Page last updated: 2024-11-06

corticosterone and Atherogenesis

corticosterone has been researched along with Atherogenesis in 19 studies

Research Excerpts

ExcerptRelevanceReference
"Corticosterone treatment significantly increased atherosclerotic plaque area at the aortic root."5.40Corticosterone accelerates atherosclerosis in the apolipoprotein E-deficient mouse. ( Higashida, K; Higuchi, M; Lira, VA; Okutsu, M; Peake, J; Suzuki, K, 2014)
" Still, hopes that CETP inhibition could reduce atherosclerosis were dented when the clinical development of one such inhibitor, torcetrapib, was halted because of an unexpected finding of increased cardiovascular and noncardiovascular mortality against a background of elevated blood pressure and plasma aldosterone levels."4.85The pharmacology and off-target effects of some cholesterol ester transfer protein inhibitors. ( Stroes, ES; Vergeer, M, 2009)
"Corticosterone treatment increased body weight and food intake for the duration of the treatment and increased gonadal and subcutaneous white adipose tissue weight in transient group by +35% and +31%, and in the continuous group by +140% and 110%."3.79Both transient and continuous corticosterone excess inhibit atherosclerotic plaque formation in APOE*3-leiden.CETP mice. ( Auvinen, HE; Biermasz, NR; Havekes, LM; Meijer, OC; Pereira, AM; Princen, H; Rensen, PC; Romijn, JA; Smit, JW; Wang, Y, 2013)
"Although atherosclerosis was reduced in CD40AKO mice, plaques contained more activated T cells and larger necrotic cores."1.91Adipocytes control hematopoiesis and inflammation through CD40 signaling. ( Aarts, SABM; Atzler, D; Beckers, L; Bosmans, LA; Den Toom, M; Gijbels, MJJ; Kooijman, S; Lutgens, E; Poels, K; Reiche, ME; Rensen, PCN; Van Tiel, CM; Vos, WG; Weber, C, 2023)
"Corticosterone treatment significantly increased atherosclerotic plaque area at the aortic root."1.40Corticosterone accelerates atherosclerosis in the apolipoprotein E-deficient mouse. ( Higashida, K; Higuchi, M; Lira, VA; Okutsu, M; Peake, J; Suzuki, K, 2014)
"Atherosclerosis was quantified in cross-sections of innominate artery and en face in thoracic aorta."1.35Effects of social isolation and environmental enrichment on atherosclerosis in ApoE-/- mice. ( Andersson, IJ; Bergström, G; Bernberg, E; Gan, LM; Johansson, ME; Naylor, AS, 2008)
"Atherosclerosis is often related to vascular endothelial dysfunction."1.35Maternal stress and development of atherosclerosis in the adult apolipoprotein E-deficient mouse offspring. ( Andersson, IJ; Davidge, ST; Jiang, YY, 2009)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (36.84)29.6817
2010's11 (57.89)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Reiche, ME2
Poels, K2
Bosmans, LA2
Vos, WG2
Van Tiel, CM2
Gijbels, MJJ2
Aarts, SABM2
Den Toom, M2
Beckers, L2
Weber, C2
Atzler, D2
Rensen, PCN2
Kooijman, S2
Lutgens, E2
van der Geest, R1
van der Sluis, RJ3
Groen, AK1
Van Eck, M1
Hoekstra, M3
Auvinen, HE1
Wang, Y1
Princen, H1
Romijn, JA1
Havekes, LM1
Smit, JW1
Meijer, OC1
Biermasz, NR1
Rensen, PC1
Pereira, AM1
Frodermann, V1
van den Aardweg, T1
Kuiper, J1
Okutsu, M1
Lira, VA1
Higashida, K1
Peake, J1
Higuchi, M1
Suzuki, K1
Tang, YL1
Jiang, JH1
Wang, S1
Liu, Z1
Tang, XQ1
Peng, J1
Yang, YZ1
Gu, HF1
Bittencourt, CR1
Izar, MC1
Schwerz, VL1
Póvoa, RM1
Fonseca, HA1
Fonseca, MI1
Bianco, HT1
França, CN1
Ferreira, CE1
Fonseca, FA1
Bernberg, E3
Andersson, IJ4
Gan, LM1
Naylor, AS1
Johansson, ME3
Bergström, G2
Tidstrand, S1
Neves, VJ1
Moura, MJ1
Tamascia, ML1
Ferreira, R1
Silva, NS1
Costa, R1
Montemor, PL1
Narvaes, EA1
Bernardes, CF1
Novaes, PD1
Marcondes, FK1
Jiang, YY1
Davidge, ST2
Vergeer, M1
Stroes, ES1
Sankaralingam, S1
van Puijvelde, GH1
Van Berkel, TJ1
Ulleryd, MA1
Bergström, GM1
Pereira, CD1
Azevedo, I1
Monteiro, R1
Martins, MJ1
Najafi, AH1
Aghili, N1
Tilan, JU1
Andrews, JA1
Peng, X1
Lassance-Soares, RM1
Sood, S1
Alderman, LO1
Abe, K1
Li, L1
Kolodgie, FD1
Virmani, R1
Zukowska, Z1
Epstein, SE1
Burnett, MS1
McCann, SM1
Mastronardi, C1
de Laurentiis, A1
Rettori, V1
Nuotio-Antar, AM1
Hachey, DL1
Hasty, AH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Prednisone on Atherogenesis as Studied in the Macrophage Foam Cell Formation Model System.[NCT03367663]Early Phase 110 participants (Actual)Interventional2018-01-17Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for corticosterone and Atherogenesis

