corticosterone has been researched along with Cocaine Abuse in 46 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this scenario, the permanent effects of cocaine exposure during adolescence on anxiety levels and stress responsivity, which may result in behavioral phenotypes prone to addiction, are now starting to be unveiled." | 7.80 | Long-term effects of chronic cocaine exposure throughout adolescence on anxiety and stress responsivity in a Wistar rat model. ( Alves, CJ; de Sousa, L; Magalhães, A; Melo, P; Monteiro, PR; Summavielle, T; Tavares, MA, 2014) |
| " We assessed corticosterone, proopiomelanocortin (POMC), β-endorphin, CART 55-102 levels in plasma (by ELISA), along with mRNA levels for D2 dopaminergic receptor (D2R), κ-receptor (KOR), orexin 1 receptor (OX1R), CART 55-102, and potential markers of cocaine abuse: miRNA-124 and miRNA-137 levels in the PFC (by PCR)." | 4.31 | Molecular pattern of a decrease in the rewarding effect of cocaine after an escalating-dose drug regimen. ( Bednarska-Makaruk, M; Gawryluk, A; Kołosowska, K; Lehner, M; Liguz-Lęcznar, M; Maciejak, P; Skórzewska, A; Sobolewska, A; Tomczuk, F; Turzyńska, D; Wisłowska-Stanek, A, 2023) |
| " In this scenario, the permanent effects of cocaine exposure during adolescence on anxiety levels and stress responsivity, which may result in behavioral phenotypes prone to addiction, are now starting to be unveiled." | 3.80 | Long-term effects of chronic cocaine exposure throughout adolescence on anxiety and stress responsivity in a Wistar rat model. ( Alves, CJ; de Sousa, L; Magalhães, A; Melo, P; Monteiro, PR; Summavielle, T; Tavares, MA, 2014) |
| " Anxiety was assessed on the elevated plus maze (EPM) both prior to and following the administration of the anxiolytic drug diazepam, and by blood corticosterone levels following forced novelty exposure." | 3.77 | High impulsivity predicting vulnerability to cocaine addiction in rats: some relationship with novelty preference but not novelty reactivity, anxiety or stress. ( Belin, D; Caprioli, D; Dalley, JW; Everitt, BJ; Mar, A; Molander, AC; Moreno, M; Norbury, A; Robbins, TW; Steventon, S; Theobald, DE, 2011) |
| " Further, EPM exposure elicited higher anxiety levels and enhanced plasma corticosterone secretion in HG rats." | 3.71 | Enhanced motivation to self-administer cocaine is predicted by self-grooming behaviour and relates to dopamine release in the rat medial prefrontal cortex and amygdala. ( Binnekade, R; de Vries, TJ; Homberg, JR; Raasø, HS; Schoffelmeer, AN; van den Akker, M; Wardeh, G, 2002) |
| "Binge eating is a specific form of overeating characterized by intermittent, excessive eating." | 1.48 | Housing conditions modulate the reinforcing properties of cocaine in adolescent mice that binge on fat. ( Aguilar, MA; Blanco-Gandía, MC; Miñarro, J; Montagud-Romero, S; Rodríguez-Arias, M, 2018) |
| "The key problem in treating cocaine addiction is the maintenance of a drug-free state as negative emotional symptoms during abstinence often trigger relapse." | 1.43 | Cocaine abstinence induces emotional impairment and brain region-specific upregulation of the oxytocin receptor binding. ( Bailey, A; Georgiou, P; Hourani, S; Kitchen, I; Zanos, P, 2016) |
