corticosterone has been researched along with Congenital Adrenal Hyperplasia in 75 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Forms of congenital adrenal hyperplasia resulting from deficient steroid hydroxylation at positions 21, 17 alpha, and 11 beta have several similar clinical and biochemical characteristics." | 5.27 | Distinctive plasma aldosterone, 18-hydroxycorticosterone, and 18-hydroxydeoxycorticosterone profile in the 21-, 17 alpha-, and 11 beta-hydroxylase deficiency types of congenital adrenal hyperplasia. ( Biglieri, EG; Kater, CE, 1983) |
| " The adrenals of patients with 17OHD synthesize 11-deoxycorticosterone (DOC) and corticosterone but no 19-carbon steroids, similar to the rodent adrenal, and DOC causes hypertension and hypokalemia." | 4.95 | Steroid 17-hydroxylase and 17,20-lyase deficiencies, genetic and pharmacologic. ( Auchus, RJ, 2017) |
| "To clarify the salt sensitivity of blood pressure in 17 alpha-hydroxylase deficiency (17 alpha-HD), a mineralocorticoid-induced hypertension, we examined the responses of blood pressure to salt loading (250 mEq/day for 6 days) after salt restriction (25 mEq/day for 3 days) in two 17 alpha-HD patients who had markedly high plasma deoxycorticosterone (DOC) (5." | 3.69 | Salt sensitivity of blood pressure in patients with 17 alpha-hydroxylase deficiency. ( Ando, K; Fujita, T; Nagase, M, 1994) |
| "In search for a biochemical marker to differentiate between adrenocortical carcinoma (AC) and adenoma (AA), plasma levels of the following steroids were studied preoperatively and postoperatively: 11-deoxycorticosterone (DOC), corticosterone (B), 11-deoxycortisol (S), and cortisol (F)." | 3.67 | Evidence of 11 beta-hydroxylase deficiency in childhood adrenocortical tumors. The plasma corticosterone/11-deoxycorticosterone ratio as a possible marker for malignancy. ( Bidlingmaier, F; Doerr, HG; Drop, SL; Knorr, D; Sippell, WG, 1987) |
| "The 0800 h plasma concentrations of the mineralocorticoid hormones, 18-hydroxydeoxycorticosterone (18-OHDOC), deoxycorticosterone (DOC), corticosterone, 18-hydroxycorticosterone (18-OHB), and aldosterone, in six patients with nonsalt-losing congenital adrenal hyperplasia revealed two groupings of these steroids: in one group, DOC, 18-OHB, and aldosterone were significantly elevated (P less than 0." | 3.66 | The zonal origins of the mineralocorticoid hormones in the 21-hydroxylation deficiency of congenital adrenal hyperplasia. ( Biglieri, EG; Kater, CE; Leme, CE; Malerbi, DA; Okada, H; Wajchenberg, BL, 1981) |
| "In 12 obligate heterozygotes for the simple virilizing form of congenital adrenal hyperplasia (21-hydroxylase deficiency), basal and ACTH-stimulated levels of aldosterone, corticosterone, deoxycorticosterone, 18-hydroxycorticosterone, and 18-hydroxydeoxycorticosterone were examined." | 3.66 | Impaired mineralocorticoid hormone responses to adrenocorticotropin stimulation: additional characterization of heterozygosity for the 21-hydroxylase deficiency type of congenital adrenal hyperplasia. ( Biglieri, EG; Kater, CE; Pardini, DP; Vieira, JG, 1983) |
| "A 17 year old female patient with hypertension, amenorrhoea and hirsutism was found to have subnormal levels of plasma and urinary cortisol, significant plasma levels of Reichstein's compound S and 21-deoxycortisol, high urinary levels of THS and pregnanetriolone as well as elevated levels of plasma and urinary testosterone." | 3.65 | A case of adrenogenital syndrome with aberrant 11beta-hydroxylation. ( Chowers, I; Finkelstein, M; Maschler, I; Muller, A; Shaefer, J; Slavin, S; Weidenfeld, J, 1977) |
