)." | 1.51 | Baicalein improves cognitive deficits and hippocampus impairments in temporal lobe epilepsy rats. ( Ding, JQ; Li, W; Qian, X; Wang, ZR; Zhang, M; Zhang, TY; Zheng, JJ; Zhong, JG, 2019) |
| "Corticosteroid-binding globulin (CBG), albumin and 11β-hydroxysteroid dehydrogenase (11β-HSD) enzymes play crucial roles in the bioavailability of glucocorticoids." | 1.51 | The impact of early-life stress on corticosteroid carrier protein levels and 11β-hydroxysteroid dehydrogenase 1 expression in adolescent rats. ( Chocyk, A; Majcher-Maślanka, I; Solarz, A, 2019) |
| "Post-traumatic stress disorder (PTSD) has been associated with anxiety, memory impairments, enhanced fear, and hippocampal volume loss, although the relationship between these changes remain unknown." | 1.51 | New neurons restore structural and behavioral abnormalities in a rat model of PTSD. ( Cameron, HA; Martin, L; Padmanaban, V; Rhee, D; Schoenfeld, TJ; Smith, JA; Sonti, AN, 2019) |
| "Quercetin treatment was found to significantly reduce anxiety-like behaviors in mTBI-induced mice." | 1.51 | Quercetin mitigates anxiety-like behavior and normalizes hypothalamus-pituitary-adrenal axis function in a mouse model of mild traumatic brain injury. ( Ghorbanihaghjo, A; Kosari-Nasab, M; Mesgari-Abbasi, M; Salari, AA; Shokouhi, G, 2019) |
| "Recent studies have shown that mild traumatic brain injury (mTBI) is associated with higher risk for anxiety-related disorders." | 1.51 | The blockade of corticotropin-releasing factor 1 receptor attenuates anxiety-related symptoms and hypothalamus-pituitary-adrenal axis reactivity in mice with mild traumatic brain injury. ( Bashiri, H; Kosari-Nasab, M; Sadeghi, T; Salari, AA; Shokouhi, G, 2019) |
| "Corticosterone treatment altered all parameters in behavioral tests, leading to a depressive- and anxious-like behavior." | 1.51 | Reversal effect of Riparin IV in depression and anxiety caused by corticosterone chronic administration in mice. ( Barbosa Filho, JM; Capibaribe, VCC; Chaves, RC; da Silva, DMA; de Carvalho, AMR; de Sousa, FCF; Gutierrez, SJC; Lopes, IS; Macêdo, DS; Mallmann, ASV; Oliveira, ICM; Oliveira, NF; Valentim, JT; Vasconcelos, SMM, 2019) |
| "Post traumatic stress disorder (PTSD) is one of the mental illness." | 1.51 | The anxiolytic-like effects of ginsenoside Rg2 on an animal model of PTSD. ( Gao, ZW; Ju, RL; Luo, M; Wu, SL; Zhang, WT, 2019) |
| "However, therapeutic treatments for depression or research on depression is scarce." | 1.51 | A Chronic Immobilization Stress Protocol for Inducing Depression-Like Behavior in Mice. ( Kim, HJ; Lee, DK; Son, H; Yang, JH, 2019) |
| "Hypertension is a common chronic disease, and it is the strongest risk factor for cardiovascular disease." | 1.51 | UPLC-QTOF/MS-based metabolomics reveals the mechanism of chronic unpredictable mild stress-induced hypertension in rats. ( Lan, F; Liu, M; Peng, XD; Sun, JC; Tan, X; Wang, R; Wang, WZ; Wang, YK; Wu, Q; Xia, DM, 2019) |
| "The neuroendocrine background of acute sleep fragmentation in obstructive sleep apnea and sleep fragmentation involvement in psychiatric comorbidities, common in these patients, are still largely unknown." | 1.51 | Short-term sleep fragmentation enhances anxiety-related behavior: The role of hormonal alterations. ( Ademovic, A; Grubac, Z; Hrncic, D; Macut, D; Petronijevic, N; Rasic-Markovic, A; Stanojlovic, O; Sutulovic, N; Velimirovic, M, 2019) |
| "lacteus as an antioxidant in the treatment of fatigue-related diseases." | 1.51 | Studies on the anti-fatigue activities of Irpex lacteus polysaccharide-enriched extract in mouse model. ( Cai, G; Hu, W; Li, C; Li, L; Liu, Y; Wang, D; Wang, J, 2019) |
| "Nicotine responses were assessed with acute effects on body temperature, corticosterone production, locomotor activity, and voluntary oral nicotine consumption." | 1.48 | Adolescent chronic variable social stress influences exploratory behavior and nicotine responses in male, but not female, BALB/cJ mice. ( Baker, AN; Caruso, MJ; Caulfield, JI; Cavigelli, SA; Kamens, HM; Reiss, DE; Thomas, JL, 2018) |
| "Agmatine is an endogenous neuromodulator that has been shown to have beneficial effects in the central nervous system, including antidepressant-like effects in animals." | 1.48 | Antidepressant and pro-neurogenic effects of agmatine in a mouse model of stress induced by chronic exposure to corticosterone. ( Azevedo, DP; Brocardo, PS; Fraga, DB; Gil-Mohapel, J; Melleu, FF; Neis, VB; Olescowicz, G; Rodrigues, ALS; Rosa, PB, 2018) |
| "Oxytocin (OXT) has been considered as a neuroregulator mediating social behaviors and stress-related disorders." | 1.48 | Injection of oxytocin into paraventricular nucleus reverses depressive-like behaviors in the postpartum depression rat model. ( Li, H; Li, X; Liu, B; Shi, C; Wang, H; Wang, T; Wang, Y; Wu, Y; Xu, ZD; Yang, Y; Zhang, P, 2018) |
| "Binge eating is a specific form of overeating characterized by intermittent, excessive eating." | 1.48 | Housing conditions modulate the reinforcing properties of cocaine in adolescent mice that binge on fat. ( Aguilar, MA; Blanco-Gandía, MC; Miñarro, J; Montagud-Romero, S; Rodríguez-Arias, M, 2018) |
| "Moreover, chemical carcinogenesis can promote stressor-like effects with hormonal changes in the tissue microenvironment, which may be associated to tumor progression." | 1.48 | Stress hormones concentrations in the normal microenvironment predict risk for chemically induced cancer in rats. ( Bernabé, DG; Biasoli, ÉR; de Andrade, M; de Oliveira, SHP; Dos Santos, PSP; Ferreira, JZ; Lopes, FYK; Miyahara, GI; Soubhia, AMP; Sundefeld, MLMM; Valente, VB; Verza, FA, 2018) |
| "Post-traumatic stress disorder (PTSD) is a common consequence of exposure to a life-threatening event." | 1.48 | Influence of early stress on memory reconsolidation: Implications for post-traumatic stress disorder treatment. ( Benkahoul, A; Birmes, P; Ferry, B; Roullet, P; Villain, H, 2018) |
| " At the end of dosing schedule, neurobehavioral tests were conducted; followed by mechanistic evaluation through biochemical analysis, RTPCR and western blot in serum and hippocampus." | 1.48 | Antidepressant activity of vorinostat is associated with amelioration of oxidative stress and inflammation in a corticosterone-induced chronic stress model in mice. ( Js, IC; Kv, A; Lahkar, M; Madhana, RM; Naidu, VGM; Sinha, S, 2018) |
| "Glucocorticoids (GCs) are used for acute respiratory distress syndrome (ARDS) to improve or prevent lung injury." | 1.48 | Glucocorticoid receptor gene expression in a CLP-induced ARDS-like rat model treated with dexamethasone and metyrapone. ( Barchuk, AR; Incerpi, EK; Ramos Lopes, AC; Ruginsk, SG; Soncini, R; Vieira, J, 2018) |
| "Post-traumatic stress disorder (PTSD) is the serious psychiatric disorder." | 1.48 | Anxiolytic-like effects of paeoniflorin in an animal model of post traumatic stress disorder. ( Chai, XM; Chen, JS; Fan, QH; He, JL; Liu, X; Qiu, ZK; Xiao, W; Ye, WH; Zeng, J, 2018) |
| "Baicalin treatment inhibited APPL2/GR signaling pathway and improved neurogenesis at SVZ, OB, and hippocampus in APPL2 Tg mice and chronic corticosterone-induced depression mouse model." | 1.48 | Baicalin Modulates APPL2/Glucocorticoid Receptor Signaling Cascade, Promotes Neurogenesis, and Attenuates Emotional and Olfactory Dysfunctions in Chronic Corticosterone-Induced Depression. ( Deng, R; Du, Q; Gao, C; Li, W; Shen, J; Wang, Q; Xu, A, 2018) |
| "Corticosterone levels were evaluated in plasma under basal and stress conditions, and within hippocampus together with 11β-dehydrocorticosterone to assess 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) activity." | 1.48 | Insulin treatment partially prevents cognitive and hippocampal alterations as well as glucocorticoid dysregulation in early-onset insulin-deficient diabetic rats. ( Barat, P; Beauvieux, MC; Bouzier-Sore, AK; Brossaud, J; Campas, MN; Corcuff, JB; Ducroix-Crepy, C; Ferreira, G; Helbling, JC; Marissal-Arvy, N; Moisan, MP; Semont, A; Touyarot, K; Vancassel, S, 2018) |
| "Depression is one of the most frequent neuropsychiatric diseases in the western world and its physiological causes are not yet fully understood." | 1.48 | Cholecalciferol counteracts depressive-like behavior and oxidative stress induced by repeated corticosterone treatment in mice. ( Camargo, A; da Silva, EB; Dalmagro, AP; Rikel, L; Simão da Silva, KAB; Zeni, ALB, 2018) |
| "Early mortality was primarily due to polytrauma and change in the animal's biochemical parameters appeared at t4 post trauma." | 1.48 | Effect of acute restraint stress in a polytrauma rat model. ( Arnaud, F; Chen, Y; Maudlin-Jeronimo, E; McCarron, R; Pappas, G, 2018) |
| "Because memory deficits are also common in clinical populations with GWI, we examined the effects of PB and stress on contextual fear conditioning." | 1.48 | Pathophysiology in a model of Gulf War Illness: Contributions of pyridostigmine bromide and stress. ( Grillo, CA; Macht, VA; Reagan, LP; Wilson, MA; Wood, CS; Woodruff, JL, 2018) |
| "Corticosterone pre-treatment generated oxidative stress, altering antioxidant enzymes in the nervous tissue." | 1.48 | Antioxidant and antidepressant-like effects of Eugenia catharinensis D. Legrand in an animal model of depression induced by corticosterone. ( Alberton, MD; Barauna, SC; Brueckheimer, MB; de Albuquerque, CAC; de Gasper, AL; de Melo, DFM; Delwing-Dal Magro, D; Delwing-De Lima, D; Döhler, AW; Harger, MC; Maia, TP; Micke, GA; Sala, GABN; Siebert, DA, 2018) |
| "Oxytocin (OXT) is a neuropeptide that regulates sexual reproduction and social interaction and has recently earned specific attention due to its role in adjusting neurobiological and behavioral correlates of PTSD; however, the mechanism by which this is achieved remains unclear." | 1.48 | Effects of Oxytocin on Fear Memory and Neuroinflammation in a Rodent Model of Posttraumatic Stress Disorder. ( Chen, CC; Lin, CC; Liu, YP; Tzeng, NS; Wang, SC, 2018) |
| " In our study, we aimed to investigate whether chronic administration of oxytocin (10 IU/400μL/day for 14days, s." | 1.46 | Oxytocin in corticosterone-induced chronic stress model: Focus on adrenal gland function. ( Dronjak, S; Ignjatović, S; Jovanović, P; Marković, B; Mirković, D; Pešić, V; Plećaš-Solarović, B; Stanić, D; Đorđević, T, 2017) |
| "Some patients with psychiatric disorders show hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis." | 1.46 | A Protocol for Generation of a Corticosterone Model of Psychiatric Disorders. ( Guest, PC, 2017) |
| "Insulin resistance has been identified as the key mechanism linking depression and diabetes." | 1.46 | Curcumin reverses the depressive-like behavior and insulin resistance induced by chronic mild stress. ( Li, YC; Li, YJ; Qiao, JY; Shen, JD; Wei, Y, 2017) |
| "Corticosterone levels were detected by ELISA, and the hippocampal NR1 and NR2A were measured by RT-PCR and Western blot analysis." | 1.46 | Distinct behavioral and brain changes after different durations of the modified multiple platform method on rats: An animal model of central fatigue. ( Guo, S; Han, C; Li, F; Li, W; Liu, J; Liu, Y; Ma, J; Mao, Y; Song, Y, 2017) |
| " This study aimed to investigate the effects of mirtazapine (MIRT) alone and combined with alpha-lipoic acid (ALA) against corticosterone (CORT) induced behavioral and oxidative alterations." | 1.46 | Brain antioxidant effect of mirtazapine and reversal of sedation by its combination with alpha-lipoic acid in a model of depression induced by corticosterone. ( de Oliveira, AA; de Sousa, CNS; de Sousa, LC; Honório Júnior, JER; Macedo, D; Maes, M; Medeiros, IDS; Oliveira, TQ; Patrocínio, CFV; Vasconcelos, GS; Vasconcelos, SMM, 2017) |
| "Ketamine and etomidate inhibit the enzyme expression and activity of the adrenal gland at the early stage." | 1.46 | Ketamine and Etomidate Down-regulate the Hypothalamic-Pituitary-Adrenal Axis in an Endotoxemic Mouse Model. ( Besnier, E; Castel, H; Clavier, T; Compere, V; Dureuil, B; Lefevre-Scelles, A; Morin, F; Selim, J; Tamion, F; Tonon, MC, 2017) |
| "A common familial Alzheimer's disease transgenic model showed heightened levels of the stress hormone, corticosterone." | 1.46 | Environmental novelty exacerbates stress hormones and Aβ pathology in an Alzheimer's model. ( Fernandez-Martos, CM; King, AE; Stuart, KE; Summers, MJ; Vickers, JC, 2017) |
| " Chronic administration of AS101 significantly reduced anxiety-like behavior of Sub mice in the elevated plus maze, according to both time spent and entries to open arms, relative to vehicle-treated controls." | 1.46 | The immunomodulatory tellurium compound ammonium trichloro (dioxoethylene-O,O') tellurate reduces anxiety-like behavior and corticosterone levels of submissive mice. ( Gross, M; Kenigsbuch-Sredni, D; Pinhasov, A; Sredni, B; Stanciu, E, 2017) |
| "Post-traumatic stress disorder (PTSD) is characterized by memory disturbances following trauma." | 1.46 | Predator odor evokes sex-independent stress responses in male and female Wistar rats and reduces phosphorylation of cyclic-adenosine monophosphate response element binding protein in the male, but not the female hippocampus. ( Barrileaux, B; Hajmurad, S; Homiack, D; Kreutz, MR; O'Cinneide, E; Schrader, LA; Stanley, M, 2017) |
| "Nonalcoholic fatty liver disease (NAFLD), a common prelude to cirrhosis and hepatocellular carcinoma, is the most common chronic liver disease worldwide." | 1.46 | Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling. ( Aronow, BJ; Cappelletti, M; Chan, CC; Divanovic, S; Giles, DA; Graspeuntner, S; Haslam, DB; Hogan, SP; Iwakura, Y; Kahn, CR; Karns, R; Karp, CL; Klarquist, J; Lawson, MJ; Moreno-Fernandez, ME; Mukherjee, R; Reynaud, D; Rupp, J; Shanmukhappa, SK; Sheridan, R; Sina, C; Softic, S; Stankiewicz, TE; Steinbrecher, KA; Stemmer, K; Sünderhauf, A; Wu, D, 2017) |
| "Immediately after the sleep deprivation protocol, animals locomotor activity was evaluated and serum and brain samples was extracted to evaluation of corticosterone and adrenocorticotropic hormone circulating levels, oxidative stress parameters and citokynes levels." | 1.46 | Lithium ameliorates sleep deprivation-induced mania-like behavior, hypothalamic-pituitary-adrenal (HPA) axis alterations, oxidative stress and elevations of cytokine concentrations in the brain and serum of mice. ( Carvalho, AF; Dal-Pizzol, F; Dal-Pont, G; Gava, FF; Peterle, BR; Quevedo, J; Resende, WR; Sangaletti-Pereira, H; Valvassori, SS; Varela, RB, 2017) |
| "We demonstrate that ozone-induced lung injury and neutrophilic inflammation require the presence of circulating epinephrine and corticosterone, which transcriptionally regulates signaling mechanisms involved in this response." | 1.46 | Adrenal-derived stress hormones modulate ozone-induced lung injury and inflammation. ( Fisher, A; Henriquez, A; House, J; Kodavanti, UP; Ledbetter, AD; Miller, DB; Ren, H; Schladweiler, MC; Snow, SJ; Wright, F, 2017) |
| "Weight gain was similar across the three diets while visceral fat mass was elevated by the two HFDs." | 1.46 | Saturated high-fat feeding independent of obesity alters hypothalamus-pituitary-adrenal axis function but not anxiety-like behaviour. ( Alquier, T; Daneault, C; Décarie-Spain, L; Fulton, S; Hryhorczuk, C; Rosiers, CD; Sharma, S, 2017) |
| "Depression is a recurrent neuropsychiatric disorder that affects millions of individuals worldwide and impact negatively on the patients' social functions and quality of life." | 1.46 | Methyl jasmonate attenuated lipopolysaccharide-induced depressive-like behaviour in mice. ( Adebesin, A; Adeoluwa, OA; Eduviere, AT; Umukoro, S, 2017) |
| "Taken together, transition to alcohol dependence could be accompanied by alterations in mPFC stress-related pathways that may increase negative emotional symptoms and increase vulnerability to relapse." | 1.46 | Abstinence from prolonged ethanol exposure affects plasma corticosterone, glucocorticoid receptor signaling and stress-related behaviors. ( Contet, C; Fannon, MJ; Guevara, J; Mandyam, CD; Nguyen, TB; Schmeichel, BE; Sidhu, H; Somkuwar, SS; Vendruscolo, LF; Zorrilla, EP, 2017) |
| "Corticosterone level was inversely correlated with QUICKI (r = -0." | 1.46 | Effects of high-intensity interval versus mild-intensity endurance training on metabolic phenotype and corticosterone response in rats fed a high-fat or control diet. ( Huang, G; McCormick, BP; Shen, Y; Song, T; Xu, X, 2017) |
| "Recently, depression has been envisioned as more than an alteration in neurotransmitters centered around receptor signaling pathways." | 1.46 | Fluoxetine coupled with zinc in a chronic mild stress model of depression: Providing a reservoir for optimum zinc signaling and neuronal remodeling. ( Omar, NN; Tash, RF, 2017) |
| "Depression is one of the important world-wide health problems." | 1.46 | Can Ocimum basilicum relieve chronic unpredictable mild stress-induced depression in mice? ( Ali, S; Ayuob, NN; El-Mansy, AA; Firgany, AEL, 2017) |
| "Comorbid depression was induced by five inescapable foot-shocks (2mA, 2ms duration) at 10s intervals on days 1, 5, 7, and 10." | 1.46 | Metformin and ascorbic acid combination therapy ameliorates type 2 diabetes mellitus and comorbid depression in rats. ( Kumar, M; Nayak, PK; Shivavedi, N; Tej, GNVC, 2017) |
| "Physical fatigue was induced by sleep deprivation and forced exercise in a rotating cage." | 1.46 | A Novel Animal Model Simulating the Beginning of Combat Exposure. ( Cheon, K; Heo, Y; Kim, CY; Kim, D; Koo, H, 2017) |
| "A mouse model has been developed to study the effect of dietary fat combined with food deprivation periods on palatable food seeking and on the expression of three potential addiction biomarkers in the nucleus accumbens: fumarate hydratase (FH), ATP synthase subunit alpha (ATP5a1) and transketolase (TKT)." | 1.46 | A high-fat diet combined with food deprivation increases food seeking and the expression of candidate biomarkers of addiction. ( Alguacil, LF; Galiana-Simal, A; García-Rojo, M; González-Martín, C; Pérez-Ortiz, JM; Salas, E, 2017) |
| "Depression has become a common public health problem that is showing increasing prevalence." | 1.46 | Evaluation of the antidepressant-like effect of musk in an animal model of depression: how it works. ( Ayuob, NN, 2017) |
| "Sepsis was induced using cecal ligation and puncture (CLP) in wild-type (WT) mice, IL-18 knockout (KO) mice, and IL-18 KO mice pretreated with recombinant IL-18." | 1.46 | Interleukin-18 Reduces Blood Glucose and Modulates Plasma Corticosterone in a Septic Mouse Model. ( Inoue, T; Ishikawa, M; Kotani, J; Usami, M; Usami, Y; Yamashita, H, 2017) |
| "Corticosterone levels were increased in the stressed rats with dentin erosion and also corroborate present findings." | 1.46 | Stress and its role in the dentin hypersensitivity in rats. ( Bergamini, MR; Bernardi, MM; Ciaramicoli, MT; Kabadayan, F; Kodama, RM; Saraceni, CH; Suffredini, IB, 2017) |
| "Etazolate (ETZ) is a new generation PDE4 inhibitor with encouraging safety and tolerance profiles." | 1.46 | Molecular modifications by regulating cAMP signaling and oxidant-antioxidant defence mechanisms, produce antidepressant-like effect: A possible mechanism of etazolate aftermaths of impact accelerated traumatic brain injury in rat model. ( Bhatt, S; Jindal, A; Mahesh, R; Pandey, D, 2017) |
| "Visceral pain has a greater emotional component than somatic pain." | 1.46 | Mild Social Stress in Mice Produces Opioid-Mediated Analgesia in Visceral but Not Somatic Pain States. ( Baeyens, JM; Cervero, F; Cobos, EJ; Coderre, TJ; Gonzalez-Cano, R; Lehmann, M; Pitcher, MH; Vincent, K, 2017) |
| "Peak corticosterone levels were 49% lower (p < 0." | 1.46 | Simvastatin treatment aggravates the glucocorticoid insufficiency associated with hypocholesterolemia in mice. ( Hoekstra, M; Nahon, JE; Ouweneel, AB; van der Sluis, RJ; Van Eck, M, 2017) |
| "Tinnitus and hyperacusis are common and potentially serious hearing disorders associated with noise-, age- or drug-induced hearing loss." | 1.46 | Tinnitus and hyperacusis: Contributions of paraflocculus, reticular formation and stress. ( Auerbach, BD; Chen, GD; Chen, YC; Manohar, S; Radziwon, K; Salvi, R, 2017) |
| " A dose-response study showed that 4 weeks of CORT exposure at 35 μg/ml in the drinking water enhanced the emotionality score of female mice, but with a very small size effect." | 1.46 | Chronic corticosterone administration effects on behavioral emotionality in female c57bl6 mice. ( David, DJ; Gardier, AM; Guilloux, JP; Mekiri, M, 2017) |
| "Sepsis and septic shock are commonly present in the ICU and accompanied by significant morbidity, mortality, and cost." | 1.43 | Mortality of Septic Mice Strongly Correlates With Adrenal Gland Inflammation. ( Bornstein, S; Dröse, S; Heerdegen, L; Jennewein, C; Kanczkowski, W; Kantharajah, A; Scheller, B; Tran, N; Zacharowski, K, 2016) |
| "Post-traumatic stress disorder (PTSD), a highly debilitating neuropsychiatric disorder characterized by intense fear of trauma-related stimuli, often occurs in individuals that have only witnessed a traumatic event." | 1.43 | Vicarious social defeat stress: Bridging the gap between physical and emotional stress. ( Alcantara, LF; Bolaños-Guzmán, CA; Parise, EM; Sial, OK; Warren, BL, 2016) |
| "Major depression is a multifactorial disease, involving both environmental and genetic risk factors." | 1.43 | SLC6A15, a novel stress vulnerability candidate, modulates anxiety and depressive-like behavior: involvement of the glutamatergic system. ( Balsevich, G; Chen, A; Dournes, C; Hartmann, J; Holsboer, F; Labermaier, C; Masana, M; Müller, MB; Santarelli, S; Schmidt, MV; Uribe, A; Wagner, KV, 2016) |
| "Sulforaphane (SFN) is a natural compound with antioxidative, anti-inflammatory and neuroprotective activities." | 1.43 | Sulforaphane produces antidepressant- and anxiolytic-like effects in adult mice. ( Gao, Q; Gao, Y; Liang, Y; Ma, Y; Shi, H; Wang, X; Wu, S; Xi, Y; Zhao, P, 2016) |
| "Brain edema was measured on day 5 by MRI, histochemical staining of brain sections and tissue water content determination (n=7, each experiment)." | 1.43 | Treadmill exercise ameliorates ischemia-induced brain edema while suppressing Na⁺/H⁺ exchanger 1 expression. ( Aono, H; Choudhury, ME; Fujita, T; Islam, A; Mise, A; Miyanishi, K; Nishioka, R; Sugimoto, K; Takahashi, H; Takeda, H; Tanaka, J; Yano, H, 2016) |
| "Depression is associated with hypothalamic-pituitary-adrenal (HPA) axis hyperactivity and testosterone exerts suppressive effects on the HPA axis." | 1.43 | Testosterone has antidepressant-like efficacy and facilitates imipramine-induced neuroplasticity in male rats exposed to chronic unpredictable stress. ( Chow, C; Galea, LA; Hamson, DK; Lieblich, SE; Tehrani, A; Wainwright, SR; Workman, JL, 2016) |
| " Night-time dosing of thiazides may be particularly beneficial in patients with modest glucocorticoid excess." | 1.43 | Glucocorticoids Induce Nondipping Blood Pressure by Activating the Thiazide-Sensitive Cotransporter. ( Al-Dujaili, EA; Bailey, MA; Dear, JW; Dhaun, N; Flatman, PW; Howarth, AR; Hunter, RW; Ivy, JR; Oosthuyzen, W; Peltz, TS; Webb, DJ, 2016) |
| "Fluoxetine treatment showed limited behavioral and neuroendocrine efficacy, however it reduced microglial (Iba-1) expression, and increased cell proliferation, neurogenesis (via cell survival), and the expression of the polysialylated neuronal cell adhesion molecule (PSA-NCAM) in the dentate gyrus, although these effects varied by region (dorsal, ventral) and ovarian status." | 1.43 | Ovarian hormones, but not fluoxetine, impart resilience within a chronic unpredictable stress model in middle-aged female rats. ( Chaiton, JA; Galea, LAM; Lieblich, SE; Mahmoud, R; Wainwright, SR, 2016) |
| " The propofol self-administration model was established by a fixed ratio 1 (FR1) schedule of reinforced dosing over successive 14days in rats." | 1.43 | Glucocorticoid receptor mediated the propofol self-administration by dopamine D1 receptor in nucleus accumbens. ( Chen, Z; Dong, Z; Ge, RS; Lian, Q; Liang, Y; Lin, W; Wang, B; Wang, S; Wu, B; Zhang, G, 2016) |
| " We found that exposure to foot shock induced long-lasting behavioral deficiencies in mice, including freezing and anxiety-like behaviors, that were significantly ameliorated by the long-term administration of GLYX-13 (5 or 10 mg/kg)." | 1.43 | Anxiolytic effects of GLYX-13 in animal models of posttraumatic stress disorder-like behavior. ( Jin, ZL; Li, YF; Liu, JX; Liu, X; Ran, YH; Tang, Y; Xiong, J; Zhang, LM; Zheng, YY, 2016) |
| "We suggest that the genetic predisposition for high stress reactivity interacts with ELS exposure by disturbing the suppression of corticosterone release during a critical period of brain development, thus exerting lasting programming effects on the HPA axis, presumably via epigenetic mechanisms." | 1.43 | Genetic predisposition for high stress reactivity amplifies effects of early-life adversity. ( Burgstaller, J; Chen, A; Matthes, M; McIlwrick, S; Rechenberg, A; Schwarzbauer, T; Touma, C, 2016) |
| "Depression is a heterogeneous disorder characterized by alterations at psychological, behavioural, physiological, neurophysiological, and neurochemical levels." | 1.43 | Simultaneous Changes in Sleep, qEEG, Physiology, Behaviour and Neurochemistry in Rats Exposed to Repeated Social Defeat Stress. ( Ahnaou, A; Drinkenburg, WH, 2016) |
| "Pneumococcal meningitis is a life-threatening infection of the central nervous system (CNS) with a high mortality rate." | 1.43 | Depression-Like Adult Behaviors may be a Long-Term Result of Experimental Pneumococcal Meningitis in Wistar Rats Infants. ( Barichello, T; Dominguini, D; Generoso, JS; Jornada, LK; Quevedo, J; Sharin, VS; Simões, LR; Souza, LB; Teixeira, AL; Valvassori, SS, 2016) |
| "In patients with Alzheimer's disease, in addition to the core symptoms, i." | 1.43 | Involvement of hippocampal excitability in amyloid β-induced behavioral and psychological symptoms of dementia. ( Adlard, PA; Bush, AI; Ide, K; Takeda, A; Tamano, H, 2016) |
| "Musk has an antidepressant-like effect in an animal model of depression, so it is advisable to assess its efficacy in people continually exposed to stressors." | 1.43 | The antidepressant effect of musk in an animal model of depression: a histopathological study. ( Ahmed, SM; Ali, SS; Ayuob, NN; El Wahab, MGA; Suliaman, M, 2016) |
| "We demonstrate that depression is associated with decreased gut microbiota richness and diversity." | 1.43 | Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat. ( Beers, S; Borre, Y; Clarke, G; Cryan, JF; Deane, J; Dinan, TG; El Aidy, S; Fitzgerald, P; Hoban, AE; Kelly, JR; Kennedy, PJ; Moloney, G; O' Brien, C; Patterson, E; Ross, P; Scott, K; Scott, L; Stanton, C, 2016) |
| "Major depression is a life threatening neuropsychiatric disorder that produces mental illness and major cause of morbidity." | 1.43 | Neuroprotective, Neurotrophic and Anti-oxidative Role of Bacopa monnieri on CUS Induced Model of Depression in Rat. ( Kumar, S; Mondal, AC, 2016) |
| " Chronic administration of BB effectively reversed these alterations." | 1.43 | Bilobalide alleviates depression-like behavior and cognitive deficit induced by chronic unpredictable mild stress in mice. ( Shui, L; Song, Z; Tai, F; Wang, S; Wu, R, 2016) |
| "Tinnitus is a devastating auditory disorder impacting a growing number of people each year." | 1.43 | Acute high-intensity noise induces rapid Arc protein expression but fails to rapidly change GAD expression in amygdala and hippocampus of rats: Effects of treatment with D-cycloserine. ( Kapolowicz, MR; Thompson, LT, 2016) |
| "Indeed, here we found that cardiac hypertrophy and heart failure induced by TAC were associated with depression-like behaviors concomitant with downregulation of σ1R expression in brain 6 weeks after surgery." | 1.43 | Corticosteroids Mediate Heart Failure-Induced Depression through Reduced σ1-Receptor Expression. ( Bhuiyan, MS; Fukunaga, K; Han, F; Hasegawa, H; Kanai, H; Shinoda, Y; Tagashira, H; Zhang, C, 2016) |
| "Depression is the most common form of mental disability in the world." | 1.43 | Anhedonia but not passive floating is an indicator of depressive-like behavior in two chronic stress paradigms. ( Freiman, SV; Gulyaeva, NV; Lazareva, NA; Levchenko, OA; Levshina, IP; Novikova, MR; Onufriev, MV; Stepanichev, MY; Tishkina, AO, 2016) |
| "Corticosterone levels were significantly increased compared to control values (p<0." | 1.43 | Chronic unpredictable mild stress paradigm in male Wistar rats: effect on anxiety- and depressive-like behavior. ( Belovičová, K; Bögi, E; Koprdova, R; Mach, M; Okuliarová, M; Sedláčková, N; Ujházy, E, 2016) |
| "Due to the complex nature of Alzheimer's disease, multi-target-directed ligand approaches are one of the most promising strategies in the search for effective treatments." | 1.42 | Synthesis of new N-benzylpiperidine derivatives as cholinesterase inhibitors with β-amyloid anti-aggregation properties and beneficial effects on memory in vivo. ( Bajda, M; Brus, B; Czerwińska, P; Filipek, B; Gobec, S; Malawska, B; Sałat, K; Więckowska, A; Więckowski, K, 2015) |
| "Obesity is a major risk factor for the development of type 2 diabetes and other debilitating diseases." | 1.42 | Changes in morphology and function of adrenal cortex in mice fed a high-fat diet. ( Bornstein, SR; Chavakis, T; Eaton, S; Eisenhofer, G; Lamounier-Zepter, V; Mateska, I; Peitzsch, M; Swierczynska, MM, 2015) |
| "Endometriosis was surgically induced in female Sprague-Dawley rats before exposing animals to a controllable (submerged platform) or uncontrollable (no platform) swim stress protocol." | 1.42 | Stress management affects outcomes in the pathophysiology of an endometriosis model. ( Appleyard, CB; Bayona, M; Cruz, ML; Flores, I; Hernández, S; Thompson, KJ, 2015) |
| " The relative efficacy of pre versus post administration of corticosterone and high versus low dose of corticosterone on stress-induced exaggeration of innate fear response and stress-retarded body weight growth indicate that exogenous corticosterone administration within an appropriate time window and dosage are efficacious in diminishing traumatic stress induced pathophysiological processes." | 1.42 | Corticosterone mitigates the stress response in an animal model of PTSD. ( Benedek, D; Jia, M; Li, H; Li, X; Smerin, SE; Ursano, R; Xing, G; Zhang, L, 2015) |
| "Sepsis was induced by cecal ligation and puncture (CLP) in wild type (WT) and OPN gene knockout (OPN(-/-) ) mice." | 1.42 | Osteopontin is associated with inflammation and mortality in a mouse model of polymicrobial sepsis. ( Fortis, S; Haitsma, JJ; Khadaroo, RG; Zhang, H, 2015) |
| "Depression is a common psychiatric disorder associated with chronic stress." | 1.42 | Insulin-like growth factor 2 mitigates depressive behavior in a rat model of chronic stress. ( Cao, WY; Dai, RP; Duan, J; Hu, ZL; Li, CQ; Li, F; Luo, YW; Wang, XQ; Xu, Y; Zhang, JY; Zhong, XL; Zhou, M, 2015) |
| "SPS represents a preclinical model of PTSD-related sleep-wake and qEEG disturbances with underlying alterations in neurotransmitter systems known to modulate both sleep-wake architecture and the neural fear circuitry." | 1.42 | A rodent model of traumatic stress induces lasting sleep and quantitative electroencephalographic disturbances. ( Bubser, M; Conn, PJ; Gong, X; Gould, RW; Grannan, M; Ivarsson, M; Jones, CK; Lindsley, CW; Nedelcovych, MT; Thompson, AT; Zhan, X, 2015) |
| "Microvascular ischemia is linked to cardiovascular disease pathology, as well as alterations in mood and cognition." | 1.42 | Microemboli alter the acute stress response and cause prolonged expression of MCP-1 in the hippocampus. ( Neigh, GN; Nemeth, CL, 2015) |
| "The range of defects that fall within fetal alcohol spectrum disorder (FASD) includes persistent behavioral problems, with anxiety and depression being two of the more commonly reported issues." | 1.42 | Hypothalamic-pituitary-adrenal axis and behavioral dysfunction following early binge-like prenatal alcohol exposure in mice. ( Fish, EW; O'Leary-Moore, SK; Parnell, SE; Sulik, KK; Wieczorek, L, 2015) |
| "Both corticosterone and cAMP were quantitatively measured using a commercial enzyme-linked immunosorbent assay (ELISA)." | 1.42 | Granulocyte-colony stimulating factor activates JAK2/PI3K/PDE3B pathway to inhibit corticosterone synthesis in a neonatal hypoxic-ischemic brain injury rat model. ( Charles, MS; Doycheva, DM; Drunalini Perera, PN; Tang, J, 2015) |
| "In a group of 92 veterans with PTSD, we observed significantly higher Clinician-Administered PTSD Scale and PTSD Checklist scores in E2+ individuals, as well as alterations in salivary cortisol levels." | 1.42 | ApoE2 Exaggerates PTSD-Related Behavioral, Cognitive, and Neuroendocrine Alterations. ( Bidiman, E; Johnson, LA; Marzulla, T; Raber, J; Wahbeh, H; Weber, S; Zuloaga, DG, 2015) |
| "Post-traumatic stress disorder (PTSD) is a stress-related mental disorder caused by traumatic experiences." | 1.42 | Long-term effects of early adolescent stress: dysregulation of hypothalamic-pituitary-adrenal axis and central corticotropin releasing factor receptor 1 expression in adult male rats. ( Jiang, H; Li, C; Liu, D; Liu, Y; Lu, C; Pan, F; Yin, S, 2015) |
| "Corticosterone was injected intraperitoneally 10 min before the test trial which was performed either 1 or 24h after the sample trial." | 1.42 | Acute restraint stress and corticosterone transiently disrupts novelty preference in an object recognition task. ( González-Martínez, L; Lamprea, MR; Múnera, A; Torres-Berrio, A; Vargas-López, V, 2015) |
| "Chronic pain and depression are two complex states that often coexist in the clinical setting and traditional antidepressants and analgesics have shown limited clinical efficacy." | 1.42 | m-Trifluoromethyl-diphenyl diselenide, a multi-target selenium compound, prevented mechanical allodynia and depressive-like behavior in a mouse comorbid pain and depression model. ( Brüning, CA; Duarte, MM; Gai, BM; Martini, F; Nogueira, CW; Sampaio, TB; Soares, SM, 2015) |
| "Depression during pregnancy has been linked to in utero stress and is associated with long-lasting symptoms in offspring, including anxiety, helplessness, attentional deficits, and social withdrawal." | 1.42 | Prenatal stress, regardless of concurrent escitalopram treatment, alters behavior and amygdala gene expression of adolescent female rats. ( Bourke, CH; Ehrlich, DE; Hazra, R; Jairam, N; Neigh, GN; Nemeth, CL; Owens, MJ; Rainnie, DG; Rowson, S; Ryan, SJ; Sholar, CA; Stowe, ZN, 2015) |
| "Intra-abdominal hypertension and abdominal compartment syndrome (IAH/ACS) are life-threatening conditions and caused by several clinical status." | 1.42 | Effects of intra-abdominal pressure on adrenal gland function and morphology in rats. ( Akkapulu, N; Cetinkaya, E; Dogrul, AB; Hayran, M; Kulac, I; Tezel, GG; Tirnaksiz, MB; Yorganci, K, 2015) |
| "The corticosterone levels were not significantly changed following REM-SD neither in intact nor in GDX male rats." | 1.42 | Effect of castration on the susceptibility of male rats to the sleep deprivation-induced impairment of behavioral and synaptic plasticity. ( Ghadiri, T; Ghazvini, H; Hajali, V; Saadati, H; Shabani, M; Sheibani, V; Valizadeh, T, 2015) |
| " Chronic administration of lithium chloride or valproic acid, two clinically effective mood stabilizers, reverses the majority of these behavioral abnormalities." | 1.42 | Mice heterozygous for cathepsin D deficiency exhibit mania-related behavior and stress-induced depression. ( Duan, S; Han, Y; Li, X; Lou, H; Lu, Y; Zhen, X; Zhou, R; Zhu, L, 2015) |
| "A rat model of intrauterine growth retardation (IUGR) was established by PEE (4g/kg·d)." | 1.42 | Prenatal ethanol exposure-induced adrenal developmental abnormality of male offspring rats and its possible intrauterine programming mechanisms. ( He, Z; Huang, H; Kou, H; Liu, L; Shen, L; Wang, H; Zhu, C, 2015) |
| " In recent years, pediatric acute lymphoblastic leukemia clinical trials have used discontinuous rather than continuous dosing of dexamethasone in an effort to reduce the incidence of osteonecrosis." | 1.42 | Antileukemic Efficacy of Continuous vs Discontinuous Dexamethasone in Murine Models of Acute Lymphoblastic Leukemia. ( Cai, X; Cheng, C; Evans, WE; Janke, LJ; Jeha, S; Kamdem Kamdem, L; Karol, SE; Paugh, SW; Payton, MA; Pui, CH; Ramsey, LB; Relling, MV; Williams, RT, 2015) |
| "Corticosterone was increased in the SD group compared with the control group, and this increase was minimized in the RT+SD group." | 1.42 | Resistance training minimizes catabolic effects induced by sleep deprivation in rats. ( Antunes, HK; Dáttilo, M; de Mello, MT; de Moraes, WM; Giampá, SQ; Lee, KS; Medeiros, A; Mônico-Neto, M; Phillips, SM; Souza, Hde S; Tufik, S, 2015) |
| "Corticosterone level was measured using ELISA Kit while BDNF levels were assessed using ELISA Chemikine TM BDNF kit." | 1.42 | Biochemical and cognitive impairments observed in animal models of schizophrenia induced by prenatal stress paradigm or methylazoxymethanol acetate administration. ( Giermaziak, W; Kus, K; Murawiecka, P; Nowakowska, E; Ratajczak, P; Słodzińska, I, 2015) |
| "Myricetin treatment improved activities of glutathione peroxidase (GSH-PX) in the hippocampus of stressed mice." | 1.42 | Myricetin Attenuates Depressant-Like Behavior in Mice Subjected to Repeated Restraint Stress. ( Cui, L; Ma, Z; Wang, G; Wang, Q, 2015) |
| " In addition, our results showed that neither imipramine nor Sanyuansan at any dosage increased spontaneous motor activity." | 1.42 | Antidepressant-like effects of Sanyuansan in the mouse forced swim test, tail suspension test, and chronic mild stress model. ( Gou, XJ; He, G; Lin, B; Peng, C; Yan, S; You, ZL; Zhao, QY, 2015) |
| "Anxiety and depression are common in diabetics." | 1.40 | Anxiety- and depression-like behavior are correlated with leptin and leptin receptor expression in prefrontal cortex of streptozotocin-induced diabetic rats. ( Agilkaya, S; Aksu, I; Ates, M; Baykara, B; Buyuk, E; Cetinkaya, C; Cingoz, S; Dayi, A; Kiray, M; Sisman, AR; Uysal, N, 2014) |
| "Psychiatric disorders have been hypothesized to originate during development, with genetic and environmental factors interacting in the etiology of disease." | 1.40 | Transient downregulation of Dab1 protein levels during development leads to behavioral and structural deficits: relevance for psychiatric disorders. ( Bosch, C; Howell, B; Masachs, N; Muhaisen, A; Pérez-Martínez, J; Soriano, E; Teixeira, CM, 2014) |
| "Here we used a rodent model of PTSD in which rats repeatedly exposed to a stressor display heightened fear learning following auditory Pavlovian fear conditioning." | 1.40 | A ghrelin-growth hormone axis drives stress-induced vulnerability to enhanced fear. ( Burgos-Robles, A; Correia, SS; Goosens, KA; Liu, E; Meyer, RM, 2014) |
| " Chronic administration of resveratrol (80mg/kg, i." | 1.40 | Resveratrol prevents impaired cognition induced by chronic unpredictable mild stress in rats. ( Gu, J; Jiang, H; Liu, D; Wang, J; Wang, X; Wang, Z; Xian, X; Xie, K; Zhang, Q, 2014) |
| "Corticosterone levels were significantly suppressed by ketamine only in the exposed animals." | 1.40 | Immediate ketamine treatment does not prevent posttraumatic stress responses in an animal model for PTSD. ( Cohen, H; Juven-Wetzler, A; Kaplan, Z; Kohen, A; Porat, O; Zohar, J, 2014) |
| "Corticosterone levels were not different in mice subjected to restraint compared to no restraint." | 1.40 | Mechanical allodynia induced by traumatic brain injury is independent of restraint stress. ( Albertson, BK; Daiutolo, BV; Elliott, MB; Macolino, CM, 2014) |
| "Corticosterone levels were used as markers of stress and measured by radioimmunoassay." | 1.40 | Induction of intervertebral disc cell apoptosis and degeneration by chronic unpredictable stress. ( Asadi-Shekaari, M; Esmaeili-Mahani, S; Hoboubati, H; Kermani, HR, 2014) |
| "Depression is a serious mental disorder in the world, but the underlying mechanisms remain unclear and the effective cures are scarce." | 1.40 | Iptakalim confers an antidepressant effect in a chronic mild stress model of depression through regulating neuro-inflammation and neurogenesis. ( Ding, JH; Geng, F; Hu, G; Lu, M; Yang, JZ, 2014) |
| "Post-traumatic stress disorder (PTSD) is a condition which can develop from exposure to a severe traumatic event such as those occurring during wars or natural disasters." | 1.40 | Moderate treadmill exercise rescues anxiety and depression-like behavior as well as memory impairment in a rat model of posttraumatic stress disorder. ( Alkadhi, K; Allam, F; Dao, AT; Li, L; Patki, G; Salim, S; Solanki, N, 2014) |
| "These results reflect hypersomnia by intrusion of NREM sleep during the active period as well as a decrease in sleep/wake continuity." | 1.40 | NREM sleep hypersomnia and reduced sleep/wake continuity in a neuroendocrine mouse model of anxiety/depression based on chronic corticosterone administration. ( Adrien, J; David, DJ; Escourrou, P; Guiard, BP; Guilloux, JP; Hache, G; Le Dantec, Y, 2014) |
| "Treatment with emodin normalized the change of plasma corticosterone level, which demonstrated that emodin could partially restore CUMS-induced HPA axis impairments." | 1.40 | Emodin opposes chronic unpredictable mild stress induced depressive-like behavior in mice by upregulating the levels of hippocampal glucocorticoid receptor and brain-derived neurotrophic factor. ( Fu, Q; Li, M; Li, S; Li, Y; Ma, S; Xue, J, 2014) |
| "Behavioral modifications for the treatment of obesity, including caloric restriction, have notoriously low long-term success rates relative to bariatric weight-loss surgery." | 1.40 | Weight loss by calorie restriction versus bariatric surgery differentially regulates the hypothalamo-pituitary-adrenocortical axis in male rats. ( Benoit, SC; Egan, AE; Grayson, BE; Hakala-Finch, AP; Herman, JP; Kekulawala, M; Laub, H; Ressler, IB; Seeley, RJ; Ulrich-Lai, YM; Woods, SC, 2014) |
| " Additionally, the effects of chronic administration of the tricyclic antidepressant imipramine and the anti-TNF-α pentoxyphylline were investigated." | 1.40 | Lipopolysaccharide repeated challenge followed by chronic mild stress protocol introduces a combined model of depression in rats: reversibility by imipramine and pentoxifylline. ( Abd-Alkhalek, HA; Abdel-tawab, AM; Aboul-Fotouh, S; El Tabbal, M; Elgarf, AS; Farrag, KA; Hammouda, GA; Hassan, AN; Kassim, SK, 2014) |
| "Corticosterone treatment induced longer immobility times in the FST, reflecting depressive-like behaviour." | 1.40 | Long-term corticosterone exposure decreases insulin sensitivity and induces depressive-like behaviour in the C57BL/6NCrl mouse. ( Blokland, A; Cañete, R; Pawluski, JL; Sierksma, AS; Steinbusch, HW; Vaessen, KR; van Donkelaar, EL, 2014) |
| "Honokiol (HNK) is a biphenolic neolignan possessing multiple biological activities including antioxidant, anti-inflammatory, anxiolytic, antidepressant and neuroprotective." | 1.40 | Honokiol abrogates lipopolysaccharide-induced depressive like behavior by impeding neuroinflammation and oxido-nitrosative stress in mice. ( Baruah, CC; Dwivedi, S; Hazarika, NK; Jangra, A; Kumar, P; Lahkar, M; Sulakhiya, K, 2014) |
| "Corticosterone or vehicle was injected twice daily in rats from 8 to 12 weeks of age." | 1.39 | Glucocorticoid-induced hypertension and cardiac injury: effects of mineralocorticoid and glucocorticoid receptor antagonism. ( Hattori, T; Iwase, E; Miyachi, M; Murase, T; Murohara, T; Nagata, K; Ohtake, M; Takahashi, K; Tsuboi, K, 2013) |
| "Corticosterone serum levels were also measured." | 1.39 | Chronic unpredictable mild stress alters an anxiety-related defensive response, Fos immunoreactivity and hippocampal adult neurogenesis. ( Abrão, RO; Britto, LR; Céspedes, IC; da Silva, RC; de Andrade, JS; Diniz, L; Dos Santos, TB; Melo-Thomas, L; Ortolani, D; Spadari-Bratfisch, RC; Viana, MB, 2013) |
| "Tooth loss is a known risk factor of Alzheimer's disease (AD)." | 1.39 | Tooth loss induces memory impairment and neuronal cell loss in APP transgenic mice. ( Akagawa, Y; Jung, CG; Koretake, K; Michikawa, M; Miyamoto, Y; Okada, S; Oue, H, 2013) |
| "Sivelestat is a specific neutrophil elastase inhibitor, which has been developed in Japan in 1991." | 1.39 | Protective effects of sivelestat in a caerulein-induced rat acute pancreatitis model. ( Cao, J; Liu, Q, 2013) |
| "Corticosterone-treated CB1-KO mice showed a lack of weight gain and of increase in hypothalamic and hepatic AMPK activity." | 1.39 | CB1 receptor mediates the effects of glucocorticoids on AMPK activity in the hypothalamus. ( Fekete, C; Füzesi, T; Grossman, AB; Kola, B; Korbonits, M; Scerif, M; Thomas, JD, 2013) |
| "The management for post-traumatic stress disorder (PTSD) involves chronic administration of drugs." | 1.39 | Risperidone ameliorates post-traumatic stress disorder-like symptoms in modified stress re-stress model. ( Garabadu, D; Joy, KP; Krishnamurthy, S, 2013) |
| "Epilepsy is a heterogeneous and chronic neurological condition of undefined etiology in the majority of cases." | 1.39 | Prenatal transport stress, postnatal maternal behavior, and offspring sex differentially affect seizure susceptibility in young rats. ( Currie, RW; Esser, MJ; Galic, MA; Moriyama, C; Mychasiuk, R; Perrot, TS; Pittman, QJ, 2013) |
| "After 72h of REM sleep deprivation, the blood pressure (BP) levels and the QTc interval of the electrocardiogram (ECG) were significantly increased (P<." | 1.39 | Susceptibility to life-threatening ventricular arrhythmias in an animal model of paradoxical sleep deprivation. ( Ghorbani-Shahrbabaki, S; Hajali, V; Joukar, S; Naghsh, N; Sheibani, V, 2013) |
| "Schizophrenia is associated with increased risk for multiple metabolic abnormalities, including altered glucose homeostasis, type-2 diabetes, obesity, and cardiovascular disease." | 1.39 | Priming of metabolic dysfunctions by prenatal immune activation in mice: relevance to schizophrenia. ( Giovanoli, S; Langhans, W; Meyer, U; Pacheco-López, G, 2013) |
| "The suspension system was attached to rat tails in both the HS and sham-HS groups, but the hindlimbs were suspended only in the HS group." | 1.39 | Hindlimb suspension does not influence mechanical sensitivity, epidermal thickness, and peripheral nerve density in the glabrous skin of the rat hind paw. ( Hamaue, Y; Kataoka, H; Nakano, J; Okita, M; Sakamoto, J; Sekino, Y; Tanaka, Y, 2013) |
| "Propranolol is a β-adrenergic antagonist commonly used in the treatment of hypertension or acute anxiety." | 1.39 | Propranolol reduces cognitive deficits, amyloid β levels, tau phosphorylation and insulin resistance in response to chronic corticosterone administration. ( Aguirre, N; Dobarro, M; Orejana, L; Ramírez, MJ, 2013) |
| "Coenzyme Q10 (CoQ10) is an essential cofactor in the mitochondrial electron transport pathway and has a powerful antioxidant capacity." | 1.39 | Coenzyme Q10 displays antidepressant-like activity with reduction of hippocampal oxidative/nitrosative DNA damage in chronically stressed rats. ( Aboul-Fotouh, S, 2013) |
| " It has also been found that the blockade of 5-HT(7) receptors by the selective antagonist SB 269970, lasting for a few days, causes similar changes to those observed after long-term administration of antidepressants." | 1.38 | Stress- and antidepressant treatment-induced modifications of 5-HT₇ receptor functions in the rat brain. ( Bobula, B; Grzegorzewska-Hiczwa, M; Hess, G; Kusek, M; Tokarski, K, 2012) |
| " Experiments showed that administration of extract (25, 50 and 100 mg kg(-1)) could induced analgesia in a dose-response manner in both phases of formalin test." | 1.38 | Effects of Papaver rhoeas (L.) extract on formalin-induced pain and inflammation in mice. ( Delfan, B; Esfandiari, B; Ghahramani, M; Jafari, F; Mojabi, N; Najafi-Abedi, A; Rahmani, B; Ranjbaran, M; Saeed-Abadi, S; Sahraei, H, 2012) |
| "Anxiety and depression are considered as stress-related disorders, which present considerable sex differentiation." | 1.38 | Behavioral sexual dimorphism in models of anxiety and depression due to changes in HPA axis activity. ( Antoniou, K; Dalla, C; Dendi, A; Kokras, N; Mikail, HG; Papadopoulou-Daifoti, Z; Sideris, AC, 2012) |
| "Melancholic depression has typically been associated with HPA hyperactivity, while atypical depression has been linked with HPA hypoactivity." | 1.38 | Lack of elevations in glucocorticoids correlates with dysphoria-like behavior after repeated social defeat. ( Bhatnagar, S; Bowens, N; Heydendael, W; Jacobson, L, 2012) |
| "Fluoxetine or vehicle was administered to the dam during the postpartum period via osmotic minipump implants (Alzet) for 28 days." | 1.38 | Chronic fluoxetine treatment and maternal adversity differentially alter neurobehavioral outcomes in the rat dam. ( Charlier, TD; Crispin, HT; Fillet, M; Houbart, V; Pawluski, JL; Steinbusch, HW; van den Hove, DL, 2012) |
| "In partial sciatic nerve ligation, neuropathic pain model corticosterone increased only in the first days whereas mechanical hypersensitivity remained much longer." | 1.38 | Plasma corticosterone levels in mouse models of pain. ( Benedetti, M; Cadetti, F; dos Santos, P; Kusuda, R; Lucas, G; Merino, R; Ravanelli, MI; Zanon, S, 2012) |
| "Posttraumatic stress disorder (PTSD) is a debilitating disease, which affects 8-10% of the population exposed to traumatic events." | 1.38 | Susceptibility to PTSD-like behavior is mediated by corticotropin-releasing factor receptor type 2 levels in the bed nucleus of the stria terminalis. ( Chen, A; Gil, S; Kuperman, Y; Lebow, M; Neufeld-Cohen, A; Tsoory, M, 2012) |
| "Williams-Beuren syndrome (WBS) is a rare genetic disorder caused by a hemizygous deletion of around 28 genes on the long arm of chromosome 7 (7q11." | 1.38 | Anxious, hypoactive phenotype combined with motor deficits in Gtf2ird1 null mouse model relevant to Williams syndrome. ( Deacon, RM; Flint, J; Karmiloff-Smith, A; Liu, Y; Rawlins, JN; Schneider, T; Skitt, Z; Tassabehji, M, 2012) |
| "Pretreatment with clonidine or yohimbine failed to affect basal plasma corticosterone and ACTH concentrations, but abolished diazepam-induced inhibition of the HPA axis activity." | 1.38 | The involvement of noradrenergic mechanisms in the suppressive effects of diazepam on the hypothalamic-pituitary-adrenal axis activity in female rats. ( Muck-Šeler, D; Pivac, N; Švob Štrac, D, 2012) |
| "Propranolol treatment did not affect the acute or chronic elevation of corticosterone, the decrease in body weight gain, or adrenal hypertrophy observed in animals exposed to stress." | 1.38 | Fear conditioning can contribute to behavioral changes observed in a repeated stress model. ( Camp, RM; Johnson, JD; Kalburgi, SN; Porterfield, VM; Remus, JL, 2012) |
| "In rodents, sleep deprivation (SD) negatively affects consolidation of hippocampus-dependent memories." | 1.38 | Post-exposure sleep deprivation facilitates correctly timed interactions between glucocorticoid and adrenergic systems, which attenuate traumatic stress responses. ( Cohen, H; Cohen, S; Kaplan, Z; Kozlovsky, N; Matar, MA; Zohar, J, 2012) |
| "Chronic pain and depression are two complex states with sensory/somatic and emotional components, and they may mutually exacerbate one another in conditions of comorbidity, leading to a poorer prognosis." | 1.38 | Depressive-like states heighten the aversion to painful stimuli in a rat model of comorbid chronic pain and depression. ( Berrocoso, E; Bravo, L; Leza, JC; Mico, JA; Pérez-Nievas, B; Rey-Brea, R, 2012) |
| "Thus, CMS and sleep deprivation, when given alone, have distinct region-specific effects." | 1.38 | Post-transcriptional effects and interactions between chronic mild stress and acute sleep deprivation: regulation of translation factor and cytoplasmic polyadenylation element-binding protein phosphorylation. ( Bramham, CR; Dagestad, G; Grønli, J; Milde, AM; Murison, R, 2012) |
| "Obesity is a disease that has become a serious public health issue worldwide, and chronic stressors, which are a problem for modern society, cause neuroendocrine changes with alterations in food intake." | 1.38 | Cafeteria diet-induced obesity plus chronic stress alter serum leptin levels. ( Caumo, W; Cioato, SG; Macedo, IC; Medeiros, LF; Oliveira, C; Oliveira, CM; Rozisky, JR; Santos, VS; Scarabelot, VL; Silva, FR; Souza, A; Torres, IL, 2012) |
| "Depression is a life-threatening psychiatric disorder characterized with a long-term hypercortisolemia in depressed patients." | 1.38 | Synaptic plasticity, but not hippocampal neurogenesis, mediated the counteractive effect of wolfberry on depression in rats(1). ( Chang, RC; Lau, BW; Lee, TM; Ma, H; So, KF; Yau, SY; Zhang, E, 2012) |
| "Psoriasis is a chronic recurrent inflammatory skin disorder with multifactorial etiology, including genetic background, environmental factors, and immune system disturbances with a strong cytokine component." | 1.38 | Sleep loss and cytokines levels in an experimental model of psoriasis. ( Andersen, ML; Araújo, MS; Hirotsu, C; Rydlewski, M; Tufik, S, 2012) |
| "Nicotine solutions were then adulterated with bitter-tasting quinine to test flexibility." | 1.37 | Long-term development of excessive and inflexible nicotine taking by rats, effects of a novel treatment approach. ( Galli, G; Wolffgramm, J, 2011) |
| "Depression is a major psychiatric disorder affecting nearly 21% of the world population and imposes a substantial health burden on society." | 1.37 | Protective effects of flavonoid extract from Apocynum venetum leaves against corticosterone-induced neurotoxicity in PC12 cells. ( Liu, C; Ma, F; Pan, F; Shi, D; Zhang, Y; Zheng, M, 2011) |
| "Icariin is a major constituent of flavonoids isolated from the herb Epimedium." | 1.37 | Icariin attenuates social defeat-induced down-regulation of glucocorticoid receptor in mice. ( Dong, J; Du, J; Le, J; Liu, B; Wu, J; Xu, C; Xu, Y, 2011) |
| " Chronic administration of H." | 1.37 | St. John's wort may relieve negative effects of stress on spatial working memory by changing synaptic plasticity. ( Braszko, JJ; Holownia, A; Trofimiuk, E, 2011) |
| "Anticipatory nausea is produced by pairing a novel distinctive context with the nausea-inducing effects of a toxin, such as LiCl." | 1.37 | Acute corticosterone increases conditioned spontaneous orofacial behaviors but fails to influence dose related LiCl-induced conditioned "gaping" responses in a rodent model of anticipatory nausea. ( Biagi, E; Chan, MY; Cloutier, CJ; Cross-Mellor, SK; Kavaliers, M; Ossenkopp, KP, 2011) |
| "Major depression is an independent risk factor for the development of cardiovascular disease." | 1.37 | Altered aortic vascular reactivity in the unpredictable chronic mild stress model of depression in mice: UCMS causes relaxation impairment to ACh. ( Belzung, C; Camus, V; d'Audiffret, A; Freslon, JL; Frisbee, J; Isingrini, E; O'Donnell, J; Surget, A, 2011) |
| "A standardization of sleep deprivation procedures involving gentle handling will be important for unequivocally specifying how acute sleep loss affects brain function." | 1.37 | Do mice habituate to "gentle handling?" A comparison of resting behavior, corticosterone levels and synaptic function in handled and undisturbed C57BL/6J mice. ( Fan, J; Kopp, C; Longordo, F; Lüthi, A; Steimer, T, 2011) |
| "It is unclear, however, how genetic predisposition to a behavioural disorder, such as attention-deficit/hyperactivity disorder (ADHD), modifies the long-term effects of early life trauma." | 1.37 | Effects of early life trauma are dependent on genetic predisposition: a rat study. ( Howells, FM; Russell, VA; Sterley, TL, 2011) |
| "Corticosterone treatment resulted in a dramatic decrease of polyamine contents at most of the time points investigated when compared with those in control rats." | 1.37 | The influence of corticosterone on antizyme gene expression in early regenerating rat liver. ( Dong, JF; Li, JK; Ma, JM; Ning, QJ; Yang, H, 2011) |
| "Daidzein treatment significantly decreased (p<0." | 1.37 | Daidzein effects on ACTH cells: immunohistomorphometric and hormonal study in an animal model of the andropause. ( Ajdzanovic, VZ; Filipoviç, BR; Milosevic, VLj; Sosic-Jurjevic, BT; Trifunovic, SL, 2011) |
| "In this acute porphyria model, gluconeogenic and glycogenolytic blockages caused by PEPCK and GP depressed activities, respectively, would be mainly a consequence of the negative regulatory action of insulin on these enzymes." | 1.37 | How porphyrinogenic drugs modeling acute porphyria impair the hormonal status that regulates glucose metabolism. Their relevance in the onset of this disease. ( D'Andrea, F; Fornes, D; Matkovic, LB; Mazzetti, MB; San Martín de Viale, LC, 2011) |
| "Propranolol is a non-selective β adrenergic receptor blocker which antagonises the anti-inflammatory effect of non-steroidal anti-inflammatory drugs via the β1 and β2 adrenergic receptors." | 1.37 | Effects of epinephrine and cortisol on the analgesic activity of metyrosine in rats. ( Akcay, F; Albayrak, Y; Karatay, S; Polat, B; Saglam, MB; Suleyman, H; Uslu, T; Yildirim, K, 2011) |
| "The nicotine-induced increase in SCS level was suppressed by DHβE, but not MLA." | 1.37 | Pharmacological relationship between nicotinic and opioid systems in analgesia and corticosterone elevation. ( Kiguchi, N; Kishioka, S; Kobayashi, Y; Maeda, T; Ueno, K; Yamamoto, A; Yamamoto, C, 2011) |
| "Corticosterone levels were not different between wild-type and MOP-KO mice before stress exposure." | 1.36 | Reduced emotional and corticosterone responses to stress in mu-opioid receptor knockout mice. ( Ide, S; Ikeda, K; Ishihara, K; Minami, M; Sora, I; Uhl, GR, 2010) |
| "The treatment with imipramine reversed all the parameters described above." | 1.36 | Depressive-like parameters in sepsis survivor rats. ( Barichello, T; Cassol, OJ; Comim, CM; Constantino, LC; Constantino, LS; Dal-Pizzol, F; Kapczinski, F; Petronilho, F; Quevedo, J; Stertz, L, 2010) |
| "Post-traumatic stress disorder (PTSD) is unique among psychiatric disorders since there is an explicit requirement for the presence of a well-defined precipitating environmental event." | 1.36 | DNA methylation in vulnerability to post-traumatic stress in rats: evidence for the role of the post-synaptic density protein Dlgap2. ( Ben-Shachar, D; Chertkow-Deutsher, Y; Cohen, H; Klein, E, 2010) |
| "Hyperammonemia is a main contributor to the neurological alterations in hepatic encephalopathy." | 1.36 | Chronic hyperammonemia alters the circadian rhythms of corticosteroid hormone levels and of motor activity in rats. ( Ahabrach, H; Ayad, A; El Mlili, N; Errami, M; Felipo, V; Llansola, M; Piedrafita, B, 2010) |
| "Activity-based anorexia is a paradigm that induces increased physical activity, reduced food intake, and heightened activity of the hypothalamic-pituitary-adrenal axis in adult rats." | 1.36 | Adolescent activity-based anorexia increases anxiety-like behavior in adulthood. ( Hargrave, SL; Kinzig, KP, 2010) |
| "Corticosterone release was higher in crowded rats throughout day 15." | 1.36 | Chronological assessment of mast cell-mediated gut dysfunction and mucosal inflammation in a rat model of chronic psychosocial stress. ( Alonso, C; Azpiroz, F; González, A; Guilà, M; Guilarte, M; Lobo, B; Martínez, C; Pigrau, M; Ramos, L; Santos, J; Saperas, E; Vicario, M; Yang, P, 2010) |
| "Because sleep deprivation also induces stress, we here determined the contribution of the corticosterone component of the stress response to the electrophysiological and molecular markers of sleep need in mice." | 1.36 | Separating the contribution of glucocorticoids and wakefulness to the molecular and electrophysiological correlates of sleep homeostasis. ( Curie, T; Dorsaz, S; Franken, P; Gip, P; Hagiwara, G; Heller, HC; Hernandez, SA; Mongrain, V; Pradervand, S, 2010) |
| "Autism is a neurodevelopmental disorder characterized by abnormal reciprocal social interactions, communication deficits, and repetitive behaviors with restricted interests." | 1.36 | Low stress reactivity and neuroendocrine factors in the BTBR T+tf/J mouse model of autism. ( Bell, DB; Crawley, JN; Katz, AM; Koenig, JI; Silverman, JL; Turner, SM; Yang, M, 2010) |
| "Here we examined the effects of sleep deprivation on memory consolidation for contextual fear in rats when the task was performed at different times of the day, particularly, at the beginning of the resting phase or right before the onset of the active phase." | 1.36 | A time for learning and a time for sleep: the effect of sleep deprivation on contextual fear conditioning at different times of the day. ( Hagewoud, R; Havekes, R; Heeringa, AN; Koolhaas, JM; Meerlo, P; Whitcomb, SN, 2010) |
| "five hours of sleep deprivation after each daily training session did not affect performance during training." | 1.36 | Coping with sleep deprivation: shifts in regional brain activity and learning strategy. ( Hagewoud, R; Havekes, R; Hogenelst, K; Meerlo, P; Novati, A; Tiba, PA; Van der Zee, EA; Weinreder, P, 2010) |
| "Some of the symptoms of PTSD include persistent anxiety, exaggerated startle, cognitive impairments and increased sensitivity to yohimbine, an alpha(2)-adrenergic receptor antagonist." | 1.35 | Acute episodes of predator exposure in conjunction with chronic social instability as an animal model of post-traumatic stress disorder. ( Conrad, CD; Diamond, DM; Fleshner, M; Zoladz, PR, 2008) |
| "Colitis was induced in C57BL/6 female mice by exposure to 3% DSS (5 days)." | 1.35 | Psychological stress reactivates dextran sulfate sodium-induced chronic colitis in mice. ( Engström, K; Jägervall, A; Martinez, V; Melgar, S, 2008) |
| " This work provides novel observations which indicate that agomelatine blocks the adverse effects of stress on hippocampus-dependent memory and activates molecular mechanisms of memory storage in response to a learning experience." | 1.35 | The antidepressant agomelatine blocks the adverse effects of stress on memory and enables spatial learning to rapidly increase neural cell adhesion molecule (NCAM) expression in the hippocampus of rats. ( Campbell, AM; Conboy, L; Diamond, DM; Gabriel, C; Mocaer, E; Park, CR; Sandi, C; Tanrikut, C; Zoladz, PR, 2009) |
| "Both nimodipine treatments prevented the memory deficits when these were measured between 1 and 2 months after alcohol withdrawal." | 1.35 | Nimodipine prior to alcohol withdrawal prevents memory deficits during the abstinence phase. ( Brooks, SP; Croft, AP; Little, HJ; Norman, G; Shaw, SG, 2008) |
| "Alprazolam was associated with a significant attenuation of the HPA-response, suggesting a possible link between initial HPA-axis response disruption and the subsequent unfavorable outcomes." | 1.35 | Alprazolam treatment immediately after stress exposure interferes with the normal HPA-stress response and increases vulnerability to subsequent stress in an animal model of PTSD. ( Cohen, H; Kaplan, Z; Matar, MA; Zohar, J, 2009) |
| "5-hydroxyindoleacetic acid (5HIAA) was also found to be increased in hypothalamus by 74% (P<0." | 1.35 | St. John's Wort modulates brain regional serotonin metabolism in swim stressed rats. ( Ara, I; Bano, S, 2009) |
| "Low nephron endowment secondary to intrauterine growth restriction (IUGR) results in compensatory hypertrophy of the remaining glomeruli, which in turn is associated with hypertension." | 1.35 | Uteroplacental insufficiency affects kidney VEGF expression in a model of IUGR with compensatory glomerular hypertrophy and hypertension. ( Bares, AL; Baserga, M; Callaway, CW; Hale, MA; Lane, PH; Lane, RH; McKnight, RA, 2009) |
| " It is hypothesized that once corticosterone reaches the site of inflammation, the enzymes 11beta-hydroxysteroid dehydrogenases (11betaHSDs) can influence bioavailability by interconverting corticosterone and the inert metabolite 11-dehydrocorticosterone." | 1.35 | 11beta-hydroxysteroid dehydrogenases are regulated during the pulmonary granulomatous response to the mycobacterial glycolipid trehalose-6,6'-dimycolate. ( Abbott, AN; Actor, JK; Guidry, TV; Hunter, RL; Kling, MA; Thomas, AM; Welsh, KJ, 2009) |
| "Melatonin is a hormone primarily synthesized by the pineal gland and has been shown to govern seasonal and circadian rhythms, as well as the immune system, certain behaviours, and responses to stress." | 1.35 | Antidepressant-like effects of melatonin in the mouse chronic mild stress model. ( Caumo, W; Detanico, BC; Elisabetsky, E; Freitas, JJ; Hidalgo, MP; Lhullier, FL; Piato, AL, 2009) |
| "Body weight was increased by insulin, decreased by high corticosterone, and unaffected by diet." | 1.35 | Disengaging insulin from corticosterone: roles of each on energy intake and disposition. ( Akana, SF; Dallman, MF; Ginsberg, AB; Horneman, HF; Pecoraro, NC; Warne, JP, 2009) |
| "Depression is frequently reported in epilepsy patients; however, mechanisms of co-morbidity between epilepsy and depression are poorly understood." | 1.35 | Elevated plasma corticosterone level and depressive behavior in experimental temporal lobe epilepsy. ( Bragin, A; Kwon, YS; Mazarati, AM; Pineda, E; Sankar, R; Shin, D; Taylor, AN; Tio, D, 2009) |
| " In this context, the present study was aimed to evaluate behavioral and physiological effects of acute and chronic administration of ketamine, a NMDA receptor antagonist, in rats exposed to chronic mild stress (CMS)." | 1.35 | Ketamine treatment reverses behavioral and physiological alterations induced by chronic mild stress in rats. ( Comim, CM; Garcia, LS; Gavioli, EC; Kapczinski, F; Quevedo, J; Réus, GZ; Stertz, L; Valvassori, SS, 2009) |
| "Corticosterone (CORT)-treated rats have emerged as a pharmacological model of depression-like behaviors." | 1.35 | Morphological reorganization after repeated corticosterone administration in the hippocampus, nucleus accumbens and amygdala in the rat. ( Dumont, Y; Flores, G; Morales-Medina, JC; Quirion, R; Sanchez, F, 2009) |
| "Pulmonary inflammation was not reduced among allergic stressed mice in spite of elevated glucocorticoids." | 1.35 | Acute stress affects the physiology and behavior of allergic mice. ( Hulbert, LE; Krebs, N; McGlone, JJ; Shome, GP; Sutherland, MA; Wachtel, M, 2009) |
| "Rosiglitazone treatment (6 or 12 mg/kg, orally) significantly reduced plasma corticosterone levels in rats." | 1.35 | Antidepressant-like effects of rosiglitazone, a PPARγ agonist, in the rat forced swim and mouse tail suspension tests. ( Al-Rasheed, NM; Eissa Ahmed, AA, 2009) |
| "Obesity is an increasing socio-economic health problem." | 1.35 | Diet-induced obesity alters behavior as well as serum levels of corticosterone in F344 rats. ( Behrendt, P; Bode, FJ; Brabant, G; Buchenauer, T; Horn, R; Nave, H; Stephan, M, 2009) |
| "Corticosterone levels were unchanged by alcohol consumption, but they were decreased by withdrawal in females." | 1.35 | Sexually dimorphic response of the hypothalamo-pituitary-adrenal axis to chronic alcohol consumption and withdrawal. ( Madeira, MD; Santos-Marques, MJ; Silva, SM, 2009) |
| "A novel degenerative disc disease model and sustained delivery method for corticosteroid in male Sprague-Dawley albino rats." | 1.35 | A preliminary report on the effects of sustained administration of corticosteroid on traumatized disc using the adult male rat model. ( Benghuzzi, HA; Fosnaugh, AW; Franklin, LN; Ragab, AA; Tucci, MA; Wingerter, SA; Woodall, JW, 2009) |
| "PCAF KO animals showed short-term memory deficits at 2 months of age, measured using spontaneous alternation, object recognition, or acquisition of a daily changing platform position in the water maze." | 1.35 | Altered memory capacities and response to stress in p300/CBP-associated factor (PCAF) histone acetylase knockout mice. ( Célérier, A; Copois, V; Duclot, F; Givalois, L; Gongora, C; Jacquet, C; Maurice, T; Mechti, N; Meffre, J; Meunier, J; Naert, G; Ozato, K, 2008) |