ArticleYear
The pharmacology and off-target effects of some cholesterol ester transfer protein inhibitors.
    The American journal of cardiology, 2009, Nov-16, Volume: 104, Issue:10 Suppl

    Topics: Aldosterone; Amides; Animals; Anticholesteremic Agents; Atherosclerosis; Blood Pressure; Cholesterol

2009
11β-Hydroxysteroid dehydrogenase type 1: relevance of its modulation in the pathophysiology of obesity, the metabolic syndrome and type 2 diabetes mellitus.
    Diabetes, obesity & metabolism, 2012, Volume: 14, Issue:10

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipose Tissue; Animals; Anti-Inflammatory Agents; Athe

2012
The nitric oxide theory of aging revisited.
    Annals of the New York Academy of Sciences, 2005, Volume: 1057

    Topics: Aging; Animals; Atherosclerosis; Central Nervous System; Corticosterone; Gonadotropin-Releasing Horm

2005

Other Studies

16 other studies available for corticosterone and Atherogenesis

ArticleYear
Adipocytes control hematopoiesis and inflammation through CD40 signaling.
    Haematologica, 2023, Jul-01, Volume: 108, Issue:7

    Topics: Adipocytes; Animals; Atherosclerosis; Cardiovascular Diseases; CD40 Antigens; CD40 Ligand; Corticost

2023
Adipocytes control hematopoiesis and inflammation through CD40 signaling.
    Haematologica, 2023, Jul-01, Volume: 108, Issue:7

    Topics: Adipocytes; Animals; Atherosclerosis; Cardiovascular Diseases; CD40 Antigens; CD40 Ligand; Corticost

2023
Adipocytes control hematopoiesis and inflammation through CD40 signaling.
    Haematologica, 2023, Jul-01, Volume: 108, Issue:7

    Topics: Adipocytes; Animals; Atherosclerosis; Cardiovascular Diseases; CD40 Antigens; CD40 Ligand; Corticost

2023
Adipocytes control hematopoiesis and inflammation through CD40 signaling.
    Haematologica, 2023, Jul-01, Volume: 108, Issue:7

    Topics: Adipocytes; Animals; Atherosclerosis; Cardiovascular Diseases; CD40 Antigens; CD40 Ligand; Corticost

2023
Cholestasis-associated glucocorticoid overexposure does not increase atherogenesis.
    The Journal of endocrinology, 2019, Volume: 242, Issue:2

    Topics: 1-Naphthylisothiocyanate; Animals; Apolipoproteins E; Atherosclerosis; Cholestasis; Cholesterol; Cor