| " However, current glucocorticoid replacement regimes are inadequate because doses sufficient to suppress excess androgens almost invariably induce adverse metabolic effects." | 1.43 | ABCC1 confers tissue-specific sensitivity to cortisol versus corticosterone: A rationale for safer glucocorticoid replacement therapy. ( Andrew, R; Elfick, AP; Homer, NZ; Livingstone, DE; Mackenzie, SD; Mole, DJ; Morgan, RA; Mouras, R; Nixon, M; Reynolds, RM; Stimson, RH; Taylor, AI; Walker, BR, 2016) |
| "Prenatal diagnosis of congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency by amniotic fluid (AF) steroid analysis is not possible in those cases in which prenatal dexamethasone (DEX) therapy is initiated to prevent virilization of female CAH fetuses because AF steroid levels are suppressed if DEX therapy is continued beyond amniocentesis (AC)." | 1.29 | Prenatal dexamethasone treatment in pregnancies at risk for congenital adrenal hyperplasia due to 21-hydroxylase deficiency: effect on midgestational amniotic fluid steroid levels. ( Dörr, HG; Sippell, WG, 1993) |
| "A case of male pseudohermaphroditism associated with 17 alpha-hydroxylase deficiency is reported in which the diagnosis was firmly established by gas chromatography-mass spectrometry." | 1.27 | Male pseudohermaphroditism due to 17 alpha-hydroxylase deficiency: diagnosis by gas chromatography--mass spectrometry. ( Betz, G; Burstein, P; Fennessey, P; Marsh, P, 1983) |
| "Forms of congenital adrenal hyperplasia resulting from deficient steroid hydroxylation at positions 21, 17 alpha, and 11 beta have several similar clinical and biochemical characteristics." | 1.27 | Distinctive plasma aldosterone, 18-hydroxycorticosterone, and 18-hydroxydeoxycorticosterone profile in the 21-, 17 alpha-, and 11 beta-hydroxylase deficiency types of congenital adrenal hyperplasia. ( Biglieri, EG; Kater, CE, 1983) |
| "The male pseudohermaphroditism resulted from deficient testosterone synthesis due to deficiency of 17 alpha-hydroxylase and 17,20 desmolase." | 1.27 | Male pseudohermaphroditism due to multiple defects in steroid-biosynthetic microsomal mixed-function oxidases. A new variant of congenital adrenal hyperplasia. ( Gautier, T; Imperato-McGinley, J; Peterson, RE; Shackleton, C, 1985) |
| "Light microscopy was compatible with Leydig cell tumor." | 1.26 | Cortisol production by testicular tumors in a patient with congenital adrenal hyperplasia (21-hydroxylase deficiency). ( Antonipillai, I; Franco-Saenz, R; Kropp, K; McCorquodale, M; Mulrow, PJ; Tan, SY, 1981) |
| "Corticosterone levels were 70 and 92 ng/ml and rose after ACTH (110 and 180 ng/ml)." | 1.26 | Dexamethasone-suppressible hypercorticosteronism in two 46,XX subjects with ambiguous genitalia and ovarian cysts. Partial defect of 17 alpha-hydroxylase or 17-20-desmolase. ( Canlorbe, P; Dehennin, L; Girard, F; Konopka, P; Merceron, RE; Roger, M; Seneze, J; Toublanc, JE, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 43 (57.33) | 18.7374 |
| 1990's | 12 (16.00) | 18.2507 |
| 2000's | 7 (9.33) | 29.6817 |
| 2010's | 10 (13.33) | 24.3611 |