| "Corticosterone levels were significantly different at the end of the 15-min session, but not following the 2-h session." | 1.39 | Combinations of oxazepam and metyrapone attenuate cocaine and methamphetamine cue reactivity. ( Cornett, EM; Goeders, NE; Guerin, GF; Keller, CM, 2013) |
| "Cocaine addiction is known to impair immune system function, but the effects of repeated treatment with cocaine in a self-administration model, its withdrawal as well as reinstatement of cocaine-seeking behavior on cell-mediated immunity are not well known." | 1.35 | Immunosuppression induced by a conditioned stimulus associated with cocaine self-administration. ( Basta-Kaim, A; Budziszewska, B; Filip, M; Jaworska-Feil, L; Kubera, M; Lason, W; Leskiewicz, M; Machowska, A; Przegalinski, E; Regulska, M; Wydra, K, 2008) |
| "One approach for studying cocaine addiction has been to permit escalating patterns of self-administration (SA) by rats by prolonging daily drug availability." | 1.32 | Neuroendocrine alterations in a high-dose, extended-access rat self-administration model of escalating cocaine use. ( Ho, A; Kreek, MJ; Mantsch, JR; Mathieu-Kia, AM; Yuferov, V, 2003) |
| "Pretreatment with ketoconazole reversed the conditioned reinforcer-induced reinstatement of extinguished cocaine-seeking behavior and also attenuated the conditioned increases in plasma corticosterone observed during reinstatement." | 1.31 | Potential role for the hypothalamo-pituitary-adrenal axis in the conditioned reinforcer-induced reinstatement of extinguished cocaine seeking in rats. ( Clampitt, DM; Goeders, NE, 2002) |
| "Ketoconazole is an FDA-approved antifungal agent that also blocks the synthesis of adrenocorticosteroids and functions as a glucocorticoid receptor antagonist." | 1.30 | Ketoconazole does not block cocaine discrimination or the cocaine-induced reinstatement of cocaine-seeking behavior. ( Goeders, NE; Mantsch, JR, 1999) |
| "Pretreatment with ketoconazole (25 mg/kg, i." | 1.30 | Ketoconazole reduces low dose cocaine self-administration in rats. ( Goeders, NE; Guerin, GF; Peltier, RL, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (8.70) | 18.2507 |
| 2000's | 23 (50.00) | 29.6817 |
| 2010's | 18 (39.13) | 24.3611 |
| 2020's | 1 (2.17) | 2.80 |
| Authors | Studies |
|---|---|
| Kołosowska, K | 1 |
| Lehner, M | 1 |
| Skórzewska, A | 1 |
| Gawryluk, A | 1 |
| Tomczuk, F | 1 |
| Sobolewska, A | 1 |
| Turzyńska, D | 1 |
| Liguz-Lęcznar, M | 1 |
| Bednarska-Makaruk, M | 1 |
| Maciejak, P | 1 |
| Wisłowska-Stanek, A | 1 |
| Keller, CM | 2 |
| Goeders, NE | 7 |
| Stringfield, SJ | 1 |
| Higginbotham, JA | 1 |
| Wang, R | 1 |
| Berger, AL | 1 |
| McLaughlin, RJ | 1 |
| Fuchs, RA | 1 |
| Pizzimenti, CL | 1 |
| Navis, TM | 1 |
| Lattal, KM | 1 |
| Blanco-Gandía, MC | 1 |
| Montagud-Romero, S | 3 |
| Aguilar, MA | 2 |
| Miñarro, J | 2 |
| Rodríguez-Arias, M | 2 |
| Robison, LS | 1 |
| Alessi, L | 1 |
| Thanos, PK | 1 |
| You, ZB | 1 |
| Wang, B | 1 |
| Gardner, EL | 1 |
