corticosterone has been researched along with Depressive Disorder in 213 studies
Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study utilized a translational animal model of maternal depression (based on giving high levels of corticosterone (CORT, 40 mg/kg, s." | 7.91 | Developmental outcomes after gestational antidepressant treatment with sertraline and its discontinuation in an animal model of maternal depression. ( Brummelte, S; Kott, JM; Mooney-Leber, SM, 2019) |
| " Therefore, we tested this hypothesis in the depression model of chronic administration of corticosterone (CORT) in mice and treated the animals daily with liraglutide (5 or 20 nmol/kg ip." | 7.88 | Liraglutide attenuates the depressive- and anxiety-like behaviour in the corticosterone induced depression model via improving hippocampal neural plasticity. ( Birong, L; Christian, H; Feiyu, S; Le, W; Weina, H; Yuhu, N, 2018) |
| " The corticosterone rat model was developed to understand the influence of stress on depression-like symptomatology." | 7.88 | Depression-like behaviors induced by chronic corticosterone exposure via drinking water: Time-course analysis. ( Cui, SY; Cui, XY; Ding, H; Hu, X; Liu, YT; Ye, H; Zhang, YH; Zhao, HL, 2018) |
| " Herein, we have described a mouse model of a depression-like and insulin-resistant (DIR) state induced by the co-treatment of high-fat diet (HFD) and corticosterone (CORT)." | 7.80 | Depression-like behaviors in mice subjected to co-treatment of high-fat diet and corticosterone are ameliorated by AICAR and exercise. ( Ji, L; Li, H; Liu, W; Zhai, X, 2014) |
| "BACKGROUND Depression is a common disorder linked with high levels of chronicity, psycho-social and physical problems, and suicide." | 5.51 | Antidepressive Effects of Taraxacum Officinale in a Mouse Model of Depression Are Due to Inhibition of Corticosterone Levels and Modulation of Mitogen-Activated Protein Kinase Phosphatase-1 (Mkp-1) and Brain-Derived Neurotrophic Factor (Bdnf) Expression. ( Duan, H; Gao, C; Guo, B; Kong, S; Li, D; Liang, X, 2019) |
| "Depression is commonly associated with hypothalamic-pituitary adrenal (HPA) axis dysfunction that primarily manifests as aberrant glucocorticoid secretion." | 5.48 | Differential effects of imipramine and CORT118335 (Glucocorticoid receptor modulator/mineralocorticoid receptor antagonist) on brain-endocrine stress responses and depression-like behavior in female rats. ( Balmer, NJ; Caldwell, JL; Estrada, CM; Ghisays, V; Nguyen, ET; Solomon, MB; Streicher, J, 2018) |
| " At the end of dosing schedule, neurobehavioral tests were conducted; followed by mechanistic evaluation through biochemical analysis, RTPCR and western blot in serum and hippocampus." | 5.48 | Antidepressant activity of vorinostat is associated with amelioration of oxidative stress and inflammation in a corticosterone-induced chronic stress model in mice. ( Js, IC; Kv, A; Lahkar, M; Madhana, RM; Naidu, VGM; Sinha, S, 2018) |
| "Comorbid depression was induced by five inescapable foot-shocks (2mA, 2ms duration) at 10s intervals on days 1, 5, 7, and 10." | 5.46 | Metformin and ascorbic acid combination therapy ameliorates type 2 diabetes mellitus and comorbid depression in rats. ( Kumar, M; Nayak, PK; Shivavedi, N; Tej, GNVC, 2017) |
| "Depression is a common psychopathological disorders." | 5.43 | Zinc and imipramine reverse the depression-like behavior in mice induced by chronic restraint stress. ( Ding, Q; Huang, J; Li, H; Mo, F; Shen, H; Shen, Z; Tian, X; Wang, X, 2016) |
| " This study investigated antidepressant-like effects and possible underlying mechanisms of Lactobacillus paracasei PS23 (PS23), live or heat-killed, in a mouse model of corticosterone-induced depression using fluoxetine as standard drug." | 3.91 | Antidepressant-like activities of live and heat-killed Lactobacillus paracasei PS23 in chronic corticosterone-treated mice and possible mechanisms. ( Cheng, YF; Hsu, CC; Liao, CL; Tsai, YC; Wang, S; Wei, CL; Wu, CC; Yen, JT, 2019) |
| " We then measured the body weight and performed the sucrose preference test, forced swimming test (FST) and open field test to detect the effects of stress on anhedonia and activity." | 3.91 | DNA methylation of the Tacr2 gene in a CUMS model of depression. ( Fu, L; Liu, Z; Wan, Q; Wang, G; Xiang, D; Xiao, J; Xiao, L; Yao, L; Zhu, F, 2019) |
| " This study utilized a translational animal model of maternal depression (based on giving high levels of corticosterone (CORT, 40 mg/kg, s." | 3.91 | Developmental outcomes after gestational antidepressant treatment with sertraline and its discontinuation in an animal model of maternal depression. ( Brummelte, S; Kott, JM; Mooney-Leber, SM, 2019) |
| " Also, they displayed higher levels of blood serum corticosterone, as well as decreased body weight." | 3.88 | Vicarious Social Defeat Stress Induces Depression-Related Outcomes in Female Mice. ( Alipio, JB; Braren, SH; Castillo, SA; Flores-Ramirez, FJ; Garcia-Carachure, I; Hernandez, MA; Iñiguez, SD; Lobo, MK; Riggs, LM; Sanchez, DO; Serrano, PA, 2018) |
| " Therefore, we tested this hypothesis in the depression model of chronic administration of corticosterone (CORT) in mice and treated the animals daily with liraglutide (5 or 20 nmol/kg ip." | 3.88 | Liraglutide attenuates the depressive- and anxiety-like behaviour in the corticosterone induced depression model via improving hippocampal neural plasticity. ( Birong, L; Christian, H; Feiyu, S; Le, W; Weina, H; Yuhu, N, 2018) |
| " The corticosterone rat model was developed to understand the influence of stress on depression-like symptomatology." | 3.88 | Depression-like behaviors induced by chronic corticosterone exposure via drinking water: Time-course analysis. ( Cui, SY; Cui, XY; Ding, H; Hu, X; Liu, YT; Ye, H; Zhang, YH; Zhao, HL, 2018) |
| " MEC prevented CRS-induced depressive-like behavior via increasing sucrose preference, body weight, and forced swim test (FST) struggling and swimming while reducing immobility in FST and hypothalamic-pituitary-adrenal (HPA) axis hyperactivity (adrenal gland weight and serum corticosterone)." | 3.81 | Behavioral effects of nicotinic antagonist mecamylamine in a rat model of depression: prefrontal cortex level of BDNF protein and monoaminergic neurotransmitters. ( Aboul-Fotouh, S, 2015) |
| " Herein, we have described a mouse model of a depression-like and insulin-resistant (DIR) state induced by the co-treatment of high-fat diet (HFD) and corticosterone (CORT)." | 3.80 | Depression-like behaviors in mice subjected to co-treatment of high-fat diet and corticosterone are ameliorated by AICAR and exercise. ( Ji, L; Li, H; Liu, W; Zhai, X, 2014) |
| "We investigated the effect of two well characterized preclinical animal models of depression - repeated injections of corticosterone (CORT) and repeated restraint stress - on markers of GABAergic and glutamatergic activity in the hippocampus and amygdala." | 3.79 | Altered GABAergic and glutamatergic activity within the rat hippocampus and amygdala in rats subjected to repeated corticosterone administration but not restraint stress. ( Caruncho, HJ; Kalynchuk, LE; Lussier, AL; Romay-Tallón, R, 2013) |
| "On the basis of CMS-induced changes of sucrose intake, a reliable measure for anhedonia, rats were divided into "resilient" and "anhedonic" groups." | 3.78 | Chronic mild stress-induced depression-like symptoms in rats and abnormalities in catecholamine uptake in small arteries. ( Aalkjaer, C; Boedtkjer, DB; Bouzinova, EV; Broegger, T; Matchkov, VV; Møller-Nielsen, N; Wiborg, O, 2012) |
| "Developmental deficits in GABAergic inhibition in the forebrain cause behavioral and endocrine abnormalities and selective antidepressant drug responsiveness indicative of anxious-depressive disorders such as melancholic depression, which are frequently characterized by HPA axis hyperactivity and greater efficacy of desipramine versus fluoxetine." | 3.76 | gamma-Aminobutyric acid-type A receptor deficits cause hypothalamic-pituitary-adrenal axis hyperactivity and antidepressant drug sensitivity reminiscent of melancholic forms of depression. ( Andrews, AM; Earnheart, JC; Lal, R; Luellen, BA; Luscher, B; Shen, Q, 2010) |
