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corticosterone and Brain Ischemia

corticosterone has been researched along with Brain Ischemia in 38 studies

Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.

Research Excerpts

ExcerptRelevanceReference
" In rodents, global cerebral ischemia leads to selective CA1 neuronal damage, spatial memory impairments, lasting changes in corticosterone (CORT) secretion, and increased neurogenesis."7.83Dose-related effects of chronic resveratrol administration on neurogenesis, angiogenesis, and corticosterone secretion are associated with improved spatial memory retention following global cerebral ischemia. ( Girbovan, C; Kent, P; Merali, Z; Plamondon, H, 2016)
"Under cerebral ischemia or aortic stenosis, changes in plasma and adrenal corticosterone (CS) levels before and after cardiac arrest-preceding type (CPT) and apnea-preceding type (APT) sudden death were examined to determine the response of the hypophyseal adrenocortical system in Wistar rats."7.67[Experimental studies on stress hormones at the time of sudden death (II)--Differences in adrenocortical hormone levels of cardiac arrest-preceding type and apnea preceding type sudden death under cerebral ischemia or aortic stenosis]. ( Douge, K; Ming-Chang, T; Tsunoda, K; Watanabe, T, 1989)
"the glucose paradox of cerebral ischemia, is a well-established phenomenon that has prompted clinicians around the world to closely monitor and control blood glucose levels in surgical cases at high risk for ischemic episodes."5.32The glucose paradox of cerebral ischemia: evidence for corticosterone involvement. ( Payne, RS; Schurr, A; Tseng, MT, 2003)
"In vivo models of cerebral ischemia pose a conceptual challenge when compared to in vitro models."5.31Preischemic hyperglycemia-aggravated damage: evidence that lactate utilization is beneficial and glucose-induced corticosterone release is detrimental. ( Miller, JJ; Payne, RS; Schurr, A; Tseng, MT, 2001)
" In rodents, global cerebral ischemia leads to selective CA1 neuronal damage, spatial memory impairments, lasting changes in corticosterone (CORT) secretion, and increased neurogenesis."3.83Dose-related effects of chronic resveratrol administration on neurogenesis, angiogenesis, and corticosterone secretion are associated with improved spatial memory retention following global cerebral ischemia. ( Girbovan, C; Kent, P; Merali, Z; Plamondon, H, 2016)
" Experiment 1 characterized the effects of 10 min forebrain ischemia on corticosterone (CORT) secretion following ischemia and in response to spatial memory assessment in the Barnes maze, as well as the impact of pre-ischemia treatment with the glucocorticoid inhibitor metyrapone (175 mg/kg; s."3.77Changes in HPA reactivity and noradrenergic functions regulate spatial memory impairments at delayed time intervals following cerebral ischemia. ( Milot, MR; Plamondon, H, 2011)
"The purpose of the present study was to determine whether exposure to stress or elevated corticosterone concentrations in the days preceding cerebral ischemia exacerbates ischemic injury as assessed by histological and behavioral outcomes."3.71Social stress exacerbates focal cerebral ischemia in mice. ( DeVries, AC; Hattori, K; Hurn, PD; Morahan, MB; Sugo, N; Traystman, RJ, 2002)
" The present manuscript describes and compares the morphological alterations within the hippocampus in the following experimental models: normal aging, hypoxia, prolonged corticosterone administration, brain ischemia and cholinesterase (ChE) inhibition."3.70Sub-regional hippocampal vulnerability in various animal models leading to cognitive dysfunction. ( Dachir, S; Kadar, T; Levy, A; Shukitt-Hale, B, 1998)
"Rats exposed to forebrain ischemia have reduced injury when anesthetized with isoflurane versus fentanyl + N(2)O."3.70The effects of anesthetics on stress responses to forebrain ischemia and reperfusion in the rat. ( Mackensen, GB; Massey, G; Nellgård, B; Pearlstein, RD; Warner, DS, 2000)
"The protective effect of the alpha 2-receptor antagonist idazoxan against neuronal damage in the neocortex and in the hippocampal CA1 region was studied in rats exposed to 10 min of incomplete forebrain ischemia."3.68Protection against ischemia-induced neuronal damage by the alpha 2-adrenoceptor antagonist idazoxan: influence of time of administration and possible mechanisms of action. ( Gustafson, I; Westerberg, E; Wieloch, T, 1990)
"Under cerebral ischemia or aortic stenosis, changes in plasma and adrenal corticosterone (CS) levels before and after cardiac arrest-preceding type (CPT) and apnea-preceding type (APT) sudden death were examined to determine the response of the hypophyseal adrenocortical system in Wistar rats."3.67[Experimental studies on stress hormones at the time of sudden death (II)--Differences in adrenocortical hormone levels of cardiac arrest-preceding type and apnea preceding type sudden death under cerebral ischemia or aortic stenosis]. ( Douge, K; Ming-Chang, T; Tsunoda, K; Watanabe, T, 1989)
"The glucose paradox of cerebral ischemia (namely, the aggravation of delayed ischemic neuronal damage by preischemic hyperglycemia) has been promoted as proof that lactic acidosis is a detrimental factor in this brain disorder."2.41Bench-to-bedside review: a possible resolution of the glucose paradox of cerebral ischemia. ( Schurr, A, 2002)
"The lactic acidosis hypothesis of cerebral ischemia has relied on a single finding to support its main postulate: pre-ischemic hyperglycemia-aggravated ischemic brain damage."2.41Glucose and the ischemic brain: a sour grape or a sweet treat? ( Schurr, A, 2001)
"They induced stress in rats by cerebral ischemia, collected blood samples at various intervals using both the drop method and the plasma extraction method and then quantified corticosterone by radioimmunoassay."1.38A refined blood collection method for quantifying corticosterone. ( James, JS; Merali, Z; Milot, MR; Plamondon, H, 2012)
"Corticosterone-treated dams also showed an increase in maternal care."1.34Maternal exposure to low levels of corticosterone during lactation protects the adult offspring against ischemic brain damage. ( Alemà, GS; Casolini, P; Catalani, A; Chiodi, V; Cinque, C; Domenici, MR; Galluzzo, M; Maccari, S; Mairesse, J; Marano, G; Matteucci, P; Musumeci, M; Nicoletti, F; Zuena, AR, 2007)
"the glucose paradox of cerebral ischemia, is a well-established phenomenon that has prompted clinicians around the world to closely monitor and control blood glucose levels in surgical cases at high risk for ischemic episodes."1.32The glucose paradox of cerebral ischemia: evidence for corticosterone involvement. ( Payne, RS; Schurr, A; Tseng, MT, 2003)
"In vivo models of cerebral ischemia pose a conceptual challenge when compared to in vitro models."1.31Preischemic hyperglycemia-aggravated damage: evidence that lactate utilization is beneficial and glucose-induced corticosterone release is detrimental. ( Miller, JJ; Payne, RS; Schurr, A; Tseng, MT, 2001)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.63)18.7374
1990's6 (15.79)18.2507
2000's17 (44.74)29.6817
2010's13 (34.21)24.3611
2020's1 (2.63)2.80