| 2020's | 3 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, M | 1 |
| Mueller, JW | 1 |
| Gilligan, LC | 1 |
| Taylor, AE | 1 |
| Shaheen, F | 1 |
| Noczyńska, A | 1 |
| T'Sjoen, G | 1 |
| Denvir, L | 1 |
| Shenoy, S | 1 |
| Fulton, P | 1 |
| Cheetham, TD | 1 |
| Gleeson, H | 1 |
| Rahman, M | 1 |
| Krone, NP | 1 |
| Taylor, NF | 1 |
| Shackleton, CHL | 1 |
| Arlt, W | 1 |
| Idkowiak, J | 1 |
| Wang, M | 2 |
| Milic, M | 1 |
| Gericke, A | 1 |
| Mercieca, K | 1 |
| Liu, H | 1 |
| Ruan, Y | 1 |
| Jiang, S | 1 |
| van Beers, T | 1 |
| von Pein, HD | 1 |
| Müller, MB | 1 |
| Prokosch, V | 1 |
| Seven Menevse, T | 1 |
| Kendir Demirkol, Y | 1 |
| Gurpinar Tosun, B | 1 |
| Bayramoglu, E | 1 |
| Yildiz, M | 1 |
| Acar, S | 1 |
| Erisen Karaca, S | 1 |
| Orbak, Z | 1 |
| Onder, A | 1 |
| Sobu, E | 1 |
| Anık, A | 1 |
| Atay, Z | 1 |
| Bugrul, F | 1 |
| Derya Bulus, A | 1 |
| Demir, K | 1 |
| Dogan, D | 1 |
| Cihan Emeksiz, H | 1 |
| Kirmizibekmez, H | 1 |
| Ozcan Murat, N | 1 |
| Yaman, A | 1 |
| Turan, S | 1 |
| Bereket, A | 1 |
| Guran, T | 1 |
| Qin, F | 1 |
| Liu, K | 1 |
| Zhang, C | 1 |
| Sun, X | 1 |
| Zhang, Y | 1 |
| Wu, Y | 1 |
| Ma, W | 1 |
| Wang, W | 1 |
| Wu, X | 1 |
| Qin, Y | 1 |
| Zou, Y | 1 |
| Zhou, X | 1 |
| Jiang, X | 1 |
| Wu, H | 1 |
| Hui, R | 1 |
| Wang, J | 1 |
| Zhang, H | 1 |
| Song, L | 1 |
| Kulle, AE | 1 |
| Riepe, FG | 1 |
| Hedderich, J | 1 |
| Sippell, WG | 3 |
| Schmitz, J | 1 |
| Niermeyer, L | 1 |
| Holterhus, PM | 1 |
| Auchus, RJ | 2 |
| Nixon, M | 1 |
| Mackenzie, SD | 1 |
| Taylor, AI | 1 |
| Homer, NZ | 1 |
| Livingstone, DE | 1 |
| Mouras, R | 1 |
| Morgan, RA | 1 |
| Mole, DJ | 1 |
| Stimson, RH | 1 |
| Reynolds, RM | 1 |
| Elfick, AP | 1 |
| Andrew, R | 1 |
| Walker, BR | 1 |
| Feldhaus, AL | 1 |
| Anderson, K | 1 |
| Dutzar, B | 1 |
| Ojala, E | 1 |
| McNeill, PD | 1 |
| Fan, P | 1 |
| Mulligan, J | 1 |
| Marzolf, S | 1 |
| Karasek, C | 1 |
| Scalley-Kim, M | 1 |
| Stewart, E | 1 |
| Billgren, J | 1 |
| Rubin, V | 1 |
| Schneider, K | 1 |
| Jurchen, D | 1 |
| Snow, K | 1 |
| Barnett, S | 1 |
| Bengtsson, B | 1 |
| Baker, B | 1 |
| Latham, JA | 1 |
| Allison, D | 1 |
| Garcia-Martinez, LF | 1 |
| Costa-Barbosa, FA | 1 |
| Carvalho, VM | 1 |
| Nakamura, OH | 1 |
| Bachega, TA | 1 |
| Vieira, JG | 2 |
| Kater, CE | 5 |
| Yamada, Y | 2 |
| Sekihara, H | 2 |
| Tsai, LC | 1 |
| Beavo, JA | 1 |
| Abrahams, L | 1 |
| Semjonous, NM | 1 |
| Guest, P | 1 |
| Zielinska, A | 1 |
| Hughes, B | 1 |
| Lavery, GG | 1 |
| Stewart, PM | 1 |
| Kalani, A | 1 |
| Bahtiyar, G | 1 |
| Sacerdote, A | 1 |
| Li, H | 1 |
| Brochu, M | 1 |
| Wang, SP | 1 |
| Rochdi, L | 1 |
| Côté, M | 1 |
| Mitchell, G | 1 |
| Gallo-Payet, N | 1 |
| SPANAR, E | 1 |
| ADAMEC, O | 1 |
| KYSELA, J | 1 |
| VILLEE, DB | 2 |
| Perez, MS | 1 |
| Benencia, H | 1 |
| Frechtel, GD | 1 |
| Esteban, EO | 1 |
| Gil, MC | 1 |
| Targovnik, HM | 1 |
| Marquez, NB | 1 |
| Wei, JQ | 2 |
| Wei, JL | 2 |
| Li, WC | 1 |
| Bi, YS | 1 |
| Wei, FC | 1 |
| Paterson, JM | 1 |
| Holmes, MC | 1 |
| Kenyon, CJ | 1 |
| Carter, R | 1 |
| Mullins, JJ | 1 |
| Seckl, JR | 1 |
| Shih, MC | 1 |
| Hsu, NC | 1 |
| Huang, CC | 1 |
| Wu, TS | 1 |
| Lai, PY | 1 |
| Chung, BC | 1 |
| Bacchus, H | 1 |
| Gordon, RC | 1 |
| Kelsey, WM | 1 |
| Franco-Saenz, R | 1 |
| Antonipillai, I | 1 |
| Tan, SY | 1 |
| McCorquodale, M | 1 |
| Kropp, K | 1 |
| Mulrow, PJ | 1 |
