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corticosterone and Congenital Adrenal Hyperplasia

corticosterone has been researched along with Congenital Adrenal Hyperplasia in 75 studies

Research Excerpts

ExcerptRelevanceReference
"Forms of congenital adrenal hyperplasia resulting from deficient steroid hydroxylation at positions 21, 17 alpha, and 11 beta have several similar clinical and biochemical characteristics."5.27Distinctive plasma aldosterone, 18-hydroxycorticosterone, and 18-hydroxydeoxycorticosterone profile in the 21-, 17 alpha-, and 11 beta-hydroxylase deficiency types of congenital adrenal hyperplasia. ( Biglieri, EG; Kater, CE, 1983)
" The adrenals of patients with 17OHD synthesize 11-deoxycorticosterone (DOC) and corticosterone but no 19-carbon steroids, similar to the rodent adrenal, and DOC causes hypertension and hypokalemia."4.95Steroid 17-hydroxylase and 17,20-lyase deficiencies, genetic and pharmacologic. ( Auchus, RJ, 2017)
"To clarify the salt sensitivity of blood pressure in 17 alpha-hydroxylase deficiency (17 alpha-HD), a mineralocorticoid-induced hypertension, we examined the responses of blood pressure to salt loading (250 mEq/day for 6 days) after salt restriction (25 mEq/day for 3 days) in two 17 alpha-HD patients who had markedly high plasma deoxycorticosterone (DOC) (5."3.69Salt sensitivity of blood pressure in patients with 17 alpha-hydroxylase deficiency. ( Ando, K; Fujita, T; Nagase, M, 1994)
"In search for a biochemical marker to differentiate between adrenocortical carcinoma (AC) and adenoma (AA), plasma levels of the following steroids were studied preoperatively and postoperatively: 11-deoxycorticosterone (DOC), corticosterone (B), 11-deoxycortisol (S), and cortisol (F)."3.67Evidence of 11 beta-hydroxylase deficiency in childhood adrenocortical tumors. The plasma corticosterone/11-deoxycorticosterone ratio as a possible marker for malignancy. ( Bidlingmaier, F; Doerr, HG; Drop, SL; Knorr, D; Sippell, WG, 1987)
"The 0800 h plasma concentrations of the mineralocorticoid hormones, 18-hydroxydeoxycorticosterone (18-OHDOC), deoxycorticosterone (DOC), corticosterone, 18-hydroxycorticosterone (18-OHB), and aldosterone, in six patients with nonsalt-losing congenital adrenal hyperplasia revealed two groupings of these steroids: in one group, DOC, 18-OHB, and aldosterone were significantly elevated (P less than 0."3.66The zonal origins of the mineralocorticoid hormones in the 21-hydroxylation deficiency of congenital adrenal hyperplasia. ( Biglieri, EG; Kater, CE; Leme, CE; Malerbi, DA; Okada, H; Wajchenberg, BL, 1981)
"In 12 obligate heterozygotes for the simple virilizing form of congenital adrenal hyperplasia (21-hydroxylase deficiency), basal and ACTH-stimulated levels of aldosterone, corticosterone, deoxycorticosterone, 18-hydroxycorticosterone, and 18-hydroxydeoxycorticosterone were examined."3.66Impaired mineralocorticoid hormone responses to adrenocorticotropin stimulation: additional characterization of heterozygosity for the 21-hydroxylase deficiency type of congenital adrenal hyperplasia. ( Biglieri, EG; Kater, CE; Pardini, DP; Vieira, JG, 1983)
"A 17 year old female patient with hypertension, amenorrhoea and hirsutism was found to have subnormal levels of plasma and urinary cortisol, significant plasma levels of Reichstein's compound S and 21-deoxycortisol, high urinary levels of THS and pregnanetriolone as well as elevated levels of plasma and urinary testosterone."3.65A case of adrenogenital syndrome with aberrant 11beta-hydroxylation. ( Chowers, I; Finkelstein, M; Maschler, I; Muller, A; Shaefer, J; Slavin, S; Weidenfeld, J, 1977)
" However, current glucocorticoid replacement regimes are inadequate because doses sufficient to suppress excess androgens almost invariably induce adverse metabolic effects."1.43ABCC1 confers tissue-specific sensitivity to cortisol versus corticosterone: A rationale for safer glucocorticoid replacement therapy. ( Andrew, R; Elfick, AP; Homer, NZ; Livingstone, DE; Mackenzie, SD; Mole, DJ; Morgan, RA; Mouras, R; Nixon, M; Reynolds, RM; Stimson, RH; Taylor, AI; Walker, BR, 2016)
"Prenatal diagnosis of congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency by amniotic fluid (AF) steroid analysis is not possible in those cases in which prenatal dexamethasone (DEX) therapy is initiated to prevent virilization of female CAH fetuses because AF steroid levels are suppressed if DEX therapy is continued beyond amniocentesis (AC)."1.29Prenatal dexamethasone treatment in pregnancies at risk for congenital adrenal hyperplasia due to 21-hydroxylase deficiency: effect on midgestational amniotic fluid steroid levels. ( Dörr, HG; Sippell, WG, 1993)
"A case of male pseudohermaphroditism associated with 17 alpha-hydroxylase deficiency is reported in which the diagnosis was firmly established by gas chromatography-mass spectrometry."1.27Male pseudohermaphroditism due to 17 alpha-hydroxylase deficiency: diagnosis by gas chromatography--mass spectrometry. ( Betz, G; Burstein, P; Fennessey, P; Marsh, P, 1983)
"Forms of congenital adrenal hyperplasia resulting from deficient steroid hydroxylation at positions 21, 17 alpha, and 11 beta have several similar clinical and biochemical characteristics."1.27Distinctive plasma aldosterone, 18-hydroxycorticosterone, and 18-hydroxydeoxycorticosterone profile in the 21-, 17 alpha-, and 11 beta-hydroxylase deficiency types of congenital adrenal hyperplasia. ( Biglieri, EG; Kater, CE, 1983)
"The male pseudohermaphroditism resulted from deficient testosterone synthesis due to deficiency of 17 alpha-hydroxylase and 17,20 desmolase."1.27Male pseudohermaphroditism due to multiple defects in steroid-biosynthetic microsomal mixed-function oxidases. A new variant of congenital adrenal hyperplasia. ( Gautier, T; Imperato-McGinley, J; Peterson, RE; Shackleton, C, 1985)
"Light microscopy was compatible with Leydig cell tumor."1.26Cortisol production by testicular tumors in a patient with congenital adrenal hyperplasia (21-hydroxylase deficiency). ( Antonipillai, I; Franco-Saenz, R; Kropp, K; McCorquodale, M; Mulrow, PJ; Tan, SY, 1981)
"Corticosterone levels were 70 and 92 ng/ml and rose after ACTH (110 and 180 ng/ml)."1.26Dexamethasone-suppressible hypercorticosteronism in two 46,XX subjects with ambiguous genitalia and ovarian cysts. Partial defect of 17 alpha-hydroxylase or 17-20-desmolase. ( Canlorbe, P; Dehennin, L; Girard, F; Konopka, P; Merceron, RE; Roger, M; Seneze, J; Toublanc, JE, 1982)