| "Few animal models of PTSD have taken gender differences into account and have typically used male subjects." | 1.35 | Gender-related qualitative differences in baseline and post-stress anxiety responses are not reflected in the incidence of criterion-based PTSD-like behaviour patterns. ( Cohen, H; Kaplan, Z; Kozlovsky, N; Matar, MA; Mazor, A; Zohar, J, 2009) |
| "Body weights were lower in the IS7-13 group than in the control group from P10 to P50, although body weight gain in the MD7-13 group was only transiently affected." | 1.35 | Repeated immobilization stress in the early postnatal period increases stress response in adult rats. ( Yawaka, Y; Yoshihara, T, 2008) |
| " The latter effect could be mimicked in C57BL/6N mice by acute, subchronic, and chronic administration of the selective CB1 antagonist SR141716." | 1.35 | Antidepressant-like behavioral effects of impaired cannabinoid receptor type 1 signaling coincide with exaggerated corticosterone secretion in mice. ( Holsboer, F; Lutz, B; Marsicano, G; Nestler, EJ; Steiner, MA; Wotjak, CT, 2008) |
| "Obstructive sleep apnoea (OSA) and type 2 diabetes frequently co-exist and potentially interact haemodynamically and metabolically." | 1.35 | Intermittent hypoxia reverses the diurnal glucose rhythm and causes pancreatic beta-cell replication in mice. ( Alonso, LC; Garcia-Ocana, A; Minoguchi, K; O'Doherty, RM; O'Donnell, CP; Romano, LC; Rosa, TC; Yokoe, T, 2008) |
| "Using a mouse model of neonatal respiratory distress syndrome (RDS), we demonstrate a central role for macrophage migration inhibitory factor (MIF) in lung maturation at the developmental stage when human neonates are most susceptible to RDS." | 1.35 | A role for macrophage migration inhibitory factor in the neonatal respiratory distress syndrome. ( Aghai, ZH; Baugh, JA; Bazzy-Asaad, A; Bhandari, V; Bucala, RJ; Donnelly, SC; Dzuira, JD; Fan, J; Kettunen, M; Kevill, KA; Leng, L; McDonald, CL; Mizue, Y; O'Connor, CL; Reyes-Mugica, M, 2008) |
| " Daily administration of onion powder at a dosage of 50 mg/kg of body weight/day for 14 days significantly reduced the immobility time in FST without changing the motor dysfunction, indicating that the daily consumption of onion exerted antidepressant-like activity." | 1.35 | Antidepressant-like effect of onion (Allium cepa L.) powder in a rat behavioral model of depression. ( Kawai, Y; Sakakibara, H; Terao, J; Yoshino, S, 2008) |
| "The model of dehydration-induced anorexia (DIA) leads to decreased voluntary food intake but peptide expression in the arcuate is similar to forced-food restriction (FFR), where animals remain hungered." | 1.35 | Differential response of TRHergic neurons of the hypothalamic paraventricular nucleus (PVN) in female animals submitted to food-restriction or dehydration-induced anorexia and cold exposure. ( de Gortari, P; Jaimes-Hoy, L; Joseph-Bravo, P, 2008) |
| " In the present study, we established a model of hypoactivated HPA axis in rat through chronic administration of corticosterone (40mg/kg, s." | 1.35 | Effects of treadmill exercise on hypoactivity of the hypothalamo-pituitary-adrenal axis induced by chronic administration of corticosterone in rats. ( Ann, ES; Jung, WR; Kim, HG; Kim, KL; Lim, EY; Shin, MK, 2008) |
| " Despite the differences in somatic signs, wild-type and CRF(2)-/- mice displayed similar plasma corticosterone responses to opiate dosing and withdrawal, indicating a marginal role for the hypothalamus-pituitary-adrenal axis in the CRF(2) receptor mediation of opiate withdrawal." | 1.35 | Disruption of the CRF(2) receptor pathway decreases the somatic expression of opiate withdrawal. ( Contarino, A; Ghozland, S; Ingallinesi, M; Koob, GF; Papaleo, F; Roberts, AJ, 2008) |
| "ACTH-induced-hypertension is commonly employed as a model of stress-related hypertension, and despite extensive investigation, the mechanisms underlying elevated blood pressure (BP) are not well understood." | 1.35 | ACTH-induced hypertension is dependent on the ouabain-binding site of the alpha2-Na+-K+-ATPase subunit. ( Dostanic-Larson, I; Lasko, V; Lingrel, JB; Loreaux, EL; Lorenz, JN; Paul, RJ; Schnetzer, JR, 2008) |
| "The pravastatin-treated mice had delayed onset of CIA compared with the controls." | 1.34 | Effects of pravastatin in murine collagen-induced arthritis. ( Funauchi, M; Ikoma, S; Kinoshita, K; Nozaki, Y; Sugiyama, M; Yamagata, T, 2007) |
| "Buprenorphine (0." | 1.34 | Buprenorphine ameliorates the effect of surgery on hypothalamus-pituitary-adrenal axis, natural killer cell activity and metastatic colonization in rats in comparison with morphine or fentanyl treatment. ( Franchi, S; Panerai, AE; Sacerdote, P, 2007) |
| "The findings support a diathesis-stress hypothesis in which genetically seizure susceptible El mice exhibit a multifaceted hyperreactivity to noxious environmental stimuli." | 1.34 | Neural, endocrine and electroencephalographic hyperreactivity to human contact: a diathesis-stress model of seizure susceptibility in El mice. ( Forcelli, PA; Heinrichs, SC; Orefice, LL, 2007) |
| "Imipramine treatment offset all the behavioral and neurochemical stress-induced modifications." | 1.34 | Hypothalamus-pituitary-adrenal modifications consequent to chronic stress exposure in an experimental model of depression in rats. ( Cassanelli, A; Danielli, B; De Montis, MG; Raone, A; Rauggi, R; Scheggi, S, 2007) |
| "In conclusion, the cuprizone model of demyelination and remyelination does not appear to influence the systemic nor central IL-1, IL-6, and TNF responses to acute nor repeated LPS." | 1.34 | Effects of acute and repeated exposure to lipopolysaccharide on cytokine and corticosterone production during remyelination. ( Kusnecov, AW; Urbach-Ross, D, 2007) |
| "Post-traumatic stress disorder (PTSD) is a stress-related mental disorder caused by traumatic experience, and presents with characteristic symptoms, such as intrusive memories, a state of hyperarousal, and avoidance, that endure for years." | 1.34 | Glucocorticoid receptor activation is involved in producing abnormal phenotypes of single-prolonged stress rats: a putative post-traumatic stress disorder model. ( Harada, K; Hoshino, A; Kato, K; Kato, N; Kohda, K; Matsuoka, N; Morinobu, S; Motohashi, J; Yamaji, T, 2007) |
| "Corticosterone levels were determined by radioimmunoassay." | 1.34 | Nicotine-induced prenatal overexposure to maternal glucocorticoid and intrauterine growth retardation in rat. ( Chen, M; Feng, YH; Liao, ZX; Pan, XL; Wang, H; Wang, T, 2007) |
| "Post-traumatic stress disorder (PTSD) affects a vulnerable sub-population of individuals exposed to a traumatic event." | 1.33 | Long-term behavioural alterations in female rats after a single intense footshock followed by situational reminders. ( Darnaudéry, M; Ducrocq, F; Louvart, H; Maccari, S; Thomas, P, 2005) |
| " E(2), 10 mug, compared to vehicle or 50 mug, reduced anxiety and depressive behavior of sham and adrenalectomized rats administered the low dosage of corticosterone, but not vehicle or the high dosage of corticosterone, suggesting that there may be an optimal level of corticosterone necessary for E(2) to exert these effects." | 1.33 | Antianxiety and antidepressive behavior produced by physiological estradiol regimen may be modulated by hypothalamic-pituitary-adrenal axis activity. ( Frye, CA; Walf, AA, 2005) |
| "Electroconvulsive seizure (ECS)-treatment, an animal model for the antidepressant treatment electroconvulsive therapy, can enhance proliferation of glial cells." | 1.33 | Corticosterone-induced inhibition of gliogenesis in rat hippocampus is counteracted by electroconvulsive seizures. ( Ekstrand, J; Hellsten, J; Lindgren, H; Tingström, A; Wennström, M, 2006) |
| "Defective CRR to hypoglycemia is a component of the clinical syndrome hypoglycemia-associated autonomic failure (HAAF)." | 1.33 | Feeding and neuroendocrine responses after recurrent insulin-induced hypoglycemia. ( Daumen, W; Figlewicz, DP; Levin, BE; Sanders, NM; Taborsky, GJ; Wilkinson, CW, 2006) |
| "Gastric ulcer is a source of visceral pain." | 1.33 | Somatic pain sensitivity during formation and healing of acetic acid-induced gastric ulcers in conscious rats. ( Bogdanov, A; Filaretova, L; Yarushkina, N, 2006) |
| " Chronic administration of the "equivalent" to the stress dose of exogenous corticosterone (5 mg kg(-1) daily for 21 days) also impaired recall of PAB, and this effect was also reversed by Hypericum perforatum." | 1.33 | St john's wort (Hypericum perforatum) counteracts deleterious effects of the chronic restraint stress on recall in rats. ( Braszko, JJ; Trofimiuk, E; Walesiuk, A, 2006) |
| "Since depression is a multifaceted disorder, and a number of symptoms may be present, including circadian rhythm disturbances, we attempted to find the chronobiological abnormalities in CMS rats." | 1.33 | Chronobiological disturbances with hyperthermia and hypercortisolism induced by chronic mild stress in rats. ( Higuchi, S; Morikawa, T; Ohdo, S; To, H; Ushijima, K, 2006) |
| "Oxytocin (OT) has been implicated in the expression of social behavior, stress responses, and may provide a mechanism by which social experience influences atherogenesis in WHHL rabbits." | 1.33 | Social experience influences hypothalamic oxytocin in the WHHL rabbit. ( Gonzales, JA; Levine, JE; Llabre, MM; McCabe, PM; Mendez, AJ; Paredes, J; Schneiderman, N; Szeto, A; Zaias, J, 2006) |
| "Treatment with corticosterone at E10, E12, E14 and E16 produced the same cognitive outcomes as hypoxia at the same prehatch ages." | 1.33 | The role of corticosterone in prehatch-induced memory deficits in chicks. ( Gibbs, ME; Jenkin, G; Miller, SL; Rodricks, CL, 2006) |
| "Anxiety and depression are currently classified as separate clinical syndromes despite considerable similarities in their symptoms, pathophysiological substrates and response to treatment interventions." | 1.33 | Modeling the anxiety-depression continuum hypothesis in domestic fowl chicks. ( Acevedo, EO; Cartwright, CM; Feltenstein, MW; Sufka, KJ; Warnick, JE; Webb, HE, 2006) |
| "The final procedure, sleep deprivation, involves passive denial of the opportunity to sleep." | 1.33 | Application of experimental stressors in laboratory rodents. ( Heinrichs, SC; Koob, GF, 2006) |
| "Corticosterone treatment decreased [3H] 8-hydroxy-2-(di-n-propylamino)tetralin binding to the 5-hydroxytryptamine1A receptor in the cortex but not in the hippocampus." | 1.32 | Implantation of a slow release corticosterone pellet induces long-term alterations in serotonergic neurochemistry in the rat brain. ( Bush, VL; Fone, KC; Marsden, CA; Middlemiss, DN, 2003) |
| "Corticosterone levels were similar in both groups." | 1.32 | The adrenal cortex in experimental congenital diaphragmatic hernia. ( Diez-Pardo, JA; Gonzalez-Reyes, S; Martínez, I; Martínez, L; Rodriguez, JI; Rodriguez-Matas, MJ; Tovar, JA, 2003) |
| "Depression is a multifactorial illness and genetic factors play a role in its etiology." | 1.32 | Behavioral, neurochemical, and electrophysiological characterization of a genetic mouse model of depression. ( Adrien, J; Bouali, S; Costentin, J; El Yacoubi, M; Hamon, M; Leroux-Nicollet, I; Naudon, L; Popa, D; Vaugeois, JM, 2003) |
| "Fluoxetine treatment also reversed the deficit in escape latency observed in animals exposed to IS." | 1.32 | Cell proliferation in adult hippocampus is decreased by inescapable stress: reversal by fluoxetine treatment. ( Duman, RS; Malberg, JE, 2003) |
| "and aims: Primary sclerosing cholangitis is a Th1 cytokine driven disease with a poor clinical responsiveness to glucocorticoid therapy." | 1.32 | Glucocorticoid receptors are downregulated in hepatic T lymphocytes in rats with experimental cholangitis. ( Le, T; Swain, MG; Tjandra, K, 2003) |
| "Corticosterone levels were elevated in CMS-treated animals relative to the singly housed control groups, but exposure to a subsequent stressor was not influenced by the stress history." | 1.32 | Evaluation of the effects of chronic mild stressors on hedonic and physiological responses: sex and strain compared. ( Baker, SL; Barbagallo, LS; Bielajew, C; Kentner, AC; Konkle, AT; Merali, Z, 2003) |
| "Pre-treatment with corticosterone (0." | 1.32 | (-)-nicotine ameliorates corticosterone's potentiation of N-methyl-d-aspartate receptor-mediated cornu ammonis 1 toxicity. ( Harris, BR; Littleton, JM; Mulholland, PJ; Prendergast, MA; Self, RL, 2004) |
| "Corticosterone serum levels were elevated in both sexes." | 1.32 | Sex differences in behavioral, neurochemical and neuroendocrine effects induced by the forced swim test in rats. ( Antoniou, K; Dalla, C; Drossopoulou, G; Kitraki, E; Papadopoulou-Daifoti, Z; Papalexi, E; Papathanasiou, G, 2004) |
| "M phi, PGE(2) and IL-6 production in Trauma+Intact mice was significantly increased compared with Control+Intact mice." | 1.32 | Neuroendocrine responses mediate macrophage function after trauma. ( Daly, JM; Duff, M; Freeman, TA; Maddali, S; Smyth, GP; Stapleton, PP; Yan, Z, 2004) |
| "Pretreatment with metyrapone (100 m a g , intraperitoneal)1 h before inescapable stress (40 2mA tail shocks delivered over a 1-h period) (IS)blocked the acute plasma corticosterone response to IS." | 1.31 | Pharmacological suppression of corticosterone secretion in response to a physical stressor does not prevent the delayed persistent increase in circulating basal corticosterone concentration. ( Beck, KD; Beldowicz, D; Brennan, FX; Moldow, RL; Ottenweller, JE; Servatius, RJ; Zhug, G, 2001) |
| "Mifepristone pretreatment significantly reduced the apoptosis and caspase-3 activity after burn injury, whereas blocking FasL activity had only minimal effects." | 1.31 | Glucocorticoid-induced, caspase-dependent organ apoptosis early after burn injury. ( Clare-Salzler, M; Copeland, EM; Edwards, CK; Fukuzuka, K; Moldawer, LL; Mozingo, DW, 2000) |
| "In rats with acute hepatic failure, the hepatic P-glycoprotein concentration increased 1." | 1.31 | Expression and function of P-glycoprotein in rats with carbon tetrachloride-induced acute hepatic failure. ( Huang, ZH; Murakami, T; Nagai, J; Okochi, A; Takano, M; Yumoyo, R, 2001) |
| "Due to the complexity of PTSD, animal models have been designed and advanced to address the role of psychosocial stressors in the etiology; however, the apparent role of genetics in susceptibility to PTSD-like behaviors in animals remains unexplored." | 1.31 | Genetic predisposition and the development of posttraumatic stress disorder in an animal model. ( Abend, S; Edwards, E; King, JA, 2001) |
| "Other childhood seizures are also responsive to ACTH." | 1.31 | The effects of ACTH and adrenocorticosteroids on seizure susceptibility in 15-day-old male rats. ( Burnham, WM; Edwards, HE; Vimal, S, 2002) |
| "Oral hormone substitution for the treatment of Addison's disease inadequately replaces the physiologic circadian secretion of corticosteroids." | 1.31 | Transplantation of adrenal tissue fragments in a murine model: functional capacities of syngeneic and allogeneic grafts. ( Ellerkamp, V; Hoffmann, MW; Klebs, SH; Klempnauer, J; Musholt, PB; Musholt, TJ, 2002) |
| "The mice then underwent soft-tissue trauma (laparotomy) and hemorrhagic shock (blood pressure 35+/-5 mm Hg for 90 minutes) followed by adequate fluid resuscitation (shed blood and lactated Ringer's solution) or sham operation." | 1.30 | Testosterone and/or low estradiol: normally required but harmful immunologically for males after trauma-hemorrhage. ( Angele, MK; Ayala, A; Bland, KI; Chaudry, IH; Cioffi, WG; Monfils, BA, 1998) |
| "High corticosterone levels were detected during stages of acute paralysis, whereas a decrease to normal levels was noted during each recovery phase." | 1.29 | Immunoregulation and drug treatment in chronic relapsing experimental allergic encephalomyelitis in the Lewis rat. ( Borel, JF; Chabannes, D; Kovarik, J, 1995) |
| "CRH-induced seizure duration (88." | 1.29 | ACTH does not control neonatal seizures induced by administration of exogenous corticotropin-releasing hormone. ( Baram, TZ; Schultz, L, 1995) |
| "Corticosterone levels were lower in GK rat plasma than in normal Wistar rat plasma." | 1.29 | Diabetic GK rat plasma but not normal Wistar rat plasma induces insulin-stimulated DNA synthesis in primary cultured smooth muscle cells in GK rat aorta. ( Kimura, I; Kimura, M; Naitoh, T; Nakano, Y; Okabe, M, 1994) |
| "Moderate sensitivity to adjuvant arthritis was found in a selected, stress-resistant line of the Wistar rat, whereas no arthritis was found in a stress-susceptible Wistar line." | 1.29 | Susceptibility to adjuvant arthritis: relative importance of adrenal activity and bacterial flora. ( Cools, AR; Hermus, AR; Sweep, CG; van de Langerijt, AG; van den Berg, WB; van Lent, PL, 1994) |
| "Posttraumatic stress disorder (PTSD) may occur in humans exposed chronically to stressors or after a single exposure to a traumatic event." | 1.29 | Delayed startle sensitization distinguishes rats exposed to one or three stress sessions: further evidence toward an animal model of PTSD. ( Natelson, BH; Ottenweller, JE; Servatius, RJ, 1995) |
| " Because teratogenic effects follow a toxicologic dose-response curve with a no-effect dose, frequently counselors can refute a causal relationship because the dose was far below the no-observable-effect dose." | 1.29 | Is there a no-effect dose for corticosteroid-induced cleft palate? The contribution of endogenous corticosterone to the incidence of cleft palate in mice. ( Beckman, DA; Brent, RL; Buck, SJ; Fawcett, LB, 1996) |
| "Hydrazine sulfate pretreatment also protects D-galactosamine-sensitized mice against the lethal effects of injected tumor necrosis factor/cachectin." | 1.28 | Hydrazine sulfate protects D-galactosamine-sensitized mice against endotoxin and tumor necrosis factor/cachectin lethality: evidence of a role for the pituitary. ( Christoffersen, CA; Johnson, DC; Morrison, DC; Silverstein, R; Turley, BR, 1991) |
| "Body weight was significantly (P less than ." | 1.28 | Ascites in growing broilers: a research model. ( Elissalde, MH; Harvey, RB; Huff, WE; Kubena, LF; Witzel, DA, 1990) |
| "Diazepam treatment alleviates in the first session aversion towards open space and hight in the elevated plus-maze only in the genetically hypertensive rats of both sexes and in the normotensive males." | 1.28 | Animal model of anxiety: effect of acute diazepam treatment in the older adult genetically hypertensive rats of Koletsky type and in the older adult rats of Wistar strain. ( Golda, V; Petr, R, 1989) |
| "The naloxone-treated young, obese and non-obese SHR (controls) exhibited marked reduction of the weight of their pituitary and adrenal glands, whereas the pituitary and adrenal glands of naloxone-treated mature, obese and non-obese/SHR were greatly increased in weight." | 1.27 | Anti-opiate (naloxone) suppression of Cushingoid degenerative changes in obese/SHR. ( McMurtry, JP; Wexler, BC, 1985) |
| "Furthermore, the outcome of acute renal failure is closely related to the extent of catabolism." | 1.27 | Chronic ethanol ingestion enhances catabolism and muscle protease activity in acutely uremic rats. ( Duelk, MJ; Heidland, A; Kulzer, P; Peter, G; Schaefer, RM; Teschner, M; Weissinger, F, 1988) |
| "Pretreatment with metyrapone (a corticosterone synthesis inhibitor 150 mg/kg i." | 1.27 | Central serotonergic responses and behavioural adaptation to repeated immobilisation: the effect of the corticosterone synthesis inhibitor metyrapone. ( Curzon, G; Dickinson, SL; Kennett, GA, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 65 (3.68) | 18.7374 |
| 1990's | 84 (4.75) | 18.2507 |
| 2000's | 398 (22.52) | 29.6817 |
| 2010's | 1019 (57.67) | 24.3611 |
| 2020's | 201 (11.38) | 2.80 |
| Authors | Studies |
|---|---|
| Więckowska, A | 1 |
| Więckowski, K | 1 |
| Bajda, M | 1 |
| Brus, B | 1 |
| Sałat, K | 1 |
| Czerwińska, P | 1 |
| Gobec, S | 1 |
| Filipek, B | 1 |
| Malawska, B | 1 |
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 2 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 6 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Turcu, AL | 1 |
| Companys-Alemany, J | 1 |
| Phillips, MB | 1 |
| Patel, DS | 1 |
| Griñán-Ferré, C | 1 |
| Loza, MI | 1 |
| Brea, JM | 1 |
| Pérez, B | 1 |
| Soto, D | 1 |
| Sureda, FX | 1 |
| Kurnikova, MG | 1 |
| Johnson, JW | 1 |
| Pallàs, M | 1 |
| Vázquez, S | 1 |
| García-Eguren, G | 2 |
| González-Ramírez, M | 1 |
| Vizán, P | 1 |
| Giró, O | 2 |
| Vega-Beyhart, A | 1 |
| Boswell, L | 1 |
| Mora, M | 1 |
| Halperin, I | 1 |
| Carmona, F | 1 |
| Gracia, M | 1 |
| Casals, G | 1 |
| Squarcia, M | 1 |
| Enseñat, J | 1 |
| Vidal, O | 1 |
| Di Croce, L | 1 |
| Hanzu, FA | 2 |
| Michalovicz, LT | 6 |
| Kelly, KA | 8 |
| Miller, DB | 8 |
| Sullivan, K | 2 |
| O'Callaghan, JP | 8 |
| Ding, JX | 1 |
| Rudak, PT | 1 |
| Inoue, W | 1 |
| Haeryfar, SMM | 1 |
| Kang, JY | 1 |
| Kim, DY | 1 |
| Lee, JS | 6 |
| Hwang, SJ | 1 |
| Kim, GH | 1 |
| Hyun, SH | 1 |
| Son, CG | 4 |
| Bai, G | 1 |
| Qiao, Y | 1 |
| Lo, PC | 1 |
| Song, L | 3 |
| Yang, Y | 7 |
| Duan, L | 1 |
| Wei, S | 3 |
| Li, M | 4 |
| Huang, S | 1 |
| Zhang, B | 3 |
| Wang, Q | 10 |
| Yang, C | 4 |
| Geng, X | 1 |
| Wu, H | 3 |
| Li, Z | 4 |
| Li, C | 6 |
| Chen, D | 2 |
| Zong, J | 1 |
| Liu, Z | 4 |
| Peng, W | 1 |
| Aydin, S | 1 |
| Yazici, ZG | 1 |
| Kilic, C | 1 |
| Ercelen Ozozturk, B | 1 |
| Kilic, FS | 1 |
| Hong, C | 1 |
| Chen, L | 8 |
| Kong, W | 1 |
| Zhang, D | 3 |
| Wang, L | 7 |
| Zhao, J | 3 |
| Zhong, X | 1 |
| Zhang, G | 2 |
| Huang, Z | 2 |
| Qiu, F | 1 |
| Tang, Y | 2 |
| Yang, J | 7 |
| Ye, C | 1 |
| Xu, X | 3 |
| Cai, M | 1 |
| Zhang, Y | 20 |
| Lu, H | 1 |
| Mo, F | 1 |
| Li, H | 7 |
| Shen, H | 3 |
| Yakhkeshi, R | 1 |
| Roshani, F | 1 |
| Akhoundzadeh, K | 1 |
| Shafia, S | 2 |
| Sakurai, K | 1 |
| Itou, T | 1 |
| Morita, M | 1 |
| Kasahara, E | 2 |
| Moriyama, T | 1 |
| Macpherson, T | 1 |
| Ozawa, T | 1 |
| Miyamoto, Y | 2 |
| Yoneda, Y | 1 |
| Sekiyama, A | 2 |
| Oka, M | 1 |
| Hikida, T | 1 |
| Shuster, AL | 1 |
| Rocha, FE | 1 |
| Wayszceyk, S | 1 |
| de Lima, DD | 1 |
| Barauna, SC | 2 |
| Lopes, BG | 1 |
| Alberton, MD | 2 |
| Magro, DDD | 1 |
| Oliveira, TQ | 2 |
| Chaves Filho, AJM | 1 |
| Jucá, PM | 1 |
| Soares, MVR | 1 |
| Cunha, NL | 1 |
| Vieira, CFX | 1 |
| Gadelha Filho, CVJ | 1 |
| Viana, GA | 1 |
| De Oliveira, GMF | 1 |
| Macedo, DS | 4 |
| Vasconcelos, SMM | 5 |
| Wang, M | 4 |
| Milic, M | 1 |
| Gericke, A | 1 |
| Mercieca, K | 1 |
| Liu, H | 6 |
| Ruan, Y | 1 |
| Jiang, S | 3 |
| van Beers, T | 1 |
| von Pein, HD | 1 |
| Müller, MB | 11 |
| Prokosch, V | 1 |
| Desmet, L | 1 |
| Thijs, T | 1 |
| Mas, R | 1 |
| Verbeke, K | 1 |
| Depoortere, I | 1 |
| Kim, YR | 3 |
| Lee, SY | 2 |
| Lee, SM | 1 |
| Shim, I | 6 |
| Lee, MY | 4 |
| Canet, G | 1 |
| Zussy, C | 2 |
| Hernandez, C | 1 |
| Chevallier, N | 1 |
| Marchi, N | 2 |
| Desrumaux, C | 1 |
| Givalois, L | 3 |
| Ngoupaye, GT | 2 |
| Mokgokong, M | 1 |
| Madlala, T | 1 |
| Mabandla, MV | 1 |
| Clark, KA | 1 |
| Shin, AC | 2 |
| Sirivelu, MP | 1 |
| MohanKumar, RC | 1 |
| Maddineni, SR | 1 |
| Ramachandran, R | 1 |
| MohanKumar, PS | 2 |
| MohanKumar, SMJ | 1 |
| Tseilikman, V | 2 |
| Komelkova, M | 2 |
| Kondashevskaya, MV | 4 |
| Manukhina, E | 2 |
| Downey, HF | 4 |
| Chereshnev, V | 1 |
| Chereshneva, M | 1 |
| Platkovskii, P | 1 |
| Goryacheva, A | 1 |
| Pashkov, A | 1 |
| Fedotova, J | 3 |
| Tseilikman, O | 2 |
| Maltseva, N | 1 |
| Cherkasova, O | 1 |
| Steenblock, C | 1 |
| Bornstein, SR | 4 |
| Ettrich, B | 1 |
| Chrousos, GP | 1 |
| Ullmann, E | 1 |
| Onufriev, MV | 3 |
| Moiseeva, YV | 1 |
| Zhanina, MY | 1 |
| Lazareva, NA | 2 |
| Gulyaeva, NV | 3 |
| Komel'kova, MV | 1 |
| Tseilikman, VE | 3 |
| Tseilikman, OB | 3 |
| Artem'yeva, KA | 1 |
| Aleksankina, VV | 1 |
| Boltovskaya, MN | 1 |
| Sarapul'tsev, AP | 1 |
| Popkov, PN | 1 |
| Chereshneva, MV | 1 |
| Chereshnev, VA | 1 |
| Luo, Y | 1 |
| Hou, X | 1 |
| Lu, K | 1 |
| He, Y | 3 |
| Yang, B | 3 |
| Qin, Y | 2 |
| Sanada, K | 1 |
| Ueno, H | 1 |
| Miyamoto, T | 1 |
| Baba, K | 1 |
| Tanaka, K | 2 |
| Nishimura, H | 1 |
| Nishimura, K | 1 |
| Sonoda, S | 1 |
| Yoshimura, M | 2 |
| Maruyama, T | 1 |
| Onaka, T | 2 |
| Otsuji, Y | 1 |
| Kataoka, M | 1 |
| Ueta, Y | 3 |
| Berke, MS | 1 |
| Fensholdt, LKD | 1 |
| Hestehave, S | 1 |
| Kalliokoski, O | 1 |
| Abelson, KSP | 1 |
| Buchecker, V | 1 |
| Koska, I | 1 |
| Pace, C | 1 |
| Talbot, SR | 3 |
| Palme, R | 11 |
| Bleich, A | 3 |
| Potschka, H | 1 |
| Zhang, C | 11 |
| Zhu, L | 5 |
| Lu, S | 1 |
| Bai, M | 2 |
| Li, Y | 12 |
| Xu, E | 1 |
| Dos Santos, BM | 1 |
| Pereira, GC | 1 |
| Piton, E | 1 |
| Fialho, MFP | 1 |
| Becker, G | 1 |
| da Silva Carlotto, M | 1 |
| Camargo, LFM | 1 |
| Ramanzini, LG | 1 |
| Oliveira, SM | 1 |
| Trevisan, G | 1 |
| Zanchet, EM | 1 |
| Pillat, MM | 1 |
| Bochi, GV | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Mindfulness-based Cognitive Therapy on Psychological Distress in People With Parkinson's Disease[NCT05779137] | 124 participants (Anticipated) | Interventional | 2023-04-17 | Recruiting | |||
| Detection of miRNAs in HPA Axis Function in Healthy Subjects[NCT04066647] | Phase 1/Phase 2 | 7 participants (Actual) | Interventional | 2019-05-09 | Terminated (stopped due to Interim analysis shows results opposite of hypothesized.) | ||
| RESET-medication: Glucocorticoid Receptor (GR) Blockade as Diseasemodifying Treatment for Depression With Childhood Trauma[NCT05217758] | Phase 2 | 158 participants (Anticipated) | Interventional | 2021-12-09 | Recruiting | ||
| Perinatal Stress and Gene Influences: Pathways to Infant Vulnerability[NCT00525226] | 1,431 participants (Actual) | Observational | 2007-09-30 | Completed | |||
| The UCSD Suramin Autism Treatment-1 (SAT1) Trial[NCT02508259] | Phase 1/Phase 2 | 10 participants (Actual) | Interventional | 2015-05-31 | Completed | ||
| A Double Blind Placebo Controlled Study on the Effects of a Probiotic on Autonomic and Psychological Stress Responses in Volunteers[NCT02417454] | Phase 3 | 128 participants (Anticipated) | Interventional | 2015-09-30 | Completed | ||
| Identification of Genetic, Immunologic and Microbial Markers of Hirschsprung Associated Enterocolitis in Children With Hirschsprung Disease[NCT02193685] | 400 participants (Anticipated) | Observational | 2010-02-28 | Recruiting | |||
| Total XV - Total Therapy Study XV for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia[NCT00137111] | Phase 3 | 501 participants (Actual) | Interventional | 2000-07-08 | Completed | ||
| Advancing the Multimodal Pathway: Investigating the Use of Sleep and Zolpidem in the Recovery After Shoulder Arthroplasty[NCT03269760] | Phase 1 | 122 participants (Actual) | Interventional | 2017-09-01 | Completed | ||
| Understanding the Neurocognitive Effects of Fecal Microbiota Transplantation in Major Depressive Disorder Patients With and Without Irritable Bowel Syndrome[NCT05174273] | Phase 2/Phase 3 | 180 participants (Anticipated) | Interventional | 2022-04-06 | Recruiting | ||
| "Proof-of-Concept Stress & Anxiety Dampening Effects of Lpc-37"[NCT03494725] | 120 participants (Actual) | Interventional | 2018-04-10 | Completed | |||
| The Efficacy of a Single Dose IV Hydrocortisone Given Within 6 Hours of Exposure to a Traumatic Event in PTSD Prevention[NCT00855270] | 120 participants (Anticipated) | Interventional | 2009-04-30 | Recruiting | |||
| The Interplay Between Addiction to Tobacco Smoking and Sleep Quality Among Healthy Adults[NCT04265339] | 150 participants (Anticipated) | Interventional | 2018-10-15 | Recruiting | |||
| Pioglitazone as an Adjunct for Moderate to Severe Depressive Disorder[NCT01109030] | Phase 2/Phase 3 | 50 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
| Randomized Controlled Experimental Trial Designed to Test the Effects of Probiotics on Mood[NCT03539263] | 39 participants (Actual) | Interventional | 2016-12-20 | Completed | |||
| The Safety and Effectiveness of Probiotic Supplementation on Bipolar Depression: a Proof of Concept Randomized Controlled Trial[NCT02155972] | Phase 2 | 16 participants (Actual) | Interventional | 2013-05-31 | Terminated (stopped due to The trial was terminated because of inability to recruit the needed number of participants) | ||
| A Randomized Controlled Trial of the Safety and Efficacy of Fecal Microbiota Transplantation in a Population With Bipolar Disorder[NCT03279224] | Phase 2/Phase 3 | 35 participants (Actual) | Interventional | 2018-01-01 | Active, not recruiting | ||
| Monocentric STUDY, Randomised Double Blinded (Healthy Subjects, or Transversal (Patients With Gitelman Syndrome)[NCT02297048] | Phase 4 | 26 participants (Actual) | Interventional | 2014-07-31 | Completed | ||
| Effect of One Month of Daily Consumption of Mineral Water Rich in Magnesium on Perceived Stress in Healthy Consumers.[NCT02719925] | 256 participants (Actual) | Interventional | 2016-07-31 | Completed | |||
| Acute and Chronic Impacts of Muscadine Wine Polyphenols on Cognition, Memory, Mood, and Anxiety in Adults Over 50 Years of Age[NCT05541887] | 25 participants (Anticipated) | Interventional | 2023-08-30 | Recruiting | |||
| Stress and Opioid Misuse Risk: The Role of Endogenous Opioid and Endocannabinoid Mechanisms[NCT05142267] | 120 participants (Anticipated) | Interventional | 2022-03-02 | Recruiting | |||
| The Efficacy of the Proximate Administration of Oxytocin After a Traumatic Event in Preventing the Development of Post Traumatic Stress Disorder[NCT01039766] | 24 participants (Anticipated) | Interventional | 2010-02-28 | Recruiting | |||
| A Clinical Trial to Evaluate the Safety and Tolerability of Fecal Microbiota Transplantation in a Population With Obsessive-compulsive Disorder[NCT05720793] | Phase 2 | 20 participants (Anticipated) | Interventional | 2023-06-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The change of miRNA levels in blood between time of injection (baseline) and 60 minutes after injection. Expressed as miRx ratio: miR expression level normalized to miR7-2-1 expression level and divided by miRx expression at baseline (T0). (NCT04066647)
Timeframe: Baseline and 60 minutes
| Intervention | percentage of change (Mean) |
|---|---|
| Dexamethesone | 0.939288216 |
The full ABC is a 58-item parent rating with five factors: Irritability, Social Withdrawal, Stereotypy, Hyperactivity and Inappropriate Speech. Stereotypy is reported, and scores range from 0 to 21, with higher scores indicating worse behavior. A negative difference corresponds to decreased symptoms after treatment. A positive difference corresponds to increased symptoms after treatment. (NCT02508259)
Timeframe: 6 weeks compared to baseline
| Intervention | units on a scale (Mean) |
|---|---|
| Suramin | -4.0 |
| Saline (Placebo) | 1.0 |
ADOS2 comparison scores are units on a scale of 0-10. A score of 7-10 was required for enrollment. A score of 7-10 is diagnostic for autism spectrum disorder (ASD). The higher the score, the more severe the core symptoms of autism spectrum disorder. Scores of 6 and below are considered off the ASD spectrum. (NCT02508259)
Timeframe: 6 weeks compared to baseline
| Intervention | units on a scale (Mean) |
|---|---|
| Suramin | -1.6 |
| Saline (Placebo) | -0.4 |
The reported value is the Language sub-score of the ATEC, and the range for the language sub-score is 0-20. The higher the score, the worse the disability. Outcomes were measured at 6 weeks after treatment compared to baseline. A negative difference corresponds to a decrease in language disability, i.e an improvement in speech and language. A positive difference reflects an increase in language disability, i.e. a decrease in speech and language. (NCT02508259)
Timeframe: 6 weeks
| Intervention | units on a scale (Mean) |
|---|---|
| Suramin | -2.0 |
| Saline (Placebo) | -0.2 |
Expressive One Word Picture Vocabulary Test (EOWPVT) scores are normalized for age. Typical language development produces a mean score of 100 with a standard deviation of 15. Outcomes for EOWPVT were expressed as the mean of the child-specific difference before and 6-weeks after treatment. For example, if the 6-week standard EOWPVT score was 59.6 and the baseline score was 63.8, the difference is -4.2 (= 59.6 - 63.8). A decrease in score at 6 weeks would corresponds to a decrease in language performance, while an increase, a positive difference, would reflect an increase. (NCT02508259)
Timeframe: 6 weeks compared to baseline
| Intervention | units on a scale (Mean) |
|---|---|
| Suramin | -4.2 |
| Saline (Placebo) | 2.0 |
Total repetitive behavior was assessed using the Repetitive behavior questionnaire (RBQ), which has a scale from 0-87. Higher scores correspond to more severe repetitive behavior. Outcomes were analyzed as the difference in the score 6 weeks after treatment compared to baseline. A negative difference corresponds to improved behavior compared to baseline. A positive difference corresponds to worse behavior. (NCT02508259)
Timeframe: 6 weeks compared to baseline
| Intervention | units on a scale (Mean) |
|---|---|
| Suramin | -3.2 |
| Saline (Placebo) | -0.8 |
The CGI-I is scale that ranges from 1-7, reflecting the change in core autism behaviors after treatment. 1 is much improved, 4 is unchanged, and 7 is much worse. (NCT02508259)
Timeframe: Overall ASD symptoms at 6 weeks
| Intervention | units on a scale (Mean) |
|---|---|
| Suramin | -1.8 |
| Saline (Placebo) | 0.0 |
"White blood cell (leukocytes) counts in peripheral blood by Complete Blood Count~Measurement: Percentage change of leukemia cells from baseline" (NCT00137111)
Timeframe: Immediately before the methotrexate infusion and three days after subsequent infusion
| Intervention | Percent change (Mean) |
|---|---|
| 4 hr | -44 |
| 24 hr | -50 |
CCR was measured from end of week 56 therapy to the date of first treatment failure of any kind (relapse, death, lineage switch, or second malignancy) or to the last date of follow-up. Measurement was determined by Kaplan-Meyer estimate. (NCT00137111)
Timeframe: Median follow up time (range) 4.5 (1 to 7.8) years
| Intervention | Percentage of participants (Number) |
|---|---|
| Patients With High Risk of CNS Relapse | 92.2 |
Children were randomly assigned to receive initial single-agent treatment with HDMTX (1g/m^2) as either a 24-hour infusion or a 4-hour infusion and the outcome measure was the accumulation of MTXPG in leukemia cells. (NCT00137111)
Timeframe: 42 hours after start of high dose methotrexate infusion (HDMTX)
| Intervention | pmol/1,000,000,000 cells (Mean) |
|---|---|
| 4 hr | 1688 |
| 24 hr | 2521 |
EFS was measured from the start of on-study to the date of first treatment failure of any kind (relapse, death, lineage switch, or second malignancy) or to the last date of follow-up. Failure to enter remission was considered an event at time zero. Measurement was determined by Kaplan-Meyer estimate. (NCT00137111)
Timeframe: Median follow-up time (range) 5.6 (1.3 to 8.9) years
| Intervention | Percentage of Participants (Number) |
|---|---|
| Total Therapy | 87.3 |
Prednisolone sensitivity was measured in primary leukemia cells from bone marrow collected at diagnosis. Expression of CASP1 was determined by HG-U133A microarray. Values given are gene expression values, and the unit is arbitrary units (AU) defined as scaled fluorescence measured on microarray. (NCT00137111)
Timeframe: Pre-treatment
| Intervention | arbitrary units (Median) | |
|---|---|---|
| Prednisolone-sensitive cells | Prednisolone-resistant cells | |
| Total Therapy | 341.3 | 447.9 |
Prednisolone sensitivity was measured in primary leukemia cells from bone marrow collected at diagnosis. Expression of NLRP3 was determined by HG-U133A microarray. Values given are gene expression values, and the unit is arbitrary units (AU) defined as scaled fluorescence measured on microarray. (NCT00137111)
Timeframe: Pre-treatment
| Intervention | arbitrary units (Median) | |
|---|---|---|
| Prednisolone-sensitive cells | Prednisolone-resistant cells | |
| Total Therapy | 41.2 | 110.7 |
Detection of MRD at end of induction where positive MRD was defined as one or more leukemic cell per 10,000 mononuclear bone-marrow cells (>=0.01%). (NCT00137111)
Timeframe: End of Induction (Day 46 MRD measurement)
| Intervention | participants (Number) | |
|---|---|---|
| Negative <0.01% | Positive >= 0.01% | |
| Total Therapy | 390 | 102 |
Efficacy of the intake of Lpc-37 on reduction of the increase of the diastolic BP in response to the TSST compared to placebo. (NCT03494725)
Timeframe: 3 minutes before the TSST and 1 minute after the TSST after 5 weeks of study product intake
| Intervention | mmHg (Mean) | |
|---|---|---|
| Pre-TSST -3min | Post-TSST +1min | |
| Lpc-37 | 79.13 | 90.38 |
| Placebo | 78.41 | 88.36 |
"Efficacy of the intake of Lpc-37 on the increase of mood scale scores over the course of the treatment~Measured with a daily online diary. Mood was rated by participants on an 11-point scale (0-10; very bad to very well) and monitored through the washout phase (week 1 and 2) and the subsequent treatment phase (weeks 3-7). Higher scores indicate a better mood. Efficacy is defined as an increase, or (in case of a general decrease) reduced decrease for the active treatment group as compared to the placebo group and operationalized as the interaction between time and treatment group. Time is coded as a continuous variable with one average value for each week and participant. Values reflect summary measures for mood ratings on a scale from 0 to 10 for the averaged ratings per participant and week." (NCT03494725)
Timeframe: Daily for 2 weeks before treatment intake and 5 weeks during treatment intake
| Intervention | score (Mean) | ||||||
|---|---|---|---|---|---|---|---|
| Week 1 (run-in) | Week 2 (run-in) | Week 3 (treatment) | Week 4 (treatment) | Week 5 (treatment) | Week 6 (treatment) | Week 7 (treatment) | |
| Lpc-37 | 7.31 | 7.53 | 7.66 | 7.77 | 7.73 | 7.90 | 7.77 |
| Placebo | 7.27 | 7.49 | 7.46 | 7.53 | 7.50 | 7.40 | 7.55 |
"Efficacy of the intake of Lpc-37 on the increase of perceived health status scores over the course of the treatment.~Measured with a daily online diary. Health status was rated by participants on an 11-point scale (0-10; not at all to very) and monitored through the wash-out phase (week 1 and 2) and the subsequent treatment phase (weeks 3-7). Higher scores indicate a high perceived health.Efficacy is defined as an increase, or (in case of a general decrease) reduced decrease for the active treatment group as compared to the placebo group and operationalized as the interaction between time and treatment group. Time is coded as a continuous variable with one value for each day and participant. Values reflect summary measures for perceived health status on a scale from 0 to 10 for the averaged ratings per participant and week." (NCT03494725)
Timeframe: Daily for 2 weeks before treatment intake and 5 weeks during treatment intake
| Intervention | score (Mean) | ||||||
|---|---|---|---|---|---|---|---|
| Week 1 (run-in) | Week 2 (run-in) | Week 3 (treatment) | Week 4 (treatment) | Week 5 (treatment) | Week 6 (treatment) | Week 7 (treatment) | |
| Lpc-37 | 7.80 | 7.89 | 7.88 | 7.91 | 8.05 | 8.11 | 7.91 |
| Placebo | 7.86 | 7.92 | 7.92 | 8.01 | 7.92 | 7.73 | 7.75 |
"Efficacy of the intake of Lpc-37 on the increase of perceived productivity scores over the course of the treatment~Measured with a daily online diary. Productivity was rated by participants on an 11-point scale (0-10; not at all to very) and monitored through the wash-out phase (week 1 and 2) and the subsequent treatment phase (weeks 3-7). Higher scores indicate a higher perceived productivity. Efficacy is defined as an increase, or (in case of a general decrease) reduced decrease for the active treatment group as compared to the placebo group and operationalized as the interaction between time and treatment group.Time is coded as a continuous variable with one value for each day and participant. The values reflect summary measures for perceived productivity on a scale from 0 to 10 for the averaged ratings per participant and week." (NCT03494725)
Timeframe: Daily for 2 weeks before treatment intake and 5 weeks during treatment intake
| Intervention | score (Mean) | ||||||
|---|---|---|---|---|---|---|---|
| Week 1 (run-in) | Week 2 (run-in) | Week 3 (treatment) | Week 4 (treatment) | Week 5 (treatment) | Week 6 (treatment) | Week 7 (treatment) | |
| Lpc-37 | 6.98 | 7.34 | 7.53 | 7.48 | 7.59 | 7.57 | 7.50 |
| Placebo | 7.15 | 7.29 | 7.30 | 7.34 | 7.43 | 7.31 | 7.32 |
"Efficacy of the intake of Lpc-37 on the decrease of reported number of sleep disruptions over the course of the treatment measured with a daily online diary (mean of week summary).~Sleep disruptions were monitored through the wash-out phase (Week 1 and 2) and the subsequent treatment phase (Weeks 3-7). In the count version, the value can be 0 or a natural number for each day and each participant. Efficacy is defined as a decrease, or (in case of a general increase) reduced increase for the active treatment group as compared to the placebo group and operationalized as the interaction between time and treatment group. Time is coded as a continuous variable with one value for each day and participant. Values reflect summary measures for sleep disruptions (count) for the summed counts per participant and week." (NCT03494725)
Timeframe: Daily for 2 weeks before treatment intake and 5 weeks during treatment intake
| Intervention | sleep disruptions per participant & week (Mean) | ||||||
|---|---|---|---|---|---|---|---|
| Week 1 (run-in) | Week 2 (run-in) | Week 3 (treatment) | Week 4 (treatment) | Week 5 (treatment) | Week 6 (treatment) | Week 7 (treatment) | |
| Lpc-37 | 7.30 | 5.50 | 4.89 | 5.43 | 3.52 | 3.80 | 4.66 |
| Placebo | 6.09 | 5.49 | 5.11 | 4.30 | 3.53 | 4.02 | 5.83 |
"Efficacy of the intake of Lpc-37 on the decrease of sleep disruptions over the course of the treatment measured with a daily online diary (Proportion (yes/total)).~Sleep disruptions were monitored through the wash-out phase and the subsequent treatment phase for each week. In the binary version, the value is either Yes or No for each day and each participant.~Efficacy is defined as a decrease, or (in case of a general increase) reduced increase for the active treatment group as compared to the placebo group and operationalized as the interaction between time and treatment group. Time is coded as a continuous variable with one value for each day and participant.~The proportion of participants with at least one sleep disruption by treatment group is given, treatment commenced after week 2. Data listed here reflect the proportion of participants who answered Yes (e.g. 0,477 * 44 = 20.99 participants answered with Yes in week 1 in the Lpc-37 group)." (NCT03494725)
Timeframe: Daily for 2 weeks before treatment intake and 5 weeks during treatment intake
| Intervention | Proportion of participants (yes/total) (Number) | ||||||
|---|---|---|---|---|---|---|---|
| Week 1 (run-in) | Week 2 (run-in) | Week 3 (treatment) | Week 4 (treatment) | Week 5 (treatment) | Week 6 (treatment) | Week 7 (treatment) | |
| Lpc-37 | 0.477 | 0.435 | 0.354 | 0.367 | 0.306 | 0.279 | 0.290 |
| Placebo | 0.465 | 0.426 | 0.418 | 0.310 | 0.292 | 0.331 | 0.389 |
Efficacy of the intake of Lpc-37 on reduction of the increase of salivary Alpha-Amylase (sAA) in response to the TSST compared to placebo. (NCT03494725)
Timeframe: 1 minute before the TSST and 1, 10, 20, 30 and 45 minutes after the TSST after 5 weeks of study product intake
| Intervention | U/ml (Mean) | |||||
|---|---|---|---|---|---|---|
| Pre-TSST -2min | Post-TSST +1min | Post-TSST +10min | Post-TSST +20min | Post-TSST +30min | Post-TSST +45min | |
| Lpc-37 | 154.04 | 246.29 | 146.53 | 130.11 | 125.19 | 141.13 |
| Placebo | 161.67 | 270.55 | 158.85 | 141.49 | 138.48 | 148.15 |
Efficacy of the intake of Lpc-37 on reduction of the increase of salivary cortisol in response to the TSST compared to placebo. (NCT03494725)
Timeframe: 1 minute before the TSST and 1, 10, 20, 30 and 45 minutes after the TSST after 5 weeks of study product intake
| Intervention | nmol/L (Mean) | |||||
|---|---|---|---|---|---|---|
| Pre-TSST -2min | Post-TSST +1min | Post-TSST +10min | Post-TSST +20min | Post-TSST +30min | Post-TSST +45min | |
| Lpc-37 | 4.79 | 6.96 | 9.48 | 9.89 | 8.04 | 6.21 |
| Placebo | 4.82 | 6.85 | 8.97 | 9.21 | 7.71 | 6.16 |
"Efficacy of the intake of Lpc-37 on the increase of sleep duration over the course of the treatment.~Sleep duration was monitored through the wash-out phase (week 1 and 2) and the subsequent treatment phase (weeks 3-7). Efficacy is defined as an increase, or (in case of a general decrease) reduced decrease for the active treatment group as compared to the placebo group and operationalized as the interaction between time and treatment group. Time is coded as a continuous variable with one value for each day and participant. Summary measures for Sleep duration for the averaged ratings per participant and week" (NCT03494725)
Timeframe: Daily for 2 weeks before treatment intake and 5 weeks during treatment intake
| Intervention | min (Mean) | ||||||
|---|---|---|---|---|---|---|---|
| Week 1 (run-in) | Week 2 (run-in) | Week 3 (treatment) | Week 4 (treatment) | Week 5 (treatment) | Week 6 (treatment) | Week 7 (treatment) | |
| Lpc-37 | 447.27 | 444.01 | 449.45 | 450.62 | 454.50 | 450.88 | 445.60 |
| Placebo | 447.45 | 448.13 | 456.90 | 459.81 | 457.26 | 450.16 | 459.66 |
"Efficacy of the intake of Lpc-37 on the increase of sleep related recovery scores over the course of the treatment.~Measured with a daily online diary. Sleep related recovery was rated by participants on an 11-point scale (0-10; not at all to very) and monitored throughout the wash-out phase (Week 1 and 2) and the subsequent treatment phase (weeks 3-7). High scores indicate a high recovery.~Efficacy is defined as an increase, or (in case of a general decrease) reduced decrease for the active treatment group as compared to the placebo group and operationalized as the interaction between time and treatment group. Time is coded as a continuous variable with one value for each day and participant. Summary measures for sleep related recovery for the averaged ratings per participant and week." (NCT03494725)
Timeframe: Daily for 2 weeks before treatment intake and 5 weeks during treatment intake
| Intervention | score (Mean) | ||||||
|---|---|---|---|---|---|---|---|
| Week 1 (run-in) | Week 2 (run-in) | Week 3 (treatment) | Week 4 (treatment) | Week 5 (treatment) | Week 6 (treatment) | Week 7 (treatment) | |
| Lpc-37 | 6.71 | 7.07 | 7.32 | 7.30 | 7.36 | 7.42 | 7.31 |
| Placebo | 6.91 | 7.15 | 7.27 | 7.29 | 7.36 | 7.10 | 7.28 |
"Efficacy of the intake of Lpc-37 on reduction of the increase of STAI-State scores in response to the TSST compared to placebo.~Measured with the german version of the State-Trait-Anxiety Inventory, scale anxiety as a temporary emotional state (STAI-X1). Answers are given on a four-point rating scale ranging from 1=not at all to 4=very true. The score range is 20-80; Higher scores indicate more anxiety." (NCT03494725)
Timeframe: 10 minutes before the TSST and 1 minute after the TSST after 5 weeks of study product intake
| Intervention | score (Mean) | |
|---|---|---|
| Pre-TSST -10min | Post-TSST +1min | |
| Lpc-37 | 36.09 | 42.38 |
| Placebo | 36.83 | 43.60 |
Efficacy of the intake of Lpc-37 on reduction of the increase of the systolic BP in response to the TSST compared to placebo. (NCT03494725)
Timeframe: 3 minutes before the TSST and 1 minute after the TSST after 5 weeks of study product intake
| Intervention | mmHg (Mean) | |
|---|---|---|
| Pre-TSST -3min | Post-TSST +1min | |
| Lpc-37 | 115.11 | 127.47 |
| Placebo | 114.33 | 129.19 |
Efficacy was defined as a lower increase in HR in response to the TSST following intervention with Lpc-37, compared to placebo. (NCT03494725)
Timeframe: Continuous measurement starting 20 minutes before and ending 20 minutes after the TSST after 5 weeks of product intake. Mean values were calculated per group at seven-time windows before, during and after the TSST
| Intervention | bpm (Mean) | ||||||
|---|---|---|---|---|---|---|---|
| Pre-TSST -20min | Pre-TSST -10min | Pre-TSST -3min | during TSST (Interview) | during TSST (Arithmetic) | Post-TSST +10min | Post-TSST +20min | |
| Lpc-37 | 74.84 | 88.15 | 97.34 | 107.56 | 102.77 | 93.32 | 75.88 |
| Placebo | 74.34 | 86.69 | 97.62 | 105.66 | 100.81 | 90.81 | 74.97 |
"Efficacy of the intake of Lpc-37 on reduction of the increase of VAS anxiety scores in response to the TSST compared to placebo.~Measured with a german version of the Visual Analog Scale (VAS) as a 10cm bipolar scale ranging from not at all to highly. The participant indicated his/her actual perception by placing a mark on a line. VAS scores were obtained by using a ruler and measuring the position of the participants's mark with millimeter precision. To control for possible variations due to printing, the total length of the line was also measured and percentage scores for each participant were computed. Percentage scores range from 0-100. Higher scores indicating greater anxiety." (NCT03494725)
Timeframe: 10 minutes before the TSST, during the TSST and 1 minute after the TSST after 5 weeks of study product intake
| Intervention | score (Mean) | ||
|---|---|---|---|
| Pre-TSST -10min | Interview TSST (during) | Post-TSST +1min | |
| Lpc-37 | 6.80 | 20.85 | 10.68 |
| Placebo | 8.50 | 22.47 | 11.74 |
"Efficacy of the intake of Lpc-37 on reduction of the increase of VAS exhaustion scores in response to the TSST compared to placebo.~Measured with a german version of the Visual Analog Scale (VAS) as a 10cm bipolar scale ranging from not at all to highly. The participant indicated his/her actual perception by placing a mark on a line. VAS scores were obtained by using a ruler and measuring the position of the participants's mark with millimeter precision. To control for possible variations due to printing, the total length of the line was also measured and percentage scores for each participant were computed. Percentage scores range from 0-100. Higher scores indicating greater exhaustion." (NCT03494725)
Timeframe: 10 minutes before the TSST, during the TSST and 1 minute after the TSST after 5 weeks of study product intake
| Intervention | score (Mean) | ||
|---|---|---|---|
| Pre-TSST -10min | Interview TSST (during) | Post-TSST +1min | |
| Lpc-37 | 21.18 | 19.20 | 22.12 |
| Placebo | 19.79 | 21.30 | 25.68 |
"Efficacy of the intake of Lpc-37 on reduction of the increase of VAS insecurity scores in response to the TSST compared to placebo.~Measured with a german version of the Visual Analog Scale (VAS) as a 10cm bipolar scale ranging from not at all to highly. The participant indicated his/her actual perception by placing a mark on a line. VAS scores were obtained by using a ruler and measuring the position of the participants's mark with millimeter precision. To control for possible variations due to printing, the total length of the line was also measured and percentage scores for each participant were computed. Percentage scores range from 0-100. Higher scores indicating greater insecurity." (NCT03494725)
Timeframe: 10 minutes before the TSST, during the TSST and 1 minute after the TSST after 5 weeks of study product intake
| Intervention | score (Mean) | ||
|---|---|---|---|
| Pre-TSST -10min | Interview TSST (during) | Post-TSST +1min | |
| Lpc-37 | 14.47 | 45.08 | 23.92 |
| Placebo | 17.19 | 52.19 | 23.69 |
"Efficacy of the intake of Lpc-37 on reduction of the increase of VAS Stress perception scores in response to the TSST compared to placebo.~Measured with a german version of the Visual Analog Scale (VAS) as a 10cm bipolar scale ranging from not at all to highly. The participant indicated his/her actual perception by placing a mark on a line. VAS scores were obtained by using a ruler and measuring the position of the participants's mark with millimeter precision. To control for possible variations due to printing, the total length of the line was also measured and percentage scores for each participant were computed. Percentage scores range from 0-100. Higher scores indicating higher perceived stress." (NCT03494725)
Timeframe: 10 minutes before the TSST, during the TSST and 1 minute after the TSST after 5 weeks of study product intake
| Intervention | score (Mean) | ||
|---|---|---|---|
| Pre-TSST -10min | Interview TSST (during) | Post-TSST +1min | |
| Lpc-37 | 19.89 | 47.71 | 31.72 |
| Placebo | 18.52 | 51.51 | 32.85 |
"Efficacy of the intake of Lpc-37 on the reduction of Beck Anxiety Inventory (BAI) scores compared to placebo.~Measured with the german version of the Beck Anxiety Inventory as a self-rating scale designed to measure anxiety. It comprises 21 sentences describing feelings that can occur when being anxious. These sentences are rated on a four-point rating scale ranging from 0=not at all to 3=severely, considering the last 7 days. The score range is 0-63; Higher scores indicate higher anxiety." (NCT03494725)
Timeframe: Before and after 5 weeks of study product intake.
| Intervention | score (Mean) | |
|---|---|---|
| Baseline | End of Study | |
| Lpc-37 | 5.51 | 4.75 |
| Placebo | 5.85 | 6.33 |
"Efficacy of the intake of Lpc-37 on the reduction of Depression Anxiety Stress Scale (DASS) anxiety scores compared to placebo.~Measured with the german version of the DASS as a 42-item self report instrument designed to measure negative emotional states of depression, anxiety and stress during the past week. The DASS includes three scales (depression, anxiety and stress) of which each scale includes 14 items that are divided into subscales of 2-5 items of similar content.~Items are answered on a four point rating scale ranging from 0 = not at all to 3 = very much. Scores of each scale are calculated by summing the scores for the relevant items.~The anxiety scale assesses autonomic arousal, skeletal muscle effects, situational anxiety, and subjective experience of anxious affect. The items are 2, 4, 7, 9, 15, 19, 20, 23, 25, 28, 30, 36, 40, 41 and individual scores can range from 0 to 42 with higher scores indicating greater severity of the symptoms." (NCT03494725)
Timeframe: Before and after 5 weeks of study product intake.
| Intervention | score (Mean) | |
|---|---|---|
| Baseline | End of Study | |
| Lpc-37 | 2.60 | 2.44 |
| Placebo | 3.07 | 3.45 |
"Efficacy of the intake of Lpc-37 on the reduction of Depression Anxiety Stress Scale (DASS) depression scores compared to placebo.~Measured with the german version of the DASS as a 42-item self report instrument designed to measure negative emotional states of depression, anxiety and stress during the past week. The DASS includes three scales (depression, anxiety and stress) of which each scale includes 14 items that are divided into subscales of 2-5 items of similar content.~Items are answered on a four point rating scale ranging from 0 = not at all to 3 = very much. Scores of each scale are calculated by summing the scores for the relevant items.~The Depression scale assesses dysphoria, hopelessness, devaluation of life, self-deprecation, lack of interest/involvement, anhedonia, and inertia. The items are 3, 5, 10, 13, 16, 17, 21, 24, 26, 31, 34, 37, 38, 42 and individual scores can range from 0 to 42 with higher scores indicating greater severity of the symptoms." (NCT03494725)
Timeframe: Before and after 5 weeks of study product intake.
| Intervention | score (Mean) | |
|---|---|---|
| Baseline | End of Study | |
| Lpc-37 | 4.60 | 4.15 |
| Placebo | 5.21 | 5.10 |
"Efficacy of the intake of Lpc-37 on the reduction of Depression Anxiety Stress Scale (DASS) stress scores compared to placebo.~Measured with the german version of the DASS as a 42-item self report instrument designed to measure negative emotional states of depression, anxiety and stress during the past week. The DASS includes three scales (depression, anxiety and stress) of which each scale includes 14 items that are divided into subscales of 2-5 items of similar content.~Items are answered on a four point rating scale ranging from 0 = not at all to 3 = very much. Scores of each scale are calculated by summing the scores for the relevant items.~The stress scale (items) is sensitive to levels of chronic non-specific arousal.The stress scale items are 1, 6, 8, 11, 12, 14, 18, 22, 27, 29, 32, 33, 35, 39 and individual scores can range from 0 to 42 with higher scores indicating greater severity of the symptoms." (NCT03494725)
Timeframe: Before and after 5 weeks of study product intake.
| Intervention | score (Mean) | |
|---|---|---|
| Baseline | End of Study | |
| Lpc-37 | 9.76 | 8.91 |
| Placebo | 9.41 | 10.09 |
Efficacy of the intake of Lpc-37 on the reduction of diastolic BP. (NCT03494725)
Timeframe: Before and after 5 weeks of study product intake.
| Intervention | mmHg (Mean) | |
|---|---|---|
| Baseline | End of Study | |
| Lpc-37 | 71.89 | 73.18 |
| Placebo | 71.68 | 74.62 |
"Efficacy of the intake of Lpc-37 on the reduction of Perceived Stress Scale (PSS) scores compared to placebo.~Measured with the german version of the PSS as a psychological instrument for measuring stress perception. It assesses how unpredictable, uncontrollable and overloaded participants perceived their lives to have been within the last month. The PSS comprises 14 items that are answered on a five-point rating scale ranging from 0 = never to 4 = very often. Individual scores on the PSS can range from 0 to 56 with higher scores indicating higher perceived stress." (NCT03494725)
Timeframe: Before and after 5 weeks of study product intake.
| Intervention | score (Mean) | |
|---|---|---|
| Baseline | End of Study | |
| Lpc-37 | 21.89 | 20.49 |
| Placebo | 20.72 | 21.56 |
"Efficacy of the intake of Lpc-37 on the reduction of State-Trait-Anxiety-Inventory (STAI)-state scores compared to placebo.~Measured with the german version of the State-Trait-Anxiety Inventory, scale anxiety as a temporary emotional state (STAI-X1). Answers are given on a four-point rating scale ranging from 1=not at all to 4=very true. The score range is 20-80; Higher scores indicate more anxiety." (NCT03494725)
Timeframe: Before and after 5 weeks of study product intake.
| Intervention | score (Mean) | |
|---|---|---|
| Baseline | End of Study | |
| Lpc-37 | 33.65 | 35.18 |
| Placebo | 34.33 | 35.33 |
Efficacy of the intake of Lpc-37 on the reduction of systolic blood pressure (BP). (NCT03494725)
Timeframe: Before and after 5 weeks of study product intake.
| Intervention | mmHg (Mean) | |
|---|---|---|
| Baseline | End of Study | |
| Lpc-37 | 119.60 | 121.87 |
| Placebo | 119.66 | 122.86 |
"Efficacy of the intake of Lpc-37 on the reduction of VAS anxiety scores compared to placebo.~Measured with a german version of the Visual Analog Scale (VAS) as a 10cm bipolar scale ranging from not at all to highly. The participant indicated his/her actual perception by placing a mark on a line. VAS scores were obtained by using a ruler and measuring the position of the participants's mark with millimeter precision. To control for possible variations due to printing, the total length of the line was also measured and percentage scores for each participant were computed. Percentage scores range from 0-100. Higher scores indicating greater anxiety." (NCT03494725)
Timeframe: Before and after 5 weeks of study product intake.
| Intervention | score (Mean) | |
|---|---|---|
| Baseline | End of Study | |
| Lpc-37 | 7.29 | 9.26 |
| Placebo | 7.58 | 7.85 |
"Efficacy of the intake of Lpc-37 on the reduction of VAS exhaustion scores compared to placebo.~Measured with a german version of the Visual Analog Scale (VAS) as a 10cm bipolar scale ranging from not at all to highly. The participant indicated his/her actual perception by placing a mark on a line. VAS scores were obtained by using a ruler and measuring the position of the participants's mark with millimeter precision. To control for possible variations due to printing, the total length of the line was also measured and percentage scores for each participant were computed. Percentage scores range from 0-100. Higher scores indicating greater exhaustion." (NCT03494725)
Timeframe: Before and after 5 weeks of study product intake.
| Intervention | score (Mean) | |
|---|---|---|
| Baseline | End of Study | |
| Lpc-37 | 29.56 | 24.66 |
| Placebo | 23.19 | 18.45 |
"Efficacy of the intake of Lpc-37 on the reduction of VAS insecurity scores compared to placebo.~Measured with a german version of the Visual Analog Scale (VAS) as a 10cm bipolar scale ranging from not at all to highly. The participant indicated his/her actual perception by placing a mark on a line. VAS scores were obtained by using a ruler and measuring the position of the participants's mark with millimeter precision. To control for possible variations due to printing, the total length of the line was also measured and percentage scores for each participant were computed. Percentage scores range from 0-100. Higher scores indicating greater insecurity." (NCT03494725)
Timeframe: Before and after 5 weeks of study product intake.
| Intervention | score (Mean) | |
|---|---|---|
| Baseline | End of Study | |
| Lpc-37 | 13.58 | 16.44 |
| Placebo | 15.91 | 17.30 |
"Efficacy of the intake of Lpc-37 on the reduction of Visual Analog Scale (VAS) stress perception scores compared to placebo.~Measured with a german version of the Visual Analog Scale (VAS) as a 10cm bipolar scale ranging from not at all to highly. The participant indicated his/her actual perception by placing a mark on a line. VAS scores were obtained by using a ruler and measuring the position of the participants's mark with millimeter precision. To control for possible variations due to printing, the total length of the line was also measured and percentage scores for each participant were computed. Percentage scores range from 0-100. Higher scores indicating higher perceived stress." (NCT03494725)
Timeframe: Before and after 5 weeks of study product intake.
| Intervention | score (Mean) | |
|---|---|---|
| Baseline | End of Study | |
| Lpc-37 | 19.11 | 23.32 |
| Placebo | 19.34 | 20.67 |
"Efficacy of the intake of Lpc-37 on the reduction of the difference of cortisol at 8 pm values to the respective mean before and after 5 weeks of treatment~Efficacy for the CAR variable cortisol at 8 pm is defined in terms of a normalization: Number of participants with normal values (between first and third quantile of reference measures) and numbers of participants with low or high values are compared before treatment and after treatment. More participants in the normal range after treatment is defined as efficacy." (NCT03494725)
Timeframe: Baseline (average of 2 days before first product intake) and end of study (average of 2 days before last product intake
| Intervention | number of participants (Number) | |||||
|---|---|---|---|---|---|---|
| Baseline (<25% quantile) | Baseline (25% - 75% quantile) | Baseline (>75% quantile) | End of Study (<25% quantile) | End of Study (25% - 75% quantile) | End of Study (>75% quantile) | |
| Lpc-37 | 4 | 20 | 29 | 3 | 28 | 22 |
| Placebo | 6 | 23 | 26 | 7 | 18 | 30 |
"Efficacy of the intake of Lpc-37 on the reduction of the difference of Cortisol Awakening Response (CAR) area under the curve with respect to the ground (AUCg) values to the respective mean before and after 5 weeks of treatment.~The CAR is summarized in the variables AUCg, AUCi, mean increase and peak value. These cortisol indices are frequently used to describe hypothalamic-pituitary-adrenal axis activity and represent information either of the total cortisol production or of the change in cortisol levels. AUCg is the total area under the curve of all measurements (i.e., the intensity or magnitude of the response).~Efficacy for the CAR variables AUCg is defined in terms of a normalization: Number of participants with normal values (between first and third quantile of reference measures) and numbers of participants with low or high values are compared before treatment and after treatment. More participants in the normal range after treatment is defined as efficacy." (NCT03494725)
Timeframe: Baseline (average of 2 days before first product intake) and end of study (average of 2 days before last product intake)
| Intervention | number of participants (Number) | |||||
|---|---|---|---|---|---|---|
| Baseline (<25% quantile) | Baseline (25% - 75% quantile) | Baseline (>75% quantile) | End of Study (<25% quantile) | End of Study (25% - 75% quantile) | End of Study (>75% quantile) | |
| Lpc-37 | 6 | 36 | 11 | 11 | 28 | 14 |
| Placebo | 12 | 30 | 13 | 7 | 35 | 13 |
"Efficacy of the intake of Lpc-37 on the reduction of the difference of Cortisol at Awakening values to the respective mean before and after 5 weeks of treatment~Efficacy for the CAR variable cortisol at awakening is defined in terms of a normalization: Number of participants with normal values (between first and third quantile of reference measures) and numbers of participants with low or high values are compared before treatment and after treatment. More participants in the normal range after treatment is defined as efficacy." (NCT03494725)
Timeframe: Baseline (average of 2 days before first product intake) and end of study (average of 2 days before last product intake)
| Intervention | number of participants (Number) | |||||
|---|---|---|---|---|---|---|
| Baseline (<25% quantile) | Baseline (25% - 75% quantile) | Baseline (>75% quantile) | End of Study (<25% quantile) | End of Study (25% - 75% quantile) | End of Study (>75% quantile) | |
| Lpc-37 | 14 | 31 | 8 | 19 | 26 | 8 |
| Placebo | 16 | 26 | 13 | 12 | 34 | 9 |
"Efficacy of the intake of Lpc-37 on the reduction of the difference of CAR area under the curve with respect to the increase (AUCi) values to the respective mean before and after the treatment.~The CAR is summarized in the variables AUCg, AUCi, mean increase and peak value. These cortisol indices are frequently used to describe hypothalamic-pituitary-adrenal axis activity and represent information either of the total cortisol production or of the change in cortisol levels. AUCi is calculated with reference to the baseline measurement and it ignores the distance from zero for all measurements and emphasizes the changes over time. Efficacy for the CAR variables AUCi is defined in terms of a normalization: Number of participants with normal values (between first and third quantile of reference measures) and numbers of participants with low or high values are compared before treatment and after treatment. More participants in the normal range after treatment is defined as efficacy." (NCT03494725)
Timeframe: Baseline (average of 2 days before first product intake) and end of study (average of 2 days before last product intake)
| Intervention | number of participants (Number) | |||||
|---|---|---|---|---|---|---|
| Baseline (<25% quantile) | Baseline (25% - 75% quantile) | Baseline (>75% quantile) | End of Study (<25% quantile) | End of Study (25% - 75% quantile) | End of Study (>75% quantile) | |
| Lpc-37 | 16 | 34 | 3 | 15 | 34 | 4 |
| Placebo | 22 | 28 | 5 | 15 | 36 | 4 |
28 reviews available for corticosterone and Disease Models, Animal
| Article | Year |
|---|---|
Topics: Acetylcholine; Acinetobacter baumannii; Actinobacteria; Action Potentials; Adalimumab; Adaptation, P | 2019 |
Insights into the Therapeutic Potential of Glucocorticoid Receptor Modulators for Neurodegenerative Diseases.