| Biglieri, EG | 8 |
| Wajchenberg, BL | 1 |
| Malerbi, DA | 1 |
| Okada, H | 1 |
| Leme, CE | 1 |
| Tvedegaard, E | 1 |
| Frederiksen, V | 1 |
| Olgaard, K | 1 |
| Nielsen, MD | 1 |
| Starup, J | 1 |
| Roger, M | 2 |
| Merceron, RE | 1 |
| Girard, F | 1 |
| Canlorbe, P | 1 |
| Dehennin, L | 1 |
| Konopka, P | 1 |
| Seneze, J | 1 |
| Toublanc, JE | 1 |
| de Gennes, JL | 1 |
| Jambart, S | 1 |
| Turpin, G | 1 |
| Elkik, F | 1 |
| Burstein, P | 1 |
| Marsh, P | 1 |
| Fennessey, P | 1 |
| Betz, G | 2 |
| D'Armiento, M | 1 |
| Reda, G | 1 |
| Kater, C | 1 |
| Shackleton, CH | 3 |
| Fennessey, PV | 1 |
| Marsh, PG | 1 |
| Orr, ER | 1 |
| Burnstein, P | 1 |
| Pardini, DP | 1 |
| Watanabe, F | 1 |
| Ryota, T | 1 |
| Kobayashi, Y | 1 |
| Mininberg, DT | 1 |
| Levine, LS | 1 |
| New, MI | 3 |
| Brust, N | 1 |
| Chang, B | 1 |
| Hirai, J | 1 |
| Nagase, M | 1 |
| Ando, K | 1 |
| Fujita, T | 1 |
| Martin-Du Pan, RC | 1 |
| Dahoun, S | 1 |
| Stalberg, A | 1 |
| Campana, A | 1 |
| Dörr, HG | 1 |
| Neuwinger, J | 1 |
| Licht, P | 1 |
| Munzer, B | 1 |
| Sir-Petermann, T | 1 |
| Siebzehnrübl, E | 1 |
| Wildt, L | 1 |
| Caron, KM | 1 |
| Soo, SC | 1 |
| Wetsel, WC | 1 |
| Stocco, DM | 1 |
| Clark, BJ | 1 |
| Parker, KL | 1 |
| Grumbach, MM | 1 |
| Shaw, EB | 1 |
| Bornstein, SR | 1 |
| Tajima, T | 2 |
| Eisenhofer, G | 1 |
| Haidan, A | 1 |
| Aguilera, G | 2 |
| Okada, T | 1 |
| Ma, XM | 1 |
| Ramsey, W | 1 |
| Bornstein, S | 1 |
| Honour, JW | 3 |
| Tourniaire, J | 1 |
| Shackleton, HL | 1 |
| Waldhäusl, W | 1 |
| Herkner, K | 1 |
| Nowotny, P | 1 |
| Bratusch-Marrain, P | 1 |
| Roitman, E | 1 |
| West, CD | 1 |
| Atcheson, JB | 1 |
| Stanchfield, JB | 1 |
| Rallison, ML | 1 |
| Chavré, VJ | 1 |
| Tyler, FH | 1 |
| Maschler, I | 1 |
| Weidenfeld, J | 1 |
| Muller, A | 1 |
| Slavin, S | 1 |
| Shaefer, J | 1 |
| Chowers, I | 1 |
| Finkelstein, M | 1 |
| Teofili, MT | 1 |
| Vecchi, L | 1 |
| Crigler, JF | 1 |
| Toaff, ME | 1 |
| Toaff, R | 1 |
| Chayen, R | 1 |
| Lucarelli, C | 1 |
| Zhou, XT | 1 |
| Wang, DQ | 1 |
| Dai, WJ | 1 |
| Li, S | 1 |
| Li, SM | 1 |
| Liu, RT | 1 |
| Moreira, AC | 1 |
| Leal, AM | 1 |
| Castro, M | 1 |
| Pang, S | 1 |
| Yang, X | 1 |
| Tissot, R | 1 |
| Nino, M | 1 |
| Manaligod, J | 1 |
| Bullock, LP | 1 |
| Mason, JI | 1 |
| Chapman, TE | 1 |
| Kraan, GP | 1 |
| Nagel, GT | 1 |
| Wolthers, BG | 1 |
| Drayer, NM | 1 |
| Peterson, RE | 2 |
| Imperato-McGinley, J | 1 |
| Gautier, T | 1 |
| Shackleton, C | 1 |
| Blau, N | 1 |
| Zachmann, M | 2 |
| Kempken, B | 1 |
| Staudenmann, W | 1 |
| Möhr, E | 1 |
| Curtius, HC | 1 |
| Doerr, HG | 1 |
| Drop, SL | 1 |
| Bidlingmaier, F | 1 |
| Knorr, D | 1 |
| Goldman, AS | 5 |
| Winter, JS | 1 |
| Scriba, PC | 1 |
| Hacker, R | 1 |
| Dieterle, P | 1 |
| Kluge, F | 1 |
| Hochheuser, W | 1 |
| Schwarz, K | 1 |
| Mallin, SR | 1 |
| Miura, K | 1 |
| Seaman, MP | 2 |
| Neumann, F | 1 |
| Mori, N | 1 |
| Miyakawa, I | 1 |
| Rappaport, R | 1 |
| Cornu, G | 1 |
| Royer, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Natural History Study of Patients With Excess Androgen[NCT00250159] | 3,000 participants (Anticipated) | Observational | 2006-01-02 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for corticosterone and Congenital Adrenal Hyperplasia
| Article | Year |
|---|---|
Steroid 17-hydroxylase and 17,20-lyase deficiencies, genetic and pharmacologic.