Research

Studies (75)

TimeframeStudies, this research(%)All Research%
pre-199043 (57.33)18.7374
1990's12 (16.00)18.2507
2000's7 (9.33)29.6817
2010's10 (13.33)24.3611
2020's3 (4.00)2.80

Authors

AuthorsStudies
Sun, M1
Mueller, JW1
Gilligan, LC1
Taylor, AE1
Shaheen, F1
Noczyńska, A1
T'Sjoen, G1
Denvir, L1
Shenoy, S1
Fulton, P1
Cheetham, TD1
Gleeson, H1
Rahman, M1
Krone, NP1
Taylor, NF1
Shackleton, CHL1
Arlt, W1
Idkowiak, J1
Wang, M2
Milic, M1
Gericke, A1
Mercieca, K1
Liu, H1
Ruan, Y1
Jiang, S1
van Beers, T1
von Pein, HD1
Müller, MB1
Prokosch, V1
Seven Menevse, T1
Kendir Demirkol, Y1
Gurpinar Tosun, B1
Bayramoglu, E1
Yildiz, M1
Acar, S1
Erisen Karaca, S1
Orbak, Z1
Onder, A1
Sobu, E1
Anık, A1
Atay, Z1
Bugrul, F1
Derya Bulus, A1
Demir, K1
Dogan, D1
Cihan Emeksiz, H1
Kirmizibekmez, H1
Ozcan Murat, N1
Yaman, A1
Turan, S1
Bereket, A1
Guran, T1
Qin, F1
Liu, K1
Zhang, C1
Sun, X1
Zhang, Y1
Wu, Y1
Ma, W1
Wang, W1
Wu, X1
Qin, Y1
Zou, Y1
Zhou, X1
Jiang, X1
Wu, H1
Hui, R1
Wang, J1
Zhang, H1
Song, L1
Kulle, AE1
Riepe, FG1
Hedderich, J1
Sippell, WG3
Schmitz, J1
Niermeyer, L1
Holterhus, PM1
Auchus, RJ2
Nixon, M1
Mackenzie, SD1
Taylor, AI1
Homer, NZ1
Livingstone, DE1
Mouras, R1
Morgan, RA1
Mole, DJ1
Stimson, RH1
Reynolds, RM1
Elfick, AP1
Andrew, R1
Walker, BR1
Feldhaus, AL1
Anderson, K1
Dutzar, B1
Ojala, E1
McNeill, PD1
Fan, P1
Mulligan, J1
Marzolf, S1
Karasek, C1
Scalley-Kim, M1
Stewart, E1
Billgren, J1
Rubin, V1
Schneider, K1
Jurchen, D1
Snow, K1
Barnett, S1
Bengtsson, B1
Baker, B1
Latham, JA1
Allison, D1
Garcia-Martinez, LF1
Costa-Barbosa, FA1
Carvalho, VM1
Nakamura, OH1
Bachega, TA1
Vieira, JG2
Kater, CE5
Yamada, Y2
Sekihara, H2
Tsai, LC1
Beavo, JA1
Abrahams, L1
Semjonous, NM1
Guest, P1
Zielinska, A1
Hughes, B1
Lavery, GG1
Stewart, PM1
Kalani, A1
Bahtiyar, G1
Sacerdote, A1
Li, H1
Brochu, M1
Wang, SP1
Rochdi, L1
Côté, M1
Mitchell, G1
Gallo-Payet, N1
SPANAR, E1
ADAMEC, O1
KYSELA, J1
VILLEE, DB2
Perez, MS1
Benencia, H1
Frechtel, GD1
Esteban, EO1
Gil, MC1
Targovnik, HM1
Marquez, NB1
Wei, JQ2
Wei, JL2
Li, WC1
Bi, YS1
Wei, FC1
Paterson, JM1
Holmes, MC1
Kenyon, CJ1
Carter, R1
Mullins, JJ1
Seckl, JR1
Shih, MC1
Hsu, NC1
Huang, CC1
Wu, TS1
Lai, PY1
Chung, BC1
Bacchus, H1
Gordon, RC1
Kelsey, WM1
Franco-Saenz, R1