| " We found that subjecting animals to the chronic stress protocol for 20days resulted in performance deficits in the shuttle-box task and several physiological effects, such as an abnormal adrenal gland weight to body weight (AG/B) ratio and increased thickness of the adrenal cortex as well as elevated serum corticosterone levels and reduced glucocorticoid receptor (GR) mRNA expression." | 3.73 | Curcumin reverses the effects of chronic stress on behavior, the HPA axis, BDNF expression and phosphorylation of CREB. ( Jiang, W; Ku, B; Li, X; Ma, X; Tie, L; Xu, Y; Yao, H, 2006) |
| " Experimentally, the chronic administration of corticosterone (CORT) in rodents has been reported to promote depressive-like behaviors." | 1.72 | Protective effect of Myrcia pubipetala Miq. against the alterations in oxidative stress parameters in an animal model of depression induced by corticosterone. ( Alberton, MD; Barauna, SC; de Lima, DD; Lopes, BG; Magro, DDD; Rocha, FE; Shuster, AL; Wayszceyk, S, 2022) |
| "BACKGROUND Depression is a common disorder linked with high levels of chronicity, psycho-social and physical problems, and suicide." | 1.51 | Antidepressive Effects of Taraxacum Officinale in a Mouse Model of Depression Are Due to Inhibition of Corticosterone Levels and Modulation of Mitogen-Activated Protein Kinase Phosphatase-1 (Mkp-1) and Brain-Derived Neurotrophic Factor (Bdnf) Expression. ( Duan, H; Gao, C; Guo, B; Kong, S; Li, D; Liang, X, 2019) |
| " Furthermore, chronic administration of corticosterone significantly increased Dkk-1 expression, decreased the phosphorylation of Ser9 of GSK-3β, and resulted in the impairment of hippocampal learning and memory." | 1.48 | Modulation of GSK-3β/β-Catenin Signaling Contributes to Learning and Memory Impairment in a Rat Model of Depression. ( Dong, L; Hui, J; Jiang, D; Mao, X; Pu, M; Shi, G; Wu, J; Xi, G; Zhang, J; Zhou, X; Zou, J, 2018) |
| " At the end of dosing schedule, neurobehavioral tests were conducted; followed by mechanistic evaluation through biochemical analysis, RTPCR and western blot in serum and hippocampus." | 1.48 | Antidepressant activity of vorinostat is associated with amelioration of oxidative stress and inflammation in a corticosterone-induced chronic stress model in mice. ( Js, IC; Kv, A; Lahkar, M; Madhana, RM; Naidu, VGM; Sinha, S, 2018) |
| "Agmatine is an endogenous neuromodulator that has been shown to have beneficial effects in the central nervous system, including antidepressant-like effects in animals." | 1.48 | Antidepressant and pro-neurogenic effects of agmatine in a mouse model of stress induced by chronic exposure to corticosterone. ( Azevedo, DP; Brocardo, PS; Fraga, DB; Gil-Mohapel, J; Melleu, FF; Neis, VB; Olescowicz, G; Rodrigues, ALS; Rosa, PB, 2018) |
| "Depression is commonly associated with hypothalamic-pituitary adrenal (HPA) axis dysfunction that primarily manifests as aberrant glucocorticoid secretion." | 1.48 | Differential effects of imipramine and CORT118335 (Glucocorticoid receptor modulator/mineralocorticoid receptor antagonist) on brain-endocrine stress responses and depression-like behavior in female rats. ( Balmer, NJ; Caldwell, JL; Estrada, CM; Ghisays, V; Nguyen, ET; Solomon, MB; Streicher, J, 2018) |
| "Comorbid depression was induced by five inescapable foot-shocks (2mA, 2ms duration) at 10s intervals on days 1, 5, 7, and 10." | 1.46 | Metformin and ascorbic acid combination therapy ameliorates type 2 diabetes mellitus and comorbid depression in rats. ( Kumar, M; Nayak, PK; Shivavedi, N; Tej, GNVC, 2017) |
| " This study aimed to investigate the effects of mirtazapine (MIRT) alone and combined with alpha-lipoic acid (ALA) against corticosterone (CORT) induced behavioral and oxidative alterations." | 1.46 | Brain antioxidant effect of mirtazapine and reversal of sedation by its combination with alpha-lipoic acid in a model of depression induced by corticosterone. ( de Oliveira, AA; de Sousa, CNS; de Sousa, LC; Honório Júnior, JER; Macedo, D; Maes, M; Medeiros, IDS; Oliveira, TQ; Patrocínio, CFV; Vasconcelos, GS; Vasconcelos, SMM, 2017) |
| " First, we demonstrated that chronic administration of live PS128 showed no adverse effects on physical health." | 1.43 | Alteration of behavior and monoamine levels attributable to Lactobacillus plantarum PS128 in germ-free mice. ( Chou, GT; Chuang, HL; Huang, YT; Liu, WH; Tsai, YC; Wang, S; Wu, CC, 2016) |
| " Interestingly, C-K showed antidepressant-like activities similar to that of Rb3, and Rg3 displayed antidepressant-like effects at lower dosage and faster time, indicating it has better effects than Rb3, whereas Rh2 and PPD failed to show any effect." | 1.43 | Antidepressant-like effects of ginsenosides: A comparison of ginsenoside Rb3 and its four deglycosylated derivatives, Rg3, Rh2, compound K, and 20(S)-protopanaxadiol in mice models of despair. ( Li, Z; Lou, C; Yang, H; Zhang, H; Zhong, Z; Zhou, Z, 2016) |
| "Sulforaphane (SFN) is a natural compound with antioxidative, anti-inflammatory and neuroprotective activities." | 1.43 | Sulforaphane produces antidepressant- and anxiolytic-like effects in adult mice. ( Gao, Q; Gao, Y; Liang, Y; Ma, Y; Shi, H; Wang, X; Wu, S; Xi, Y; Zhao, P, 2016) |
| "Depression is a common psychopathological disorders." | 1.43 | Zinc and imipramine reverse the depression-like behavior in mice induced by chronic restraint stress. ( Ding, Q; Huang, J; Li, H; Mo, F; Shen, H; Shen, Z; Tian, X; Wang, X, 2016) |
| " Furthermore, acute treatment of NPFFR2 agonists in wild-type (WT) mice enhanced the activity of the HPA axis, and chronic administration resulted in depressive and anxiety-like behaviors." | 1.43 | Chronic activation of NPFFR2 stimulates the stress-related depressive behaviors through HPA axis modulation. ( Chang, CC; Chen, JC; Chen, TC; Day, YJ; Huang, GJ; Lin, YT; Liu, TY; Yang, CY; Yu, YL, 2016) |
| "Anhedonia was evaluated using the sucrose preference test (SPT), and behavioural despair was evaluated using the forced swim test (FST) and tail suspension test (TST)." | 1.42 | Depressive-like behaviours and decreased dendritic branching in the medial prefrontal cortex of mice with tumors: A novel validated model of cancer-induced depression. ( Frey, BN; Nashed, MG; Seidlitz, EP; Singh, G, 2015) |
| "Post-traumatic stress disorder (PTSD) is a condition which can develop from exposure to a severe traumatic event such as those occurring during wars or natural disasters." | 1.40 | Moderate treadmill exercise rescues anxiety and depression-like behavior as well as memory impairment in a rat model of posttraumatic stress disorder. ( Alkadhi, K; Allam, F; Dao, AT; Li, L; Patki, G; Salim, S; Solanki, N, 2014) |
| "These results reflect hypersomnia by intrusion of NREM sleep during the active period as well as a decrease in sleep/wake continuity." | 1.40 | NREM sleep hypersomnia and reduced sleep/wake continuity in a neuroendocrine mouse model of anxiety/depression based on chronic corticosterone administration. ( Adrien, J; David, DJ; Escourrou, P; Guiard, BP; Guilloux, JP; Hache, G; Le Dantec, Y, 2014) |
| "Treatment with baicalin (10, 20, 40 mg/kg) prevented these abnormalities induced by CMS." | 1.39 | Chronic treatment with baicalin prevents the chronic mild stress-induced depressive-like behavior: involving the inhibition of cyclooxygenase-2 in rat brain. ( Jiao, S; Li, J; Li, YC; Shen, JD; Wang, R; Yi, LT, 2013) |
| "Pneumococcal meningitis is a severe infectious disease of the central nervous system, associated with acute inflammation and might cause damage to the host, such as deafness, blindness, seizure, and learning deficits." | 1.38 | Imipramine reverses depressive-like parameters in pneumococcal meningitis survivor rats. ( Barichello, T; Cipriano, AL; Comim, CM; Costa, CS; Generoso, JS; Milioli, G; Moreira, AP; Quevedo, J; Teixeira, AL; Vilela, MC, 2012) |
| " Pharmacokinetic studies performed on these groups indicated that urinary free cortisol and cortisol-to-cortisone ratios can be treated as biomarkers of stress and depressive disorders." | 1.37 | Simultaneous determination of urinary cortisol, cortisone and corticosterone in parachutists, depressed patients and healthy controls in view of biomedical and pharmacokinetic studies. ( Bączek, T; Konieczna, L; Kowalski, P; Olędzka, I; Plenis, A, 2011) |
| "Rosiglitazone treatment (6 or 12 mg/kg, orally) significantly reduced plasma corticosterone levels in rats." | 1.35 | Antidepressant-like effects of rosiglitazone, a PPARγ agonist, in the rat forced swim and mouse tail suspension tests. ( Al-Rasheed, NM; Eissa Ahmed, AA, 2009) |