Topics: Abiraterone Acetate; Adrenal Hyperplasia, Congenital; Animals; Antihypertensive Agents; Corticostero | 2017 |
The roles of cyclic nucleotide phosphodiesterases (PDEs) in steroidogenesis.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adrenal Cortex; Adrenal Hy | 2011 |
[Corticosterone].
Topics: ACTH Syndrome, Ectopic; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Biomarkers; Cortic | 2005 |
The genetics, pathophysiology, and management of human deficiencies of P450c17.
Topics: Adrenal Hyperplasia, Congenital; Corticosterone; Desoxycorticosterone; Humans; Mutation; Steroid 17- | 2001 |
The adrenogenital syndrome.
Topics: Adrenal Hyperplasia, Congenital; Corticosterone; Cortodoxone; Female; Glucocorticoids; Humans; Hydro | 1976 |
[Adrenal cortex function tests and their interpretation].
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Aldosterone; Androg | 1969 |
1 trial available for corticosterone and Congenital Adrenal Hyperplasia
| Article | Year |
|---|---|
A method for the simultaneous determination of the secretion rates of cortisol, 11-desoxycortisol, corticosterone, 11-desoxycorticosterone and aldosterone.
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adult; Aldosterone; Carbon Isotopes; Child; Child, Pres | 1969 |
68 other studies available for corticosterone and Congenital Adrenal Hyperplasia
| Article | Year |
|---|---|
The broad phenotypic spectrum of 17α-hydroxylase/17,20-lyase (CYP17A1) deficiency: a case series.
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Amenorrhea; Computer Simulation; Corticosterone; Failur | 2021 |
Chronic social defeat stress causes retinal vascular dysfunction.
Topics: Actins; Adrenal Hyperplasia, Congenital; Animals; Cell Survival; Chronic Disease; Corticosterone; Di | 2021 |
Steroid Hormone Profiles and Molecular Diagnostic Tools in Pediatric Patients With non-CAH Primary Adrenal Insufficiency.
Topics: Addison Disease; Adrenal Hyperplasia, Congenital; Child; Child, Preschool; Corticosterone; Cortisone | 2022 |
Steroid metabolism gene variants and their genotype-phenotype correlations in Chinese early-onset hypertension patients.
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adult; Child; Corticosterone; G Protein-Coupled Inwardl | 2019 |
LC-MS/MS based determination of basal- and ACTH-stimulated plasma concentrations of 11 steroid hormones: implications for detecting heterozygote CYP21A2 mutation carriers.
Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormo | 2015 |
ABCC1 confers tissue-specific sensitivity to cortisol versus corticosterone: A rationale for safer glucocorticoid replacement therapy.
Topics: Addison Disease; Adipose Tissue; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Anima | 2016 |
ALD1613, a Novel Long-Acting Monoclonal Antibody to Control ACTH-Driven Pharmacology.
Topics: Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Animals; Antibodies, Monoclonal; Antib | 2017 |
Zona fasciculata 21-hydroxysteroids and precursor-to-product ratios in 21-hydroxylase deficiency: further characterization of classic and non-classic patients and heterozygote carriers.
Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Adult; Carrier State; Corticosterone; | 2011 |
[Corticosterone, deoxycorticosterone].