| Wise, RA | 1 |
| Cornett, EM | 1 |
| Guerin, GF | 4 |
| Alves, CJ | 1 |
| Magalhães, A | 1 |
| Melo, P | 1 |
| de Sousa, L | 1 |
| Tavares, MA | 1 |
| Monteiro, PR | 1 |
| Summavielle, T | 1 |
| Zhou, Y | 3 |
| Kreek, MJ | 6 |
| Hofford, RS | 1 |
| Prendergast, MA | 1 |
| Bardo, MT | 1 |
| Maldonado, C | 1 |
| Manzanedo, C | 1 |
| Wong, WC | 1 |
| Marinelli, M | 1 |
| Manvich, DF | 1 |
| Stowe, TA | 1 |
| Godfrey, JR | 1 |
| Weinshenker, D | 1 |
| Hadad, NA | 1 |
| Wu, L | 1 |
| Hiller, H | 1 |
| Krause, EG | 1 |
| Schwendt, M | 1 |
| Knackstedt, LA | 1 |
| Boyson, CO | 1 |
| Holly, EN | 1 |
| Burke, AR | 1 |
| DeBold, JF | 1 |
| Miczek, KA | 2 |
| Georgiou, P | 1 |
| Zanos, P | 1 |
| Hourani, S | 1 |
| Kitchen, I | 2 |
| Bailey, A | 2 |
| Maćkowiak, M | 1 |
| Grzegorzewska, M | 1 |
| Budziszewska, B | 2 |
| Chocyk, A | 1 |
| Hess, G | 1 |
| Wedzony, K | 1 |
| Cleck, JN | 1 |
| Ecke, LE | 1 |
| Blendy, JA | 1 |
| Kubera, M | 1 |
| Filip, M | 1 |
| Basta-Kaim, A | 1 |
| Wydra, K | 1 |
| Leskiewicz, M | 1 |
| Regulska, M | 1 |
| Jaworska-Feil, L | 1 |
| Przegalinski, E | 1 |
| Machowska, A | 1 |
| Lason, W | 1 |
| Vendruscolo, LF | 1 |
| Vendruscolo, JC | 1 |
| Terenina, E | 1 |
| Ramos, A | 1 |
| Takahashi, RN | 1 |
| Mormède, P | 1 |
| Molander, AC | 1 |
| Mar, A | 1 |
| Norbury, A | 1 |
| Steventon, S | 1 |
| Moreno, M | 1 |
| Caprioli, D | 1 |
| Theobald, DE | 1 |
| Belin, D | 1 |
| Everitt, BJ | 1 |
| Robbins, TW | 1 |
| Dalley, JW | 1 |
| Thiel, KJ | 1 |
| Painter, MR | 1 |
| Pentkowski, NS | 1 |
| Mitroi, D | 1 |
| Crawford, CA | 1 |
| Neisewander, JL | 1 |
| Spangler, R | 2 |
| Ho, A | 4 |
| Mantsch, JR | 6 |
| Yuferov, V | 1 |
| Mathieu-Kia, AM | 1 |
| Perrotti, LI | 1 |
| Lu, D | 1 |
| Niyomachai, T | 1 |
| Cornejo, S | 1 |
| Russo, SJ | 1 |
| Jenab, S | 1 |
| Quiñones-Jenab, V | 2 |
| Baumann, MH | 1 |
| Milchanowski, AB | 1 |
| Rothman, RB | 1 |
| Katz, ES | 4 |
| de Jong, IE | 1 |
| Oitzl, MS | 1 |
| de Kloet, ER | 1 |
| Taves, S | 1 |
| Khan, T | 1 |
| Sajan, T | 1 |
| Tang, LC | 2 |
| Cullinan, WE | 2 |
| Ziegler, DR | 2 |
| Tessari, M | 1 |
| Catalano, A | 1 |
| Pellitteri, M | 1 |
| Di Francesco, C | 1 |
| Marini, F | 1 |
| Gerrard, PA | 1 |
| Heidbreder, CA | 1 |
| Melotto, S | 1 |
| Yoo, JH | 1 |
| Racz, I | 1 |
| Zimmer, A | 1 |
| Baker, DA | 2 |
| Serge, JP | 1 |
| Hoks, MA | 2 |
| Francis, DM | 1 |
| Sarnyai, Z | 1 |
| Dhabhar, FS | 1 |
| McEwen, BS | 1 |
| Schlussman, SD | 2 |
| Fienberg, AA | 1 |
| Greengard, P | 1 |
| Krey, LC | 1 |
| Antelman, SM | 1 |
| Caggiula, AR | 1 |
| Edwards, DJ | 1 |
| Gershon, S | 1 |
| Kucinski, BJ | 1 |
| Kiss, S | 1 |
| Kocan, D | 1 |
| Peltier, RL | 2 |
| Kosten, TA | 1 |
| Miserendino, MJ | 1 |
| Kehoe, P | 1 |
| Dorairaj, N | 1 |
| Covington, HE | 1 |
| Clampitt, DM | 1 |
| Homberg, JR | 1 |
| van den Akker, M | 1 |
| Raasø, HS | 1 |
| Wardeh, G | 1 |
| Binnekade, R | 1 |
| Schoffelmeer, AN | 1 |
| de Vries, TJ | 1 |
46 other studies available for corticosterone and Cocaine Abuse
| Article | Year |
|---|---|
Molecular pattern of a decrease in the rewarding effect of cocaine after an escalating-dose drug regimen.