| "Corticosterone levels were elevated in CMS-treated animals relative to the singly housed control groups, but exposure to a subsequent stressor was not influenced by the stress history." | 1.32 | Evaluation of the effects of chronic mild stressors on hedonic and physiological responses: sex and strain compared. ( Baker, SL; Barbagallo, LS; Bielajew, C; Kentner, AC; Konkle, AT; Merali, Z, 2003) |
| "In corticosterone-treated rats, neurogenesis was decreased by 75%." | 1.31 | Electroconvulsive seizures increase hippocampal neurogenesis after chronic corticosterone treatment. ( Bengzon, J; Ekdahl, CT; Hellsten, J; Mohapel, P; Tingström, A; Wennström, M, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (9.86) | 18.7374 |
| 1990's | 8 (3.76) | 18.2507 |
| 2000's | 33 (15.49) | 29.6817 |
| 2010's | 145 (68.08) | 24.3611 |
| 2020's | 6 (2.82) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, JE | 1 |
| Park, SY | 1 |
| Han, PL | 4 |
| Shuster, AL | 1 |
| Rocha, FE | 1 |
| Wayszceyk, S | 1 |
| de Lima, DD | 1 |
| Barauna, SC | 1 |
| Lopes, BG | 1 |
| Alberton, MD | 1 |
| Magro, DDD | 1 |
| Lee, EH | 1 |
| Park, JY | 3 |
| Kwon, HJ | 1 |
| Lovelock, DF | 1 |
| Deak, T | 1 |
| Jiang, N | 1 |
| Lv, JW | 1 |
| Wang, HX | 1 |
| Lu, C | 1 |
| Wang, Q | 1 |
| Xia, TJ | 1 |
| Bao, Y | 1 |
| Li, SS | 1 |
| Liu, XM | 1 |
| Schelder-Marzzani, SH | 1 |
| Dias, P | 1 |
| Freiberger, V | 1 |
| Ventura, L | 1 |
| Silva, BB | 1 |
| Dutra, ML | 1 |
| Bobinski, F | 1 |
| Schlindwein, AD | 1 |
| Cassol, OJ | 1 |
| Comim, CM | 2 |
| Kim, A | 1 |
| Jung, HG | 1 |
| Kim, YE | 1 |
| Kim, SC | 1 |
| Lee, SG | 1 |
| Hwang, EM | 1 |
| Juneja, A | 1 |
| Barenboim, L | 1 |
| Jacobson, L | 3 |
| Bullich, S | 1 |
| Delcourte, S | 1 |
| Haddjeri, N | 1 |
| Guiard, BP | 2 |
| Dávila-Hernández, A | 1 |
| González-González, R | 1 |
| Guzmán-Velázquez, S | 1 |
| Hernández Hernández, OT | 1 |
| Zamudio, SR | 1 |
| Martínez-Mota, L | 1 |
| Lebedeva, KA | 1 |
| Caruncho, HJ | 2 |
| Kalynchuk, LE | 3 |
| Egeland, M | 1 |
| Guinaudie, C | 1 |
| Du Preez, A | 1 |
| Musaelyan, K | 1 |
| Zunszain, PA | 1 |
| Fernandes, C | 1 |
| Pariante, CM | 1 |
| Thuret, S | 1 |
| Oliveira, TQ | 1 |
| de Sousa, CNS | 1 |
| Vasconcelos, GS | 2 |
| de Sousa, LC | 1 |
| de Oliveira, AA | 1 |
| Patrocínio, CFV | 1 |
| Medeiros, IDS | 1 |
| Honório Júnior, JER | 1 |
| Maes, M | 2 |
| Macedo, D | 2 |
| Vasconcelos, SMM | 1 |
| Qiuxia, Z | 1 |
| Xinlong, M | 1 |
| Yilong, Y | 1 |
| Hui, Z | 1 |
| Yali, W | 1 |
| Xiaoquan, Y | 1 |
| Lei, W | 1 |
| Jiahui, C | 1 |
| Haiyan, Z | 1 |
| Lui, E | 1 |
| Salim, M | 1 |
| Chahal, M | 1 |
| Puri, N | 1 |
| Marandi, E | 1 |
| Quadrilatero, J | 1 |
| Satvat, E | 1 |
| Thakare, VN | 1 |
| Aswar, MK | 1 |
| Kulkarni, YP | 1 |
| Patil, RR | 1 |
| Patel, BM | 1 |
| Abuelezz, SA | 1 |
| Hendawy, N | 1 |
| Wang, SS | 1 |
| Mu, RH | 1 |
| Li, CF | 1 |
| Dong, SQ | 1 |
| Geng, D | 1 |
| Liu, Q | 1 |
| Yi, LT | 2 |
| Shivavedi, N | 1 |
| Kumar, M | 1 |
| Tej, GNVC | 1 |
| Nayak, PK | 1 |
| Olescowicz, G | 1 |
| Neis, VB | 1 |
| Fraga, DB | 1 |
| Rosa, PB | 1 |
| Azevedo, DP | 1 |
| Melleu, FF | 1 |
| Brocardo, PS | 1 |
| Gil-Mohapel, J | 1 |
| Rodrigues, ALS | 1 |
| Brkic, Z | 1 |
| Francija, E | 1 |
| Petrovic, Z | 1 |
| Franic, D | 1 |
| Lukic, I | 1 |
| Mitic, M | 1 |
| Adzic, M | 1 |
| Nguyen, ET | 1 |
| Caldwell, JL | 1 |
| Streicher, J | 1 |
| Ghisays, V | 1 |
| Balmer, NJ | 1 |
| Estrada, CM | 1 |
| Solomon, MB | 1 |
| Iñiguez, SD | 2 |
| Flores-Ramirez, FJ | 1 |
| Riggs, LM | 2 |
| Alipio, JB | 1 |
| Garcia-Carachure, I | 1 |
| Hernandez, MA | 1 |
| Sanchez, DO | 1 |
| Lobo, MK | 1 |
| Serrano, PA | 1 |
| Braren, SH | 1 |
| Castillo, SA | 1 |
| Han, M | 1 |
| Ban, JJ | 1 |
| Bae, JS | 1 |
| Shin, CY | 1 |
| Lee, DH | 1 |
| Chung, JH | 1 |
| Hooper, A | 1 |
| Paracha, R | 1 |
| Maguire, J | 1 |
| Xie, X | 1 |
| Shen, Q | 2 |
| Ma, L | 1 |
| Chen, Y | 1 |
| Zhao, B | 1 |
| Fu, Z | 1 |
| Ayuob, NN | 1 |
| El Wahab, MGA | 1 |
| Ali, SS | 1 |
| Abdel-Tawab, HS | 1 |
| Zhao, Y | 1 |
| Lin, Z | 1 |
| Chen, L | 1 |
| Ouyang, L | 1 |
| Gu, L | 1 |
| Chen, F | 1 |
| Zhang, Q | 1 |
| Takai, Y | 1 |
| Kawai, M | 1 |
| Ogo, T | 1 |
| Ichinose, T | 1 |
| Furuya, S | 1 |
| Takaki, N | 1 |
| Tone, Y | 1 |
| Udo, H | 1 |
| Furuse, M | 2 |
| Yasuo, S | 1 |
| Kv, A | 1 |
| Madhana, RM | 1 |
| Js, IC | 1 |
| Lahkar, M | 1 |
| Sinha, S | 1 |
| Naidu, VGM | 1 |
| Wang, JM | 1 |
| Pei, LX | 1 |
| Zhang, YY | 1 |
| Cheng, YX | 1 |
| Niu, CL | 1 |
| Cui, Y | 1 |
| Feng, WS | 1 |
| Wang, GF | 1 |
| Godoy, LD | 1 |
| Umeoka, EHL | 1 |
| Ribeiro, DE | 1 |
| Santos, VR | 1 |
| Antunes-Rodrigues, J | 1 |
| Joca, SRL | 1 |
| Garcia-Cairasco, N | 1 |
| Bogi, E | 1 |
| Belovicová, K | 1 |
| Ujhazy, E | 1 |
| Mach, M | 1 |
| Koprdova, R | 1 |
| Zilava, L | 1 |
| Garafová, A | 1 |
| Jezova, D | 2 |
| Dubovicky, M | 1 |
| Zhang, YP | 1 |
| Wang, HY | 1 |
| Zhang, C | 2 |
| Liu, BP | 1 |
| Peng, ZL | 1 |
| Li, YY | 1 |
| Liu, FM | 1 |
| Song, C | 4 |
| Kott, JM | 2 |
| Mooney-Leber, SM | 2 |
| Li, J | 3 |
| Brummelte, S | 2 |
| Hui, J | 1 |
| Zhang, J | 2 |
| Pu, M | 1 |
| Zhou, X | 1 |
| Dong, L | 1 |
| Mao, X | 1 |
| Shi, G | 1 |
| Zou, J | 1 |
| Wu, J | 1 |
| Jiang, D | 1 |
| Xi, G | 1 |
| Weina, H | 1 |
| Yuhu, N | 1 |
| Christian, H | 1 |
| Birong, L | 1 |
| Feiyu, S | 1 |
| Le, W | 1 |
| He, XY | 1 |
| Chen, JL | 1 |
| Xiang, H | 1 |
| Gao, Y | 2 |
| Tian, JS | 1 |
| Qin, XM | 1 |
| Du, GH | 1 |
| Houwing, DJ | 1 |
| Ramsteijn, AS | 1 |
| Riemersma, IW | 1 |
| Olivier, JDA | 1 |
| Abd El-Fattah, AA | 1 |
| Fahim, AT | 1 |
| Sadik, NAH | 1 |
| Ali, BM | 1 |
| Huang, X | 1 |
| Xiaokaiti, Y | 1 |
| Yang, J | 1 |
| Pan, J | 1 |
| Li, Z | 2 |
| Luria, V | 1 |
| Li, Y | 1 |
| Song, G | 1 |
| Zhu, X | 1 |
| Zhang, HT | 1 |
| O'Donnell, JM | 1 |
| Xu, Y | 2 |
| Ding, H | 1 |
| Cui, XY | 1 |
| Cui, SY | 1 |
| Ye, H | 1 |
| Hu, X | 1 |
| Zhao, HL | 1 |
| Liu, YT | 1 |
| Zhang, YH | 1 |
| Ishikawa, T | 1 |
| Okano, M | 1 |
| Minami, A | 1 |
| Tsunekawa, H | 1 |
| Satoyoshi, H | 1 |
| Tsukamoto, Y | 1 |
| Takahata, K | 1 |
| Muraoka, S | 1 |
| Lam, VYY | 1 |
| Raineki, C | 1 |
| Wang, LY | 1 |
| Chiu, M | 1 |
| Lee, G | 1 |
| Ellis, L | 1 |
| Yu, W | 1 |
| Weinberg, J | 1 |
| Kumar, A | 2 |
| Dogra, S | 1 |
| Sona, C | 1 |
| Umrao, D | 1 |
| Rashid, M | 1 |
| Singh, SK | 1 |
| Wahajuddin, M | 1 |
| Yadav, PN | 1 |
| Bekhbat, M | 1 |
| Howell, PA | 1 |
| Rowson, SA | 1 |
| Kelly, SD | 1 |
| Tansey, MG | 1 |
| Neigh, GN | 1 |
| Seo, MK | 1 |
| Lee, JG | 1 |
| Park, SW | 1 |
| Kinlein, SA | 1 |
| Phillips, DJ | 1 |
| Keller, CR | 1 |
| Karatsoreos, IN | 1 |
| Liu, W | 4 |
| Liu, J | 2 |
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| Wang, ZG | 1 |
| Guo, L | 1 |
| Fei, J | 1 |
| Steimer, T | 1 |
| Python, A | 1 |
| Schulz, PE | 1 |
| Aubry, JM | 1 |
| Silva, R | 1 |
| Mesquita, AR | 1 |
| Bessa, J | 1 |
| Sousa, JC | 1 |
| Sotiropoulos, I | 1 |
| Leão, P | 1 |
| Almeida, OF | 1 |
| Sousa, N | 1 |
| Urigüen, L | 1 |
| Arteta, D | 1 |
| Díez-Alarcia, R | 1 |
| Ferrer-Alcón, M | 1 |
| Díaz, A | 1 |
| Pazos, A | 1 |
| Meana, JJ | 1 |
| Popa, D | 1 |
| Léna, C | 1 |
| Alexandre, C | 1 |
| Jama, A | 1 |
| Cecchi, M | 1 |
| Calvo, N | 1 |
| Watson, SJ | 1 |
| Akil, H | 1 |
| Müller, OA | 3 |
| Doerr, HG | 2 |
| Sippell, WG | 3 |
| Stalla, GK | 3 |
| Gerken, A | 5 |
| Steiger, A | 1 |
| Boll, E | 1 |
| Benkert, O | 1 |
| Richardson, JS | 1 |
| Wilens, TE | 3 |
| Arana, GW | 3 |
| Baldessarini, RJ | 2 |
| Cremens, C | 1 |
| Haack, D | 1 |
| Vecsei, P | 2 |
| Ritchie, JC | 2 |
| Carroll, BJ | 2 |
| Katz, RJ | 2 |
| Sibel, M | 2 |
| Winter, K | 1 |
| Dörr, HG | 1 |
| Tateishi, N | 1 |
| Kelly, JP | 2 |
| Leonard, BE | 3 |
| Báez, M | 1 |
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| Biagini, G | 1 |
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| Carani, C | 1 |
| Marrama, P | 1 |
| Gustafsson, JA | 1 |
| Lahmame, A | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Probiotic Bacteria on Brain Structure and Function and on Psychological Variables[NCT03478527] | 59 participants (Actual) | Interventional | 2018-01-08 | Completed | |||
| Pioglitazone as an Adjunct for Moderate to Severe Depressive Disorder[NCT01109030] | Phase 2/Phase 3 | 50 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for corticosterone and Depressive Disorder
| Article | Year |
|---|---|
Behavioral and neurobiological consequences of prolonged glucocorticoid exposure in rats: relevance to depression.