Topics: Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Corticosterone; Desoxycorticosterone; Fema | 2010 |
Biomarkers of hypothalamic-pituitary-adrenal axis activity in mice lacking 11β-HSD1 and H6PDH.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adrenal Glands; Adrenal Hyperplasia, Congenital; Animal | 2012 |
Ashwagandha root in the treatment of non-classical adrenal hyperplasia.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Hyperplasia, Congenital; Corticosterone; Diagnosis, Differenti | 2012 |
Hormone-sensitive lipase deficiency in mice causes lipid storage in the adrenal cortex and impaired corticosterone response to corticotropin stimulation.
Topics: Adrenal Cortex; Adrenal Hyperplasia, Congenital; Adrenal Medulla; Adrenocorticotropic Hormone; Aldos | 2002 |
[Diagnostic peculiarities of steroid hormone analysis in specific forms of the adrenogenital syndrome].
Topics: 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Adrenogenital Syndrome; Corticosterone; Dexamethas | 1963 |
EFFECTS OF SUBSTRATES AND COFACTORS ON STEROID SYNTHESIS IN HYPERPLASTIC ADRENALS.
Topics: Adolescent; Adrenal Cortex Hormones; Adrenal Glands; Adrenal Hyperplasia, Congenital; Carbon Isotope | 1964 |
17alpha-hydroxylase deficiency : biochemical and molecular findings in two sisters and their family.
Topics: Adrenal Hyperplasia, Congenital; Aldosterone; Amino Acid Sequence; Base Sequence; Corticosterone; Ex | 2004 |
Genotyping of five chinese patients with 17alpha-hydroxylase deficiency diagnosed through high-performance liquid chromatography serum adrenal profile: identification of two novel CYP17 mutations.
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adult; Base Sequence; China; Chromatography, High Press | 2006 |
Liver-selective transgene rescue of hypothalamic-pituitary-adrenal axis dysfunction in 11beta-hydroxysteroid dehydrogenase type 1-deficient mice.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adrenal Glands; Adrenal Hyperplasia, Congenital; Animal | 2007 |
Mutation of mouse Cyp11a1 promoter caused tissue-specific reduction of gene expression and blunted stress response without affecting reproduction.
Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Animals; Binding Sites; Blotting, Western; Choleste | 2008 |
A method for measurement of total 17-OH, 21-methyl steroids in the urine and its application to clinical problems.
Topics: 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Hyperplasia, Con | 1967 |
Pseudotumor cerebri in congenital adrenal hyperplasia.
Topics: Adrenal Cortex Hormones; Adrenal Hyperplasia, Congenital; Brain Diseases; Child; Corticosterone; Cor | 1967 |
Cortisol production by testicular tumors in a patient with congenital adrenal hyperplasia (21-hydroxylase deficiency).
Topics: Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Chorionic Gonadotropin; Cortico | 1981 |
The zonal origins of the mineralocorticoid hormones in the 21-hydroxylation deficiency of congenital adrenal hyperplasia.
Topics: 18-Hydroxycorticosterone; 18-Hydroxydesoxycorticosterone; Adolescent; Adrenal Cortex; Adrenal Hyperp | 1981 |
Two cases of 17 alpha-hydroxylase deficiency--one combined with complete gonadal agenesis.
Topics: 17-Ketosteroids; Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Al | 1981 |
Dexamethasone-suppressible hypercorticosteronism in two 46,XX subjects with ambiguous genitalia and ovarian cysts. Partial defect of 17 alpha-hydroxylase or 17-20-desmolase.
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Aldosterone; Corticosteron | 1982 |
17 alpha-hydroxylase deficiency syndrome associated with bilateral streak gonads and impaired development of Müllerian ducts derivatives. Report of a case.
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Aldosterone; Amenorrhea; C | 1982 |
Male pseudohermaphroditism due to 17 alpha-hydroxylase deficiency: diagnosis by gas chromatography--mass spectrometry.
Topics: Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Corticosterone; Cross Reactions | 1983 |
17 alpha-hydroxylase deficiency: mineralocorticoid hormone profiles in an affected family.
Topics: 18-Hydroxycorticosterone; 18-Hydroxydesoxycorticosterone; Adolescent; Adrenal Hyperplasia, Congenita | 1983 |
Determination of steroid profiles in healthy and diseased states: identification and quantitation of a block of 17 alpha-hydroxylase.
Topics: Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Androgens; Chorionic Gonadotrop | 1983 |
Impaired mineralocorticoid hormone responses to adrenocorticotropin stimulation: additional characterization of heterozygosity for the 21-hydroxylase deficiency type of congenital adrenal hyperplasia.
Topics: 17-alpha-Hydroxyprogesterone; 18-Hydroxycorticosterone; 18-Hydroxydesoxycorticosterone; Adrenal Hype | 1983 |
Enzyme immunoassay for serum 18-hydroxycorticosterone and its clinical application.