Antonipillai, I1
Tan, SY1
McCorquodale, M1
Kropp, K1
Mulrow, PJ1
Biglieri, EG8
Wajchenberg, BL1
Malerbi, DA1
Okada, H1
Leme, CE1
Tvedegaard, E1
Frederiksen, V1
Olgaard, K1
Nielsen, MD1
Starup, J1
Roger, M2
Merceron, RE1
Girard, F1
Canlorbe, P1
Dehennin, L1
Konopka, P1
Seneze, J1
Toublanc, JE1
de Gennes, JL1
Jambart, S1
Turpin, G1
Elkik, F1
Burstein, P1
Marsh, P1
Fennessey, P1
Betz, G2
D'Armiento, M1
Reda, G1
Kater, C1
Shackleton, CH3
Fennessey, PV1
Marsh, PG1
Orr, ER1
Burnstein, P1
Pardini, DP1
Watanabe, F1
Ryota, T1
Kobayashi, Y1
Mininberg, DT1
Levine, LS1
New, MI3
Brust, N1
Chang, B1
Hirai, J1
Nagase, M1
Ando, K1
Fujita, T1
Martin-Du Pan, RC1
Dahoun, S1
Stalberg, A1
Campana, A1
Dörr, HG1
Neuwinger, J1
Licht, P1
Munzer, B1
Sir-Petermann, T1
Siebzehnrübl, E1
Wildt, L1
Caron, KM1
Soo, SC1
Wetsel, WC1
Stocco, DM1
Clark, BJ1
Parker, KL1
Grumbach, MM1
Shaw, EB1
Bornstein, SR1
Tajima, T2
Eisenhofer, G1
Haidan, A1
Aguilera, G2
Okada, T1
Ma, XM1
Ramsey, W1
Bornstein, S1
Honour, JW3
Tourniaire, J1
Shackleton, HL1
Waldhäusl, W1
Herkner, K1
Nowotny, P1
Bratusch-Marrain, P1
Roitman, E1
West, CD1
Atcheson, JB1
Stanchfield, JB1
Rallison, ML1
Chavré, VJ1
Tyler, FH1
Maschler, I1
Weidenfeld, J1
Muller, A1
Slavin, S1
Shaefer, J1
Chowers, I1
Finkelstein, M1
Teofili, MT1
Vecchi, L1
Crigler, JF1
Toaff, ME1
Toaff, R1
Chayen, R1
Lucarelli, C1
Zhou, XT1
Wang, DQ1
Dai, WJ1
Li, S1
Li, SM1
Liu, RT1
Moreira, AC1
Leal, AM1
Castro, M1
Pang, S1
Yang, X1
Tissot, R1
Nino, M1
Manaligod, J1
Bullock, LP1
Mason, JI1
Chapman, TE1
Kraan, GP1
Nagel, GT1
Wolthers, BG1
Drayer, NM1
Peterson, RE2
Imperato-McGinley, J1
Gautier, T1
Shackleton, C1
Blau, N1
Zachmann, M2
Kempken, B1
Staudenmann, W1
Möhr, E1
Curtius, HC1
Doerr, HG1
Drop, SL1
Bidlingmaier, F1
Knorr, D1
Goldman, AS5
Winter, JS1
Scriba, PC1
Hacker, R1
Dieterle, P1
Kluge, F1
Hochheuser, W1
Schwarz, K1
Mallin, SR1
Miura, K1
Seaman, MP2
Neumann, F1
Mori, N1
Miyakawa, I1
Rappaport, R1
Cornu, G1
Royer, P1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Natural History Study of Patients With Excess Androgen[NCT00250159]3,000 participants (Anticipated)Observational2006-01-02Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for corticosterone and Congenital Adrenal Hyperplasia