Topics: Animals; Corticosterone; Disease Models, Animal; Humans; Inflammation; Models, Biological; Neurodege | 2020 |
Do corticosterone levels predict female depressive-like behavior in rodents?
Topics: Animals; Behavior, Animal; Biomarkers; Corticosterone; Depression; Disease Models, Animal; Female; M | 2021 |
Beneficial Effects of Green Tea Catechins on Female Reproductive Disorders: A Review.
Topics: Angiogenesis Inhibitors; Animals; Antioxidants; Apoptosis; Camellia sinensis; Catechin; Cell Prolife | 2021 |
Early life stress perturbs the function of microglia in the developing rodent brain: New insights and future challenges.
Topics: Animals; Brain; Corticosterone; Disease Models, Animal; Mice; Microglia; Neuronal Plasticity; Stress | 2018 |
Adrenocortical endocrine disruption.
Topics: Adrenal Cortex; Adrenal Insufficiency; Aminoglutethimide; Animals; Cell Line, Tumor; Corticosterone; | 2016 |
Individual vulnerabilities relative for potential pathological conditions.
Topics: Adaptation, Psychological; Amphetamine; Animals; Central Nervous System Stimulants; Corticosterone; | 2016 |
Gender-specific neuroimmunoendocrine aging in a triple-transgenic 3xTg-AD mouse model for Alzheimer's disease and its relation with longevity.
Topics: Aging; Alzheimer Disease; Animals; Corticosterone; Cytokines; Disease Models, Animal; Estrogens; Fem | 2008 |
Neuroendocrine-immunology of experimental Chagas' disease.
Topics: Animals; Chagas Disease; Corticosterone; Disease Models, Animal; Humans; Neurosecretory Systems; Thy | 2009 |
Sex-dependent alterations in response to maternal deprivation in rats.
Topics: Animals; Animals, Newborn; Behavior, Animal; Body Weight; Brain; Cannabinoid Receptor Modulators; Ch | 2009 |
Neuroimmune interactions in stress.
Topics: Animals; Anxiety; Corticosterone; Disease Models, Animal; Humans; Hypothalamo-Hypophyseal System; Im | 2010 |
Behavioral and neurobiological consequences of prolonged glucocorticoid exposure in rats: relevance to depression.
Topics: Adult; Animals; Anxiety; Behavior, Animal; Brain; Cognition; Corticosterone; Depressive Disorder; Di | 2010 |
Gender differences in animal models of posttraumatic stress disorder.
Topics: Adrenal Glands; Androgens; Animals; Corticosterone; Disease Models, Animal; Estrogens; Female; Human | 2011 |
Prenatal stress in birds: pathways, effects, function and perspectives.
Topics: Animals; Behavior, Animal; Birds; Corticosterone; Disease Models, Animal; Embryo, Nonmammalian; Fema | 2011 |
Dietary zinc deficiency in rodents: effects on T-cell development, maturation and phenotypes.
Topics: Animals; Corticosterone; Dietary Supplements; Disease Models, Animal; Flow Cytometry; Hypothalamo-Hy | 2012 |
Aldosterone increases earlier than corticosterone in new animal models of depression: is this an early marker?
Topics: Aldosterone; Animals; Biomarkers; Corticosterone; Depressive Disorder; Disease Models, Animal; Femal | 2012 |
The effect of thymectomy and IL-1 on memory: implications for the relationship between immunity and depression.
Topics: Animals; Corticosterone; Cytokines; Depressive Disorder; Disease Models, Animal; Dopamine; Hormone A | 2002 |
Behavioral and physiologic effects of genetic or pharmacologic inactivation of the substance P receptor (NK1).
Topics: Affect; Animals; Anxiety Disorders; Aprepitant; Autoreceptors; Behavior, Animal; Corticosterone; Dia | 2002 |
Hypothalamo-pituitary-adrenal axis and chronic immune activation.
Topics: Animals; Autoimmune Diseases; Corticosterone; Disease Models, Animal; Humans; Hypothalamo-Hypophysea | 2003 |
[Drug-craving animal models and mechanisms].
Topics: Acetylcholine; Animals; Cannabinoid Receptor Modulators; Corticosterone; Corticotropin-Releasing Hor | 2005 |
A role for corticosterone in impaired intestinal immunity and barrier function in a rodent model of acute alcohol intoxication and burn injury.
Topics: Alcoholic Intoxication; Alcoholism; Animals; Burns; Corticosterone; Disease Models, Animal; Humans; | 2006 |
11beta-hydroxysteroid dehydrogenase type 1 and obesity.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adipose Ti | 2008 |
Dietary restriction and aging.
Topics: Age Factors; Aging; Animals; Blood Glucose; Circadian Rhythm; Corticosterone; Diet, Reducing; Diseas | 1993 |
Factors involved in modulation of NK cell activity by ethanol consumption.
Topics: Alcohol Drinking; Alcoholism; Animals; Corticosterone; Disease Models, Animal; Eating; Ethanol; Huma | 1994 |
Stressor-induced oscillation. A possible model of the bidirectional symptoms in PTSD.
Topics: Animals; Brain; Corticosterone; Disease Models, Animal; Dopamine; Humans; Models, Psychological; Rat | 1997 |
Effects of infantile undernutrition on adult learning in rats: methodological and design problems.
Topics: Animals; Animals, Newborn; Behavior, Animal; Body Weight; Corticosterone; Disease Models, Animal; Em | 1976 |
Modulation of anxiety by beta-carbolines and other benzodiazepine receptor ligands: relationship of pharmacological to biochemical measures of efficacy.
Topics: Animals; Anxiety; Benzodiazepines; Binding, Competitive; Brain; Bridged Bicyclo Compounds; Bridged B | 1987 |
Animal models of mineralocorticoid resistance.
Topics: Aldosterone; Animals; Corticosterone; Desoxycorticosterone; Dexamethasone; Disease Models, Animal; D | 1986 |
4 trials available for corticosterone and Disease Models, Animal
| Article | Year |
|---|---|
Chronic social stress during adolescence: interplay of paroxetine treatment and ageing.
Topics: Adrenal Glands; Aging; Animals; Arginine Vasopressin; Body Weight; Chronic Disease; Corticosterone; | 2013 |
Arginine Vasopressin and Arginine Vasopressin Receptor 1b Involved in Electroacupuncture-Attenuated Hypothalamic-Pituitary-Adrenal Axis Hyperactivity in Hepatectomy Rats.
Topics: Acupuncture Points; Adrenocorticotropic Hormone; Analysis of Variance; Animals; Arginine Vasopressin | 2016 |
A novel chronic social stress paradigm in female mice.
Topics: Adrenocorticotropic Hormone; Animals; Anxiety; Arginine Vasopressin; Body Weight; Corticosterone; Co | 2010 |
Olanzapine reduces physical activity in rats exposed to activity-based anorexia: possible implications for treatment of anorexia nervosa?
Topics: Adipose Tissue; Adolescent; Adrenocorticotropic Hormone; Animals; Anorexia; Antipsychotic Agents; Be | 2005 |
1735 other studies available for corticosterone and Disease Models, Animal
| Article | Year |
|---|---|
Synthesis of new N-benzylpiperidine derivatives as cholinesterase inhibitors with β-amyloid anti-aggregation properties and beneficial effects on memory in vivo.
Topics: Acetylcholinesterase; Alzheimer Disease; Amnesia; Amyloid beta-Peptides; Animals; Blood-Brain Barrie | 2015 |
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Design, synthesis, and in vitro and in vivo characterization of new memantine analogs for Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Caenorhabditis elegans; Disease Models, Animal; Memantine; Mice; Recepto | 2022 |
Glucocorticoid-induced Fingerprints on Visceral Adipose Tissue Transcriptome and Epigenome.
Topics: Administration, Oral; Adrenal Gland Neoplasms; Adult; Animals; Biopsy; Chromatin Immunoprecipitation | 2022 |
The β-adrenergic receptor blocker and anti-inflammatory drug propranolol mitigates brain cytokine expression in a long-term model of Gulf War Illness.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Corticosterone | 2021 |
Physical restraint mouse models to assess immune responses under stress with or without habituation.
Topics: Animals; Corticosterone; Disease Models, Animal; Habituation, Psychophysiologic; Immunity; Mice; Res | 2021 |
Korean Red Ginseng Ameliorates Fatigue via Modulation of 5-HT and Corticosterone in a Sleep-Deprived Mouse Model.
Topics: Animals; Brain; Corticosterone; Disease Models, Animal; Dopamine; Fatigue; Male; Mice; Mice, Inbred | 2021 |
Anti-depressive effects of Jiao-Tai-Wan on CORT-induced depression in mice by inhibiting inflammation and microglia activation.
Topics: Animals; Animals, Outbred Strains; Antidepressive Agents; Behavior, Animal; Corticosterone; Depressi | 2022 |
Jie-Yu-He-Huan Capsule Ameliorates Anxiety-Like Behaviours in Rats Exposed to Chronic Restraint Stress via the cAMP/PKA/CREB/BDNF Signalling Pathway.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Brain-Derived Neurotrophic Factor; Corticosterone; Disease Mo | 2021 |
An overview of the behavioral, neurobiological and morphological effects of topiramate in rats exposed to chronic unpredictable mild stress.
Topics: Animals; Behavior, Animal; Body Weight; Brain-Derived Neurotrophic Factor; Cognition; Corticosterone | 2021 |
Behavioral and Neurochemical Changes in Rats with Recurrent Depression induced by chronic unpredictable stress.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Chro | 2021 |
miR-182 mediated the inhibitory effects of NF-κB on the GPR39/CREB/BDNF pathway in the hippocampus of mice with depressive-like behaviors.
Topics: Animals; Brain-Derived Neurotrophic Factor; Computational Biology; Corticosterone; Cyclic AMP Respon | 2022 |
Effect of treadmill exercise on serum corticosterone, serum and hippocampal BDNF, hippocampal apoptosis and anxiety behavior in an ovariectomized rat model of post-traumatic stress disorder (PTSD).
Topics: Animals; Anxiety; Apoptosis; Brain-Derived Neurotrophic Factor; Corticosterone; Disease Models, Anim | 2022 |
Effects of Importin α1/KPNA1 deletion and adolescent social isolation stress on psychiatric disorder-associated behaviors in mice.
Topics: alpha Karyopherins; Animals; Anxiety; Behavior, Animal; Chemokine CXCL5; Corticosterone; Depression; | 2021 |
Protective effect of Myrcia pubipetala Miq. against the alterations in oxidative stress parameters in an animal model of depression induced by corticosterone.
Topics: Animals; Antioxidants; Catalase; Cerebral Cortex; Corticosterone; Depressive Disorder; Disease Model | 2022 |
Lipoic acid prevents mirtazapine-induced weight gain in mice without impairs its antidepressant-like action in a neuroendocrine model of depression.
Topics: Animals; Antidepressive Agents; Antioxidants; Behavior, Animal; Cognitive Dysfunction; Corticosteron | 2022 |
Chronic social defeat stress causes retinal vascular dysfunction.
Topics: Actins; Adrenal Hyperplasia, Congenital; Animals; Cell Survival; Chronic Disease; Corticosterone; Di | 2021 |
Time-Restricted Feeding in Mice Prevents the Disruption of the Peripheral Circadian Clocks and Its Metabolic Impact during Chronic Jetlag.
Topics: Animals; Chronic Disease; Circadian Clocks; Circadian Rhythm; CLOCK Proteins; Colon; Corticosterone; | 2021 |
Effect of Hibiscus syriacus Linnaeus extract and its active constituent, saponarin, in animal models of stress-induced sleep disturbances and pentobarbital-induced sleep.
Topics: Animals; Apigenin; Cerebral Cortex; Corticosterone; Disease Models, Animal; Electroencephalography; | 2022 |
Chronic Glucocorticoids Consumption Triggers and Worsens Experimental Alzheimer's Disease-Like Pathology by Detrimental Immune Modulations.
Topics: Alzheimer Disease; Animals; Corticosterone; Disease Models, Animal; Drinking Water; Glucocorticoids; | 2022 |
Alteration of the α5 GABA receptor and 5HTT lead to cognitive deficits associated with major depressive-like behaviors in a 14-day combined stress rat model.
Topics: Acetylcholinesterase; Animals; Cognition; Corticosterone; Depression; Depressive Disorder, Major; Di | 2023 |
Evaluation of the Central Effects of Systemic Lentiviral-Mediated Leptin Delivery in Streptozotocin-Induced Diabetic Rats.
Topics: Animals; Corticosterone; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, | 2021 |
A Rat Model of Post-Traumatic Stress Syndrome Causes Phenotype-Associated Morphological Changes and Hypofunction of the Adrenal Gland.
Topics: Adrenal Glands; Animals; Case-Control Studies; Chromatography, High Pressure Liquid; Corticosterone; | 2021 |
A Comparative Study of Koizumi and Longa Methods of Intraluminal Filament Middle Cerebral Artery Occlusion in Rats: Early Corticosterone and Inflammatory Response in the Hippocampus and Frontal Cortex.
Topics: Animals; Corticosterone; Disease Models, Animal; Frontal Lobe; Hippocampus; Infarction, Middle Cereb | 2021 |
New Morphofunctional Criteria for Resistance Profile in Post-Traumatic Stress Disorder Models as Adrenal Dysfunction Trigger.
Topics: Animals; Corticosterone; Disease Models, Animal; Rats; Rats, Wistar; Stress Disorders, Post-Traumati | 2021 |
Topics: Animals; Brain-Derived Neurotrophic Factor; Connexin 43; Corticosterone; Depression; Disease Models, | 2022 |
AVP-eGFP was significantly upregulated by hypovolemia in the parvocellular division of the paraventricular nucleus in the transgenic rats.
Topics: Animals; Arginine Vasopressin; Corticosterone; Corticotropin-Releasing Hormone; Disease Models, Anim | 2022 |
Effects of buprenorphine on model development in an adjuvant-induced monoarthritis rat model.
Topics: Analgesics, Opioid; Animals; Ankle Joint; Arthritis, Experimental; Behavior, Animal; Body Weight; Bu | 2022 |
Toward Evidence-Based Severity Assessment in Mouse Models with Repeated Seizures: (II.) Impact of Surgery and Intrahippocampal Kainate.
Topics: Animals; Corticosterone; Disease Models, Animal; Epilepsy; Kainic Acid; Mice; Seizures; Status Epile | 2023 |
The antidepressant-like effect of formononetin on chronic corticosterone-treated mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corticosterone; | 2022 |
Lower antidepressant response to fluoxetine is associated with anxiety-like behavior, hippocampal oxidative imbalance, and increase on peripheral IL-17 and IFN-γ levels.
Topics: Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Corticosterone; Depression; Disease Model | 2022 |
Something new and something blue: Responses to novelty in a rodent model of depression and epilepsy comorbidity.
Topics: Animals; Anxiety; Comorbidity; Corticosterone; Depression; Disease Models, Animal; Epilepsy; Humans; | 2022 |
Tissue-specific regulation of 11β hydroxysteroid dehydrogenase type-1 mRNA expressions in Cushing's syndrome mouse model.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Corticosterone; Cushing Syndrome; Disease Mode | 2022 |
Reelin has antidepressant-like effects after repeated or singular peripheral injections.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal | 2022 |
Gossypetin- based therapeutics for cognitive dysfunction in chronic unpredictable stress- exposed mice.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cognitive Dysfunction; Corticosterone; Disease Models, A | 2022 |
A single dose of ketamine cannot prevent protracted stress-induced anhedonia and neuroinflammation in rats.
Topics: Anhedonia; Animals; Antidepressive Agents; Carrier Proteins; Corticosterone; Depression; Disease Mod | 2022 |
Prior short-term exercise prevents behavioral and biochemical abnormalities induced by single prolonged stress in a rat model of posttraumatic stress disorder.
Topics: Animals; Brain-Derived Neurotrophic Factor; Corticosterone; Disease Models, Animal; Female; Hippocam | 2022 |
Negative air ion exposure ameliorates depression-like behaviors induced by chronic mild stress in mice.
Topics: Animals; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Ions; Mice; Stress, P | 2022 |
Early life adversity accelerates epileptogenesis and enhances depression-like behaviors in rats.
Topics: Adverse Childhood Experiences; Animals; Corticosterone; Depression; Disease Models, Animal; Epilepsy | 2022 |
Cerebrolysin® and Environmental Enrichment, Alone or in Combination, Ameliorate Anxiety- and Depressive-Like Behaviors in a Post-Ischemic Depression Model in Mice.
Topics: Amino Acids; Animals; Anxiety; Brain-Derived Neurotrophic Factor; Corticosterone; Depression; Diseas | 2022 |
Beneficial effects of prolonged 2-phenylethyl alcohol inhalation on chronic distress-induced anxio-depressive-like phenotype in female mice.
Topics: Animals; Anxiety; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Female; Hypo | 2022 |
Effects of RU486 in Treatment of Traumatic Stress-Induced Glucocorticoid Dysregulation and Fear-Related Abnormalities: Early versus Late Intervention.
Topics: Animals; Corticosterone; Disease Models, Animal; Extinction, Psychological; Fear; Glucocorticoids; M | 2022 |
Topics: Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal | 2022 |
High-frequency ultrasound exposure improves depressive-like behavior in an olfactory bulbectomized rat model of depression.
Topics: Animals; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Male; Olfactory Bulb; | 2022 |
Antidepressant effect of Jujuboside A on corticosterone-induced depression in mice.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Corticosterone; Cyclic AMP Respon | 2022 |
Serum biomarkers based neurotrauma severity scale: a study in the mice model of fluid percussion injury.
Topics: Animals; beta-Endorphin; Biomarkers; Brain Injuries, Traumatic; Corticosterone; Disease Models, Anim | 2022 |
Prophylactic administration of rosmarinic acid ameliorates depression-associated cardiac abnormalities in Wistar rats: Evidence of serotonergic, oxidative, and inflammatory pathways.
Topics: Animals; Behavior, Animal; Biomarkers; Catalase; Cinnamates; Copper; Corticosterone; Depression; Dep | 2022 |
Hippocampal miR-124 Participates in the Pathogenesis of Depression via Regulating the Expression of BDNF in a Chronic Social Defeat Stress Model of Depression.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Corticosterone; Depression; Disea | 2022 |
Icariin Improves Glucocorticoid Resistance in a Murine Model of Asthma with Depression Associated with Enhancement of GR Expression and Function.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Corticosterone; Cytokines; Depression; Disease Models | 2023 |
Social-single prolonged stress as an ether-free candidate animal model of post-traumatic stress disorder: Female and male outcomings.
Topics: Animals; Corticosterone; Dexamethasone; Disease Models, Animal; Ether; Female; Hippocampus; Male; Ra | 2022 |
Brain matrix metalloproteinase-9 activity is altered in the corticosterone mouse model of depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; Depressive Disorder, M | 2023 |
Postpartum depression in rats causes poor maternal care and neurochemical alterations on dams and long-lasting impairment in sociability on the offspring.
Topics: Animals; Corticosterone; Depression, Postpartum; Disease Models, Animal; Female; Lactation; Maternal | 2023 |
Antibiotics-induced depression in mice via the microbiota-gut-brain axis.
Topics: Adrenocorticotropic Hormone; Animals; Anti-Bacterial Agents; Brain-Derived Neurotrophic Factor; Brai | 2022 |
Mechanistic insights into the protective role of eugenol against stress-induced reproductive dysfunction in female rat model.
Topics: Animals; Antioxidants; Corticosterone; Depression; Disease Models, Animal; Estradiol; Eugenol; Femal | 2022 |
Antidepressant effects of cherry leaf decoction on a chronic unpredictable mild stress rat model based on the Glu/GABA-Gln metabolic loop.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Corticosterone; Depression; Disease Mod | 2022 |
β-Arrestin2-biased Drd2 agonist UNC9995 alleviates astrocyte inflammatory injury via interaction between β-arrestin2 and STAT3 in mouse model of depression.
Topics: Animals; Astrocytes; beta-Arrestin 1; beta-Arrestin 2; Corticosterone; Depression; Depressive Disord | 2022 |
Adrenal histological and functional changes after hepatic encephalopathy: From mice model to an integrative bioinformatics analysis.
Topics: Adrenal Glands; Adrenal Insufficiency; Animals; Computational Biology; Corticosterone; Disease Model | 2022 |
Paeoniflorin exhibits antidepressant activity in rats with postpartum depression via the TSPO and BDNF‑mTOR pathways.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Carrier Proteins; Corticosterone; | 2022 |
Resistance Training Modulates Hippocampal Neuroinflammation and Protects Anxiety-Depression-like Dyad Induced by an Emotional Single Prolonged Stress Model.
Topics: Animals; Anxiety; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Hippocampus; | 2023 |
18β-Glycyrrhetinic Acid Ameliorates Neuroinflammation Linked Depressive Behavior Instigated by Chronic Unpredictable Mild Stress via Triggering BDNF/TrkB Signaling Pathway in Rats.
Topics: Adrenocorticotropic Hormone; Animals; Body Weight; Brain-Derived Neurotrophic Factor; Corticosterone | 2023 |
Sex-dependent worsening of NMDA-induced responses, anxiety, hypercortisolemia, and organometry of early peripheral immunoendocrine impairment in adult 3xTg-AD mice and their long-lasting ontogenic modulation by neonatal handling.
Topics: Alzheimer Disease; Animals; Anxiety; Corticosterone; Disease Models, Animal; Female; Male; Mice; Mic | 2023 |
The combination of chronic stress and smoke exacerbated depression-like changes and lung cancer factor expression in A/J mice: Involve inflammation and BDNF dysfunction.
Topics: Animals; Antidepressive Agents; bcl-2-Associated X Protein; Brain-Derived Neurotrophic Factor; Corti | 2022 |
The combination of chronic stress and smoke exacerbated depression-like changes and lung cancer factor expression in A/J mice: Involve inflammation and BDNF dysfunction.
Topics: Animals; Antidepressive Agents; bcl-2-Associated X Protein; Brain-Derived Neurotrophic Factor; Corti | 2022 |
The combination of chronic stress and smoke exacerbated depression-like changes and lung cancer factor expression in A/J mice: Involve inflammation and BDNF dysfunction.
Topics: Animals; Antidepressive Agents; bcl-2-Associated X Protein; Brain-Derived Neurotrophic Factor; Corti | 2022 |
The combination of chronic stress and smoke exacerbated depression-like changes and lung cancer factor expression in A/J mice: Involve inflammation and BDNF dysfunction.
Topics: Animals; Antidepressive Agents; bcl-2-Associated X Protein; Brain-Derived Neurotrophic Factor; Corti | 2022 |
The combination of chronic stress and smoke exacerbated depression-like changes and lung cancer factor expression in A/J mice: Involve inflammation and BDNF dysfunction.
Topics: Animals; Antidepressive Agents; bcl-2-Associated X Protein; Brain-Derived Neurotrophic Factor; Corti | 2022 |
The combination of chronic stress and smoke exacerbated depression-like changes and lung cancer factor expression in A/J mice: Involve inflammation and BDNF dysfunction.
Topics: Animals; Antidepressive Agents; bcl-2-Associated X Protein; Brain-Derived Neurotrophic Factor; Corti | 2022 |
The combination of chronic stress and smoke exacerbated depression-like changes and lung cancer factor expression in A/J mice: Involve inflammation and BDNF dysfunction.
Topics: Animals; Antidepressive Agents; bcl-2-Associated X Protein; Brain-Derived Neurotrophic Factor; Corti | 2022 |
The combination of chronic stress and smoke exacerbated depression-like changes and lung cancer factor expression in A/J mice: Involve inflammation and BDNF dysfunction.
Topics: Animals; Antidepressive Agents; bcl-2-Associated X Protein; Brain-Derived Neurotrophic Factor; Corti | 2022 |
The combination of chronic stress and smoke exacerbated depression-like changes and lung cancer factor expression in A/J mice: Involve inflammation and BDNF dysfunction.
Topics: Animals; Antidepressive Agents; bcl-2-Associated X Protein; Brain-Derived Neurotrophic Factor; Corti | 2022 |
Low-Dose IL-2 Attenuated Depression-like Behaviors and Pathological Changes through Restoring the Balances between IL-6 and TGF-β and between Th17 and Treg in a Chronic Stress-Induced Mouse Model of Depression.
Topics: Animals; Corticosterone; Depression; Disease Models, Animal; Interleukin-12; Interleukin-17; Interle | 2022 |
Low-Dose IL-2 Attenuated Depression-like Behaviors and Pathological Changes through Restoring the Balances between IL-6 and TGF-β and between Th17 and Treg in a Chronic Stress-Induced Mouse Model of Depression.
Topics: Animals; Corticosterone; Depression; Disease Models, Animal; Interleukin-12; Interleukin-17; Interle | 2022 |
Low-Dose IL-2 Attenuated Depression-like Behaviors and Pathological Changes through Restoring the Balances between IL-6 and TGF-β and between Th17 and Treg in a Chronic Stress-Induced Mouse Model of Depression.
Topics: Animals; Corticosterone; Depression; Disease Models, Animal; Interleukin-12; Interleukin-17; Interle | 2022 |
Low-Dose IL-2 Attenuated Depression-like Behaviors and Pathological Changes through Restoring the Balances between IL-6 and TGF-β and between Th17 and Treg in a Chronic Stress-Induced Mouse Model of Depression.
Topics: Animals; Corticosterone; Depression; Disease Models, Animal; Interleukin-12; Interleukin-17; Interle | 2022 |
Low-Dose IL-2 Attenuated Depression-like Behaviors and Pathological Changes through Restoring the Balances between IL-6 and TGF-β and between Th17 and Treg in a Chronic Stress-Induced Mouse Model of Depression.
Topics: Animals; Corticosterone; Depression; Disease Models, Animal; Interleukin-12; Interleukin-17; Interle | 2022 |
Low-Dose IL-2 Attenuated Depression-like Behaviors and Pathological Changes through Restoring the Balances between IL-6 and TGF-β and between Th17 and Treg in a Chronic Stress-Induced Mouse Model of Depression.
Topics: Animals; Corticosterone; Depression; Disease Models, Animal; Interleukin-12; Interleukin-17; Interle | 2022 |
Low-Dose IL-2 Attenuated Depression-like Behaviors and Pathological Changes through Restoring the Balances between IL-6 and TGF-β and between Th17 and Treg in a Chronic Stress-Induced Mouse Model of Depression.
Topics: Animals; Corticosterone; Depression; Disease Models, Animal; Interleukin-12; Interleukin-17; Interle | 2022 |
Low-Dose IL-2 Attenuated Depression-like Behaviors and Pathological Changes through Restoring the Balances between IL-6 and TGF-β and between Th17 and Treg in a Chronic Stress-Induced Mouse Model of Depression.
Topics: Animals; Corticosterone; Depression; Disease Models, Animal; Interleukin-12; Interleukin-17; Interle | 2022 |
Low-Dose IL-2 Attenuated Depression-like Behaviors and Pathological Changes through Restoring the Balances between IL-6 and TGF-β and between Th17 and Treg in a Chronic Stress-Induced Mouse Model of Depression.
Topics: Animals; Corticosterone; Depression; Disease Models, Animal; Interleukin-12; Interleukin-17; Interle | 2022 |
The effect of occlusal disharmony on a chronic stress-induced animal model of gut microbiota dysbiosis.
Topics: Animals; Corticosterone; Disease Models, Animal; Dysbiosis; Gastrointestinal Microbiome; Rats; Rats, | 2023 |
The effect of occlusal disharmony on a chronic stress-induced animal model of gut microbiota dysbiosis.
Topics: Animals; Corticosterone; Disease Models, Animal; Dysbiosis; Gastrointestinal Microbiome; Rats; Rats, | 2023 |
The effect of occlusal disharmony on a chronic stress-induced animal model of gut microbiota dysbiosis.
Topics: Animals; Corticosterone; Disease Models, Animal; Dysbiosis; Gastrointestinal Microbiome; Rats; Rats, | 2023 |
The effect of occlusal disharmony on a chronic stress-induced animal model of gut microbiota dysbiosis.
Topics: Animals; Corticosterone; Disease Models, Animal; Dysbiosis; Gastrointestinal Microbiome; Rats; Rats, | 2023 |
Mechanisms of Susceptibility and Resilience to PTSD: Role of Dopamine Metabolism and BDNF Expression in the Hippocampus.
Topics: Animals; Corticosterone; Disease Models, Animal; Dopamine; Hexobarbital; Hippocampus; Rats; Stress D | 2022 |
Mechanisms of Susceptibility and Resilience to PTSD: Role of Dopamine Metabolism and BDNF Expression in the Hippocampus.
Topics: Animals; Corticosterone; Disease Models, Animal; Dopamine; Hexobarbital; Hippocampus; Rats; Stress D | 2022 |
Mechanisms of Susceptibility and Resilience to PTSD: Role of Dopamine Metabolism and BDNF Expression in the Hippocampus.
Topics: Animals; Corticosterone; Disease Models, Animal; Dopamine; Hexobarbital; Hippocampus; Rats; Stress D | 2022 |
Mechanisms of Susceptibility and Resilience to PTSD: Role of Dopamine Metabolism and BDNF Expression in the Hippocampus.
Topics: Animals; Corticosterone; Disease Models, Animal; Dopamine; Hexobarbital; Hippocampus; Rats; Stress D | 2022 |
Antidepressant-Like Effects of Edaravone and Minocycline: Investigation of Oxidative Stress, Neuroinflammation, Neurotrophic, and Apoptotic Pathways.
Topics: Acetylcholinesterase; Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; | 2022 |
Antidepressant-Like Effects of Edaravone and Minocycline: Investigation of Oxidative Stress, Neuroinflammation, Neurotrophic, and Apoptotic Pathways.
Topics: Acetylcholinesterase; Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; | 2022 |
Antidepressant-Like Effects of Edaravone and Minocycline: Investigation of Oxidative Stress, Neuroinflammation, Neurotrophic, and Apoptotic Pathways.
Topics: Acetylcholinesterase; Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; | 2022 |
Antidepressant-Like Effects of Edaravone and Minocycline: Investigation of Oxidative Stress, Neuroinflammation, Neurotrophic, and Apoptotic Pathways.
Topics: Acetylcholinesterase; Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; | 2022 |
Protective Effects of Kefir Against Unpredictable Chronic Stress Alterations in Mice Central Nervous System, Heart, and Kidney.
Topics: Animals; Antioxidants; Brain-Derived Neurotrophic Factor; Catalase; Central Nervous System; Corticos | 2023 |
MAD2B Blunts Chronic Unpredictable Stress and Corticosterone Stimulation-Induced Depression-Like Behaviors in Mice.
Topics: Animals; Corticosterone; Depression; Disease Models, Animal; Hippocampus; Mice; MicroRNAs; Rats; Str | 2023 |
Antidepressive-Like Effect of
Topics: Aegle; Anhedonia; Animals; Antidepressive Agents; Corticosterone; Depression; Disease Models, Animal | 2022 |
A protocol for establishing a male G×E schizophrenia mouse model.
Topics: Animals; Brain-Derived Neurotrophic Factor; Corticosterone; Disease Models, Animal; Drug Development | 2022 |
Psychological stress induces moderate pathology in the ganglion cell layer in mice.
Topics: Animals; Body Weight; Brain-Derived Neurotrophic Factor; Corticosterone; Disease Models, Animal; Gla | 2022 |
Baicalin Ameliorates Corticosterone-Induced Depression by Promoting Neurodevelopment of Hippocampal via mTOR/GSK3β Pathway.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal | 2023 |
The Hippocampal Response to Acute Corticosterone Elevation Is Altered in a Mouse Model for Angelman Syndrome.
Topics: Angelman Syndrome; Animals; Brain; Corticosterone; Disease Models, Animal; Hippocampus; Mice; Neuron | 2022 |
Brain-Derived Neurotrophic Factor Delivered Intranasally Relieves Post-Traumatic Stress Disorder Symptoms Caused by a Single Prolonged Stress in Rats.
Topics: Animals; Anxiety; Brain-Derived Neurotrophic Factor; Corticosterone; Disease Models, Animal; Hippoca | 2023 |
Early Life Stress in Mice Leads to Impaired Colonic Corticosterone Production and Prolonged Inflammation Following Induction of Colitis.
Topics: Animals; Colitis; Corticosterone; Disease Models, Animal; Female; Glucocorticoids; Inflammation; Mic | 2023 |
Antidepressant-like effect of endogenous SO
Topics: Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal | 2023 |
Investigations on Rho/ROCK signaling in post-traumatic stress disorder-like behavior in mice.
Topics: Animals; Anxiety; Corticosterone; Disease Models, Animal; Mice; Sertraline; Stress Disorders, Post-T | 2023 |
Synergistic effects of combined therapy with cerebrolysin and enriched environment on anxiety-like behavior and spatial cognitive deficits in posttraumatic stress disorder-like mouse model.
Topics: Amino Acids; Animals; Anxiety; Cognition; Corticosterone; Disease Models, Animal; Hippocampus; Memor | 2023 |
Metyrapone abolishes spike-wave discharge seizures in genetic absence epilepsy rats from Strasbourg by reducing stress hormones.
Topics: Animals; Corticosterone; Desoxycorticosterone; Disease Models, Animal; Electroencephalography; Epile | 2023 |
SNS alleviates depression-like behaviors in CUMS mice by regluating dendritic spines via NCOA4-mediated ferritinophagy.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Dendritic Spines; Depression; Dise | 2023 |
Areca catechu L. ameliorates chronic unpredictable mild stress-induced depression behavior in rats by the promotion of the BDNF signaling pathway.
Topics: Animals; Antidepressive Agents; Areca; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corticos | 2023 |
Congenital blindness does not protect against a schizophrenia-related phenotype in rodents.
Topics: Animals; Blindness; Corticosterone; Disease Models, Animal; Female; Male; Methylazoxymethanol Acetat | 2023 |
Anti-depression-like effect of Mogroside V is related to the inhibition of inflammatory and oxidative stress pathways.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; China; Corticos | 2023 |
Wistar-Kyoto rats and chronically stressed Wistar rats present similar depression- and anxiety-like behaviors but different corticosterone and endocannabinoid system modulation.
Topics: Animals; Anxiety; Corticosterone; Depression; Depressive Disorder, Major; Disease Models, Animal; En | 2023 |
Quercetin mitigates depression-like behavior via the suppression of neuroinflammation and oxidative damage in corticosterone-induced mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corticosterone; | 2023 |
Dried Loquat Fruit Extract Containing Chlorogenic Acid Prevents Depressive-like Behaviors Induced by Repeated Corticosteroid Injections in Mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Chlorogenic Acid; Corticosterone; Depression; Dise | 2023 |
Emotional behaviors as well as the hippocampal reelin expression in C57BL/6N male mice chronically treated with corticosterone.
Topics: Animals; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Emotions; Glucocortic | 2023 |
Social avoidance and altered hypothalamic-pituitary-adrenal axis in a mouse model of anxious depression: The role of LPA
Topics: Animals; Corticosterone; Depression; Disease Models, Animal; Humans; Hypothalamo-Hypophyseal System; | 2023 |
Geraniol attenuates behavioral and neurochemical impairments by inhibitions of HPA-axis and oxido-inflammatory perturbations in mice exposed to post-traumatic stress disorder.
Topics: Acetylcholinesterase; Animals; Corticosterone; Disease Models, Animal; Fluoxetine; Hippocampus; Hypo | 2023 |
A comparative analysis of depressive-like behavior: Exploring sex-related differences and insights.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal | 2023 |
11β-HSD1 plays a critical role in trabecular bone loss associated with systemic glucocorticoid therapy.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Cancellous Bone; Corticosterone; Disease Model | 2019 |
Corticosterone-mediated microglia activation affects dendritic spine plasticity and motor learning functions in minimal hepatic encephalopathy.
Topics: Animals; Cognition Disorders; Cognitive Dysfunction; Corticosterone; Dendritic Spines; Disease Model | 2019 |
Co-treatment of piracetam with risperidone rescued extinction deficits in experimental paradigms of post-traumatic stress disorder by restoring the physiological alterations in cortex and hippocampus.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Corticosterone; Disease Models, Animal; Drug Synerg | 2019 |
Hypothalamic-pituitary-adrenal axis responsivity to an acute novel stress in female rats subjected to the chronic mild stress paradigm.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Corticotropin-Releasing Hormone; Disease Model | 2019 |
Effects of cholecalciferol on behavior and production of reactive oxygen species in female mice subjected to corticosterone-induced model of depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Cholecalciferol; Corticosterone; Depression; Disea | 2020 |
Cochlear Glucocorticoid Receptor and Serum Corticosterone Expression in a Rodent Model of Noise-induced Hearing Loss: Comparison of Timing of Dexamethasone Administration.
Topics: Animals; Auditory Threshold; Cell Survival; Cochlea; Corticosterone; Cytokines; Dexamethasone; Disea | 2019 |
An enhanced expression of hypothalamic neuronal nitric oxide synthase in a rat model of simulated transport stress.
Topics: Animals; Corticosterone; Disease Models, Animal; Male; Motion Sickness; Neurons; Nitric Oxide; Nitri | 2019 |
Chronic non-discriminatory social defeat is an effective chronic stress paradigm for both male and female mice.
Topics: Aggression; Animals; Corticosterone; Disease Models, Animal; Estrous Cycle; Female; Male; Mice, Inbr | 2019 |
Correlation among body composition and metabolic regulation in a male mouse model of Cushing's syndrome.
Topics: Adipocytes, White; Adipose Tissue; Adipose Tissue, White; Adrenal Cortex Hormones; Alanine; Alanine | 2020 |
Involvement of brain-derived neurotrophic factor (BDNF) in the long-term memory effects of glucocorticoid stimulation during adolescence/young adulthood.
Topics: Age Factors; Animals; Brain-Derived Neurotrophic Factor; Corticosterone; Disease Models, Animal; Fem | 2020 |
Effects of sleep disruption on stress, nigrostriatal markers, and behavior in a chronic/progressive MPTP male mouse model of parkinsonism.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Corticosterone; Disease Mode | 2019 |
Social instability is an effective chronic stress paradigm for both male and female mice.
Topics: Animals; Antidepressive Agents, Second-Generation; Anxiety; Behavior, Animal; Corticosterone; Diseas | 2019 |
Dammarane sapogenins alleviates depression-like behaviours induced by chronic social defeat stress in mice through the promotion of the BDNF signalling pathway and neurogenesis in the hippocampus.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Corticosterone; Dammaranes; Depre | 2019 |
Association between intravenous ketamine-induced stress hormone levels and long-term fear memory renewal in Sprague-Dawley rats.
Topics: Administration, Intravenous; Anesthetics, Dissociative; Animals; Behavior, Animal; Corticosterone; D | 2020 |
Systematic analysis of severity in a widely used cognitive depression model for mice.
Topics: Animal Welfare; Animals; Body Weight; Corticosterone; Depression; Disease Models, Animal; Helplessne | 2020 |
Crocin-I ameliorates the disruption of lipid metabolism and dysbiosis of the gut microbiota induced by chronic corticosterone in mice.
Topics: Animals; Bacteria; Bacteroidetes; Carotenoids; Cholesterol; Colon; Corticosterone; Crocus; Disease M | 2019 |
Chronic corticosterone aggravates behavioral and neuronal symptomatology in a mouse model of alpha-synuclein pathology.
Topics: alpha-Synuclein; Animals; Behavior, Animal; Brain; Corticosterone; Disease Models, Animal; Dopaminer | 2019 |
Neonatal Immune Activation May Provoke Long-term Depressive Attributes.
Topics: Animals; Animals, Newborn; Corticosterone; Depression; Depressive Disorder; Disease Models, Animal; | 2019 |
Mouse models in burns research: Characterisation of the hypermetabolic response to burn injury.
Topics: Animals; Basal Metabolism; Body Surface Area; Burns; Corticosterone; Cytokines; Disease Models, Anim | 2020 |
Thymol reverses depression-like behaviour and upregulates hippocampal BDNF levels in chronic corticosterone-induced depression model in female mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corticosterone; | 2019 |
Synthetic enhancer compounds, besides acting on biogenic amine system, influence the glutamate transmission and stress response.
Topics: Animals; Anxiety; Behavior, Animal; Benzofurans; Corticosterone; Disease Models, Animal; Drug Synerg | 2020 |
Metabolomic evidence for the therapeutic effect of gentiopicroside in a corticosterone-induced model of depression.
Topics: Animals; Apoptosis; Arachidonic Acid; Cell Line, Tumor; Corticosterone; Depression; Disease Models, | 2019 |
Rapid anti-PTSD-like activity of the TSPO agonist YL-IPA08: Emphasis on brain GABA, neurosteroids and HPA axis function.
Topics: Animals; Behavior, Animal; Carrier Proteins; Corticosterone; Disease Models, Animal; gamma-Aminobuty | 2020 |
Developmental effects of environmental enrichment on selective and auditory sustained attention.
Topics: Age Factors; Animals; Anxiety; Attention; Attention Deficit Disorder with Hyperactivity; Behavior, A | 2020 |
Gamma-aminobutyric acid-producing lactobacilli positively affect metabolism and depressive-like behaviour in a mouse model of metabolic syndrome.
Topics: Adipose Tissue; Animals; Behavior, Animal; Body Weight; Cholesterol; Corticosterone; Depression; Dis | 2019 |
Link between personality and response to THC exposure.
Topics: Animals; Behavior, Animal; Cannabinoid Receptor Agonists; Conditioning, Psychological; Corticosteron | 2020 |
UCP1-independent glucose-lowering effect of leptin in type 1 diabetes: only in conditions of hypoleptinemia.
Topics: Adipose Tissue, Brown; Adipose Tissue, White; Animals; Blood Glucose; Corticosterone; Diabetes Melli | 2020 |
Royal jelly reduces depression-like behavior through possible effects on adrenal steroidogenesis in a murine model of unpredictable chronic mild stress.
Topics: Adrenal Glands; Animals; Body Weight; Chronic Disease; Corticosterone; Depression; Disease Models, A | 2020 |
The Knockdown of TREK-1 in Hippocampal Neurons Attenuate Lipopolysaccharide-Induced Depressive-Like Behavior in Mice.
Topics: Animals; Behavior, Animal; Corticosterone; Cytokines; Dentate Gyrus; Dependovirus; Depressive Disord | 2019 |
Chronic corticosterone administration induces negative valence and impairs positive valence behaviors in mice.
Topics: Animals; Anxiety; Avoidance Learning; Behavior, Animal; Corticosterone; Disease Models, Animal; Lear | 2019 |
Effects of Puerarin on the Ovariectomy-Induced Depressive-Like Behavior in ICR Mice and Its Possible Mechanism of Action.
Topics: Animals; Brain-Derived Neurotrophic Factor; Corticosterone; Depression; Disease Models, Animal; Doub | 2019 |
Differential effects of stress exposure via two types of restraint apparatuses on behavior and plasma corticosterone level in inbred male BALB/cAJcl mice.
Topics: Animals; Anxiety; Behavior, Animal; Body Weight; Corticosterone; Depression; Disease Models, Animal; | 2020 |
Proteomic profiling of the neurons in mice with depressive-like behavior induced by corticosterone and the regulation of berberine: pivotal sites of oxidative phosphorylation.
Topics: Animals; Behavior, Animal; Berberine; Cell Survival; Corticosterone; Depression; Disease Models, Ani | 2019 |
Duloxetine reverses the symptoms of overactive bladder co-existing with depression via the central pathways.
Topics: Acetanilides; Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; Disease | 2020 |
A novel stress re-stress model: modification of re-stressor cue induces long-lasting post-traumatic stress disorder-like symptoms in rats.
Topics: Animals; Anxiety; Behavior, Animal; Cognitive Dysfunction; Corticosterone; Cues; Depression; Disease | 2020 |
Stress adaptation disorders play a role in rat gestational diabetes with oxidative stress and glucose transporter-4 expression.
Topics: Animals; Blood Glucose; Corticosterone; Diabetes, Gestational; Disease Models, Animal; Female; Gener | 2020 |
Prenatal LPS induces sickness behaviour and decreases maternal and predatory behaviours after an LPS challenge.
Topics: Animals; Corticosterone; Disease Models, Animal; Female; Glial Fibrillary Acidic Protein; Gliosis; I | 2020 |
I. inflexus (Thunb.) Kudo extract improves atopic dermatitis and depressive-like behavior in DfE-induced atopic dermatitis-like disease.
Topics: Animals; Behavior, Animal; Cell Line; Corticosterone; Cytokines; Depression; Dermatitis, Atopic; Der | 2020 |
Chronic unpredictable restraint stress increases hippocampal pro-inflammatory cytokines and decreases motivated behavior in rats.
Topics: Animals; Anxiety; Behavior, Animal; Corticosterone; Cytokines; Depression; Disease Models, Animal; H | 2020 |
The enrichment of maternal environment prevents pre-term birth in a mice model.
Topics: Animals; Corticosterone; Disease Models, Animal; Environment; Female; Healthy Lifestyle; Lipopolysac | 2020 |
Atypical antipsychotic drug modulates early life infection induced impairment of hypothalamic-pituitary-adrenal axis: An age related study in mice.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Age Factors; Animals; Antipsychotic Agents; Chromaff | 2020 |
Hippocampal CCR5/RANTES Elevations in a Rodent Model of Post-Traumatic Stress Disorder: Maraviroc (a CCR5 Antagonist) Increases Corticosterone Levels and Enhances Fear Memory Consolidation.
Topics: Adrenal Cortex Hormones; Animals; CCR5 Receptor Antagonists; Chemokine CCL5; Corticosterone; Disease | 2020 |
Valproic acid administration exerts protective effects against stress-related anhedonia in rats.
Topics: Anhedonia; Animals; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Histone De | 2020 |
(S)-norketamine and (2S,6S)-hydroxynorketamine exert potent antidepressant-like effects in a chronic corticosterone-induced mouse model of depression.
Topics: Anhedonia; Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; Disease Mod | 2020 |
Oleuropein Reverses Repeated Corticosterone-Induced Depressive-Like Behavior in mice: Evidence of Modulating Effect on Biogenic Amines.
Topics: Anhedonia; Animals; Behavior, Animal; Biogenic Amines; Brain; Corticosterone; Depression; Disease Mo | 2020 |
Prefrontal cortex infusion of beta-hydroxybutyrate, an endogenous NLRP3 inflammasome inhibitor, produces antidepressant-like effects in a rodent model of depression.
Topics: 3-Hydroxybutyric Acid; Animals; Antidepressive Agents; Corticosterone; Depression; Disease Models, A | 2020 |
Tooth loss early in life induces hippocampal morphology remodeling in senescence-accelerated mouse prone 8 (SAMP8) mice.
Topics: Aging; Animals; Axons; Body Weight; Cognition Disorders; Corticosterone; Dementia; Disease Models, A | 2020 |
Individual susceptibility or resistance to posttraumatic stress disorder-like behaviours.
Topics: Amygdala; Animals; Brain; Corticosterone; Corticotropin-Releasing Hormone; Dentate Gyrus; Disease Mo | 2020 |
Consuming a ketogenic diet leads to altered hypoglycemic counter-regulation in mice.
Topics: Animals; Blood Glucose; Cerebrum; Corticosterone; Diet, Ketogenic; Disease Models, Animal; Feedback, | 2020 |
Grading animal distress and side effects of therapies.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Corticosterone; Dise | 2020 |
Characterization of serum levels of testosterone and corticosterone in a blast and amputation rat model of heterotopic ossification.
Topics: Amputation, Surgical; Animals; Blast Injuries; Corticosterone; Disease Models, Animal; Femur; Imagin | 2020 |
Acclimatization to Middle Attitude Hypoxia Masks the Symptoms of Experimental Posttraumatic Stress Disorder, but Does Not Affect Its Pathogenetic Mechanisms.
Topics: Acclimatization; Altitude; Altitude Sickness; Animals; Corticosterone; Disease Models, Animal; Hypot | 2020 |
Genistein Prevents Single Prolonged Stress-Induced Cognitive Impairment in a Post-Traumatic Stress Disorder Rat Model via Activation of the Serotonergic System.
Topics: Animals; Cognition; Cognitive Dysfunction; Corticosterone; Disease Models, Animal; Genistein; Hippoc | 2020 |
Exploring the anti-stress effects of imatinib and tetrabenazine in cold-water immersion-induced acute stress in mice.
Topics: Acute Disease; Adrenergic Uptake Inhibitors; Animals; Behavior, Animal; Brain; Cold Temperature; Cor | 2020 |
Pituitary Adenylate Cyclase-Activating Polypeptide Prevents Mortality Caused by Septic Peritonitis in Mice.
Topics: Acute Lung Injury; Adrenocorticotropic Hormone; Animals; Cells, Cultured; Corticosterone; Cytokines; | 2020 |
Tandem mass tag-based proteomic analysis reveals the treatment mechanism of Bushen Huoxue Formula on psychological stress-induced premature ovarian insufficiency.
Topics: Angiopoietin-Like Protein 4; Animals; Corticosterone; Disease Models, Animal; Drugs, Chinese Herbal; | 2020 |
The effects of laser stimulation at acupoint ST36 on anxiety-like behaviors and anterior cingulate cortex c-Fos expression in a rat post-traumatic stress disorder model.
Topics: Acupuncture Points; Animals; Anxiety; Behavior, Animal; Cell Nucleus; Corticosterone; Disease Models | 2021 |
Topical Application of A New Herbal Complex, NI-01, Ameliorates House Dust Mite-Induced Atopic Dermatitis in NC/Nga Mice.
Topics: Administration, Topical; Animals; Corticosterone; Dermatitis, Atopic; Disease Models, Animal; Interc | 2020 |
Sepsis survivor mice exhibit a behavioral endocrine syndrome with ventral hippocampal dysfunction.
Topics: Acute Disease; Animals; Anxiety; Behavior, Animal; Corticosterone; Critical Illness; Depression; Dis | 2020 |
High and low anxiety phenotypes in a rat model of complex post-traumatic stress disorder are associated with different alterations in regional brain monoamine neurotransmission.
Topics: Animals; Anxiety; Behavior, Animal; Brain; Corticosterone; Disease Models, Animal; Disease Susceptib | 2020 |
Effects of early life social experience on fear extinction and related glucocorticoid profiles - behavioral and neurochemical approaches in a rat model of PTSD.
Topics: Animals; Brain; Conditioning, Classical; Corticosterone; Disease Models, Animal; Extinction, Psychol | 2020 |
The influence of the duration of chronic unpredictable mild stress on the behavioural responses of C57BL/6J mice.
Topics: Animals; Behavior, Animal; Body Weight; Corticosterone; Depression; Disease Models, Animal; Hindlimb | 2020 |
Ginsenoside 20(S)-protopanaxadiol attenuates depressive-like behaviour and neuroinflammation in chronic unpredictable mild stress-induced depressive rats.
Topics: Animals; Apoptosis; Corticosterone; Cytokines; Depression; Disease Models, Animal; Encephalitis; Gin | 2020 |
Brain stimulation rewarding experience attenuates neonatal clomipramine-induced adulthood anxiety by reversal of pathological changes in the amygdala.
Topics: Amygdala; Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Anxiety; Biogenic Monoamines; | 2020 |
Pitolisant protects mice chronically treated with corticosterone from some behavioral but not metabolic changes in corticosterone-induced depression model.
Topics: Animals; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Histamine H3 Antagoni | 2020 |
Changes in c-fos and p-CREB signaling following exposure to forced swim stress or exogenous corticosterone during morphine-induced place preference are dependent on glucocorticoid receptor in the basolateral amygdala.
Topics: Animals; Basolateral Nuclear Complex; Conditioning, Psychological; Corticosterone; Cyclic AMP Respon | 2020 |
Short-active photoperiod gestation induces psychiatry-relevant behavior in healthy mice but a resiliency to such effects are seen in mice with reduced dopamine transporter expression.
Topics: Animals; Anti-Inflammatory Agents; Behavior, Animal; Corticosterone; Disease Models, Animal; Dopamin | 2020 |
Comparative study of the protective effects of crocin and exercise on long-term potentiation of CA1 in rats under chronic unpredictable stress.
Topics: Animals; Blood Glucose; CA1 Region, Hippocampal; Carotenoids; Corticosterone; Disease Models, Animal | 2020 |
New insights into the effects of caffeine on adult hippocampal neurogenesis in stressed mice: Inhibition of CORT-induced microglia activation.
Topics: Animals; Antidepressive Agents; Caffeine; Corticosterone; Depression; Disease Models, Animal; Hippoc | 2020 |
Morphological Changes in the Large Intestine of Rats Subjected to Chronic Restraint Stress and Treated with Selank.
Topics: Animals; Colon; Corticosterone; Disease Models, Animal; Male; Mast Cells; Oligopeptides; Rats; Rats, | 2020 |
Subthreshold doses of guanosine plus ketamine elicit antidepressant-like effect in a mouse model of depression induced by corticosterone: Role of GR/NF-κB/IDO-1 signaling.
Topics: Animals; Antidepressive Agents; Corticosterone; Depression; Disease Models, Animal; Drug Therapy, Co | 2020 |
Cyclical administration of corticosterone results in aggravation of depression-like behaviors and accompanying downregulations in reelin in an animal model of chronic stress relevant to human recurrent depression.
Topics: Animals; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Down-Regulation; Extr | 2020 |
Beneficial role of central anticholinergic agent in preventing the development of symptoms in mouse model of post-traumatic stress disorder.
Topics: Animals; Behavior, Animal; Corticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; | 2020 |
Chronic stress followed by social isolation promotes depressive-like behaviour, alters microglial and astrocyte biology and reduces hippocampal neurogenesis in male mice.
Topics: Animals; Astrocytes; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Hippocamp | 2021 |
Antidepressant-like effects of Lactobacillus plantarum DP189 in a corticosterone-induced rat model of chronic stress.
Topics: Animals; Antidepressive Agents; Apoptosis; Behavior, Animal; Brain; Chronic Disease; Corticosterone; | 2020 |
β-1,3-glucan Attenuated Chronic Unpredictable Mild Stress-induced Cognitive Impairment in Rodents via Normalizing Corticosterone Levels.
Topics: Animals; beta-Glucans; Cognitive Dysfunction; Corticosterone; Disease Models, Animal; Glucans; Hippo | 2020 |
Chronic Restraint Stress Inhibits the Response to a Second Hit in Adult Male Rats: A Role for BDNF Signaling.
Topics: Animals; Brain-Derived Neurotrophic Factor; Corticosterone; Disease Models, Animal; Male; Phosphatid | 2020 |
Endocrine stress responsivity and social memory in 3xTg-AD female and male mice: A tale of two experiments.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Corticosterone; Disease Models, Animal; Female; M | 2020 |
Curcumin Attenuates Chronic Unpredictable Mild Stress-Induced Depressive-Like Behaviors via Restoring Changes in Oxidative Stress and the Activation of Nrf2 Signaling Pathway in Rats.
Topics: Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corticosterone; Curcumin; Depression; | 2020 |
Indirect exposure to socially defeated conspecifics using recorded video activates the HPA axis and reduces reward sensitivity in mice.
Topics: Anhedonia; Animals; Brain; Choice Behavior; Corticosterone; Depression; Disease Models, Animal; Empa | 2020 |
Early Life Stress Preceding Mild Pediatric Traumatic Brain Injury Increases Neuroinflammation but Does Not Exacerbate Impairment of Cognitive Flexibility during Adolescence.
Topics: Animals; Attention; Body Weight; Brain Concussion; Cognition; Corticosterone; Disease Models, Animal | 2021 |
Antidepressant-like mechanism of honokiol in a rodent model of corticosterone-induced depression.
Topics: Animals; Antidepressive Agents; Biphenyl Compounds; Corticosterone; Depression; Disease Models, Anim | 2020 |
Dicaffeoylquinic acids alleviate memory loss via reduction of oxidative stress in stress-hormone-induced depressive mice.
Topics: Animals; Antidepressive Agents; Antioxidants; Astrocytes; Behavior, Animal; Cells, Cultured; Cortico | 2020 |
Effect of a Synbiotic Containing
Topics: Animals; Colon; Corticosterone; Disease Models, Animal; Feces; Irritable Bowel Syndrome; Lacticaseib | 2020 |
Local steroid activation is a critical mediator of the anti-inflammatory actions of therapeutic glucocorticoids.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Anti-Inflammatory Agents; Arthritis; Corticost | 2021 |
Non-selective orexin-receptor antagonist attenuates stress-re-stress-induced core PTSD-like symptoms in rats: Behavioural and neurochemical analyses.
Topics: Amygdala; Animals; Azepines; Corticosterone; Disease Models, Animal; Male; Orexin Receptor Antagonis | 2021 |
Maternal Separation-Induced Histone Acetylation Correlates with BDNF-Programmed Synaptic Changes in an Animal Model of PTSD with Sex Differences.
Topics: Acetylation; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; CA1 Region, Hippocampal; | 2021 |
Optogenetic stimulation of the liver-projecting melanocortinergic pathway promotes hepatic glucose production.
Topics: Acetylcholine; Action Potentials; Animals; Arcuate Nucleus of Hypothalamus; Blood Glucose; Cholinerg | 2020 |
Adult neurogenesis augmentation attenuates anhedonia and HPA axis dysregulation in a mouse model of chronic stress and depression.
Topics: Anhedonia; Animals; Behavior, Animal; Corticosterone; Depression; Depressive Disorder, Major; Diseas | 2021 |
Decreased GABAergic signaling, fewer parvalbumin-, somatostatin- and calretinin-positive neurons in brain of a rat model of simulated transport stress.
Topics: Animals; Brain; Calbindin 2; Corticosterone; Disease Models, Animal; GABAergic Neurons; gamma-Aminob | 2021 |
Uncaria rhynchophylla ameliorates unpredictable chronic mild stress-induced depression in mice via activating 5-HT
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Computational Biology; Corticosterone; | 2021 |
Microglial Activation Modulates Neuroendocrine Secretion During Experimental Sepsis.
Topics: Animals; Brain; Corticosterone; Disease Models, Animal; Male; Microglia; Minocycline; Neurons; Neuro | 2021 |
Chronic stress and corticosterone exacerbate alcohol-induced tissue injury in the gut-liver-brain axis.
Topics: Animals; Anti-Inflammatory Agents; Brain Injuries; Central Nervous System Depressants; Corticosteron | 2021 |
Maternal Undernutrition Modulates Neonatal Rat Cerebrovascular Structure, Function, and Vulnerability to Mild Hypoxic-Ischemic Injury via Corticosteroid-Dependent and -Independent Mechanisms.
Topics: Animals; Biomarkers; Cerebral Cortex; Corticosterone; Disease Models, Animal; Disease Susceptibility | 2021 |
Characterizing the protracted neurobiological and neuroanatomical effects of paraquat in a murine model of Parkinson's disease.
Topics: Age Factors; Animals; Antigens, Surface; Brain; Caspase 1; Corticosterone; Disease Models, Animal; D | 2021 |
Learned Immobility Produces Enduring Impairment of the HPA Axis Reactivity in Mice without Replicating the Broad Spectrum of Depressive-Like Phenotype.
Topics: Animals; Antidepressive Agents; Anxiety; Anxiety Disorders; Behavior, Animal; Corticosterone; Depres | 2021 |
Protective Effects of Milk Casein on the Brain Function and Behavior in a Mouse Model of Chronic Stress.
Topics: Animals; Behavior, Animal; Brain; Caseins; Corticosterone; Depression; Disease Models, Animal; Mice; | 2021 |
Sex-specific effects of ketogenic diet after pre-exposure to a high-fat, high-sugar diet in rats.
Topics: 3-Hydroxybutyric Acid; Adiposity; Animals; Biomarkers; Blood Glucose; Corticosterone; Diet, High-Fat | 2021 |
Behavioral characterization of a novel Cisd2 mutant mouse.
Topics: Animals; Autophagy-Related Proteins; Behavior, Animal; Cognitive Dysfunction; Corticosterone; Diseas | 2021 |
Transgenerational effects on anxiety-like behavior following adolescent morphine exposure in female rats.
Topics: Age Factors; Animals; Anxiety; Behavior, Animal; Corticosterone; Disease Models, Animal; Estrous Cyc | 2021 |
Metabolic and behavioral features of acute hyperpurinergia and the maternal immune activation mouse model of autism spectrum disorder.
Topics: Acute Disease; Adenosine Triphosphate; Animals; Autism Spectrum Disorder; Behavior, Animal; Body Tem | 2021 |
Carbonyl reductase 1 amplifies glucocorticoid action in adipose tissue and impairs glucose tolerance in lean mice.
Topics: Adipose Tissue; Alcohol Oxidoreductases; Animals; Corticosterone; Diet, High-Fat; Disease Models, An | 2021 |
Is Riparin III a promising drug in the treatment for depression?
Topics: Animals; Behavior, Animal; Benzamides; Corticosterone; Depression; Disease Models, Animal; Female; M | 2021 |
Chronic Inhibition of FAAH Reduces Depressive-Like Behavior and Improves Dentate Gyrus Proliferation after Chronic Unpredictable Stress Exposure.
Topics: Amidohydrolases; Animals; Cell Proliferation; Corticosterone; Dentate Gyrus; Disease Models, Animal; | 2021 |
16α-Bromoepiandrosterone as a new candidate for experimental diabetes-tuberculosis co-morbidity treatment.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Androsterone; Animals; Antitubercular Agents; Comorbidity; Co | 2021 |
Neuroprotective and Antioxidant Effects of Riparin I in a Model of Depression Induced by Corticosterone in Female Mice.
Topics: Animals; Antioxidants; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corticosterone; Depressi | 2022 |
Synergy of oxytocin and citalopram in modulating Itgb3/Chl1 interplay: Relevance to sensitivity to SSRI therapy.
Topics: Animals; Antidepressive Agents; Anxiety; Cell Adhesion Molecules; Citalopram; Corticosterone; Depres | 2021 |
Amygdala microglia modify neuronal plasticity via complement C1q/C3-CR3 signaling and contribute to visceral pain in a rat model.
Topics: Amygdala; Animals; Colon; Complement C1q; Complement C3; Corticosterone; Disease Models, Animal; Fem | 2021 |
Antidepressant-like effects of acupuncture via modulation of corticosterone, sex hormones, and hippocampal BDNF expression in male rats.
Topics: Acupuncture Therapy; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corticosterone; D | 2021 |
Kamikihito, a traditional Japanese Kampo medicine, increases the secretion of oxytocin in rats with acute stress.
Topics: Administration, Oral; Adrenocorticotropic Hormone; Animals; Behavior, Animal; Corticosterone; Defeca | 2021 |
Amelioration of Cognitive and Behavioral Deficits after Traumatic Brain Injury in Coagulation Factor XII Deficient Mice.
Topics: Animals; Brain; Brain Injuries, Traumatic; Cognitive Dysfunction; Corticosterone; Disease Models, An | 2021 |
BDNF Overexpression in the Ventral Hippocampus Promotes Antidepressant- and Anxiolytic-Like Activity in Serotonin Transporter Knockout Rats.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; Brain-Derived Neurotrophic F | 2021 |
Neuroinflammation and Neuronal Loss in the Hippocampus Are Associated with Immediate Posttraumatic Seizures and Corticosterone Elevation in Rats.
Topics: Animals; Biomarkers; Brain Injuries, Traumatic; Cell Count; Cell Death; Corticosterone; Disease Mode | 2021 |
Adolescent intermittent ethanol (AIE) produces sex specific alterations in adult neuroimmune gene expression and ethanol sensitivity that are independent of ethanol metabolism.
Topics: Animals; Behavior, Animal; Binge Drinking; Corticosterone; Disease Models, Animal; Ethanol; Female; | 2021 |
Quantitation of six steroid hormones by ultra-performance liquid chromatography-tandem mass spectrometry in plasma and prefrontal cortex samples from rats with chronic unpredictable mild stress-induced depression.
Topics: Animals; Chromatography, High Pressure Liquid; Corticosterone; Depression; Disease Models, Animal; L | 2021 |
Is PTSD-Phenotype Associated with HPA-Axis Sensitivity? Feedback Inhibition and Other Modulating Factors of Glucocorticoid Signaling Dynamics.
Topics: Animals; Arginine Vasopressin; Behavior, Animal; Brain; Corticosterone; Disease Models, Animal; Huma | 2021 |
Serum Corticosterone and Insulin Resistance as Early Biomarkers in the hAPP23 Overexpressing Mouse Model of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Biomarkers; Cognitive Dysfunction; Corti | 2021 |
Corticosterone Administration Alters White Matter Tract Structure and Reduces Gliosis in the Sub-Acute Phase of Experimental Stroke.
Topics: Animals; Axons; Corpus Callosum; Corticosterone; Disease Models, Animal; Disease Progression; Diseas | 2021 |
Chronic glucocorticoid treatment induces hepatic lipid accumulation and hyperinsulinaemia in part through actions on AgRP neurons.
Topics: Agouti-Related Protein; Animals; Corticosterone; Disease Models, Animal; Glucocorticoids; Humans; Hy | 2021 |
Dietary EPA-Enriched Phospholipids Alleviate Chronic Stress and LPS-Induced Depression- and Anxiety-Like Behavior by Regulating Immunity and Neuroinflammation.
Topics: Animals; Anxiety; Behavior, Animal; Brain; Corticosterone; Depression; Disease Models, Animal; Eicos | 2021 |
Komagataella pastoris KM71H modulates neuroimmune and oxidative stress parameters in animal models of depression: A proposal for a new probiotic with antidepressant-like effect.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Blood-Brain Barrier; Brain; Corticosterone; Depres | 2021 |
Melatonin Ameliorates Corticosterone-Mediated Oxidative Stress-Induced Colitis in Sleep-Deprived Mice Involving Gut Microbiota.
Topics: Animals; Antioxidants; Colitis; Corticosterone; Disease Models, Animal; Gastrointestinal Microbiome; | 2021 |
Legumain knockout improves repeated corticosterone injection-induced depression-like emotional and cognitive deficits.
Topics: Animals; Behavior, Animal; Cognitive Dysfunction; Corticosterone; Cysteine Endopeptidases; Depressio | 2021 |
Immediate stress alters social and object interaction and recognition memory in nearly isogenic rat strains with differing stress reactivity.
Topics: Animals; Corticosterone; Disease Models, Animal; Female; Male; Rats; Rats, Inbred WKY; Restraint, Ph | 2021 |
Behavioral alterations, brain oxidative stress, and elevated levels of corticosterone associated with a pressure injury model in male mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain; Corticosterone; Depression; Disease Models, | 2022 |
Unbiased Screening Identifies Functional Differences in NK Cells After Early Life Psychosocial Stress.
Topics: Adaptive Immunity; Adult; Adverse Childhood Experiences; Animals; Corticosterone; Disease Models, An | 2021 |
Synergistic effects of combined therapy with transcranial photobiomodulation and enriched environment on depressive- and anxiety-like behaviors in a mice model of noise stress.
Topics: Animals; Anxiety; Behavior, Animal; Brain-Derived Neurotrophic Factor; Combined Modality Therapy; Co | 2022 |
Modulating Oxidative Stress Relieves Stress-Induced Behavioral and Cognitive Impairments in Rats.