Topics: Animals; beta-Endorphin; Cocaine; Cocaine-Related Disorders; Corticosterone; MicroRNAs; Pro-Opiomela | 2023 |
Lack of effect of the combination of metyrapone and oxazepam on brain dopamine.
Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Corticosterone; Dopamine; Dopamine Uptake Inhibi | 2019 |
Role of glucocorticoid receptor-mediated mechanisms in cocaine memory enhancement.
Topics: Animals; Basolateral Nuclear Complex; Cocaine; Cocaine-Related Disorders; Corticosterone; Dose-Respo | 2017 |
Persistent effects of acute stress on fear and drug-seeking in a novel model of the comorbidity between post-traumatic stress disorder and addiction.
Topics: Animals; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Conditioning, Operan | 2017 |
Housing conditions modulate the reinforcing properties of cocaine in adolescent mice that binge on fat.
Topics: Animals; Animals, Outbred Strains; Anxiety; Bulimia; Cocaine; Cocaine-Related Disorders; Conditionin | 2018 |
Chronic forced exercise inhibits stress-induced reinstatement of cocaine conditioned place preference.
Topics: Animals; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Conditioning, Psycho | 2018 |
Cocaine and cocaine expectancy increase growth hormone, ghrelin, GLP-1, IGF-1, adiponectin, and corticosterone while decreasing leptin, insulin, GIP, and prolactin.
Topics: Adiponectin; Animals; Cocaine; Cocaine-Related Disorders; Corticosterone; Disease Models, Animal; Dr | 2019 |
Combinations of oxazepam and metyrapone attenuate cocaine and methamphetamine cue reactivity.
Topics: Amphetamine-Related Disorders; Analysis of Variance; Animals; Central Nervous System Stimulants; Coc | 2013 |
Long-term effects of chronic cocaine exposure throughout adolescence on anxiety and stress responsivity in a Wistar rat model.
Topics: Animals; Anxiety; Body Weight; Brain; Cocaine; Cocaine-Related Disorders; Corticosterone; Dopamine; | 2014 |
Persistent increases in rat hypothalamic POMC gene expression following chronic withdrawal from chronic "binge" pattern escalating-dose, but not steady-dose, cocaine.
Topics: Amygdala; Animals; Body Weight; Cocaine; Cocaine-Related Disorders; Corticosterone; Dopamine Uptake | 2015 |
Pharmacological manipulation of glucocorticoid receptors differentially affects cocaine self-administration in environmentally enriched and isolated rats.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Corticosterone; Dopamine Uptake Inhibitors; Hormone Ant | 2015 |
Acute social defeat stress increases the conditioned rewarding effects of cocaine in adult but not in adolescent mice.
Topics: Aggression; Aging; Agonistic Behavior; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Op | 2015 |
Adolescent-onset of cocaine use is associated with heightened stress-induced reinstatement of cocaine seeking.
