Page last updated: 2024-11-06

corticosterone and Anhedonia

corticosterone has been researched along with Anhedonia in 56 studies

Anhedonia: Inability to experience pleasure due to impairment or dysfunction of normal psychological and neurobiological mechanisms. It is a symptom of many PSYCHOTIC DISORDERS (e.g., DEPRESSIVE DISORDER, MAJOR; and SCHIZOPHRENIA).

Research Excerpts

ExcerptRelevanceReference
" Here we aimed to compare the effects of (R)-norketamine ((R)-NK), (S)-NK, (2R,6R)-HNK, and (2S,6S)-HNK in a mouse model of depression induced by chronic corticosterone (CORT) injection."7.96(S)-norketamine and (2S,6S)-hydroxynorketamine exert potent antidepressant-like effects in a chronic corticosterone-induced mouse model of depression. ( Ago, Y; Chen, L; Hashimoto, H; Hashimoto, K; Higuchi, M; Kasai, A; Naito, M; Nakagawa, S; Nakazawa, T; Seiriki, K; Tanabe, W; Tsukada, S; Yamaguchi, T; Yokoyama, R, 2020)
"Pregnancy is a very complex and highly stressful time in which women become more physically and emotionally vulnerable."5.72Swimming exercise strain-dependently affects maternal care and depression-related behaviors through gestational corticosterone and brain serotonin in postpartum dams. ( Ebrahimian, F; Masrour, FF; Najdi, N; Salari, AA, 2022)
"Corticosterone plasma level was increased in the CUMS compared to the non-stressed group (p < 0."5.56Valproic acid administration exerts protective effects against stress-related anhedonia in rats. ( Barati, M; Eslami, M; Goudarzi, M; Mehrabi, S; Nahavandi, A; Shahbazi, A, 2020)
"Corticosterone treatment altered all parameters in behavioral tests, leading to a depressive- and anxious-like behavior."5.51Reversal effect of Riparin IV in depression and anxiety caused by corticosterone chronic administration in mice. ( Barbosa Filho, JM; Capibaribe, VCC; Chaves, RC; da Silva, DMA; de Carvalho, AMR; de Sousa, FCF; Gutierrez, SJC; Lopes, IS; Macêdo, DS; Mallmann, ASV; Oliveira, ICM; Oliveira, NF; Valentim, JT; Vasconcelos, SMM, 2019)
"Memantine treatment reversed anhedonia and the increase of adrenal gland weight, normalized corticosterone levels and increased BDNF protein levels in the prefrontal cortex in stressed rats."5.38Memantine treatment reverses anhedonia, normalizes corticosterone levels and increases BDNF levels in the prefrontal cortex induced by chronic mild stress in rats. ( Abelaira, HM; Fries, GR; Kapczinski, F; Quevedo, J; Réus, GZ; Stringari, RB, 2012)
" Here we aimed to compare the effects of (R)-norketamine ((R)-NK), (S)-NK, (2R,6R)-HNK, and (2S,6S)-HNK in a mouse model of depression induced by chronic corticosterone (CORT) injection."3.96(S)-norketamine and (2S,6S)-hydroxynorketamine exert potent antidepressant-like effects in a chronic corticosterone-induced mouse model of depression. ( Ago, Y; Chen, L; Hashimoto, H; Hashimoto, K; Higuchi, M; Kasai, A; Naito, M; Nakagawa, S; Nakazawa, T; Seiriki, K; Tanabe, W; Tsukada, S; Yamaguchi, T; Yokoyama, R, 2020)
"Agmatine, an endogenous neuromodulator, is a potential candidate to constitute an adjuvant/monotherapy for the management of depression."3.83Agmatine, by Improving Neuroplasticity Markers and Inducing Nrf2, Prevents Corticosterone-Induced Depressive-Like Behavior in Mice. ( Buendia, I; Casas, AI; Cuadrado, A; Egea, J; Freitas, AE; Gómez-Rangel, V; Lopez, MG; Navarro, E; Ortiz, JA; Parada, E; Rodrigues, ALS; Ruiz-Nuño, A; Wojnicz, A, 2016)
" In the current study the association between diurnal pattern of key phase markers (melatonin, corticosterone, and core body temperature) and anhedonic-like behavior was investigated using the highly validated rat chronic mild stress (CMS) model of depression."3.83Disturbed diurnal rhythm of three classical phase markers in the chronic mild stress rat model of depression. ( Bouzinova, EV; Christiansen, SL; Højgaard, K; Wiborg, O, 2016)
" We used several well-validated animal models of depression to assess the antidepressant-like activity of LPM580153, followed by a neurotransmitter uptake assay and a corticosterone-induced cell injury model to explore its mechanism of action."3.83Antidepressant-like Effects of LPM580153, A Novel Potent Triple Reuptake Inhibitor. ( Liu, Q; Meng, X; Shao, J; Tian, J; Wang, H; Ye, L; Zhang, F; Zhong, Y, 2016)
" The trial's goal was to investigate the activity of Rip III in mice exposed to corticosterone-induced chronic depression model."3.81Subchronic administration of riparin III induces antidepressive-like effects and increases BDNF levels in the mouse hippocampus. ( Barbosa-Filho, JM; de França Fonteles, MM; de Sousa, FC; Gaspar, DM; Gutierrez, SJ; Oliveira, IC; Rodrigues, GC; Vasconcelos, AS; Vasconcelos, SM; Vidal, LT, 2015)
" Anhedonia, brain BDNF and circulating corticosterone levels, considered endophenotypes of depression, were investigated."3.79Antidepressant treatment outcome depends on the quality of the living environment: a pre-clinical investigation in mice. ( Alleva, E; Branchi, I; Capoccia, S; Cirulli, F; D'Andrea, I; Poggini, S; Santarelli, S, 2013)
" Aim of this paper was to study the relationship between neuroendocrine activation (circulating corticosterone and brain BDNF levels) and a wide array of depression- and anxiety-like behaviours (anhedonia, behavioural despair, generalised and social anxiety) resulting from exposure to chronic stress."3.78Social deprivation stress is a triggering factor for the emergence of anxiety- and depression-like behaviours and leads to reduced brain BDNF levels in C57BL/6J mice. ( Alleva, E; Bellisario, V; Berry, A; Calza, A; Capoccia, S; Cirulli, F; Tirassa, P, 2012)
"On the basis of CMS-induced changes of sucrose intake, a reliable measure for anhedonia, rats were divided into "resilient" and "anhedonic" groups."3.78Chronic mild stress-induced depression-like symptoms in rats and abnormalities in catecholamine uptake in small arteries. ( Aalkjaer, C; Boedtkjer, DB; Bouzinova, EV; Broegger, T; Matchkov, VV; Møller-Nielsen, N; Wiborg, O, 2012)