Topics: Animals; Antioxidants; Brain; Cell Line, Transformed; Cognition Disorders; Corticosterone; Disease M | 2017 |
Oxytocin in corticosterone-induced chronic stress model: Focus on adrenal gland function.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Body Weight; Catecholamines; Chronic Disease; | 2017 |
A Protocol for Generation of a Corticosterone Model of Psychiatric Disorders.
Topics: Animals; Corticosterone; Disease Models, Animal; Drug Implants; Electrophoresis, Gel, Two-Dimensiona | 2017 |
Hydrogen-rich saline attenuates anxiety-like behaviors in morphine-withdrawn mice.
Topics: Adaptation, Ocular; Animals; Anti-Anxiety Agents; Anxiety; Corticosterone; Disease Models, Animal; D | 2017 |
Sexually Dimorphic Changes of Hypocretin (Orexin) in Depression.
Topics: Aged; Aged, 80 and over; Animals; Bipolar Disorder; Corticosterone; Corticotropin-Releasing Hormone; | 2017 |
Highly palatable food access during adolescence increased anxiety-/depression-like behaviors in male, but not in female, rats.
Topics: Animals; Anxiety; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corticosterone; Depression; D | 2018 |
Gastroparesis and lipid metabolism-associated dysbiosis in Wistar-Kyoto rats.
Topics: Animals; Body Weight; Chromatography, Liquid; Corticosterone; Disease Models, Animal; Gastric Emptyi | 2017 |
Cyclical corticosterone administration sensitizes depression-like behavior in rats.
Topics: Animals; Behavior, Animal; Corticosterone; Depressive Disorder; Disease Models, Animal; Dose-Respons | 2017 |
Curcumin reverses the depressive-like behavior and insulin resistance induced by chronic mild stress.
Topics: Animals; Behavior, Animal; Blood Glucose; Corticosterone; Curcumin; Depression; Disease Models, Anim | 2017 |
Depressive behavior induced by unpredictable chronic mild stress increases dentin hypersensitivity in rats.
Topics: Animals; Corticosterone; Dentin Sensitivity; Depression; Disease Models, Animal; Glial Fibrillary Ac | 2017 |
Depletion of adult neurogenesis using the chemotherapy drug temozolomide in mice induces behavioural and biological changes relevant to depression.
Topics: Animals; Antineoplastic Agents, Alkylating; Behavior, Animal; Biochemical Phenomena; Brain; Brain Ne | 2017 |
Complex modulation by stress of the effect of seizures on long term potentiation in mouse hippocampal slices.
Topics: Animals; Anticonvulsants; Atropine; Corticosterone; Diazepam; Disease Models, Animal; Electric Stimu | 2017 |
Stress and corticosterone alter synaptic plasticity in a rat model of Parkinson's disease.
Topics: Adrenalectomy; Animals; Corticosterone; Disease Models, Animal; Dopamine; Male; Membrane Proteins; M | 2017 |
Expression of Disrupted-in-schizophrenia 1 in Hippocampus in Postpartum Depression Animal Models Induced by Pre-pregnancy Stress.
Topics: Animals; Corticosterone; Depression, Postpartum; Disease Models, Animal; Estradiol; Female; Hippocam | 2017 |
Distinct behavioral and brain changes after different durations of the modified multiple platform method on rats: An animal model of central fatigue.
Topics: Animals; Behavior, Animal; Brain; CA1 Region, Hippocampal; Corticosterone; Disease Models, Animal; F | 2017 |
Inactivation of basolateral amygdala prevents chronic immobilization stress-induced memory impairment and associated changes in corticosterone levels.
Topics: Animals; Basolateral Nuclear Complex; Behavior, Animal; Cognitive Dysfunction; Corticosterone; Disea | 2017 |
Corticosterone primes the neuroinflammatory response to Gulf War Illness-relevant organophosphates independently of acetylcholinesterase inhibition.
Topics: Acetylcholinesterase; Animals; Brain; Cholinesterase Inhibitors; Corticosterone; Disease Models, Ani | 2017 |
Brain antioxidant effect of mirtazapine and reversal of sedation by its combination with alpha-lipoic acid in a model of depression induced by corticosterone.
Topics: Animals; Antidepressive Agents, Tricyclic; Antioxidants; Brain; Brain-Derived Neurotrophic Factor; C | 2017 |
Ketamine and Etomidate Down-regulate the Hypothalamic-Pituitary-Adrenal Axis in an Endotoxemic Mouse Model.
Topics: Analgesics; Animals; Corticosterone; Corticotropin-Releasing Hormone; Disease Models, Animal; Down-R | 2017 |
JIEYUANSHEN DECOCTION EXERTS ANTIDEPRESSANT EFFECTS ON DEPRESSIVE RAT MODEL VIA REGULATING HPA AXIS AND THE LEVEL OF AMINO ACIDS NEUROTRANSMITTER.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Chronic Disease; Corticosterone; Cortic | 2017 |
Chronic corticosterone-induced impaired cognitive flexibility is not due to suppressed adult hippocampal neurogenesis.
Topics: Animals; Bromodeoxyuridine; Cell Survival; Cognition; Corticosterone; Depressive Disorder; Disease M | 2017 |
Environmental novelty exacerbates stress hormones and Aβ pathology in an Alzheimer's model.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Corticosterone; D | 2017 |
The immunomodulatory tellurium compound ammonium trichloro (dioxoethylene-O,O') tellurate reduces anxiety-like behavior and corticosterone levels of submissive mice.
Topics: Ammonium Compounds; Animals; Anxiety; Brain-Derived Neurotrophic Factor; Corticosterone; Disease Mod | 2017 |
Anti-stress effects of a GSK-3β inhibitor, AR-A014418, in immobilization stress of variable duration in mice.
Topics: Animals; Behavior, Animal; Brain; Corticosterone; Disease Models, Animal; Glycogen Synthase Kinase 3 | 2017 |
Differential dendritic remodeling in prelimbic cortex of male and female rats during recovery from chronic stress.
Topics: Adrenal Glands; Animals; Body Weight; Cell Size; Chronic Disease; Corticosterone; Dendrites; Disease | 2017 |
Predator odor evokes sex-independent stress responses in male and female Wistar rats and reduces phosphorylation of cyclic-adenosine monophosphate response element binding protein in the male, but not the female hippocampus.
Topics: Animals; Blood Glucose; Corticosterone; CREB-Binding Protein; Cyclic AMP; Disease Models, Animal; Fe | 2017 |
Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling.
Topics: Animals; Cold Temperature; Corticosterone; Diet, High-Fat; Disease Models, Animal; Disease Progressi | 2017 |
Lithium ameliorates sleep deprivation-induced mania-like behavior, hypothalamic-pituitary-adrenal (HPA) axis alterations, oxidative stress and elevations of cytokine concentrations in the brain and serum of mice.
Topics: Adrenocorticotropic Hormone; Animals; Antimanic Agents; Behavior, Animal; Bipolar Disorder; Brain; C | 2017 |
Antidepressive effects of ginsenoside Rg1 via regulation of HPA and HPG axis.
Topics: Affect; Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; Disease Models | 2017 |
Adrenal-derived stress hormones modulate ozone-induced lung injury and inflammation.
Topics: Adrenal Cortex; Adrenal Medulla; Adrenalectomy; Animals; Corticosterone; Cytokines; Disease Models, | 2017 |
Juvenile social isolation affects maternal care in rats: involvement of allopregnanolone.
Topics: Animals; Anxiety; Corticosterone; Disease Models, Animal; Female; Maternal Behavior; Pregnancy; Preg | 2017 |
Saturated high-fat feeding independent of obesity alters hypothalamus-pituitary-adrenal axis function but not anxiety-like behaviour.
Topics: Animals; Anxiety; Anxiety Disorders; Body Weight; Corticosterone; Corticotropin-Releasing Hormone; D | 2017 |
Constitutive differences in glucocorticoid responsiveness to stress are related to variation in aggression and anxiety-related behaviors.
Topics: Adaptation, Psychological; Adrenocorticotropic Hormone; Aggression; Animals; Anxiety; Behavior, Anim | 2017 |
Methyl jasmonate attenuated lipopolysaccharide-induced depressive-like behaviour in mice.
Topics: Acetates; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Brain; | 2017 |
Abstinence from prolonged ethanol exposure affects plasma corticosterone, glucocorticoid receptor signaling and stress-related behaviors.
Topics: Alcohol Drinking; Alcoholism; Animals; Corticosterone; Disease Models, Animal; Ethanol; Hypothalamo- | 2017 |
Preventive Effects of Ginseng Total Saponins on Chronic Corticosterone-Induced Impairment in Astrocyte Structural Plasticity and Hippocampal Atrophy.
Topics: Animals; Antidepressive Agents; Astrocytes; Atrophy; Corticosterone; Depression; Disease Models, Ani | 2017 |
Silymarin ameliorates experimentally induced depressive like behavior in rats: Involvement of hippocampal BDNF signaling, inflammatory cytokines and oxidative stress response.
Topics: Animals; Antidepressive Agents; Antioxidants; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Co | 2017 |
Conservation of Phenotypes in the Roman High- and Low-Avoidance Rat Strains After Embryo Transfer.
Topics: Animals; Anxiety; Avoidance Learning; Corticosterone; Disease Models, Animal; Embryo Transfer; Explo | 2017 |
Effects of high-intensity interval versus mild-intensity endurance training on metabolic phenotype and corticosterone response in rats fed a high-fat or control diet.
Topics: Animals; Biomarkers; Blood Glucose; Body Composition; Body Fat Distribution; Body Weight; Corticoste | 2017 |
Interplay between H6PDH and 11β-HSD1 implicated in the pathogenesis of type 2 diabetes mellitus.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Carbohydrate Dehydrogenases; Cell Line, Tumor; | 2017 |
microRNA-124 targets glucocorticoid receptor and is involved in depression-like behaviors.
Topics: Animals; Antagomirs; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Corticosterone; Depre | 2017 |
Susceptibility and Resilience to Posttraumatic Stress Disorder-like Behaviors in Inbred Mice.
Topics: Animals; Basolateral Nuclear Complex; Behavior, Animal; Corticosterone; Disease Models, Animal; Dise | 2017 |
Corticosterone potentiates DFP-induced neuroinflammation and affects high-order diffusion imaging in a rat model of Gulf War Illness.
Topics: Animals; Brain; Corticosterone; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Enceph | 2018 |
Beta-Adrenergic Blockade Decreases the Neuroimmune Changes in Mice Induced by Cohabitation with an Ehrlich Tumor-Bearing Cage Mate.
Topics: Adrenal Glands; Adrenergic Agents; Animals; Carcinoma, Ehrlich Tumor; Catecholamines; Corticosterone | 2017 |
The ethanol extract of Aquilariae Lignum ameliorates hippocampal oxidative stress in a repeated restraint stress mouse model.
Topics: Animals; Antioxidants; Astrocytes; Corticosterone; Cytokines; Disease Models, Animal; Epinephrine; H | 2017 |
Fluoxetine coupled with zinc in a chronic mild stress model of depression: Providing a reservoir for optimum zinc signaling and neuronal remodeling.
Topics: Animals; Antidepressive Agents, Second-Generation; Brain; Chronic Disease; Corticosterone; Depressio | 2017 |
Adolescent chronic variable social stress influences exploratory behavior and nicotine responses in male, but not female, BALB/cJ mice.
Topics: Age Factors; Analysis of Variance; Animals; Area Under Curve; Avoidance Learning; Choice Behavior; C | 2018 |
Strain-dependent sex differences in a long-term forced swim paradigm.
Topics: Animals; Anxiety; Behavior, Animal; Corticosterone; Disease Models, Animal; Female; Learning; Male; | 2017 |
Persistent effects of acute stress on fear and drug-seeking in a novel model of the comorbidity between post-traumatic stress disorder and addiction.
Topics: Animals; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Conditioning, Operan | 2017 |
Can Ocimum basilicum relieve chronic unpredictable mild stress-induced depression in mice?
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corticosterone; | 2017 |
Metformin and ascorbic acid combination therapy ameliorates type 2 diabetes mellitus and comorbid depression in rats.
Topics: Animals; Ascorbic Acid; Biogenic Monoamines; Blood Glucose; Comorbidity; Corticosterone; Cytokines; | 2017 |
Antidepressant and pro-neurogenic effects of agmatine in a mouse model of stress induced by chronic exposure to corticosterone.
Topics: Agmatine; Anhedonia; Animals; Antidepressive Agents; Cell Proliferation; Corticosterone; Depressive | 2018 |
Targeting the Endocannabinoid/CB1 Receptor System For Treating Major Depression Through Antidepressant Activities of Curcumin and Dexanabinol-Loaded Solid Lipid Nanoparticles.
Topics: Animals; Antidepressive Agents; Apoptosis; Behavior, Animal; Corticosterone; Curcumin; Depressive Di | 2017 |
Chronic stress targets adult neurogenesis preferentially in the suprapyramidal blade of the rat dorsal dentate gyrus.
Topics: Animals; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Cell Count; Cell Proliferation; Cogni | 2018 |
Interaction of Brain-Derived Neurotrophic Factor Val66Met genotype and history of stress in regulation of prepulse inhibition in mice.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Apomorphine; Brain-Derived Neurotrophic Factor; | 2018 |
Vicarious Social Defeat Stress Induces Depression-Related Outcomes in Female Mice.
Topics: Animals; Antidepressive Agents; Avoidance Learning; Body Weight; Chlordiazepoxide; Corticosterone; D | 2018 |
Injection of oxytocin into paraventricular nucleus reverses depressive-like behaviors in the postpartum depression rat model.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; Depression, Postpartum | 2018 |
Age-dependent effects of Armc5 haploinsufficiency on adrenocortical function.
Topics: Adrenal Cortex; Adrenal Glands; Adrenocortical Hyperfunction; Age Factors; Animals; Armadillo Domain | 2017 |
Methyl Jasmonate Ameliorates Unpredictable Chronic Mild Stress-Induced Behavioral and Biochemical Alterations in Mouse Brain.
Topics: Acetates; Animals; Behavior, Animal; Brain; Corticosterone; Cyclopentanes; Disease Models, Animal; G | 2017 |
The BDNF Val66Met polymorphism regulates glucocorticoid-induced corticohippocampal remodeling and behavioral despair.
Topics: Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corticosterone; Depression; Disease Mo | 2017 |
α-Ketoglutarate prevents skeletal muscle protein degradation and muscle atrophy through PHD3/ADRB2 pathway.
Topics: Animals; Corticosterone; Disease Models, Animal; Ketoglutaric Acids; Male; Metabolic Networks and Pa | 2018 |
Blunted basal corticosterone pulsatility predicts post-exposure susceptibility to PTSD phenotype in rats.
Topics: Acoustic Stimulation; Animals; Biomarkers; Corticosterone; Disease Models, Animal; Disease Susceptib | 2018 |
Rehabilitation modality and onset differentially influence whisker sensory hypersensitivity after diffuse traumatic brain injury in the rat.
Topics: AIDS-Related Complex; Analysis of Variance; Animals; Brain Injuries, Traumatic; Corticosterone; Dise | 2017 |
The modification of the ketogenic diet mitigates its stunting effects in rodents.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Body Weight; Corticosterone; Diet, Ketogenic; Dietary | 2018 |
Brain and Hepatic Mt mRNA Is Reduced in Response to Mild Energy Restriction and n-3 Polyunsaturated Fatty Acid Deficiency in Juvenile Rats.
Topics: alpha-Linolenic Acid; Animals; Body Composition; Brain; Caloric Restriction; Copper; Corn Oil; Corti | 2017 |
Molecular changes associated with escitalopram response in a stress-based model of depression.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Citalopram; Corticosterone; Corticotrop | 2018 |
Housing conditions modulate the reinforcing properties of cocaine in adolescent mice that binge on fat.
Topics: Animals; Animals, Outbred Strains; Anxiety; Bulimia; Cocaine; Cocaine-Related Disorders; Conditionin | 2018 |
Chronic social stress Ameliorates psoriasiform dermatitis through upregulation of the Hypothalamic-Pituitary-Adrenal axis.
Topics: Adrenal Cortex Hormones; Animals; Calcitonin Gene-Related Peptide; Corticosterone; Dermatitis; Disea | 2018 |
Effects of CB1 receptor antagonism and stress exposures in adolescence on socioemotional behaviours, neuroendocrine stress responses, and expression of relevant proteins in the hippocampus and prefrontal cortex in rats.
Topics: Age Factors; Animals; Animals, Newborn; Cannabinoid Receptor Antagonists; Corticosterone; Cyclic AMP | 2018 |
Hepatic and hippocampal cytochrome P450 enzyme overexpression during spontaneous recurrent seizures.
Topics: Animals; Calcium-Binding Proteins; Constitutive Androstane Receptor; Corticosterone; Cytochrome P-45 | 2018 |
Chronic social isolation in adaptation of HPA axis to heterotypic stress.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Crowding; Disease Models, Animal; Hypothalamo- | 2017 |
Paroxetine blunts the corticosterone response to swim-induced stress and increases depressive-like behavior in a rat model of postpartum depression.
Topics: Animals; Corticosterone; Depression; Depression, Postpartum; Disease Models, Animal; Female; Male; P | 2018 |
Stress hormones concentrations in the normal microenvironment predict risk for chemically induced cancer in rats.
Topics: 4-Nitroquinoline-1-oxide; Adrenocorticotropic Hormone; Animals; Biomarkers, Tumor; Brain-Derived Neu | 2018 |
Neuropeptide S in the basolateral amygdala mediates an adaptive behavioral stress response in a rat model of posttraumatic stress disorder by increasing the expression of BDNF and the neuropeptide YY1 receptor.
Topics: Adaptation, Psychological; Animals; Basolateral Nuclear Complex; Brain-Derived Neurotrophic Factor; | 2018 |
A Novel Animal Model Simulating the Beginning of Combat Exposure.
Topics: Animals; Cells, Cultured; Combat Disorders; Corticosterone; Disease Models, Animal; Electric Stimula | 2017 |
Sustained administration of corticosterone at stress-like levels after stroke suppressed glial reactivity at sites of thalamic secondary neurodegeneration.
Topics: Animals; Corticosterone; Disease Models, Animal; Male; Mice; Motor Activity; Nerve Degeneration; Neu | 2018 |
Combined corticosterone treatment and chronic restraint stress lead to depression associated with early cognitive deficits in mice.
Topics: Animals; Behavior, Animal; Cognition Disorders; Cognitive Dysfunction; Corticosterone; Depression; D | 2018 |
Insulin-like Growth Factor 1 Mediates Adrenal Development Dysfunction in Offspring Rats Induced by Prenatal Food Restriction.
Topics: Adrenal Gland Diseases; Animals; Body Weight; Cholesterol; Corticosterone; Diet, Reducing; Disease M | 2017 |
Therapeutic potential of silymarin in chronic unpredictable mild stress induced depressive-like behavior in mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Cerebral Cortex; Corticosterone; Depression; Disea | 2018 |
Metabolic and vascular pattern in medial pterygoid muscle is altered by chronic stress in an animal model of hypodontia.
Topics: Animals; Capillaries; Chronic Disease; Corticosterone; Disease Models, Animal; Male; Molar; NAD; Pte | 2018 |
ATP-sensitive potassium-channel inhibitor glibenclamide attenuates HPA axis hyperactivity, depression- and anxiety-related symptoms in a rat model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Anxiety; Corticosterone; Depression; Disease Mode | 2018 |
Chronic corticosterone-induced depression mediates premature aging in rats.
Topics: Aging, Premature; Animals; Anti-Inflammatory Agents; Antioxidants; Chronic Disease; Corticosterone; | 2018 |
Influence of early stress on memory reconsolidation: Implications for post-traumatic stress disorder treatment.
Topics: Adrenergic beta-Antagonists; Animals; Conditioning, Classical; Corticosterone; Disease Models, Anima | 2018 |
Ocimum basilicum improve chronic stress-induced neurodegenerative changes in mice hippocampus.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corticosterone; | 2018 |
Hippocampal astrocyte atrophy in a mouse depression model induced by corticosterone is reversed by fluoxetine instead of benzodiazepine diazepam.
Topics: Animals; Antidepressive Agents; Astrocytes; Atrophy; Corticosterone; Depressive Disorder; Diazepam; | 2018 |
The Role of Musk in Relieving the Neurodegenerative Changes Induced After Exposure to Chronic Stress.
Topics: Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corticosterone; Disease Models, Animal | 2018 |
Translocator protein (TSPO) and stress cascades in mouse models of psychosis with inflammatory disturbances.
Topics: Animals; Corticosterone; Disease Models, Animal; Female; Inflammation; Male; Mice; Mice, Inbred C57B | 2018 |
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Topics: Aging; Animals; Anxiety; Chronic Disease; Cognition; Cognitive Dysfunction; Corticosterone; Depressi | 2018 |
Early life stress determines the effects of glucocorticoids and stress on hippocampal function: Electrophysiological and behavioral evidence respectively.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Body Weight; Conditioning, Psychologic | 2018 |
Antidepressant-Like Effects of Vaccinium bracteatum in Chronic Restraint Stress Mice: Functional Actions and Mechanism Explorations.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Biogenic Monoamines; Brain; Cells, Cultured; Chron | 2018 |
Antidepressant activity of vorinostat is associated with amelioration of oxidative stress and inflammation in a corticosterone-induced chronic stress model in mice.
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents; Antioxidants; Anxiety; Chronic Disease; Co | 2018 |
Ethanol extract of Rehmannia glutinosa exerts antidepressant-like effects on a rat chronic unpredictable mild stress model by involving monoamines and BDNF.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Corticosterone; Depressive Disord | 2018 |
miR-124 antagonizes the antidepressant-like effects of standardized gypenosides in mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corticosterone; | 2018 |
Targeting glucocorticoid receptors prevents the effects of early life stress on amyloid pathology and cognitive performance in APP/PS1 mice.
Topics: Age Factors; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid End | 2018 |
Endogenous GLP-1 in lateral septum contributes to stress-induced hypophagia.
Topics: Animals; Anorexia; Central Nervous System Agents; Corticosterone; Cross-Over Studies; Disease Models | 2018 |
Glucocorticoid receptor gene expression in a CLP-induced ARDS-like rat model treated with dexamethasone and metyrapone.
Topics: Animals; Cecum; Corticosterone; Dexamethasone; Disease Models, Animal; Gene Expression Regulation; L | 2018 |
Corticosterone-Induced Lipogenesis Activation and Lipophagy Inhibition in Chicken Liver Are Alleviated by Maternal Betaine Supplementation.
Topics: Animals; Betaine; Chickens; Corticosterone; Dietary Supplements; Disease Models, Animal; DNA Methyla | 2018 |
Epigenetic impacts of stress priming of the neuroinflammatory response to sarin surrogate in mice: a model of Gulf War illness.
Topics: Animals; Anti-Inflammatory Agents; Brain; Cholinesterase Inhibitors; Chromatin Immunoprecipitation; | 2018 |
Antidepressant effects of magnolol in a mouse model of depression induced by chronic corticosterone injection.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Biphenyl Compounds; Brain-Derived Neurotrophic Fac | 2018 |
Inhibition of Fatty Acid Amide Hydrolase by PF-3845 Alleviates the Nitrergic and Proinflammatory Response in Rat Hippocampus Following Acute Stress.
Topics: Amidohydrolases; Animals; Corticosterone; Cytokines; Disease Models, Animal; Endocannabinoids; Enzym | 2018 |
Maternal exercise increases but concurrent maternal fluoxetine prevents the increase in hippocampal neurogenesis of adult offspring.
Topics: Animals; Anxiety; Corticosterone; Depression, Postpartum; Disease Models, Animal; Doublecortin Domai | 2018 |
Mifepristone attenuates depression-like changes induced by chronic central administration of interleukin-1β in rats.
Topics: Amygdala; Anhedonia; Animals; Antidepressive Agents; Corticosterone; Depressive Disorder; Disease Mo | 2018 |
Previous Early-life Stress Modifies Acute Corticosterone-induced Synaptic Plasticity in the Medial Prefrontal Cortex of Adolescent Rats.
Topics: Animals; Corticosterone; Disease Models, Animal; Gene Expression Regulation; Long-Term Potentiation; | 2018 |
Elevated stress hormone levels and antidepressant treatment starting before pregnancy affect maternal care and litter characteristics in an animal model of depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; Depression, Postpartum | 2018 |
Anxiolytic-like effects of paeoniflorin in an animal model of post traumatic stress disorder.
Topics: Adrenocorticotropic Hormone; Animals; Anti-Anxiety Agents; Behavior, Animal; Corticosterone; Cortico | 2018 |
Polygonum aviculare L. extract reduces fatigue by inhibiting neuroinflammation in restraint-stressed mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Corticosterone; Cytokines; Disease Models, | 2018 |
Maternal protein-free diet during lactation programs male Wistar rat offspring for increased novelty-seeking, locomotor activity, and visuospatial performance.
Topics: Animals; Behavior, Animal; Brain; Corticosterone; Diet, Protein-Restricted; Disease Models, Animal; | 2018 |
Baicalin Modulates APPL2/Glucocorticoid Receptor Signaling Cascade, Promotes Neurogenesis, and Attenuates Emotional and Olfactory Dysfunctions in Chronic Corticosterone-Induced Depression.
Topics: Adaptor Proteins, Signal Transducing; Animals; Anxiety; Behavior, Animal; Brain; Cell Line, Tumor; C | 2018 |
Modulation of GSK-3β/β-Catenin Signaling Contributes to Learning and Memory Impairment in a Rat Model of Depression.
Topics: Animals; beta Catenin; Cognitive Dysfunction; Corticosterone; Depressive Disorder; Disease Models, A | 2018 |
Insulin treatment partially prevents cognitive and hippocampal alterations as well as glucocorticoid dysregulation in early-onset insulin-deficient diabetic rats.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Cognition; Cognitive Dysfunction; Corticostero | 2018 |
Liraglutide attenuates the depressive- and anxiety-like behaviour in the corticosterone induced depression model via improving hippocampal neural plasticity.
Topics: Alzheimer Disease; Animals; Antidepressive Agents; Anxiety; Corticosterone; Depression; Depressive D | 2018 |
Effect of a melanocortin type 2 receptor (MC2R) antagonist on the corticosterone response to hypoxia and ACTH stimulation in the neonatal rat.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Age Factors; Animals; Animals, Newborn; Biomarkers; Cor | 2018 |
A novel PDE9 inhibitor WYQ-C36D ameliorates corticosterone-induced neurotoxicity and depression-like behaviors by cGMP-CREB-related signaling.
Topics: Animals; Cell Line, Transformed; Cognition Disorders; Corticosterone; CREB-Binding Protein; Cyclic G | 2018 |
Curcumin attenuates chronic intermittent hypoxia-induced brain injuries by inhibiting AQP4 and p38 MAPK pathway.
Topics: Animals; Aquaporin 4; Astrocytes; Brain; Brain Edema; Brain Injuries; Chronic Disease; Corticosteron | 2018 |
Corticosterone Signaling and a Lateral Habenula-Ventral Tegmental Area Circuit Modulate Compulsive Self-Injurious Behavior in a Rat Model.
Topics: Animals; Corticosterone; Disease Models, Animal; Habenula; Male; Neural Pathways; Rats; Rats, Spragu | 2018 |
Protective Effects of Crocetin on Depression-like Behavior Induced by Immobilization in Rat.
Topics: Animals; Antioxidants; Carotenoids; Corticosterone; Depression; Disease Models, Animal; Exploratory | 2018 |
High-fructose diet during adolescent development increases neuroinflammation and depressive-like behavior without exacerbating outcomes after stroke.
Topics: Age Factors; Animals; Behavior, Animal; Brain; Corticosterone; Depression; Diet, High-Fat; Disease M | 2018 |
The Neuroinflammatory Phenotype in a Mouse Model of Gulf War Illness is Unrelated to Brain Regional Levels of Acetylcholine as Measured by Quantitative HILIC-UPLC-MS/MS.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Brain; Cholinesterase Inhibitors; Chromatography, High | 2018 |
[Anti-depression mechanism of supercritical CO(2) extract from Compound Chaigui Fang based on network pharmacology].
Topics: Animals; Antidepressive Agents; Computational Biology; Corticosterone; Depression; Disease Models, A | 2016 |
The Lateral Habenula Directs Coping Styles Under Conditions of Stress via Recruitment of the Endocannabinoid System.
Topics: Adaptation, Psychological; Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Corticosterone | 2018 |
3,4-Dihydroxyphenylethanol Assuages Cognitive Impulsivity in Alzheimer's Disease by Attuning HPA-Axis via Differential Crosstalk of α7 nAChR with MicroRNA-124 and HDAC6.
Topics: alpha Karyopherins; alpha7 Nicotinic Acetylcholine Receptor; Alzheimer Disease; Animals; Antioxidant | 2018 |
Chronic restraint stress disturbs meiotic resumption through APC/C-mediated cyclin B1 excessive degradation in mouse oocytes.
Topics: Anaphase-Promoting Complex-Cyclosome; Animals; Corticosterone; Cyclin B1; Disease Models, Animal; Fe | 2018 |
Effects of chronic noise exposure on the microbiome-gut-brain axis in senescence-accelerated prone mice: implications for Alzheimer's disease.
Topics: Aging; Animals; Avoidance Learning; Brain; Claudins; Cognition Disorders; Corticosterone; Cytokines; | 2018 |
Regional alterations of cerebral [
Topics: Animals; Anxiety; Brain; Chronic Disease; Corticosterone; Depression; Disease Models, Animal; Fluori | 2018 |
Alterations in brain microstructure in rats that develop abnormal aggression following peripubertal stress.
Topics: Age Factors; Aggression; Amygdala; Animals; Anxiety; Behavior, Animal; Corticosterone; Disease Model | 2018 |
Neonatal corticosterone mitigates autoimmune neuropsychiatric disorders associated with streptococcus in mice.
Topics: Animals; Animals, Newborn; Autoimmune Diseases; Behavior Observation Techniques; Behavior, Animal; C | 2018 |
Cholecalciferol counteracts depressive-like behavior and oxidative stress induced by repeated corticosterone treatment in mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Cholecalciferol; Corticosterone; Depression; Disea | 2018 |
Amelioration of neurodegeneration and cognitive impairment by Lemon oil in experimental model of Stressed mice.
Topics: Acetylcholinesterase; Animals; Behavior, Animal; Brain; Catalase; Cognition; Cognitive Dysfunction; | 2018 |
Inhibition of adenosine deaminase and xanthine oxidase by valproic acid abates hepatic triglyceride accumulation independent of corticosteroids in female rats treated with estrogen-progestin.
Topics: Adenosine Deaminase; Adenosine Deaminase Inhibitors; Aldosterone; Animals; Contraceptives, Oral, Com | 2018 |
Effect of acute restraint stress in a polytrauma rat model.
Topics: Acute Disease; Adrenocorticotropic Hormone; Animals; Corticosterone; Disease Models, Animal; Male; M | 2018 |
Acth-induced model of depression resistant to tricyclic antidepressants: Neuroendocrine and behavioral changes and influence of long-term magnesium administration.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Corticoste | 2018 |
Chronic forced exercise inhibits stress-induced reinstatement of cocaine conditioned place preference.
Topics: Animals; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Conditioning, Psycho | 2018 |
Riparin II ameliorates corticosterone-induced depressive-like behavior in mice: Role of antioxidant and neurotrophic mechanisms.
Topics: Animals; Antidepressive Agents; Antioxidants; Behavior, Animal; Benzamides; Brain-Derived Neurotroph | 2018 |
Pathophysiology in a model of Gulf War Illness: Contributions of pyridostigmine bromide and stress.
Topics: Animals; Brain; Cholinesterases; Corticosterone; Cytokines; Disease Models, Animal; Gulf War; Male; | 2018 |
Early life stress accelerates age-induced effects on neurogenesis, depression, and metabolic risk.
Topics: Age Factors; Animals; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Doubleco | 2018 |
Comparative effects of stressors on behavioral and neuroimmune responses of fawn-hooded (FH/Wjd) and Wistar rats: Implications for models of depression.
Topics: Animals; Brain Chemistry; Corticosterone; Cytokines; Depression; Disease Models, Animal; Hypothalamo | 2018 |
Hyperbaric oxygen therapy restored traumatic stress-induced dysregulation of fear memory and related neurochemical abnormalities.
Topics: Animals; Biogenic Monoamines; Conditioning, Psychological; Corticosterone; Disease Models, Animal; E | 2019 |
Synergistic action of ursolic acid and metformin in experimental model of insulin resistance and related behavioral alterations.
Topics: Acetylcholinesterase; Adiponectin; Animals; Behavior, Animal; Blood Pressure; Body Weight; Brain; Co | 2018 |
Akebia saponin D reverses corticosterone hypersecretion in an Alzheimer's disease rat model.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipose Tissue; Adrenal Glands; Alzheimer Disease; Amyl | 2018 |
Long-term impact of chronic variable stress in adolescence versus adulthood.
Topics: Adrenocorticotropic Hormone; Age Factors; Animals; Antimanic Agents; Chronic Disease; Corticosterone | 2019 |
An exploration of the aversive properties of 2-deoxy-D-glucose in rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Analysis of Variance; Animals; Beha | 2018 |
The GCs-SGK1-ATP Signaling Pathway in Spinal Astrocytes Underlied Presurgical Anxiety-Induced Postsurgical Hyperalgesia.
Topics: Adenosine Triphosphate; Animals; Anxiety; Astrocytes; Corticosterone; Disease Models, Animal; Hypera | 2019 |
Adiporon, an adiponectin receptor agonist acts as an antidepressant and metabolic regulator in a mouse model of depression.
Topics: Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Corticosterone; Cytokines; Depression; Di | 2018 |
Chronic corticosterone increases ΔFOSB and CRFR1 immunoreactivity in brain regions that modulate aversive conditioning.
Topics: Animals; Anxiety; Anxiety Disorders; Avoidance Learning; Brain; Conditioning, Psychological; Cortico | 2019 |
Targeted sensory enrichment interventions protect against behavioral and neuroendocrine consequences of early life stress.
Topics: Acoustic Stimulation; Animals; Animals, Newborn; Behavior, Animal; Corticosterone; Disease Models, A | 2018 |
Alcohol inhibits T-cell glucose metabolism and hepatitis in ALDH2-deficient mice and humans: roles of acetaldehyde and glucocorticoids.
Topics: Aldehyde Dehydrogenase, Mitochondrial; Animals; Binge Drinking; Concanavalin A; Corticosterone; Dise | 2019 |
Antioxidant and antidepressant-like effects of Eugenia catharinensis D. Legrand in an animal model of depression induced by corticosterone.
Topics: Animals; Antidepressive Agents; Antioxidants; Corticosterone; Depression; Disease Models, Animal; Do | 2018 |
Real-time in vivo two-photon imaging study reveals decreased cerebro-vascular volume and increased blood-brain barrier permeability in chronically stressed mice.
Topics: Animals; Behavior, Animal; Blood Pressure; Blood-Brain Barrier; Body Weight; Chronic Disease; Cortic | 2018 |
Autogenous transplants of adrenal fragments in an animal model.
Topics: Adrenal Cortex; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Animals; Autografts; Cortico | 2018 |
Resveratrol and dimethyl fumarate ameliorate depression-like behaviour in a rat model of chronic unpredictable mild stress.
Topics: Animals; Antidepressive Agents; Antioxidants; Apoptosis; beta Catenin; Brain-Derived Neurotrophic Fa | 2018 |
Depression-like behaviors induced by chronic corticosterone exposure via drinking water: Time-course analysis.
Topics: Animals; Behavior, Animal; Corticosterone; Depression; Depressive Disorder; Disease Models, Animal; | 2018 |
Somatostatin receptor subtype 5 modifies hypothalamic-pituitary-adrenal axis stress function.
Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Animals; Cell Line, Tumor; Corticosterone; Corti | 2018 |
Repetitive neonatal pain and reduced maternal care alter brain neurochemistry.
Topics: Animals; Corticosterone; Disease Models, Animal; Female; Frontal Lobe; Glutamic Acid; Hippocampus; I | 2018 |
Normalizing glucocorticoid levels attenuates metabolic and neuropathological symptoms in the R6/2 mouse model of huntington's disease.
Topics: Adrenalectomy; Animals; Atrophy; Body Weight; Brain; Corticosterone; Disease Models, Animal; Eating; | 2019 |
Melanin-Concentrating Hormone (MCH) and MCH-R1 in the Locus Coeruleus May Be Involved in the Regulation of Depressive-Like Behavior.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal | 2018 |
Corticosterone and pyridostigmine/DEET exposure attenuate peripheral cytokine expression: Supporting a dominant role for neuroinflammation in a mouse model of Gulf War Illness.
Topics: Animals; Cholinesterase Inhibitors; Corticosterone; Cytokines; DEET; Disease Models, Animal; Gene Ex | 2019 |
Duration dependent effect of chronic stress on primary and secondary lymphoid organs and their reversibility in rats.
Topics: Animals; Apoptosis; Cells, Cultured; Chronic Disease; Corticosterone; Disease Models, Animal; Humans | 2019 |
Role of corticosterone in anxiety- and depressive-like behavior and HPA regulation following prenatal alcohol exposure.
Topics: Animals; Anxiety Disorders; Central Nervous System Depressants; Corticosterone; Depressive Disorder; | 2019 |
Adrenal hormones mediate disease tolerance in malaria.
Topics: Adrenal Glands; Adrenalectomy; Animals; Blood Glucose; Brain; Corticosterone; Cytokines; Dexamethaso | 2018 |
Cocaine and cocaine expectancy increase growth hormone, ghrelin, GLP-1, IGF-1, adiponectin, and corticosterone while decreasing leptin, insulin, GIP, and prolactin.
Topics: Adiponectin; Animals; Cocaine; Cocaine-Related Disorders; Corticosterone; Disease Models, Animal; Dr | 2019 |
Differences in serum steroid hormones concentrations in Spontaneously Hypertensive Rats (SHR) - an animal model of Attention-Deficit/Hyperactivity Disorder (ADHD).
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Biomarkers; Corticosterone; Disease Models, | 2019 |
Chronic histamine 3 receptor antagonism alleviates depression like conditions in mice via modulation of brain-derived neurotrophic factor and hypothalamus-pituitary adrenal axis.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain; Brain-Derived Neurotrophic Factor; Corticos | 2019 |
Anxiolytic effects of γ-oryzanol in chronically- stressed mice are related to monoamine levels in the brain.
Topics: Amygdala; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Body Weight; Cerebral Cortex; Cor | 2019 |
Diminished responses to monoaminergic antidepressants but not ketamine in a mouse model for neuropsychiatric lupus.
Topics: Animals; Antidepressive Agents; Corticosterone; Depressive Disorder, Treatment-Resistant; Disease Mo | 2019 |
On the role of corticosterone in behavioral disorders, microbiota composition alteration and neuroimmune response in adult male mice subjected to maternal separation stress.
Topics: Animals; Animals, Newborn; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Corticos | 2019 |
Effects of Oxytocin on Fear Memory and Neuroinflammation in a Rodent Model of Posttraumatic Stress Disorder.
Topics: Animals; Brain; Corticosterone; Cytokines; Disease Models, Animal; Extinction, Psychological; Fear; | 2018 |
Antidepressant effect of helicid in chronic unpredictable mild stress model in rats.
Topics: Animals; Antidepressive Agents; Benzaldehydes; Brain-Derived Neurotrophic Factor; Corticosterone; De | 2019 |
Gestational Stress Augments Postpartum β-Amyloid Pathology and Cognitive Decline in a Mouse Model of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cognitive Dysfunction; Corticosterone; Dis | 2019 |
Antidepressant-Like and Neuroprotective Effects of Ethanol Extract from the Root Bark of
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain; Brain-Derived Neurotrophic Factor; Cell Sur | 2018 |
Effects of escitalopram and ibuprofen on a depression-like phenotype induced by chronic stress in rats.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Citalopram; Cor | 2019 |
Role of corticosterone in altered neurobehavioral responses to acute stress in a model of compromised hypothalamic-pituitary-adrenal axis function.
Topics: Animals; Anxiety; Anxiety Disorders; Corticosterone; Depression; Depressive Disorder; Disease Models | 2019 |
Memory generalization after one-trial contextual fear conditioning: Effects of sex and neuropeptide S receptor deficiency.
Topics: Animals; Anxiety; Conditioning, Psychological; Corticosterone; Disease Models, Animal; Electroshock; | 2019 |
Antidepressive Effects of Taraxacum Officinale in a Mouse Model of Depression Are Due to Inhibition of Corticosterone Levels and Modulation of Mitogen-Activated Protein Kinase Phosphatase-1 (Mkp-1) and Brain-Derived Neurotrophic Factor (Bdnf) Expression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corticosterone; | 2019 |
Antidepressant activities of escitalopram and blonanserin on prenatal and adolescent combined stress-induced depression model: Possible role of neurotrophic mechanism change in serum and nucleus accumbens.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Citalopram; Cor | 2019 |
Antidepressant-like activities of live and heat-killed Lactobacillus paracasei PS23 in chronic corticosterone-treated mice and possible mechanisms.
Topics: Animals; Antidepressive Agents; Anxiety; Anxiety Disorders; Behavior, Animal; Brain; Corticosterone; | 2019 |
Inborn vs. acquired anxiety in cross-breeding and cross-fostering HAB/LAB mice bred for extremes in anxiety-related behavior.
Topics: Animals; Anxiety; Behavior, Animal; Breeding; Corticosterone; Disease Models, Animal; Female; Gene-E | 2019 |
DNA methylation of the Tacr2 gene in a CUMS model of depression.
Topics: Animals; Body Weight; Corticosterone; Corticotropin-Releasing Hormone; Depression; Depressive Disord | 2019 |
PINK1 deficiency is associated with increased deficits of adult hippocampal neurogenesis and lowers the threshold for stress-induced depression in mice.
Topics: Animals; Anxiety; Anxiety Disorders; Behavior, Animal; Cell Differentiation; Cell Proliferation; Cor | 2019 |
Post-Stress Fructose and Glucose Ingestion Exhibit Dissociable Behavioral and Physiological Effects.
Topics: Animals; Behavior, Animal; Blood Glucose; Corticosterone; Disease Models, Animal; Eating; Fructose; | 2019 |
Ketamine improved depressive-like behaviors via hippocampal glucocorticoid receptor in chronic stress induced- susceptible mice.
Topics: Animals; Anxiety; Corticosterone; Depression; Depressive Disorder; Disease Models, Animal; Gene Expr | 2019 |
Baicalein improves cognitive deficits and hippocampus impairments in temporal lobe epilepsy rats.
Topics: Animals; Brain; Cofilin 1; Cognition; Cognition Disorders; Cognitive Dysfunction; Corticosterone; Di | 2019 |
The impact of early-life stress on corticosteroid carrier protein levels and 11β-hydroxysteroid dehydrogenase 1 expression in adolescent rats.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Brain; Corticosterone; Disease Models, Animal; | 2019 |
Developmental outcomes after gestational antidepressant treatment with sertraline and its discontinuation in an animal model of maternal depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; Depressive Disorder; D | 2019 |
Faecalibacterium prausnitzii (ATCC 27766) has preventive and therapeutic effects on chronic unpredictable mild stress-induced depression-like and anxiety-like behavior in rats.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Behavior, Animal; Bone Density; Brain; Bra | 2019 |
Protocatechuic acid attenuate depressive-like behavior in olfactory bulbectomized rat model: behavioral and neurobiochemical investigations.
Topics: Animals; Antidepressive Agents; Antioxidants; Behavior, Animal; Corticosterone; Depression; Disease | 2019 |
Early weaning increases anxiety via brain-derived neurotrophic factor signaling in the mouse prefrontal cortex.
Topics: Animals; Animals, Newborn; Anxiety; Brain-Derived Neurotrophic Factor; Corticosterone; Disease Model | 2019 |
Effects of corticosterone on the expression of mature brain-derived neurotrophic factor (mBDNF) and proBDNF in the hippocampal dentate gyrus.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Corticosterone; Dentate Gyrus; De | 2019 |
Two-hit model of postintensive care syndrome induced by lipopolysaccharide challenge and subsequent chronic unpredictable stress in mice.
Topics: Animals; Anxiety; Chronic Disease; Cognition Disorders; Corticosterone; Critical Care; Critical Illn | 2019 |
New neurons restore structural and behavioral abnormalities in a rat model of PTSD.
Topics: Animals; Anxiety; Behavior, Animal; CA1 Region, Hippocampal; Cell Proliferation; Corticosterone; Den | 2019 |
Effects of a selanylimidazopyridine on the acute restraint stress-induced depressive- and anxiety-like behaviors and biological changes in mice.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Brain-Derived Neurot | 2019 |
Topics: Animals; Animals, Newborn; Anxiety; Corticosterone; Cytokines; Depression; Disease Models, Animal; F | 2019 |
Quercetin mitigates anxiety-like behavior and normalizes hypothalamus-pituitary-adrenal axis function in a mouse model of mild traumatic brain injury.
Topics: Adrenocorticotropic Hormone; Animals; Anxiety; Anxiety Disorders; Brain Concussion; Corticosterone; | 2019 |
The blockade of corticotropin-releasing factor 1 receptor attenuates anxiety-related symptoms and hypothalamus-pituitary-adrenal axis reactivity in mice with mild traumatic brain injury.
Topics: Adrenocorticotropic Hormone; Animals; Anxiety; Anxiety Disorders; Brain Concussion; Corticosterone; | 2019 |
The Antidepressant-like Effect of Flavonoids from
Topics: Animals; Antidepressive Agents; Apoptosis Regulatory Proteins; Behavior, Animal; Body Weight; Chroma | 2019 |
Reversal effect of Riparin IV in depression and anxiety caused by corticosterone chronic administration in mice.
Topics: Amides; Anhedonia; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; B | 2019 |
Low-Intensity Exercise in Mice Is Sufficient to Protect Retinal Function During Light-Induced Retinal Degeneration.
Topics: Animals; Cathepsin B; Complement C1q; Corticosterone; Disease Models, Animal; Electroretinography; M | 2019 |
Behavioral and biological markers for predicting compulsive-like drinking in schedule-induced polydipsia.
Topics: Animals; Biomarkers; Blood Glucose; Compulsive Behavior; Conditioning, Operant; Corticosterone; Dise | 2019 |
Comparative pharmacokinetic study of four major bioactive components after oral administration of Zhi-Zi-Hou-Po decoction in normal and corticosterone-induced depressive rats.
Topics: Administration, Oral; Animals; Biphenyl Compounds; Corticosterone; Depression; Disease Models, Anima | 2019 |
Heat stress, Eimeria spp. and C. perfringens infections alone or in combination modify gut Th1/Th2 cytokine balance and avian necrotic enteritis pathogenesis.
Topics: Animals; Chickens; Clostridium Infections; Clostridium perfringens; Coccidiosis; Coinfection; Cortic | 2019 |
Sustained rescue of prefrontal circuit dysfunction by antidepressant-induced spine formation.
Topics: Animals; Antidepressive Agents; Corticosterone; Dendritic Spines; Depressive Disorder; Disease Model | 2019 |
Affective profiling for anxiety-like behavior in a rodent model of mTBI.
Topics: Amygdala; Animals; Anxiety; Blast Injuries; Brain Concussion; Brain Injuries; Comorbidity; Corticost | 2019 |
The Chinese Herbal Formula PAPZ Ameliorates Behavioral Abnormalities in Depressive Mice.
Topics: Angelica sinensis; Animals; Antidepressive Agents; Antioxidants; Behavior, Animal; Brain-Derived Neu | 2019 |
Cholestasis-associated glucocorticoid overexposure does not increase atherogenesis.
Topics: 1-Naphthylisothiocyanate; Animals; Apolipoproteins E; Atherosclerosis; Cholestasis; Cholesterol; Cor | 2019 |
High dose of dexamethasone protects against EAE-induced motor deficits but impairs learning/memory in C57BL/6 mice.
Topics: Animals; Anti-Inflammatory Agents; Corticosterone; Dexamethasone; Disease Models, Animal; Encephalom | 2019 |
Noise-induced hearing loss alters hippocampal glucocorticoid receptor expression in rats.
Topics: Animals; Corticosterone; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Feedback, | 2019 |
The anxiolytic-like effects of ginsenoside Rg2 on an animal model of PTSD.
Topics: Adrenocorticotropic Hormone; Animals; Anti-Anxiety Agents; Antidepressive Agents; Corticosterone; Co | 2019 |
Chronic hypercortisolism causes more persistent visceral adiposity than HFD-induced obesity.
Topics: Adipose Tissue; Adiposity; Animals; Anti-Inflammatory Agents; Body Weight; Corticosterone; Cushing S | 2019 |
Effect of chronic corticosterone treatment on expression and distribution of serotonin 5-HT7 receptors in rat adrenal glands.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Corticosterone; Disease Models, Animal; Humans | 2019 |
Late glucocorticoid receptor antagonism changes the outcome of adult life stress.
Topics: Animals; Brain; Corticosterone; Disease Models, Animal; Exploratory Behavior; Extinction, Psychologi | 2019 |
Individual variability in behavior and functional networks predicts vulnerability using an animal model of PTSD.
Topics: Animals; Anxiety; Avoidance Learning; Behavior, Animal; Brain; Corticosterone; Disease Models, Anima | 2019 |
A Chronic Immobilization Stress Protocol for Inducing Depression-Like Behavior in Mice.
Topics: Animals; Behavior, Animal; Corticosterone; Depression; Diet; Disease Models, Animal; Glutamine; Male | 2019 |
"Comfort-foods" chronic intake has different behavioral and neurobiological effects in male rats exposed or not to early-life stress.
Topics: Adiposity; Adverse Childhood Experiences; Animals; Animals, Newborn; Anxiety; Corticosterone; Diseas | 2020 |
Depression comorbid with hyperalgesia: Different roles of neuroinflammation induced by chronic stress and hypercortisolism.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Depression; Disease Models, Animal; Hippocampu | 2019 |
UPLC-QTOF/MS-based metabolomics reveals the mechanism of chronic unpredictable mild stress-induced hypertension in rats.
Topics: Amino Acids; Animals; Blood Pressure; Chromatography, High Pressure Liquid; Chronic Disease; Cortico | 2019 |
Sex-dependent effects of early unstable post-natal environment on response to positive and negative stimuli in adult mice.
Topics: Anhedonia; Animals; Behavior, Animal; Brain; Cocaine; Corticosterone; Disease Models, Animal; Dopami | 2019 |
Esketamine and rapastinel, but not imipramine, have antidepressant-like effect in a treatment-resistant animal model of depression.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depre | 2019 |
Fighting Females: Neural and Behavioral Consequences of Social Defeat Stress in Female Mice.
Topics: Aggression; Animals; Behavior, Animal; Brain; Corticosterone; Disease Models, Animal; Female; Genes, | 2019 |
Short-term sleep fragmentation enhances anxiety-related behavior: The role of hormonal alterations.
Topics: Animals; Anxiety; Behavior, Animal; Corticosterone; Disease Models, Animal; Estradiol; Exercise Test | 2019 |
Diminished ovarian reserve induced by chronic unpredictable stress in C57BL/6 mice.
Topics: Animals; Anti-Mullerian Hormone; Chronic Disease; Corpus Luteum; Corticosterone; Disease Models, Ani | 2020 |
Studies on the anti-fatigue activities of Irpex lacteus polysaccharide-enriched extract in mouse model.
Topics: Adenosine Triphosphate; Adrenocorticotropic Hormone; AMP-Activated Protein Kinases; Animals; Behavio | 2019 |
Stressor during Early Adolescence in Hyperreactive Female Wistar Kyoto Rats Induces a 'Double Hit' Manifested by Variation in Neurobehaviors and Brain Monoamines.
Topics: Animals; Behavior, Animal; Brain; Corticosterone; Disease Models, Animal; Dopamine; Female; Helpless | 2019 |
Edaravone presents antidepressant-like activity in corticosterone model of depression in mice with possible role of Fkbp5, Comt, Adora1 and Slc6a15 genes.
Topics: Amino Acid Transport Systems, Neutral; Animals; Antidepressive Agents; Behavior, Animal; Catechol O- | 2019 |
Corticosterone-Mediated Body Weight Loss Is an Important Catabolic Process for Poststroke Immunity and Survival.
Topics: Animals; Brain; Corticosterone; Disease Models, Animal; Infarction, Middle Cerebral Artery; Macropha | 2019 |
Antidepressant-like effects of 20(S)-protopanaxadiol in a mouse model of chronic social defeat stress and the related mechanisms.
Topics: Animals; Antidepressive Agents; Chronic Disease; Corticosterone; Depression; Disease Models, Animal; | 2019 |
Therapeutic glucocorticoids prevent bone loss but drive muscle wasting when administered in chronic polyarthritis.
Topics: Animals; Arthritis; Biopsy; Bone Resorption; Cells, Cultured; Chronic Disease; Corticosterone; Disea | 2019 |
The effect of fluoxetine on astrocyte autophagy flux and injured mitochondria clearance in a mouse model of depression.
Topics: Animals; Antidepressive Agents; Astrocytes; Autophagosomes; Autophagy; Corticosterone; Depression; D | 2019 |
Chronic fluoxetine reverses the effects of chronic corticosterone treatment on α
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic Neurons; A | 2019 |
Memory impairment induced by different types of prolonged stress is dependent on the phase of the estrous cycle in female rats.
Topics: Animals; Corticosterone; Disease Models, Animal; Estradiol; Estrous Cycle; Female; Memory Disorders; | 2019 |
Stress- and antidepressant treatment-induced modifications of 5-HT₇ receptor functions in the rat brain.
Topics: Animals; Antidepressive Agents; CA1 Region, Hippocampal; Cerebral Cortex; Corticosterone; Disease Mo | 2012 |
Effect of co-treatment with fluoxetine or mirtazapine and risperidone on the active behaviors and plasma corticosterone concentration in rats subjected to the forced swim test.
Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antipsychotic A | 2012 |
Prenatal exposure to escitalopram and/or stress in rats: a prenatal stress model of maternal depression and its treatment.
Topics: Animals; Citalopram; Corticosterone; Darkness; Depression; Disease Models, Animal; Female; Infusion | 2013 |
G-protein-coupled receptor kinase-5 mediates inflammation but does not regulate cellular infiltration or bacterial load in a polymicrobial sepsis model in mice.
Topics: Animals; Apoptosis; Bacterial Load; Cecum; Cell Movement; Cells, Cultured; Corticosterone; Disease M | 2013 |
The role of Akt/FoxO3a in the protective effect of venlafaxine against corticosterone-induced cell death in PC12 cells.
Topics: Animals; Antidepressive Agents, Second-Generation; Blotting, Western; Cell Death; Corticosterone; Cy | 2013 |
Antipurinergic therapy corrects the autism-like features in the poly(IC) mouse model.
Topics: Animals; Autistic Disorder; Behavior, Animal; Brain; Calcium-Calmodulin-Dependent Protein Kinase Typ | 2013 |
Antidepressant-like effect of macranthol isolated from Illicium dunnianum tutch in mice.
Topics: Alkenes; Animals; Antidepressive Agents; Corticosterone; Depression; Disease Models, Animal; Dose-Re | 2013 |
Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-β.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Animals, Newborn; Cells, Cultured; C | 2013 |
Sensitization of restraint-induced corticosterone secretion after chronic restraint in rats: involvement of 5-HT₇ receptors.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Corticosterone; Disease Models, Animal; Hypoth | 2013 |
Glucocorticoid-induced hypertension and cardiac injury: effects of mineralocorticoid and glucocorticoid receptor antagonism.
Topics: Animals; Atrophy; Blood Pressure; Corticosterone; Disease Models, Animal; Fibrosis; Heart Diseases; | 2013 |
Effects of ketamine and LY341495 on the depressive-like behavior of repeated corticosterone-injected rats.
Topics: Amino Acids; Animals; Corticosterone; Depressive Disorder, Treatment-Resistant; Disease Models, Anim | 2013 |
Acute stress enhances adult rat hippocampal neurogenesis and activation of newborn neurons via secreted astrocytic FGF2.
Topics: Acute Disease; Adaptation, Physiological; Adaptation, Psychological; Age Factors; Animals; Animals, | 2013 |
The progressive development of depression-like behavior in corticosterone-treated rats is paralleled by slowed granule cell maturation and decreased reelin expression in the adult dentate gyrus.
Topics: Animals; Behavior, Animal; Cell Adhesion Molecules, Neuronal; Cell Differentiation; Corticosterone; | 2013 |
Suppression of neuroinflammatory and apoptotic signaling cascade by curcumin alone and in combination with piperine in rat model of olfactory bulbectomy induced depression.
Topics: Alkaloids; Animals; Apoptosis; Benzodioxoles; Brain; Brain-Derived Neurotrophic Factor; Caspase 3; C | 2013 |
Glucocorticoid signaling in myeloid cells worsens acute CNS injury and inflammation.
Topics: Analysis of Variance; Animals; Brain Infarction; Brain Injuries; Brain-Derived Neurotrophic Factor; | 2013 |
Effects of MK-801 and amphetamine treatments on allergic lung inflammatory response in mice.
Topics: Amphetamine; Animals; Bone Marrow Cells; Bronchoalveolar Lavage Fluid; Cell Degranulation; Chemotaxi | 2013 |
Chronic unpredictable mild stress alters an anxiety-related defensive response, Fos immunoreactivity and hippocampal adult neurogenesis.
Topics: Analysis of Variance; Animals; Anxiety; Avoidance Learning; Corticosterone; Disease Models, Animal; | 2013 |
Myelophil attenuates brain oxidative damage by modulating the hypothalamus-pituitary-adrenal (HPA) axis in a chronic cold-stress mouse model.
Topics: Animals; Apoptosis; Ascorbic Acid; Brain Injuries; Caspase 3; Caspase 7; Corticosterone; Disease Mod | 2013 |
The effects of brain serotonin deficiency on behavioural disinhibition and anxiety-like behaviour following mild early life stress.
Topics: Amygdala; Animals; Anxiety; Anxiety, Separation; Behavior, Animal; Brain; Corticosterone; Disease Mo | 2013 |
Paraventricular hypothalamic regulation of trigeminovascular mechanisms involved in headaches.
Topics: Action Potentials; Animals; Biotin; Corticosterone; Dextrans; Disease Models, Animal; GABA Antagonis | 2013 |
Dendritic development of hippocampal CA1 pyramidal cells in a neonatal hypoxia-ischemia injury model.
Topics: Age Factors; Animals; Animals, Newborn; CA1 Region, Hippocampal; Corticosterone; Dendrites; Disease | 2013 |
Disruption of circadian rhythms due to chronic constant light leads to depressive and anxiety-like behaviors in the rat.
Topics: Analysis of Variance; Animals; Anxiety; Body Weight; Cell Count; Chronobiology Disorders; Corticoste | 2013 |
Parents' adulthood stress induces behavioral and hormonal alterations in male rat offspring.
Topics: Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Birth Weight; Corticosterone; Dis | 2013 |
Epithelial-specific deletion of 11β-HSD2 hinders Apcmin/+ mouse tumorigenesis.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adenoma; Animals; Carcinogenesis; Cell Cycle; Cell Line | 2013 |
Protective effects of luteolin on cognitive impairments induced by psychological stress in mice.
Topics: Animals; Catalase; Cognition Disorders; Corticosterone; Disease Models, Animal; Dopamine; Dose-Respo | 2013 |
Exogenous glucocorticoids and a high-fat diet cause severe hyperglycemia and hyperinsulinemia and limit islet glucose responsiveness in young male Sprague-Dawley rats.
Topics: Animals; Circadian Rhythm; Corticosterone; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models | 2013 |
Tooth loss induces memory impairment and neuronal cell loss in APP transgenic mice.
Topics: Adaptation, Ocular; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Avoidance Learni | 2013 |
Fear extinction and acute stress reactivity reveal a role of LPA(1) receptor in regulating emotional-like behaviors.
Topics: Amygdala; Animals; Conditioning, Classical; Corticosterone; Cues; Disease Models, Animal; Emotions; | 2014 |
Protective effects of sivelestat in a caerulein-induced rat acute pancreatitis model.
Topics: Amylases; Animals; Antioxidants; Ceruletide; Corticosterone; Disease Models, Animal; Glycine; Inflam | 2013 |
Depression-like behavior in subclinical hypothyroidism rat induced by hemi-thyroid electrocauterization.
Topics: Adrenal Cortex; Animals; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Elect | 2014 |
Differential impact of a complex environment on positive affect in an animal model of individual differences in emotionality.
Topics: Affect; Animals; Anxiety; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Envi | 2013 |
The effect of acute swim stress and training in the water maze on hippocampal synaptic activity as well as plasticity in the dentate gyrus of freely moving rats: revisiting swim-induced LTP reinforcement.
Topics: Analysis of Variance; Animals; Corticosterone; Disease Models, Animal; Enzyme-Linked Immunosorbent A | 2013 |
Orcinol glucoside produces antidepressant effects by blocking the behavioural and neuronal deficits caused by chronic stress.
Topics: Animals; Antidepressive Agents; Chronic Disease; Corticosterone; Corticotropin-Releasing Hormone; De | 2014 |
Systematic correlation between spine plasticity and the anxiety/depression-like phenotype induced by corticosterone in mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; CA1 Region, Hippocampal; Corticosterone; Dendritic | 2013 |
Effects of palmitoylethanolamide and luteolin in an animal model of anxiety/depression.
Topics: Amides; Animals; Antidepressive Agents; Anxiety; Apoptosis; Behavior, Animal; Brain; Brain-Derived N | 2013 |
Chronic mild sleep restriction accentuates contextual memory impairments, and accumulations of cortical Aβ and pTau in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of Variance; Anim | 2013 |
A high-salt diet further impairs age-associated declines in cognitive, behavioral, and cardiovascular functions in male Fischer brown Norway rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aging; Animals; Anxiety; Blood Pressure; Corticosterone; Deoxyguanosine | 2013 |
Central 5-alpha reduction of testosterone is required for testosterone's inhibition of the hypothalamo-pituitary-adrenal axis response to restraint stress in adult male rats.
Topics: 5-alpha Reductase Inhibitors; Adrenocorticotropic Hormone; Animals; Corticosterone; Dihydrotestoster | 2013 |
CB1 receptor mediates the effects of glucocorticoids on AMPK activity in the hypothalamus.
Topics: Adipose Tissue; AMP-Activated Protein Kinases; Animals; Corticosterone; Cushing Syndrome; Disease Mo | 2013 |
Risperidone ameliorates post-traumatic stress disorder-like symptoms in modified stress re-stress model.
Topics: Animals; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Brain; Corticosterone; Dise | 2013 |
Prenatal transport stress, postnatal maternal behavior, and offspring sex differentially affect seizure susceptibility in young rats.
Topics: Animals; Animals, Newborn; Brain; Corticosterone; Disease Models, Animal; Disease Susceptibility; Ep | 2013 |
Autonomic dysreflexia causes chronic immune suppression after spinal cord injury.
Topics: Adrenergic beta-2 Receptor Antagonists; Animals; Antigens, CD; Autonomic Dysreflexia; Blood Pressure | 2013 |
Expression of the glucocorticoid receptor is decreased in experimental Staphylococcus aureus sepsis.
Topics: Analysis of Variance; Animals; Bacteremia; Bacterial Load; Cell Nucleus; Corticosterone; Cytokines; | 2013 |
Zinc deficiency alters responsiveness to antidepressant drugs in mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; Diet; Disease Models, | 2013 |
An animal model of stress-induced cardiomyopathy utilizing the social defeat paradigm.
Topics: Animals; Behavior, Animal; Body Weight; Cardiomyopathies; Corticosterone; Data Interpretation, Stati | 2013 |
Anxiety- and depression-like behavior are correlated with leptin and leptin receptor expression in prefrontal cortex of streptozotocin-induced diabetic rats.
Topics: Animals; Anxiety; Behavior, Animal; Corticosterone; Depression; Diabetes Mellitus, Experimental; Dis | 2014 |
Sirtuin activity in dentate gyrus contributes to chronic stress-induced behavior and extracellular signal-regulated protein kinases 1 and 2 cascade changes in the hippocampus.
Topics: Animals; Chromatin Immunoprecipitation; Chronic Disease; Corticosterone; Dentate Gyrus; Disease Mode | 2013 |
Influence of a probiotic lactobacillus strain on the intestinal ecosystem in a stress model mouse.
Topics: Animals; CD11 Antigens; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Corticosterone; Dise | 2014 |
Transient downregulation of Dab1 protein levels during development leads to behavioral and structural deficits: relevance for psychiatric disorders.
Topics: Animals; Animals, Newborn; Antipsychotic Agents; beta-Galactosidase; Brain; Clozapine; Corticosteron | 2014 |
Corticosteroid-binding globulin contributes to the neuroendocrine phenotype of mice selected for extremes in stress reactivity.
Topics: Adaptation, Psychological; Animals; Behavior, Animal; Corticosterone; Disease Models, Animal; Geneti | 2013 |
Hydrocortisone reduces the beneficial effects of toll-like receptor 2 deficiency on survival in a mouse model of polymicrobial sepsis.
Topics: Animals; Corticosterone; Disease Models, Animal; Feedback, Physiological; Hydrocortisone; Hypothalam | 2013 |
Susceptibility to life-threatening ventricular arrhythmias in an animal model of paradoxical sleep deprivation.
Topics: Aconitine; Animals; Blood Pressure; Corticosterone; Disease Models, Animal; Electrocardiography; Hea | 2013 |
Female rats exposed to stress and alcohol show impaired memory and increased depressive-like behaviors.
Topics: Alcohols; Analysis of Variance; Animals; Body Weight; Corticosterone; Depression; Disease Models, An | 2014 |
A new stress model, a scream sound, alters learning and monoamine levels in rat brain.
Topics: Adrenal Glands; Animals; Biogenic Monoamines; Body Weight; Brain; Corticosterone; Disease Models, An | 2014 |
A ghrelin-growth hormone axis drives stress-induced vulnerability to enhanced fear.
Topics: Amygdala; Animals; Chronic Disease; Corticosterone; Corticotropin-Releasing Hormone; Disease Models, | 2014 |
Estradiol decreases rat depressive behavior by estrogen receptor beta but not alpha: no correlation with plasma corticosterone.
Topics: Animals; Corticosterone; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Estra | 2014 |
Glucocorticoids downregulate systemic nitric oxide synthesis and counteract overexpression of hepatic heme oxygenase-1 during endotoxin tolerance.
Topics: Adrenalectomy; Animals; Corticosterone; Dexamethasone; Disease Models, Animal; Down-Regulation; Endo | 2013 |
Effects of chronic jet lag on the central and peripheral circadian clocks in CBA/N mice.
Topics: Animals; Behavior, Animal; Chronic Disease; Circadian Rhythm; Circadian Rhythm Signaling Peptides an | 2014 |
Hypothermia after chronic mild stress exposure in rats with a history of postnatal maternal separations.
Topics: Age Factors; Animals; Animals, Newborn; Anxiety, Separation; Behavior, Animal; Biomarkers; Body Temp | 2014 |
Disruption of social bonds induces behavioral and physiological dysregulation in male and female prairie voles.
Topics: Adrenocorticotropic Hormone; Animals; Arvicolinae; Atenolol; Atropine; Autonomic Nervous System; Ber | 2014 |
Effects of Papaver rhoeas (L.) extract on formalin-induced pain and inflammation in mice.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Corticosterone; Disease Models, Animal; Dose-Response | 2012 |
Resveratrol prevents impaired cognition induced by chronic unpredictable mild stress in rats.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cognition Disorders; Corticosterone; Cyclic AMP Response | 2014 |
Essential amino acid enriched high-protein enteral nutrition modulates insulin-like growth factor-1 system function in a rat model of trauma-hemorrhagic shock.
Topics: Amino Acids, Essential; Animals; Blotting, Western; Corticosterone; Dietary Proteins; Disease Models | 2013 |
Immediate ketamine treatment does not prevent posttraumatic stress responses in an animal model for PTSD.
Topics: Acoustic Stimulation; Animals; Anti-Anxiety Agents; Corticosterone; Dexamethasone; Disease Models, A | 2014 |
Leukocytosis and enhanced susceptibility to endotoxemia but not atherosclerosis in adrenalectomized APOE knockout mice.
Topics: Adrenalectomy; Animals; Apolipoproteins E; Atherosclerosis; Corticosterone; Disease Models, Animal; | 2013 |
Short-term psychosocial stress protects photoreceptors from damage via corticosterone-mediated activation of the AKT pathway.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Corticosterone; Disease Models, Animal; Endothelin-2; | 2014 |
Effects of dominant/subordinate social status on formalin-induced pain and changes in serum proinflammatory cytokine concentrations in mice.
Topics: Animals; Body Weight; Corticosterone; Disease Models, Animal; Dominance-Subordination; Formaldehyde; | 2013 |
Rapid anxiolytic effects of a 5-HT₄ receptor agonist are mediated by a neurogenesis-independent mechanism.
Topics: Aniline Compounds; Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Anxiety; | 2014 |
An N-ethyl-N-nitrosourea induced corticotropin-releasing hormone promoter mutation provides a mouse model for endogenous glucocorticoid excess.
Topics: Animals; Body Composition; Bone and Bones; Calcium; Cell Line; Chromosome Mapping; Corticosterone; C | 2014 |
An organoselenium compound improves behavioral, endocrinal and neurochemical changes induced by corticosterone in mice.
Topics: Adrenocorticotropic Hormone; Animals; Anxiety; Behavior, Animal; Corticosterone; Depression; Disease | 2014 |
Behavioral and neurochemical effects of dietary methyl donor deficiency combined with unpredictable chronic mild stress in rats.
Topics: Analysis of Variance; Animals; Biogenic Amines; Brain; Choline Deficiency; Chronic Disease; Corticos | 2014 |
Hippocampal gene expression changes underlying stress sensitization and recovery.
Topics: Acute Disease; Animals; Anxiety; Chronic Disease; Corticosterone; Disease Models, Animal; Gene Expre | 2014 |
Melatonin improves outcomes of heatstroke in mice by reducing brain inflammation and oxidative damage and multiple organ dysfunction.
Topics: Adrenocorticotropic Hormone; Animals; Antioxidants; Corticosterone; Disease Models, Animal; Glutathi | 2013 |
Depression-like behaviors in mice subjected to co-treatment of high-fat diet and corticosterone are ameliorated by AICAR and exercise.
Topics: Aminoimidazole Carboxamide; Animals; Corticosterone; Depression; Depressive Disorder; Diet, High-Fat | 2014 |
Tumor necrosis factor-alpha during neonatal brain development affects anxiety- and depression-related behaviors in adult male and female mice.
Topics: Animals; Animals, Newborn; Anxiety; Body Weight; Brain; Corticosterone; Cytokines; Dark Adaptation; | 2014 |
Influence of chronic stress on brain corticosteroid receptors and HPA axis activity.
Topics: Adrenocorticotropic Hormone; Animals; Chronic Disease; Corticosterone; Disease Models, Animal; Habit | 2013 |
Metabolic, behavioral, and reproductive effects of vertical sleeve gastrectomy in an obese rat model of polycystic ovary syndrome.