Authors

AuthorsStudies
Monjas, L1
Arce, MP1
León, R1
Egea, J1
Pérez, C1
Villarroya, M1
López, MG1
Gil, C1
Conde, S1
Rodríguez-Franco, MI1
Arani Hessari, F1
Sharifi, M1
Yousefifard, M1
Gholamzadeh, R1
Nazarinia, D1
Aboutaleb, N1
Fonken, LK1
Bedrosian, TA1
Zhang, N2
Weil, ZM1
DeVries, AC3
Nelson, RJ1
Jacobsen, KR1
Fauerby, N1
Raida, Z1
Kalliokoski, O1
Hau, J1
Johansen, FF1
Abelson, KS1
de la Tremblaye, PB1
Raymond, J1
Milot, MR3
Merali, Z3
Plamondon, H4
Girbovan, C1
Kent, P1
Fréchou, M1
Zhang, S1
Liere, P1
Delespierre, B1
Soyed, N1
Pianos, A1
Schumacher, M1
Mattern, C1
Guennoun, R1
Kim, LJ1
Coelho, FM1
Araujo, P1
Tedesco, RC1
Souza, RB1
Tufik, S1
Andersen, ML1
Gao, B1
Cam, E1
Jaeger, H1
Zunzunegui, C1
Sarnthein, J1
Bassetti, CL1
Yoo, KY1
Lee, CH1
Choi, JH1
Sohn, Y1
Cho, JH1
Hwang, IK1
Kim, YM1
Won, MH1
Ke, Z1
Yip, SP1
Li, L1
Zheng, XX1
Tong, KY1
Weidenfeld, J1
Leker, RR1
Gai, N1
Teichner, A1
Bener, D1
Ovadia, H1
James, JS1
Schurr, A6
Payne, RS3
Tseng, MT2
Madrigal, JL1
Caso, JR4
de Cristóbal, J1
Cárdenas, A1
Leza, JC4
Lizasoain, I4
Lorenzo, P3
Moro, MA4
Craft, TK1
Glasper, ER1
McCullough, L1
Sugo, N2
Otsuka, T1
Hurn, PD2
Lai, M1
Horsburgh, K1
Bae, SE1
Carter, RN1
Stenvers, DJ1
Fowler, JH1
Yau, JL1
Gomez-Sanchez, CE1
Holmes, MC1
Kenyon, CJ1
Seckl, JR1
Macleod, MR1
Casolini, P1
Domenici, MR1
Cinque, C1
Alemà, GS1
Chiodi, V1
Galluzzo, M1
Musumeci, M1
Mairesse, J1
Zuena, AR1
Matteucci, P1
Marano, G1
Maccari, S1
Nicoletti, F1
Catalani, A1
Pradillo, JM1
Hurtado, O1
Krugers, HJ3
Kemper, RH1
Korf, J3
Ter Horst, GJ1
Knollema, S1
Chou, YC1
Kadar, T1
Dachir, S1
Shukitt-Hale, B1
Levy, A1
Maslam, S2
Van Vuuren, SM1
Joëls, M2
Holsboer, F1
Nellgård, B1
Mackensen, GB1
Massey, G1
Pearlstein, RD1
Warner, DS1
Barr, CS1
Dokas, LA1
Miller, JJ1
Morahan, MB1
Hattori, K1
Traystman, RJ1
Gustafson, I1
Westerberg, E1
Wieloch, T1
Morse, JK1
Davis, JN1
Tsunoda, K1
Douge, K1
Ming-Chang, T1
Watanabe, T1