Topics: Adult; Animals; Anxiety; Behavior, Animal; Brain; Cognition; Corticosterone; Depressive Disorder; Di | 2010 |
Aldosterone increases earlier than corticosterone in new animal models of depression: is this an early marker?
Topics: Aldosterone; Animals; Biomarkers; Corticosterone; Depressive Disorder; Disease Models, Animal; Femal | 2012 |
The effect of thymectomy and IL-1 on memory: implications for the relationship between immunity and depression.
Topics: Animals; Corticosterone; Cytokines; Depressive Disorder; Disease Models, Animal; Dopamine; Hormone A | 2002 |
The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies.
Topics: Adrenocorticotropic Hormone; Adult; Animals; Anxiety Disorders; Anxiety, Separation; Brain; Child; C | 2001 |
The dexamethasone suppression test and depression. Approaches to the use of a laboratory test in psychiatry.
Topics: Adrenocorticotropic Hormone; Antidepressive Agents; Corticosterone; Corticotropin-Releasing Hormone; | 1988 |
1 trial available for corticosterone and Depressive Disorder
| Article | Year |
|---|---|
Increased diurnal plasma concentrations of cortisone in depressed patients.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Circadian Rhythm; Corticosterone; Cortisone; Depressive Disor | 2000 |
207 other studies available for corticosterone and Depressive Disorder
| Article | Year |
|---|---|
Aging-Dependent Downregulation of SUV39H1 Histone Methyltransferase Increases Susceptibility to Stress-Induced Depressive Behavior.
Topics: Aging; Animals; Behavior, Animal; Cell Line; Corticosterone; Depressive Disorder; Down-Regulation; H | 2021 |
Protective effect of Myrcia pubipetala Miq. against the alterations in oxidative stress parameters in an animal model of depression induced by corticosterone.
Topics: Animals; Antioxidants; Catalase; Cerebral Cortex; Corticosterone; Depressive Disorder; Disease Model | 2022 |
Repeated exposure with short-term behavioral stress resolves pre-existing stress-induced depressive-like behavior in mice.
Topics: Aggression; Animals; Brain; Corticosterone; Depressive Disorder; Female; Gene Expression Profiling; | 2021 |
Acute stress imposed during adolescence yields heightened anxiety in Sprague Dawley rats that persists into adulthood: Sex differences and potential involvement of the Medial Amygdala.
Topics: Animals; Anxiety; Anxiety Disorders; Brain; Corticomedial Nuclear Complex; Corticosterone; Corticotr | 2019 |
Dammarane sapogenins alleviates depression-like behaviours induced by chronic social defeat stress in mice through the promotion of the BDNF signalling pathway and neurogenesis in the hippocampus.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Corticosterone; Dammaranes; Depre | 2019 |
Neonatal Immune Activation May Provoke Long-term Depressive Attributes.
Topics: Animals; Animals, Newborn; Corticosterone; Depression; Depressive Disorder; Disease Models, Animal; | 2019 |
The Knockdown of TREK-1 in Hippocampal Neurons Attenuate Lipopolysaccharide-Induced Depressive-Like Behavior in Mice.
Topics: Animals; Behavior, Animal; Corticosterone; Cytokines; Dentate Gyrus; Dependovirus; Depressive Disord | 2019 |
Selective effects of dorsal raphé nucleus glucocorticoid receptor deletion on depression-like behavior in female C57BL/6J mice.
Topics: Animals; Behavior, Animal; Corticosterone; Depression; Depressive Disorder; Dorsal Raphe Nucleus; Fe | 2020 |
Learned Immobility Produces Enduring Impairment of the HPA Axis Reactivity in Mice without Replicating the Broad Spectrum of Depressive-Like Phenotype.
Topics: Animals; Antidepressive Agents; Anxiety; Anxiety Disorders; Behavior, Animal; Corticosterone; Depres | 2021 |
Antidepressant-like effects of acupuncture via modulation of corticosterone, sex hormones, and hippocampal BDNF expression in male rats.
Topics: Acupuncture Therapy; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corticosterone; D | 2021 |
Cyclical corticosterone administration sensitizes depression-like behavior in rats.
Topics: Animals; Behavior, Animal; Corticosterone; Depressive Disorder; Disease Models, Animal; Dose-Respons | 2017 |
Depletion of adult neurogenesis using the chemotherapy drug temozolomide in mice induces behavioural and biological changes relevant to depression.
Topics: Animals; Antineoplastic Agents, Alkylating; Behavior, Animal; Biochemical Phenomena; Brain; Brain Ne | 2017 |
Brain antioxidant effect of mirtazapine and reversal of sedation by its combination with alpha-lipoic acid in a model of depression induced by corticosterone.
Topics: Animals; Antidepressive Agents, Tricyclic; Antioxidants; Brain; Brain-Derived Neurotrophic Factor; C | 2017 |
JIEYUANSHEN DECOCTION EXERTS ANTIDEPRESSANT EFFECTS ON DEPRESSIVE RAT MODEL VIA REGULATING HPA AXIS AND THE LEVEL OF AMINO ACIDS NEUROTRANSMITTER.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Chronic Disease; Corticosterone; Cortic | 2017 |
Chronic corticosterone-induced impaired cognitive flexibility is not due to suppressed adult hippocampal neurogenesis.
Topics: Animals; Bromodeoxyuridine; Cell Survival; Cognition; Corticosterone; Depressive Disorder; Disease M | 2017 |
Silymarin ameliorates experimentally induced depressive like behavior in rats: Involvement of hippocampal BDNF signaling, inflammatory cytokines and oxidative stress response.
Topics: Animals; Antidepressive Agents; Antioxidants; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Co | 2017 |
Insights into the potential antidepressant mechanisms of cilostazol in chronically restraint rats: impact on the Nrf2 pathway.
Topics: Animals; Antidepressive Agents; Antioxidants; Cilostazol; Corticosterone; Depression; Depressive Dis | 2018 |
microRNA-124 targets glucocorticoid receptor and is involved in depression-like behaviors.
Topics: Animals; Antagomirs; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Corticosterone; Depre | 2017 |
Metformin and ascorbic acid combination therapy ameliorates type 2 diabetes mellitus and comorbid depression in rats.
Topics: Animals; Ascorbic Acid; Biogenic Monoamines; Blood Glucose; Comorbidity; Corticosterone; Cytokines; | 2017 |
Antidepressant and pro-neurogenic effects of agmatine in a mouse model of stress induced by chronic exposure to corticosterone.
Topics: Agmatine; Anhedonia; Animals; Antidepressive Agents; Cell Proliferation; Corticosterone; Depressive | 2018 |
Distinct modifications of hippocampal glucocorticoid receptor phosphorylation and FKBPs by lipopolysaccharide in depressive female and male rats.
Topics: Animals; Brain-Derived Neurotrophic Factor; Corticosterone; Depression; Depressive Disorder; Female; | 2017 |
Differential effects of imipramine and CORT118335 (Glucocorticoid receptor modulator/mineralocorticoid receptor antagonist) on brain-endocrine stress responses and depression-like behavior in female rats.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behav | 2018 |
Vicarious Social Defeat Stress Induces Depression-Related Outcomes in Female Mice.
Topics: Animals; Antidepressive Agents; Avoidance Learning; Body Weight; Chlordiazepoxide; Corticosterone; D | 2018 |
UV irradiation to mouse skin decreases hippocampal neurogenesis and synaptic protein expression via HPA axis activation.
Topics: Animals; Brain-Derived Neurotrophic Factor; Corticosterone; Depressive Disorder; Disks Large Homolog | 2017 |
Seizure-induced activation of the HPA axis increases seizure frequency and comorbid depression-like behaviors.
Topics: Animals; Corticosterone; Corticotropin-Releasing Hormone; Depression; Depressive Disorder; Hypothala | 2018 |
Chronic corticosterone-induced depression mediates premature aging in rats.
Topics: Aging, Premature; Animals; Anti-Inflammatory Agents; Antioxidants; Chronic Disease; Corticosterone; | 2018 |
Ocimum basilicum improve chronic stress-induced neurodegenerative changes in mice hippocampus.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corticosterone; | 2018 |
Hippocampal astrocyte atrophy in a mouse depression model induced by corticosterone is reversed by fluoxetine instead of benzodiazepine diazepam.
Topics: Animals; Antidepressive Agents; Astrocytes; Atrophy; Corticosterone; Depressive Disorder; Diazepam; | 2018 |
Early-life Photoperiod Influences Depression-like Behavior, Prepulse Inhibition of the Acoustic Startle Response, and Hippocampal Astrogenesis in Mice.
Topics: Animals; Animals, Newborn; Astrocytes; Auditory Perception; Bromodeoxyuridine; Corticosterone; Depre | 2018 |
Antidepressant activity of vorinostat is associated with amelioration of oxidative stress and inflammation in a corticosterone-induced chronic stress model in mice.
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents; Antioxidants; Anxiety; Chronic Disease; Co | 2018 |
Ethanol extract of Rehmannia glutinosa exerts antidepressant-like effects on a rat chronic unpredictable mild stress model by involving monoamines and BDNF.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Corticosterone; Depressive Disord | 2018 |
Multimodal early-life stress induces biological changes associated to psychopathologies.
Topics: Animals; Animals, Newborn; Anxiety Disorders; Corticosterone; Depressive Disorder; Female; Hippocamp | 2018 |
Perinatal exposure to venlafaxine leads to lower anxiety and depression-like behavior in the adult rat offspring.
Topics: Adrenal Cortex Hormones; Aldosterone; Animals; Animals, Newborn; Anxiety; Anxiety Disorders; Behavio | 2018 |
Mifepristone attenuates depression-like changes induced by chronic central administration of interleukin-1β in rats.