ArticleYear
Steroid 17-hydroxylase and 17,20-lyase deficiencies, genetic and pharmacologic.
    The Journal of steroid biochemistry and molecular biology, 2017, Volume: 165, Issue:Pt A

    Topics: Abiraterone Acetate; Adrenal Hyperplasia, Congenital; Animals; Antihypertensive Agents; Corticostero

2017
The roles of cyclic nucleotide phosphodiesterases (PDEs) in steroidogenesis.
    Current opinion in pharmacology, 2011, Volume: 11, Issue:6

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adrenal Cortex; Adrenal Hy

2011
[Corticosterone].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 8

    Topics: ACTH Syndrome, Ectopic; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Biomarkers; Cortic

2005
The genetics, pathophysiology, and management of human deficiencies of P450c17.
    Endocrinology and metabolism clinics of North America, 2001, Volume: 30, Issue:1

    Topics: Adrenal Hyperplasia, Congenital; Corticosterone; Desoxycorticosterone; Humans; Mutation; Steroid 17-

2001
The adrenogenital syndrome.
    Clinics in perinatology, 1976, Volume: 3, Issue:1

    Topics: Adrenal Hyperplasia, Congenital; Corticosterone; Cortodoxone; Female; Glucocorticoids; Humans; Hydro

1976
[Adrenal cortex function tests and their interpretation].
    Nihon rinsho. Japanese journal of clinical medicine, 1969, Volume: 27, Issue:2

    Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Aldosterone; Androg

1969

Trials

1 trial available for corticosterone and Congenital Adrenal Hyperplasia

ArticleYear
A method for the simultaneous determination of the secretion rates of cortisol, 11-desoxycortisol, corticosterone, 11-desoxycorticosterone and aldosterone.
    The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:4

    Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adult; Aldosterone; Carbon Isotopes; Child; Child, Pres

1969

Other Studies

68 other studies available for corticosterone and Congenital Adrenal Hyperplasia

ArticleYear
The broad phenotypic spectrum of 17α-hydroxylase/17,20-lyase (CYP17A1) deficiency: a case series.
    European journal of endocrinology, 2021, Oct-11, Volume: 185, Issue:5

    Topics: Adolescent; Adrenal Hyperplasia, Congenital; Amenorrhea; Computer Simulation; Corticosterone; Failur

2021
Chronic social defeat stress causes retinal vascular dysfunction.
    Experimental eye research, 2021, Volume: 213

    Topics: Actins; Adrenal Hyperplasia, Congenital; Animals; Cell Survival; Chronic Disease; Corticosterone; Di

2021
Steroid Hormone Profiles and Molecular Diagnostic Tools in Pediatric Patients With non-CAH Primary Adrenal Insufficiency.
    The Journal of clinical endocrinology and metabolism, 2022, 04-19, Volume: 107, Issue:5

    Topics: Addison Disease; Adrenal Hyperplasia, Congenital; Child; Child, Preschool; Corticosterone; Cortisone

2022
Steroid metabolism gene variants and their genotype-phenotype correlations in Chinese early-onset hypertension patients.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2019, Volume: 42, Issue:10

    Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adult; Child; Corticosterone; G Protein-Coupled Inwardl

2019
LC-MS/MS based determination of basal- and ACTH-stimulated plasma concentrations of 11 steroid hormones: implications for detecting heterozygote CYP21A2 mutation carriers.
    European journal of endocrinology, 2015, Volume: 173, Issue:4

    Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormo

2015
ABCC1 confers tissue-specific sensitivity to cortisol versus corticosterone: A rationale for safer glucocorticoid replacement therapy.
    Science translational medicine, 2016, 08-17, Volume: 8, Issue:352

    Topics: Addison Disease; Adipose Tissue; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Anima