Reviews

3 reviews available for corticosterone and Brain Ischemia

ArticleYear
Lactate, glucose and energy metabolism in the ischemic brain (Review).
    International journal of molecular medicine, 2002, Volume: 10, Issue:2

    Topics: Acidosis, Lactic; Anaerobiosis; Animals; Brain; Brain Damage, Chronic; Brain Ischemia; Corticosteron

2002
Bench-to-bedside review: a possible resolution of the glucose paradox of cerebral ischemia.
    Critical care (London, England), 2002, Volume: 6, Issue:4

    Topics: Acidosis, Lactic; Animals; Brain Ischemia; Corticosterone; Hormone Antagonists; Humans; Hyperglycemi

2002
Glucose and the ischemic brain: a sour grape or a sweet treat?
    Current opinion in clinical nutrition and metabolic care, 2001, Volume: 4, Issue:4

    Topics: Acidosis, Lactic; Animals; Brain; Brain Ischemia; Corticosterone; Glucose; Humans; Hyperglycemia; Hy

2001

Trials

1 trial available for corticosterone and Brain Ischemia

ArticleYear
Effects of buprenorphine and meloxicam analgesia on induced cerebral ischemia in C57BL/6 male mice.
    Comparative medicine, 2013, Volume: 63, Issue:2

    Topics: Analgesics; Animals; Brain Ischemia; Buprenorphine; Corticosterone; Infarction, Middle Cerebral Arte

2013

Other Studies

34 other studies available for corticosterone and Brain Ischemia

ArticleYear
Enzymatic and solid-phase synthesis of new donepezil-based L- and d-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia.
    European journal of medicinal chemistry, 2017, Apr-21, Volume: 130

    Topics: Alzheimer Disease; Animals; Brain Ischemia; Calcium Channel Blockers; Cholinesterase Inhibitors; Don

2017
Apelin-13 attenuates cerebral ischemia/reperfusion injury through regulating inflammation and targeting the JAK2/STAT3 signaling pathway.
    Journal of chemical neuroanatomy, 2022, Volume: 126

    Topics: Animals; Brain Ischemia; Corticosterone; Hypothalamo-Hypophyseal System; Infarction, Middle Cerebral

2022
Dim light at night impairs recovery from global cerebral ischemia.
    Experimental neurology, 2019, Volume: 317

    Topics: Animals; Brain Ischemia; Cardiopulmonary Resuscitation; Cell Death; Corticosterone; Cytokines; Darkn

2019
Evidence of lasting dysregulation of neuroendocrine and HPA axis function following global cerebral ischemia in male rats and the effect of Antalarmin on plasma corticosterone level.
    Hormones and behavior, 2014, Volume: 65, Issue:3

    Topics: Animals; Behavior, Animal; Brain Ischemia; CA1 Region, Hippocampal; Central Amygdaloid Nucleus; Cort

2014
Dose-related effects of chronic resveratrol administration on neurogenesis, angiogenesis, and corticosterone secretion are associated with improved spatial memory retention following global cerebral ischemia.
    Nutritional neuroscience, 2016, Volume: 19, Issue:8