Topics: Adrenocorticotropic Hormone; Animals; Body Weight; Corticosterone; Disease Models, Animal; Female; G | 2014 |
Aquaporin-4 knockout exacerbates corticosterone-induced depression by inhibiting astrocyte function and hippocampal neurogenesis.
Topics: Animals; Aquaporin 4; Astrocytes; Cell Death; Cells, Cultured; Corticosterone; Depressive Disorder; | 2014 |
New knockout model confirms a role for androgen receptors in regulating anxiety-like behaviors and HPA response in mice.
Topics: Androgen-Insensitivity Syndrome; Animals; Anxiety; Behavior, Animal; Corticosterone; Disease Models, | 2014 |
Chronic unpredictable mild stress impairs erythrocyte immune function and changes T-lymphocyte subsets in a rat model of stress-induced depression.
Topics: Animals; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Drinking; Erythrocyte | 2014 |
Dentin hypersensitivity induces anxiety and increases corticosterone serum levels in rats.
Topics: Adrenal Glands; Animals; Anxiety; Behavior, Animal; Cold Temperature; Corticosterone; Dentin; Dentin | 2014 |
Hippocampal biomarkers of fear memory in an animal model of generalized anxiety disorder.
Topics: Animals; Anxiety Disorders; Avoidance Learning; Biomarkers; Brain-Derived Neurotrophic Factor; Corti | 2014 |
Inhibition of stress-induced hepatic tryptophan 2,3-dioxygenase exhibits antidepressant activity in an animal model of depressive behaviour.
Topics: Allopurinol; Animals; Antidepressive Agents; Cerebral Cortex; Chronic Disease; Corticosterone; Depre | 2014 |
Pitx3 deficient mice as a genetic animal model of co-morbid depressive disorder and parkinsonism.
Topics: Anhedonia; Animals; Antidepressive Agents; Brain; Comorbidity; Corticosterone; Depressive Disorder; | 2014 |
Mechanical allodynia induced by traumatic brain injury is independent of restraint stress.
Topics: Animals; Brain Injuries; Corticosterone; Disease Models, Animal; Face; Forelimb; Functional Laterali | 2014 |
Inhibiting 11β-hydroxysteroid dehydrogenase type 1 prevents stress effects on hippocampal synaptic plasticity and impairs contextual fear conditioning.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Acoustic Stimulation; Analysis of Variance; Animals; Co | 2014 |
Hydroalcoholic extract of Rosemary (Rosmarinus officinalis L.) and its constituent carnosol inhibit formalin-induced pain and inflammation in mice.
Topics: Abietanes; Alcohols; Analgesics; Animals; Anti-Inflammatory Agents; Corticosterone; Cyclooxygenase 1 | 2013 |
Sex-dependent and non-monotonic enhancement and unmasking of methylmercury neurotoxicity by prenatal stress.
Topics: Animals; Animals, Newborn; Brain; Conditioning, Operant; Corticosterone; Disease Models, Animal; Exp | 2014 |
Resveratrol reverses the effects of chronic unpredictable mild stress on behavior, serum corticosterone levels and BDNF expression in rats.
Topics: Animals; Antioxidants; Body Weight; Brain-Derived Neurotrophic Factor; Corticosterone; CREB-Binding | 2014 |
Forced swim stress but not exogenous corticosterone could induce the reinstatement of extinguished morphine conditioned place preference in rats: involvement of glucocorticoid receptors in the basolateral amygdala.
Topics: Amygdala; Analysis of Variance; Animals; Conditioning, Operant; Corticosterone; Disease Models, Anim | 2014 |
Stress and glucocorticoids promote oligodendrogenesis in the adult hippocampus.
Topics: Animals; Cell Differentiation; Cell Proliferation; Cells, Cultured; Corticosterone; Disease Models, | 2014 |
Programming of the hypothalamic-pituitary-adrenal axis by neonatal intermittent hypoxia: effects on adult male ACTH and corticosterone responses are stress specific.
Topics: Adrenocorticotropic Hormone; Animals; Animals, Newborn; Apnea; Circadian Rhythm; Corticosterone; Dis | 2014 |
Chronic stress enhances microglia activation and exacerbates death of nigral dopaminergic neurons under conditions of inflammation.
Topics: Animals; Cell Death; Corticosterone; Cytokines; Disease Models, Animal; Dopaminergic Neurons; Gene E | 2014 |
The selective glucocorticoid receptor modulator CORT108297 restores faulty hippocampal parameters in Wobbler and corticosterone-treated mice.
Topics: Animals; Anti-Inflammatory Agents; Astrocytes; Aza Compounds; Blotting, Western; Cells, Cultured; Co | 2014 |
Panax quinquefolium involves nitric oxide pathway in olfactory bulbectomy rat model.
Topics: Anhedonia; Animals; Arginine; Brain; Corticosterone; Depressive Disorder; Disease Models, Animal; Do | 2014 |
Changes in intestinal glucocorticoid sensitivity in early life shape the risk of epithelial barrier defect in maternal-deprived rats.
Topics: Analysis of Variance; Animals; Azepines; Bacterial Translocation; Colon; Colony-Forming Units Assay; | 2014 |
Evidence supporting the match/mismatch hypothesis of psychiatric disorders.
Topics: Adaptation, Psychological; Adrenal Glands; Amino Acid Transport Systems, Neutral; Animals; Anxiety D | 2014 |
Scavenger receptor BI and high-density lipoprotein regulate thymocyte apoptosis in sepsis.
Topics: Animals; Apoptosis; Cecum; Cells, Cultured; Cholesterol, HDL; Corticosterone; Disease Models, Animal | 2014 |
Induction of intervertebral disc cell apoptosis and degeneration by chronic unpredictable stress.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; bcl-Associated Death Protein; Corticosterone; Diseas | 2014 |
Effects of brief pulse and ultrabrief pulse electroconvulsive stimulation on rodent brain and behaviour in the corticosterone model of depression.
Topics: Adrenal Glands; Analysis of Variance; Animals; Anti-Inflammatory Agents; Body Weight; Brain-Derived | 2014 |
Chewing ameliorates chronic mild stress-induced bone loss in senescence-accelerated mouse (SAMP8), a murine model of senile osteoporosis.
Topics: Adrenal Glands; Aging; Aging, Premature; Animals; Bone Remodeling; Chronic Disease; Corticosterone; | 2014 |
Iptakalim confers an antidepressant effect in a chronic mild stress model of depression through regulating neuro-inflammation and neurogenesis.
Topics: Animals; Antidepressive Agents; Body Weight; Bromodeoxyuridine; Cell Count; Corticosterone; Cytokine | 2014 |
Antidepressant and anxiolytic profiles of newly synthesized arginine vasopressin V1B receptor antagonists: TASP0233278 and TASP0390325.
Topics: Administration, Oral; Animals; Anti-Anxiety Agents; Antidepressive Agents; Antidiuretic Hormone Rece | 2014 |
Moderate treadmill exercise rescues anxiety and depression-like behavior as well as memory impairment in a rat model of posttraumatic stress disorder.
Topics: Anhedonia; Animals; Anxiety Disorders; Corticosterone; Depressive Disorder; Disease Models, Animal; | 2014 |
Short-term thyroid hormone excess affects the heart but does not affect adrenal activity in rats.
Topics: Adrenal Glands; Animals; Blood Pressure; Corticosterone; Disease Models, Animal; Echocardiography; H | 2014 |
Odor cues released by Ehrlich tumor-bearing mice are aversive and induce psychological stress.
Topics: Analysis of Variance; Animals; Carcinoma, Ehrlich Tumor; Catecholamines; Corticosterone; Cues; Disea | 2015 |
The involvement of glucocorticoids in psychological stress-induced exacerbations of experimental allergic asthma.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Corticosterone; Disease Mo | 2014 |
Interplay between diet-induced obesity and chronic stress in mice: potential role of FKBP51.
Topics: Animals; Corticosterone; Diet, High-Fat; Disease Models, Animal; Energy Metabolism; Glucose; Hippoca | 2014 |
Converging translational evidence for the involvement of the serotonin 2A receptor gene in major depressive disorder.
Topics: Adolescent; Adult; Aged; Animals; Anxiety Disorders; Corticosterone; Depressive Disorder, Major; Dis | 2014 |
Sex-specific disruptions in spatial memory and anhedonia in a "two hit" rat model correspond with alterations in hippocampal brain-derived neurotrophic factor expression and signaling.
Topics: Anhedonia; Animals; Anxiety; Brain-Derived Neurotrophic Factor; Corticosterone; Dietary Sucrose; Dis | 2014 |
High stress hormone levels accelerate the onset of memory deficits in male Huntington's disease mice.
Topics: Age of Onset; Animals; Brain-Derived Neurotrophic Factor; Cell Proliferation; Corticosterone; Diseas | 2014 |
Peer pressures: social instability stress in adolescence and social deficits in adulthood in a rodent model.
Topics: Adolescent; Adolescent Development; Adult; Age Factors; Animals; Corticosterone; Disease Models, Ani | 2015 |
Antidepressant-like effects of omega-3 fatty acids in postpartum model of depression in rats.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Cytokines; Depression, Postpartum; | 2014 |
Increased number of orexin/hypocretin neurons with high and prolonged external stress-induced depression.
Topics: Animals; Body Weight; Cell Count; Circadian Rhythm; Corticosterone; Depressive Disorder; Disease Mod | 2014 |
Witnessing traumatic events causes severe behavioral impairments in rats.
Topics: Animals; Anxiety; Corticosterone; Depression; Disease Models, Animal; Dominance-Subordination; Housi | 2014 |
Pycnogenol ameliorates depression-like behavior in repeated corticosterone-induced depression mice model.
Topics: Animals; Antioxidants; Corticosterone; Depression; Depressive Disorder; Disease Models, Animal; Flav | 2014 |
NREM sleep hypersomnia and reduced sleep/wake continuity in a neuroendocrine mouse model of anxiety/depression based on chronic corticosterone administration.
Topics: Animals; Anxiety Disorders; Brain; Corticosterone; Darkness; Depressive Disorder; Disease Models, An | 2014 |
Changes in morphology and function of adrenal cortex in mice fed a high-fat diet.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Animals; Cells, Cultured; Corticosterone; Diet, High-Fat; D | 2015 |
Emodin opposes chronic unpredictable mild stress induced depressive-like behavior in mice by upregulating the levels of hippocampal glucocorticoid receptor and brain-derived neurotrophic factor.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corticosterone; | 2014 |
Selective histone deacetylase-6 inhibition attenuates stress responses and prevents immune organ atrophy in a lethal septic model.
Topics: Adrenocorticotropic Hormone; Animals; Apoptosis; Atrophy; Bone Marrow; Corticosterone; Disease Model | 2014 |
D-serine prevents cognitive deficits induced by acute stress.
Topics: Acute Disease; Animals; Cognition Disorders; Corticosterone; Disease Models, Animal; Glycine; Hippoc | 2014 |
Early life adversity and serotonin transporter gene variation interact at the level of the adrenal gland to affect the adult hypothalamo-pituitary-adrenal axis.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Age Factors; Animals; Corticosterone; Disease Models, A | 2014 |
Stress management affects outcomes in the pathophysiology of an endometriosis model.
Topics: Adaptation, Psychological; Animals; Behavior, Animal; Colon; Corticosterone; Defecation; Disease Mod | 2015 |
Hormonal changes and increased anxiety-like behavior in a perimenopause-animal model induced by 4-vinylcyclohexene diepoxide (VCD) in female rats.
Topics: Animals; Anxiety; Corticosterone; Cyclohexenes; Dihydrotestosterone; Disease Models, Animal; Estradi | 2014 |
Effects of chronic stress on the onset and progression of Huntington's disease in transgenic mice.
Topics: Animals; Corticosterone; Disease Models, Animal; Disease Progression; Female; Humans; Huntingtin Pro | 2014 |
Ethological endophenotypes are altered by elevated stress hormone levels in both Huntington's disease and wildtype mice.
Topics: Animals; Anti-Inflammatory Agents; Corticosterone; Disease Models, Animal; Dose-Response Relationshi | 2014 |
Gonadotropin-releasing hormone agonist selectively augments thymopoiesis and prevents cell apoptosis in LPS induced thymic atrophy model independent of gonadal steroids.
Topics: Animals; Apoptosis; Atrophy; Castration; Corticosterone; Disease Models, Animal; DNA Fragmentation; | 2014 |
Effect of acute swim stress on plasma corticosterone and brain monoamine levels in bidirectionally selected DxH recombinant inbred mouse strains differing in fear recall and extinction.
Topics: Acoustic Stimulation; Acute Disease; Animals; Behavior, Animal; Biogenic Monoamines; Brain; Corticos | 2014 |
Mice selected for extremes in stress reactivity reveal key endophenotypes of major depression: a translational approach.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Animals; Brain; Corticosterone; Corticotro | 2014 |
Glucocorticoids activate cardiac mineralocorticoid receptors in adrenalectomized Dahl salt-sensitive rats.
Topics: Adrenalectomy; Animals; Blood Pressure; Collagen Type I; Collagen Type III; Corticosterone; Disease | 2014 |
Chronic high-fat diet increases acute neuroendocrine stress response independently of prenatal dexamethasone treatment in male rats.
Topics: Animals; Blood Glucose; Corticosterone; Depression; Dexamethasone; Diet, High-Fat; Disease Models, A | 2014 |
Stress-induced activation of the sympathoadrenal system is determined by genetic background in rat models of tauopathy.
Topics: Animals; Corticosterone; Disease Models, Animal; Epinephrine; Genetic Predisposition to Disease; Nor | 2015 |
The antidepressant effects of ginseng total saponins in male C57BL/6N mice by enhancing hippocampal inhibitory phosphorylation of GSK-3β.
Topics: Animals; Antidepressive Agents; Corticosterone; Depression; Disease Models, Animal; Down-Regulation; | 2014 |
Forebrain glucocorticoid receptor gene deletion attenuates behavioral changes and antidepressant responsiveness during chronic stress.
Topics: Anhedonia; Animals; Antidepressive Agents; Chronic Disease; Circadian Rhythm; Corticosterone; Dietar | 2014 |
Chronic social instability stress enhances vulnerability of BDNF response to LPS in the limbic structures of female rats: a protective role of antidepressants.
Topics: Amygdala; Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Corticosterone; Disease | 2014 |
Cytokine and endocrine parameters in mouse chronic social defeat: implications for translational 'cross-domain' modeling of stress-related brain disorders.
Topics: Animals; Corticosterone; Cytokines; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Models, | 2015 |
St. John's Wort increases brain serotonin synthesis by inhibiting hepatic tryptophan 2, 3 dioxygenase activity and its gene expression in stressed rats.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain; Corticosterone; Disease Models, Animal; Enz | 2014 |
Prenatal exposure to noise stress: anxiety, impaired spatial memory, and deteriorated hippocampal plasticity in postnatal life.
Topics: Animals; Anxiety Disorders; Corticosterone; Disease Models, Animal; Excitatory Postsynaptic Potentia | 2015 |
Early-life-stress affects the homeostasis of glutamatergic synapses.
Topics: Animals; Animals, Newborn; Corticosterone; Disease Models, Animal; Female; Glutamic Acid; Homeostasi | 2014 |
Effects of chronic sleep deprivation on the extracellular signal-regulated kinase pathway in the temporomandibular joint of rats.
Topics: Adrenocorticotropic Hormone; Animals; Butadienes; Cartilage, Articular; Corticosterone; Disease Mode | 2014 |
Weight loss by calorie restriction versus bariatric surgery differentially regulates the hypothalamo-pituitary-adrenocortical axis in male rats.
Topics: Animals; Caloric Restriction; Corticosterone; Corticotropin-Releasing Hormone; Diet, High-Fat; Disea | 2014 |
Safety of a nasal vaccine against Streptococcus pneumoniae using heat-killed Lactobacillus casei as adjuvant.
Topics: Adjuvants, Immunologic; Administration, Intranasal; Animals; Bronchoalveolar Lavage Fluid; C-Reactiv | 2015 |
Role of corticosteroid binding globulin in emotional reactivity sex differences in mice.
Topics: Animals; Circadian Rhythm; Corticosterone; Disease Models, Animal; Emotions; Female; Hypothalamo-Hyp | 2014 |
Lipopolysaccharide repeated challenge followed by chronic mild stress protocol introduces a combined model of depression in rats: reversibility by imipramine and pentoxifylline.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Corticosterone; Depression; Disease Mod | 2014 |
Repeated restraint stress-induced atrophy of glutamatergic pyramidal neurons and decreases in glutamatergic efflux in the rat amygdala are prevented by the antidepressant agomelatine.
Topics: Acetamides; Animals; Antidepressive Agents; Atrophy; Basolateral Nuclear Complex; Corticosterone; De | 2015 |
Effects of N-acetylcysteine and imipramine in a model of acute rhythm disruption in BALB/c mice.
Topics: Acetylcysteine; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Circadian Rhythm; Corti | 2015 |
GABAB(1) receptor subunit isoforms differentially regulate stress resilience.
Topics: Anhedonia; Animals; Behavior, Animal; Cell Proliferation; Corticosterone; Depression; Disease Models | 2014 |
Elevated brain glucose and glycogen concentrations in an animal model of depression.
Topics: Animals; Brain; Corticosterone; Depressive Disorder; Disease Models, Animal; Female; Glucose; Glucos | 2014 |
Corticosterone mitigates the stress response in an animal model of PTSD.
Topics: Acoustic Stimulation; Animals; Anti-Inflammatory Agents; Corticosterone; Disease Models, Animal; Dos | 2015 |
Long-term corticosterone exposure decreases insulin sensitivity and induces depressive-like behaviour in the C57BL/6NCrl mouse.
Topics: Animals; Behavior, Animal; Blood Glucose; Corticosterone; Depression; Disease Models, Animal; Hypoth | 2014 |
A comparison of the short- and long-term effects of corticosterone exposure on extinction in adolescence versus adulthood.
Topics: Age Factors; Aging; Animals; Anti-Inflammatory Agents; Conditioning, Classical; Corticosterone; Dise | 2014 |
Behavioral effects of nicotinic antagonist mecamylamine in a rat model of depression: prefrontal cortex level of BDNF protein and monoaminergic neurotransmitters.
Topics: Animals; Behavior, Animal; Body Weight; Brain-Derived Neurotrophic Factor; Corticosterone; Depressiv | 2015 |
Osteopontin is associated with inflammation and mortality in a mouse model of polymicrobial sepsis.
Topics: Animals; Corticosterone; Cytokines; Disease Models, Animal; Inflammation; Interleukin-6; Male; Mice; | 2015 |
α-Klotho is an acute phase protein and altered by restraint stress in mice.
Topics: Acute-Phase Proteins; Animals; Biomarkers; Corticosterone; Disease Models, Animal; Glucuronidase; Kl | 2014 |
Antidepressant-like effects of a novel 5-HT3 receptor antagonist 6z in acute and chronic murine models of depression.
Topics: Acute Disease; Animals; Antidepressive Agents; Antioxidants; Behavior, Animal; Benzothiazoles; Bioma | 2014 |
Early-life stress selectively affects gastrointestinal but not behavioral responses in a genetic model of brain-gut axis dysfunction.
Topics: Animals; Anxiety; Brain; Colon; Corticosterone; Depression; Disease Models, Animal; Female; Gastroin | 2015 |
Brain-derived neurotrophic factor heterozygous mutant rats show selective cognitive changes and vulnerability to chronic corticosterone treatment.
Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Conditioning, Psychological; Corticosterone; Dise | 2015 |
Impact of social isolation and enriched environment during adolescence on voluntary ethanol intake and anxiety in C57BL/6J mice.
Topics: Age Factors; Alcohol Drinking; Analysis of Variance; Animals; Anxiety; Body Weight; Corticosterone; | 2015 |
Environmental enrichment and cafeteria diet attenuate the response to chronic variable stress in rats.
Topics: Adrenocorticotropic Hormone; Animals; Blood Glucose; Body Composition; Body Weight; Corticosterone; | 2015 |
Insulin-like growth factor 2 mitigates depressive behavior in a rat model of chronic stress.
Topics: Animals; Body Weight; Chronic Disease; Corticosterone; Depression; Disease Models, Animal; Food Pref | 2015 |
Honokiol abrogates lipopolysaccharide-induced depressive like behavior by impeding neuroinflammation and oxido-nitrosative stress in mice.
Topics: Animals; Antidepressive Agents; Biphenyl Compounds; Brain-Derived Neurotrophic Factor; Corticosteron | 2014 |
Increased antidepressant sensitivity after prefrontal cortex glucocorticoid receptor gene deletion in mice.
Topics: Animals; Antidepressive Agents; Corticosterone; Depressive Disorder; Disease Models, Animal; Gene Kn | 2015 |
Stress hormone corticosterone enhances susceptibility to cortical spreading depression in familial hemiplegic migraine type 1 mutant mice.
Topics: Animals; Cortical Spreading Depression; Corticosterone; Disease Models, Animal; Enzyme-Linked Immuno | 2015 |
Social overcrowding as a chronic stress model that increases adiposity in mice.
Topics: Adiponectin; Adiposity; Animals; Anxiety; Behavior, Animal; Body Weight; Corticosterone; Crowding; D | 2015 |
Nasal IgA secretion in a murine model of acute stress. The possible role of catecholamines.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Catecholamines; Corticosterone; | 2015 |
Social stress increases expression of hemoglobin genes in mouse prefrontal cortex.
Topics: Acute Disease; Animals; Body Weight; Chromatography, High Pressure Liquid; Chronic Disease; Corticos | 2014 |
Lack of GABAB receptors modifies behavioural and biochemical alterations induced by precipitated nicotine withdrawal.
Topics: Animals; Anxiety; Brain; Brain-Derived Neurotrophic Factor; Corticosterone; Disease Models, Animal; | 2015 |
Effects of different timing of stress on corticosterone, BDNF and memory in male rats.
Topics: Adaptation, Psychological; Animals; Avoidance Learning; Body Weight; Brain-Derived Neurotrophic Fact | 2015 |
Immunoendocrine dysbalance during uncontrolled T. cruzi infection is associated with the acquisition of a Th-1-like phenotype by Foxp3(+) T cells.
Topics: Adrenalectomy; Animals; Chagas Cardiomyopathy; Chagas Disease; Corticosterone; Dexamethasone; Diseas | 2015 |
Enterocolitis causes profound lymphoid depletion in endothelin receptor B- and endothelin 3-null mouse models of Hirschsprung-associated enterocolitis.
Topics: Animals; Colon; Corticosterone; Disease Models, Animal; Endothelin-3; Enterocolitis; Hirschsprung Di | 2015 |
Chronic desipramine prevents acute stress-induced reorganization of medial prefrontal cortex architecture by blocking glutamate vesicle accumulation and excitatory synapse increase.
Topics: Animals; Antidepressive Agents, Tricyclic; Corticosterone; Desipramine; Disease Models, Animal; Elec | 2014 |
Chronic stress shifts the GABA reversal potential in the hippocampus and increases seizure susceptibility.
Topics: Acute Disease; Animals; Bumetanide; Chronic Disease; Corticosterone; Disease Models, Animal; gamma-A | 2015 |
Grape powder prevents cognitive, behavioral, and biochemical impairments in a rat model of posttraumatic stress disorder.
Topics: Animals; Anxiety; Brain-Derived Neurotrophic Factor; Cognition; Corticosterone; Disease Models, Anim | 2015 |
Systemic administration of oleoylethanolamide protects from neuroinflammation and anhedonia induced by LPS in rats.
Topics: Amides; Anhedonia; Animals; Anti-Inflammatory Agents; Behavior, Animal; Body Temperature Regulation; | 2014 |
Antidepressant effects of abscisic acid mediated by the downregulation of corticotrophin-releasing hormone gene expression in rats.
Topics: Abscisic Acid; Animals; Antidepressive Agents; Cerebral Cortex; Corticosterone; Corticotropin-Releas | 2014 |
Role of the dorsomedial hypothalamus in glucocorticoid-mediated feedback inhibition of the hypothalamic-pituitary-adrenal axis.
Topics: Adrenalectomy; Animals; Circadian Rhythm; Corticosterone; Disease Models, Animal; Dorsomedial Hypoth | 2015 |
Chronic corticosterone exposure reduces hippocampal glycogen level and induces depression-like behavior in mice.
Topics: Animals; Astrocytes; Behavior, Animal; Brain; Corticosterone; Depression; Disease Models, Animal; Gl | 2015 |
Treadmill Running Reverses Cognitive Declines due to Alzheimer Disease.
Topics: Alzheimer Disease; Amyloid; Animals; Brain-Derived Neurotrophic Factor; Cognition Disorders; Cortico | 2015 |
Towards a better preclinical model of PTSD: characterizing animals with weak extinction, maladaptive stress responses and low plasma corticosterone.
Topics: Animals; Behavior, Animal; Conditioning, Classical; Corticosterone; Disease Models, Animal; Extincti | 2015 |
Chronic all-trans retinoic acid administration induces CRF over-expression accompanied by AVP up-regulation and multiple CRF-controlling receptors disturbance in the hypothalamus of rats.
Topics: Animals; Arginine Vasopressin; Corticosterone; Corticotropin-Releasing Hormone; Depression; Disease | 2015 |
A rodent model of traumatic stress induces lasting sleep and quantitative electroencephalographic disturbances.
Topics: Analysis of Variance; Animals; Brain Waves; Corticosterone; Disease Models, Animal; Electroencephalo | 2015 |
Chronic unpredictable mild stress decreases BDNF and NGF levels and Na(+),K(+)-ATPase activity in the hippocampus and prefrontal cortex of mice: antidepressant effect of chrysin.
Topics: Animals; Antidepressive Agents; Antioxidants; Brain-Derived Neurotrophic Factor; Catalase; Chronic D | 2015 |
Somatostatin, neuronal vulnerability and behavioral emotionality.
Topics: Adenine; Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Corticosterone; Disease | 2015 |
NLRP3 Inflammasome Mediates Chronic Mild Stress-Induced Depression in Mice via Neuroinflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Carrier Proteins; Caspase 1 | 2015 |
Investigating the stress attenuating potential of furosemide in immobilization and electric foot-shock stress models in mice.
Topics: Animals; Behavior, Animal; Corticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; | 2015 |
GPR39 (zinc receptor) knockout mice exhibit depression-like behavior and CREB/BDNF down-regulation in the hippocampus.
Topics: Animals; Brain-Derived Neurotrophic Factor; Corticosterone; CREB-Binding Protein; Dark Adaptation; D | 2014 |
In a rat model of panic, corticotropin responses to dorsal periaqueductal gray stimulation depend on physical exertion.
Topics: Adrenocorticotropic Hormone; Animals; Behavior, Animal; Corticosterone; Disease Models, Animal; Elec | 2015 |
Endocrine and metabolic function in male Carioca High-conditioned Freezing rats.
Topics: Adipose Tissue, Brown; Animals; Anxiety Disorders; Body Weight; CD3 Complex; CD4 Antigens; Cholester | 2015 |
Lymphocytes from chronically stressed mice confer antidepressant-like effects to naive mice.
Topics: Adoptive Transfer; Animals; Antidepressive Agents; Cell Proliferation; Chronic Disease; Corticostero | 2015 |
Melancholic-Like behaviors and circadian neurobiological abnormalities in melatonin MT1 receptor knockout mice.
Topics: Animals; Antidepressive Agents, Tricyclic; Chronobiology Disorders; Circadian Rhythm; Corticosterone | 2015 |
Ciproxifan differentially modifies cognitive impairment evoked by chronic stress and chronic corticosterone administration in rats.
Topics: Animals; Chronic Disease; Cognition Disorders; Corticosterone; Disease Models, Animal; Histamine H3 | 2015 |
Inhibition of endogenous glucocorticoid synthesis aggravates lung injury triggered by septic shock in rats.
Topics: Acute Lung Injury; Animals; Corticosterone; Disease Models, Animal; Down-Regulation; Enzyme Inhibito | 2015 |
[Impairments of rats' behavioral reactions, concentration of corticosterone and expression of cytokine's gene under experimental postviral fatigue].
Topics: Animals; Corticosterone; Disease Models, Animal; Fatigue Syndrome, Chronic; Gene Expression; Hypotha | 2014 |
The Vasopressin 1b Receptor Antagonist A-988315 Blocks Stress Effects on the Retrieval of Object-Recognition Memory.
Topics: Adrenocorticotropic Hormone; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressi | 2015 |
Constant light uncovers behavioral effects of a mutation in the schizophrenia risk gene Dtnbp1 in mice.
Topics: Animals; Anxiety; Circadian Rhythm; Corticosterone; Darkness; Disease Models, Animal; Dysbindin; Dys | 2015 |
Imipramine protects against the deleterious effects of chronic corticosterone on depression-like behavior, hippocampal reelin expression, and neuronal maturation.
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents, Tricyclic; Cell Adhesion Molecules, Neuron | 2015 |
Altered behavior of adult obese rats by monosodium l-glutamate neonatal treatment is related to hypercorticosteronemia and activation of hypothalamic ERK1 and ERK2.
Topics: Animals; Animals, Newborn; Behavior, Animal; Corticosterone; Disease Models, Animal; Enzyme Activati | 2017 |
Microemboli alter the acute stress response and cause prolonged expression of MCP-1 in the hippocampus.
Topics: Animals; Chemokine CCL2; Corticosterone; Disease Models, Animal; Gene Expression; Hippocampus; Hypot | 2015 |
CRTH2, a prostaglandin D2 receptor, mediates depression-related behavior in mice.
Topics: Animals; Brain; Carbazoles; Central Nervous System Agents; Chronic Disease; Corticosterone; Cyclooxy | 2015 |
Microglial activation enhances associative taste memory through purinergic modulation of glutamatergic neurotransmission.
Topics: Animals; Association Learning; Corticosterone; Cytokines; Disease Models, Animal; Encephalitis; Glut | 2015 |
Resveratrol Reduces Myometrial Infiltration, Uterine Hyperactivity, and Stress Levels and Alleviates Generalized Hyperalgesia in Mice With Induced Adenomyosis.
Topics: Adenomyosis; Animals; Animals, Newborn; Behavior, Animal; Cluster Analysis; Corticosterone; Disease | 2015 |
Hypothalamic-pituitary-adrenal axis and behavioral dysfunction following early binge-like prenatal alcohol exposure in mice.
Topics: Adrenocorticotropic Hormone; Animals; Anxiety; Behavior, Animal; Binge Drinking; Central Nervous Sys | 2015 |
Excess prenatal corticosterone exposure results in albuminuria, sex-specific hypotension, and altered heart rate responses to restraint stress in aged adult mice.
Topics: Age Factors; Albuminuria; Animals; Blood Pressure; Corticosterone; Disease Models, Animal; Dose-Resp | 2015 |
Knockdown of corticotropin-releasing factor in the central amygdala reverses persistent viscerosomatic hyperalgesia.
Topics: Analysis of Variance; Animals; Central Amygdaloid Nucleus; Corticosterone; Corticotropin-Releasing H | 2015 |
Corticosterone primes the neuroinflammatory response to DFP in mice: potential animal model of Gulf War Illness.
Topics: Animals; Anti-Inflammatory Agents; Chemical Warfare Agents; Cholinesterase Inhibitors; Corticosteron | 2015 |
Beyond the HPA-axis: The role of the gonadal steroid hormone receptors in modulating stress-related responses in an animal model of PTSD.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Brain; Chi-Square Distribution; Corticosterone; | 2015 |
Perinatal exposure to low-dose of bisphenol A causes anxiety-like alteration in adrenal axis regulation and behaviors of rat offspring: a potential role for metabotropic glutamate 2/3 receptors.
Topics: Adrenocorticotropic Hormone; Animals; Animals, Newborn; Anti-Inflammatory Agents; Anxiety; Benzhydry | 2015 |
Granulocyte-colony stimulating factor activates JAK2/PI3K/PDE3B pathway to inhibit corticosterone synthesis in a neonatal hypoxic-ischemic brain injury rat model.
Topics: Animals; Animals, Newborn; Body Weight; Brain Infarction; Cell Line; Cell Survival; Cholera Toxin; C | 2015 |
Hyper-responsivity to stress in rats is associated with a large increase in amygdala volume. A 7T MRI study.
Topics: Amygdala; Analysis of Variance; Animals; Corticosterone; Disease Models, Animal; Electroencephalogra | 2015 |
Blunted hypothalamo-pituitary adrenal axis response to predator odor predicts high stress reactivity.
Topics: Adrenocorticotropic Hormone; Analysis of Variance; Animals; Anxiety; Avoidance Learning; Brain; Cond | 2015 |
Stress inoculation modeled in mice.
Topics: Adaptation, Psychological; Animals; Behavior, Animal; Corticosterone; Disease Models, Animal; Male; | 2015 |
Increasing Adult Hippocampal Neurogenesis is Sufficient to Reduce Anxiety and Depression-Like Behaviors.
Topics: Animals; Anxiety; bcl-2-Associated X Protein; Bromodeoxyuridine; Corticosterone; Depression; Disease | 2015 |
Inhibiting corticosterone synthesis during fear memory formation exacerbates cued fear extinction memory deficits within the single prolonged stress model.
Topics: Animals; Conditioning, Psychological; Corticosterone; Cues; Disease Models, Animal; Enzyme Inhibitor | 2015 |
ApoE2 Exaggerates PTSD-Related Behavioral, Cognitive, and Neuroendocrine Alterations.
Topics: Activities of Daily Living; Animals; Apolipoprotein E2; Chronobiology Disorders; Cognition; Corticos | 2015 |
TLR4/NF-κB signaling contributes to chronic unpredictable mild stress-induced atherosclerosis in ApoE-/- mice.
Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Corticosterone; Cytokines; Disease Models, Anima | 2015 |
Antidepressant-like effects of oleoylethanolamide in a mouse model of chronic unpredictable mild stress.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Antioxidants; Atrophy; Brain-Derived Ne | 2015 |
Acute sleep fragmentation induces tissue-specific changes in cytokine gene expression and increases serum corticosterone concentration.
Topics: Adipose Tissue; Animals; Biomarkers; Brain; Corticosterone; Cytokines; Disease Models, Animal; Infla | 2015 |
Long-term effects of early adolescent stress: dysregulation of hypothalamic-pituitary-adrenal axis and central corticotropin releasing factor receptor 1 expression in adult male rats.
Topics: Animals; Anxiety; Corticosterone; Depression; Disease Models, Animal; Electroshock; Exercise Therapy | 2015 |
Changes in blood CD4+T and CD8+T lymphocytes in stressed rats pretreated chronically with desipramine are more pronounced after chronic open field stress challenge.
Topics: Animals; Antidepressive Agents, Tricyclic; Apoptosis; Body Weight; CD4-Positive T-Lymphocytes; CD8-P | 2015 |
Antidepressant-like effect of geniposide on chronic unpredictable mild stress-induced depressive rats by regulating the hypothalamus-pituitary-adrenal axis.
Topics: Animals; Antidepressive Agents; Chronic Disease; Corticosterone; Corticotropin-Releasing Hormone; De | 2015 |
Mice age - Does the age of the mother predict offspring behaviour?
Topics: Adaptation, Ocular; Age Factors; Aging; Animals; Anxiety; Corticosterone; Depression; Disease Models | 2015 |
Interaction of metabolic stress with chronic mild stress in altering brain cytokines and sucrose preference.
Topics: Animals; Blood Glucose; Body Weight; Chronic Disease; Corticosterone; Dietary Sucrose; Disease Model | 2015 |
Acute stress blocks the caffeine-induced enhancement of contextual memory retrieval in mice.
Topics: Acute Disease; Animals; Behavior, Animal; Caffeine; Cognition; Corticosterone; Cues; Discrimination, | 2015 |
[The hypothalamic-pituitary-adrenal axis activity in prenatal stressed female rats in the model of posttraumatic stress disorder].
Topics: Animals; Corticosterone; Corticotropin-Releasing Hormone; Disease Models, Animal; Female; Glucocorti | 2014 |
Investigations in foot shock stress of variable intensity in mice: Adaptation and role of angiotensin II.
Topics: Adaptation, Psychological; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Behavio | 2015 |
Dietary n-3 PUFAs Deficiency Increases Vulnerability to Inflammation-Induced Spatial Memory Impairment.
Topics: Animals; Animals, Newborn; Corticosterone; Cytokines; Dendritic Spines; Disease Models, Animal; Fatt | 2015 |
LC-MS/MS based studies on the anti-depressant effect of hypericin in the chronic unpredictable mild stress rat model.
Topics: Amino Acids; Animals; Anthracenes; Antidepressive Agents; Behavior, Animal; Chromatography, Liquid; | 2015 |
Novel sequential stress model for functional dyspepsia: Efficacy of the herbal preparation STW5.
Topics: Animals; Corticosterone; Corticotropin-Releasing Hormone; Disease Models, Animal; Dyspepsia; Female; | 2015 |
Acute restraint stress and corticosterone transiently disrupts novelty preference in an object recognition task.
Topics: Acute Disease; Animals; Corticosterone; Disease Models, Animal; Hormones; Male; Motor Activity; Neur | 2015 |
Short-term withdrawal from developmental exposure to cocaine activates the glucocorticoid receptor and alters spine dynamics.
Topics: Animals; Cocaine; Corticosterone; Dendritic Spines; Disease Models, Animal; Dopamine Uptake Inhibito | 2015 |
Affective dysfunction in a mouse model of Rett syndrome: Therapeutic effects of environmental stimulation and physical activity.
Topics: Animals; Behavior, Animal; Corticosterone; Disease Models, Animal; Female; Gene Expression Regulatio | 2016 |
m-Trifluoromethyl-diphenyl diselenide, a multi-target selenium compound, prevented mechanical allodynia and depressive-like behavior in a mouse comorbid pain and depression model.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Brain; Corticosterone; Cytokines; Depre | 2015 |
The Female Encounter Test: A Novel Method for Evaluating Reward-Seeking Behavior or Motivation in Mice.
Topics: Amino Acids; Animals; Antidepressive Agents, Second-Generation; Castration; Choice Behavior; Cortico | 2015 |
Prenatal stress, regardless of concurrent escitalopram treatment, alters behavior and amygdala gene expression of adolescent female rats.
Topics: Amygdala; Animals; Anxiety; Citalopram; Corticosterone; Disease Models, Animal; Estradiol; Female; g | 2015 |
Effects of intra-abdominal pressure on adrenal gland function and morphology in rats.
Topics: Adrenal Glands; Animals; Apoptosis; Corticosterone; Disease Models, Animal; Epinephrine; Intra-Abdom | 2015 |
Chronic social subordination stress modulates glutamic acid decarboxylase (GAD) 67 mRNA expression in central stress circuits.
Topics: Analysis of Variance; Animals; Body Composition; Body Weight; Brain; Brain-Derived Neurotrophic Fact | 2015 |
Stress-Induced Glucocorticoid Release Upregulates Uncoupling Protein-2 Expression and Enhances Resistance to Endotoxin-Induced Lethality.
Topics: Adrenocorticotropic Hormone; Animals; Cell Line, Transformed; Corticosterone; Cytokines; Disease Mod | 2015 |
Short-term modern life-like stress exacerbates Aβ-pathology and synapse loss in 3xTg-AD mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cells, Cultured; Corticosterone; Corticotropin-Re | 2015 |
Effect of castration on the susceptibility of male rats to the sleep deprivation-induced impairment of behavioral and synaptic plasticity.
Topics: Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cognition Disorders; Corticosterone; D | 2015 |
Intranasal delivery of progesterone after transient ischemic stroke decreases mortality and provides neuroprotection.
Topics: Administration, Intranasal; Animals; Blood-Brain Barrier; Brain; Brain Ischemia; Capillary Permeabil | 2015 |
Pineal Melatonin in a Sub-chronic Tryptophan Depletion Female Rat Model of Treatment-resistant Depression.
Topics: Aldosterone; Animals; Corticosterone; Depressive Disorder, Treatment-Resistant; Disease Models, Anim | 2015 |
Evidence against a critical role of CB1 receptors in adaptation of the hypothalamic-pituitary-adrenal axis and other consequences of daily repeated stress.
Topics: Adaptation, Psychological; Adrenocorticotropic Hormone; Animals; Body Weight; Cannabinoid Receptor A | 2015 |
Mice heterozygous for cathepsin D deficiency exhibit mania-related behavior and stress-induced depression.
Topics: Adaptation, Ocular; Animals; Antidepressive Agents; Bipolar Disorder; Cathepsin D; Corticosterone; D | 2015 |
Therapeutic antidepressant potential of a conjugated siRNA silencing the serotonin transporter after intranasal administration.
Topics: Administration, Intranasal; Animals; Antidepressive Agents; Arabidopsis Proteins; Brain; Corticoster | 2016 |
Neuropeptide Y administration reverses tricyclic antidepressant treatment-resistant depression induced by ACTH in mice.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents, Tricyclic; Corticosterone; Depressive D | 2015 |
Angelica gigas ameliorate depression-like symptoms in rats following chronic corticosterone injection.
Topics: Angelica; Animals; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Male; Plant | 2015 |
Phosphodiesterase-4D Knock-down in the Prefrontal Cortex Alleviates Chronic Unpredictable Stress-Induced Depressive-Like Behaviors and Memory Deficits in Mice.
Topics: Animals; Body Weight; Corticosterone; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cycli | 2015 |
Dexamethasone Treatment Leads to Enhanced Fear Extinction and Dynamic Fkbp5 Regulation in Amygdala.
Topics: Amygdala; Animals; Auditory Perception; Corticosterone; Dexamethasone; Disease Models, Animal; Dose- | 2016 |
Impaired adrenal medullary function in a mouse model of depression induced by unpredictable chronic stress.
Topics: Adrenal Medulla; Animals; Body Weight; Catecholamine Plasma Membrane Transport Proteins; Catecholami | 2015 |
Prenatal ethanol exposure-induced adrenal developmental abnormality of male offspring rats and its possible intrauterine programming mechanisms.
Topics: 3-Hydroxysteroid Dehydrogenases; Abnormalities, Drug-Induced; Adrenal Glands; Age Factors; Animals; | 2015 |
Disruption of peri-adolescent endocannabinoid signaling modulates adult neuroendocrine and behavioral responses to stress in male rats.
Topics: Adaptation, Psychological; Adrenocorticotropic Hormone; Animals; Brain; Cannabinoid Receptor Antagon | 2015 |
The effect of obestatin on anxiety-like behaviour in mice.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Corticosterone; Disease Models, Animal; | 2015 |
Adolescent-onset of cocaine use is associated with heightened stress-induced reinstatement of cocaine seeking.
Topics: Age of Onset; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Psycholog | 2016 |
Beneficial effects of a ketamine/atropine combination in soman-poisoned rats under a neutral thermal environment.
Topics: Animals; Anticonvulsants; Atropine; Body Temperature; Brain; Brain Injuries; Chemical Warfare Agents | 2015 |
The hypothalamic transcriptional response to stress is severely impaired in offspring exposed to adverse nutrition during gestation.
Topics: Animals; Circadian Rhythm; Corticosterone; Diet, High-Fat; Diet, Protein-Restricted; Disease Models, | 2017 |
MeCP2 controls hippocampal brain-derived neurotrophic factor expression via homeostatic interactions with microRNA‑132 in rats with depression.
Topics: Animals; Brain-Derived Neurotrophic Factor; Case-Control Studies; Corticosterone; Depression; Depres | 2015 |
Calcitonin gene-related peptide pre-administration acts as a novel antidepressant in stressed mice.
Topics: Animals; Antidepressive Agents; Calcitonin Gene-Related Peptide; Cell Line; Corticosterone; Depressi | 2015 |
Antileukemic Efficacy of Continuous vs Discontinuous Dexamethasone in Murine Models of Acute Lymphoblastic Leukemia.
Topics: Adolescent; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; C | 2015 |
A Method for Psychosocial Stress-Induced Reinstatement of Cocaine Seeking in Rats.
Topics: Adaptation, Psychological; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corti | 2016 |
Evidence for protective effect of lipoic acid and desvenlafaxine on oxidative stress in a model depression in mice.
Topics: Animals; Antidepressive Agents; Antioxidants; Corpus Striatum; Corticosterone; Depressive Disorder; | 2016 |
TrkB in the hippocampus and nucleus accumbens differentially modulates depression-like behavior in mice.
Topics: Animals; Anxiety; Astrocytes; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; | 2016 |
GABAergic control of the activity of the central nucleus of the amygdala in low- and high-anxiety rats.
Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Basolateral Nuclear Complex; Central Amygdaloid Nuc | 2015 |
Behavioural and neurobiological consequences of macrophage migration inhibitory factor gene deletion in mice.
Topics: Animals; Biogenic Monoamines; Corticosterone; Cytokines; Depression; Disease Models, Animal; Explora | 2015 |
Short-Term Sleep Disturbance-Induced Stress Does not Affect Basal Pain Perception, but Does Delay Postsurgical Pain Recovery.
Topics: Animals; Chronic Disease; Corticosterone; Disease Models, Animal; Disease Progression; Female; Gangl | 2015 |
Prenatal alcohol exposure and prenatal stress differentially alter glucocorticoid signaling in the placenta and fetal brain.
Topics: Animals; Blotting, Western; Brain; Central Nervous System Depressants; Corticosterone; Disease Model | 2017 |
Electrical stimulation of the amygdala modifies the negative feedback effect of glucocorticoids on the adrenocortical responses to stress.
Topics: Acoustic Stimulation; Animals; Central Amygdaloid Nucleus; Corticosterone; Dexamethasone; Disease Mo | 2015 |
Depressive-like phenotype induced by AAV-mediated overexpression of human α-synuclein in midbrain dopaminergic neurons.
Topics: Adrenocorticotropic Hormone; alpha-Synuclein; Animals; Corticosterone; Dependovirus; Depression; Dis | 2015 |
Maternal postpartum corticosterone and fluoxetine differentially affect adult male and female offspring on anxiety-like behavior, stress reactivity, and hippocampal neurogenesis.
Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Anxiety; Corticosterone; Dexamethasone; Disease Mode | 2016 |
Antidepressant-like activity and cardioprotective effects of fatty acid amide hydrolase inhibitor URB694 in socially stressed Wistar Kyoto rats.
Topics: Amidohydrolases; Anhedonia; Animals; Antidepressive Agents; Arrhythmias, Cardiac; Biphenyl Compounds | 2015 |
Local corticosterone production and angiotensin-I converting enzyme shedding in a mouse model of intestinal inflammation.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Colitis; Colon; Cortic | 2015 |
Colony-Specific Differences in Endocrine and Immune Responses to an Inflammatory Challenge in Female Sprague Dawley Rats.
Topics: Adjuvants, Immunologic; Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Chemokine CCL2; Che | 2015 |
Chronic stress and peripheral pain: Evidence for distinct, region-specific changes in visceral and somatosensory pain regulatory pathways.
Topics: Afferent Pathways; Animals; Arachidonic Acids; Corticosterone; Cyclooxygenase 2; Disease Models, Ani | 2015 |
Neonatal tactile stimulation decreases depression-like and anxiety-like behaviors and potentiates sertraline action in young rats.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Anxiety; Corticosterone; Depression; D | 2015 |
Geraniol produces antidepressant-like effects in a chronic unpredictable mild stress mice model.
Topics: Acyclic Monoterpenes; Animals; Antidepressive Agents; Carrier Proteins; Caspase 1; Chronic Disease; | 2015 |
Dissociation in control of physiological and behavioral responses to emotional stress by cholinergic neurotransmission in the bed nucleus of the stria terminalis in rats.
Topics: Analysis of Variance; Animals; Blood Pressure; Cholinergic Agents; Corticosterone; Disease Models, A | 2016 |
Baicalin decreases SGK1 expression in the hippocampus and reverses depressive-like behaviors induced by corticosterone.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Animals; Antidepressive Agents; Brain-Derived Neurotrop | 2015 |
Depression-like episodes in mice harboring mtDNA deletions in paraventricular thalamus.
Topics: Animals; Comorbidity; Corticosterone; Depressive Disorder; Disease Models, Animal; DNA Polymerase ga | 2016 |
A potential mechanism underlying atypical antipsychotics-induced lipid disturbances.
Topics: Animals; Antipsychotic Agents; Blotting, Western; Cholesterol; Clozapine; Corticosterone; Disease Mo | 2015 |
Mortality of Septic Mice Strongly Correlates With Adrenal Gland Inflammation.
Topics: Adrenal Glands; Adrenal Insufficiency; Adrenocorticotropic Hormone; Animals; Cecum; Corticosterone; | 2016 |
Effect of unilateral adrenalectomy on acute immobilization stress response in rats.
Topics: Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Animals; Catecholamines; Corticosterone; | 2015 |
Biological variations in adrenal gland response to immobilization and glucoprivation stressors in rats.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Catecholamines; Corticosterone; Disease Models | 2015 |
Resistance training minimizes catabolic effects induced by sleep deprivation in rats.
Topics: Animals; Autophagy; Corticosterone; Disease Models, Animal; Insulin-Like Growth Factor I; Male; Musc | 2015 |
Infralimbic cortex controls the activity of the hypothalamus-pituitary-adrenal axis and the formation of aversive memory: Effects of environmental enrichment.
Topics: Animals; Avoidance Learning; Cerebral Cortex; Corticosterone; Disease Models, Animal; Emotions; Envi | 2016 |
Protective Effect of Moderate Exercise for BALB/c Mice with Salmonella Typhimurium Infection.
Topics: Animals; Bacterial Load; Corticosterone; Disease Models, Animal; Disease Resistance; Immunoglobulin | 2016 |
Enzymatic Depletion of the Polysialic Acid Moiety Associated with the Neural Cell Adhesion Molecule Inhibits Antidepressant Efficacy.
Topics: Animals; Antidepressive Agents, Second-Generation; Corticosterone; Depression; Disease Models, Anima | 2016 |
Systemic Staphylococcus aureus infection in restraint stressed mice modulates impaired immune response resulting in improved behavioral activities.
Topics: Animals; Behavior, Animal; Corticosterone; Cytokines; Disease Models, Animal; Enzyme-Linked Immunoso | 2015 |
Vicarious social defeat stress: Bridging the gap between physical and emotional stress.
Topics: Animals; Behavior, Animal; Corticosterone; Disease Models, Animal; Fear; Male; Mice; Social Behavior | 2016 |
Effectiveness of different corticosterone administration methods to elevate corticosterone serum levels, induce depressive-like behavior, and affect neurogenesis levels in female rats.
Topics: Animals; Behavior, Animal; Body Weight; Corticosterone; Dentate Gyrus; Depression; Disease Models, A | 2016 |
The Role of Nitric Oxide in the Antidepressant Actions of 5-Aminoimidazole-4-Carboxamide-1-β-D-Ribofuranoside in Insulin-Resistant Mice.
Topics: Adenylate Kinase; Aminoimidazole Carboxamide; Animals; Antidepressive Agents; Combined Modality Ther | 2016 |
Chronic corticosterone-mediated dysregulation of microRNA network in prefrontal cortex of rats: relevance to depression pathophysiology.
Topics: Animals; Behavior, Animal; Corticosterone; Depressive Disorder; Disease Models, Animal; Gene Regulat | 2015 |
Chronic Stress Facilitates the Development of Deep Venous Thrombosis.
Topics: Animals; Antioxidants; Blood Platelets; Corticosterone; Cyclic N-Oxides; Disease Models, Animal; Enz | 2015 |
Biochemical and cognitive impairments observed in animal models of schizophrenia induced by prenatal stress paradigm or methylazoxymethanol acetate administration.
Topics: Analysis of Variance; Animals; Brain-Derived Neurotrophic Factor; Cognition Disorders; Corticosteron | 2015 |
SLC6A15, a novel stress vulnerability candidate, modulates anxiety and depressive-like behavior: involvement of the glutamatergic system.
Topics: Alleles; Amino Acid Transport Systems, Neutral; Animals; Anxiety; Behavior, Animal; Corticosterone; | 2016 |
Evaluation of adaptogenic-like property of methyl jasmonate in mice exposed to unpredictable chronic mild stress.
Topics: Acetates; Adaptation, Ocular; Adrenal Glands; Analysis of Variance; Animals; Anti-Anxiety Agents; Bl | 2016 |
Behavioral and physiological response to onset and termination of social instability in female mice.
Topics: Animals; Anxiety; Behavior, Animal; Corticosterone; Disease Models, Animal; Female; Hair; Mice; Soci | 2016 |
Antidepressant-like effect of the water extract of the fixed combination of Gardenia jasminoides, Citrus aurantium and Magnolia officinalis in a rat model of chronic unpredictable mild stress.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Citr | 2015 |
Dysregulation of Neuregulin-1/ErbB signaling in the prefrontal cortex and hippocampus of rats exposed to chronic unpredictable mild stress.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Corticosterone; Disease Models, Animal; Food P | 2016 |
Time-dependent miR-16 serum fluctuations together with reciprocal changes in the expression level of miR-16 in mesocortical circuit contribute to stress resilient phenotype in chronic mild stress - An animal model of depression.
Topics: Anhedonia; Animals; Biomarkers; Chronic Disease; Corticosterone; Depressive Disorder; Dietary Sucros | 2016 |
From Memory Impairment to Posttraumatic Stress Disorder-Like Phenotypes: The Critical Role of an Unpredictable Second Traumatic Experience.
Topics: AIDS-Related Complex; Animals; Avoidance Learning; Brain-Derived Neurotrophic Factor; Corticosterone | 2015 |
Myricetin Attenuates Depressant-Like Behavior in Mice Subjected to Repeated Restraint Stress.
Topics: Animals; Antidepressive Agents; Antioxidants; Behavior, Animal; Brain-Derived Neurotrophic Factor; C | 2015 |
Short photoperiod condition increases susceptibility to stress in adolescent male rats.
Topics: Aging; Anhedonia; Animals; Circadian Rhythm; Corticosterone; Disease Models, Animal; Disease Suscept | 2016 |
High-Fat Diet Induced Anxiety and Anhedonia: Impact on Brain Homeostasis and Inflammation.
Topics: Anhedonia; Animals; Anxiety; Body Weight; Brain; Corticosterone; Diet, High-Fat; Disease Models, Ani | 2016 |
Long-term characterization of the Flinders Sensitive Line rodent model of human depression: Behavioral and PET evidence of a dysfunctional entorhinal cortex.
Topics: Aging; Animals; Brain Mapping; Corticosterone; Depressive Disorder; Disease Models, Animal; Entorhin | 2016 |
Creatine, Similar to Ketamine, Counteracts Depressive-Like Behavior Induced by Corticosterone via PI3K/Akt/mTOR Pathway.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corticosterone; | 2016 |
Investigating the role of nisoldipine in foot-shock-induced post-traumatic stress disorder in mice.
Topics: Animals; Anxiety; Behavior, Animal; Corticosterone; Disease Models, Animal; Electroshock; Mice; Moto | 2016 |
An association between neuropeptide Y levels and leukocyte subsets in stress-exacerbated asthmatic mice.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Corticosterone; Disease Models, Animal; Inflammation; | 2016 |
Inhibition of Acid Sphingomyelinase by Antidepressants Counteracts Stress-Induced Activation of P38-Kinase in Major Depression.
Topics: Adaptation, Ocular; Amitriptyline; Animals; Antidepressive Agents; Corticosterone; Disease Models, A | 2015 |
Decreased daytime illumination leads to anxiety-like behaviors and HPA axis dysregulation in the diurnal grass rat (Arvicanthis niloticus).
Topics: Animals; Anxiety Disorders; Circadian Rhythm; Corticosterone; Corticotropin-Releasing Hormone; Disea | 2016 |
Modulation of the antioxidant nuclear factor (erythroid 2-derived)-like 2 pathway by antidepressants in rats.
Topics: Animals; Antidepressive Agents; Antioxidants; Corticosterone; Depressive Disorder; Disease Models, A | 2016 |
In-depth behavioral characterization of the corticosterone mouse model and the critical involvement of housing conditions.
Topics: Animals; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Exploratory Behavior; | 2016 |
Lithium attenuated the depressant and anxiogenic effect of juvenile social stress through mitigating the negative impact of interlukin-1β and nitric oxide on hypothalamic-pituitary-adrenal axis function.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; Corticosterone; Depressive D | 2016 |
Antidepressant-like effects of Sanyuansan in the mouse forced swim test, tail suspension test, and chronic mild stress model.
Topics: Anhedonia; Animals; Antidepressive Agents; Chronic Disease; Corticosterone; Disease Models, Animal; | 2015 |
Effects of Escitalopram on a Rat Model of Persistent Stress-Altered Hedonic Activities: Towards a New Understanding of Stress and Depression.
Topics: Age Factors; Animals; Antidepressive Agents, Second-Generation; Citalopram; Corticosterone; Depressi | 2015 |
Sulforaphane produces antidepressant- and anxiolytic-like effects in adult mice.
Topics: Adrenocorticotropic Hormone; Animals; Anti-Anxiety Agents; Anti-Inflammatory Agents; Antidepressive | 2016 |
Treadmill exercise ameliorates ischemia-induced brain edema while suppressing Na⁺/H⁺ exchanger 1 expression.
Topics: Acid Sensing Ion Channel Blockers; Animals; Aquaporin 4; Brain Edema; Cells, Cultured; Corticosteron | 2016 |
Rhythmical Photic Stimulation at Alpha Frequencies Produces Antidepressant-Like Effects in a Mouse Model of Depression.
Topics: Animals; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Fluoxetine; Male; Mic | 2016 |
Chronical sleep interruption-induced cognitive decline assessed by a metabolomics method.
Topics: Animals; Body Weight; Catalase; Chromatography, Liquid; Cognition Disorders; Corticosterone; Disease | 2016 |
Anxiety- and Depression-Like States Lead to Pronounced Olfactory Deficits and Impaired Adult Neurogenesis in Mice.
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents, Second-Generation; Anxiety; Cell Prolifera | 2016 |
Testosterone has antidepressant-like efficacy and facilitates imipramine-induced neuroplasticity in male rats exposed to chronic unpredictable stress.
Topics: Animals; Antidepressive Agents; Chronic Disease; Corticosterone; Dentate Gyrus; Depression; Disease | 2016 |
Prenatal immune activation in mice blocks the effects of environmental enrichment on exploratory behavior and microglia density.
Topics: Age Factors; Amphetamine; Analysis of Variance; Animals; Brain; Central Nervous System Stimulants; C | 2016 |
Combined effects of social stress and liver fluke infection in a mouse model.
Topics: Adrenal Glands; Animals; Behavior, Animal; Brain; Cathepsin B; Cathepsin L; Corticosterone; Disease | 2016 |
Investigations on GSK-3β/NF-kB signaling in stress and stress adaptive behavior in electric foot shock subjected mice.
Topics: Adaptation, Psychological; Adjuvants, Immunologic; Animals; Brain; Corticosterone; Disease Models, A | 2016 |
Opposite Sex Contact and Isolation: A Novel Depression/Anxiety Model.
Topics: Animals; Anxiety; Behavior, Animal; Corticosterone; Cyclic AMP Response Element-Binding Protein; Dep | 2016 |
Parity modifies the effects of fluoxetine and corticosterone on behavior, stress reactivity, and hippocampal neurogenesis.
Topics: Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Corticosterone; Dentate Gyrus; | 2016 |
Behavioral and hormonal responses to stress in binge-like eating prone female rats.
Topics: Age Factors; Analysis of Variance; Animals; Binge-Eating Disorder; Compulsive Behavior; Corticostero | 2016 |
Neuropeptide Y Impairs Retrieval of Extinguished Fear and Modulates Excitability of Neurons in the Infralimbic Prefrontal Cortex.
Topics: Animals; Arginine; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Corticosterone; Disease Model | 2016 |
Severe, multimodal stress exposure induces PTSD-like characteristics in a mouse model of single prolonged stress.
Topics: Animals; Behavior, Animal; Conditioning, Classical; Corticosterone; Cues; Disease Models, Animal; Ex | 2016 |
JNK: A Putative Link Between Insulin Signaling and VGLUT1 in Alzheimer's Disease.
Topics: Aged; Alzheimer Disease; Animals; Brain; Corticosterone; Disease Models, Animal; Female; Humans; Ins | 2016 |
Effects of different periods of paradoxical sleep deprivation and sleep recovery on lipid and glucose metabolism and appetite hormones in rats.
Topics: Animals; Appetite Regulation; Biomarkers; Blood Glucose; Body Weight; Corticosterone; Disease Models | 2016 |
Neonatal proinflammatory challenge in male Wistar rats: Effects on behavior, synaptic plasticity, and adrenocortical stress response.
Topics: Age Factors; Animals; Animals, Newborn; Anxiety; Conditioning, Psychological; Corticosterone; Depres | 2016 |
DHEA administration modulates stress-induced analgesia in rats.
Topics: Analgesics; Analysis of Variance; Animals; Corticosterone; Dehydroepiandrosterone; Disease Models, A | 2016 |
Apelin-13 exerts antidepressant-like and recognition memory improving activities in stressed rats.
Topics: Animals; Antidepressive Agents; Chromones; Corticosterone; Depression; Disease Models, Animal; Enzym | 2016 |
Alcohol withdrawal induces long-lasting spatial working memory impairments: relationship with changes in corticosterone response in the prefrontal cortex.
Topics: Alcoholism; Animals; Behavior, Animal; Corticosterone; Disease Models, Animal; Hippocampus; Male; Me | 2017 |
Icariin reverses corticosterone-induced depression-like behavior, decrease in hippocampal brain-derived neurotrophic factor (BDNF) and metabolic network disturbances revealed by NMR-based metabonomics in rats.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corticosterone; | 2016 |
Cox-2 Plays a Vital Role in the Impaired Anxiety Like Behavior in Colchicine Induced Rat Model of Alzheimer Disease.
Topics: Alzheimer Disease; Animals; Anxiety; Behavior, Animal; Colchicine; Corticosterone; Cyclooxygenase 2; | 2016 |
Methamphetamine abstinence induces changes in μ-opioid receptor, oxytocin and CRF systems: Association with an anxiogenic phenotype.
Topics: Amphetamine-Related Disorders; Amygdala; Animals; Anxiety; Central Nervous System Stimulants; Corpus | 2016 |
Effects of In utero environment and maternal behavior on neuroendocrine and behavioral alterations in a mouse model of prenatal trauma.
Topics: Animals; Anxiety; Behavior, Animal; Conditioning, Classical; Corticosterone; Disease Models, Animal; | 2016 |
Corticosterone levels and behavioral changes induced by simultaneous exposure to chronic social stress and enriched environments in NMRI male mice.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Body Weight; Corticosterone; Disease M | 2016 |
5-(4-hydroxy-3-dimethoxybenzylidene)-rhodanine (RD-1)-improved mitochondrial function prevents anxiety- and depressive-like states induced by chronic corticosterone injections in mice.
Topics: Administration, Oral; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; Biolog | 2016 |
Substrain and light regime effects on integrated anxiety-related behavioral z-scores in male C57BL/6 mice-Hypomagnesaemia has only a small effect on avoidance behavior.
Topics: Adaptation, Ocular; Animals; Anxiety; Avoidance Learning; Body Weight; Brain; Corticosterone; Diseas | 2016 |
Urinary bladder hypersensitivity and dysfunction in female mice following early life and adult stress.
Topics: Animals; Animals, Newborn; Colon; Corticosterone; Cytokines; Disease Models, Animal; Female; Hippoca | 2016 |
Glucocorticoids Induce Nondipping Blood Pressure by Activating the Thiazide-Sensitive Cotransporter.
Topics: Animals; Blood Pressure; Blood Pressure Determination; Circadian Rhythm; Corticosterone; Disease Mod | 2016 |
Antidepressant-Like Effect of Ropren® in β-Amyloid-(25-35) Rat Model of Alzheimer's Disease with Altered Levels of Androgens.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Androgens; Animals; Antidepressive Agents; Corticosterone; | 2017 |
A high-fat diet combined with food deprivation increases food seeking and the expression of candidate biomarkers of addiction.
Topics: Animals; Behavior, Addictive; Behavior, Animal; Biomarkers; Corticosterone; Diet, High-Fat; Disease | 2017 |
Brainstem metabotropic glutamate receptors reduce food intake and activate dorsal pontine and medullar structures after peripheral bacterial lipopolysaccharide administration.
Topics: Animals; Body Weight; Brain Stem; Corticosterone; Disease Models, Animal; Eating; Escherichia coli; | 2016 |
ERK-dependent brain-derived neurotrophic factor regulation by hesperidin in mice exposed to chronic mild stress.
Topics: Aminoacetonitrile; Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Corticosterone | 2016 |
Ovarian hormones, but not fluoxetine, impart resilience within a chronic unpredictable stress model in middle-aged female rats.
Topics: Age Factors; Animals; Antidepressive Agents; Corticosterone; Disease Models, Animal; Estradiol; Fema | 2016 |
Activity of the Hypothalamic-Pituitary-Adrenal System in Prenatally Stressed Male Rats on the Experimental Model of Post-Traumatic Stress Disorder.
Topics: Animals; Corticosterone; Corticotropin-Releasing Hormone; Disease Models, Animal; Female; Hypothalam | 2016 |
Blood glucose regulation mechanism in depressive disorder animal model during hyperglycemic states.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Blood Glucose; Clonidine; Corticosterone; Depressive | 2016 |
Chronic intermittent ethanol exposure during adolescence: Effects on stress-induced social alterations and social drinking in adulthood.
Topics: Aging; Alcohol Drinking; Animals; Anxiety; Binge Drinking; Central Nervous System Depressants; Corti | 2017 |
Antidepressant-like Effects of LPM580153, A Novel Potent Triple Reuptake Inhibitor.
Topics: Anhedonia; Animals; Antidepressive Agents; Biological Transport; Blotting, Western; Brain-Derived Ne | 2016 |
Chronic unpredictable mild stress generates oxidative stress and systemic inflammation in rats.
Topics: Analysis of Variance; Animals; Catalase; Corticosterone; Cytokines; Disease Models, Animal; Food Dep | 2016 |
Altered monoamine system activities after prenatal and adult stress: A role for stress resilience?
Topics: Action Potentials; Animals; Corticosterone; Disease Models, Animal; Dopamine; Female; Male; Mesencep | 2016 |
Estrogen Receptor-α in the Medial Amygdala Prevents Stress-Induced Elevations in Blood Pressure in Females.
Topics: Amygdala; Animals; Blood Pressure Determination; Blotting, Western; Corticosterone; Disease Models, | 2016 |
Neuroinflammation: effect of surgical stress compared to anaesthesia and effect of physostigmine.
Topics: Acetylcholine; Anesthesia; Animals; Cholinesterase Inhibitors; Cholinesterases; Corticosterone; Cyto | 2016 |
3,5,6,7,8,3',4'-Heptamethoxyflavone, a Citrus Flavonoid, Ameliorates Corticosterone-Induced Depression-like Behavior and Restores Brain-Derived Neurotrophic Factor Expression, Neurogenesis, and Neuroplasticity in the Hippocampus.
Topics: Animals; Behavior, Animal; Body Weight; Brain-Derived Neurotrophic Factor; Citrus; Corticosterone; D | 2016 |
Maternal corticosterone exposure in the mouse programs sex-specific renal adaptations in the renin-angiotensin-aldosterone system in 6-month offspring.
Topics: Angiotensin II; Animals; Blotting, Western; Corticosterone; Disease Models, Animal; Female; Kidney; | 2016 |
Glucocorticoid receptor mediated the propofol self-administration by dopamine D1 receptor in nucleus accumbens.
Topics: Aldosterone; Animals; Corticosterone; Dexamethasone; Disease Models, Animal; Dose-Response Relations | 2016 |
Fourteen-day administration of corticosterone may induce detrusor overactivity symptoms.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Corticosterone; Depression; Disease | 2016 |
Anxiolytic effects of GLYX-13 in animal models of posttraumatic stress disorder-like behavior.
Topics: Adrenocorticotropic Hormone; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Corticosterone | 2016 |
A novel role for the mineralocorticoid receptor in glucocorticoid driven vascular calcification.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Apoptosis; Corticosterone; Disease Models, Ani | 2016 |
Sleep restriction reduces the survival time and aggravates the neurological dysfunction and memory impairments in an animal model of cerebral hypoperfusion.
Topics: Animals; Brain Ischemia; CA1 Region, Hippocampal; Cerebral Cortex; Corticosterone; Disease Models, A | 2016 |
Genetic predisposition for high stress reactivity amplifies effects of early-life adversity.
Topics: Adaptation, Psychological; Animals; Brain; Corticosterone; Depressive Disorder, Major; Disease Model | 2016 |
Conditioned stress prevents cue-primed cocaine reinstatement only in stress-responsive rats.
Topics: Amygdala; Animals; Cocaine; Cocaine-Related Disorders; Corticosterone; Corticotropin-Releasing Hormo | 2016 |
Pro-apoptotic Action of Corticosterone in Hippocampal Organotypic Cultures.
Topics: Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Caspase 3; Cell Survival; Cells, Cultured; Co | 2016 |
p-Chloro-diphenyl diselenide reverses memory impairment-related to stress caused by corticosterone and modulates hippocampal [(3)H]glutamate uptake in mice.
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents; Avoidance Learning; Corticosterone; Diseas | 2016 |
Hypothalamic Proteomic Analysis Reveals Dysregulation of Glutamate Balance and Energy Metabolism in a Mouse Model of Chronic Mild Stress-Induced Depression.
Topics: Animals; Corticosterone; Depression; Depressive Disorder; Disease Models, Animal; Energy Metabolism; | 2016 |
Altered brain morphology and functional connectivity reflect a vulnerable affective state after cumulative multigenerational stress in rats.
Topics: Animals; Brain; Cell Count; Contrast Media; Corticosterone; Disease Models, Animal; Emotions; Explor | 2016 |
BDNF Val66Met Genotype Interacts With a History of Simulated Stress Exposure to Regulate Sensorimotor Gating and Startle Reactivity.
Topics: Animals; Brain-Derived Neurotrophic Factor; Corticosterone; Disease Models, Animal; Female; Male; Me | 2017 |
Fluoxetine normalizes the effects of prenatal maternal stress on depression- and anxiety-like behaviors in mouse dams and male offspring.
Topics: Animals; Animals, Newborn; Anxiety Disorders; Corticosterone; Depressive Disorder; Disease Models, A | 2016 |
Simultaneous Changes in Sleep, qEEG, Physiology, Behaviour and Neurochemistry in Rats Exposed to Repeated Social Defeat Stress.
Topics: Animals; Behavior, Animal; Brain; Corticosterone; Depression; Disease Models, Animal; Dopamine; Elec | 2016 |
Diurnal Variation of the Peripheral Cholinergic Antiinflammatory Function in Mice.
Topics: Acetylcholine; Aconitine; Animals; Circadian Rhythm; Corticosterone; Cytokines; Disease Models, Anim | 2016 |
Fructose and stress induce opposite effects on lipid metabolism in the visceral adipose tissue of adult female rats through glucocorticoid action.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Acetyl-CoA Carboxylase; Animals; Corticosterone; Diet; | 2017 |
Depression-Like Adult Behaviors may be a Long-Term Result of Experimental Pneumococcal Meningitis in Wistar Rats Infants.