Topics: 18-Hydroxycorticosterone; ACTH Syndrome, Ectopic; Addison Disease; Adenoma; Adrenal Hyperplasia, Con | 1984 |
Distinctive plasma aldosterone, 18-hydroxycorticosterone, and 18-hydroxydeoxycorticosterone profile in the 21-, 17 alpha-, and 11 beta-hydroxylase deficiency types of congenital adrenal hyperplasia.
Topics: 18-Hydroxycorticosterone; 18-Hydroxydesoxycorticosterone; Adolescent; Adrenal Hyperplasia, Congenita | 1983 |
Current concepts in congenital adrenal hyperplasia.
Topics: 17-Hydroxycorticosteroids; Adrenal Hyperplasia, Congenital; Child, Preschool; Cholesterol Side-Chain | 1982 |
The unique patterns of plasma aldosterone and 18-hydroxycorticosterone concentrations in the 17 alpha-hydroxylase deficiency syndrome.
Topics: 18-Hydroxycorticosterone; 18-Hydroxydesoxycorticosterone; Adrenal Hyperplasia, Congenital; Adult; Al | 1982 |
Salt sensitivity of blood pressure in patients with 17 alpha-hydroxylase deficiency.
Topics: Adrenal Hyperplasia, Congenital; Adult; Blood Pressure; Corticosterone; Desoxycorticosterone; Humans | 1994 |
[Primary amenorrhea and arterial hypertension in a case of 17 alpha-hydroxylase deficiency].
Topics: Adrenal Hyperplasia, Congenital; Adult; Aldosterone; Amenorrhea; Corticosterone; Desoxycorticosteron | 1994 |
Prenatal dexamethasone treatment in pregnancies at risk for congenital adrenal hyperplasia due to 21-hydroxylase deficiency: effect on midgestational amniotic fluid steroid levels.
Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Aldosterone; Amniocentesis; Amniotic | 1993 |
Substitution with testosterone as aromatizable substrate for induction of follicular maturation, estradiol production and ovulation in a patient with 17 alpha-hydroxylase deficiency.
Topics: Adrenal Hyperplasia, Congenital; Adult; Corticosterone; Estradiol; Female; Humans; Ovarian Follicle; | 1996 |
Targeted disruption of the mouse gene encoding steroidogenic acute regulatory protein provides insights into congenital lipoid adrenal hyperplasia.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormon | 1997 |
Further studies on the treatment of congenital adrenal hyperplasia with cortisone: IV. Effect of cortisone and compound B in infants with disturbed electrolyte metabolism, by John F. Crigler Jr, MD, Samuel H. Silverman, MD, and Lawson Wilkins, MD, Pediatr
Topics: Adrenal Hyperplasia, Congenital; Corticosterone; Cortisone; History, 20th Century; Humans; Infant | 1998 |
Adrenomedullary function is severely impaired in 21-hydroxylase-deficient mice.
Topics: Adrenal Hyperplasia, Congenital; Adrenal Medulla; Animals; Base Sequence; Catecholamines; Chromaffin | 1999 |
Restoration of adrenal steroidogenesis by adenovirus-mediated transfer of human cytochromeP450 21-hydroxylase into the adrenal gland of21-hydroxylase-deficient mice.
Topics: Adenoviridae; Adrenal Glands; Adrenal Hyperplasia, Congenital; Animals; Corticosterone; Female; Gene | 1999 |
Mechanisms establishing the mineralocorticoid hormone patterns in the 17 alpha-hydroxylase deficiency syndrome.
Topics: 18-Hydroxycorticosterone; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Aldos | 1979 |
Urinary steroid excretion in 17 alpha-hydroxylase deficiency.
Topics: 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Corticosterone; Desoxycorticosterone; Humans; Hydr | 1978 |
Differences in metabolism of corticosterone by the newborn and adult human.
Topics: Adrenal Hyperplasia, Congenital; Adult; Aldosterone; Corticosterone; Humans; Infant, Newborn; Steroi | 1978 |
Combined 17 alpha- and 18-hydroxylase deficiency associated with complete male pseudohermaphroditism and hypoaldosteronism.
Topics: Adrenal Hyperplasia, Congenital; Aldosterone; Corticosterone; Desoxycorticosterone; Disorders of Sex | 1978 |
Metabolism of radiolabeled corticosterone in an adult with the 17 alpha-hydroxylase deficiency syndrome.
Topics: Adrenal Hyperplasia, Congenital; Adult; Chromatography, Gas; Corticosterone; Female; Humans; Mass Sp | 1979 |
Multiple or single 21-hydroxylases in congenital adrenal hyperplasia?