    Topics: Adrenal Cortex; Animals; Behavior, Animal; Biomarkers; Brain Ischemia; CA1 Region, Hippocampal; Cort

2016
Intranasal delivery of progesterone after transient ischemic stroke decreases mortality and provides neuroprotection.
    Neuropharmacology, 2015, Volume: 97

    Topics: Administration, Intranasal; Animals; Blood-Brain Barrier; Brain; Brain Ischemia; Capillary Permeabil

2015
Sleep restriction reduces the survival time and aggravates the neurological dysfunction and memory impairments in an animal model of cerebral hypoperfusion.
    Brain research, 2016, 08-01, Volume: 1644

    Topics: Animals; Brain Ischemia; CA1 Region, Hippocampal; Cerebral Cortex; Corticosterone; Disease Models, A

2016
Sleep disruption aggravates focal cerebral ischemia in the rat.
    Sleep, 2010, Volume: 33, Issue:7

    Topics: Analysis of Variance; Animals; Body Weight; Brain Ischemia; Corticosterone; Disease Models, Animal;

2010
Changes in corticosteroid hormone receptors in the ischemic gerbil hippocampal CA1 region following repeated restraint stress.
    Neurochemical research, 2011, Volume: 36, Issue:5

    Topics: Animals; Blotting, Western; Brain Ischemia; Corticosterone; Gerbillinae; Hippocampus; Immobilization

2011
The effects of voluntary, involuntary, and forced exercises on brain-derived neurotrophic factor and motor function recovery: a rat brain ischemia model.
    PloS one, 2011, Feb-08, Volume: 6, Issue:2

    Topics: Animals; Brain Ischemia; Brain-Derived Neurotrophic Factor; Corticosterone; Disease Models, Animal;

2011
Changes in HPA reactivity and noradrenergic functions regulate spatial memory impairments at delayed time intervals following cerebral ischemia.
    Hormones and behavior, 2011, Volume: 59, Issue:4

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Analysis of Variance;

2011
The function of the adrenocortical axis in permanent middle cerebral artery occlusion: effect of glucocorticoids on the neurological outcome.
    Brain research, 2011, Aug-17, Volume: 1407

    Topics: Adrenal Cortex; Adrenalectomy; Adrenocorticotropic Hormone; Animals; Anti-Inflammatory Agents; Brain

2011
A refined blood collection method for quantifying corticosterone.
    Lab animal, 2012, Volume: 41, Issue:3

    Topics: Animals; Blood Specimen Collection; Brain Ischemia; Cerebrum; Corticosterone; Male; Metyrapone; Radi

2012
The glucose paradox of cerebral ischemia: evidence for corticosterone involvement.
    Brain research, 2003, May-02, Volume: 971, Issue:1

    Topics: Animals; Blood Glucose; Brain; Brain Ischemia; Corticosterone; Electrophysiology; Hormone Antagonist

2003
Effect of subacute and chronic immobilisation stress on the outcome of permanent focal cerebral ischaemia in rats.
    Brain research, 2003, Jul-25, Volume: 979, Issue:1-2

    Topics: Adenosine Triphosphate; Amino Acid Transport System X-AG; Animals; Behavior, Animal; Blotting, Weste

2003
Social interaction improves experimental stroke outcome.
    Stroke, 2005, Volume: 36, Issue:9

    Topics: Animals; Behavior, Animal; Brain Ischemia; C-Reactive Protein; Cerebral Infarction; Cohort Studies;

2005
The role of tumor necrosis factor-alpha in stress-induced worsening of cerebral ischemia in rats.
    Neuroscience, 2006, Sep-29, Volume: 142, Issue:1

    Topics: ADAM Proteins; ADAM17 Protein; Animals; Antibodies; Behavior, Animal; Blotting, Western; Brain Infar

2006
Involvement of IL-1beta in acute stress-induced worsening of cerebral ischaemia in rats.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2007, Volume: 17, Issue:9

    Topics: Animals; Antibodies; Behavior, Animal; Brain Infarction; Brain Ischemia; Corticosterone; Disease Mod

2007
Forebrain mineralocorticoid receptor overexpression enhances memory, reduces anxiety and attenuates neuronal loss in cerebral ischaemia.
    The European journal of neuroscience, 2007, Volume: 25, Issue:6

    Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Brain Ischemia; Cell Death; Corticosterone

2007
Maternal exposure to low levels of corticosterone during lactation protects the adult offspring against ischemic brain damage.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Jun-27, Volume: 27, Issue:26