Topics: Animals; Behavior, Animal; Brain; Brain-Derived Neurotrophic Factor; Corticosterone; Depression; Dis | 2016 |
Corticosterone dysregulation exacerbates disease progression in the R6/2 transgenic mouse model of Huntington's disease.
Topics: Adrenalectomy; Age Factors; Animals; Anti-Inflammatory Agents; Body Weight; Corticosterone; Disease | 2016 |
Relationship between the Balance of Hypertrophic/Hyperplastic Adipose Tissue Expansion and the Metabolic Profile in a High Glucocorticoids Model.
Topics: Adipocytes; Adipogenesis; Adiposity; Animals; Cell Differentiation; Cell Proliferation; Cells, Cultu | 2016 |
Repeated treatment with oxytocin promotes hippocampal cell proliferation, dendritic maturation and affects socio-emotional behavior.
Topics: Animals; Anxiety; Cell Proliferation; Corticosterone; Dendrites; Dentate Gyrus; Depression; Disease | 2016 |
Involvement of hippocampal excitability in amyloid β-induced behavioral and psychological symptoms of dementia.
Topics: Aggression; Alzheimer Disease; Amyloid beta-Peptides; Animals; Anxiety; Behavior, Animal; Cognition; | 2016 |
Evaluation of the antidepressant-like effect of musk in an animal model of depression: how it works.
Topics: Administration, Inhalation; Animals; Antidepressive Agents; Behavior; Brain-Derived Neurotrophic Fac | 2017 |
Cognitive and affective alterations by prenatal and postnatal stress interaction.
Topics: Animals; Chronic Disease; Cognition; Corticosterone; Disease Models, Animal; Dominance-Subordination | 2016 |
miR-17-92 Cluster Regulates Adult Hippocampal Neurogenesis, Anxiety, and Depression.
Topics: Aging; Animals; Anxiety; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Hippo | 2016 |
The antidepressant effect of musk in an animal model of depression: a histopathological study.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Caspase 3; Corticosterone; Depres | 2016 |
Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat.
Topics: Adult; Aged; Animals; C-Reactive Protein; Case-Control Studies; Corticosterone; Cytokines; Depressio | 2016 |
Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat.
Topics: Adult; Aged; Animals; C-Reactive Protein; Case-Control Studies; Corticosterone; Cytokines; Depressio | 2016 |
Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat.
Topics: Adult; Aged; Animals; C-Reactive Protein; Case-Control Studies; Corticosterone; Cytokines; Depressio | 2016 |
Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat.
Topics: Adult; Aged; Animals; C-Reactive Protein; Case-Control Studies; Corticosterone; Cytokines; Depressio | 2016 |
Traumatic stress causes distinctive effects on fear circuit catecholamines and the fear extinction profile in a rodent model of posttraumatic stress disorder.
Topics: Animals; Blood Pressure; Brain; Conditioning, Classical; Corticosterone; Disease Models, Animal; Dop | 2016 |
Baicalin promotes hippocampal neurogenesis via SGK1- and FKBP5-mediated glucocorticoid receptor phosphorylation in a neuroendocrine mouse model of anxiety/depression.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Anxiety; Behavior, Anima | 2016 |
Neuroprotective, Neurotrophic and Anti-oxidative Role of Bacopa monnieri on CUS Induced Model of Depression in Rat.
Topics: Animals; Antidepressive Agents; Antioxidants; Bacopa; Behavior, Animal; Corticosterone; Depression; | 2016 |
Bilobalide alleviates depression-like behavior and cognitive deficit induced by chronic unpredictable mild stress in mice.
Topics: Animals; Behavior, Animal; Cognition Disorders; Corticosterone; Cyclopentanes; Depression; Discrimin | 2016 |
Hormonal and molecular effects of restraint stress on formalin-induced pain-like behavior in male and female mice.
Topics: Analysis of Variance; Animals; Corticosterone; Disease Models, Animal; Female; Fixatives; Formaldehy | 2016 |
Glucose intolerance after chronic stress is related with downregulated PPAR-γ in adipose tissue.
Topics: Animals; Biomarkers; Blood Glucose; Chronic Disease; Corticosterone; Disease Models, Animal; Down-Re | 2016 |
Effects of chronic noise on mRNA and protein expression of CRF family molecules and its relationship with p-tau in the rat prefrontal cortex.
Topics: Acoustic Stimulation; Animals; Corticosterone; Corticotropin-Releasing Hormone; Disease Models, Anim | 2016 |
Short- and long-term effects of stress during adolescence on emotionality and HPA function of animals exposed to alcohol prenatally.
Topics: Age Factors; Animals; Anxiety; Basolateral Nuclear Complex; Behavior, Animal; Central Nervous System | 2016 |
Protective effect of early prenatal stress on the induction of asthma in adult mice: Sex-specific differences.
Topics: Age Factors; Analysis of Variance; Animals; Anxiety; Asthma; Body Weight; Bronchoalveolar Lavage; Co | 2016 |
Steroid Profiling in Male Wobbler Mouse, a Model of Amyotrophic Lateral Sclerosis.
Topics: 17-Ketosteroids; Adrenal Glands; Amyotrophic Lateral Sclerosis; Androstanols; Animals; Brain; Cortic | 2016 |
Restricting feeding to the active phase in middle-aged mice attenuates adverse metabolic effects of a high-fat diet.
Topics: Activities of Daily Living; Analysis of Variance; Animals; Blood Glucose; Body Weight; Corticosteron | 2016 |
Effect of subchronic corticosterone administration on α
Topics: Animals; Anti-Inflammatory Agents; Clonidine; Corticosterone; Disease Models, Animal; Hypothalamo-Hy | 2016 |
Antidepressant-like effects and cognitive enhancement of the total phenols extract of Hemerocallis citrina Baroni in chronic unpredictable mild stress rats and its related mechanism.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Biogenic Monoamines; Brain-Derived Neurotrophic Fa | 2016 |
Long-lasting monoaminergic and behavioral dysfunctions in a mice model of socio-environmental stress during adolescence.
Topics: Adrenal Glands; Animals; Biogenic Monoamines; Brain; Circadian Rhythm; Corticosterone; Dark Adaptati | 2017 |
Interleukin-18 Reduces Blood Glucose and Modulates Plasma Corticosterone in a Septic Mouse Model.
Topics: Animals; Blood Glucose; Corticosterone; Disease Models, Animal; Glucose-6-Phosphatase; Insulin; Inte | 2017 |
Exposure to alcohol during adolescence exerts long-term effects on stress response and the adult brain stress circuits.
Topics: Animals; Arginine Vasopressin; Brain; Central Nervous System Depressants; Corticosterone; Disease Mo | 2016 |
Investigation of the effects of vanilloids in chronic fatigue syndrome.
Topics: Animals; Anxiety; Brain; Capsaicin; Corticosterone; Disease Models, Animal; Fatigue Syndrome, Chroni | 2016 |
Selective CRF2 receptor agonists ameliorate the anxiety- and depression-like state developed during chronic nicotine treatment and consequent acute withdrawal in mice.
Topics: Animals; Anxiety; Corticosterone; Depression; Disease Models, Animal; Drug Evaluation, Preclinical; | 2016 |
Neuropsin Inactivation Has Protective Effects against Depressive-Like Behaviours and Memory Impairment Induced by Chronic Stress.
Topics: Animals; Corticosterone; Depression; Disease Models, Animal; Glutamic Acid; Hippocampus; Humans; Kal | 2016 |
Acute high-intensity noise induces rapid Arc protein expression but fails to rapidly change GAD expression in amygdala and hippocampus of rats: Effects of treatment with D-cycloserine.
Topics: Amygdala; Animals; Auditory Cortex; Biomarkers; Corticosterone; Cycloserine; Cytoskeletal Proteins; | 2016 |
Scopolamine-induced greater alterations in neurochemical profile and increased oxidative stress demonstrated a better model of dementia: A comparative study.
Topics: Aging; Animals; Avoidance Learning; Brain; Corticosterone; Dementia; Disease Models, Animal; Hippoca | 2016 |
The wake-promoting drug modafinil stimulates specific hypothalamic circuits to promote adaptive stress responses in an animal model of PTSD.
Topics: Adaptation, Psychological; Animals; Arousal; Benzhydryl Compounds; Corticosterone; Disease Models, A | 2016 |
Corticosteroids Mediate Heart Failure-Induced Depression through Reduced σ1-Receptor Expression.
Topics: Adenosine Triphosphate; Administration, Oral; Animals; Aorta; Behavior, Animal; Cardiomegaly; Cortic | 2016 |
Resveratrol Ameliorates the Depressive-Like Behaviors and Metabolic Abnormalities Induced by Chronic Corticosterone Injection.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Blood Glucose; Body Weight; Corticosterone; Depres | 2016 |
Stress and its role in the dentin hypersensitivity in rats.
Topics: Animals; Behavior, Animal; Body Weight; Corticosterone; Dentin Sensitivity; Disease Models, Animal; | 2017 |
Strain and sex based characterization of behavioral expressions in non-induced compulsive-like mice.
Topics: Analysis of Variance; Animals; Corticosterone; Depression; Disease Models, Animal; Enzyme-Linked Imm | 2017 |
Cognitive and behavioural effects induced by social stress plus MDMA administration in mice.
Topics: Analysis of Variance; Animals; Avoidance Learning; Behavioral Symptoms; Body Temperature; Cognition | 2017 |
Exogenous daytime melatonin modulates response of adolescent mice in a repeated unpredictable stress paradigm.
Topics: Age Factors; Animals; Anti-Anxiety Agents; Antioxidants; Behavior, Animal; Biomarkers; Brain; Chroni | 2017 |
The expression of plasticity-related genes in an acute model of stress is modulated by chronic desipramine in a time-dependent manner within medial prefrontal cortex.
Topics: Actin Depolymerizing Factors; Animals; Antidepressive Agents, Tricyclic; Corticosterone; Desipramine | 2017 |
Vibrissal paralysis produces increased corticosterone levels and impairment of spatial memory retrieval.
Topics: Analysis of Variance; Animals; Body Weight; Corticosterone; Disease Models, Animal; Facial Paralysis | 2017 |
Behavioral effects of chronic stress in the Fmr1 mouse model for fragile X syndrome.
Topics: Analysis of Variance; Animals; Behavioral Symptoms; Corticosterone; Disease Models, Animal; Explorat | 2017 |
The habenula as a critical node in chronic stress-related anxiety.
Topics: Animals; Anxiety; Chronic Disease; Corticosterone; Disease Models, Animal; Electrolysis; Habenula; M | 2017 |
Long-term effects of repeated maternal separation and ethanol intake on HPA axis responsiveness in adult rats.
Topics: Adrenocorticotropic Hormone; Alcohol Drinking; Animals; Animals, Newborn; Central Nervous System Dep | 2017 |
Molecular modifications by regulating cAMP signaling and oxidant-antioxidant defence mechanisms, produce antidepressant-like effect: A possible mechanism of etazolate aftermaths of impact accelerated traumatic brain injury in rat model.
Topics: Animals; Antidepressive Agents; Antioxidants; Behavior, Animal; Brain Injuries, Traumatic; Corticost | 2017 |
Stress induces equivalent remodeling of hippocampal spine synapses in a simulated postpartum environment and in a female rat model of major depression.
Topics: Animals; Corticosterone; Depression, Postpartum; Depressive Disorder, Major; Disease Models, Animal; | 2017 |
Antidepressant effect of recombinant NT4-NAP/AAV on social isolated mice through intranasal route.
Topics: Administration, Intranasal; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corticoste | 2017 |
Alterations in splenic function and gene expression in mice with depressive-like behavior induced by exposure to corticosterone.
Topics: Animals; Behavior, Animal; Biomarkers; Cluster Analysis; Corticosterone; Depression; Disease Models, | 2017 |
Impact of Psychological Stress on Pain Perception in an Animal Model of Endometriosis.
Topics: Animals; Anxiety; Corticosterone; Disease Models, Animal; Endometriosis; Enkephalins; Female; Oligop | 2017 |
Anhedonia but not passive floating is an indicator of depressive-like behavior in two chronic stress paradigms.
Topics: Animals; Brain; Corticosterone; Depression; Disease Models, Animal; Electroshock; Exploratory Behavi | 2016 |
Lithium-induced malaise does not interfere with adaptation of the hypothalamic-pituitary-adrenal axis to stress.
Topics: Adaptation, Physiological; Adrenocorticotropic Hormone; Animals; Antimanic Agents; Body Weight; Cort | 2017 |
Neonatal blockade of GABA-A receptors alters behavioral and physiological phenotypes in adult mice.
Topics: Adaptation, Ocular; Age Factors; Animals; Animals, Newborn; Anxiety; Behavior, Animal; Bicuculline; | 2017 |
Conjugated Linoleic Acid Administration Induces Amnesia in Male Sprague Dawley Rats and Exacerbates Recovery from Functional Deficits Induced by a Controlled Cortical Impact Injury.
Topics: Amnesia; Animals; Brain Injuries; Cerebral Cortex; Cognition; Cognitive Dysfunction; Corticosterone; | 2017 |
Safer topical treatment for inflammation using 5α-tetrahydrocorticosterone in mouse models.
Topics: Administration, Topical; Animals; Corticosterone; Disease Models, Animal; Inflammation; Male; Mice; | 2017 |
VEGF promotes cartilage angiogenesis by phospho-ERK1/2 activation of Dll4 signaling in temporomandibular joint osteoarthritis caused by chronic sleep disturbance in Wistar rats.
Topics: Adrenocorticotropic Hormone; Animals; Cartilage; Corticosterone; Disease Models, Animal; Extracellul | 2017 |
Stress biomarker responses to different protocols of forced exercise in chronically stressed rats.
Topics: Animals; Biomarkers; Blood Glucose; Body Weight; Corticosterone; Disease Models, Animal; Interleukin | 2017 |
Experimental occlusal disharmony - A promoting factor for anxiety in rats under chronic psychological stress.
Topics: Analysis of Variance; Animals; Anxiety; Brain; Chronic Disease; Corticosterone; Disease Models, Anim | 2017 |
Chronic social instability increases anxiety-like behavior and ethanol preference in male Long Evans rats.
Topics: Alcohol Drinking; Analysis of Variance; Animals; Anxiety; Corticosterone; Disease Models, Animal; Dr | 2017 |
Mild Social Stress in Mice Produces Opioid-Mediated Analgesia in Visceral but Not Somatic Pain States.
Topics: Acetic Acid; Animals; Capsaicin; Corticosterone; Cues; Disease Models, Animal; Formaldehyde; Male; M | 2017 |
Brief Social Isolation in the Adolescent Wistar-Kyoto Rat Model of Endogenous Depression Alters Corticosterone and Regional Monoamine Concentrations.
Topics: Age Factors; Animals; Biogenic Monoamines; Brain; Corticosterone; Depressive Disorder; Disease Model | 2017 |
Targeting the Microbiota-Gut-Brain Axis: Prebiotics Have Anxiolytic and Antidepressant-like Effects and Reverse the Impact of Chronic Stress in Mice.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Brain; Corticosterone; Depression; Dis | 2017 |
Simvastatin treatment aggravates the glucocorticoid insufficiency associated with hypocholesterolemia in mice.
Topics: Adrenal Cortex Function Tests; Adrenal Glands; Adrenal Insufficiency; Adrenocorticotropic Hormone; A | 2017 |
Chronic unpredictable mild stress paradigm in male Wistar rats: effect on anxiety- and depressive-like behavior.
Topics: Animals; Anxiety; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Male; Rats; | 2016 |
Maternal exposure to low levels of corticosterone during lactation protects adult rat progeny against TNBS-induced colitis: A study on GR-mediated anti-inflammatory effect and prokineticin system.
Topics: Animals; Breast Feeding; Colitis; Corticosterone; Disease Models, Animal; Female; Gastrointestinal H | 2017 |
Tinnitus and hyperacusis: Contributions of paraflocculus, reticular formation and stress.
Topics: Acoustic Stimulation; Animals; Auditory Pathways; Behavior, Animal; Biomarkers; Cerebellum; Corticos | 2017 |
Chronic corticosterone administration effects on behavioral emotionality in female c57bl6 mice.
Topics: Animals; Behavior, Animal; Cell Proliferation; Corticosterone; Depression; Depressive Disorder, Majo | 2017 |
Oral administration of corticosterone at stress-like levels drives microglial but not vascular disturbances post-stroke.
Topics: Administration, Oral; Analysis of Variance; Animals; Anti-Inflammatory Agents; Brain; CD11b Antigen; | 2017 |
Stress induces a switch of intracellular signaling in sensory neurons in a model of generalized pain.
Topics: Adrenalectomy; Analysis of Variance; Animals; Behavior, Animal; Corticosterone; Dinoprostone; Diseas | 2008 |
Effects of Marapuama in the chronic mild stress model: further indication of antidepressant properties.
Topics: Animals; Antidepressive Agents; Corticosterone; Depression; Disease Models, Animal; Dose-Response Re | 2008 |
Stress, geomagnetic disturbance, infradian and circadian sampling for circulating corticosterone and models of human depression?
Topics: Animals; Body Weight; Chronobiology Disorders; Circadian Rhythm; Corticosterone; Depression; Dietary | 2008 |
Antagonism of corticotrophin-releasing factor receptors in the fourth ventricle modifies responses to mild but not restraint stress.
Topics: Animals; Behavior, Animal; Corticosterone; Corticotropin-Releasing Hormone; Disease Models, Animal; | 2008 |
A novel mouse model for acute and long-lasting consequences of early life stress.
Topics: Acute Disease; Age Factors; Animals; Anxiety; Arginine Vasopressin; Chronic Disease; Corticosterone; | 2008 |
Corticosterone and related receptor expression are associated with increased beta-amyloid plaques in isolated Tg2576 mice.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Benzothiazoles | 2008 |
Moderate perinatal arsenic exposure alters neuroendocrine markers associated with depression and increases depressive-like behaviors in adult mouse offspring.
Topics: Analysis of Variance; Animals; Animals, Newborn; Arsenic; Behavior, Animal; Corticosterone; Depressi | 2008 |
Acute episodes of predator exposure in conjunction with chronic social instability as an animal model of post-traumatic stress disorder.
Topics: Animals; Corticosterone; Disease Models, Animal; Male; Maze Learning; Predatory Behavior; Rats; Rats | 2008 |
Global birth hypoxia increases the neonatal testosterone surge in the rat.
Topics: Adrenocorticotropic Hormone; Animals; Animals, Newborn; Behavior, Animal; Cesarean Section; Corticos | 2008 |
An animal model to study health effects during continuous low-dose exposure to the nerve agent VX.
Topics: Acetylcholinesterase; Animals; Blood Pressure; Chemical Warfare Agents; Cholinesterase Inhibitors; C | 2008 |
Chronic unpredictable stress promotes neuronal apoptosis in the cerebral cortex.
Topics: Animals; Antidepressive Agents, Tricyclic; Apoptosis; Caspase 3; Cerebral Cortex; Chronic Disease; C | 2008 |
Early post-stressor intervention with high-dose corticosterone attenuates posttraumatic stress response in an animal model of posttraumatic stress disorder.
Topics: Acoustic Stimulation; Animals; Cats; Corticosterone; Disease Models, Animal; Dose-Response Relations | 2008 |
Psychological stress reactivates dextran sulfate sodium-induced chronic colitis in mice.
Topics: Adrenal Glands; Animals; Avoidance Learning; Chemokine CCL5; Chemokine CXCL1; Colitis; Corticosteron | 2008 |
The effects of corticosterone and beta-endorphin on adherence, phagocytosis and hydrogen peroxide production of macrophages isolated from Dark Agouti rats exposed to acute stress.
Topics: Acute Disease; Animals; beta-Endorphin; Cell Adhesion; Cell Separation; Cells, Cultured; Chemotaxis, | 2008 |
Exogenous corticosterone reduces L-DOPA-induced dyskinesia in the hemi-parkinsonian rat: role for interleukin-1beta.
Topics: Animals; Anti-Inflammatory Agents; Corpus Striatum; Corticosterone; Disease Models, Animal; Dose-Res | 2008 |
Central infusion of aldosterone synthase inhibitor attenuates left ventricular dysfunction and remodelling in rats after myocardial infarction.
Topics: Aldosterone; Animals; Cardiac Catheterization; Corticosterone; Cytochrome P-450 CYP11B2; Disease Mod | 2009 |
The antidepressant agomelatine blocks the adverse effects of stress on memory and enables spatial learning to rapidly increase neural cell adhesion molecule (NCAM) expression in the hippocampus of rats.
Topics: Acetamides; Analysis of Variance; Animals; Antidepressive Agents; Corticosterone; Disease Models, An | 2009 |
The possible use of hypoxic preconditioning for the prophylaxis of post-stress depressive episodes.
Topics: Analysis of Variance; Animals; Atmospheric Pressure; Corticosterone; Depressive Disorder; Disease Mo | 2008 |
Heterogeneity of neuroendocrine stress responses in aging rat strains.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Age Factors; Aging; Analysis of Variance; Animals; Beha | 2009 |
The single-prolonged stress paradigm alters both the morphology and stress response of magnocellular vasopressin neurons.
Topics: Adrenocorticotropic Hormone; Analysis of Variance; Animals; Behavior, Animal; Corticosterone; Dendri | 2008 |
Enhanced stress reactivity in nitric oxide synthase type 2 mutant mice: findings in support of astrocytic nitrosative modulation of behavior.
Topics: Analysis of Variance; Animals; Astrocytes; Behavior, Animal; Corticosterone; Disease Models, Animal; | 2008 |
The effect of chronic variable stress on bowel habit and adrenal function in rats.
Topics: Adrenal Glands; Animals; Body Weight; Chronic Disease; Colon; Corticosterone; Defecation; Disease Mo | 2008 |
Social isolation potentiates cell death and inflammatory responses after global ischemia.
Topics: Animals; Cell Death; Corticosterone; Disease Models, Animal; Fluoresceins; Hypothermia, Induced; Inf | 2008 |
Effect of sub-deficient zinc status on insulin sensitivity after burn injury in rats.
Topics: Animals; Antioxidants; Blood Glucose; Burns; Corticosterone; Diet; Disease Models, Animal; Femur; In | 2009 |
Repeated exposure to stressors do not accelerate atherosclerosis in ApoE-/- mice.
Topics: Animals; Aorta, Thoracic; Apolipoproteins E; Atherosclerosis; Blood Pressure; Body Weight; Chronic D | 2009 |
Nimodipine prior to alcohol withdrawal prevents memory deficits during the abstinence phase.
Topics: Alcohol-Induced Disorders; Alcohols; Analysis of Variance; Animals; Body Weight; Brain; Calcium Chan | 2008 |
Reciprocal affiliation among adolescent rats during a mild group stressor predicts mammary tumors and lifespan.
Topics: Animals; Corticosterone; Disease Models, Animal; Exploratory Behavior; Female; Hypothalamo-Hypophyse | 2008 |
Fetal undernutrition induces overexpression of CRH mRNA and CRH protein in hypothalamus and increases CRH and corticosterone in plasma during postnatal life in the rat.
Topics: Age Factors; Animals; Animals, Newborn; Body Weight; Corticosterone; Corticotropin-Releasing Hormone | 2008 |
Phagocyte migration and cellular stress induced in liver, lung, and intestine during sleep loss and sleep recovery.
Topics: Animals; Cell Movement; Corticosterone; Disease Models, Animal; Heme Oxygenase (Decyclizing); Immuno | 2008 |
Neonatal stress or morphine treatment alters adult mouse conditioned place preference.
Topics: Analgesics, Opioid; Animals; Animals, Newborn; Conditioning, Classical; Corticosterone; Disease Mode | 2009 |
Nicotinic acetylcholine receptor activation mediates nicotine-induced enhancement of experimental periodontitis.
Topics: Alveolar Bone Loss; Animals; Corticosterone; Disease Models, Animal; Disease Susceptibility; Escheri | 2009 |
Exaggerated responses to stress in the BTBR T+tf/J mouse: an unusual behavioral phenotype.
Topics: Animals; Anxiety; Autistic Disorder; Corticosterone; Disease Models, Animal; Enzyme-Linked Immunosor | 2009 |
Alcohol self-administration acutely stimulates the hypothalamic-pituitary-adrenal axis, but alcohol dependence leads to a dampened neuroendocrine state.
Topics: Adrenocorticotropic Hormone; Alcohol-Induced Disorders, Nervous System; Alcoholism; Animals; Central | 2008 |
Remodeling of hippocampal spine synapses in the rat learned helplessness model of depression.
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents, Tricyclic; Biomarkers, Pharmacological; Co | 2009 |
Behavioral stress accelerates plaque pathogenesis in the brain of Tg2576 mice via generation of metabolic oxidative stress.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Aniline Compounds; Animals | 2009 |
Development of alopecia areata is associated with higher central and peripheral hypothalamic-pituitary-adrenal tone in the skin graft induced C3H/HeJ mouse model.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Alopecia Areata; Animals; Corticosterone; Cytokines; Di | 2009 |
Hypophagia induced by glucocorticoid deficiency is associated with an increased activation of satiety-related responses.
Topics: Adrenalectomy; Animals; Arcuate Nucleus of Hypothalamus; Behavior, Animal; Body Weight; Catecholamin | 2009 |
Naltrexone effects on male sexual behavior, corticosterone, and testosterone in stressed male rats.
Topics: Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Cold Temperature; Corticosteron | 2009 |
Prenatal stress reduces postnatal neurogenesis in rats selectively bred for high, but not low, anxiety: possible key role of placental 11beta-hydroxysteroid dehydrogenase type 2.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Animals; Animals, Newborn; Anxiety Disorders; Cell Coun | 2009 |
Both pre- and post-lesion experiential therapy is beneficial in 6-hydroxydopamine dopamine-depleted female rats.
Topics: Animals; Apomorphine; Corticosterone; Disease Models, Animal; Dopamine; Environment; Exploratory Beh | 2009 |
Prostaglandin mediates endotoxaemia-induced hypophagia by activation of pro-opiomelanocortin and corticotrophin-releasing factor neurons in rats.
Topics: Adrenocorticotropic Hormone; alpha-MSH; Animals; Anorexia; Appetite Regulation; Corticosterone; Cort | 2009 |
The role of the galaninergic system in modulating stress-related responses in an animal model of posttraumatic stress disorder.
Topics: Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corticosterone; Coumarins; Disease Mod | 2009 |
Role of central nervous system aldosterone synthase and mineralocorticoid receptors in salt-induced hypertension in Dahl salt-sensitive rats.
Topics: Aldosterone; Animals; Blood Pressure; Corticosterone; Cytochrome P-450 CYP11B2; Disease Models, Anim | 2009 |
Corticosterone regulates pERK1/2 map kinase in a chronic depression model.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Conditioning, O | 2008 |
Increased phospholipase A2 activity and inflammatory response but decreased nerve growth factor expression in the olfactory bulbectomized rat model of depression: effects of chronic ethyl-eicosapentaenoate treatment.
Topics: Analysis of Variance; Animals; Celecoxib; Corticosterone; Corticotropin-Releasing Hormone; Cyclooxyg | 2009 |
Alprazolam treatment immediately after stress exposure interferes with the normal HPA-stress response and increases vulnerability to subsequent stress in an animal model of PTSD.
Topics: Acoustic Stimulation; Alprazolam; Analysis of Variance; Animals; Anti-Anxiety Agents; Behavior, Anim | 2009 |
Involvement of thyroid hormones in the alterations of T-cell immunity and tumor progression induced by chronic stress.
Topics: Animals; Cell Proliferation; Concanavalin A; Corticosterone; Disease Models, Animal; Disease Progres | 2009 |
St. John's Wort modulates brain regional serotonin metabolism in swim stressed rats.
Topics: Amygdala; Animals; Anti-Anxiety Agents; Behavior, Animal; Brain; Corticosterone; Disease Models, Ani | 2009 |
Metabolic consequences and vulnerability to diet-induced obesity in male mice under chronic social stress.
Topics: Adipose Tissue; Aggression; Animals; Body Weight; Corticosterone; Diet; Dietary Fats; Disease Models | 2009 |
Uteroplacental insufficiency affects kidney VEGF expression in a model of IUGR with compensatory glomerular hypertrophy and hypertension.
Topics: Animals; Animals, Newborn; Base Sequence; Corticosterone; Creatinine; Disease Models, Animal; DNA Pr | 2009 |
Colonic bacterial translocation as a possible factor in stress-worsening experimental stroke outcome.
Topics: Animals; Anti-Bacterial Agents; Bacterial Translocation; Colitis; Colon; Corticosterone; Cyclooxygen | 2009 |
SK2 potassium channel overexpression in basolateral amygdala reduces anxiety, stress-induced corticosterone secretion and dendritic arborization.
Topics: Amygdala; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Corticosterone; Dendrites; Disea | 2009 |
11beta-hydroxysteroid dehydrogenases are regulated during the pulmonary granulomatous response to the mycobacterial glycolipid trehalose-6,6'-dimycolate.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Animals; C | 2009 |
Methylenedioxymethamphetamine (Ecstasy) decreases neutrophil activity and alters leukocyte distribution in bone marrow, spleen and blood.
Topics: Animals; Bone Marrow Cells; Corticosterone; Disease Models, Animal; Hallucinogens; Hypothalamo-Hypop | 2009 |
Antidepressant-like effects of melatonin in the mouse chronic mild stress model.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Chronic Disease; Circadian Rhythm; Corticosterone; | 2009 |
Distinct effects of acute and chronic sleep loss on DNA damage in rats.
Topics: Analysis of Variance; Animals; Brain; Comet Assay; Corticosterone; Disease Models, Animal; DNA Damag | 2009 |
Disengaging insulin from corticosterone: roles of each on energy intake and disposition.
Topics: Adrenalectomy; Animals; Arcuate Nucleus of Hypothalamus; Body Weight; Corticosterone; Diabetes Melli | 2009 |
Chronic blockade of hindbrain glucocorticoid receptors reduces blood pressure responses to novel stress and attenuates adaptation to repeated stress.
Topics: Adaptation, Physiological; Animals; Blood Pressure; Body Weight; Corticosterone; Disease Models, Ani | 2009 |
Elevated plasma corticosterone level and depressive behavior in experimental temporal lobe epilepsy.
Topics: Animals; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Electrodes, Implanted | 2009 |
Stress is critical for LPS-induced activation of microglia and damage in the rat hippocampus.
Topics: Animals; Arachidonic Acids; Body Weight; Brain-Derived Neurotrophic Factor; Cell Count; Corticostero | 2011 |
Antidepressant-like effects of curcumin on serotonergic receptor-coupled AC-cAMP pathway in chronic unpredictable mild stress of rats.
Topics: Adenylyl Cyclases; Analysis of Variance; Animals; Antidepressive Agents; Body Weight; Brain; Cortico | 2009 |
Exenatide improves hypertension in a rat model of the metabolic syndrome.
Topics: Animals; Blood Pressure; Body Weight; Corticosterone; Disease Models, Animal; Exenatide; Glucagon-Li | 2009 |
Chronic social instability stress in female rats: a potential animal model for female depression.
Topics: Adrenal Glands; Animals; Body Temperature Regulation; Corticosterone; Depressive Disorder; Disease M | 2009 |
Transient forebrain over-expression of CRF induces plasma corticosterone and mild behavioural changes in adult conditional CRF transgenic mice.
Topics: Animals; Anxiety; Base Sequence; Behavior, Animal; Corticosterone; Corticotropin-Releasing Hormone; | 2009 |
Gender-specific impact of brain-derived neurotrophic factor signaling on stress-induced depression-like behavior.
Topics: Analysis of Variance; Animals; Body Weight; Brain-Derived Neurotrophic Factor; Corticosterone; Depre | 2009 |
Amygdaloid pERK1/2 in corticotropin-releasing hormone overexpressing mice under basal and acute stress conditions.
Topics: Amphibian Proteins; Amygdala; Animals; Autoradiography; Corticosterone; Corticotropin-Releasing Horm | 2009 |
Affect-related behaviors in mice misexpressing the RNA editing enzyme ADAR2.
Topics: Adenosine Deaminase; Affective Symptoms; Analysis of Variance; Animals; Behavior, Animal; Body Weigh | 2009 |
Occlusal disharmony increases stress response in rats.
Topics: Animals; Corticosterone; Dental Occlusion; Disease Models, Animal; Feedback; Hypothalamo-Hypophyseal | 2009 |
Glucocorticoid receptor and mitogen-activated protein kinase activity after restraint stress and acoustic trauma.
Topics: Animals; Cochlea; Cochlear Nerve; Corticosterone; Disease Models, Animal; Down-Regulation; Hearing L | 2009 |
Transgenic Alzheimer mice in a semi-naturalistic environment: more plaques, yet not compromised in daily life.
Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Behavior, A | 2009 |
Preventive action of Kai Xin San aqueous extract on depressive-like symptoms and cognition deficit induced by chronic mild stress.
Topics: Acetylcholinesterase; Acorus; Adrenocorticotropic Hormone; Animals; Chronic Disease; Cognition Disor | 2009 |
Ketamine treatment reverses behavioral and physiological alterations induced by chronic mild stress in rats.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Behavior, Animal; Corticosterone; Disease Mode | 2009 |
Effects of prenatal immune activation on hippocampal neurogenesis in the rat.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroida | 2009 |
A distinct pattern of intracellular glucocorticoid-related responses is associated with extreme behavioral response to stress in an animal model of post-traumatic stress disorder.
Topics: Analysis of Variance; Animals; Brain; Cats; Corticosterone; Disease Models, Animal; Early Growth Res | 2009 |
Dissecting the pathophysiology of depression with a Swiss army knife.
Topics: Animals; Corticosterone; Depression; Disease Models, Animal; Fluoxetine; Hippocampus; Humans; Neurog | 2009 |
Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Anxiety; Arrestins; beta-Ar | 2009 |
Mouse model of fragile X syndrome: behavioral and hormonal response to stressors.
Topics: Animals; Association Learning; Avoidance Learning; Conditioning, Psychological; Corticosterone; Dise | 2009 |
Time-dependent alterations of peripheral immune parameters after nigrostriatal dopamine depletion in a rat model of Parkinson's disease.
Topics: Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Cell Count; Corpus Striatum; Corticoste | 2009 |
Mineralocorticoid receptor overexpression in basolateral amygdala reduces corticosterone secretion and anxiety.
Topics: Amygdala; Animals; Anxiety; Corticosterone; Disease Models, Animal; Gene Expression Regulation; Gene | 2009 |
Morphological reorganization after repeated corticosterone administration in the hippocampus, nucleus accumbens and amygdala in the rat.
Topics: Amygdala; Animals; Anti-Inflammatory Agents; Cell Shape; Corticosterone; Dendrites; Dendritic Spines | 2009 |
Acute stress affects the physiology and behavior of allergic mice.
Topics: Animals; Bronchoalveolar Lavage Fluid; Corticosterone; Cytotoxicity, Immunologic; Disease Models, An | 2009 |
Neuroendocrine and neurochemical impact of aggressive social interactions in submissive and dominant mice: implications for stress-related disorders.
Topics: Aggression; Analysis of Variance; Animals; Behavior, Animal; Biogenic Monoamines; Brain; Corticoster | 2010 |
Plasma adiponectin levels are increased despite insulin resistance in corticotropin-releasing hormone transgenic mice, an animal model of Cushing syndrome.
Topics: Adiponectin; Animals; Corticosterone; Corticotropin-Releasing Hormone; Cushing Syndrome; Disease Mod | 2009 |
"Green odor" inhalation by rats down-regulates stress-induced increases in Fos expression in stress-related forebrain regions.
Topics: Administration, Inhalation; Aldehydes; Amygdala; Animals; Biomarkers; Cell Count; Corticosterone; Di | 2009 |
Transgenic disruption of glucocorticoid signaling in mature osteoblasts and osteocytes attenuates K/BxN mouse serum-induced arthritis in vivo.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adrenocorticotropic Hormone; Animals; Arthritis; Autoim | 2009 |
Predictable stress versus unpredictable stress: a comparison in a rodent model of stroke.
Topics: Adrenal Glands; Animals; Corticosterone; Disease Models, Animal; Male; Motor Cortex; Motor Skills; O | 2009 |
Reduced emotional and corticosterone responses to stress in mu-opioid receptor knockout mice.
Topics: Analysis of Variance; Animals; Corticosterone; Disease Models, Animal; Emotions; Female; Hindlimb Su | 2010 |
Peony glycosides produce antidepressant-like action in mice exposed to chronic unpredictable mild stress: effects on hypothalamic-pituitary-adrenal function and brain-derived neurotrophic factor.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Conditionin | 2009 |
Hypothermic responses to infection are inhibited by alpha2-adrenoceptor agonists with possible clinical implications.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Bacterial Infections; Body | 2009 |
An animal model of testicular toxicity by cyclosporine: evaluation and protection.
Topics: Animals; Corticosterone; Cyclosporine; Disease Models, Animal; Dose-Response Relationship, Drug; Imm | 2009 |
Susceptibility to stress in transgenic mice overexpressing TrkC, a model of panic disorder.
Topics: Animals; Anxiety; Behavior, Animal; Circadian Rhythm; Corticosterone; Disease Models, Animal; Geneti | 2010 |
Maternal care and selection for low mortality affect post-stress corticosterone and peripheral serotonin in laying hens.
Topics: Animals; Behavior, Animal; Blood Platelets; Chickens; Corticosterone; Disease Models, Animal; Female | 2009 |
Depressive-like parameters in sepsis survivor rats.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Analysis of Variance; Animals; Antidepressive Agents, T | 2010 |
Antidepressant-like effects of rosiglitazone, a PPARγ agonist, in the rat forced swim and mouse tail suspension tests.
Topics: Anilides; Animals; Antidepressive Agents; Corticosterone; Depressive Disorder; Disease Models, Anima | 2009 |
Identifying emotional adaptation: behavioural habituation to novelty and immediate early gene expression in two inbred mouse strains.
Topics: Adaptation, Psychological; Animals; Anxiety; Anxiety Disorders; Cognition; Color; Corticosterone; Di | 2010 |
Diet-induced obesity alters behavior as well as serum levels of corticosterone in F344 rats.
Topics: Aggression; Analysis of Variance; Animals; Anxiety; Body Weight; Corticosterone; Diet; Disease Model | 2009 |
Stress and IL-1beta contribute to the development of depressive-like behavior following peripheral nerve injury.
Topics: Analysis of Variance; Animals; Corticosterone; Cytokines; Depression; Disease Models, Animal; Explor | 2010 |
DNA methylation in vulnerability to post-traumatic stress in rats: evidence for the role of the post-synaptic density protein Dlgap2.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Behavior, Animal; Computational Biology; Cortic | 2010 |
Sexually dimorphic response of the hypothalamo-pituitary-adrenal axis to chronic alcohol consumption and withdrawal.
Topics: Alcohol-Induced Disorders, Nervous System; Alcoholism; Animals; Cell Death; Chronic Disease; Cortico | 2009 |
Recapitulation and reversal of a persistent depression-like syndrome in rodents.
Topics: Animals; Anti-Inflammatory Agents; Chronic Disease; Corticosterone; Cyclic AMP Response Element-Bind | 2009 |
Maternal separation alters nerve growth factor and corticosterone levels but not the DNA methylation status of the exon 1(7) glucocorticoid receptor promoter region.
Topics: Animals; Base Sequence; Behavior, Animal; Corticosterone; Disease Models, Animal; DNA Methylation; E | 2009 |
The lonely mouse: verification of a separation-induced model of depression in female mice.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Conditioning, Classi | 2010 |
Cerebrovascular cyclooxygenase-1 expression, regulation, and role in hypothalamic-pituitary-adrenal axis activation by inflammatory stimuli.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Cyclooxygenase 1; Cyclooxygenase Inhibitors; D | 2009 |
High susceptibility to chronic social stress is associated with a depression-like phenotype.
Topics: Animals; Anxiety; Behavior, Animal; Body Weight; Brain; Corticosterone; Corticotropin-Releasing Horm | 2010 |
Dissociation of local anti-inflammatory effect and systemic effects of mometasone furoate in mice.
Topics: Administration, Oral; Administration, Topical; Animals; Anti-Inflammatory Agents; Beclomethasone; Co | 2009 |
Long-term postpartum anxiety and depression-like behavior in mother rats subjected to maternal separation are ameliorated by palatable high fat diet.
Topics: Adipose Tissue; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Anxiety; Body Weight; | 2010 |
Effect of imipramine on nerve excitability in GC rats.
Topics: Administration, Oral; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Catatonia; Cortic | 2009 |
Fetal adrenal gland alterations in a rat model of adverse intrauterine environment.
Topics: Adrenal Glands; Aldosterone; Animals; Cardiomegaly; Corticosterone; Disease Models, Animal; DNA Prim | 2010 |
Effects of acute cold stress on phagocytosis of apoptotic cells: the role of corticosterone.
Topics: Acute Disease; Animals; Apoptosis; Catecholamines; Cold Temperature; Corticosterone; Disease Models, | 2010 |
Susceptibility to stress in young rats after 2-week zinc deprivation.
Topics: Animals; Brain Chemistry; Corticosterone; Depressive Disorder; Dietary Supplements; Disease Models, | 2010 |
Circadian phase and sex effects on depressive/anxiety-like behaviors and HPA axis responses to acute stress.
Topics: Animals; Anxiety; Circadian Rhythm; Corticosterone; Depression; Disease Models, Animal; Female; Hypo | 2010 |
Palatable cafeteria diet ameliorates anxiety and depression-like symptoms following an adverse early environment.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Anxiety; Corticosterone; Corticotropin-Releasi | 2010 |
Presence of conspecifics and their odor-impregnated objects reverse stress-decreased neurogenesis in mouse dentate gyrus.
Topics: Analysis of Variance; Animals; Bromodeoxyuridine; Cell Differentiation; Cell Proliferation; Corticos | 2010 |
Nerve growth factor (NGF) has novel antidepressant-like properties in rats.
Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Brain; Corticos | 2010 |
In vitro and in vivo characterization of JNJ-31020028 (N-(4-{4-[2-(diethylamino)-2-oxo-1-phenylethyl]piperazin-1-yl}-3-fluorophenyl)-2-pyridin-3-ylbenzamide), a selective brain penetrant small molecule antagonist of the neuropeptide Y Y(2) receptor.
Topics: Administration, Oral; Animals; Anorexia; Anti-Anxiety Agents; Anxiety; Autoradiography; Benzamides; | 2010 |
Fetal asphyctic preconditioning protects against perinatal asphyxia-induced behavioral consequences in adulthood.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Asphyxia Neonatorum; Behavioral Sympto | 2010 |
Chronic hyperammonemia alters the circadian rhythms of corticosteroid hormone levels and of motor activity in rats.
Topics: Adrenal Cortex Hormones; Animals; Body Temperature; Brain; Brain Chemistry; Chronic Disease; Circadi | 2010 |
Prenatal thyroxine treatment disparately affects peripheral and amygdala thyroid hormone levels.
Topics: Amygdala; Animals; Anxiety; Corticosterone; Corticotropin-Releasing Hormone; Depressive Disorder; Di | 2010 |
Nicotine self-administration diminishes stress-induced norepinephrine secretion but augments adrenergic-responsiveness in the hypothalamic paraventricular nucleus and enhances adrenocorticotropic hormone and corticosterone release.
Topics: Adrenergic Agents; Adrenocorticotropic Hormone; Animals; Chromatography, High Pressure Liquid; Corti | 2010 |
Increased stress reactivity is associated with cognitive deficits and decreased hippocampal brain-derived neurotrophic factor in a mouse model of affective disorders.
Topics: Analysis of Variance; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cognition Disord | 2010 |
Mild postnatal separation stress reduces repeated stress-induced immunosuppression in adult BALB/c mice.
Topics: Acoustic Stimulation; Age Factors; Animals; Animals, Newborn; Anxiety, Separation; Apoptosis; Body W | 2009 |
Ambiguous-cue interpretation is biased under stress- and depression-like states in rats.
Topics: Adrenergic Uptake Inhibitors; Amygdala; Analysis of Variance; Animals; Behavior, Animal; Bias; Condi | 2010 |
The whisker nuisance task identifies a late-onset, persistent sensory sensitivity in diffuse brain-injured rats.
Topics: Animals; Brain Injuries; Corticosterone; Diffuse Axonal Injury; Disability Evaluation; Disease Model | 2010 |
Colitis causes delay in puberty in female mice out of proportion to changes in leptin and corticosterone.
Topics: Animals; Colitis; Corticosterone; Dextran Sulfate; Disease Models, Animal; Female; Hypothalamo-Hypop | 2010 |
A preliminary report on the effects of sustained administration of corticosteroid on traumatized disc using the adult male rat model.
Topics: Animals; Anti-Inflammatory Agents; Biocompatible Materials; Calcium Phosphates; Cell Count; Chondroc | 2009 |
Food intake during the normal activity phase prevents obesity and circadian desynchrony in a rat model of night work.
Topics: Animals; Behavior, Animal; Body Temperature; Body Weight; Circadian Rhythm; Corticosterone; Disease | 2010 |
The 5-HT(7) receptor as a mediator and modulator of antidepressant-like behavior.
Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Aripiprazole; Citalopram; Corticosterone; Depr | 2010 |
Repeated anabolic androgenic steroid treatment causes antidepressant-reversible alterations of the hypothalamic-pituitary-adrenal axis, BDNF levels and behavior.
Topics: Anabolic Agents; Androgens; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Brain; Brai | 2010 |
Susceptibility of a potential animal model for pathological anxiety to chronic mild stress.
Topics: Analysis of Variance; Animals; Anxiety; Avoidance Learning; Behavior, Animal; Brain; Cell Count; Cor | 2010 |
Endogenous glucocorticoids improve myelination via Schwann cells after peripheral nerve injury: An in vivo study using a crush injury model.
Topics: Adrenalectomy; Analysis of Variance; Animals; Corticosterone; Disease Models, Animal; Dose-Response | 2010 |
Macrophage migration inhibitory factor is critically involved in basal and fluoxetine-stimulated adult hippocampal cell proliferation and in anxiety, depression, and memory-related behaviors.
Topics: Acoustic Stimulation; Animals; Antidepressive Agents, Second-Generation; Anxiety; Bromodeoxyuridine; | 2011 |
Interactions between age, stress and insulin on cognition: implications for Alzheimer's disease.
Topics: Aging; Amyloid beta-Peptides; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Cognitio | 2010 |
Intermittent access to sucrose increases sucrose-licking activity and attenuates restraint stress-induced activation of the lateral septum.
Topics: Animals; Anorexia; Caloric Restriction; Corticosterone; Disease Models, Animal; Drinking; Feeding Be | 2010 |
Nicotine self-administration differentially modulates glutamate and GABA transmission in hypothalamic paraventricular nucleus to enhance the hypothalamic-pituitary-adrenal response to stress.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Disease Models, Animal; Electric Stimulation; | 2010 |
Endocrine and physiological changes in response to chronic corticosterone: a potential model of the metabolic syndrome in mouse.
Topics: Adipose Tissue, White; Adiposity; Adrenal Glands; Animals; Atrophy; Chemical Phenomena; Corticostero | 2010 |
The suitability of 129SvEv mice for studying depressive-like behaviour: both males and females develop learned helplessness.
Topics: Analysis of Variance; Animals; Behavior, Animal; Behavioral Research; Corticosterone; Depression; Di | 2010 |
The novel antidepressant agomelatine normalizes hippocampal neuronal activity and promotes neurogenesis in chronically stressed rats.
Topics: Acetamides; Adrenocorticotropic Hormone; Analysis of Variance; Animals; Antidepressive Agents; Body | 2010 |
Corticosteroid and neurosteroid dysregulation in an animal model of autism, BTBR mice.
Topics: 5-alpha-Dihydroprogesterone; Animals; Autistic Disorder; Brain; Cerebellum; Corticosterone; Disease | 2010 |
Acute and repeated stress differentially regulates behavioral, endocrine, neural parameters relevant to emotional and stress response in young and aged rats.
Topics: Acute Disease; Adaptation, Physiological; Adaptation, Psychological; Aging; Analysis of Variance; An | 2010 |
Pharmacodynamic and pharmacokinetic characterization of the aldosterone synthase inhibitor FAD286 in two rodent models of hyperaldosteronism: comparison with the 11beta-hydroxylase inhibitor metyrapone.
Topics: Adrenal Glands; Aldosterone; Animals; Blood Pressure; Blood Proteins; Chromatography, Liquid; Cortic | 2010 |
Influence of aging on the sleep rebound induced by immobilization stress in the rat.
Topics: Adrenocorticotropic Hormone; Aging; Animals; Corticosterone; Corticotropin-Like Intermediate Lobe Pe | 2010 |
Synergistic effects of age and stress in a rodent model of stroke.
Topics: Age Factors; Animals; Corticosterone; Disease Models, Animal; Exploratory Behavior; Male; Motor Cort | 2010 |
Modeling psychotic and cognitive symptoms of affective disorders: Disrupted latent inhibition and reversal learning deficits in highly stress reactive mice.
Topics: Affective Symptoms; Animals; Avoidance Learning; Brain; Cognition; Corticosterone; Depressive Disord | 2010 |
Resistance to the development of stress-induced behavioral despair in the forced swim test associated with elevated hippocampal Bcl-xl expression.
Topics: Adrenocorticotropic Hormone; Animals; bcl-2-Associated X Protein; bcl-X Protein; Brain-Derived Neuro | 2010 |
Exercise effects on motor and affective behavior and catecholamine neurochemistry in the MPTP-lesioned mouse.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Anxiety; Behavior, Animal; Brain; Corticoster | 2010 |
Prenatal stress potentiates pilocarpine-induced epileptic behaviors in infant rats both time and sex dependently.
Topics: Analysis of Variance; Animals; Animals, Newborn; Corticosterone; Disease Models, Animal; Epilepsy; F | 2010 |
Stress within the postseizure time window inhibits seizure recurrence.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Anticonvulsants; Circadian Rhythm; Corticos | 2010 |
Improved heart function follows enhanced inflammatory cell recruitment and angiogenesis in 11betaHSD1-deficient mice post-MI.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Chemokine CCL2; Corticosterone; Disease Models | 2010 |
Elevated corticosterone levels in stomach milk, serum, and brain of male and female offspring after maternal corticosterone treatment in the rat.
Topics: Animals; Brain; Corticosterone; Depression, Postpartum; Disease Models, Animal; Female; Hypothalamo- | 2010 |
Opposite roles of dopamine and orexin in quinpirole-induced excessive drinking: a rat model of psychotic polydipsia.
Topics: Animals; Benzoxazoles; Cerebral Cortex; Conditioning, Operant; Corticosterone; Disease Models, Anima | 2010 |
Effects of stress in early life on immune functions in rats with asthma and the effects of music therapy.
Topics: Age Factors; Animals; Animals, Newborn; Asthma; Bronchial Hyperreactivity; Corticosterone; Cytokines | 2010 |
Adolescent activity-based anorexia increases anxiety-like behavior in adulthood.
Topics: Age Factors; Amygdala; Animals; Animals, Newborn; Anorexia; Anxiety; Behavior, Animal; Body Weight; | 2010 |
gamma-Aminobutyric acid-type A receptor deficits cause hypothalamic-pituitary-adrenal axis hyperactivity and antidepressant drug sensitivity reminiscent of melancholic forms of depression.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depr | 2010 |
Early-life stress and antidepressants modulate peripheral biomarkers in a gene-environment rat model of depression.
Topics: Animals; Biomarkers; Brain-Derived Neurotrophic Factor; C-Reactive Protein; Citalopram; Corticostero | 2010 |
Chronic corticosterone administration down-regulates metabotropic glutamate receptor 5 protein expression in the rat hippocampus.
Topics: Animals; Anti-Inflammatory Agents; Chronic Disease; Corticosterone; Depressive Disorder, Major; Dise | 2010 |
Chronological assessment of mast cell-mediated gut dysfunction and mucosal inflammation in a rat model of chronic psychosocial stress.
Topics: Animals; Cell Count; Colon; Corticosterone; Corticotropin-Releasing Hormone; Crowding; Disease Model | 2010 |
Sleep disruption aggravates focal cerebral ischemia in the rat.
Topics: Analysis of Variance; Animals; Body Weight; Brain Ischemia; Corticosterone; Disease Models, Animal; | 2010 |
Enhanced fear recall and emotional arousal in rats recovering from chronic variable stress.
Topics: Analysis of Variance; Animals; Arousal; Chronic Disease; Cohort Studies; Conditioning, Psychological | 2010 |
Effects of corticosterone synthesis inhibitor metyrapone on anxiety-related behaviors in Lurcher mutant mice.
Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Cerebellum; Corticosterone; Disease Models | 2010 |
Varying perceived social threat modulates pain behavior in male mice.
Topics: Animals; Behavior, Animal; Castration; Corticosterone; Disease Models, Animal; Feces; Female; Gonada | 2011 |
Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression.
Topics: Animals; Antidepressive Agents; Arginine Vasopressin; Behavior, Animal; Bifidobacterium; Biogenic Mo | 2010 |
Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression.
Topics: Animals; Antidepressive Agents; Arginine Vasopressin; Behavior, Animal; Bifidobacterium; Biogenic Mo | 2010 |
Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression.
Topics: Animals; Antidepressive Agents; Arginine Vasopressin; Behavior, Animal; Bifidobacterium; Biogenic Mo | 2010 |
Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression.
Topics: Animals; Antidepressive Agents; Arginine Vasopressin; Behavior, Animal; Bifidobacterium; Biogenic Mo | 2010 |
Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression.
Topics: Animals; Antidepressive Agents; Arginine Vasopressin; Behavior, Animal; Bifidobacterium; Biogenic Mo | 2010 |
Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression.
Topics: Animals; Antidepressive Agents; Arginine Vasopressin; Behavior, Animal; Bifidobacterium; Biogenic Mo | 2010 |
Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression.
Topics: Animals; Antidepressive Agents; Arginine Vasopressin; Behavior, Animal; Bifidobacterium; Biogenic Mo | 2010 |
Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression.
Topics: Animals; Antidepressive Agents; Arginine Vasopressin; Behavior, Animal; Bifidobacterium; Biogenic Mo | 2010 |
Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression.
Topics: Animals; Antidepressive Agents; Arginine Vasopressin; Behavior, Animal; Bifidobacterium; Biogenic Mo | 2010 |
Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression.
Topics: Animals; Antidepressive Agents; Arginine Vasopressin; Behavior, Animal; Bifidobacterium; Biogenic Mo | 2010 |
Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression.
Topics: Animals; Antidepressive Agents; Arginine Vasopressin; Behavior, Animal; Bifidobacterium; Biogenic Mo | 2010 |
Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression.
Topics: Animals; Antidepressive Agents; Arginine Vasopressin; Behavior, Animal; Bifidobacterium; Biogenic Mo | 2010 |
Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression.
Topics: Animals; Antidepressive Agents; Arginine Vasopressin; Behavior, Animal; Bifidobacterium; Biogenic Mo | 2010 |
Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression.
Topics: Animals; Antidepressive Agents; Arginine Vasopressin; Behavior, Animal; Bifidobacterium; Biogenic Mo | 2010 |
Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression.
Topics: Animals; Antidepressive Agents; Arginine Vasopressin; Behavior, Animal; Bifidobacterium; Biogenic Mo | 2010 |
Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression.
Topics: Animals; Antidepressive Agents; Arginine Vasopressin; Behavior, Animal; Bifidobacterium; Biogenic Mo | 2010 |
Evidence of female-specific glial deficits in the hippocampus in a mouse model of prenatal stress.
Topics: Animals; Anxiety; Behavior, Animal; Cognition; Corticosterone; Depression; Disease Models, Animal; F | 2011 |
The effects of Sceletium tortuosum in an in vivo model of psychological stress.
Topics: Aizoaceae; Animals; Behavior, Animal; C-Reactive Protein; Corticosterone; Disease Models, Animal; In | 2011 |
The effects of repeated social interaction stress on behavioural and physiological parameters in a stress-sensitive mouse strain.
Topics: Adaptation, Physiological; Analysis of Variance; Animals; Colon; Corticosterone; Cytokines; Disease | 2011 |
Mesolimbic dopaminergic activity responding to acute stress is blunted in adolescent rats that experienced neonatal maternal separation.
Topics: Analysis of Variance; Animals; Animals, Newborn; Chromatography, High Pressure Liquid; Corticosteron | 2010 |
Reelin as a putative vulnerability factor for depression: examining the depressogenic effects of repeated corticosterone in heterozygous reeler mice.
Topics: Animals; Anti-Inflammatory Agents; Behavior, Animal; Brain; Cell Adhesion Molecules, Neuronal; Corti | 2011 |
The threshold of insulin-induced hypophagia is lower in chicks selected for low rather than high juvenile body weight.
Topics: Age Factors; Animals; Appetite Regulation; Blood Glucose; Body Weight; Chickens; Corticosterone; Dis | 2011 |
Separating the contribution of glucocorticoids and wakefulness to the molecular and electrophysiological correlates of sleep homeostasis.
Topics: Adrenalectomy; Animals; Circadian Rhythm Signaling Peptides and Proteins; Corticosterone; Disease Mo | 2010 |
Antidepressant-like effect of mitragynine isolated from Mitragyna speciosa Korth in mice model of depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal | 2011 |
Chromosomal mapping of pancreatic islet morphological features and regulatory hormones in the spontaneously diabetic (Type 2) Goto-Kakizaki rat.
Topics: Animals; Blood Glucose; Chromosome Mapping; Corticosterone; Crosses, Genetic; Diabetes Mellitus, Typ | 2010 |
Low stress reactivity and neuroendocrine factors in the BTBR T+tf/J mouse model of autism.
Topics: Adaptation, Ocular; Animals; Autistic Disorder; Corticosterone; Corticotropin-Releasing Hormone; Dis | 2010 |
Chronic antidepressant administration alleviates frontal and hippocampal BDNF deficits in CUMS rat.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Cort | 2010 |
Impaired emotional-like behavior and serotonergic function during protracted abstinence from chronic morphine.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Disease Models, Animal; Drug Evaluation, Precl | 2011 |
Long-term development of excessive and inflexible nicotine taking by rats, effects of a novel treatment approach.
Topics: Administration, Oral; Animals; Behavior, Animal; Body Weight; Choice Behavior; Conditioning, Operant | 2011 |
Behavioral characterization of A/J and C57BL/6J mice using a multidimensional test: association between blood plasma and brain magnesium-ion concentration with anxiety.
Topics: Analysis of Variance; Animals; Anxiety; Avoidance Learning; Behavior, Animal; Brain; Cholesterol; Co | 2011 |
Obesity/hyperleptinemic phenotype adversely affects hippocampal plasticity: effects of dietary restriction.
Topics: Adiposity; Animals; Area Under Curve; Autoradiography; Body Weight; Corticosterone; Disease Models, | 2011 |
A time for learning and a time for sleep: the effect of sleep deprivation on contextual fear conditioning at different times of the day.
Topics: Animals; Circadian Rhythm; Conditioning, Psychological; Corticosterone; Discrimination Learning; Dis | 2010 |
Corticosterone mediates reciprocal changes in CB 1 and TRPV1 receptors in primary sensory neurons in the chronically stressed rat.
Topics: Animals; Benzoxazines; Chronic Disease; Colon; Corticosterone; Disease Models, Animal; Feces; Gangli | 2011 |
Stress and epilepsy: multiple models, multiple outcomes.
Topics: Adrenocorticotropic Hormone; Animals; Brain; Corticosterone; Corticotropin-Releasing Hormone; Diseas | 2010 |
Vulnerability to chronic subordination stress-induced depression-like disorders in adult 129SvEv male mice.
Topics: Aggression; Animals; Anxiety; Chronic Disease; Corticosterone; Depression; Disease Models, Animal; D | 2011 |
Coping with sleep deprivation: shifts in regional brain activity and learning strategy.
Topics: Adaptation, Psychological; Animals; Behavior, Animal; Biomarkers; Brain; Corpus Striatum; Corticoste | 2010 |
LXRβ is required for glucocorticoid-induced hyperglycemia and hepatosteatosis in mice.
Topics: Animals; Base Sequence; Corticosterone; Dexamethasone; Disease Models, Animal; DNA Primers; Drug Des | 2011 |
Prenatal interaction of mutant DISC1 and immune activation produces adult psychopathology.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Animals, Newborn; Atrophy; Behavior, Animal | 2010 |
Cage mate separation in pair-housed male rats evokes an acute stress corticosterone response.
Topics: Animals; Corticosterone; Disease Models, Animal; Housing, Animal; Male; Rats; Rats, Wistar; Social I | 2011 |
Individual stress vulnerability is predicted by short-term memory and AMPA receptor subunit ratio in the hippocampus.
Topics: Animals; Corticosterone; Depressive Disorder, Major; Disease Models, Animal; Female; Gene Expression | 2010 |
Protective effects of flavonoid extract from Apocynum venetum leaves against corticosterone-induced neurotoxicity in PC12 cells.
Topics: Animals; Apocynum; Calcium; Corticosterone; Depression; Disease Models, Animal; Flavonoids; L-Lactat | 2011 |
Traits of the metabolic syndrome alter corpulent obesity in LAN, SHR and DSS rats: behavioral and metabolic interactions with adrenalectomy.
Topics: Adipose Tissue; Adrenalectomy; Analysis of Variance; Animals; Behavior, Animal; Body Composition; Bo | 2011 |
Phenotypic characterization of a genetically diverse panel of mice for behavioral despair and anxiety.
Topics: Animals; Anxiety; Behavior, Animal; Brain; Brain Mapping; Corticosterone; Depression; Disease Models | 2010 |
Early-stress regulates resilience, vulnerability and experimental validity in laboratory rodents through mother-offspring hormonal transfer.
Topics: Animals; Animals, Newborn; Corticosterone; Disease Models, Animal; Disease Susceptibility; Hypothala | 2011 |
Neonatal corticosterone administration impairs adult eyeblink conditioning and decreases glucocorticoid receptor expression in the cerebellar interpositus nucleus.
Topics: Aging; Animals; Animals, Newborn; Cerebellar Nuclei; Conditioning, Eyelid; Corticosterone; Disease M | 2011 |
A role for glucocorticoid-signaling in depression-like behavior of gastrin-releasing peptide receptor knock-out mice.
Topics: Amygdala; Animals; Behavior, Animal; Corticosterone; Depression; Dexamethasone; Disease Models, Anim | 2011 |
Icariin attenuates social defeat-induced down-regulation of glucocorticoid receptor in mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal | 2011 |
Chronic stress prior to hippocampal stroke enhances post-stroke spatial deficits in the ziggurat task.
Topics: Animals; Chronic Disease; Corticosterone; Disease Models, Animal; Endothelin-1; Glucocorticoids; Hip | 2011 |
"Snacking" causes long term attenuation of HPA axis stress responses and enhancement of brain FosB/deltaFosB expression in rats.
Topics: Animals; Body Weight; Corticosterone; Disease Models, Animal; Eating; Hypothalamo-Hypophyseal System | 2011 |
Hypericum perforatum treatment: effect on behaviour and neurogenesis in a chronic stress model in mice.
Topics: Animals; Anxiety; Behavior, Animal; Cell Proliferation; Corticosterone; Dendrites; Depression; Disea | 2011 |
Old mice lacking high-affinity nicotine receptors resist acoustic trauma.
Topics: Age Factors; Aging; Animals; Auditory Pathways; Cochlear Nucleus; Corticosterone; Cytoprotection; Di | 2011 |
Neurochemical, hormonal, and behavioral effects of chronic unpredictable stress in the rat.
Topics: Animals; Anxiety; Behavior, Animal; Brain; Chromatography, High Pressure Liquid; Chronic Disease; Co | 2011 |
Heightening of the stress response during the first weeks after a mild traumatic brain injury.
Topics: Adrenocorticotropic Hormone; Animals; Brain Injuries; Corticosterone; Dexamethasone; Disease Models, | 2011 |
[Effects of active ingredients in three kidney-tonifying Chinese herbal drugs on gene expression profile of bone marrow stromal cells from a rat model of corticosterone-induced osteoporosis].
Topics: Animals; Bone Density; Bone Marrow Cells; Cell Differentiation; Corticosterone; Disease Models, Anim | 2011 |
Long-term maternal separation differentially alters serum corticosterone levels and blood neutrophil activity in A/J and C57BL/6 mouse offspring.
Topics: Animals; Chronic Disease; Corticosterone; Disease Models, Animal; Female; Immune Tolerance; Male; Ma | 2011 |
The role of glucocorticoids in the immediate vs. delayed effects of acute ethanol exposure on cytokine production in a binge drinking model.
Topics: Alcoholism; Animals; Cells, Cultured; Corticosterone; Disease Models, Animal; Ethanol; Immunosuppres | 2011 |
Increased anxiety-related behaviour in Hint1 knockout mice.
Topics: Animals; Anxiety; Behavior, Animal; Corticosterone; Dark Adaptation; Disease Models, Animal; Explora | 2011 |
Chronic potassium depletion increases adrenal progesterone production that is necessary for efficient renal retention of potassium.
Topics: Adrenal Glands; Aldosterone; Analysis of Variance; Animals; Cell Line; Chronic Disease; Corticostero | 2011 |
St. John's wort may relieve negative effects of stress on spatial working memory by changing synaptic plasticity.
Topics: Animals; Blotting, Western; Corticosterone; Disease Models, Animal; GAP-43 Protein; Hippocampus; Hyp | 2011 |
The effects of voluntary, involuntary, and forced exercises on brain-derived neurotrophic factor and motor function recovery: a rat brain ischemia model.
Topics: Animals; Brain Ischemia; Brain-Derived Neurotrophic Factor; Corticosterone; Disease Models, Animal; | 2011 |
Effects of maternal L-tryptophan depletion and corticosterone administration on neurobehavioral adjustments in mouse dams and their adolescent and adult daughters.
Topics: Age Factors; Animals; Animals, Newborn; Animals, Outbred Strains; Brain; Brain-Derived Neurotrophic | 2011 |
Enhanced fear expression in a psychopathological mouse model of trait anxiety: pharmacological interventions.
Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Behavior, Animal; Corticosterone; Disease Models, A | 2011 |
Corticotropin-releasing hormone (CRH) transgenic mice display hyperphagia with increased Agouti-related protein mRNA in the hypothalamic arcuate nucleus.
Topics: Adipose Tissue; Agouti-Related Protein; Animals; Arcuate Nucleus of Hypothalamus; Body Weight; Corti | 2011 |
Opposing effects of chronic stress and weight restriction on cardiovascular, neuroendocrine and metabolic function.
Topics: Animals; Blood Glucose; Body Weight; Cardiovascular Physiological Phenomena; Corticosterone; Disease | 2011 |
Stress-induced alterations in anxiety-like behavior and adaptations in plasticity in the bed nucleus of the stria terminalis.
Topics: Adaptation, Physiological; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Biophysics; Cor | 2011 |
Increased hippocampal tau phosphorylation and axonal mitochondrial transport in a mouse model of chronic stress.
Topics: Animals; Anxiety Disorders; Axonal Transport; Cells, Cultured; Chronic Disease; Corticosterone; Cort | 2012 |
Cognitive and locomotor/exploratory behavior after chronic exercise in the olfactory bulbectomy animal model of depression.
Topics: Animals; Body Weight; Cognition; Conditioning, Psychological; Corticosterone; Depression; Disease Mo | 2011 |
Neonatal exposure to constant light prevents anhedonia-like behavior induced by constant light exposure in adulthood.
Topics: Affective Symptoms; Age Factors; Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Behavi | 2011 |
Serotonergic neurotransmission in the ventral hippocampus is enhanced by corticosterone and altered by chronic amphetamine treatment.
Topics: Amphetamines; Animals; Anti-Inflammatory Agents; CA1 Region, Hippocampal; Central Nervous System Sti | 2011 |
Stimulation of the prelimbic cortex differentially modulates neuroendocrine responses to psychogenic and systemic stressors.
Topics: Adrenocorticotropic Hormone; Amygdala; Animals; Bicuculline; Corticosterone; Disease Models, Animal; | 2011 |
Low dietary sodium is anxiogenic in rats.
Topics: Animals; Anxiety; Body Weight; Corticosterone; Depression; Disease Models, Animal; Food Preferences; | 2011 |
Differential effects of social defeat in rats with high and low locomotor response to novelty.
Topics: Analysis of Variance; Animals; Anxiety; Corticosterone; Disease Models, Animal; Exploratory Behavior | 2011 |
Differential responses of corticotropin-releasing factor and urocortin 1 to acute pain stress in the rat brain.
Topics: Analysis of Variance; Animals; Brain; Corticosterone; Corticotropin-Releasing Hormone; Disease Model | 2011 |
Hydration state controls stress responsiveness and social behavior.
Topics: Adrenocorticotropic Hormone; Analysis of Variance; Animals; Behavior, Animal; Blood Pressure; Cortic | 2011 |
Beneficial behavioural and neurogenic effects of agomelatine in a model of depression/anxiety.
Topics: Acetamides; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; Cell Proliferati | 2012 |
Effects of a selective Y2R antagonist, JNJ-31020028, on nicotine abstinence-related social anxiety-like behavior, neuropeptide Y and corticotropin releasing factor mRNA levels in the novelty-seeking phenotype.
Topics: Amygdala; Animals; Anxiety; Benzamides; CA3 Region, Hippocampal; Corticosterone; Corticotropin-Relea | 2011 |
Acute corticosterone increases conditioned spontaneous orofacial behaviors but fails to influence dose related LiCl-induced conditioned "gaping" responses in a rodent model of anticipatory nausea.
Topics: Animals; Anticipation, Psychological; Behavior, Animal; Conditioning, Psychological; Corticosterone; | 2011 |
Effects of comfort food on food intake, anxiety-like behavior and the stress response in rats.
Topics: Animals; Anxiety; Blood Glucose; Corticosterone; Dietary Carbohydrates; Dietary Fats; Disease Models | 2011 |
Effects of chronic stress and corticosterone on sialidase activity in the rat hippocampus.
Topics: Animals; Chronic Disease; Corticosterone; Disease Models, Animal; Hippocampus; Immobilization; Male; | 2011 |
Altered aortic vascular reactivity in the unpredictable chronic mild stress model of depression in mice: UCMS causes relaxation impairment to ACh.
Topics: Acetylcholine; Animals; Aorta; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; | 2011 |
Oxidative damage and HSP70 expression in masseter muscle induced by psychological stress in rats.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Analysis of Variance; Animals; Anxiety; Body Weight; Ca | 2011 |
Dietary arginine depletion reduces depressive-like responses in male, but not female, mice.
Topics: Aggression; Animals; Anxiety; Arginine; Body Weight; Corticosterone; Depression; Disease Models, Ani | 2011 |
Do mice habituate to "gentle handling?" A comparison of resting behavior, corticosterone levels and synaptic function in handled and undisturbed C57BL/6J mice.
Topics: Animals; Corticosterone; Disease Models, Animal; Female; Habituation, Psychophysiologic; Handling, P | 2011 |
Antidepressants recruit new neurons to improve stress response regulation.