Topics: Amygdala; Anhedonia; Animals; Antidepressive Agents; Corticosterone; Depressive Disorder; Disease Mo | 2018 |
Elevated stress hormone levels and antidepressant treatment starting before pregnancy affect maternal care and litter characteristics in an animal model of depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; Depression, Postpartum | 2018 |
Modulation of GSK-3β/β-Catenin Signaling Contributes to Learning and Memory Impairment in a Rat Model of Depression.
Topics: Animals; beta Catenin; Cognitive Dysfunction; Corticosterone; Depressive Disorder; Disease Models, A | 2018 |
Liraglutide attenuates the depressive- and anxiety-like behaviour in the corticosterone induced depression model via improving hippocampal neural plasticity.
Topics: Alzheimer Disease; Animals; Antidepressive Agents; Anxiety; Corticosterone; Depression; Depressive D | 2018 |
[Comparative study of the corticosterone and glutamate induced PC12 cells depression model by 1H NMR metabolomics].
Topics: Animals; Antioxidants; Corticosterone; Depression; Depressive Disorder; Fatty Acids; Glutamic Acid; | 2017 |
Maternal separation induces anhedonia in female heterozygous serotonin transporter knockout rats.
Topics: Anhedonia; Animals; Behavior, Animal; Brain; Corticosterone; Depression; Depressive Disorder; Hetero | 2019 |
Resveratrol and dimethyl fumarate ameliorate depression-like behaviour in a rat model of chronic unpredictable mild stress.
Topics: Animals; Antidepressive Agents; Antioxidants; Apoptosis; beta Catenin; Brain-Derived Neurotrophic Fa | 2018 |
Inhibition of phosphodiesterase 2 reverses gp91phox oxidase-mediated depression- and anxiety-like behavior.
Topics: Animals; Antioxidants; Anxiety Disorders; Cell Line; Corticosterone; Cyclic Nucleotide Phosphodieste | 2018 |
Depression-like behaviors induced by chronic corticosterone exposure via drinking water: Time-course analysis.
Topics: Animals; Behavior, Animal; Corticosterone; Depression; Depressive Disorder; Disease Models, Animal; | 2018 |
Selegiline ameliorates depression-like behaviors in rodents and modulates hippocampal dopaminergic transmission and synaptic plasticity.
Topics: Animals; Antidepressive Agents; Corticosterone; Depressive Disorder; Dopamine; Dose-Response Relatio | 2019 |
Role of corticosterone in anxiety- and depressive-like behavior and HPA regulation following prenatal alcohol exposure.
Topics: Animals; Anxiety Disorders; Central Nervous System Depressants; Corticosterone; Depressive Disorder; | 2019 |
Chronic histamine 3 receptor antagonism alleviates depression like conditions in mice via modulation of brain-derived neurotrophic factor and hypothalamus-pituitary adrenal axis.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain; Brain-Derived Neurotrophic Factor; Corticos | 2019 |
Chronic adolescent stress sex-specifically alters central and peripheral neuro-immune reactivity in rats.
Topics: Age Factors; Animals; Anxiety; Anxiety Disorders; Central Nervous System; Corticosterone; Cytokines; | 2019 |
Glucocorticoid receptor deletion from locus coeruleus norepinephrine neurons promotes depression-like social withdrawal in female but not male mice.
Topics: Animals; Antidepressive Agents; Brain; Corticosterone; Depression; Depressive Disorder; Dorsal Raphe | 2019 |
Effects of escitalopram and ibuprofen on a depression-like phenotype induced by chronic stress in rats.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Citalopram; Cor | 2019 |
Role of corticosterone in altered neurobehavioral responses to acute stress in a model of compromised hypothalamic-pituitary-adrenal axis function.
Topics: Animals; Anxiety; Anxiety Disorders; Corticosterone; Depression; Depressive Disorder; Disease Models | 2019 |
Possible role of GLP-1 in antidepressant effects of metformin and exercise in CUMS mice.
Topics: Animals; Antidepressive Agents; bcl-2-Associated X Protein; Corticosterone; Depression; Depressive D | 2019 |
Antidepressive Effects of Taraxacum Officinale in a Mouse Model of Depression Are Due to Inhibition of Corticosterone Levels and Modulation of Mitogen-Activated Protein Kinase Phosphatase-1 (Mkp-1) and Brain-Derived Neurotrophic Factor (Bdnf) Expression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corticosterone; | 2019 |
Antidepressant-like activities of live and heat-killed Lactobacillus paracasei PS23 in chronic corticosterone-treated mice and possible mechanisms.
Topics: Animals; Antidepressive Agents; Anxiety; Anxiety Disorders; Behavior, Animal; Brain; Corticosterone; | 2019 |
DNA methylation of the Tacr2 gene in a CUMS model of depression.
Topics: Animals; Body Weight; Corticosterone; Corticotropin-Releasing Hormone; Depression; Depressive Disord | 2019 |
PINK1 deficiency is associated with increased deficits of adult hippocampal neurogenesis and lowers the threshold for stress-induced depression in mice.
Topics: Animals; Anxiety; Anxiety Disorders; Behavior, Animal; Cell Differentiation; Cell Proliferation; Cor | 2019 |
Ketamine improved depressive-like behaviors via hippocampal glucocorticoid receptor in chronic stress induced- susceptible mice.
Topics: Animals; Anxiety; Corticosterone; Depression; Depressive Disorder; Disease Models, Animal; Gene Expr | 2019 |
Developmental outcomes after gestational antidepressant treatment with sertraline and its discontinuation in an animal model of maternal depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; Depressive Disorder; D | 2019 |
Decreased stress-induced depression-like behavior in lactating rats is associated with changes in the hypothalamic-pituitary-adrenal axis, brain monoamines, and brain amino acid metabolism.
Topics: Adrenocorticotropic Hormone; Amino Acids; Animals; Brain; Catecholamines; Corticosterone; Depression | 2019 |
Faecalibacterium prausnitzii (ATCC 27766) has preventive and therapeutic effects on chronic unpredictable mild stress-induced depression-like and anxiety-like behavior in rats.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Behavior, Animal; Bone Density; Brain; Bra | 2019 |
Effects of corticosterone on the expression of mature brain-derived neurotrophic factor (mBDNF) and proBDNF in the hippocampal dentate gyrus.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Corticosterone; Dentate Gyrus; De | 2019 |
Sustained rescue of prefrontal circuit dysfunction by antidepressant-induced spine formation.
Topics: Animals; Antidepressive Agents; Corticosterone; Dendritic Spines; Depressive Disorder; Disease Model | 2019 |
Antidepressive effect of sodium valproate involving suppression of corticotropin-releasing factor expression and elevation of BDNF expression in rats exposed to chronic unpredicted stress.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Corticosterone; Corticotropin-Rel | 2014 |
Rapid anxiolytic effects of a 5-HT₄ receptor agonist are mediated by a neurogenesis-independent mechanism.
Topics: Aniline Compounds; Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Anxiety; | 2014 |
Deficiency of FK506-binding protein (FKBP) 51 alters sleep architecture and recovery sleep responses to stress in mice.
Topics: Animals; Corticosterone; Depressive Disorder; Humans; Hypothalamo-Hypophyseal System; Male; Mice; Mi | 2014 |
Depression-like behaviors in mice subjected to co-treatment of high-fat diet and corticosterone are ameliorated by AICAR and exercise.
Topics: Aminoimidazole Carboxamide; Animals; Corticosterone; Depression; Depressive Disorder; Diet, High-Fat | 2014 |
Increased depression-like behaviors with dysfunctions in the stress axis and the reward center by free access to highly palatable food.
Topics: Animal Feed; Animals; Cacao; Corticosterone; Depressive Disorder; Diet; Eating; Exploratory Behavior | 2014 |
Aquaporin-4 knockout exacerbates corticosterone-induced depression by inhibiting astrocyte function and hippocampal neurogenesis.
Topics: Animals; Aquaporin 4; Astrocytes; Cell Death; Cells, Cultured; Corticosterone; Depressive Disorder; | 2014 |
Inhibition of stress-induced hepatic tryptophan 2,3-dioxygenase exhibits antidepressant activity in an animal model of depressive behaviour.
Topics: Allopurinol; Animals; Antidepressive Agents; Cerebral Cortex; Chronic Disease; Corticosterone; Depre | 2014 |
Pitx3 deficient mice as a genetic animal model of co-morbid depressive disorder and parkinsonism.
Topics: Anhedonia; Animals; Antidepressive Agents; Brain; Comorbidity; Corticosterone; Depressive Disorder; | 2014 |
Panax quinquefolium involves nitric oxide pathway in olfactory bulbectomy rat model.
Topics: Anhedonia; Animals; Arginine; Brain; Corticosterone; Depressive Disorder; Disease Models, Animal; Do | 2014 |
Evidence supporting the match/mismatch hypothesis of psychiatric disorders.
Topics: Adaptation, Psychological; Adrenal Glands; Amino Acid Transport Systems, Neutral; Animals; Anxiety D | 2014 |
Estrogen receptor β and oxytocin interact to modulate anxiety-like behavior and neuroendocrine stress reactivity in adult male and female rats.
Topics: Adrenocorticotropic Hormone; Animals; Anxiety; Central Nervous System Agents; Corticosterone; Depres | 2014 |
Moderate treadmill exercise rescues anxiety and depression-like behavior as well as memory impairment in a rat model of posttraumatic stress disorder.
Topics: Anhedonia; Animals; Anxiety Disorders; Corticosterone; Depressive Disorder; Disease Models, Animal; | 2014 |
Social defeat stress induces a depression-like phenotype in adolescent male c57BL/6 mice.
Topics: Aging; Animals; Anxiety; Corticosterone; Depression; Depressive Disorder; Dietary Carbohydrates; Dom | 2014 |
Monosodium glutamate, a food additive, induces depressive-like and anxiogenic-like behaviors in young rats.
Topics: Adrenocorticotropic Hormone; Animals; Animals, Newborn; Anxiety Disorders; Behavior, Animal; Cerebra | 2014 |
Sustained running in rats administered corticosterone prevents the development of depressive behaviors and enhances hippocampal neurogenesis and synaptic plasticity without increasing neurotrophic factor levels.
Topics: Animals; Anti-Inflammatory Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corticostero | 2014 |
Increased number of orexin/hypocretin neurons with high and prolonged external stress-induced depression.