" Here, we investigated whether prenatal stress--in the form of gestational exposure to corticosterone supplemented in the maternal drinking water (100 mg/l) during the last week of pregnancy--combined with a pharmacological stimulation of the ECS during adolescence (daily fatty acid amide hydrolase URB597 i."3.78Prenatal stress and peripubertal stimulation of the endocannabinoid system differentially regulate emotional responses and brain metabolism in mice. ( Canese, R; Ceci, C; Laviola, G; Macrì, S, 2012)
"Pregnancy is a very complex and highly stressful time in which women become more physically and emotionally vulnerable."1.72Swimming exercise strain-dependently affects maternal care and depression-related behaviors through gestational corticosterone and brain serotonin in postpartum dams. ( Ebrahimian, F; Masrour, FF; Najdi, N; Salari, AA, 2022)
"Depression is a psychiatric disorder leading to anhedonia and lack of interest and motivation."1.72Antidepressive-Like Effect of ( Alhalmi, A; Kumar, G; Pathak, D; Sharma, A; Singh, T; Virmani, T, 2022)
"Corticosterone (CORT) treatment significantly enhanced Bag-1/GR complex formation and GR mitochondrial translocation in cultured rat cortical neurons after treatment for 30 min and 24 hr."1.62Bag-1 mediates glucocorticoid receptor trafficking to mitochondria after corticosterone stimulation: Potential role in regulating affective resilience. ( Bao, H; Du, J; Feng, L; Hou, Y; Hunter, RG; Jia, Y; K Manji, H; Li, H; Luo, S; S McEwen, B; Wang, G; Xiao, C; Yuan, P; Zhang, Y, 2021)
"Major depressive disorder is a common debilitating mental health problem that represents one of the leading causes of disability."1.62Adult neurogenesis augmentation attenuates anhedonia and HPA axis dysregulation in a mouse model of chronic stress and depression. ( Belzung, C; Brizard, B; Eliwa, H; Hen, R; Le Guisquet, AM; Surget, A, 2021)
"Corticosterone plasma level was increased in the CUMS compared to the non-stressed group (p < 0."1.56Valproic acid administration exerts protective effects against stress-related anhedonia in rats. ( Barati, M; Eslami, M; Goudarzi, M; Mehrabi, S; Nahavandi, A; Shahbazi, A, 2020)
"Corticosterone effect was associated with depletion of reduced glutathione and increase of lipid peroxidation, in addition to modification of biogenic amines; decreased serotonin and dopamine."1.56Oleuropein Reverses Repeated Corticosterone-Induced Depressive-Like Behavior in mice: Evidence of Modulating Effect on Biogenic Amines. ( Al-Rasheed, N; Attia, HA; Badr, AM, 2020)
"Corticosterone treatment altered all parameters in behavioral tests, leading to a depressive- and anxious-like behavior."1.51Reversal effect of Riparin IV in depression and anxiety caused by corticosterone chronic administration in mice. ( Barbosa Filho, JM; Capibaribe, VCC; Chaves, RC; da Silva, DMA; de Carvalho, AMR; de Sousa, FCF; Gutierrez, SJC; Lopes, IS; Macêdo, DS; Mallmann, ASV; Oliveira, ICM; Oliveira, NF; Valentim, JT; Vasconcelos, SMM, 2019)
"Agmatine is an endogenous neuromodulator that has been shown to have beneficial effects in the central nervous system, including antidepressant-like effects in animals."1.48Antidepressant and pro-neurogenic effects of agmatine in a mouse model of stress induced by chronic exposure to corticosterone. ( Azevedo, DP; Brocardo, PS; Fraga, DB; Gil-Mohapel, J; Melleu, FF; Neis, VB; Olescowicz, G; Rodrigues, ALS; Rosa, PB, 2018)
"Anhedonia was evaluated using the sucrose preference test (SPT), and behavioural despair was evaluated using the forced swim test (FST) and tail suspension test (TST)."1.42Depressive-like behaviours and decreased dendritic branching in the medial prefrontal cortex of mice with tumors: A novel validated model of cancer-induced depression. ( Frey, BN; Nashed, MG; Seidlitz, EP; Singh, G, 2015)
" In addition, our results showed that neither imipramine nor Sanyuansan at any dosage increased spontaneous motor activity."1.42Antidepressant-like effects of Sanyuansan in the mouse forced swim test, tail suspension test, and chronic mild stress model. ( Gou, XJ; He, G; Lin, B; Peng, C; Yan, S; You, ZL; Zhao, QY, 2015)
"Post-traumatic stress disorder (PTSD) is a condition which can develop from exposure to a severe traumatic event such as those occurring during wars or natural disasters."1.40Moderate treadmill exercise rescues anxiety and depression-like behavior as well as memory impairment in a rat model of posttraumatic stress disorder. ( Alkadhi, K; Allam, F; Dao, AT; Li, L; Patki, G; Salim, S; Solanki, N, 2014)
"Neuropathic pain was induced by chronic constriction injury of the sciatic nerve in wild-type and TNFR1(-/-) mice."1.40Neuropathic pain-induced depressive-like behavior and hippocampal neurogenesis and plasticity are dependent on TNFR1 signaling. ( Bernardes, D; Bethea, JR; Brambilla, R; Dellarole, A; Grilli, M; Morton, P; Summers, S; Walters, W, 2014)
"Melancholic depression has typically been associated with HPA hyperactivity, while atypical depression has been linked with HPA hypoactivity."1.38Lack of elevations in glucocorticoids correlates with dysphoria-like behavior after repeated social defeat. ( Bhatnagar, S; Bowens, N; Heydendael, W; Jacobson, L, 2012)
"Pneumococcal meningitis is a severe infectious disease of the central nervous system, associated with acute inflammation and might cause damage to the host, such as deafness, blindness, seizure, and learning deficits."1.38Imipramine reverses depressive-like parameters in pneumococcal meningitis survivor rats. ( Barichello, T; Cipriano, AL; Comim, CM; Costa, CS; Generoso, JS; Milioli, G; Moreira, AP; Quevedo, J; Teixeira, AL; Vilela, MC, 2012)
"Memantine treatment reversed anhedonia and the increase of adrenal gland weight, normalized corticosterone levels and increased BDNF protein levels in the prefrontal cortex in stressed rats."1.38Memantine treatment reverses anhedonia, normalizes corticosterone levels and increases BDNF levels in the prefrontal cortex induced by chronic mild stress in rats. ( Abelaira, HM; Fries, GR; Kapczinski, F; Quevedo, J; Réus, GZ; Stringari, RB, 2012)
"Depression is a debilitating mental illness and is often comorbid with metabolic disorders such as type 2 diabetes."1.38Adiponectin is critical in determining susceptibility to depressive behaviors and has antidepressant-like activity. ( Cheng, SY; Ding, J; Guo, M; Liu, F; Liu, J; Liu, M; Lu, XY; Scherer, PE; Zhang, D, 2012)