2019
Both transient and continuous corticosterone excess inhibit atherosclerotic plaque formation in APOE*3-leiden.CETP mice.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Adipose Tissue; Animal Feed; Animals; Apolipoprotein E3; Atherosclerosis; Body Composition; Body Wei

2013
Leukocytosis and enhanced susceptibility to endotoxemia but not atherosclerosis in adrenalectomized APOE knockout mice.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Adrenalectomy; Animals; Apolipoproteins E; Atherosclerosis; Corticosterone; Disease Models, Animal;

2013
Corticosterone accelerates atherosclerosis in the apolipoprotein E-deficient mouse.
    Atherosclerosis, 2014, Volume: 232, Issue:2

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Chemokine CCL2; Corticosterone; Cytokines; Dyslipidemia

2014
TLR4/NF-κB signaling contributes to chronic unpredictable mild stress-induced atherosclerosis in ApoE-/- mice.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Corticosterone; Cytokines; Disease Models, Anima

2015
Effects of High-Intensity Training of Professional Runners on Myocardial Hypertrophy and Subclinical Atherosclerosis.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Adult; Atherosclerosis; Athletes; Cardiomegaly; Carotid Intima-Media Thickness; Case-Control Studies

2016
Effects of social isolation and environmental enrichment on atherosclerosis in ApoE-/- mice.
    Stress (Amsterdam, Netherlands), 2008, Volume: 11, Issue:5

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Blood Pressure; Corticosterone; Drinking Behavior; Envi

2008
Repeated exposure to stressors do not accelerate atherosclerosis in ApoE-/- mice.
    Atherosclerosis, 2009, Volume: 204, Issue:1

    Topics: Animals; Aorta, Thoracic; Apolipoproteins E; Atherosclerosis; Blood Pressure; Body Weight; Chronic D

2009
Proatherosclerotic effects of chronic stress in male rats: altered phenylephrine sensitivity and nitric oxide synthase activity of aorta and circulating lipids.
    Stress (Amsterdam, Netherlands), 2009, Volume: 12, Issue:4

    Topics: Animals; Aorta, Thoracic; Atherosclerosis; Corticosterone; Lipids; Male; Nitric Oxide Synthase; Phen

2009
Maternal stress and development of atherosclerosis in the adult apolipoprotein E-deficient mouse offspring.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 296, Issue:3

    Topics: Animals; Aorta, Thoracic; Apolipoproteins E; Atherosclerosis; Birth Weight; Cholesterol; Corticoster

2009
Restraint stress up-regulates lectin-like oxidized low-density lipoprotein receptor-1 in aorta of apolipoprotein E-deficient mice.
    Stress (Amsterdam, Netherlands), 2010, Volume: 13, Issue:5

    Topics: Animals; Antioxidants; Aorta, Thoracic; Apolipoproteins E; Atherosclerosis; Body Weight; Corticoster

2010
Adrenalectomy stimulates the formation of initial atherosclerotic lesions: reversal by adrenal transplantation.
    Atherosclerosis, 2012, Volume: 221, Issue:1

    Topics: Adrenal Glands; Adrenalectomy; Animals; Aortic Diseases; Atherosclerosis; Cholesterol; Corticosteron

2012
Social disruption stress increases IL-6 levels and accelerates atherosclerosis in ApoE-/- mice.
    Atherosclerosis, 2012, Volume: 221, Issue:2

    Topics: Animals; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Chemokine CXCL1; Corticosterone; Disea

2012
A new murine model of stress-induced complex atherosclerotic lesions.
    Disease models & mechanisms, 2013, Volume: 6, Issue:2

    Topics: Animals; Atherosclerosis; Blood Pressure; Cholesterol; Coronary Stenosis; Corticosterone; Disease Mo

2013
Carbenoxolone treatment attenuates symptoms of metabolic syndrome and atherogenesis in obese, hyperlipidemic mice.
    American journal of physiology. Endocrinology and metabolism, 2007, Volume: 293, Issue:6

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipose Tissue; Agouti Signaling Protein; Animals; Athe

2007