Topics: Animals; Body Weight; Cell Count; Circadian Rhythm; Corticosterone; Depressive Disorder; Disease Mod | 2014 |
Effects of electroconvulsive seizures on depression-related behavior, memory and neurochemical changes in Wistar and Wistar-Kyoto rats.
Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Corticosterone; Corticotropin-Releasing Hormone; | 2014 |
Pycnogenol ameliorates depression-like behavior in repeated corticosterone-induced depression mice model.
Topics: Animals; Antioxidants; Corticosterone; Depression; Depressive Disorder; Disease Models, Animal; Flav | 2014 |
NREM sleep hypersomnia and reduced sleep/wake continuity in a neuroendocrine mouse model of anxiety/depression based on chronic corticosterone administration.
Topics: Animals; Anxiety Disorders; Brain; Corticosterone; Darkness; Depressive Disorder; Disease Models, An | 2014 |
Repeated restraint stress-induced atrophy of glutamatergic pyramidal neurons and decreases in glutamatergic efflux in the rat amygdala are prevented by the antidepressant agomelatine.
Topics: Acetamides; Animals; Antidepressive Agents; Atrophy; Basolateral Nuclear Complex; Corticosterone; De | 2015 |
Elevated brain glucose and glycogen concentrations in an animal model of depression.
Topics: Animals; Brain; Corticosterone; Depressive Disorder; Disease Models, Animal; Female; Glucose; Glucos | 2014 |
Behavioral effects of nicotinic antagonist mecamylamine in a rat model of depression: prefrontal cortex level of BDNF protein and monoaminergic neurotransmitters.
Topics: Animals; Behavior, Animal; Body Weight; Brain-Derived Neurotrophic Factor; Corticosterone; Depressiv | 2015 |
WY14643 produces anti-depressant-like effects in mice via the BDNF signaling pathway.
Topics: Animals; Brain-Derived Neurotrophic Factor; Corticosterone; Depression; Depressive Disorder; Hindlim | 2015 |
Increased antidepressant sensitivity after prefrontal cortex glucocorticoid receptor gene deletion in mice.
Topics: Animals; Antidepressive Agents; Corticosterone; Depressive Disorder; Disease Models, Animal; Gene Kn | 2015 |
Antidepressant effects of abscisic acid mediated by the downregulation of corticotrophin-releasing hormone gene expression in rats.
Topics: Abscisic Acid; Animals; Antidepressive Agents; Cerebral Cortex; Corticosterone; Corticotropin-Releas | 2014 |
Chronic unpredictable mild stress decreases BDNF and NGF levels and Na(+),K(+)-ATPase activity in the hippocampus and prefrontal cortex of mice: antidepressant effect of chrysin.
Topics: Animals; Antidepressive Agents; Antioxidants; Brain-Derived Neurotrophic Factor; Catalase; Chronic D | 2015 |
NLRP3 Inflammasome Mediates Chronic Mild Stress-Induced Depression in Mice via Neuroinflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Carrier Proteins; Caspase 1 | 2015 |
Melancholic-Like behaviors and circadian neurobiological abnormalities in melatonin MT1 receptor knockout mice.
Topics: Animals; Antidepressive Agents, Tricyclic; Chronobiology Disorders; Circadian Rhythm; Corticosterone | 2015 |
CRTH2, a prostaglandin D2 receptor, mediates depression-related behavior in mice.
Topics: Animals; Brain; Carbazoles; Central Nervous System Agents; Chronic Disease; Corticosterone; Cyclooxy | 2015 |
Antidepressant-like effect of geniposide on chronic unpredictable mild stress-induced depressive rats by regulating the hypothalamus-pituitary-adrenal axis.
Topics: Animals; Antidepressive Agents; Chronic Disease; Corticosterone; Corticotropin-Releasing Hormone; De | 2015 |
The Female Encounter Test: A Novel Method for Evaluating Reward-Seeking Behavior or Motivation in Mice.
Topics: Amino Acids; Animals; Antidepressive Agents, Second-Generation; Castration; Choice Behavior; Cortico | 2015 |
Neuropeptide Y administration reverses tricyclic antidepressant treatment-resistant depression induced by ACTH in mice.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents, Tricyclic; Corticosterone; Depressive D | 2015 |
Impaired adrenal medullary function in a mouse model of depression induced by unpredictable chronic stress.
Topics: Adrenal Medulla; Animals; Body Weight; Catecholamine Plasma Membrane Transport Proteins; Catecholami | 2015 |
Depressive-like behaviours and decreased dendritic branching in the medial prefrontal cortex of mice with tumors: A novel validated model of cancer-induced depression.
Topics: Anhedonia; Animals; Antidepressive Agents, Second-Generation; Cell Line, Tumor; Corticosterone; Dend | 2015 |
Evidence for protective effect of lipoic acid and desvenlafaxine on oxidative stress in a model depression in mice.
Topics: Animals; Antidepressive Agents; Antioxidants; Corpus Striatum; Corticosterone; Depressive Disorder; | 2016 |
Antidepressant-like activity and cardioprotective effects of fatty acid amide hydrolase inhibitor URB694 in socially stressed Wistar Kyoto rats.
Topics: Amidohydrolases; Anhedonia; Animals; Antidepressive Agents; Arrhythmias, Cardiac; Biphenyl Compounds | 2015 |
11-β hydroxysteroid type 1 knockout mice display an antidepressant-like phenotype in the forced swim test.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Corticosterone; Depressive Disorder; Glucocort | 2016 |
IL-4 Inhibits IL-1β-Induced Depressive-Like Behavior and Central Neurotransmitter Alterations.
Topics: Animals; Body Temperature; Corticosterone; Depressive Disorder; Dinoprostone; Glial Fibrillary Acidi | 2015 |
Geraniol produces antidepressant-like effects in a chronic unpredictable mild stress mice model.
Topics: Acyclic Monoterpenes; Animals; Antidepressive Agents; Carrier Proteins; Caspase 1; Chronic Disease; | 2015 |
Baicalin decreases SGK1 expression in the hippocampus and reverses depressive-like behaviors induced by corticosterone.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Animals; Antidepressive Agents; Brain-Derived Neurotrop | 2015 |
Depression-like episodes in mice harboring mtDNA deletions in paraventricular thalamus.
Topics: Animals; Comorbidity; Corticosterone; Depressive Disorder; Disease Models, Animal; DNA Polymerase ga | 2016 |
Alteration of behavior and monoamine levels attributable to Lactobacillus plantarum PS128 in germ-free mice.
Topics: Animals; Brain; Corticosterone; Depressive Disorder; Dopamine; Exploratory Behavior; Gastrointestina | 2016 |
Antidepressant-like effects of ginsenosides: A comparison of ginsenoside Rb3 and its four deglycosylated derivatives, Rg3, Rh2, compound K, and 20(S)-protopanaxadiol in mice models of despair.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Brain Chemistry; Corticosterone; Depres | 2016 |
The Role of Nitric Oxide in the Antidepressant Actions of 5-Aminoimidazole-4-Carboxamide-1-β-D-Ribofuranoside in Insulin-Resistant Mice.
Topics: Adenylate Kinase; Aminoimidazole Carboxamide; Animals; Antidepressive Agents; Combined Modality Ther | 2016 |
Chronic corticosterone-mediated dysregulation of microRNA network in prefrontal cortex of rats: relevance to depression pathophysiology.
Topics: Animals; Behavior, Animal; Corticosterone; Depressive Disorder; Disease Models, Animal; Gene Regulat | 2015 |
Evaluation of brain SERT occupancy by resveratrol against MDMA-induced neurobiological and behavioral changes in rats: A 4-[¹⁸F]-ADAM/small-animal PET study.
Topics: Animals; Benzylamines; Brain; Brain Mapping; Corticosterone; Depressive Disorder; Dose-Response Rela | 2016 |
Time-dependent miR-16 serum fluctuations together with reciprocal changes in the expression level of miR-16 in mesocortical circuit contribute to stress resilient phenotype in chronic mild stress - An animal model of depression.
Topics: Anhedonia; Animals; Biomarkers; Chronic Disease; Corticosterone; Depressive Disorder; Dietary Sucros | 2016 |
Long-term characterization of the Flinders Sensitive Line rodent model of human depression: Behavioral and PET evidence of a dysfunctional entorhinal cortex.
Topics: Aging; Animals; Brain Mapping; Corticosterone; Depressive Disorder; Disease Models, Animal; Entorhin | 2016 |
Modulation of the antioxidant nuclear factor (erythroid 2-derived)-like 2 pathway by antidepressants in rats.
Topics: Animals; Antidepressive Agents; Antioxidants; Corticosterone; Depressive Disorder; Disease Models, A | 2016 |
Lithium attenuated the depressant and anxiogenic effect of juvenile social stress through mitigating the negative impact of interlukin-1β and nitric oxide on hypothalamic-pituitary-adrenal axis function.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; Corticosterone; Depressive D | 2016 |
The neurogenic effects of an enriched environment and its protection against the behavioral consequences of chronic mild stress persistent after enrichment cessation in six-month-old female Balb/C mice.
Topics: Anhedonia; Animals; Blood Chemical Analysis; Bromodeoxyuridine; Cell Proliferation; Chronic Disease; | 2016 |
Sulforaphane produces antidepressant- and anxiolytic-like effects in adult mice.
Topics: Adrenocorticotropic Hormone; Animals; Anti-Anxiety Agents; Anti-Inflammatory Agents; Antidepressive | 2016 |
Adolescent chronic stress causes hypothalamo-pituitary-adrenocortical hypo-responsiveness and depression-like behavior in adult female rats.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Corticotropin-Releasing Hormone; Depressive Di | 2016 |
Effect of Inhaling Bergamot Oil on Depression-Related Behaviors in Chronic Stressed Rats.
Topics: Animals; Brain-Derived Neurotrophic Factor; Corticosterone; Depression; Depressive Disorder; Hippoca | 2015 |
5-(4-hydroxy-3-dimethoxybenzylidene)-rhodanine (RD-1)-improved mitochondrial function prevents anxiety- and depressive-like states induced by chronic corticosterone injections in mice.
Topics: Administration, Oral; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; Biolog | 2016 |
Zinc and imipramine reverse the depression-like behavior in mice induced by chronic restraint stress.
Topics: Animals; Brain-Derived Neurotrophic Factor; Corticosterone; CREB-Binding Protein; Depression; Depres | 2016 |
The role of medial prefrontal corticosterone and dopamine in the antidepressant-like effect of exercise.