Topics: Animals; Antidepressive Agents; Cell Count; Corticosterone; Depression; Dexamethasone; Disease Model | 2011 |
Deficient serotonin neurotransmission and depression-like serotonin biomarker alterations in tryptophan hydroxylase 2 (Tph2) loss-of-function mice.
Topics: Animals; Behavior, Animal; Biomarkers; Corticosterone; Depression; Disease Models, Animal; Extracell | 2012 |
Effects of early life trauma are dependent on genetic predisposition: a rat study.
Topics: Animals; Anxiety; Attention Deficit Disorder with Hyperactivity; Corticosterone; Disease Models, Ani | 2011 |
Do stress responses promote leukemia progression? An animal study suggesting a role for epinephrine and prostaglandin-E2 through reduced NK activity.
Topics: Animals; Cell Line, Tumor; Corticosterone; Dinoprostone; Disease Models, Animal; Disease Progression | 2011 |
Effect of environmental enrichment on the immunoendocrine aging of male and female triple-transgenic 3xTg-AD mice for Alzheimer's disease.
Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cell Proliferation; Chemotaxis; C | 2011 |
The potent anti-inflammatory agent escin does not increase corticosterone secretion and immune cell apoptosis in mice.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Capillary Permeability; Corticosterone; Disease Models | 2011 |
Thymic involution and corticosterone level in Sandhoff disease model mice: new aspects the pathogenesis of GM2 gangliosidosis.
Topics: Age Factors; Animals; Apoptosis; Atrophy; beta-Hexosaminidase alpha Chain; Caspases; Corticosterone; | 2011 |
The interleukin-6 and noradrenaline mediated inflammation-stress feedback mechanism is dysregulated in metabolic syndrome: effect of exercise.
Topics: Adaptation, Physiological; Analysis of Variance; Animals; Blood Glucose; C-Reactive Protein; Chromat | 2011 |
Behavioural and neurochemical evaluation of Perment an herbal formulation in chronic unpredictable mild stress induced depressive model.
Topics: Animals; Behavior, Animal; Chronic Disease; Corticosterone; Depression; Disease Models, Animal; Expl | 2011 |
Chronic psychosocial stress induces reversible mitochondrial damage and corticotropin-releasing factor receptor type-1 upregulation in the rat intestine and IBS-like gut dysfunction.
Topics: Animals; Body Weight; Colon; Corticosterone; Corticotropin-Releasing Hormone; Crowding; Defecation; | 2012 |
Chronic isolation stress predisposes the frontal cortex but not the hippocampus to the potentially detrimental release of cytochrome c from mitochondria and the activation of caspase-3.
Topics: Analysis of Variance; Animals; Apoptosis; Caspase 3; Chronic Disease; Corticosterone; Cytochromes c; | 2011 |
Chronic juvenile stress produces corticolimbic dendritic architectural remodeling and modulates emotional behavior in male and female rats.
Topics: Adaptation, Psychological; Amygdala; Anhedonia; Animals; Chronic Disease; Corticosterone; Dendrites; | 2012 |
Differential effects of maternal immune activation and juvenile stress on anxiety-like behaviour and physiology in adult rats: no evidence for the "double-hit hypothesis".
Topics: Acoustic Stimulation; Adrenal Glands; Analysis of Variance; Animals; Animals, Newborn; Anxiety; Body | 2011 |
Paternal transmission of stress-induced pathologies.
Topics: Animals; Anxiety; Corticosterone; Depression; Disease Models, Animal; Father-Child Relations; Father | 2011 |
Adrenocortical cell transplantation reverses a murine model of adrenal failure.
Topics: Adrenal Cortex; Adrenal Insufficiency; Adrenalectomy; Animals; Cell Transplantation; Corticosterone; | 2011 |
Genetic, pharmacological and lesion analyses reveal a selective role for corticohippocampal GLUN2B in a novel repeated swim stress paradigm.
Topics: Analysis of Variance; Animals; Cerebral Cortex; Corticosterone; Dark Adaptation; Disease Models, Ani | 2011 |
Altered temporal patterns of anxiety in aged and amyloid precursor protein (APP) transgenic mice.
Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Anxiety; Basal Nucleus of Meynert | 2011 |
Stress response and humoral immune system alterations related to chronic hypergravity in mice.
Topics: Animals; Anxiety; Atrophy; Biomarkers; Body Weight; Corticosterone; Cytokines; Disease Models, Anima | 2012 |
Local metabolism of glucocorticoids in Prague hereditary hypertriglyceridemic rats--effect of hypertriglyceridemia and gender.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Carbohydrate Dehydrogenases; Corticosterone; D | 2011 |
Organic cation transporter 2 controls brain norepinephrine and serotonin clearance and antidepressant response.
Topics: Action Potentials; Animals; Antidepressive Agents, Second-Generation; Anxiety; Brain; Corticosterone | 2012 |
Recruitment of prefrontal cortical endocannabinoid signaling by glucocorticoids contributes to termination of the stress response.
Topics: Animals; Arachidonic Acids; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Corticosterone; Dise | 2011 |
Time-dependent effects of starvation on serum, pituitary and hypothalamic leptin levels in rats.
Topics: Animals; Biomarkers; Blood Glucose; Circadian Rhythm; Corticosterone; Disease Models, Animal; Energy | 2011 |
Inhibition of food intake induced by acute stress in rats is due to satiation effects.
Topics: Adrenocorticotropic Hormone; Animals; Blood Glucose; Body Weight; Corticosterone; Disease Models, An | 2011 |
Genetic predisposition to anxiety-related behavior predicts predator odor response.
Topics: Analysis of Variance; Animals; Anxiety; Corticosterone; Disease Models, Animal; Escape Reaction; Maz | 2011 |
Early-life exposure to lipopolysaccharide reduces the severity of experimental autoimmune encephalomyelitis in adulthood and correlated with increased urine corticosterone and apoptotic CD4+ T cells.
Topics: Analysis of Variance; Animals; Animals, Newborn; Annexin A5; Antigens, CD; Apoptosis; CD4-Positive T | 2011 |
Membrane mineralocorticoid but not glucocorticoid receptors of the dorsal hippocampus mediate the rapid effects of corticosterone on memory retrieval.
Topics: Animals; Corticosterone; Disease Models, Animal; Hippocampus; Male; Memory; Memory Disorders; Mice; | 2011 |
[The influence of suoquan capsule on the mRNA expression of CYP11B2 in deficiency of the kidney and diuresis rats].
Topics: Adenine; Aldosterone; Animals; Corticosterone; Cytochrome P-450 CYP11B2; Disease Models, Animal; Diu | 2011 |
Are different biological mechanisms involved in the transmission of maternal versus paternal stress-induced vulnerability to offspring?
Topics: Animals; Anxiety; Corticosterone; Depression; Disease Models, Animal; Father-Child Relations; Father | 2011 |
Magnesium deficiency induces anxiety and HPA axis dysregulation: modulation by therapeutic drug treatment.
Topics: Adrenocorticotropic Hormone; Analysis of Variance; Animals; Anxiety; Corticosterone; Corticotropin-R | 2012 |
The involvement of FK506-binding protein 51 (FKBP5) in the behavioral and neuroendocrine effects of chronic social defeat stress.
Topics: Analysis of Variance; Animals; Corticosterone; Disease Models, Animal; Exploratory Behavior; Gene Ex | 2012 |
[Effect of chronic stress during puberty on the reproductive system of female rats with experimental hyperandrogenicity].
Topics: Androstenedione; Animals; Chronic Disease; Corticosterone; Disease Models, Animal; Estrous Cycle; Fe | 2011 |
The influence of corticosterone on antizyme gene expression in early regenerating rat liver.
Topics: Animals; Corticosterone; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation; Hepa | 2011 |
Induction of multiple reinstatements of ethanol- and sucrose-seeking behavior in Long-Evans rats by the α-2 adrenoreceptor antagonist yohimbine.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Conditioning, Operant; Corticosterone; Disease Mod | 2011 |
Lesions of the ventral ascending noradrenergic bundles decrease the stress response to occlusal disharmony in rats.
Topics: Animals; Corticosterone; Disease Models, Animal; Electrochemistry; Male; Malocclusion; Medulla Oblon | 2011 |
Gestational and postpartum corticosterone exposure to the dam affects behavioral and endocrine outcome of the offspring in a sexually-dimorphic manner.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Cell Proliferation; | 2012 |
Daidzein effects on ACTH cells: immunohistomorphometric and hormonal study in an animal model of the andropause.
Topics: Andropause; Animals; Corticosterone; Corticotrophs; Disease Models, Animal; Estradiol; Estrogens; Im | 2011 |
Disease progression in a mouse model of amyotrophic lateral sclerosis: the influence of chronic stress and corticosterone.
Topics: Amyotrophic Lateral Sclerosis; Animals; Corticosterone; Disease Models, Animal; Disease Progression; | 2011 |
Alterations in anxiety-like behavior following knockout of the uncoupling protein 2 (ucp2) gene in mice.
Topics: Animals; Anxiety; Chromatography, High Pressure Liquid; Corticosterone; Disease Models, Animal; Dopa | 2011 |
Behavioral sexual dimorphism in models of anxiety and depression due to changes in HPA axis activity.
Topics: Adrenalectomy; Analysis of Variance; Animals; Anxiety; Corticosterone; Dark Adaptation; Depression; | 2012 |
How porphyrinogenic drugs modeling acute porphyria impair the hormonal status that regulates glucose metabolism. Their relevance in the onset of this disease.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Disease Models, Animal; Female; Glucose; Porph | 2011 |
A time-dependent history of mood disorders in a murine model of neuropathic pain.
Topics: Adaptation, Ocular; Animals; Behavior, Animal; Corticosterone; Cyclic AMP Response Element-Binding P | 2011 |
Social stress-induced hypothyroidism is attenuated by antidepressant treatment in rats.
Topics: Adipose Tissue, Brown; Analysis of Variance; Animals; Antidepressive Agents; Body Weight; Corticoste | 2012 |
Pharmacological modulation of stress-induced behavioral changes in the light/dark exploration test in male C57BL/6J mice.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Body Weight; Central Nervous System Stimulants; | 2012 |
Chronic non-invasive corticosterone administration abolishes the diurnal pattern of tph2 expression.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Anxiety; Blood Glucose; Circadian Rhythm; Cort | 2012 |
Lateralized amygdala activation: importance in the regulation of anxiety and pain behavior.
Topics: Amygdala; Analysis of Variance; Animals; Anti-Inflammatory Agents; Anxiety; Cholesterol; Colon; Cort | 2012 |
Stress during development alters anxiety-like behavior and hippocampal neurotransmission in male and female rats.
Topics: Age Factors; Animals; Animals, Newborn; Anxiety; Biogenic Monoamines; Chromatography, High Pressure | 2012 |
Depressive phenotypes evoked by experimental diabetes are reversed by insulin.
Topics: Analysis of Variance; Animals; Blood Glucose; Brain; Brain-Derived Neurotrophic Factor; Bromodeoxyur | 2012 |
Type 1 5α-reductase may be required for estrous cycle changes in affective behaviors of female mice.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha-Dihydroprogesterone; Animals; Anxiety; Cerebral Corte | 2012 |
CRF2 receptor-deficiency eliminates opiate withdrawal distress without impairing stress coping.
Topics: Adaptation, Psychological; Animals; Behavior, Addictive; Brain; Corticosterone; Corticotropin-Releas | 2012 |
Green tea polyphenols produce antidepressant-like effects in adult mice.
Topics: Administration, Oral; Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Camellia sinensis | 2012 |
Environmental enrichment compensates for the effects of stress on disease progression in Tg2576 mice, an Alzheimer's disease model.
Topics: Age Factors; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of V | 2011 |
A comparison of activation patterns of cells in selected prefrontal cortical and amygdala areas of rats which are more or less anxious in response to predator exposure or submersion stress.
Topics: Adrenocorticotropic Hormone; Amygdala; Analysis of Variance; Animals; Anxiety; Cats; Corticosterone; | 2012 |
Effects of epinephrine and cortisol on the analgesic activity of metyrosine in rats.
Topics: Adrenergic beta-Antagonists; alpha-Methyltyrosine; Analgesics; Animals; Carrageenan; Chromatography, | 2011 |
Early life stress inhibits expression of a novel innate immune pathway in the developing hippocampus.
Topics: Acute-Phase Proteins; Animals; Animals, Newborn; Anxiety; Behavior, Animal; Carrier Proteins; Cortic | 2012 |
Effects of acute restraint stress on different components of memory as assessed by object-recognition and object-location tasks in mice.
Topics: Analysis of Variance; Animals; Corticosterone; Disease Models, Animal; Male; Memory Disorders; Memor | 2012 |
Exposure to enriched environment restores the mRNA expression of mineralocorticoid and glucocorticoid receptors in the hippocampus and ameliorates depressive-like symptoms in chronically stressed rats.
Topics: Animals; Body Weight; Corticosterone; Depression; Disease Models, Animal; Environment; Exploratory B | 2011 |
Behavioral and neuroendocrine effects of the exposure to chronic restraint or variable stress in early adolescent rats.
Topics: Animals; Behavior, Animal; Chronic Disease; Corticosterone; Disease Models, Animal; Male; Motor Acti | 2012 |
Pharmacological relationship between nicotinic and opioid systems in analgesia and corticosterone elevation.
Topics: Analgesics, Opioid; Animals; Corticosterone; Disease Models, Animal; Drug Administration Schedule; F | 2011 |
Maternal exercise decreases maternal deprivation induced anxiety of pups and correlates to increased prefrontal cortex BDNF and VEGF.
Topics: Animals; Animals, Newborn; Anxiety; Brain-Derived Neurotrophic Factor; Corticosterone; Disease Model | 2011 |
Chronic mild stress accelerates the onset and progression of the Alzheimer's disease phenotype in Tg2576 mice.
Topics: Age Factors; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Chro | 2012 |
Corticotrophin releasing factor accelerates neuropathology and cognitive decline in a mouse model of Alzheimer's disease.
Topics: Age Factors; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of V | 2012 |
Tianeptine reverses stress-induced asymmetrical hippocampal volume and N-acetylaspartate loss in rats: an in vivo study.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Aspartic Acid; Choline; Chromatogra | 2011 |
Sub-chronic dietary tryptophan depletion--an animal model of depression with improved face and good construct validity.
Topics: Aldosterone; Analysis of Variance; Animals; Body Weight; Brain; Calcium-Binding Proteins; Catecholam | 2012 |
Chronic social defeat up-regulates expression of norepinephrine transporter in rat brains.
Topics: Adrenalectomy; Animals; Brain; Corticosterone; Cyclic AMP Response Element-Binding Protein; Cyclic A | 2012 |
Lack of elevations in glucocorticoids correlates with dysphoria-like behavior after repeated social defeat.
Topics: Adrenal Glands; Anhedonia; Animals; Anxiety; CA2 Region, Hippocampal; Corticosterone; Depression; Di | 2012 |
Peony glycosides reverse the effects of corticosterone on behavior and brain BDNF expression in rats.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Brain; Br | 2012 |
Highly pathogenic avian influenza virus H5N1 infection in a long-distance migrant shorebird under migratory and non-migratory states.
Topics: Animal Migration; Animals; Body Weight; Charadriiformes; Corticosterone; Disease Models, Animal; Imm | 2011 |
Cannabinoid CB₁ receptor restrains accentuated activity of hypothalamic corticotropin-releasing factor and brainstem tyrosine hydroxylase neurons in endotoxemia-induced hypophagia in rats.
Topics: Animals; Anorexia Nervosa; Body Weight; Brain Stem; Cell Count; Corticosterone; Corticotropin-Releas | 2012 |
Ascorbic acid treatment, similarly to fluoxetine, reverses depressive-like behavior and brain oxidative damage induced by chronic unpredictable stress.
Topics: Animals; Antidepressive Agents; Antioxidants; Ascorbic Acid; Catalase; Cerebral Cortex; Corticostero | 2012 |
[Gastric mucosal susceptibility for ulcerogenic effect of indometacin at different time points of streptozotocin-induced diabetes development].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Corticosterone; Diabetes Mellitus, | 2011 |
Chronic fluoxetine treatment and maternal adversity differentially alter neurobehavioral outcomes in the rat dam.
Topics: Animals; Antidepressive Agents, Second-Generation; Cell Count; Corticosterone; Disease Models, Anima | 2012 |
A rodent model of rapid-onset diabetes induced by glucocorticoids and high-fat feeding.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipose Tissue; Adiposity; Animals; Body Composition; C | 2012 |
Pharmacological interference with the glucocorticoid system influences symptoms and lifespan in a mouse model of Rett syndrome.
Topics: Animals; Corticosterone; Disease Models, Animal; Female; Gene Expression Regulation; Glucocorticoids | 2012 |
Priming of metabolic dysfunctions by prenatal immune activation in mice: relevance to schizophrenia.
Topics: Acute-Phase Reaction; Animals; Body Composition; Corticosterone; Cytokines; Disease Models, Animal; | 2013 |
Physiological and behavioural responsivity to stress and anxiogenic stimuli in COMT-deficient mice.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Behavior, Animal; Benzophenones; Catechol O-Meth | 2012 |
Beneficial effects of benzodiazepine diazepam on chronic stress-induced impairment of hippocampal structural plasticity and depression-like behavior in mice.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Brain-Derived Neurotrophic Factor; Corticosteron | 2012 |
Mutation of Gtf2ird1 from the Williams-Beuren syndrome critical region results in facial dysplasia, motor dysfunction, and altered vocalisations.
Topics: Analysis of Variance; Animals; Animals, Newborn; Body Temperature; Body Weight; Brain; Circadian Rhy | 2012 |
Diurnal rhythms are altered in a mouse model of multiple sclerosis.
Topics: Animals; Chronobiology Disorders; Circadian Rhythm; CLOCK Proteins; Corticosterone; Disease Models, | 2012 |
Crh and Oprm1 mediate anxiety-related behavior and social approach in a mouse model of MECP2 duplication syndrome.
Topics: Animals; Anxiety; Behavior, Animal; Corticosterone; Corticotropin-Releasing Hormone; Disease Models, | 2012 |
Differential effects of voluntary and forced exercise on stress responses after traumatic brain injury.
Topics: Adrenocorticotropic Hormone; Animals; Brain Injuries; Brain-Derived Neurotrophic Factor; Corticoster | 2012 |
Adrenalectomy stimulates the formation of initial atherosclerotic lesions: reversal by adrenal transplantation.
Topics: Adrenal Glands; Adrenalectomy; Animals; Aortic Diseases; Atherosclerosis; Cholesterol; Corticosteron | 2012 |
Stress and the anti-influenza immune response: repeated social defeat augments clonal expansion of CD8(+)T cells during primary influenza A viral infection.
Topics: Analysis of Variance; Animals; CD8 Antigens; CD8-Positive T-Lymphocytes; Corticosterone; Disease Mod | 2012 |
Corticosterone reduces brain mitochondrial function and expression of mitofusin, BDNF in depression-like rodents regardless of exercise preconditioning.
Topics: Animals; Behavior, Animal; Brain; Brain-Derived Neurotrophic Factor; Corticosterone; Depression; Dis | 2012 |
Psychological stress in adolescent and adult mice increases neuroinflammation and attenuates the response to LPS challenge.
Topics: Aging; Analysis of Variance; Animals; Brain; Corticosterone; Cytokines; Disease Models, Animal; Ence | 2012 |
Paradoxical effects of brain death and associated trauma on rat mesenteric microcirculation: an intravital microscopic study.
Topics: Animals; Brain Death; Corticosterone; Disease Models, Animal; Hemodynamics; Inflammation Mediators; | 2012 |
Disrupted circadian rhythms in a mouse model of schizophrenia.
Topics: Adult; Animals; Arginine Vasopressin; Circadian Rhythm; Corticosterone; Disease Models, Animal; Fema | 2012 |
Neuroendocrine changes and natriuresis in response to social stress in rats.
Topics: Aldosterone; Analysis of Variance; Animals; Behavior, Animal; Catecholamines; Chronic Disease; Corti | 2012 |
Social disruption stress increases IL-6 levels and accelerates atherosclerosis in ApoE-/- mice.
Topics: Animals; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Chemokine CXCL1; Corticosterone; Disea | 2012 |
Testing the cumulative stress and mismatch hypotheses of psychopathology in a rat model of early-life adversity.
Topics: Analysis of Variance; Animals; Animals, Newborn; Apomorphine; Behavior, Animal; Body Weight; Cortico | 2012 |
Chronic cocaine exposure during pregnancy increases postpartum neuroendocrine stress responses.
Topics: Animals; Body Weight; Brain; Cocaine; Corticosterone; Disease Models, Animal; Female; Immobility Res | 2012 |
Moxibustion at mingmen reduces inflammation and decreases IL-6 in a collagen-induced arthritis mouse model.
Topics: Acupuncture Points; Animals; Arthritis, Experimental; Cattle; Collagen Type II; Corticosterone; Dise | 2012 |
Influence of housing conditions from weaning to adulthood on the ventilatory, thermoregulatory, and endocrine responses to hypoxia of adult female rats.
Topics: Age Factors; Aging; Animals; Anxiety, Separation; Behavior, Animal; Body Temperature Regulation; Bod | 2012 |
Predator stress-induced persistent emotional arousal is associated with alterations of plasma corticosterone and hippocampal steroid receptors in rat.
Topics: Analysis of Variance; Animals; Arousal; Cats; Corticosterone; Disease Models, Animal; Hippocampus; M | 2012 |
Social defeat and isolation induce clear signs of a depression-like state, but modest cardiac alterations in wild-type rats.
Topics: Adrenal Glands; Animals; Autonomic Nervous System; Body Temperature; Choice Behavior; Circadian Rhyt | 2012 |
Genetic strain differences in learned fear inhibition associated with variation in neuroendocrine, autonomic, and amygdala dendritic phenotypes.
Topics: Amygdala; Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Anxiety Disorders | 2012 |
Antidepressant-like effects of ginsenoside Rg1 are due to activation of the BDNF signalling pathway and neurogenesis in the hippocampus.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corticosterone; | 2012 |
Plasma corticosterone levels in mouse models of pain.
Topics: Adjuvants, Immunologic; Animals; Capsaicin; Carrageenan; Corticosterone; Disease Models, Animal; Fre | 2012 |
Effects of chronic alcohol consumption and withdrawal on the response of the male and female hypothalamic-pituitary-adrenal axis to acute immune stress.
Topics: Alcohol Drinking; Animals; Corticosterone; Corticotropin-Releasing Hormone; Disease Models, Animal; | 2012 |
[Prenatal stressed female rats develop stable anxious and depressive state in experimental model of post-traumatic stress disorder].
Topics: Animals; Anxiety; Corticosterone; Depression; Disease Models, Animal; Female; Humans; Hydrocortisone | 2011 |
The calm mouse: an animal model of stress reduction.
Topics: Animals; Behavior, Animal; Body Composition; Body Weight; Corticosterone; Disease Models, Animal; En | 2012 |
Chronic mild stress-induced depression-like symptoms in rats and abnormalities in catecholamine uptake in small arteries.
Topics: Analysis of Variance; Anhedonia; Animals; Arteries; Behavior, Animal; Blood Pressure; Catecholamines | 2012 |
Phenotypic effects of repeated psychosocial stress during adolescence in mice mutant for the schizophrenia risk gene neuregulin-1: a putative model of gene × environment interaction.
Topics: Animals; Brain-Derived Neurotrophic Factor; Corticosterone; Cytokines; Disease Models, Animal; Envir | 2012 |
The effect of hypothalamic lesions on hypothalamo-pituitary-adrenal axis activity and inflammation in adjuvant-induced arthritis.
Topics: Animals; Arthritis, Experimental; Biomarkers; Corticosterone; Disease Models, Animal; Freund's Adjuv | 2001 |
Pharmacological suppression of corticosterone secretion in response to a physical stressor does not prevent the delayed persistent increase in circulating basal corticosterone concentration.
Topics: Animals; Biomarkers; Circadian Rhythm; Corticosterone; Disease Models, Animal; Electric Stimulation; | 2001 |
Hormonal and behavioural abnormalities induced by stress in utero: an animal model for depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Circadian Rhythm; Corticosterone; Depression; Dise | 2001 |
Variant brain-derived neurotrophic factor Val66Met polymorphism alters vulnerability to stress and response to antidepressants.
Topics: Adrenocorticotropic Hormone; Analysis of Variance; Animals; Antidepressive Agents; Brain; Brain-Deri | 2012 |
Prostaglandin E2-mediated attenuation of mesocortical dopaminergic pathway is critical for susceptibility to repeated social defeat stress in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Benzazepines; Calcium-Binding Protein | 2012 |
Bupleurum falcatum prevents depression and anxiety-like behaviors in rats exposed to repeated restraint stress.
Topics: Animals; Antidepressive Agents; Anxiety; Brain; Bupleurum; Corticosterone; Depression; Depressive Di | 2012 |
Novel Ocimumoside A and B as anti-stress agents: modulation of brain monoamines and antioxidant systems in chronic unpredictable stress model in rats.
Topics: Animals; Anti-Anxiety Agents; Antioxidants; Biogenic Monoamines; Brain; Cerebrosides; Corticosterone | 2012 |
HDAC6 regulates glucocorticoid receptor signaling in serotonin pathways with critical impact on stress resilience.
Topics: Animals; Behavior, Animal; Brain; Cells, Cultured; Corticosterone; Dexamethasone; Disease Models, An | 2012 |
Inhibition of morphine tolerance is mediated by painful stimuli via central mechanisms.
Topics: Analgesics, Opioid; Animals; Corticosterone; Disease Models, Animal; Dose-Response Relationship, Dru | 2012 |
Exofocal dopaminergic degeneration as antidepressant target in mouse model of poststroke depression.
Topics: Animals; Brain-Derived Neurotrophic Factor; Citalopram; Corticosterone; Depression; Disease Models, | 2012 |
Stress, glucocorticoids and absences in a genetic epilepsy model.
Topics: Animals; Circadian Rhythm; Corticosterone; Disease Models, Animal; Electric Stimulation; Electroence | 2012 |
Binge-like ethanol consumption increases corticosterone levels and neurodegneration whereas occupancy of type II glucocorticoid receptors with mifepristone is neuroprotective.
Topics: Adrenalectomy; Alcohol-Induced Disorders, Nervous System; Alcoholic Intoxication; Analysis of Varian | 2014 |
Diet-induced obesity promotes depressive-like behaviour that is associated with neural adaptations in brain reward circuitry.
Topics: Animals; Anxiety; Behavior, Animal; Corticosterone; Depression; Diet, High-Fat; Disease Models, Anim | 2013 |
Chronic restraint stress attenuates p53 function and promotes tumorigenesis.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cocarcinogenesis; Corticosterone; Disease Models, Animal; Gene | 2012 |
Antinociceptive effects of fluoxetine in a mouse model of anxiety/depression.
Topics: Animals; Antidepressive Agents, Second-Generation; Anxiety; Chronic Pain; Cold Temperature; Corticos | 2012 |
Glucocorticoids protect against the delayed behavioral and cellular effects of acute stress on the amygdala.
Topics: Adrenalectomy; Amygdala; Analysis of Variance; Animals; Anxiety; Corticosterone; Dendritic Spines; D | 2012 |
Deletion of CREB-regulated transcription coactivator 1 induces pathological aggression, depression-related behaviors, and neuroplasticity genes dysregulation in mice.
Topics: Aggression; Animals; Antidepressive Agents, Second-Generation; Arabidopsis Proteins; Biogenic Monoam | 2012 |
Susceptibility to PTSD-like behavior is mediated by corticotropin-releasing factor receptor type 2 levels in the bed nucleus of the stria terminalis.
Topics: Animals; Behavior, Animal; Corticosterone; Disease Models, Animal; Gene Knockdown Techniques; Histon | 2012 |
The protective effects of voluntary exercise against the behavioral consequences of uncontrollable stress persist despite an increase in anxiety following forced cessation of exercise.
Topics: Analysis of Variance; Animals; Body Weight; Corticosterone; Disease Models, Animal; Electroshock; Es | 2012 |
A critical role for protein tyrosine phosphatase nonreceptor type 5 in determining individual susceptibility to develop stress-related cognitive and morphological changes.
Topics: Aggression; Analysis of Variance; Animals; Biophysics; Brain; Calcium Channel Blockers; Cell Line, T | 2012 |
Anxious, hypoactive phenotype combined with motor deficits in Gtf2ird1 null mouse model relevant to Williams syndrome.
Topics: Analysis of Variance; Animals; Anxiety; Basal Ganglia; Body Weight; Circadian Rhythm; Corticosterone | 2012 |
The involvement of noradrenergic mechanisms in the suppressive effects of diazepam on the hypothalamic-pituitary-adrenal axis activity in female rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic Neurons; Adrenocorticotropic Hormone; alpha-Meth | 2012 |
Fear conditioning can contribute to behavioral changes observed in a repeated stress model.
Topics: Adrenergic beta-Antagonists; Analysis of Variance; Animals; Conditioning, Psychological; Corticoster | 2012 |
Female early adult depression results in detrimental impacts on the behavioral performance and brain development in offspring.
Topics: Age Factors; Animals; Animals, Newborn; Astrocytes; Behavior, Animal; Body Weight; Brain; Bromodeoxy | 2012 |
NPY intraperitoneal injections produce antidepressant-like effects and downregulate BDNF in the rat hypothalamus.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Body Weight; Brain-Derived Neurotrophic Factor | 2012 |
Anxiolytic effects of a novel herbal treatment in mice models of anxiety.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Corticosterone; Disease Models, Animal; Male; Maze Learning; | 2012 |
Neonatal exposure to low dose corticosterone persistently modulates hippocampal mineralocorticoid receptor expression and improves locomotor/exploratory behaviour in a mouse model of Rett syndrome.
Topics: Animals; Circadian Rhythm; Corticosterone; Disease Models, Animal; Exploratory Behavior; Hippocampus | 2013 |
Post-exposure sleep deprivation facilitates correctly timed interactions between glucocorticoid and adrenergic systems, which attenuate traumatic stress responses.
Topics: Acoustic Stimulation; Adrenergic Agonists; Analysis of Variance; Animals; Corticosterone; Dendrites; | 2012 |
Different emotional disturbances in two experimental models of temporal lobe epilepsy in rats.
Topics: Animals; Anxiety; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Emotions; Ep | 2012 |
Divergent stress-induced neuroendocrine and behavioral responses prior to puberty.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Age Factors; Aging; Analysis of Variance; Animals; Anim | 2012 |
Uninephrectomy reduces 11β-hydroxysteroid dehydrogenase type 1 and type 2 concomitantly with an increase in blood pressure in rats.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosteron | 2012 |
Task-specific compensation and recovery following focal motor cortex lesion in stressed rats.
Topics: Animals; Corticosterone; Disease Models, Animal; Male; Motor Cortex; Psychomotor Performance; Rats; | 2012 |
Repeatedly stressed rats have enhanced vulnerability to amygdala kindling epileptogenesis.
Topics: Amygdala; Animals; Corticosterone; Disease Models, Animal; Electric Stimulation; Epilepsy; Female; H | 2013 |
Environmental enrichment rescues female-specific hyperactivity of the hypothalamic-pituitary-adrenal axis in a model of Huntington's disease.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Analysis of Variance; Animals; Corticosterone; Dexameth | 2012 |
Chronic exposure to corticosterone enhances the neuroinflammatory and neurotoxic responses to methamphetamine.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Body Weight; Brain; Central Nervous System | 2012 |
Sex comparison on long-lasting behavioral and physiological disturbances induced by single shock experience in rats.
Topics: Animals; Avoidance Learning; Body Temperature; Corticosterone; Cues; Disease Models, Animal; Electro | 2012 |
Effects of CB1 and CRF1 receptor antagonists on binge-like eating in rats with limited access to a sweet fat diet: lack of withdrawal-like responses.
Topics: Animals; Anxiety; Bulimia; Cannabinoid Receptor Antagonists; Corticosterone; Dietary Fats; Dietary S | 2012 |
Anti-inflammatory effect of the endocannabinoid anandamide in experimental periodontitis and stress in the rat.
Topics: Alveolar Bone Loss; Animals; Anti-Inflammatory Agents; Arachidonic Acids; Body Weight; Cannabinoid R | 2012 |
NADPH oxidase mediates depressive behavior induced by chronic stress in mice.
Topics: Acetophenones; Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Antioxidants; Ascorb | 2012 |
Neurobiological sequelae of witnessing stressful events in adult mice.
Topics: Animals; Anxiety; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Fluoxetine; | 2013 |
Medial prefrontal cortex transection enhanced stress-induced activation of sympathoadrenal system in rats.
Topics: Adrenal Glands; Animals; Biomarkers; Corticosterone; Disease Models, Animal; Epinephrine; Hypothalam | 2012 |
Myelophil ameliorates brain oxidative stress in mice subjected to restraint stress.
Topics: Animals; Antioxidants; Brain; Catechol O-Methyltransferase; Corticosterone; Disease Models, Animal; | 2012 |
Citalopram decreases tryptophan 2,3-dioxygenase activity and brain 5-HT turnover in swim stressed rats.
Topics: Amygdala; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Citalopram; Corticost | 2012 |
Corticosterone attenuates conditioned fear responses and potentiates the expression of GABA-A receptor alpha-2 subunits in the brain structures of rats selected for high anxiety.
Topics: Amygdala; Animals; Anxiety; Conditioning, Psychological; Corticosterone; Dentate Gyrus; Disease Mode | 2012 |
Different peripheral neuroendocrine responses to Trypanosoma cruzi infection in mice lacking adaptive immunity.
Topics: Adaptive Immunity; Animals; Chagas Disease; Corticosterone; Cytokines; Disease Models, Animal; Homeo | 2012 |
Physical exercise on the rat ventral prostate: steroid hormone receptors, apoptosis and cell proliferation.
Topics: Animals; Apoptosis; Cell Proliferation; Corticosterone; Dihydrotestosterone; Disease Models, Animal; | 2012 |
Evidence for biological roots in the transgenerational transmission of intimate partner violence.
Topics: Adult; Age Factors; Aggression; Agonistic Behavior; Animals; Anxiety; Body Weight; Child; Child Abus | 2012 |
Depressive-like states heighten the aversion to painful stimuli in a rat model of comorbid chronic pain and depression.
Topics: Animals; Chronic Pain; Corticosterone; Depression; Disease Models, Animal; Extracellular Signal-Regu | 2012 |
Characteristics of glucocorticoid synthesis-related factors in the adrenals of obese Zucker rats (short communication).
Topics: Adrenal Glands; Animals; Cholesterol Side-Chain Cleavage Enzyme; Corticosterone; Cytochrome P-450 CY | 2012 |
Fasting hyperglycemia in the Goto-Kakizaki rat is dependent on corticosterone: a confounding variable in rodent models of type 2 diabetes.
Topics: Animals; Confounding Factors, Epidemiologic; Corticosterone; Diabetes Mellitus, Type 2; Disease Mode | 2012 |
The differential role of NOS inhibitors on stress-induced anxiety and neuroendocrine alterations in the rat.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Brain; Corticosterone; Disease Models, | 2012 |
Bax and B-cell-lymphoma 2 mediate proapoptotic signaling following chronic isolation stress in rat brain.
Topics: Analysis of Variance; Animals; bcl-2-Associated X Protein; Brain; Corticosterone; Cytosol; Disease M | 2012 |
Antiinflammatory treatment ameliorates HPA stress axis dysfunction in a mouse model of stress sensitivity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Astrocytes; Corticosterone; Corticotropin | 2012 |
Post-transcriptional effects and interactions between chronic mild stress and acute sleep deprivation: regulation of translation factor and cytoplasmic polyadenylation element-binding protein phosphorylation.
Topics: Analysis of Variance; Animals; Body Weight; Brain; Corticosterone; Disease Models, Animal; Electroen | 2012 |
Modulation of the nuclear factor-kappa B (NF-κB) signalling pathway by glutamine in peritoneal macrophages of a murine model of protein malnutrition.
Topics: Animals; Animals, Outbred Strains; Cells, Cultured; Corticosterone; Dietary Supplements; Disease Mod | 2013 |
Peripubertal-onset but not adult-onset obesity increases IGF-I and drives development of lean mass, which may lessen the metabolic impairment in adult obesity.
Topics: Adrenocorticotropic Hormone; Aging; Animals; Body Composition; Corticosterone; Diet, High-Fat; Disea | 2012 |
Cafeteria diet-induced obesity plus chronic stress alter serum leptin levels.
Topics: Adipose Tissue; Animals; Body Weight; Corticosterone; Diet; Disease Models, Animal; Energy Intake; L | 2012 |
The effect of unilateral adrenalectomy on transformation of adrenal medullary chromaffin cells in vivo: a potential mechanism of asthma pathogenesis.
Topics: Adrenal Medulla; Adrenalectomy; Animals; Asthma; Bronchoconstriction; Chromaffin Cells; Corticostero | 2012 |
Metabotropic glutamate 2/3 receptor antagonists improve behavioral and prefrontal dopaminergic alterations in the chronic corticosterone-induced depression model in mice.
Topics: Animals; Antidepressive Agents; Corticosterone; Depression; Disease Models, Animal; Dopamine; Excita | 2013 |
Protective effects of nizofenone administration on the cognitive impairments induced by chronic restraint stress in mice.
Topics: Acetylcholinesterase; Animals; Antioxidants; Avoidance Learning; Catecholamines; Cognition Disorders | 2013 |
Inhibition of immobilization stress-induced anorexia, behavioral deficits, and plasma corticosterone secretion by injected leptin in rats.
Topics: Animals; Anorexia; Behavior, Animal; Biomarkers; Body Weight; Corticosterone; Disease Models, Animal | 2013 |
Reversal of chronic stress-induced pain by transcranial direct current stimulation (tDCS) in an animal model.
Topics: Animals; Chronic Pain; Corticosterone; Disease Models, Animal; Hippocampus; Humans; Hyperalgesia; In | 2012 |
[A comparative analysis of corticosterone, cortisol and dexametasone effects on gastric erosion in rats].
Topics: Animals; Blood Glucose; Corticosterone; Dexamethasone; Disease Models, Animal; Hydrocortisone; Indom | 2012 |
Low maternal care exacerbates adult stress susceptibility in the chronic mild stress rat model of depression.
Topics: Animals; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Disease Susceptibilit | 2012 |
Stress-dependent and gender-specific neuroregulatory roles of the apelin receptor in the hypothalamic-pituitary-adrenal axis response to acute stress.
Topics: Adrenocorticotropic Hormone; Animals; Apelin Receptors; Circadian Rhythm; Corticosterone; Crosses, G | 2013 |
Fucoidan prevents depression-like behavior in rats exposed to repeated restraint stress.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain; Brain-Derived Neurotrophic Factor; Corticos | 2013 |
Angiotensin II impairs glucose utilization in obese Zucker rats by increasing HPA activity via an adrenal-dependent mechanism.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Angiotensin II; Animals; Blood Glucose; Corticosterone; | 2013 |
Synaptic plasticity, but not hippocampal neurogenesis, mediated the counteractive effect of wolfberry on depression in rats(1).
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents; Antimetabolites, Antineoplastic; Corticost | 2012 |
Hindlimb suspension does not influence mechanical sensitivity, epidermal thickness, and peripheral nerve density in the glabrous skin of the rat hind paw.
Topics: Animals; Behavior, Animal; Biomarkers; Corticosterone; Disease Models, Animal; Epidermis; Hindlimb; | 2013 |
Delayed effects of brain irradiation--part 1: adrenocortical axis dysfunction and hippocampal damage in an adult rat model.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Cranial Irradiation; Disease Models, Animal; H | 2013 |
Propranolol reduces cognitive deficits, amyloid β levels, tau phosphorylation and insulin resistance in response to chronic corticosterone administration.
Topics: Adrenergic beta-Antagonists; Amyloid beta-Peptides; Animals; Cognition Disorders; Corticosterone; Di | 2013 |
Analgesic effects of the non-nitrogen-containing bisphosphonates etidronate and clodronate, independent of anti-resorptive effects on bone.
Topics: Acetic Acid; Analgesics; Animals; Capsaicin; Clodronic Acid; Corticosterone; Diphosphonates; Disease | 2013 |
A chronic combinatory stress model that activates the HPA axis and avoids habituation in BALB/C mice.
Topics: Adrenal Glands; Animals; Catecholamines; Chromatography, High Pressure Liquid; Chronic Disease; Cort | 2013 |
Altered GABAergic and glutamatergic activity within the rat hippocampus and amygdala in rats subjected to repeated corticosterone administration but not restraint stress.
Topics: Amygdala; Animals; Behavior, Animal; Corticosterone; Depression; Depressive Disorder; Disease Models | 2013 |
Sleep loss and cytokines levels in an experimental model of psoriasis.
Topics: Animals; Body Weight; Corticosterone; Cytokines; Disease Models, Animal; Kallikreins; Male; Mice; Mi | 2012 |
Host stress and immune responses during aerosol challenge of Brown Norway rats with Yersinia pestis.
Topics: Aerosols; Animals; Corticosterone; Disease Models, Animal; Female; Inhalation Exposure; Male; Nasal | 2012 |
Differential effects of environmental enrichment and isolation housing on the hormonal and neurochemical responses to stress in the prefrontal cortex of the adult rat: relationship to working and emotional memories.
Topics: Acetylcholine; Analysis of Variance; Animals; Avoidance Learning; Chromatography, High Pressure Liqu | 2013 |
Swimming exercise ameliorates depression-like behavior in chronically stressed rats: relevant to proinflammatory cytokines and IDO activation.
Topics: Analysis of Variance; Animals; Corticosterone; Cytokines; Depression; Disease Models, Animal; Exerci | 2013 |
Alzheimer's disease related markers, cellular toxicity and behavioral deficits induced six weeks after oligomeric amyloid-β peptide injection in rats.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Behavior, Animal; Body Temperature; Body Weight; | 2013 |
Coenzyme Q10 displays antidepressant-like activity with reduction of hippocampal oxidative/nitrosative DNA damage in chronically stressed rats.
Topics: Animals; Antidepressive Agents; Antioxidants; Behavior, Animal; Corticosterone; Depression; Disease | 2013 |
Impact of psychosocial stress on airway inflammation and its mechanism in a murine model of allergic asthma.
Topics: Animals; Anxiety; Asthma; Bronchial Hyperreactivity; Corticosterone; Cytokines; Disease Models, Anim | 2013 |
A new murine model of stress-induced complex atherosclerotic lesions.
Topics: Animals; Atherosclerosis; Blood Pressure; Cholesterol; Coronary Stenosis; Corticosterone; Disease Mo | 2013 |
Adrenocorticotropic hormone ameliorates acute kidney injury by steroidogenic-dependent and -independent mechanisms.
Topics: Acute Kidney Injury; Adrenocorticotropic Hormone; Albuminuria; Animals; Apoptosis; Cecum; Cell Survi | 2013 |
Behavioral stress fails to accelerate the onset and progression of plaque pathology in the brain of a mouse model of Alzheimer's disease.
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; Behavior, Animal; Brain; Cerebral Cortex; | 2013 |
Relation between corticosterone and fear-related behavior in mice selectively bred for high or low alcohol preference.
Topics: Alcoholism; Analysis of Variance; Animals; Behavior, Animal; Conditioning, Psychological; Corticoste | 2014 |
β-endorphin degradation and the individual reactivity to traumatic stress.
Topics: Aminopeptidases; Amygdala; Animals; beta-Endorphin; Corticosterone; Disease Models, Animal; Electros | 2013 |
Single intranasal neuropeptide Y infusion attenuates development of PTSD-like symptoms to traumatic stress in rats.
Topics: Administration, Intranasal; Adrenocorticotropic Hormone; Animals; Blotting, Western; Corticosterone; | 2013 |
Effects of group housing on stress induced emotional and neuroendocrine alterations.
Topics: Analysis of Variance; Animals; Corticosterone; Disease Models, Animal; Exploratory Behavior; Gene Ex | 2013 |
Protective effect of l-theanine on chronic restraint stress-induced cognitive impairments in mice.
Topics: Analysis of Variance; Animals; Catalase; Cognition Disorders; Corticosterone; Disease Models, Animal | 2013 |
Sexual response in female rats with status epilepticus.
Topics: Analysis of Variance; Animals; Corticosterone; Disease Models, Animal; Female; Gonadal Steroid Hormo | 2013 |
Glucocorticoid involvement in memory formation in a rat model for traumatic memory.
Topics: Animals; Biomarkers; Conditioning, Psychological; Corticosterone; Disease Models, Animal; Electrosho | 2002 |
Prenatal opiate withdrawal activates the chick embryo hypothalamic pituitary-adrenal axis and dilates vitelline blood vessels via serotonin(2) receptors.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Chick Embryo; Corticosterone; Disease Models, Animal; Hypothal | 2002 |
Adrenalitis in the non-obese diabetic mouse.
Topics: Adrenal Gland Diseases; Adrenocorticotropic Hormone; Animals; Autoimmune Diseases; Corticosterone; D | 2002 |
Endogenous glucocorticoids attenuate Shiga toxin-2-induced toxicity in a mouse model of haemolytic uraemic syndrome.
Topics: Adrenal Glands; Animals; Corticosterone; Disease Models, Animal; Drug Administration Schedule; Gluco | 2003 |
Does a reduced 11 beta HSD type 2 activity contribute to sodium retention in the nephrotic syndrome?
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Animals; Anti-Inflammatory Agents; Corticosterone; Disease Mo | 2003 |
Social stress increases blood pressure and cardiovascular pathology in a normotensive rat model.
Topics: Adrenal Glands; Animals; Blood Pressure Determination; Corticosterone; Disease Models, Animal; Epine | 2003 |
Effects of glossopharyngeal nerve transection on central and peripheral cytokines and serum corticosterone induced by localized inflammation.
Topics: Afferent Pathways; Animals; Corticosterone; Cytokines; Disease Models, Animal; Glossopharyngeal Nerv | 2003 |
Reduction of inflammation in rats by diazepam: tolerance development.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Corticosterone; Diazepam; Disease Models, Animal; Do | 2003 |
Behavioural and gene transcription alterations induced by spontaneous cannabinoid withdrawal in mice.
Topics: Animals; Autoradiography; Behavior, Animal; Benzoxazines; Binding, Competitive; Body Temperature; Br | 2003 |
Persistent behavioral and autonomic supersensitivity to stress following prenatal stress exposure in rats.
Topics: Animals; Behavior, Animal; Corticosterone; Disease Models, Animal; Female; Maze Learning; Motor Acti | 2003 |
The relevance of differential response to trauma in an animal model of posttraumatic stress disorder.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Discrimination Learning; Disease Models, Anima | 2003 |
Stress-induced suppression of the immune system after withdrawal from chronic cocaine.
Topics: Adrenalectomy; Animals; Cell Division; Cocaine; Corticosterone; Disease Models, Animal; Dopamine Upt | 2003 |
Topiramate normalizes hippocampal NPY-LI in flinders sensitive line 'depressed' rats and upregulates NPY, galanin, and CRH-LI in the hypothalamus: implications for mood-stabilizing and weight loss-inducing effects.
Topics: Affect; Animals; Anticonvulsants; Corpus Striatum; Corticosterone; Corticotropin-Releasing Hormone; | 2003 |
Exposure to forced swim stress does not alter central production of IL-1.
Topics: Adrenal Glands; Animals; Behavior, Animal; Brain; Brain Chemistry; Corticosterone; Cues; Disease Mod | 2003 |
Implantation of a slow release corticosterone pellet induces long-term alterations in serotonergic neurochemistry in the rat brain.
Topics: Adrenal Glands; Animals; Body Weight; Carrier Proteins; Corticosterone; Depression; Disease Models, | 2003 |
The adrenal cortex in experimental congenital diaphragmatic hernia.
Topics: Adrenal Cortex; Adrenal Glands; Animals; Corticosterone; Disease Models, Animal; DNA; Female; Fetus; | 2003 |
Single eight-hour shift of light-dark cycle increases brain-derived neurotrophic factor protein levels in the rat hippocampus.
Topics: Animals; Body Temperature; Brain Chemistry; Brain Stem; Brain-Derived Neurotrophic Factor; Cerebellu | 2003 |
Behavioral, neurochemical, and electrophysiological characterization of a genetic mouse model of depression.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adaptation, Psychological; Animals; Antidepressive Agents; A | 2003 |
Placental 11beta-hydroxysteroid dehydrogenase in Dahl and spontaneously hypertensive rats.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Actins; Animals; Blood Pressure; Corticosterone; Disease Mode | 2003 |
The algogenic-induced nociceptive flexion test in mice: studies on sensitivity of the test and stress on animals.
Topics: Adenosine Triphosphate; Animals; Behavior, Animal; Bites and Stings; Bradykinin; Corticosterone; Dis | 2003 |
Transplacental transfer and subsequent neonate utilization of herpes simplex virus-specific immunity are resilient to acute maternal stress.
Topics: Animals; Animals, Newborn; Antibodies, Viral; Antibody Specificity; Corticosterone; Disease Models, | 2003 |
Cell proliferation in adult hippocampus is decreased by inescapable stress: reversal by fluoxetine treatment.
Topics: Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Bromodeoxyuridine; Cell Count; | 2003 |
Endocrine changes in a rat model of chronic hypoxia mimicking cyanotic heart disease.
Topics: Adaptation, Physiological; Analysis of Variance; Animals; Animals, Newborn; Chronic Disease; Cortico | 2003 |
The effect of emotional stress on the primary humoral immunity of rats.
Topics: Animals; Antibody Formation; Behavior, Animal; Corticosterone; Disease Models, Animal; Epinephrine; | 2003 |
Attenuated stress responsiveness in an animal model for neurodevelopmental psychopathological disorders.
Topics: Adrenocorticotropic Hormone; Amygdala; Animals; Animals, Newborn; Attention; Behavior, Animal; Catec | 2003 |
Glucocorticoid receptors are downregulated in hepatic T lymphocytes in rats with experimental cholangitis.
Topics: 1-Naphthylisothiocyanate; Animals; Cholangitis, Sclerosing; Chronic Disease; Corticosterone; Dehydro | 2003 |
The maternal endocrine environment in the low-protein model of intra-uterine growth restriction.
Topics: Animals; Blood Glucose; Body Weight; Corticosterone; Diet, Protein-Restricted; Disease Models, Anima | 2003 |
Corticosterone and testosterone levels after chronic stress in an animal model of depression.
Topics: Analysis of Variance; Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Behavior, Animal; | 2003 |
Prenatal stress in rats predicts immobility behavior in the forced swim test. Effects of a chronic treatment with tianeptine.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Corticosterone; D | 2003 |
Different regulation of adenylyl cyclase and rolipram-sensitive phosphodiesterase activity on the frontal cortex and hippocampus in learned helplessness rats.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Corticosterone; Cyclic AMP; Cyclic | 2003 |
Relationship between learning, stress and hippocampal brain-derived neurotrophic factor.
Topics: Animals; Avoidance Learning; Brain-Derived Neurotrophic Factor; Corticosterone; Disease Models, Anim | 2003 |
Nicotine withdrawal induces subsensitivity of hypothalamic-pituitary-adrenal axis to stress in rats: implications for precipitation of depression during smoking cessation.
Topics: Adaptation, Physiological; Adrenal Cortex Function Tests; Animals; Corticosterone; Depression; Dexam | 2004 |
Gestational stress induces post-partum depression-like behaviour and alters maternal care in rats.
Topics: Adrenocorticotropic Hormone; Analysis of Variance; Animals; Corticosterone; Depression, Postpartum; | 2004 |
Evaluation of the effects of chronic mild stressors on hedonic and physiological responses: sex and strain compared.
Topics: Animals; Body Weight; Chronic Disease; Corticosterone; Depressive Disorder; Disease Models, Animal; | 2003 |
Impaired T-cell dependent humoral response and its relationship with T lymphocyte sensitivity to stress hormones in a chronic mild stress model of depression.
Topics: Analysis of Variance; Animals; Antibody Formation; Antigens; Chronic Disease; Corticosterone; Depres | 2004 |
Re: External carotid artery territory ischemia impairs outcome in the endovascular filament model of middle cerebral artery occlusion in rats.
Topics: Animals; Carotid Artery, External; Corticosterone; Dehydration; Disease Models, Animal; Disease Prog | 2004 |
Effect of 1-oxo-5beta, 6beta-epoxy-witha-2-ene-27-ethoxy-olide isolated from the roots of Withania somnifera on stress indices in Wistar rats.
Topics: Animals; Behavior, Animal; Cold Temperature; Corticosterone; Creatine Kinase; Disease Models, Animal | 2003 |
Adrenalectomy further suppresses the NT-3 mRNA response to traumatic brain injury but this effect is not reversed with corticosterone.
Topics: Adrenalectomy; Analysis of Variance; Animals; Autoradiography; Brain Injuries; Corticosterone; Disea | 2004 |
Corticotropin-releasing hormone (CRH) produces analgesia in a thermal injury model independent of its effect on systemic beta-endorphin and corticosterone.
Topics: Analgesia; Animals; beta-Endorphin; Burns; Corticosterone; Corticotropin-Releasing Hormone; Diffusio | 2004 |
Total sleep deprivation decreases immobility in the forced-swim test.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; | 2004 |
Chronic stress augments the long-term and acute effects of methamphetamine.
Topics: Amphetamine-Related Disorders; Animals; Body Weight; Chronic Disease; Corpus Striatum; Corticosteron | 2004 |
Effects of coadministration of cannabinoids and morphine on nociceptive behaviour, brain monoamines and HPA axis activity in a rat model of persistent pain.
Topics: Animals; Behavior, Animal; Biogenic Monoamines; Body Temperature; Brain; Brain Chemistry; Cannabidio | 2004 |
Metabolic and endocrine consequences of social stress in a visible burrow system.
Topics: Aggression; Analysis of Variance; Animals; Body Composition; Corticosterone; Disease Models, Animal; | 2004 |
Effect of restraint stress on the progression of experimental periodontitis in rats.
Topics: Adrenocorticotropic Hormone; Alveolar Bone Loss; Animals; Atrophy; Blood Glucose; Corticosterone; Di | 2004 |
Evidence for alterations in alpha2-adrenergic receptor sensitivity in rats exposed to repeated cocaine administration.
Topics: Adrenergic alpha-Agonists; Animals; Brain; Clonidine; Cocaine; Cocaine-Related Disorders; Corticoste | 2004 |
(-)-nicotine ameliorates corticosterone's potentiation of N-methyl-d-aspartate receptor-mediated cornu ammonis 1 toxicity.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Cell Survival; Corticosterone; Disease | 2004 |
Circulating levels of glucocorticoid hormones in WHHL and NZW rabbits: circadian cycle and response to repeated social encounter.
Topics: Animals; Circadian Rhythm; Corticosterone; Disease Models, Animal; Glucocorticoids; Hydrocortisone; | 2004 |
Chronic glucocorticoid deficiency-induced abnormal aggression, autonomic hypoarousal, and social deficit in rats.
Topics: Adrenalectomy; Aggression; Animals; Anxiety; Arousal; Autonomic Nervous System; Behavior, Animal; Co | 2004 |
Sex differences in behavioral, neurochemical and neuroendocrine effects induced by the forced swim test in rats.
Topics: Analysis of Variance; Animals; Behavior, Animal; Blotting, Northern; Brain Chemistry; Corticosterone | 2004 |
Age- and sex-dependent development of adrenocortical hyperactivity in a transgenic mouse model of Alzheimer's disease.
Topics: Age Factors; Alzheimer Disease; Amyloid; Amyloid beta-Protein Precursor; Animals; Anxiety; Body Weig | 2004 |
Immunization with a nonpathogenic HSV-1 strain prevents clinical and neuroendocrine changes of experimental HSV-1 encephalitis.
Topics: Adrenocorticotropic Hormone; Animals; Behavior, Animal; Brain; Corticosterone; Disease Models, Anima | 2004 |
Colitis up-regulates local glucocorticoid activation and down-regulates inactivation in colonic tissue.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Animals; C | 2004 |
Persistence of Staphylococcus aureus colonization on the skin of NC/Nga mice.
Topics: Animals; Colony Count, Microbial; Corticosterone; Dermatitis, Atopic; Dexamethasone; Disease Models, | 2004 |
Neonatal lesions of the ventral hippocampal formation disrupt neuroendocrine responses to auditory stress in the adult rat.
Topics: Acoustic Stimulation; Adrenocorticotropic Hormone; Age Factors; Animals; Animals, Newborn; Corticost | 2004 |
Delayed effects of chronic variable stress during peripubertal-juvenile period on hippocampal morphology and on cognitive and stress axis functions in rats.
Topics: Age Factors; Animals; Atrophy; Cell Differentiation; Chronic Disease; Corticosterone; Disease Models | 2004 |
Experimental parameters affecting the Morris water maze performance of a mouse model of Down syndrome.
Topics: Age Factors; Animals; Avoidance Learning; Body Temperature; Corticosterone; Disease Models, Animal; | 2004 |
Acute global anoxia during C-section birth affects dopamine-mediated behavioural responses and reactivity to stress.
Topics: Adaptation, Psychological; Age Factors; Analysis of Variance; Animals; Cesarean Section; Corticoster | 2004 |
Suppressed fever and hypersensitivity responses in chicks prenatally exposed to opiates.
Topics: Analysis of Variance; Animals; Basophils; Chick Embryo; Chickens; Corticosterone; Disease Models, An | 2004 |
Chronic restraint stress during early Theiler's virus infection exacerbates the subsequent demyelinating disease in SJL mice.
Topics: Animals; Autoantibodies; Behavior, Animal; Body Weight; Chronic Disease; Corticosterone; Demyelinati | 2004 |
A distinct neurochemical profile in WKY rats at baseline and in response to acute stress: implications for animal models of anxiety and depression.
Topics: Animals; Anxiety; Brain; Chromatography, High Pressure Liquid; Corticosterone; Depression; Disease M | 2004 |
Effect of repeated corticosterone injections and restraint stress on anxiety and depression-like behavior in male rats.
Topics: Aggression; Agonistic Behavior; Animals; Anxiety; Arousal; Corticosterone; Depression; Disease Model | 2005 |
Modeling and predicting stress-induced immunosuppression in mice using blood parameters.
Topics: Animals; Atrazine; B-Lymphocytes; Corticosterone; Disease Models, Animal; Ethanol; Female; Genes, MH | 2005 |
Neuroendocrine responses mediate macrophage function after trauma.
Topics: Animals; Corticosterone; Cyclooxygenase 2; Disease Models, Animal; Female; Femoral Fractures; Macrop | 2004 |
Single and repeated stress-induced modulation of phospholipase C catalytic activity and expression: role in LH behavior.
Topics: Animals; Corticosterone; Disease Models, Animal; Electroshock; Escape Reaction; Frontal Lobe; Helple | 2005 |
Prenatal exposure to a repeated variable stress paradigm elicits behavioral and neuroendocrinological changes in the adult offspring: potential relevance to schizophrenia.
Topics: Age Factors; Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Central Nervous System St | 2005 |
Self-injurious behaviour: a comparison of caffeine and pemoline models in rats.
Topics: Adrenocorticotropic Hormone; Animals; Caffeine; Corticosterone; Disease Models, Animal; Dose-Respons | 2004 |
Distribution and acute stressor-induced activation of corticotrophin-releasing hormone neurones in the central nervous system of Xenopus laevis.
Topics: Acute Disease; Age Factors; Amygdala; Animals; Central Nervous System; Cerebellum; Corticosterone; C | 2004 |
Social isolation stress exacerbates autoimmune disease in MRL/lpr mice.
Topics: Analysis of Variance; Animals; Antibodies, Antinuclear; Autoantibodies; Autoimmune Diseases; Cortico | 2005 |
Benzodiazepine effect of (125)I-iomazenil-benzodiazepine receptor binding and serum corticosterone level in a rat model.
Topics: Animals; Brain; Corticosterone; Diazepam; Disease Models, Animal; Flumazenil; Male; Radionuclide Ima | 2005 |
Long-term behavioural alterations in female rats after a single intense footshock followed by situational reminders.
Topics: Animals; Anxiety; Behavior, Animal; Circadian Rhythm; Corticosterone; Disease Models, Animal; Electr | 2005 |
Ferret odor as a processive stress model in rats: neurochemical, behavioral, and endocrine evidence.
Topics: Adrenocorticotropic Hormone; Animals; Brain; Corticosterone; Disease Models, Animal; Ferrets; Male; | 2005 |
Antianxiety and antidepressive behavior produced by physiological estradiol regimen may be modulated by hypothalamic-pituitary-adrenal axis activity.
Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Corticosterone; Depression; Disease Models | 2005 |
Chronic low-dose corticosterone supplementation enhances acquired epileptogenesis in the rat amygdala kindling model of TLE.
Topics: Amygdala; Animals; Corticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Electri | 2005 |
Altered neuroendocrine response and gastric dysmotility in the Flinders Sensitive Line rat.
Topics: Animals; Buspirone; Corticosterone; Disease Models, Animal; Dyspepsia; Gastrointestinal Motility; Ma | 2005 |
Differential neuroendocrine responses to chronic variable stress in adult Long Evans rats exposed to handling-maternal separation as neonates.
Topics: Adaptation, Physiological; Adrenocorticotropic Hormone; Analysis of Variance; Animals; Animals, Newb | 2005 |
Mechanisms involved in A/J mouse lung tumorigenesis induced by inhalation of an environmental tobacco smoke surrogate.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Animals; Body Weight; Bronchoalveolar Lavage Fluid; Carboxyhemo | 2005 |
Differential effects of periodic maternal separation on adult stress coping in a rat model of extremes in trait anxiety.
Topics: Adaptation, Psychological; Adrenocorticotropic Hormone; Analysis of Variance; Animals; Animals, Newb | 2005 |
Chronic ether stress-induced response of urocortin 1 neurons in the Edinger-Westphal nucleus in the mouse.
Topics: Analysis of Variance; Animals; Autonomic Fibers, Preganglionic; Chronic Disease; Corticosterone; Cor | 2005 |
Reduced activity of 11beta-hydroxysteroid dehydrogenase type 2 is not responsible for sodium retention in nephrotic rats.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Animals; Corticosterone; Dexamethasone; Di | 2005 |
Behavioral, endocrine and immunological characteristics of a murine model of premature aging.
Topics: Age Factors; Aging, Premature; Animals; Anxiety; Behavior, Animal; Corticosterone; Disease Models, A | 2005 |
Behavioral, cognitive and biochemical responses to different environmental conditions in male Ts65Dn mice, a model of Down syndrome.
Topics: Adrenocorticotropic Hormone; Aggression; Analysis of Variance; Animals; Behavior, Animal; Cognition; | 2005 |
Oral testosterone in male rats and the development of experimental autoimmune encephalomyelitis.
Topics: Administration, Oral; Animals; Body Weight; Cell Proliferation; Cholesterol; Corticosterone; Disease | 2005 |
Activity changes and marked stereotypic behavior precede Abeta pathology in TgCRND8 Alzheimer mice.
Topics: Adrenal Medulla; Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Behavior, Animal | 2006 |
Antidepressant action of agomelatine (S 20098) in a transgenic mouse model.
Topics: Acetamides; Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Behavior, Animal; Corticost | 2005 |
Relation between the hypothalamic-pituitary-thyroid (HPT) axis and the hypothalamic-pituitary-adrenal (HPA) axis during repeated stress.
Topics: Adaptation, Physiological; Agouti-Related Protein; Animals; Chronic Disease; Corticosterone; Disease | 2005 |
Morphine withdrawal contributes to Th cell differentiation by biasing cells toward the Th2 lineage.
Topics: Active Transport, Cell Nucleus; Animals; Cell Differentiation; Cell Lineage; Cells, Cultured; Cortic | 2005 |
Two different putative genetic animal models of childhood depression.
Topics: Adrenocorticotropic Hormone; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Cort | 2006 |
Social interaction improves experimental stroke outcome.
Topics: Animals; Behavior, Animal; Brain Ischemia; C-Reactive Protein; Cerebral Infarction; Cohort Studies; | 2005 |
Maternal environment affects endogenous virus induction in the offspring of type 1 diabetes model non-obese diabetic mice.
Topics: Animals; Corticosterone; Diabetes Mellitus, Type 1; Disease Models, Animal; Embryo Transfer; Female; | 2005 |
Cyclic estradiol replacement attenuates stress-induced c-Fos expression in the PVN of ovariectomized rats.
Topics: Animals; Anxiety Disorders; Body Weight; Chronic Disease; Corticosterone; Depression, Postpartum; De | 2005 |
Reduced number of CRF-containing neurons in the central amygdala correlated with enhanced locomotor activity following early postnatal corticosterone treatment in the Wistar rat.
Topics: Amygdala; Analysis of Variance; Animals; Animals, Newborn; Anxiety; Corticosterone; Corticotropin-Re | 2005 |
Stressors affect the response of male and female rats to clomipramine in a model of behavioral despair (forced swim test).
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Clomipramine; Corticosterone; Depressio | 2005 |
Leptin corrects host defense defects after acute starvation in murine pneumococcal pneumonia.
Topics: Acute Disease; Animals; Blood Glucose; Body Weight; Bronchoalveolar Lavage; Corticosterone; Disease | 2006 |
Prepartum chronic ultramild stress increases corticosterone and estradiol levels in gestating mice: implications for postpartum depressive disorders.
Topics: Animals; Corticosterone; Depression, Postpartum; Disease Models, Animal; Estradiol; Female; Hydrocor | 2005 |
Time course of cytokine, corticosterone, and tissue injury responses in mice during heat strain recovery.
Topics: Animals; Body Temperature; Corticosterone; Cytokines; Disease Models, Animal; Heat Stress Disorders; | 2006 |
Endocrine and behavioural plasticity in response to juvenile stress in the semi-precocial rodent Octodon degus.
Topics: Acute Disease; Adaptation, Physiological; Adaptation, Psychological; Age Factors; Animals; Behavior, | 2006 |
Endocrine and immunological correlates of behaviorally identified swim stress resilient and vulnerable rats.
Topics: Adaptation, Psychological; Analysis of Variance; Animals; Body Temperature; Cell Proliferation; Cort | 2006 |
Stimulation of neurogenesis in the hippocampus of the adult rat by fluoxetine requires rhythmic change in corticosterone.
Topics: Age Factors; Aging; Animals; Cell Proliferation; Corticosterone; Dentate Gyrus; Depressive Disorder, | 2006 |
BSB: a new mouse model of multigenic obesity.
Topics: Animals; Body Weight; Corticosterone; Cortisone; Crosses, Genetic; Disease Models, Animal; Female; G | 1993 |
Effect of different doses of corticosterone on depression-like behavior and HPA axis responses to a novel stressor.
Topics: Animals; Behavior, Animal; Body Weight; Corticosterone; Depression; Disease Models, Animal; Dose-Res | 2006 |
Behavioral, central monoaminergic and hypothalamo-pituitary-adrenal axis correlates of fear-conditioned analgesia in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analgesia; Animals; Behavior, Animal; Biogenic Monoamines; Brain; Co | 2006 |
Corticosterone-induced inhibition of gliogenesis in rat hippocampus is counteracted by electroconvulsive seizures.
Topics: Animals; Antigens; Cell Count; Cell Differentiation; Cell Proliferation; Corticosterone; Depression; | 2006 |
Inflammation-susceptible Lewis rats show less sensitivity than resistant Fischer rats in the formalin inflammatory pain test and with repeated thermal testing.
Topics: Analysis of Variance; Animals; Animals, Newborn; Area Under Curve; Behavior, Animal; Corticosterone; | 2006 |
Stress during gestation alters postpartum maternal care and the development of the offspring in a rodent model.
Topics: Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Corticosterone; Disease Models, A | 2006 |
Chronic stress accelerates learning and memory impairments and increases amyloid deposition in APPV717I-CT100 transgenic mice, an Alzheimer's disease model.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cerebral Cortex; Chronic Disease; Cortic | 2006 |
Therapeutic action of cannabinoid on axonal injury induced by peroxynitrite.
Topics: Adrenalectomy; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Axons; Brain Diseases; | 2006 |
Spatial memory deficits in middle-aged mice correlate with lower exploratory activity and a subordinate status: role of hippocampal neurotrophins.
Topics: Age Factors; Aggression; Analysis of Variance; Animals; Behavior, Animal; Choice Behavior; Corticost | 2006 |
Feeding and neuroendocrine responses after recurrent insulin-induced hypoglycemia.
Topics: Adaptation, Physiological; Adrenocorticotropic Hormone; Analysis of Variance; Animals; Blood Glucose | 2006 |
Blood corticosterone concentration reaches critical illness levels early during acute malnutrition in the weanling mouse.
Topics: Acute Disease; Animals; Body Weight; Child Nutrition Disorders; Child, Preschool; Corticosterone; Di | 2006 |
Rosiglitazone attenuates learning and memory deficits in Tg2576 Alzheimer mice.
Topics: Age Factors; Alzheimer Disease; Amyloid beta-Peptides; Analysis of Variance; Animals; Behavior, Anim | 2006 |
Predictors and markers of resistance to neurotropic nematode infection in rodent host.
Topics: Animals; Biomarkers; Brain; Canidae; Corticosterone; Disease Models, Animal; Eosinophils; Immunity, | 2006 |
Antidepressant-like effect of saponins extracted from Chaihu-jia-longgu-muli-tang and its possible mechanism.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Calcium; Cell Survival; Corticosterone; Depression | 2006 |
Enhanced endocrine response to novel environment stress and lack of corticosterone circadian rhythm in staggerer (Rora sg/sg) mutant mice.
Topics: Animals; Chronobiology Disorders; Circadian Rhythm; Corticosterone; Disease Models, Animal; Female; | 2006 |
Somatic pain sensitivity during formation and healing of acetic acid-induced gastric ulcers in conscious rats.
Topics: Acetic Acid; Adrenal Glands; Animals; Anti-Inflammatory Agents, Non-Steroidal; Consciousness; Cortic | 2006 |
Progressive alterations in the hypothalamic-pituitary-adrenal axis in the R6/2 transgenic mouse model of Huntington's disease.
Topics: Adrenocorticotropic Hormone; Adult; Animals; Body Fat Distribution; Bone Density; Corticosterone; Di | 2006 |
Corticosterone response to acute stress in a mouse model of Fragile X syndrome.
Topics: Adaptation, Physiological; Analysis of Variance; Animals; Corticosterone; Disease Models, Animal; Fe | 2006 |
I.c.v. administration of the nonsteroidal glucocorticoid receptor antagonist, CP-472555, prevents exacerbated hypoglycemia during repeated insulin administration.
Topics: Animals; Autonomic Nervous System; Corticosterone; Disease Models, Animal; Dose-Response Relationshi | 2006 |
Androgenic-anabolic steroids associated with mechanical loading inhibit matrix metallopeptidase activity and affect the remodeling of the achilles tendon in rats.
Topics: Achilles Tendon; Anabolic Agents; Analysis of Variance; Androgens; Animals; Biomarkers; Corticostero | 2006 |
Elevation of glucocorticoids is necessary but not sufficient for the escalation of cocaine self-administration by chronic electric footshock stress in rats.