2016
ALD1613, a Novel Long-Acting Monoclonal Antibody to Control ACTH-Driven Pharmacology.
    Endocrinology, 2017, 01-01, Volume: 158, Issue:1

    Topics: Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Animals; Antibodies, Monoclonal; Antib

2017
Zona fasciculata 21-hydroxysteroids and precursor-to-product ratios in 21-hydroxylase deficiency: further characterization of classic and non-classic patients and heterozygote carriers.
    Journal of endocrinological investigation, 2011, Volume: 34, Issue:8

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Adult; Carrier State; Corticosterone;

2011
[Corticosterone, deoxycorticosterone].
    Nihon rinsho. Japanese journal of clinical medicine, 2010, Volume: 68 Suppl 7

    Topics: Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Corticosterone; Desoxycorticosterone; Fema

2010
Biomarkers of hypothalamic-pituitary-adrenal axis activity in mice lacking 11β-HSD1 and H6PDH.
    The Journal of endocrinology, 2012, Volume: 214, Issue:3

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adrenal Glands; Adrenal Hyperplasia, Congenital; Animal

2012
Ashwagandha root in the treatment of non-classical adrenal hyperplasia.
    BMJ case reports, 2012, Sep-17, Volume: 2012

    Topics: 17-alpha-Hydroxypregnenolone; Adrenal Hyperplasia, Congenital; Corticosterone; Diagnosis, Differenti

2012
Hormone-sensitive lipase deficiency in mice causes lipid storage in the adrenal cortex and impaired corticosterone response to corticotropin stimulation.
    Endocrinology, 2002, Volume: 143, Issue:9

    Topics: Adrenal Cortex; Adrenal Hyperplasia, Congenital; Adrenal Medulla; Adrenocorticotropic Hormone; Aldos

2002
[Diagnostic peculiarities of steroid hormone analysis in specific forms of the adrenogenital syndrome].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1963, Jan-15, Volume: 18

    Topics: 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Adrenogenital Syndrome; Corticosterone; Dexamethas

1963
EFFECTS OF SUBSTRATES AND COFACTORS ON STEROID SYNTHESIS IN HYPERPLASTIC ADRENALS.
    The Journal of clinical endocrinology and metabolism, 1964, Volume: 24

    Topics: Adolescent; Adrenal Cortex Hormones; Adrenal Glands; Adrenal Hyperplasia, Congenital; Carbon Isotope

1964
17alpha-hydroxylase deficiency : biochemical and molecular findings in two sisters and their family.
    Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology, 2004, Volume: 8, Issue:3

    Topics: Adrenal Hyperplasia, Congenital; Aldosterone; Amino Acid Sequence; Base Sequence; Corticosterone; Ex

2004
Genotyping of five chinese patients with 17alpha-hydroxylase deficiency diagnosed through high-performance liquid chromatography serum adrenal profile: identification of two novel CYP17 mutations.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:9

    Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adult; Base Sequence; China; Chromatography, High Press

2006
Liver-selective transgene rescue of hypothalamic-pituitary-adrenal axis dysfunction in 11beta-hydroxysteroid dehydrogenase type 1-deficient mice.
    Endocrinology, 2007, Volume: 148, Issue:3

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adrenal Glands; Adrenal Hyperplasia, Congenital; Animal

2007
Mutation of mouse Cyp11a1 promoter caused tissue-specific reduction of gene expression and blunted stress response without affecting reproduction.
    Molecular endocrinology (Baltimore, Md.), 2008, Volume: 22, Issue:4

    Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Animals; Binding Sites; Blotting, Western; Choleste

2008
A method for measurement of total 17-OH, 21-methyl steroids in the urine and its application to clinical problems.
    Metabolism: clinical and experimental, 1967, Volume: 16, Issue:2

    Topics: 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Hyperplasia, Con

1967
Pseudotumor cerebri in congenital adrenal hyperplasia.
    American journal of diseases of children (1960), 1967, Volume: 113, Issue:6

    Topics: Adrenal Cortex Hormones; Adrenal Hyperplasia, Congenital; Brain Diseases; Child; Corticosterone; Cor

1967
Cortisol production by testicular tumors in a patient with congenital adrenal hyperplasia (21-hydroxylase deficiency).
    The Journal of clinical endocrinology and metabolism, 1981, Volume: 53, Issue:1

    Topics: Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Chorionic Gonadotropin; Cortico

1981
The zonal origins of the mineralocorticoid hormones in the 21-hydroxylation deficiency of congenital adrenal hyperplasia.
    The Journal of clinical endocrinology and metabolism, 1981, Volume: 53, Issue:5

    Topics: 18-Hydroxycorticosterone; 18-Hydroxydesoxycorticosterone; Adolescent; Adrenal Cortex; Adrenal Hyperp