Topics: Animals; Antidepressive Agents; Corticosterone; Depression; Depressive Disorder; Dopamine; Glucocort | 2016 |
Blood glucose regulation mechanism in depressive disorder animal model during hyperglycemic states.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Blood Glucose; Clonidine; Corticosterone; Depressive | 2016 |
Hypothalamic Proteomic Analysis Reveals Dysregulation of Glutamate Balance and Energy Metabolism in a Mouse Model of Chronic Mild Stress-Induced Depression.
Topics: Animals; Corticosterone; Depression; Depressive Disorder; Disease Models, Animal; Energy Metabolism; | 2016 |
Chronic activation of NPFFR2 stimulates the stress-related depressive behaviors through HPA axis modulation.
Topics: Animals; Antidepressive Agents; Anxiety; Anxiety Disorders; Chronic Disease; Corticosterone; Cortico | 2016 |
Fluoxetine normalizes the effects of prenatal maternal stress on depression- and anxiety-like behaviors in mouse dams and male offspring.
Topics: Animals; Animals, Newborn; Anxiety Disorders; Corticosterone; Depressive Disorder; Disease Models, A | 2016 |
Effects of environmental stress on the depression-like behaviors and the diurnal rhythm of corticosterone and melatonin in male rats.
Topics: Animals; Anxiety; Behavior, Animal; Circadian Rhythm; Corticosterone; Depression; Depressive Disorde | 2016 |
Perinatal programming of depressive-like behavior by inflammation in adult offspring mice whose mothers were fed polluted eels: Gender selective effects.
Topics: Animals; Behavior, Animal; Biomarkers; Brain; Corticosterone; Depression; Depressive Disorder; Femal | 2017 |
Control of stress-induced depressive disorders by So-ochim-tang-gamibang, a Korean herbal medicine.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Caspase 3; Cell | 2017 |
Brief Social Isolation in the Adolescent Wistar-Kyoto Rat Model of Endogenous Depression Alters Corticosterone and Regional Monoamine Concentrations.
Topics: Age Factors; Animals; Biogenic Monoamines; Brain; Corticosterone; Depressive Disorder; Disease Model | 2017 |
Agmatine attenuates chronic unpredictable mild stress-induced anxiety, depression-like behaviours and cognitive impairment by modulating nitrergic signalling pathway.
Topics: Agmatine; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Chronic Di | 2017 |
The possible use of hypoxic preconditioning for the prophylaxis of post-stress depressive episodes.
Topics: Analysis of Variance; Animals; Atmospheric Pressure; Corticosterone; Depressive Disorder; Disease Mo | 2008 |
Increased phospholipase A2 activity and inflammatory response but decreased nerve growth factor expression in the olfactory bulbectomized rat model of depression: effects of chronic ethyl-eicosapentaenoate treatment.
Topics: Analysis of Variance; Animals; Celecoxib; Corticosterone; Corticotropin-Releasing Hormone; Cyclooxyg | 2009 |
Enriched environment experience overcomes learning deficits and depressive-like behavior induced by juvenile stress.
Topics: Age Factors; Animals; Anxiety; Behavior, Animal; Body Weight; Corticosterone; Depressive Disorder; E | 2009 |
Chronic social instability stress in female rats: a potential animal model for female depression.
Topics: Adrenal Glands; Animals; Body Temperature Regulation; Corticosterone; Depressive Disorder; Disease M | 2009 |
Antidepressant-like effects of rosiglitazone, a PPARγ agonist, in the rat forced swim and mouse tail suspension tests.
Topics: Anilides; Animals; Antidepressive Agents; Corticosterone; Depressive Disorder; Disease Models, Anima | 2009 |
Suicide attempt by jumping: a study of gonadal axis hormones in male suicide attempters versus men who fell by accident.
Topics: Accidental Falls; Adult; Age Factors; Aged; Corticosterone; Depressive Disorder; Humans; Male; Middl | 2009 |
Recapitulation and reversal of a persistent depression-like syndrome in rodents.
Topics: Animals; Anti-Inflammatory Agents; Chronic Disease; Corticosterone; Cyclic AMP Response Element-Bind | 2009 |
Susceptibility to stress in young rats after 2-week zinc deprivation.
Topics: Animals; Brain Chemistry; Corticosterone; Depressive Disorder; Dietary Supplements; Disease Models, | 2010 |
Prenatal thyroxine treatment disparately affects peripheral and amygdala thyroid hormone levels.
Topics: Amygdala; Animals; Anxiety; Corticosterone; Corticotropin-Releasing Hormone; Depressive Disorder; Di | 2010 |
Repeated anabolic androgenic steroid treatment causes antidepressant-reversible alterations of the hypothalamic-pituitary-adrenal axis, BDNF levels and behavior.
Topics: Anabolic Agents; Androgens; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Brain; Brai | 2010 |
gamma-Aminobutyric acid-type A receptor deficits cause hypothalamic-pituitary-adrenal axis hyperactivity and antidepressant drug sensitivity reminiscent of melancholic forms of depression.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depr | 2010 |
Early-life stress and antidepressants modulate peripheral biomarkers in a gene-environment rat model of depression.
Topics: Animals; Biomarkers; Brain-Derived Neurotrophic Factor; C-Reactive Protein; Citalopram; Corticostero | 2010 |
Simultaneous determination of urinary cortisol, cortisone and corticosterone in parachutists, depressed patients and healthy controls in view of biomedical and pharmacokinetic studies.
Topics: Analysis of Variance; Aviation; Chromatography, Reverse-Phase; Corticosterone; Cortisone; Depressive | 2011 |
Increased hippocampal tau phosphorylation and axonal mitochondrial transport in a mouse model of chronic stress.
Topics: Animals; Anxiety Disorders; Axonal Transport; Cells, Cultured; Chronic Disease; Corticosterone; Cort | 2012 |
Theanine intake improves the shortened lifespan, cognitive dysfunction and behavioural depression that are induced by chronic psychosocial stress in mice.
Topics: Animals; Chronic Disease; Cognition Disorders; Corticosterone; Depressive Disorder; Glutamates; Long | 2011 |
Beneficial behavioural and neurogenic effects of agomelatine in a model of depression/anxiety.
Topics: Acetamides; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; Cell Proliferati | 2012 |
Hypogonadism predisposes males to the development of behavioural and neuroplastic depressive phenotypes.
Topics: Animals; Corticosterone; Depressive Disorder; Disease Progression; Disease Susceptibility; Exercise | 2011 |
Vulnerability to depression: from brain neuroplasticity to identification of biomarkers.
Topics: Animals; Antidepressive Agents, Tricyclic; Biomarkers; Brain; Brain-Derived Neurotrophic Factor; Cel | 2011 |
A new anti-depressive strategy for the elderly: ablation of FKBP5/FKBP51.
Topics: Aged, 80 and over; Animals; Blotting, Western; Corticosterone; Depressive Disorder; Humans; Immunohi | 2011 |
Imipramine reverses depressive-like parameters in pneumococcal meningitis survivor rats.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Anhedonia; Animals; Antidepressive Agents, Tricyclic; B | 2012 |
Social defeat and isolation induce clear signs of a depression-like state, but modest cardiac alterations in wild-type rats.
Topics: Adrenal Glands; Animals; Autonomic Nervous System; Body Temperature; Choice Behavior; Circadian Rhyt | 2012 |
Chronic mild stress-induced depression-like symptoms in rats and abnormalities in catecholamine uptake in small arteries.
Topics: Analysis of Variance; Anhedonia; Animals; Arteries; Behavior, Animal; Blood Pressure; Catecholamines | 2012 |
Bupleurum falcatum prevents depression and anxiety-like behaviors in rats exposed to repeated restraint stress.
Topics: Animals; Antidepressive Agents; Anxiety; Brain; Bupleurum; Corticosterone; Depression; Depressive Di | 2012 |
Deletion of CREB-regulated transcription coactivator 1 induces pathological aggression, depression-related behaviors, and neuroplasticity genes dysregulation in mice.
Topics: Aggression; Animals; Antidepressive Agents, Second-Generation; Arabidopsis Proteins; Biogenic Monoam | 2012 |
NADPH oxidase mediates depressive behavior induced by chronic stress in mice.
Topics: Acetophenones; Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Antioxidants; Ascorb | 2012 |
Dim nighttime light impairs cognition and provokes depressive-like responses in a diurnal rodent.
Topics: Analysis of Variance; Animals; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Circadian Rhythm; C | 2012 |
Hippocampal nitric oxide contributes to sex difference in affective behaviors.
Topics: Androgens; Animals; Behavior, Animal; Chronic Disease; Corticosterone; CREB-Binding Protein; Depress | 2012 |
Chronic treatment with baicalin prevents the chronic mild stress-induced depressive-like behavior: involving the inhibition of cyclooxygenase-2 in rat brain.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain; Corticosterone; Cyclooxygenase 2 Inhibitors | 2013 |
PACAP-deficient mice show attenuated corticosterone secretion and fail to develop depressive behavior during chronic social defeat stress.
Topics: Animals; Behavior, Animal; Chronic Disease; Corticosterone; Depressive Disorder; Dominance-Subordina | 2013 |
Altered GABAergic and glutamatergic activity within the rat hippocampus and amygdala in rats subjected to repeated corticosterone administration but not restraint stress.
Topics: Amygdala; Animals; Behavior, Animal; Corticosterone; Depression; Depressive Disorder; Disease Models | 2013 |
Electroconvulsive seizures increase hippocampal neurogenesis after chronic corticosterone treatment.
Topics: Animals; Cell Count; Cell Death; Cell Division; Corticosterone; Depressive Disorder; Drug Administra | 2002 |
Evaluation of the effects of chronic mild stressors on hedonic and physiological responses: sex and strain compared.
Topics: Animals; Body Weight; Chronic Disease; Corticosterone; Depressive Disorder; Disease Models, Animal; | 2003 |
Evidence for alterations in alpha2-adrenergic receptor sensitivity in rats exposed to repeated cocaine administration.
Topics: Adrenergic alpha-Agonists; Animals; Brain; Clonidine; Cocaine; Cocaine-Related Disorders; Corticoste | 2004 |
Corticosterone strongly increases the affinity of dorsal raphe 5-HT1A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenalectomy; Animals; Corticosterone; Depressive Disorder; | 2004 |
Effects of rolipram, a phosphodiesterase 4 inhibitor, in combination with imipramine on depressive behavior, CRE-binding activity and BDNF level in learned helplessness rats.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived | 2004 |
Effect of combined treatment with imipramine and metyrapone on the immobility time, the activity of hypothalamo-pituitary-adrenocortical axis and immunological parameters in the forced swimming test in the rat.