Topics: Animals; Behavior, Addictive; Behavior, Animal; Chronic Disease; Cocaine; Cocaine-Related Disorders; | 2007 |
A novel role for IL-18 in corticosterone-mediated intestinal damage in a two-hit rodent model of alcohol intoxication and injury.
Topics: Alcoholic Intoxication; Animals; Burns; Caspase 1; Caspase Inhibitors; Chemokine CXCL1; Chemokines, | 2006 |
Urocortin 2-deficient mice exhibit gender-specific alterations in circadian hypothalamus-pituitary-adrenal axis and depressive-like behavior.
Topics: Adrenocorticotropic Hormone; Animals; Behavior, Animal; Brain; Cells, Cultured; Chimera; Circadian R | 2006 |
Anxiogenic-like effect of chronic corticosterone in the light-dark emergence task in mice.
Topics: Adrenocortical Hyperfunction; Animals; Anti-Inflammatory Agents; Anxiety; Behavior, Animal; Corticos | 2006 |
High post-partum levels of corticosterone given to dams influence postnatal hippocampal cell proliferation and behavior of offspring: A model of post-partum stress and possible depression.
Topics: Age Factors; Animals; Anxiety; Cell Proliferation; Child; Child of Impaired Parents; Corticosterone; | 2006 |
PACAP 38 as a modulator of immune and endocrine responses during LPS-induced acute inflammation in rats.
Topics: Acute Disease; Animals; Cells, Cultured; Corticosterone; Disease Models, Animal; Drug Interactions; | 2006 |
Behavioral and hypothalamic-pituitary-adrenal responses to anterodorsal thalami nuclei lesions and variable chronic stress in maternally separated rats.
Topics: Adrenocorticotropic Hormone; Animals; Anterior Thalamic Nuclei; Behavior, Animal; Chronic Disease; C | 2006 |
Adaptive acetylcholinesterase splicing patterns attenuate 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in mice.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Behavior, Animal; Brain; Cell Count; Cholinesterase In | 2006 |
Schnurri-2 mutant mice are hypersensitive to stress and hyperactive.
Topics: Animals; Anxiety Disorders; Bone Morphogenetic Proteins; Brain; Corticosterone; Disease Models, Anim | 2006 |
The role of tumor necrosis factor-alpha in stress-induced worsening of cerebral ischemia in rats.
Topics: ADAM Proteins; ADAM17 Protein; Animals; Antibodies; Behavior, Animal; Blotting, Western; Brain Infar | 2006 |
Increased anxiety-like behavior during the post-stress period in mice exposed to repeated restraint stress.
Topics: Analysis of Variance; Animals; Anxiety; Body Weight; Corticosterone; Disease Models, Animal; Explora | 2006 |
Maternal factors and monoamine changes in stress-resilient and susceptible mice: cross-fostering effects.
Topics: Animals; Biogenic Monoamines; Brain; Brain Chemistry; Corticosterone; Disease Models, Animal; Dopami | 2006 |
Anxiety and panic responses to a predator in male and female Ts65Dn mice, a model for Down syndrome.
Topics: Adrenocorticotropic Hormone; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Corticosteron | 2006 |
St john's wort (Hypericum perforatum) counteracts deleterious effects of the chronic restraint stress on recall in rats.
Topics: Animals; Anti-Inflammatory Agents; Avoidance Learning; Chronic Disease; Conditioning, Psychological; | 2006 |
Adiponectin is regulated differently by chronic exercise than by weight-matched food restriction in hyperphagic and obese OLETF rats.
Topics: Adipocytes; Adiponectin; Adipose Tissue; Animals; Corticosterone; Disease Models, Animal; Epididymis | 2006 |
Attenuating corticosterone levels on the day of memory assessment prevents chronic stress-induced impairments in spatial memory.
Topics: Aging; Animals; Chronic Disease; Corticosterone; Disease Models, Animal; Dose-Response Relationship, | 2006 |
Chronobiological disturbances with hyperthermia and hypercortisolism induced by chronic mild stress in rats.
Topics: Analysis of Variance; Animals; Body Temperature; Chronobiology Disorders; Circadian Rhythm; Corticos | 2006 |
Transgenic mice overexpressing glycogen synthase kinase 3beta: a putative model of hyperactivity and mania.
Topics: Adrenocorticotropic Hormone; Animals; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Corticost | 2006 |
Glucocorticoids increase amyloid-beta and tau pathology in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein | 2006 |
Social experience influences hypothalamic oxytocin in the WHHL rabbit.
Topics: Analysis of Variance; Animals; Animals, Inbred Strains; Arteriosclerosis; Corticosterone; Disease Mo | 2006 |
Effect of growth hormone in an experimental model of protein hypercatabolism induced by glucocorticoids.
Topics: Adrenocorticotropic Hormone; Animals; Body Weight; Corticosterone; Dexamethasone; Disease Models, An | 2006 |
Chronic restraint or variable stresses differently affect the behavior, corticosterone secretion and body weight in rats.
Topics: Adaptation, Physiological; Adrenal Glands; Analysis of Variance; Animals; Body Weight; Chronic Disea | 2007 |
The role of corticosterone in prehatch-induced memory deficits in chicks.
Topics: Analysis of Variance; Animals; Avoidance Learning; Chick Embryo; Chickens; Corticosterone; Discrimin | 2006 |
Reduced ingestion of sweetened milk induced by interleukin-1 and lipopolysaccharide is associated with induction of cyclooxygenase-2 in brain endothelia.
Topics: Animals; Appetite Regulation; Body Temperature; Brain; Cerebral Arteries; Corticosterone; Cyclooxyge | 2006 |
Physical training attenuates the stress-induced changes in rat T-lymphocyte function.
Topics: Animals; Apoptosis; Cell Proliferation; Corticosterone; Disease Models, Animal; Hypothalamo-Hypophys | 2006 |
Repeated stress alters the ability of nicotine to activate the hypothalamic-pituitary-adrenal axis.
Topics: Adrenocorticotropic Hormone; Animals; beta-Endorphin; Chronic Disease; Corticosterone; Disease Model | 2006 |
Aggressive behavior and HPA axis hormones after social isolation in adult rats of two different genetic animal models for depression.
Topics: Adaptation, Physiological; Adaptation, Psychological; Adrenocorticotropic Hormone; Aggression; Anima | 2006 |
Amelioration of operation-induced suppression of marginating pulmonary NK activity using poly IC: a potential approach to reduce postoperative metastasis.
Topics: Adenocarcinoma; Animals; Cell Line, Tumor; Corticosterone; Dinoprostone; Disease Models, Animal; Fem | 2007 |
Enhanced anxiety and stress-induced corticosterone release are associated with increased Crh expression in a mouse model of Rett syndrome.
Topics: Animals; Anxiety; Behavior, Animal; Corticosterone; Corticotropin-Releasing Hormone; Disease Models, | 2006 |
Modeling the anxiety-depression continuum hypothesis in domestic fowl chicks.
Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety; Chickens; | 2006 |
Effects of pravastatin in murine collagen-induced arthritis.
Topics: Animals; Arthritis, Experimental; Aspartate Aminotransferases; Blood Urea Nitrogen; Chemokine CCL2; | 2007 |
Riboflavin-deficient and Trichinella spiralis-induced stresses on plasma corticosterone associated with spermatogenesis in male Wistar rats.
Topics: Animal Nutritional Physiological Phenomena; Animals; Corticosterone; Disease Models, Animal; Male; R | 2006 |
Human adenovirus 36 induces adiposity, increases insulin sensitivity, and alters hypothalamic monoamines in rats.
Topics: Adenovirus Infections, Human; Adenoviruses, Human; Adipose Tissue; Animals; CCAAT-Enhancer-Binding P | 2006 |
Insulin resistance and low sympathetic nerve activity in the Tsumura Suzuki obese diabetic mouse: a new model of spontaneous type 2 diabetes mellitus and obesity.
Topics: Adiponectin; Adipose Tissue, Brown; Adrenal Glands; Animals; Corticosterone; Diabetes Mellitus, Type | 2006 |
Behavioral evaluation of mice deficient in GABA(B(1)) receptor isoforms in tests of unconditioned anxiety.
Topics: Adrenocorticotropic Hormone; Animals; Anxiety; Behavior, Animal; Corticosterone; Disease Models, Ani | 2007 |
Buprenorphine ameliorates the effect of surgery on hypothalamus-pituitary-adrenal axis, natural killer cell activity and metastatic colonization in rats in comparison with morphine or fentanyl treatment.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Breast Neoplasms; Buprenorphine; Corticosterone; | 2007 |
Disruption of the CRF/CRF1 receptor stress system exacerbates the somatic signs of opiate withdrawal.
Topics: Analysis of Variance; Animals; Behavior, Animal; Corticosterone; Corticotropin-Releasing Hormone; Di | 2007 |
Delayed but not early glucocorticoid treatment protects the host during experimental herpes simplex virus encephalitis in mice.
Topics: Animals; Corticosterone; Dexamethasone; Disease Models, Animal; Drug Administration Schedule; Enceph | 2007 |
Neural, endocrine and electroencephalographic hyperreactivity to human contact: a diathesis-stress model of seizure susceptibility in El mice.
Topics: Animals; Cell Count; Corticosterone; Corticotropin-Releasing Hormone; Disease Models, Animal; Diseas | 2007 |
Sex steroid regulation of macrophage migration inhibitory factor in normal and inflamed colon in the female rat.
Topics: Animals; Antibodies, Monoclonal; Colitis; Colon; Corticosterone; Dextran Sulfate; Disease Models, An | 2007 |
Long lasting sex-specific effects upon behavior and S100b levels after maternal separation and exposure to a model of post-traumatic stress disorder in rats.
Topics: Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Conditioning, Psychological; Cort | 2007 |
Prenatal stress increases HPA axis activity and impairs maternal care in lactating female offspring: implications for postpartum mood disorder.
Topics: Adrenocorticotropic Hormone; Animals; Anxiety; Arginine Vasopressin; Corticosterone; Corticotropin-R | 2007 |
Involvement of IL-1beta in acute stress-induced worsening of cerebral ischaemia in rats.
Topics: Animals; Antibodies; Behavior, Animal; Brain Infarction; Brain Ischemia; Corticosterone; Disease Mod | 2007 |
Exercise intensity influences the temporal profile of growth factors involved in neuronal plasticity following focal ischemia.
Topics: Analysis of Variance; Animals; Corticosterone; Disease Models, Animal; Heart Rate; Hippocampus; Inte | 2007 |
Chronic food restriction in young rats results in depression- and anxiety-like behaviors with decreased expression of serotonin reuptake transporter.
Topics: Animals; Animals, Newborn; Anxiety; Behavior, Animal; Brain Chemistry; Corticosterone; Depression; D | 2007 |
Persistent neuroendocrine and behavioral effects of a novel, etiologically relevant mouse paradigm for chronic social stress during adolescence.
Topics: Adaptation, Physiological; Adaptation, Psychological; Adrenal Glands; Adrenocorticotropic Hormone; A | 2007 |
The role of vasopressin in chronic stress studied in a chronic mild stress model of depression.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Body Weight; Chronic Disease; Corticosterone; | 2007 |
Coerulear activation by crh and its role in hypertension induced by prenatal malnutrition in the rat.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Corticosterone; Corticotropin-Releasi | 2007 |
Hypothalamus-pituitary-adrenal modifications consequent to chronic stress exposure in an experimental model of depression in rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Corticosterone; Corticotropin-Releasing | 2007 |
Effects of acute and repeated exposure to lipopolysaccharide on cytokine and corticosterone production during remyelination.
Topics: Acute Disease; Animals; Body Weight; CD11b Antigen; Chelating Agents; Chronic Disease; Corpus Callos | 2007 |
Plasma corticosterone, dexamethasone (DEX) suppression and DEX/CRH tests in a rat model of genetic vulnerability to depression.
Topics: Analysis of Variance; Animals; Area Under Curve; Circadian Rhythm; Corticosterone; Corticotropin-Rel | 2007 |
Surgical adrenalectomy with diurnal corticosterone replacement slows escalation and prevents the augmentation of cocaine-induced reinstatement in rats self-administering cocaine under long-access conditions.
Topics: Adrenalectomy; Analysis of Variance; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; | 2008 |
Chronic nicotine self-administration augments hypothalamic-pituitary-adrenal responses to mild acute stress.
Topics: Acute Disease; Adrenocorticotropic Hormone; Analysis of Variance; Animals; Corticosterone; Disease M | 2008 |
Liver glucocorticoid receptor and heat shock protein 70 levels in rats exposed to different stress models.
Topics: Adaptation, Physiological; Analysis of Variance; Animals; Chronic Disease; Cold Temperature; Cortico | 2008 |
Pre-training administration of tianeptine, but not propranolol, protects hippocampus-dependent memory from being impaired by predator stress.
Topics: Adrenergic beta-Antagonists; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Corticoste | 2008 |
Effects of acute stress on the day of proestrus on sexual behavior and ovulation in female rats: participation of the angiotensinergic system.
Topics: Acute Disease; Analysis of Variance; Angiotensin II; Animals; Circadian Rhythm; Corticosterone; Dise | 2007 |
Vagus nerve integrity and experimental colitis.
Topics: Animals; C-Reactive Protein; Colitis; Colon; Corticosterone; Dextran Sulfate; Dinitrofluorobenzene; | 2007 |
Chronic unpredictable stress decreases cell proliferation in the cerebral cortex of the adult rat.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Bromodeox | 2007 |
A new model of neonatal stress which produces lasting neurobehavioral effects in adult rats.
Topics: Analgesics, Opioid; Animals; Animals, Newborn; Behavior, Animal; Blood Pressure; Cognition Disorders | 2007 |
The immediate early gene Arc is associated with behavioral resilience to stress exposure in an animal model of posttraumatic stress disorder.
Topics: Adaptation, Physiological; Analysis of Variance; Animals; Behavior, Animal; Cats; Corticosterone; Cy | 2008 |
Glucocorticoid receptor activation is involved in producing abnormal phenotypes of single-prolonged stress rats: a putative post-traumatic stress disorder model.
Topics: Amygdala; Animals; Anxiety Disorders; Avoidance Learning; Cell Death; Corticosterone; Disease Models | 2007 |
Post-traumatic stress behavioural responses in inbred mouse strains: can genetic predisposition explain phenotypic vulnerability?
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Cluster Analysis; Co | 2008 |
Phenotypic analysis of vertigo 2 Jackson mice with a Kcnq1 potassium channel mutation.
Topics: Achlorhydria; Animals; Corticosterone; Disease Models, Animal; Electrocardiography; Female; Gastric | 2007 |
Antidepressant drugs reverse the loss of adult neural stem cells following chronic stress.
Topics: Animals; Antidepressive Agents; Biological Assay; Cell Death; Cells, Cultured; Chronic Disease; Cort | 2007 |
Thymocytes, pre-B cells, and organ changes in a mouse model of chronic ethanol ingestion--absence of subset-specific glucocorticoid-induced immune cell loss.
Topics: Alcoholism; Animals; B-Lymphocyte Subsets; Bone Marrow; Central Nervous System Depressants; Corticos | 2007 |
Rat model of chronic recurrent airway obstructions to study the sleep apnea syndrome.
Topics: Airway Obstruction; Animals; Chronic Disease; Corticosterone; Disease Models, Animal; Enzyme-Linked | 2007 |
Possible involvement of integrin signaling pathway in the process of recovery from restraint stress in rats.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Disease Models, Animal; Gene Expression Regula | 2007 |
The absence of circadian cues during recovery from sepsis modifies pituitary-adrenocortical function and impairs survival.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Circadian Rhythm; Corticosterone; Disease Mode | 2008 |
Corticosterone mediates electroacupuncture-produced anti-edema in a rat model of inflammation.
Topics: Adrenal Glands; Adrenalectomy; Animals; Corticosterone; Disease Models, Animal; Edema; Electroacupun | 2007 |
Anxiogenic-like behavioral phenotype of mice deficient in phosphodiesterase 4B (PDE4B).
Topics: Analysis of Variance; Animals; Anxiety; Avoidance Learning; Behavior, Animal; Brain; Bromodeoxyuridi | 2008 |
Opposite effects of glucocorticoid receptor activation on hippocampal CA1 dendritic complexity in chronically stressed and handled animals.
Topics: Animals; Behavior, Animal; Corticosterone; Dendrites; Disease Models, Animal; Handling, Psychologica | 2008 |
Effect of sleep deprivation on the corticosterone secretion in an experimental model of autoimmune disease.
Topics: Animals; Corticosterone; Disease Models, Animal; Female; Hypothalamo-Hypophyseal System; Lupus Eryth | 2007 |
Enhanced cognitive activity--over and above social or physical activity--is required to protect Alzheimer's mice against cognitive impairment, reduce Abeta deposition, and increase synaptic immunoreactivity.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Analysis of Variance; Animals; Brain; Cognition; Cognition | 2007 |
Effects of chronic and acute stressors and CRF on depression-like behavior in mice.
Topics: Acute Disease; Adaptation, Psychological; Adrenocorticotropic Hormone; Analysis of Variance; Animals | 2008 |
Protective effect of (+)-catechin against gastric mucosal injury induced by ischaemia-reperfusion in rats.
Topics: Administration, Oral; Alkaline Phosphatase; Animals; Antioxidants; Catalase; Catechin; Corticosteron | 2007 |
Altered memory capacities and response to stress in p300/CBP-associated factor (PCAF) histone acetylase knockout mice.
Topics: Age Factors; Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Conditioning, Psyc | 2008 |
Constituents of Ocimum sanctum with antistress activity.
Topics: Animals; Blood Glucose; Cerebrosides; Corticosterone; Coumarins; Creatine Kinase; Disease Models, An | 2007 |
Nicotine-induced prenatal overexposure to maternal glucocorticoid and intrauterine growth retardation in rat.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adrenal Glands; Animals; Cholesterol Side-Chain Cleavag | 2007 |
Gender-related qualitative differences in baseline and post-stress anxiety responses are not reflected in the incidence of criterion-based PTSD-like behaviour patterns.
Topics: Animals; Anxiety Disorders; Behavior, Animal; Corticosterone; Depressive Disorder, Major; Disease Mo | 2009 |
Regionally specific regulation of ERK MAP kinase in a model of antidepressant-sensitive chronic depression.
Topics: Amitriptyline; Animals; Anti-Inflammatory Agents; Antidepressive Agents, Tricyclic; Chronic Disease; | 2008 |
Repeated social defeat-induced depression-like behavioral and biological alterations in rats: involvement of cholecystokinin.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Bromodeoxyuridine; Cell Proliferati | 2008 |
Vmat2 heterozygous mutant mice display a depressive-like phenotype.
Topics: Animals; Antidepressive Agents; Anxiety; Corticosterone; Depressive Disorder, Major; Disease Models, | 2007 |
Strain differences in anxiety-like behavior: association with corticotropin-releasing factor.
Topics: Amygdala; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Corticosterone; Corticotropin-Re | 2008 |
Repeated immobilization stress in the early postnatal period increases stress response in adult rats.
Topics: Adaptation, Physiological; Age Factors; Animals; Body Composition; Body Weight; Chronic Disease; Cor | 2008 |
Hydrogen sulphide-induced hypothermia attenuates stress-related ulceration in rats.
Topics: Adrenocorticotropic Hormone; Animals; Body Temperature; Caspase 12; Corticosterone; Disease Models, | 2008 |
Gene expression of mineralocorticoid and glucocorticoid receptors in the limbic system is related to type-2 like diabetes in leptin-resistant rats.
Topics: Analysis of Variance; Animals; Area Under Curve; Blood Glucose; Body Weight; Corticosterone; Cortico | 2007 |
Effects of chronic social stress in adolescence on anxiety and neuroendocrine response to mild stress in male and female rats.
Topics: Age Factors; Analysis of Variance; Animals; Anxiety; Chronic Disease; Corticosterone; Disease Models | 2008 |
Evaluation of the anxiolytic effects of chrysin, a Passiflora incarnata extract, in the laboratory rat.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Catecholamines; Corti | 2007 |
Antidepressant-like behavioral effects of impaired cannabinoid receptor type 1 signaling coincide with exaggerated corticosterone secretion in mice.
Topics: Adaptation, Psychological; Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Corticos | 2008 |
Protective effect of Triphala on cold stress-induced behavioral and biochemical abnormalities in rats.
Topics: Animals; Behavior, Animal; Cold Temperature; Corticosterone; Disease Models, Animal; Lipid Peroxidat | 2007 |
An anti-immobility effect of exogenous corticosterone in mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; Desipramine; Disease M | 2008 |
Intermittent hypoxia reverses the diurnal glucose rhythm and causes pancreatic beta-cell replication in mice.
Topics: Animals; Blood Glucose; Blood Pressure; Cell Proliferation; Circadian Rhythm; Corticosterone; Diabet | 2008 |
Interleukin-1 receptor type 1-deficient mice fail to develop social stress-associated glucocorticoid resistance in the spleen.
Topics: Adrenal Glands; Animals; CD11b Antigen; Chronic Disease; Corticosterone; Disease Models, Animal; Dom | 2008 |
Adrenocortical changes and arterial hypertension in lipoatrophic A-ZIP/F-1 mice.
Topics: Adipokines; Adipose Tissue, White; Adrenal Cortex; Aldosterone; Animals; Blood Glucose; Blood Pressu | 2008 |
Study of changes in some pathophysiological stress markers in different age groups of an animal model of acute and chronic heat stress.
Topics: Acute Disease; Animals; Blood-Brain Barrier; Body Temperature; Body Weight; Chronic Disease; Cortico | 2007 |
Diurnal behavioral and endocrine effects of chronic shaker stress in mice.
Topics: Analysis of Variance; Animals; Chronic Disease; Circadian Rhythm; Corticosterone; Disease Models, An | 2007 |
Periadolescent stress exposure exerts long-term effects on adult stress responding and expression of prefrontal dopamine receptors in male and female rats.
Topics: Adaptation, Psychological; Age Factors; Analysis of Variance; Animals; Association Learning; Chronic | 2008 |
Stress/aggressiveness-induced immune changes are altered in adult rats submitted to neonatal malnutrition.
Topics: Aggression; Aging; Animals; Antibodies; Antibody Formation; Behavior, Animal; Corticosterone; Diseas | 2007 |
Antidepressant-like effects of the mixture of honokiol and magnolol from the barks of Magnolia officinalis in stressed rodents.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Biphenyl Compounds; Corticosterone; Disease Models | 2008 |
Glucocorticoid availability in colonic inflammation of rat.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Animals; B | 2008 |
Long-term behavioral and neuroendocrine alterations following chronic social stress in mice: implications for stress-related disorders.
Topics: Adrenal Glands; Age Factors; Animals; Anxiety; Behavior, Animal; Chronic Disease; Circadian Rhythm; | 2008 |
A role for macrophage migration inhibitory factor in the neonatal respiratory distress syndrome.
Topics: Animals; Bronchopulmonary Dysplasia; Corticosterone; Disease Models, Animal; Humans; Infant, Newborn | 2008 |
Differential corticosterone responses to stress in the lung in two strains of Flinders rats.
Topics: Animals; Cell Degranulation; Corticosterone; Corticotropin-Releasing Hormone; Diffusion Chambers, Cu | 2008 |
Antidepressant-like effect of onion (Allium cepa L.) powder in a rat behavioral model of depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal | 2008 |
Role of central glucagon-like peptide-1 in hypothalamo-pituitary-adrenocortical facilitation following chronic stress.
Topics: Adrenocorticotropic Hormone; Analysis of Variance; Animals; Behavior, Animal; Body Weight; Chronic D | 2008 |
Investigation of sex differences in behavioural, endocrine, and neural measures following repeated psychological stressor exposure.
Topics: Analysis of Variance; Animals; Behavior, Animal; Body Weight; Brain-Derived Neurotrophic Factor; Cor | 2008 |
A mouse model of depression induced by repeated corticosterone injections.
Topics: Animals; Body Weight; Corticosterone; Depression; Disease Models, Animal; Hindlimb Suspension; Hippo | 2008 |
Prominently decreased hippocampal neurogenesis in a spontaneous model of type 1 diabetes, the nonobese diabetic mouse.
Topics: Age Factors; Analysis of Variance; Animals; Bromodeoxyuridine; Cell Count; Cell Proliferation; Corti | 2008 |
Differential response of TRHergic neurons of the hypothalamic paraventricular nucleus (PVN) in female animals submitted to food-restriction or dehydration-induced anorexia and cold exposure.
Topics: Adaptation, Physiological; Aminopeptidases; Animals; Anorexia; Anxiety; Appetite Regulation; Body Co | 2008 |
Overexpression of human selenoprotein M differentially regulates the concentrations of antioxidants and H2O2, the activity of antioxidant enzymes, and the composition of white blood cells in a transgenic rat.
Topics: Animals; Animals, Genetically Modified; Antioxidants; Corticosterone; Cytomegalovirus; Disease Model | 2008 |
Immune challenge induces differential corticosterone and interleukin-6 responsiveness in rats bred for extremes in anxiety-related behavior.
Topics: Adrenocorticotropic Hormone; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Body Weight; | 2008 |
Effects of treadmill exercise on hypoactivity of the hypothalamo-pituitary-adrenal axis induced by chronic administration of corticosterone in rats.
Topics: Adrenocorticotropic Hormone; Animals; Chronic Disease; Corticosterone; Corticotropin-Releasing Hormo | 2008 |
Disruption of the CRF(2) receptor pathway decreases the somatic expression of opiate withdrawal.
Topics: Animals; Brain; Brain Chemistry; Corticosterone; Disease Models, Animal; Down-Regulation; Female; Ge | 2008 |
Lithium blocks stress-induced changes in depressive-like behavior and hippocampal cell fate: the role of glycogen-synthase-kinase-3beta.
Topics: Adrenal Glands; Animals; Antimanic Agents; Behavior, Animal; Body Weight; Cell Proliferation; Cell S | 2008 |
Metyrapone reveals that previous chronic stress differentially impairs hippocampal-dependent memory.
Topics: Animals; Atrophy; Behavior, Animal; Chronic Disease; Conditioning, Psychological; Corticosterone; Cu | 2001 |
Influence of age on the development of immunological lung response in intrauterine undernourishment.
Topics: Age Factors; Animals; Bronchoalveolar Lavage Fluid; Corticosterone; Disease Models, Animal; Female; | 2008 |
Wheel-running in a transgenic mouse model of Alzheimer's disease: protection or symptom?
Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Corticoster | 2008 |
Increased depressive behaviour in females and heightened corticosterone release in males to swim stress after adolescent social stress in rats.
Topics: Analysis of Variance; Animals; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; | 2008 |
Sialoadenectomy enhances hepatic injury induced by lipopolysaccharide/galactosamine in mice.
Topics: Adrenal Glands; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induce | 2008 |
Gene expression patterns in brain cortex of three different animal models of depression.
Topics: Adrenergic Uptake Inhibitors; Animals; Anti-Inflammatory Agents; Brain Chemistry; Cerebral Cortex; C | 2008 |
Lasting syndrome of depression produced by reduction in serotonin uptake during postnatal development: evidence from sleep, stress, and behavior.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Animals, Newborn; Antidepress | 2008 |
Acute predator stress impairs the consolidation and retrieval of hippocampus-dependent memory in male and female rats.
Topics: Animals; Corticosterone; Disease Models, Animal; Female; Hippocampus; Learning; Male; Memory Disorde | 2008 |
[Effect of Herba Epimedil Brevicornus and prepared Radix Rehmannia on glucocorticoid receptor in glucocorticoid receptor down-regulated rats].
Topics: Animals; Corticosterone; Disease Models, Animal; Down-Regulation; Drugs, Chinese Herbal; Epimedium; | 2008 |
Application of experimental stressors in laboratory rodents.
Topics: Acoustic Stimulation; Adrenocorticotropic Hormone; Animals; Behavior, Animal; Corticosterone; Diseas | 2006 |
Characterization of the vulnerability to repeated stress in Fischer 344 rats: possible involvement of microRNA-mediated down-regulation of the glucocorticoid receptor.
Topics: Animals; Anxiety; Blotting, Northern; Blotting, Western; Body Weight; Brain; Cell Proliferation; Cor | 2008 |
Modeling corticosteroid effects in a rat model of rheumatoid arthritis II: mechanistic pharmacodynamic model for dexamethasone effects in Lewis rats with collagen-induced arthritis.
Topics: Animals; Arthritis, Rheumatoid; Body Weight; Bone Density; Collagen Type II; Corticosterone; Dexamet | 2008 |
Modeling corticosteroid effects in a rat model of rheumatoid arthritis I: mechanistic disease progression model for the time course of collagen-induced arthritis in Lewis rats.
Topics: Animals; Arthritis, Rheumatoid; Body Weight; Bone Density; Collagen Type II; Corticosterone; Disease | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chrom | 2008 |
Altered hypothalamus-pituitary-adrenal gland axis regulation in the expanded CGG-repeat mouse model for fragile X-associated tremor/ataxia syndrome.
Topics: Adaptation, Psychological; Animals; Cerebellar Ataxia; Corticosterone; Disease Models, Animal; DNA R | 2008 |
RU486 did not exacerbate cytokine release in mice challenged with LPS nor in db/db mice.
Topics: Adrenocorticotropic Hormone; Animals; Blood Glucose; Chemokine CCL2; Corticosterone; Diabetes Mellit | 2008 |
Exercise reverses chronic stress-induced Bax oligomer formation in the cerebral cortex.
Topics: Animals; Anti-Inflammatory Agents; bcl-2-Associated X Protein; Behavior, Animal; Cerebral Cortex; Co | 2008 |
ACTH-induced hypertension is dependent on the ouabain-binding site of the alpha2-Na+-K+-ATPase subunit.
Topics: Adrenergic beta-Agonists; Adrenocorticotropic Hormone; Aldosterone; Animals; Binding Sites; Blood Pr | 2008 |
Mice selected for high versus low stress reactivity: a new animal model for affective disorders.
Topics: Adaptation, Psychological; Animals; Breeding; Corticosterone; Disease Models, Animal; Female; Gene E | 2008 |
Induction of hepatic tyrosine aminotransferase by physiological stress: relation to endogenous glucocorticoid secretion and cytosol receptor depletion.
Topics: Adrenalectomy; Animals; Corticosterone; Cytosol; Disease Models, Animal; Enzyme Induction; Glucocort | 1980 |
Regulation of hepatic tyrosine aminotransferase in genetically obese rats.
Topics: Adrenalectomy; Aging; Amino Acids; Animals; Corticosterone; Diet; Disease Models, Animal; Enzyme Act | 1983 |
Hormonal influences on chemical carcinogenesis: studies with the aflatoxin B1 hepatocarcinoma model in the rat.
Topics: Adenoma, Bile Duct; Adrenal Cortex; Adrenocorticotropic Hormone; Aflatoxins; Animals; Corticosterone | 1980 |
Decreased adrenal responsiveness to angiotensin II: a defect present in spontaneously hypertensive rats. A possible model of human essential hypertension.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Corticosterone; Disease Models, Animal; Female | 1982 |
[Studies on magnesium. 2. Effect of magnesium chloride and magnesium aspartate hydrochloride on stress reactions].
Topics: Animals; Aspartic Acid; Catecholamines; Corticosterone; Disease Models, Animal; Magnesium; Magnesium | 1984 |
[Studies on magnesium. 3. Effect of magnesium aspartate hydrochloride on stress reactions in magnesium-deficient animals].
Topics: Animals; Aspartic Acid; Catecholamines; Corticosterone; Disease Models, Animal; Magnesium; Magnesium | 1984 |
Effect of chronic methadone administration on neuroendocrine function in developing rats.
Topics: Age Factors; Animals; Body Weight; Corticosterone; Disease Models, Animal; Female; Growth Hormone; L | 1984 |
Schedule-induced self injection of drugs.
Topics: Alcoholism; Animals; Cocaine; Conditioning, Operant; Corticosterone; Disease Models, Animal; Heroin | 1984 |
Effects of zometapine, a structurally novel antidepressant, in an animal model of depression.
Topics: Animals; Antidepressive Agents; Azepines; Corticosterone; Defecation; Depression; Disease Models, An | 1984 |
The stress of intruding: reduction by chlordiazepoxide.
Topics: Aggression; Agonistic Behavior; Animals; Chlordiazepoxide; Corticosterone; Disease Models, Animal; R | 1984 |
Animal model of depression: tests of three structurally and pharmacologically novel antidepressant compounds.
Topics: Animals; Antidepressive Agents; Bupropion; Corticosterone; Depressive Disorder; Disease Models, Anim | 1982 |
[Adrenal cortex transplantation. Animal experimental models for the human Cushing and Conn syndromes--clinical aspects of adrenal cortex transplantation].
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Animals; Corticosterone; Cushing Syndrome; Di | 1980 |
Drug evaluation in muscular dystrophy of the chicken.
Topics: Animals; Body Weight; Chickens; Corticosterone; Disease Models, Animal; Dose-Response Relationship, | 1982 |
[Biochemical study of the animal model depression induced by tetrabenazine (author's transl)].
Topics: Animals; Behavior; Brain; Corticosterone; Depressive Disorder; Disease Models, Animal; Humans; Male; | 1980 |
Effect of chronic intoxication and naloxone on the ethanol-induced increase in plasma corticosterone.
Topics: Alcoholism; Animals; Corticosterone; Disease Models, Animal; Ethanol; Humans; Male; Naloxone; Rats; | 1981 |
Acute and chronic stress effects on open field activity in the rat: implications for a model of depression.
Topics: Acute Disease; Animals; Chronic Disease; Corticosterone; Depression; Disease Models, Animal; Humans; | 1981 |
Further studies on a novel animal model of depression: therapeutic effects of a tricyclic antidepressant.
Topics: Acute Disease; Animals; Chronic Disease; Corticosterone; Defecation; Depression; Disease Models, Ani | 1981 |
Amphetamine and tranylcypromine in an animal model of depression: pharmacological specificity of the reversal effect.
Topics: Amphetamine; Animals; Chronic Disease; Corticosterone; Defecation; Depression; Disease Models, Anima | 1981 |
Animal model of depression: effects of electroconvulsive shock therapy.
Topics: Animals; Corticosterone; Defecation; Depression; Disease Models, Animal; Electroconvulsive Therapy; | 1981 |
Amitriptyline and scopolamine in an animal model of depression.
Topics: Amitriptyline; Animals; Antidepressive Agents; Corticosterone; Defecation; Depression; Disease Model | 1981 |
Further analysis of the specificity of a novel animal model of depression--effects of an antihistaminic, antipsychotic and anxiolytic compound.
Topics: Animals; Corticosterone; Depressive Disorder; Disease Models, Animal; Exploratory Behavior; Haloperi | 1982 |
Is feminization in alcoholic men due in part to portal hypertension: a rat model.
Topics: Animals; Corticosterone; Disease Models, Animal; Estradiol; Estrone; Ethanol; Feminization; Humans; | 1980 |
Role of plasma arginine vasopressin in the impaired water diuresis of isolated glucocorticoid deficiency in the rat.
Topics: Adrenal Glands; Animals; Arginine Vasopressin; Corticosterone; Disease Models, Animal; Diuresis; Glo | 1980 |
The role of endogenous glucocorticoids in rat experimental models of acute pancreatitis.
Topics: Acute Disease; Adrenal Cortex; Adrenalectomy; Amylases; Animals; Ceruletide; Corticosterone; Disease | 1995 |
Immunoregulation and drug treatment in chronic relapsing experimental allergic encephalomyelitis in the Lewis rat.
Topics: Animals; Autoimmune Diseases; Concanavalin A; Corticosterone; Cyclosporine; Dexamethasone; Disease M | 1995 |
Changes in some parameters of the immune response in rats after cold stress.
Topics: Adrenocorticotropic Hormone; Animals; B-Lymphocytes; Cold Temperature; Corticosterone; Disease Model | 1994 |
In vivo unaltered muscle protein synthesis in experimental chronic metabolic acidosis.
Topics: Acidosis; Animals; Chronic Disease; Corticosterone; Disease Models, Animal; Growth Disorders; Insuli | 1994 |
Socially defeated male rats display a blunted adrenocortical response to a low dose of 8-OH-DPAT.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenal Cortex; Aggression; Animals; Behavior, Animal; Cardi | 1995 |
ACTH does not control neonatal seizures induced by administration of exogenous corticotropin-releasing hormone.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Corticotropin-Releasing Hormone; Disease Model | 1995 |
Persistent stress-induced sensitization of adrenocortical and startle responses.
Topics: Acoustic Stimulation; Adrenal Cortex; Animals; Arousal; Body Weight; Corticosterone; Disease Models, | 1994 |
Quantitative properties of plasma corticosterone elevation induced by naloxone-precipitated withdrawal in morphine-dependent rats.
Topics: Analysis of Variance; Animals; Body Weight; Corticosterone; Disease Models, Animal; Dose-Response Re | 1994 |
Alteration in circadian rhythm of plasma corticosterone in rats following sociopsychological stress induced by communication box.
Topics: Animals; Behavior, Animal; Body Weight; Circadian Rhythm; Corticosterone; Disease Models, Animal; El | 1995 |
Diabetic GK rat plasma but not normal Wistar rat plasma induces insulin-stimulated DNA synthesis in primary cultured smooth muscle cells in GK rat aorta.
Topics: Animals; Aorta, Thoracic; Cells, Cultured; Corticosterone; Diabetes Mellitus, Type 2; Disease Models | 1994 |
Ultrasound vocalization is not related to corticosterone response in isolated rat pups.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Animals, Newborn; Anxiety; Buspirone; Corticosteron | 1994 |
Susceptibility to adjuvant arthritis: relative importance of adrenal activity and bacterial flora.
Topics: Adrenal Glands; Animals; Antigens, Bacterial; Apomorphine; Arthritis, Experimental; Bacteria; Cortic | 1994 |
[The interrelationship between inflammation and the stress reaction].
Topics: Animals; Corticosterone; Disease Models, Animal; Eosinophils; Inflammation; Insulin; Leukocyte Count | 1993 |
Effects of cytokine application on glucocorticoid secretion in an animal model for systemic scleroderma.
Topics: Adrenocorticotropic Hormone; Animals; Autoimmune Diseases; Biological Factors; Cells, Cultured; Chic | 1993 |
Opioids and corticosteroids involvement in the regulation of the neocortical spindling episodes in DBA/2J mice.
Topics: Adrenal Cortex; Animals; Cerebral Cortex; Corticosterone; Cycloheximide; Dexamethasone; Disease Mode | 1993 |
Regional fat distribution and metabolism in a new mouse model (C57BL/6J) of non-insulin-dependent diabetes mellitus.
Topics: Adipose Tissue; Analysis of Variance; Animals; Blood Glucose; Body Constitution; Body Weight; Choles | 1993 |
[The action of defensins on the corticosterone level of the blood and on the immune response in stress].
Topics: Animals; Antibody Formation; Blood Proteins; Corticosterone; Defensins; Disease Models, Animal; Immu | 1993 |
Steroid effects on brain functions: an example of the action of glucocorticoids on central dopaminergic and neurotensinergic systems.
Topics: Adrenocorticotropic Hormone; Aging; Animals; Brain; Cell Death; Corticosterone; Disease Models, Anim | 1995 |
Delayed startle sensitization distinguishes rats exposed to one or three stress sessions: further evidence toward an animal model of PTSD.
Topics: Animals; Arousal; Corticosterone; Disease Models, Animal; Electroshock; Male; Rats; Rats, Sprague-Da | 1995 |
Effect of stress on cochlear glucocorticoid protein. II. Restraint.
Topics: Analysis of Variance; Animals; Cochlea; Corticosterone; Disease Models, Animal; Enzyme-Linked Immuno | 1995 |
Derangement in stress response of apolipoprotein E-deficient mice.
Topics: Alzheimer Disease; Analysis of Variance; Animals; Apolipoproteins E; Corticosterone; Disease Models, | 1996 |
The 21-aminosteroid U-74389F increases the number of glial fibrillary acidic protein-expressing astrocytes in the spinal cord of control and Wobbler mice.
Topics: Adrenalectomy; Amyotrophic Lateral Sclerosis; Animals; Astrocytes; Binding, Competitive; Cell Divisi | 1996 |
Fawn-hooded rats show enhanced active behaviour in the forced swimming test, with no evidence for pituitary-adrenal axis hyperactivity.
Topics: Adrenal Glands; Animals; Behavior, Animal; Corticosterone; Depressive Disorder; Disease Models, Anim | 1996 |
Is there a no-effect dose for corticosteroid-induced cleft palate? The contribution of endogenous corticosterone to the incidence of cleft palate in mice.
Topics: Adrenal Glands; Adrenalectomy; Animals; Cleft Palate; Corticosterone; Disease Models, Animal; Dose-R | 1996 |
Apoptosis of T cells and macrophages in the central nervous system of intact and adrenalectomized Lewis rats during experimental allergic encephalomyelitis.
Topics: Adrenalectomy; Animals; Apoptosis; Cell Count; Central Nervous System; Corticosterone; Disease Model | 1996 |
Suppression of splenic natural killer cell activity in a mouse model for binge drinking. II. Role of the neuroendocrine system.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alcoholism; Animals; Azides; Benzodiazepi | 1996 |
Forced swimming behavior is not related to the corticosterone levels achieved in the test: a study with four inbred rat strains.
Topics: Animals; Arousal; Corticosterone; Disease Models, Animal; Emotions; Escape Reaction; Helplessness, L | 1996 |
Metabolic and endocrine effects of interleukin-1 in obese, diabetic Zucker fa/fa rats.
Topics: Animals; Blood Glucose; Cholesterol; Corticosterone; Diabetes Mellitus; Diabetes Mellitus, Type 2; D | 1996 |
Abnormal corticosterone regulation in an immature rat model of continuous chronic stress.
Topics: Animals; Animals, Newborn; Arousal; Corticosterone; Disease Models, Animal; Female; Hypothalamo-Hypo | 1996 |
Social isolation in animal models of relevance to neuropsychiatric disorders.
Topics: Animals; Arousal; Arvicolinae; Body Weight; Corticosterone; Depressive Disorder; Disease Models, Ani | 1996 |
Sex differences in response to exogenous corticosterone: a rat model of hypercortisolemia.
Topics: Adrenocorticotropic Hormone; Animals; Circadian Rhythm; Corticosterone; Darkness; Disease Models, An | 1996 |
Effect of Ocimum sanctum Linn on noise induced changes in plasma corticosterone level.
Topics: Animals; Behavior, Animal; Corticosterone; Disease Models, Animal; Drinking; Eating; Ethanol; India; | 1997 |
Glucocorticoid receptors and actions in the spinal cord of the Wobbler mouse, a model for neurodegenerative diseases.
Topics: Amyotrophic Lateral Sclerosis; Animals; Astrocytes; Cell Division; Corticosterone; Dexamethasone; Di | 1997 |
Plasma catecholamine and corticosterone levels during manual restraint in chicks from a high and low feather pecking line of laying hens.
Topics: Animals; Behavior, Animal; Catecholamines; Chickens; Corticosterone; Disease Models, Animal; Female; | 1997 |
Chronic treatment with desipramine: effect on endocrine and behavioral responses induced by inescapable stress.
Topics: Animals; Behavior, Animal; Corticosterone; Desipramine; Disease Models, Animal; Escape Reaction; Mal | 1997 |
Regulation of chronic relapsing experimental allergic encephalomyelitis by endogenous and exogenous glucocorticoids.
Topics: Animals; Chronic Disease; Corticosterone; Dexamethasone; Disease Models, Animal; Encephalomyelitis, | 1997 |
Targeted disruption of the mouse gene encoding steroidogenic acute regulatory protein provides insights into congenital lipoid adrenal hyperplasia.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormon | 1997 |
Overexpression of Agrt leads to obesity in transgenic mice.
Topics: Actins; Adipose Tissue; Agouti-Related Protein; Animals; Body Weight; Corticosterone; Disease Models | 1997 |
Forced swim test-induced endocrine and immune changes in the rat: effect of subacute desipramine treatment.
Topics: Adrenal Glands; Animals; Antidepressive Agents, Tricyclic; Ascorbic Acid; Corticosterone; Depression | 1998 |
Testosterone and/or low estradiol: normally required but harmful immunologically for males after trauma-hemorrhage.
Topics: Animals; Corticosterone; Dihydrotestosterone; Disease Models, Animal; Estradiol; Female; Injections, | 1998 |
Thermal injury induces thymocyte apoptosis in the rat.
Topics: Adrenalectomy; Animals; Apoptosis; Burns; Corticosterone; Disease Models, Animal; Glucocorticoids; G | 1998 |
[Influence of chronic variable stress (CVS) on the association of glucocorticoid receptor with heat-shock protein (HSP) 90 in rat hippocampus].
Topics: Animals; Cell Nucleus; Chronic Disease; Corticosterone; Cytosol; Depressive Disorder, Major; Dexamet | 1997 |
Cold stress facilitates calcium mobilization from bone in an ovariectomized rat model of osteoporosis.
Topics: Alkaline Phosphatase; Animals; Calcium; Calcium-Transporting ATPases; Cold Temperature; Corticostero | 1998 |
Orchiectomy and response to testosterone in the development of obesity in young Otsuka-Long-Evans-Tokushima Fatty (OLETF) rats.
Topics: Animals; Base Sequence; Blood Glucose; Cohort Studies; Corticosterone; Diabetes Mellitus, Type 2; Di | 1998 |
Effects of bilateral olfactory bulbectomy on circadian rhythms of ACTH, corticosterone, motor activity and body temperature in male rats.
Topics: Adrenocorticotropic Hormone; Animals; Body Temperature Regulation; Circadian Rhythm; Corticosterone; | 1997 |
Enhanced morphine-induced behavioural effects and dopamine release in the nucleus accumbens in a transgenic mouse model of impaired glucocorticoid (type II) receptor function: influence of long-term treatment with the antidepressant moclobemide.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Benzamides; Corticosterone; Disease Models, Animal | 1998 |
Prospective randomized study of stress and immune response after laparoscopic vs conventional colonic resection.
Topics: Animals; Colectomy; Corticosterone; Disease Models, Animal; Evaluation Studies as Topic; Interleukin | 1998 |
Intracerebroventricular injection-induced increase in plasma corticosterone levels in the mouse: a stress model.
Topics: Animals; Corticosterone; Corticotropin-Releasing Hormone; Disease Models, Animal; Injections, Intrav | 1998 |
Bromocriptine/SKF38393 ameliorates islet dysfunction in the diabetic (db/db) mouse.
Topics: Animals; Blood Glucose; Bromocriptine; Corticosterone; Diabetes Mellitus, Type 2; Disease Models, An | 1998 |
Mechanism of suppressed neutrophil mobilization in a mouse model for binge drinking: role of glucocorticoids.
Topics: Alcohol Drinking; Animals; Corticosterone; Disease Models, Animal; Ethanol; Female; Inflammation; Ma | 1998 |
Ethanol-induced activation of the hypothalamic-pituitary-adrenal axis in a mouse model for binge drinking: role of Ro15-4513-sensitive gamma aminobutyric acid receptors, tolerance, and relevance to humans.
Topics: Affinity Labels; Animals; Azides; Benzodiazepines; Corticosterone; Disease Models, Animal; Dose-Resp | 1998 |
[A model of chronic situational stress and its effect on the rate of aging and the longevity of rats].
Topics: Adaptation, Physiological; Aging; Animals; Chronic Disease; Corticosterone; Disease Models, Animal; | 1998 |
The effect of repeated exposure to forced swimming on extracellular levels of 5-hydroxytryptamine in the rat.
Topics: Animals; Behavior, Animal; Corpus Striatum; Corticosterone; Depression; Disease Models, Animal; Extr | 1998 |
Serial transplants of DMBA-induced mammary tumors in Fischer rats as a model system for human breast cancer. VI. The role of different forms of tumor-associated stress for the regulation of pineal melatonin secretion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Biopterins; Breast Neoplasms; Catecholami | 1999 |
Increased neurodegeneration during ageing in mice lacking high-affinity nicotine receptors.
Topics: Aging; Alzheimer Disease; Animals; Atrophy; Biomarkers; Brain; Corticosterone; Disease Models, Anima | 1999 |
The effect of stress on the inflammatory response to Porphyromonas gingivalis in a mouse subcutaneous chamber model.
Topics: Animals; Anti-Inflammatory Agents; Bacteroidaceae Infections; Cell Movement; Cold Temperature; Corti | 1999 |
Evaluation of signals activating ubiquitin-proteasome proteolysis in a model of muscle wasting.
Topics: Acidosis; Adrenalectomy; Animals; Corticosterone; Cysteine Endopeptidases; Dexamethasone; Diabetes M | 1999 |
Adrenomedullary function is severely impaired in 21-hydroxylase-deficient mice.
Topics: Adrenal Hyperplasia, Congenital; Adrenal Medulla; Animals; Base Sequence; Catecholamines; Chromaffin | 1999 |
Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; alpha-MSH; Animals; Catecholamines; Cortic | 1999 |
Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety.
Topics: Adrenal Glands; Age Factors; Animals; Anxiety; Brain; Corticosterone; Cushing Syndrome; Disease Mode | 1999 |
Abnormalities of hypothalamic-pituitary-adrenal and hypothalamic-somatotrophic axes in Fawn-Hooded rats.
Topics: Adrenocorticotropic Hormone; Animals; Brain; Corticosterone; Corticotropin-Releasing Hormone; Diseas | 1999 |
[Effect of aged garlic extract (AGE) on hyperglycemia induced by immobilization stress in mice].
Topics: Adrenal Glands; Animals; Blood Glucose; Corticosterone; Disease Models, Animal; Garlic; Hyperglycemi | 1999 |
Olfactory bulbectomy provokes a suppression of interleukin-1beta and tumour necrosis factor-alpha production in response to an in vivo challenge with lipopolysaccharide: effect of chronic desipramine treatment.
Topics: Adrenal Cortex; Animals; Antidepressive Agents, Tricyclic; Ascorbic Acid; Behavior, Animal; Corticos | 2000 |
Pretreatment of mice with lipopolysaccharide (LPS) or IL-1beta exerts dose-dependent opposite effects on Shiga toxin-2 lethality.
Topics: Animals; Bacterial Toxins; Child; Corticosterone; Disease Models, Animal; Dose-Response Relationship | 2000 |
Early androgen treatment decreases cognitive function and catecholamine innervation in an animal model of ADHD.
Topics: Adrenocorticotropic Hormone; Animals; Attention Deficit Disorder with Hyperactivity; Brain Mapping; | 2000 |
Differential effects of hemorrhage and LPS on tissue TNF-alpha, IL-1 and associate neuro-hormonal and opioid alterations.
Topics: Animals; beta-Endorphin; Blood Pressure; Catecholamines; Corticosterone; Disease Models, Animal; Epi | 2000 |
Glucocorticoid-induced, caspase-dependent organ apoptosis early after burn injury.
Topics: Animals; Antibodies, Monoclonal; Apoptosis; Burns; Caspase 3; Caspases; CD4-Positive T-Lymphocytes; | 2000 |
Impact of diazepam on pineal-adrenal axis in an avian model.
Topics: Adrenal Glands; Animals; Columbidae; Corticosterone; Diazepam; Disease Models, Animal; Epinephrine; | 2000 |
Influence of anterodorsal thalamic nuclei on the hypophyseal-adrenal axis and cardiac beta receptors in rats submitted to variable chronic stress.
Topics: Adrenocorticotropic Hormone; Animals; Anterior Thalamic Nuclei; Chronic Disease; Corticosterone; Dis | 1999 |
Alterations in glucose-6-phosphatase gene expression in sepsis.
Topics: Animals; Blotting, Northern; Corticosterone; Disease Models, Animal; Gene Expression Regulation, Enz | 2000 |
Experimental paracoccidioidomycosis in high and low antibody responder mice of Selection IV-A.
Topics: Adrenal Glands; Animals; Antibodies, Fungal; Antibody Specificity; Corticosterone; Disease Models, A | 2000 |
Effects of experimental hypothyroidism on the development of the hypothalamo-pituitary-adrenal axis in the rat.
Topics: Administration, Oral; Adrenocorticotropic Hormone; Aging; Animals; Arginine Vasopressin; Corticoster | 2000 |
Deviant forms of aggression in glucocorticoid hyporeactive rats: a model for 'pathological' aggression?
Topics: Adrenalectomy; Aggression; Animals; Anti-Inflammatory Agents; Behavior, Animal; Corticosterone; Dise | 2001 |
Neuroendocrine and behavioral effects of repetitive transcranial magnetic stimulation in a psychopathological animal model are suggestive of antidepressant-like effects.
Topics: Adaptation, Psychological; Adrenocorticotropic Hormone; Animals; Anxiety; Behavior, Animal; Computer | 2001 |
Stereotaxic delivery of corticosterone to the amygdala modulates colonic sensitivity in rats.
Topics: Acetic Acid; Amygdala; Animals; Anxiety; Behavior, Animal; Cholesterol; Colon; Colonic Diseases, Fun | 2001 |
An experimental model of stress-induced immunosuppression produced by electrical stimulation of the brain in the rat.
Topics: Animals; Antibodies; Corticosterone; Disease Models, Animal; Electric Stimulation; Erythrocytes; Hyp | 2001 |
Social stress increases the susceptibility to endotoxic shock.
Topics: Animals; Cell Division; Cell Separation; Corticosterone; Disease Models, Animal; Disease Susceptibil | 2001 |
Exposure to repeated low-level formaldehyde in rats increases basal corticosterone levels and enhances the corticosterone response to subsequent formaldehyde.
Topics: Animals; Corticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administrati | 2001 |
Adrenal insufficiency during the late stage of polymicrobial sepsis.
Topics: Adrenal Glands; Adrenal Insufficiency; Adrenocorticotropic Hormone; Animals; Bacterial Infections; C | 2001 |
Opiate modulation of hemodynamic, hormonal, and cytokine responses to hemorrhage.
Topics: Adrenocorticotropic Hormone; Animals; Apoptosis; beta-Endorphin; Blood Pressure; Corticosterone; Cyt | 2001 |
Expression and function of P-glycoprotein in rats with carbon tetrachloride-induced acute hepatic failure.
Topics: Animals; Anti-Inflammatory Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; C | 2001 |
Altered hormone levels and circadian rhythm of activity in the WKY rat, a putative animal model of depression.
Topics: Activity Cycles; Adrenocorticotropic Hormone; Animals; Behavior, Animal; Chronobiology Disorders; Co | 2001 |
Genetic predisposition and the development of posttraumatic stress disorder in an animal model.
Topics: Animals; Brain; Cognition Disorders; Corticosterone; Disease Models, Animal; Genetic Predisposition | 2001 |
Postnatal maternal deprivation produces long-lasting modifications of the stress response, feeding and stress-related behaviour in the rat.
Topics: Adrenocorticotropic Hormone; Animals; Animals, Newborn; Behavior, Animal; Body Weight; Corticosteron | 2001 |
Therapeutic effect of glycyrrhetinic acid in MRL lpr/lpr mice: implications of alteration of corticosteroid metabolism.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Administration, Oral; Animals; Autoimmune Diseases; Body Weig | 2001 |
Gender-dependent differences in latent inhibition following prenatal stress and corticosterone administration.
Topics: Animals; Attention; Brain; Corticosterone; Disease Models, Animal; Female; Humans; Inhibition, Psych | 2001 |
A transgenic model of visceral obesity and the metabolic syndrome.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Abdomen; Adipocytes; Adipose Tissue; Animals; Body Comp | 2001 |
Effects of tapering neonatal dexamethasone on rat growth, neurodevelopment, and stress response.
Topics: Animals; Animals, Newborn; Behavior, Animal; Brain; Corticosterone; Dexamethasone; Disease Models, A | 2002 |
Trypanosoma cruzi: the development of estrus cycle and parasitemia in female mice maintained with or without male pheromones.
Topics: Anestrus; Animals; Chagas Disease; Corticosterone; Disease Models, Animal; Estradiol; Estrous Cycle; | 2001 |
Experimental Chagas disease: the influence of sex and psychoneuroimmunological factors.
Topics: Animals; Behavior, Animal; Chagas Disease; Corticosterone; Disease Models, Animal; Female; Humans; M | 2001 |
Post-stress recovery of pituitary-adrenal hormones and glucose, but not the response during exposure to the stressor, is a marker of stress intensity in highly stressful situations.
Topics: Adrenocorticotropic Hormone; Animals; Biomarkers; Blood Glucose; Corticosterone; Disease Models, Ani | 2002 |
Behavioral, hormonal and histological stress markers of anxiety-separation in postnatal rats are reduced by prepro-thyrotropin-releasing hormone 178-199.
Topics: Adrenocorticotropic Hormone; Animals; Animals, Newborn; Anxiety, Separation; Behavior, Animal; Corti | 2002 |
Neuronal activation and corticotropin-releasing hormone expression in the brain of obese (fa/fa) and lean (fa/?) Zucker rats in response to refeeding.
Topics: Animals; Appetite Regulation; Body Weight; Brain; Brain Stem; Corticosterone; Corticotropin-Releasin | 2002 |
Effects of chronic mild stress on lymphocyte proliferative response. Participation of serum thyroid hormones and corticosterone.
Topics: Animals; Cell Division; Chronic Disease; Concanavalin A; Corticosterone; Disease Models, Animal; Fem | 2002 |
Host circadian clock as a control point in tumor progression.
Topics: Adenocarcinoma; Animals; Body Temperature; Body Weight; Circadian Rhythm; Corticosterone; Disease Mo | 2002 |
The effects of ACTH and adrenocorticosteroids on seizure susceptibility in 15-day-old male rats.
Topics: Adrenocorticotropic Hormone; Aldosterone; Animals; Corticosterone; Dehydroepiandrosterone; Desoxycor | 2002 |
Transplantation of adrenal tissue fragments in a murine model: functional capacities of syngeneic and allogeneic grafts.
Topics: Addison Disease; Adrenal Cortex Hormones; Adrenal Glands; Animals; Corticosterone; Cytochrome P-450 | 2002 |
Social stress exacerbates focal cerebral ischemia in mice.
Topics: Animals; Behavior, Animal; Brain Ischemia; Cognition; Corticosterone; Disease Models, Animal; Diseas | 2002 |
Neither forced running nor forced swimming affect acute pyridostigmine toxicity or brain-regional cholinesterase inhibition in rats.
Topics: Administration, Oral; Animals; Blood-Brain Barrier; Brain; Cholinesterase Inhibitors; Cholinesterase | 2002 |
Sex differences in models of temporal lobe epilepsy: role of testosterone.
Topics: Animals; Behavior, Animal; Brain; Corticosterone; Disease Models, Animal; Epilepsy, Temporal Lobe; E | 2002 |
An opposing role for the adrenals in the hypotensive effects of propranolol in the spontaneously hypertensive rat.
Topics: Adrenal Glands; Adrenalectomy; Animals; Blood Pressure; Corticosterone; Disease Models, Animal; Hear | 1979 |
Development and adult pituitary-adrenal function in female rats injected with morphine during different postnatal periods.
Topics: Age Factors; Animals; Animals, Newborn; Behavior, Animal; Corticosterone; Disease Models, Animal; Ey | 1977 |
Effect of burn injury on glucose turnover in guinea pigs.
Topics: Animals; Blood Pressure; Burns; Cardiac Output; Corticosterone; Disease Models, Animal; Glucagon; Gl | 1977 |
Ultrastructural changes in the coronary vascular system following prolonged emotional stress. An experimental model for the study of coronary vascular disease [proceedings]?
Topics: Animals; Coronary Disease; Coronary Vessels; Corticosterone; Disease Models, Animal; Male; Rats; Str | 1977 |
Multifactorial analysis of chronic hypertension induced by electrolyte-active steroids in trained, unanesthetized dogs.
Topics: Acebutolol; Aldosterone; Animals; Chronic Disease; Clonidine; Corticosterone; Diet, Sodium-Restricte | 1977 |
Effects of limited food intake on the obese-hyperglycemic syndrome.
Topics: Animals; Blood Glucose; Body Composition; Body Height; Body Weight; Bone Development; Corticosterone | 1976 |
Proceedings: Changes in adrenal function in spontaneously hypertensive rats.
Topics: Adrenal Glands; Animals; Corticosterone; Disease Models, Animal; Dopamine beta-Hydroxylase; Epinephr | 1976 |
The adrenal cortex in spontaneously hypertensive rats. A quantitative ultrastructural study.
Topics: Adrenal Cortex; Adrenal Glands; Animals; Body Weight; Corticosterone; Disease Models, Animal; Endopl | 1976 |
Brain amines and models of experimental hypertension.
Topics: Animals; Blood Pressure; Brain Stem; Cerebral Ventricles; Corticosterone; Disease Models, Animal; Do | 1975 |
Proceedings: Corticosterone contents in plasma and adrenal gland of spontaneously hypertensive rat.
Topics: Adrenal Glands; Animals; Corticosterone; Disease Models, Animal; Hypertension; Male; Rats | 1975 |
Hypocitricemic response to surgical stress in rats.
Topics: Animals; Citrates; Corticosterone; Disease Models, Animal; Male; Rats; Stress, Physiological; Surgic | 1975 |
[Adrenal corticosteroid and disease models of hypertension].
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Animals; Corticosterone; Desoxycorticoster | 1992 |
Investigation of ACTH responses of chickens with autoimmune disease.
Topics: Adrenocorticotropic Hormone; Animals; Autoimmune Diseases; Cell Extracts; Chickens; Corticosterone; | 1992 |
[Disease models of steroid-induced hypertension].
Topics: Aldosterone; Animals; Corticosterone; Cushing Syndrome; Desoxycorticosterone; Dexamethasone; Disease | 1992 |
Decrease of testosterone level during an experimental African trypanosomiasis: involvement of a testicular LH receptor desensitization.
Topics: Acute-Phase Reaction; Animals; Blood Glucose; Chorionic Gonadotropin; Corticosterone; Disease Models | 1992 |
Experimental study on adrenal autografts in rats to preserve normal adrenocortical function after bilateral adrenalectomy.
Topics: Adrenal Glands; Adrenalectomy; Animals; Corticosterone; Disease Models, Animal; Male; Rats; Rats, In | 1992 |
Molecular response to surgical stress: specific and simultaneous heat shock protein induction in the adrenal cortex, aorta, and vena cava.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Aorta; Base Sequence; Corticosterone; Disease | 1991 |
Studies on the thymus in Chagas' disease. II. Thymocyte subset fluctuations in Trypanosoma cruzi-infected mice: relationship to stress.
Topics: Animals; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; B-Lymphocytes; CD3 Complex; CD4 | 1991 |
Alterations in the hypothalamic-pituitary-adrenal axis in a proposed animal model of depression with genetic muscarinic supersensitivity.
Topics: Adrenocorticotropic Hormone; Animals; Brain Chemistry; Corticosterone; Corticotropin-Releasing Hormo | 1991 |
[Changes in plasma levels of corticosterone, testosterone and estradiol and their receptors in the lung cytosol in experimental fibrosing process in the lungs].
Topics: Animals; Corticosterone; Cytosol; Disease Models, Animal; Estradiol; Lung; Male; Pulmonary Fibrosis; | 1991 |
Sex and strain differences in the circadian rhythm fluctuation of endocrine and immune function in the rat: implications for rodent models of autoimmune disease.
Topics: Animals; Autoimmune Diseases; Cell Count; Circadian Rhythm; Corticosterone; Disease Models, Animal; | 1991 |
Hydrazine sulfate protects D-galactosamine-sensitized mice against endotoxin and tumor necrosis factor/cachectin lethality: evidence of a role for the pituitary.
Topics: Animals; Blood Glucose; Corticosterone; Disease Models, Animal; Drug Hypersensitivity; Endotoxins; F | 1991 |
[Plasma corticosterone level in experimental mild cranio-cerebral injury in rabbits].
Topics: Animals; Brain Concussion; Corticosterone; Disease Models, Animal; Male; Rabbits; Stress, Physiologi | 1991 |
Hormonal influence on breast cancer: elucidation with a mouse model.
Topics: Animals; Corticosterone; Disease Models, Animal; Estradiol; Female; Male; Mammary Neoplasms, Experim | 1991 |
[Studies on the influence of acute maternal stress on the fetal endocrine system in late gestation of rats].
Topics: Acute Disease; Adrenocorticotropic Hormone; Animals; beta-Endorphin; Corticosterone; Disease Models, | 1990 |
Analysis of the immune-encodrine feedback loop in the avian system and its alteration in chickens with spontaneous autoimmune thyroiditis.
Topics: Adrenal Glands; Animals; Autoimmune Diseases; Chickens; Chromatography, Affinity; Corticosterone; Co | 1990 |
Effects of bilateral adrenalectomy on the induction of learned helplessness behavior.
Topics: Adrenalectomy; Animals; Corticosterone; Depression; Disease Models, Animal; Electroshock; Escape Rea | 1990 |
Ascites in growing broilers: a research model.
Topics: Altitude; Animals; Ascites; Body Weight; Chickens; Corticosterone; Disease Models, Animal; Erythrocy | 1990 |
Neuropharmacological and physiological validation of a computer-controlled two-compartment black and white box for the assessment of anxiety.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Body Temperature; Computers; Corticosterone | 1989 |
Adrenocortical and behavioral responses to repeated stressors: toward an animal model of chronic stress and stress-related mental illness.
Topics: Adrenal Cortex; Animals; Arousal; Behavior, Animal; Body Weight; Corticosterone; Disease Models, Ani | 1989 |
Fatty liver and plasma corticosterone levels in chronically alcohol- and pair-fed rats.
Topics: Alcoholism; Animals; Cholesterol Esters; Corticosterone; Dexamethasone; Disease Models, Animal; Fatt | 1989 |
Animal model of anxiety: effect of acute diazepam treatment in the older adult genetically hypertensive rats of Koletsky type and in the older adult rats of Wistar strain.
Topics: Age Factors; Animals; Anxiety; Behavior, Animal; Body Temperature; Corticosterone; Diazepam; Disease | 1989 |
Differential sensitivity to dexamethasone suppression in an animal model of the DST.
Topics: Animals; Corticosterone; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; He | 1989 |
[Effect of hyperbaric oxygenation on the corticosterone content of the blood in experimental acute respiratory distress syndrome].
Topics: Acute Disease; Animals; Corticosterone; Disease Models, Animal; Hyperbaric Oxygenation; Oleic Acids; | 1989 |
5-Hydroxytryptamine and corticosterone in an animal model of depression.
Topics: Animals; Corticosterone; Depression; Disease Models, Animal; Rats; Restraint, Physical; Serotonin; S | 1989 |
Pituitary-adrenal response to bacterial endotoxin in developing rats.
Topics: Adrenocorticotropic Hormone; Aging; Animals; Animals, Newborn; Blood Glucose; Corticosterone; Diseas | 1988 |
Anti-opiate (naloxone) suppression of Cushingoid degenerative changes in obese/SHR.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; beta-Endorphin; Blood Pressure; Body Weight; C | 1985 |
The effects of PK 11195, a ligand for benzodiazepine binding sites, in animal tests of anxiety and stress.
Topics: Animals; Anxiety; Benzodiazepinones; Corticosterone; Disease Models, Animal; Drinking Behavior; Isoq | 1985 |
Chronic ethanol ingestion enhances catabolism and muscle protease activity in acutely uremic rats.
Topics: Acute Kidney Injury; Alcoholism; Animals; Blood Urea Nitrogen; Cathepsin B; Corticosterone; Disease | 1988 |
Low doses of L-tryptophan are lethal in rats with adrenal insufficiency.
Topics: Adrenal Insufficiency; Adrenalectomy; Animals; Corticosterone; Disease Models, Animal; Lethal Dose 5 | 1987 |
Interactions amongst factors which influence severity of gastric ulceration in rats.
Topics: Animals; Corticosterone; Disease Models, Animal; Electroshock; Handling, Psychological; Helplessness | 1986 |
Central serotonergic responses and behavioural adaptation to repeated immobilisation: the effect of the corticosterone synthesis inhibitor metyrapone.
Topics: Adaptation, Physiological; Animals; Behavior, Animal; Body Weight; Corticosterone; Disease Models, A | 1985 |
[Pharmacological modification of traumatic edemas in animal experiment and clinic].
Topics: Animals; Anti-Inflammatory Agents; Aprotinin; Chymotrypsin; Corticosterone; Depression, Chemical; Di | 1970 |
A simple trauma model in the rat.
Topics: Animals; Blood Glucose; Blood Urea Nitrogen; Corticosterone; Disease Models, Animal; Potassium; Pseu | 1973 |
Effect of diabetes in pregnancy on rat maternal liver delta 4-3-ketone-steroid reductase.
Topics: Animals; Birth Weight; Blood Glucose; Body Weight; Corticosterone; Diabetes Mellitus; Disease Models | 1974 |
[Adrenal cortex and plasma corticosterone modifications in rats in an experimental model of fatique].
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Corticosterone; Disease Models, Animal; Fatigu | 1971 |
Stress and murine sarcoma virus (Moloney)-induced tumors.
Topics: Adrenocorticotropic Hormone; Aggression; Animals; Corticosterone; Disease Models, Animal; Electrosho | 1972 |
Participation of catecholamines and cortical hormones in the myocardial metabolic adaptation to mechanical overload of the heart.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Animals; Corticosterone; Disease Models, Animal; Epineph | 1972 |
Proceedings: The production of hypertension and the effects of some antihypertensive agents in the conscious unrestrained cat.
Topics: Animals; Antihypertensive Agents; Cats; Cellophane; Clonidine; Corticosterone; Delayed-Action Prepar | 1974 |
Adrenal responsiveness in ageing Brattleboro rats with hereditary diabetes insipidus.
Topics: Adrenal Glands; Animals; Body Weight; Corticosterone; Diabetes Insipidus; Disease Models, Animal; Et | 1974 |
Sympathetic nervous system and deoxycorticosterone-saline hypertension.
Topics: Adrenal Glands; Animals; Corticosterone; Disease Models, Animal; Hydroxydopamines; Hypertension; Rat | 1973 |
Effects of coping behavior in different warning signal conditions on stress pathology in rats.
Topics: Animals; Auditory Perception; Avoidance Learning; Behavior, Animal; Body Weight; Conditioning, Psych | 1971 |
Effects of coping behavior with and without a feedback signal on stress pathology in rats.
Topics: Animals; Auditory Perception; Avoidance Learning; Behavior, Animal; Body Weight; Corticosterone; Dis | 1971 |
Arteriosclerosis in spontaneously hypertensive rats on high fat diet.
Topics: Animals; Arteriosclerosis; Blood Pressure; Blood Proteins; Body Weight; Cholesterol; Corticosterone; | 1970 |
Experimental congenital lipoid adrenal hyperplasia: prevention of anatomic defects produced by aminoglutethimide.
Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Aminoglutethimide; Aniline Compounds; Animals; Anti | 1970 |
Adrenal steroidogenesis in rats bred for susceptibility and resistance to the hypertensive effect of salt.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Analysis of Variance; Animals; Blood Pressure; Body Weight; | 1971 |