Topics: Age of Onset; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Psycholog | 2016 |
A Method for Psychosocial Stress-Induced Reinstatement of Cocaine Seeking in Rats.
Topics: Adaptation, Psychological; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corti | 2016 |
Conditioned stress prevents cue-primed cocaine reinstatement only in stress-responsive rats.
Topics: Amygdala; Animals; Cocaine; Cocaine-Related Disorders; Corticosterone; Corticotropin-Releasing Hormo | 2016 |
Maladaptive choices by defeated rats: link between rapid approach to social threat and escalated cocaine self-administration.
Topics: Aggression; Animals; Behavior, Animal; Choice Behavior; Cocaine; Cocaine-Related Disorders; Corticos | 2016 |
Cocaine abstinence induces emotional impairment and brain region-specific upregulation of the oxytocin receptor binding.
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Corticosterone; Emotions; Hypothalamo | 2016 |
Cocaine decreases the expression of PSA-NCAM protein and attenuates long-term potentiation via glucocorticoid receptors in the rat dentate gyrus.
Topics: Animals; Bromodeoxyuridine; Cell Count; Cell Proliferation; Cocaine; Cocaine-Related Disorders; Cort | 2008 |
Endocrine and gene expression changes following forced swim stress exposure during cocaine abstinence in mice.
Topics: Acetylation; Amygdala; Anesthetics, Local; Animals; Anxiety; Behavior, Animal; Brain-Derived Neurotr | 2008 |
Effects of the combination of metyrapone and oxazepam on cocaine and food self-administration in rats.
Topics: Animals; Cocaine-Related Disorders; Conditioning, Operant; Corticosterone; Dose-Response Relationshi | 2008 |
Immunosuppression induced by a conditioned stimulus associated with cocaine self-administration.
Topics: Animals; Cell Proliferation; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corticostero | 2008 |
Marker-assisted dissection of genetic influences on motor and neuroendocrine sensitization to cocaine in rats.
Topics: Animals; Behavior, Animal; Biomarkers; Brain Chemistry; Cocaine; Cocaine-Related Disorders; Corticos | 2009 |
High impulsivity predicting vulnerability to cocaine addiction in rats: some relationship with novelty preference but not novelty reactivity, anxiety or stress.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Cocaine-Related Disorders; Conditioning, Operant; Corticoster | 2011 |
Environmental enrichment counters cocaine abstinence-induced stress and brain reactivity to cocaine cues but fails to prevent the incubation effect.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cocaine; Cocaine-Related Disorders; Conditioning, Operan | 2012 |
Increased CRH mRNA levels in the rat amygdala during short-term withdrawal from chronic 'binge' cocaine.
Topics: Amygdala; Animals; Brain Stem; Chronic Disease; Cocaine; Cocaine-Related Disorders; Corticosterone; | 2003 |
Neuroendocrine alterations in a high-dose, extended-access rat self-administration model of escalating cocaine use.
Topics: Adrenal Glands; Animals; Circadian Rhythm; Cocaine; Cocaine-Related Disorders; Corticosterone; Drug | 2003 |
Temporal effects of estrogen and progesterone on behavioral and endocrinological responses to acute cocaine administration.
Topics: Acute Disease; Animals; Behavior; Cocaine; Cocaine-Related Disorders; Corticosterone; Endocrine Syst | 2003 |
Evidence for alterations in alpha2-adrenergic receptor sensitivity in rats exposed to repeated cocaine administration.
Topics: Adrenergic alpha-Agonists; Animals; Brain; Clonidine; Cocaine; Cocaine-Related Disorders; Corticoste | 2004 |
Elevation of glucocorticoids is necessary but not sufficient for the escalation of cocaine self-administration by chronic electric footshock stress in rats.