Topics: Animals; Corticosterone; Depressive Disorder; Drug Therapy, Combination; Hypothalamo-Hypophyseal Sys | 2005 |
Recombinant human interferon-alpha does not alter reward behavior, or neuroimmune and neuroendocrine activation in rats.
Topics: Animals; Biogenic Monoamines; Brain Chemistry; Conditioning, Operant; Corticosterone; Depressive Dis | 2005 |
Effect of amantadine and imipramine on immunological parameters of rats subjected to a forced swimming test.
Topics: Amantadine; Animals; Cell Proliferation; Corticosterone; Cytokines; Depressive Disorder; Drug Therap | 2006 |
Mice with genetically altered glucocorticoid receptor expression show altered sensitivity for stress-induced depressive reactions.
Topics: Animals; Brain-Derived Neurotrophic Factor; Conditioning, Classical; Corticosterone; Depressive Diso | 2005 |
Corticosterone modulates auditory gating in mouse.
Topics: Animals; Anti-Inflammatory Agents; Auditory Pathways; Auditory Threshold; Brain; Corticosterone; Dep | 2006 |
Cyclic estradiol replacement attenuates stress-induced c-Fos expression in the PVN of ovariectomized rats.
Topics: Animals; Anxiety Disorders; Body Weight; Chronic Disease; Corticosterone; Depression, Postpartum; De | 2005 |
Urocortin 2-deficient mice exhibit gender-specific alterations in circadian hypothalamus-pituitary-adrenal axis and depressive-like behavior.
Topics: Adrenocorticotropic Hormone; Animals; Behavior, Animal; Brain; Cells, Cultured; Chimera; Circadian R | 2006 |
Persistent pain produces stress-like alterations in hippocampal neurogenesis and gene expression.
Topics: Animals; Antimetabolites; Behavior, Animal; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Ch | 2006 |
Curcumin reverses the effects of chronic stress on behavior, the HPA axis, BDNF expression and phosphorylation of CREB.
Topics: Adrenal Glands; Analysis of Variance; Animals; Body Weight; Brain-Derived Neurotrophic Factor; Corti | 2006 |
Aggressive behavior and HPA axis hormones after social isolation in adult rats of two different genetic animal models for depression.
Topics: Adaptation, Physiological; Adaptation, Psychological; Adrenocorticotropic Hormone; Aggression; Anima | 2006 |
Reduced anxiety and depression-like behaviors in mice lacking GABA transporter subtype 1.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; Behavior, Animal; Brain; Bra | 2007 |
Plasma corticosterone, dexamethasone (DEX) suppression and DEX/CRH tests in a rat model of genetic vulnerability to depression.
Topics: Analysis of Variance; Animals; Area Under Curve; Circadian Rhythm; Corticosterone; Corticotropin-Rel | 2007 |
Lithium blocks stress-induced changes in depressive-like behavior and hippocampal cell fate: the role of glycogen-synthase-kinase-3beta.
Topics: Adrenal Glands; Animals; Antimanic Agents; Behavior, Animal; Body Weight; Cell Proliferation; Cell S | 2008 |
Gene expression patterns in brain cortex of three different animal models of depression.
Topics: Adrenergic Uptake Inhibitors; Animals; Anti-Inflammatory Agents; Brain Chemistry; Cerebral Cortex; C | 2008 |
Lasting syndrome of depression produced by reduction in serotonin uptake during postnatal development: evidence from sleep, stress, and behavior.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Animals, Newborn; Antidepress | 2008 |
Inter-individual differences in novelty-seeking behavior in rats predict differential responses to desipramine in the forced swim test.
Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Brain Chemistry | 2008 |
ACTH and multisteroid responses to corticotropin-releasing factor in depressive illness: relationship to multisteroid responses after ACTH stimulation and dexamethasone suppression.
Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Adult; Aged; Corticosterone; Corticotropin-R | 1984 |
Brain part monoamines in the neuroendocrine mechanisms activated by immobilization stress in the rat.
Topics: Adrenocorticotropic Hormone; Animals; Brain Chemistry; Corticosterone; Depressive Disorder; Dopamine | 1984 |
Comparison of solid-phase radioimmunoassay and competitive protein binding method for postdexamethasone cortisol levels in psychiatric patients.
Topics: Bipolar Disorder; Corticosterone; Cross Reactions; Depressive Disorder; Dexamethasone; Humans; Hydro | 1983 |
Plasma dexamethasone concentrations and differential suppression response of cortisol and corticosterone in depressives and controls.
Topics: Adult; Aged; Bipolar Disorder; Corticosterone; Depressive Disorder; Dexamethasone; Diagnosis, Differ | 1984 |
Comparison of plasma cortisol and corticosterone in the dexamethasone suppression test for melancholia.
Topics: Bipolar Disorder; Corticosterone; Depressive Disorder; Dexamethasone; Female; Humans; Hydrocortisone | 1984 |
Animal model of depression: tests of three structurally and pharmacologically novel antidepressant compounds.
Topics: Animals; Antidepressive Agents; Bupropion; Corticosterone; Depressive Disorder; Disease Models, Anim | 1982 |
Dexamethasone suppression of 11-deoxycorticosterone, corticosterone and cortisol in depressed female patients and normal controls.
Topics: Adult; Corticosterone; Depressive Disorder; Desoxycorticosterone; Dexamethasone; Female; Humans; Hyd | 1982 |
Dexamethasone suppression test in female patients with endogenous depression: determinations of plasma corticosterone, 11-deoxycorticosterone, 11-deoxycortisol, cortisol and cortisone.
Topics: 17-Hydroxycorticosteroids; Adult; Bipolar Disorder; Corticosterone; Cortisone; Cortodoxone; Depressi | 1982 |
[Biochemical study of the animal model depression induced by tetrabenazine (author's transl)].
Topics: Animals; Behavior; Brain; Corticosterone; Depressive Disorder; Disease Models, Animal; Humans; Male; | 1980 |
Further analysis of the specificity of a novel animal model of depression--effects of an antihistaminic, antipsychotic and anxiolytic compound.
Topics: Animals; Corticosterone; Depressive Disorder; Disease Models, Animal; Exploratory Behavior; Haloperi | 1982 |
The effect of tianeptine and sertraline in three animal models of depression.
Topics: 1-Naphthylamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Antidepress | 1994 |
Corticosterone influences forced swim-induced immobility.
Topics: Animals; Behavior, Animal; Corticosterone; Depressive Disorder; Dose-Response Relationship, Drug; Ma | 1994 |
Indole-pyruvic acid, a tryptophan ketoanalogue, antagonizes the endocrine but not the behavioral effects of repeated stress in a model of depression.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Antidepressive Agents; Arousal; Corticosterone; Depr | 1993 |
Fawn-hooded rats show enhanced active behaviour in the forced swimming test, with no evidence for pituitary-adrenal axis hyperactivity.
Topics: Adrenal Glands; Animals; Behavior, Animal; Corticosterone; Depressive Disorder; Disease Models, Anim | 1996 |
The effects of central administration of neuropeptide Y on behavior, neurotransmitter, and immune functions in the olfactory bulbectomized rat model of depression.
Topics: Animals; Behavior, Animal; Corticosterone; Depressive Disorder; Exploratory Behavior; Hypothalamus; | 1996 |
Social isolation in animal models of relevance to neuropsychiatric disorders.
Topics: Animals; Arousal; Arvicolinae; Body Weight; Corticosterone; Depressive Disorder; Disease Models, Ani | 1996 |
Elevated basal trough levels of corticosterone suppress hippocampal 5-hydroxytryptamine(1A) receptor expression in adrenally intact rats: implication for the pathogenesis of depression.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenal Glands; Animals; Circadian Rhythm; Corticosterone; D | 1997 |
Effect of subchronic antidepressant treatments on behavioral, neurochemical, and endocrine changes in the forced-swim test.
Topics: Amygdala; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive A | 2000 |
Increased corticotropin-releasing factor concentrations in the bed nucleus of the stria terminalis of anhedonic rats.
Topics: Adrenocorticotropic Hormone; Animals; Behavior, Animal; Binding, Competitive; Corticosterone; Cortic | 2000 |
Diurnal variation of plasma corticosterone in depression.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Circadian Rhythm; Corticosterone; Depressive Disorde | 1990 |
Plasma corticosterone in dexamethasone suppression test on depressed patients.
Topics: Adrenal Cortex Function Tests; Adult; Aged; Bipolar Disorder; Corticosterone; Depressive Disorder; D | 1989 |
Adrenocortical steroid secretion and 11-beta-steroid hydroxylase activity after pituitary-adrenocortical probes in depression.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Bipolar Disorder; Corticosterone; Corticotropi | 1985 |
Specific determination of plasma dexamethasone by HPLC and RIA--application to standard dexamethasone suppression test in psychiatric patients.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Corticosterone; Depressive Disorder; Dexamethason | 1989 |
ACTH, cortisol, and corticosterone output after ovine corticotropin-releasing factor challenge during depression and after recovery.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Bipolar Disorder; Corticosterone; Corticotropin-Releasing | 1985 |
Cortisol and corticosterone response after syn-corticotropin in relationship to dexamethasone suppressibility of cortisol.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Corticosterone; Depressive Disorder; Dexamethasone; Female | 1986 |
Blunted aldosterone and ACTH release after human CRH administration in depressed patients.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Corticosterone; Corticotropin-Releasing Hormone; De | 1987 |
Learned helplessness: an experimental model of the DST in rats.
Topics: Animals; Corticosterone; Depressive Disorder; Dexamethasone; Electroshock; Helplessness, Learned; Hy | 1988 |
Stress and immunomodulation: the role of depression and neuroendocrine function.
Topics: Animals; Antibodies, Antinuclear; Antibody Formation; Corticosterone; Depressive Disorder; Humans; I | 1985 |
Plasma corticosterone and cortisol following dexamethasone in psychiatric patients.
Topics: Bipolar Disorder; Corticosterone; Depressive Disorder; Dexamethasone; Humans; Hydrocortisone; Hypoth | 1985 |
Alterations in cholinergic receptors mediate the effects of dexamethasone on corticosterone.
Topics: Animals; Corticosterone; Depressive Disorder; Dexamethasone; Humans; Kinetics; Male; Quinuclidinyl B | 1985 |