    Topics: Aging; Animals; Animals, Newborn; Brain Ischemia; Corticosterone; Female; Hypothalamo-Hypophyseal Sy

2007
Toll-like receptor 4 is involved in subacute stress-induced neuroinflammation and in the worsening of experimental stroke.
    Stroke, 2008, Volume: 39, Issue:4

    Topics: Animals; Behavior, Animal; Brain Ischemia; Corticosterone; Cyclooxygenase 2; Encephalitis; Gene Expr

2008
Metyrapone reduces rat brain damage and seizures after hypoxia-ischemia: an effect independent of modulation of plasma corticosterone levels?
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1998, Volume: 18, Issue:4

    Topics: Animals; Blood Glucose; Body Temperature; Brain Damage, Chronic; Brain Ischemia; Corticosterone; Epi

1998
Corticosterone exacerbates cyanide-induced cell death in hippocampal cultures: role of astrocytes.
    Neurochemistry international, 1998, Volume: 32, Issue:3

    Topics: Animals; Aspartic Acid; Astrocytes; Brain Ischemia; Cell Death; Cells, Cultured; Corticosterone; Cya

1998
Sub-regional hippocampal vulnerability in various animal models leading to cognitive dysfunction.
    Journal of neural transmission (Vienna, Austria : 1996), 1998, Volume: 105, Issue:8-9

    Topics: Aging; Animals; Atmospheric Pressure; Brain Ischemia; Cholinesterase Inhibitors; Cognition Disorders

1998
Postischemic steroid modulation: effects on hippocampal neuronal integrity and synaptic plasticity.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1999, Volume: 19, Issue:10

    Topics: Action Potentials; Animals; Brain Ischemia; Corticosterone; Dexamethasone; Electrophysiology; Epilep

1999
The corticosterone synthesis inhibitor metyrapone prevents hypoxia/ischemia-induced loss of synaptic function in the rat hippocampus.
    Stroke, 2000, Volume: 31, Issue:5

    Topics: Animals; Brain Ischemia; Corticosterone; Hippocampus; Hypoxia; Male; Metyrapone; Rats; Rats, Wistar;

2000
The effects of anesthetics on stress responses to forebrain ischemia and reperfusion in the rat.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:1

    Topics: Anesthetics; Animals; Brain Ischemia; Corticosterone; Fentanyl; Interleukin-6; Isoflurane; Metyrapon

2000
Corticosterone-aggravated ischemic neuronal damage in vitro is relieved by vanadate.
    Neuroreport, 2001, May-08, Volume: 12, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Brain Ischemia; Cell Hypoxia; Corticosterone; Dose-Response Relat

2001
Regulation of pp60(c-src) synthesis in rat hippocampal slices by in vitro ischemia and glucocorticoid administration.
    Journal of neuroscience research, 2001, Aug-15, Volume: 65, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Brain Ischemia; Corticosterone; Hippocampus; M

2001
Preischemic hyperglycemia-aggravated damage: evidence that lactate utilization is beneficial and glucose-induced corticosterone release is detrimental.
    Journal of neuroscience research, 2001, Dec-01, Volume: 66, Issue:5

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Animals; Blood Glucose; Brain Ischemia; Corticostero

2001
Social stress exacerbates focal cerebral ischemia in mice.
    Stroke, 2002, Volume: 33, Issue:6

    Topics: Animals; Behavior, Animal; Brain Ischemia; Cognition; Corticosterone; Disease Models, Animal; Diseas

2002
Protection against ischemia-induced neuronal damage by the alpha 2-adrenoceptor antagonist idazoxan: influence of time of administration and possible mechanisms of action.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1990, Volume: 10, Issue:6

    Topics: Adrenergic alpha-Antagonists; Animals; Brain Ischemia; Corticosterone; Dioxanes; Idazoxan; Male; Neu

1990
Regulation of ischemic hippocampal damage in the gerbil: adrenalectomy alters the rate of CA1 cell disappearance.
    Experimental neurology, 1990, Volume: 110, Issue:1

    Topics: Adrenalectomy; Animals; Brain Ischemia; Cell Survival; Corticosterone; Gerbillinae; Glucocorticoids;

1990
[Experimental studies on stress hormones at the time of sudden death (II)--Differences in adrenocortical hormone levels of cardiac arrest-preceding type and apnea preceding type sudden death under cerebral ischemia or aortic stenosis].
    Nihon hoigaku zasshi = The Japanese journal of legal medicine, 1989, Volume: 43, Issue:6

    Topics: Adrenal Glands; Animals; Aortic Valve Stenosis; Apnea; Brain Ischemia; Corticosterone; Death, Sudden

1989