1981
Two cases of 17 alpha-hydroxylase deficiency--one combined with complete gonadal agenesis.
    Acta endocrinologica, 1981, Volume: 98, Issue:2

    Topics: 17-Ketosteroids; Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Al

1981
Dexamethasone-suppressible hypercorticosteronism in two 46,XX subjects with ambiguous genitalia and ovarian cysts. Partial defect of 17 alpha-hydroxylase or 17-20-desmolase.
    Hormone research, 1982, Volume: 16, Issue:1

    Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Aldosterone; Corticosteron

1982
17 alpha-hydroxylase deficiency syndrome associated with bilateral streak gonads and impaired development of Müllerian ducts derivatives. Report of a case.
    Acta endocrinologica, 1982, Volume: 100, Issue:1

    Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Aldosterone; Amenorrhea; C

1982
Male pseudohermaphroditism due to 17 alpha-hydroxylase deficiency: diagnosis by gas chromatography--mass spectrometry.
    Obstetrics and gynecology, 1983, Volume: 61, Issue:3 Suppl

    Topics: Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Corticosterone; Cross Reactions

1983
17 alpha-hydroxylase deficiency: mineralocorticoid hormone profiles in an affected family.
    The Journal of clinical endocrinology and metabolism, 1983, Volume: 56, Issue:4

    Topics: 18-Hydroxycorticosterone; 18-Hydroxydesoxycorticosterone; Adolescent; Adrenal Hyperplasia, Congenita

1983
Determination of steroid profiles in healthy and diseased states: identification and quantitation of a block of 17 alpha-hydroxylase.
    Clinica chimica acta; international journal of clinical chemistry, 1983, Mar-28, Volume: 129, Issue:1

    Topics: Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Androgens; Chorionic Gonadotrop

1983
Impaired mineralocorticoid hormone responses to adrenocorticotropin stimulation: additional characterization of heterozygosity for the 21-hydroxylase deficiency type of congenital adrenal hyperplasia.
    The Journal of clinical endocrinology and metabolism, 1983, Volume: 57, Issue:5

    Topics: 17-alpha-Hydroxyprogesterone; 18-Hydroxycorticosterone; 18-Hydroxydesoxycorticosterone; Adrenal Hype

1983
Enzyme immunoassay for serum 18-hydroxycorticosterone and its clinical application.
    Steroids, 1984, Volume: 43, Issue:5

    Topics: 18-Hydroxycorticosterone; ACTH Syndrome, Ectopic; Addison Disease; Adenoma; Adrenal Hyperplasia, Con

1984
Distinctive plasma aldosterone, 18-hydroxycorticosterone, and 18-hydroxydeoxycorticosterone profile in the 21-, 17 alpha-, and 11 beta-hydroxylase deficiency types of congenital adrenal hyperplasia.
    The American journal of medicine, 1983, Volume: 75, Issue:1

    Topics: 18-Hydroxycorticosterone; 18-Hydroxydesoxycorticosterone; Adolescent; Adrenal Hyperplasia, Congenita

1983
Current concepts in congenital adrenal hyperplasia.
    Pathology annual, 1982, Volume: 17 Pt 2

    Topics: 17-Hydroxycorticosteroids; Adrenal Hyperplasia, Congenital; Child, Preschool; Cholesterol Side-Chain

1982
The unique patterns of plasma aldosterone and 18-hydroxycorticosterone concentrations in the 17 alpha-hydroxylase deficiency syndrome.
    The Journal of clinical endocrinology and metabolism, 1982, Volume: 55, Issue:2

    Topics: 18-Hydroxycorticosterone; 18-Hydroxydesoxycorticosterone; Adrenal Hyperplasia, Congenital; Adult; Al

1982
Salt sensitivity of blood pressure in patients with 17 alpha-hydroxylase deficiency.
    American journal of hypertension, 1994, Volume: 7, Issue:11

    Topics: Adrenal Hyperplasia, Congenital; Adult; Blood Pressure; Corticosterone; Desoxycorticosterone; Humans

1994
[Primary amenorrhea and arterial hypertension in a case of 17 alpha-hydroxylase deficiency].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 1994, Volume: 23, Issue:2

    Topics: Adrenal Hyperplasia, Congenital; Adult; Aldosterone; Amenorrhea; Corticosterone; Desoxycorticosteron

1994
Prenatal dexamethasone treatment in pregnancies at risk for congenital adrenal hyperplasia due to 21-hydroxylase deficiency: effect on midgestational amniotic fluid steroid levels.
    The Journal of clinical endocrinology and metabolism, 1993, Volume: 76, Issue:1

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Aldosterone; Amniocentesis; Amniotic