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adult; Child; Circadian Rhythm; Corticosterone; Female; | 1979 |
A case of adrenogenital syndrome with aberrant 11beta-hydroxylation.
Topics: 17-Ketosteroids; Adolescent; Adrenal Hyperplasia, Congenital; Amenorrhea; Corticosterone; Female; Hi | 1977 |
[Main enzymatic disorders of the adrenal cortex and their therapeutic possibilities].
Topics: Adrenal Cortex; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Corticosterone; Femal | 1978 |
Congenital adrenal hyperplasia caused by 11 beta-hydroxylase deficiency with onset of symptoms after one spontaneous pregnancy.
Topics: 17-Ketosteroids; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adult; Androgens; Chromatography, | 1975 |
Serum steroid hormonal profiles by reversed-phase liquid chromatography in patients with 17-hydroxylase deficiency and in an affected family.
Topics: Adolescent; Adrenal Cortex Hormones; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; A | 1992 |
Adrenocorticotropin-corticosterone relationship during dexamethasone therapy in 17 alpha-hydroxylase deficiency.
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Aldosterone; Corticosteron | 1992 |
Inherited congenital adrenal hyperplasia in the rabbit: absent cholesterol side-chain cleavage cytochrome P450 gene expression.
Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Animals; Blotting, Northern; Cholesterol Side-Chain | 1992 |
Measurement of the cortisol production rate in two sisters with 17 alpha-hydroxylase deficiency using [1,2,3,4-13C]cortisol and isotope dilution mass spectrometry.
Topics: Adrenal Hyperplasia, Congenital; Carbon Isotopes; Child; Child, Preschool; Chromatography, High Pres | 1991 |
Male pseudohermaphroditism due to multiple defects in steroid-biosynthetic microsomal mixed-function oxidases. A new variant of congenital adrenal hyperplasia.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; 18-Hydroxycorticosterone; 18-Hydroxydesoxycorticosterone | 1985 |
Identification of new steroids in patients with 17 alpha-hydroxylase deficiency by capillary gas chromatography/mass spectrometry.
Topics: Adrenal Hyperplasia, Congenital; Corticosterone; Female; Gas Chromatography-Mass Spectrometry; Human | 1987 |
[Hirsutism and light forms of congenital adrenogenital syndrome with 21- and 11-beta hydroxylase defect].
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Aldosterone; Androgens; Child; Child, Preschool; Cortic | 1986 |
Evidence of 11 beta-hydroxylase deficiency in childhood adrenocortical tumors. The plasma corticosterone/11-deoxycorticosterone ratio as a possible marker for malignancy.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Hyperplasia, Congenital; Carcinoma; Child; Child, Prescho | 1987 |
Activities of various steroidogenic enzymes in two forms of experimental adrenal hyperplasia.
Topics: Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Animals; Corticosterone; Female; Fluor | 1967 |
[ACTH determination in the plasma from the cranial bulb of the jugular vein].
Topics: Addison Disease; Adolescent; Adrenal Hyperplasia, Congenital; Adrenal Insufficiency; Adrenalectomy; | 1966 |
Congenital adrenal hyperplasia secondary to 17-hydroxylase deficiency. Two sisters with amenorrhea, hypokalemia, hypertension, and cystic ovaries.
Topics: Adolescent; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Amenorrhea | 1969 |
Secretion rates of cortisol and aldosterone precursors in various forms of congenital adrenal hyperplasia.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hor | 1970 |
Prevention of Mammary gland defects in experimental congenital adrenal hyperplasia due to inhibition to 3 beta-hydroxysteroid dehydrogenase in rats.
Topics: Abnormalities, Drug-Induced; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Ho | 1970 |
Experimental model of congenital adrenal cortical hyperplasia produced in utero with an inhibitor of 11-beta-steroid hydroxylase.
Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Animals; Corticosteron | 1967 |
Congenital adrenogenital syndrome and successful pregnancy. Report of a case.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Gland Diseases; Adrenal Hyperplasia, | 1970 |
Experimental congenital lipoid adrenal hyperplasia: prevention of anatomic defects produced by aminoglutethimide.
Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Aminoglutethimide; Aniline Compounds; Animals; Anti | 1970 |
Statural growth in congenital adrenal hyperplasia treated with hydrocortisone.
Topics: Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Body Height; Bone Development; Child, | 1968 |
Prevention of anatomic defects in congenital adrenal hyperplasia produced by estradiol-17-beta in rats.
Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Animals; Clitoris; Corticosterone; Estrogen Antagon | 1969 |