Topics: Animals; Behavior, Addictive; Behavior, Animal; Chronic Disease; Cocaine; Cocaine-Related Disorders; | 2007 |
Adrenalectomy prevents behavioural sensitisation of mice to cocaine in a genotype-dependent manner.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Animals; Behavior, Animal; Body Weight; Cocaine; Cocaine | 2007 |
Restraint-induced corticosterone secretion and hypothalamic CRH mRNA expression are augmented during acute withdrawal from chronic cocaine administration.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Corticosterone; Corticotropin-Releasing Hormone; Dopami | 2007 |
Correlation between serum ghrelin levels and cocaine-seeking behaviour triggered by cocaine-associated conditioned stimuli in rats.
Topics: Animals; Cocaine-Related Disorders; Conditioning, Classical; Corticosterone; Cues; Ghrelin; Injectio | 2007 |
Preprodynorphin mediates locomotion and D2 dopamine and mu-opioid receptor changes induced by chronic 'binge' cocaine administration.
Topics: Analgesics, Opioid; Animals; Binding, Competitive; Cocaine; Cocaine-Related Disorders; Corticosteron | 2007 |
Surgical adrenalectomy with diurnal corticosterone replacement slows escalation and prevents the augmentation of cocaine-induced reinstatement in rats self-administering cocaine under long-access conditions.
Topics: Adrenalectomy; Analysis of Variance; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; | 2008 |
Daily cocaine self-administration under long-access conditions augments restraint-induced increases in plasma corticosterone and impairs glucocorticoid receptor-mediated negative feedback in rats.
Topics: Animals; Brain; Chronic Disease; Cocaine; Cocaine-Related Disorders; Corticosterone; Corticotropin-R | 2007 |
Neuroendocrine-related effects of long-term, 'binge' cocaine administration: diminished individual differences in stress-induced corticosterone response.
Topics: Analysis of Variance; Animals; Cocaine-Related Disorders; Corticosterone; Drug Administration Schedu | 1998 |
Ketoconazole does not block cocaine discrimination or the cocaine-induced reinstatement of cocaine-seeking behavior.
Topics: Animals; Antifungal Agents; Catheterization; Cocaine; Cocaine-Related Disorders; Corticosterone; Dis | 1999 |
Effects of chronic 'Binge' cocaine administration on plasma ACTH and corticosterone levels in mice deficient in DARPP-32.
Topics: Adrenocorticotropic Hormone; Animals; Chronic Disease; Cocaine; Cocaine-Related Disorders; Corticost | 1999 |
Chronic 'binge' pattern cocaine alters the neuroendocrine profile of pregnant rats.
Topics: Animals; Cocaine-Related Disorders; Corticosterone; Female; Gestational Age; Nesting Behavior; Pregn | 2000 |
Long-term oscillation of corticosterone following intermittent cocaine.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Corticosterone; Dopamine Uptake Inhibitors; Drug Admini | 2000 |
Ketoconazole reduces low dose cocaine self-administration in rats.
Topics: Animals; Arousal; Cocaine-Related Disorders; Corticosterone; Dose-Response Relationship, Drug; Hypot | 1998 |
Enhanced acquisition of cocaine self-administration in adult rats with neonatal isolation stress experience.
Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning | 2000 |
Effects of saline substitution on responding and plasma corticosterone in rats trained to self-administer different doses of cocaine.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corticosterone; Dopamine Uptake | 2001 |
Repeated social-defeat stress, cocaine or morphine. Effects on behavioral sensitization and intravenous cocaine self-administration "binges".
Topics: Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Co | 2001 |
Potential role for the hypothalamo-pituitary-adrenal axis in the conditioned reinforcer-induced reinstatement of extinguished cocaine seeking in rats.
Topics: Analysis of Variance; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corticoste | 2002 |
Enhanced motivation to self-administer cocaine is predicted by self-grooming behaviour and relates to dopamine release in the rat medial prefrontal cortex and amygdala.
Topics: Amygdala; Animals; Anxiety; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cortico | 2002 |