1993
Substitution with testosterone as aromatizable substrate for induction of follicular maturation, estradiol production and ovulation in a patient with 17 alpha-hydroxylase deficiency.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 1996, Volume: 104, Issue:5

    Topics: Adrenal Hyperplasia, Congenital; Adult; Corticosterone; Estradiol; Female; Humans; Ovarian Follicle;

1996
Targeted disruption of the mouse gene encoding steroidogenic acute regulatory protein provides insights into congenital lipoid adrenal hyperplasia.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, Oct-14, Volume: 94, Issue:21

    Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormon

1997
Further studies on the treatment of congenital adrenal hyperplasia with cortisone: IV. Effect of cortisone and compound B in infants with disturbed electrolyte metabolism, by John F. Crigler Jr, MD, Samuel H. Silverman, MD, and Lawson Wilkins, MD, Pediatr
    Pediatrics, 1998, Volume: 102, Issue:1 Pt 2

    Topics: Adrenal Hyperplasia, Congenital; Corticosterone; Cortisone; History, 20th Century; Humans; Infant

1998
Adrenomedullary function is severely impaired in 21-hydroxylase-deficient mice.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1999, Volume: 13, Issue:10

    Topics: Adrenal Hyperplasia, Congenital; Adrenal Medulla; Animals; Base Sequence; Catecholamines; Chromaffin

1999
Restoration of adrenal steroidogenesis by adenovirus-mediated transfer of human cytochromeP450 21-hydroxylase into the adrenal gland of21-hydroxylase-deficient mice.
    Gene therapy, 1999, Volume: 6, Issue:11

    Topics: Adenoviridae; Adrenal Glands; Adrenal Hyperplasia, Congenital; Animals; Corticosterone; Female; Gene

1999
Mechanisms establishing the mineralocorticoid hormone patterns in the 17 alpha-hydroxylase deficiency syndrome.
    Journal of steroid biochemistry, 1979, Volume: 11, Issue:1B

    Topics: 18-Hydroxycorticosterone; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Aldos

1979
Urinary steroid excretion in 17 alpha-hydroxylase deficiency.
    Journal of steroid biochemistry, 1978, Volume: 9, Issue:6

    Topics: 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Corticosterone; Desoxycorticosterone; Humans; Hydr

1978
Differences in metabolism of corticosterone by the newborn and adult human.
    Biochemical Society transactions, 1978, Volume: 6, Issue:4

    Topics: Adrenal Hyperplasia, Congenital; Adult; Aldosterone; Corticosterone; Humans; Infant, Newborn; Steroi

1978
Combined 17 alpha- and 18-hydroxylase deficiency associated with complete male pseudohermaphroditism and hypoaldosteronism.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 46, Issue:2

    Topics: Adrenal Hyperplasia, Congenital; Aldosterone; Corticosterone; Desoxycorticosterone; Disorders of Sex

1978
Metabolism of radiolabeled corticosterone in an adult with the 17 alpha-hydroxylase deficiency syndrome.
    The Journal of clinical endocrinology and metabolism, 1979, Volume: 48, Issue:6

    Topics: Adrenal Hyperplasia, Congenital; Adult; Chromatography, Gas; Corticosterone; Female; Humans; Mass Sp

1979
Multiple or single 21-hydroxylases in congenital adrenal hyperplasia?
    Journal of steroid biochemistry, 1979, Volume: 11, Issue:4

    Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adult; Child; Circadian Rhythm; Corticosterone; Female;

1979
A case of adrenogenital syndrome with aberrant 11beta-hydroxylation.
    Acta endocrinologica, 1977, Volume: 85, Issue:4

    Topics: 17-Ketosteroids; Adolescent; Adrenal Hyperplasia, Congenital; Amenorrhea; Corticosterone; Female; Hi

1977
[Main enzymatic disorders of the adrenal cortex and their therapeutic possibilities].
    La Clinica terapeutica, 1978, Jul-31, Volume: 86, Issue:2

    Topics: Adrenal Cortex; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Corticosterone; Femal

1978
Congenital adrenal hyperplasia caused by 11 beta-hydroxylase deficiency with onset of symptoms after one spontaneous pregnancy.
    American journal of obstetrics and gynecology, 1975, Jan-15, Volume: 121, Issue:2

    Topics: 17-Ketosteroids; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adult; Androgens; Chromatography,

1975
Serum steroid hormonal profiles by reversed-phase liquid chromatography in patients with 17-hydroxylase deficiency and in an affected family.
    Clinical chemistry, 1992, Volume: 38, Issue:1

    Topics: Adolescent; Adrenal Cortex Hormones; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; A

1992
Adrenocorticotropin-corticosterone relationship during dexamethasone therapy in 17 alpha-hydroxylase deficiency.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1992, Volume: 24, Issue:7

    Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Aldosterone; Corticosteron

1992
Inherited congenital adrenal hyperplasia in the rabbit: absent cholesterol side-chain cleavage cytochrome P450 gene expression.
    Endocrinology, 1992, Volume: 131, Issue:1

    Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Animals; Blotting, Northern; Cholesterol Side-Chain

1992
Measurement of the cortisol production rate in two sisters with 17 alpha-hydroxylase deficiency using [1,2,3,4-13C]cortisol and isotope dilution mass spectrometry.
    The Journal of steroid biochemistry and molecular biology, 1991, Volume: 38, Issue:4

    Topics: Adrenal Hyperplasia, Congenital; Carbon Isotopes; Child; Child, Preschool; Chromatography, High Pres

1991
Male pseudohermaphroditism due to multiple defects in steroid-biosynthetic microsomal mixed-function oxidases. A new variant of congenital adrenal hyperplasia.
    The New England journal of medicine, 1985, Nov-07, Volume: 313, Issue:19

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; 18-Hydroxycorticosterone; 18-Hydroxydesoxycorticosterone

1985
Identification of new steroids in patients with 17 alpha-hydroxylase deficiency by capillary gas chromatography/mass spectrometry.
    Biomedical & environmental mass spectrometry, 1987, Volume: 14, Issue:11

    Topics: Adrenal Hyperplasia, Congenital; Corticosterone; Female; Gas Chromatography-Mass Spectrometry; Human

1987
[Hirsutism and light forms of congenital adrenogenital syndrome with 21- and 11-beta hydroxylase defect].
    Schweizerische medizinische Wochenschrift, 1986, Mar-29, Volume: 116, Issue:13

    Topics: Adolescent; Adrenal Hyperplasia, Congenital; Aldosterone; Androgens; Child; Child, Preschool; Cortic

1986
Evidence of 11 beta-hydroxylase deficiency in childhood adrenocortical tumors. The plasma corticosterone/11-deoxycorticosterone ratio as a possible marker for malignancy.
    Cancer, 1987, Oct-01, Volume: 60, Issue:7

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Hyperplasia, Congenital; Carcinoma; Child; Child, Prescho

1987
Activities of various steroidogenic enzymes in two forms of experimental adrenal hyperplasia.
    The Journal of clinical endocrinology and metabolism, 1967, Volume: 27, Issue:12

    Topics: Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Animals; Corticosterone; Female; Fluor

1967
[ACTH determination in the plasma from the cranial bulb of the jugular vein].
    Klinische Wochenschrift, 1966, Dec-15, Volume: 44, Issue:24

    Topics: Addison Disease; Adolescent; Adrenal Hyperplasia, Congenital; Adrenal Insufficiency; Adrenalectomy;

1966
Congenital adrenal hyperplasia secondary to 17-hydroxylase deficiency. Two sisters with amenorrhea, hypokalemia, hypertension, and cystic ovaries.
    Annals of internal medicine, 1969, Volume: 70, Issue:1

    Topics: Adolescent; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Amenorrhea

1969
Secretion rates of cortisol and aldosterone precursors in various forms of congenital adrenal hyperplasia.
    The Journal of clinical endocrinology and metabolism, 1970, Volume: 30, Issue:3

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hor

1970
Prevention of Mammary gland defects in experimental congenital adrenal hyperplasia due to inhibition to 3 beta-hydroxysteroid dehydrogenase in rats.
    Endocrinology, 1970, Volume: 86, Issue:5

    Topics: Abnormalities, Drug-Induced; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Ho

1970
Experimental model of congenital adrenal cortical hyperplasia produced in utero with an inhibitor of 11-beta-steroid hydroxylase.
    The Journal of clinical endocrinology and metabolism, 1967, Volume: 27, Issue:10

    Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Animals; Corticosteron

1967
Congenital adrenogenital syndrome and successful pregnancy. Report of a case.
    Obstetrics and gynecology, 1970, Volume: 35, Issue:3

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Gland Diseases; Adrenal Hyperplasia,

1970
Experimental congenital lipoid adrenal hyperplasia: prevention of anatomic defects produced by aminoglutethimide.
    Endocrinology, 1970, Volume: 87, Issue:5

    Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Aminoglutethimide; Aniline Compounds; Animals; Anti

1970
Statural growth in congenital adrenal hyperplasia treated with hydrocortisone.
    The Journal of pediatrics, 1968, Volume: 73, Issue:5

    Topics: Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Body Height; Bone Development; Child,

1968
Prevention of anatomic defects in congenital adrenal hyperplasia produced by estradiol-17-beta in rats.
    The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:1

    Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Animals; Clitoris; Corticosterone; Estrogen Antagon

1969