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's45 (80.36)24.3611
2020's11 (19.64)2.80

Authors

AuthorsStudies
Moraga-Amaro, R1
Guerrin, CGJ1
Reali Nazario, L1
Lima Giacobbo, B1
J O Dierckx, RA1
Stehberg, J1
de Vries, EFJ1
Doorduin, J1
Ebrahimian, F1
Najdi, N1
Masrour, FF1
Salari, AA1
Sharma, A1
Singh, T1
Pathak, D1
Virmani, T1
Kumar, G1
Alhalmi, A1
Orrico-Sanchez, A1
Guiard, BP1
Manta, S1
Callebert, J1
Launay, JM1
Louis, F1
Paccard, A1
Gruszczynski, C1
Betancur, C1
Vialou, V1
Gautron, S1
Goñi-Balentziaga, O1
Garmendia, L1
Labaka, A1
Lebeña, A1
Beitia, G1
Gómez-Lázaro, E1
Vegas, O1
Goudarzi, M1
Nahavandi, A1
Mehrabi, S1
Eslami, M1
Shahbazi, A1
Barati, M1
Yokoyama, R1
Higuchi, M1
Tanabe, W1
Tsukada, S1
Naito, M1
Yamaguchi, T1
Chen, L1
Kasai, A1
Seiriki, K1
Nakazawa, T1
Nakagawa, S1
Hashimoto, K1
Hashimoto, H1
Ago, Y1
Badr, AM1
Attia, HA1
Al-Rasheed, N1
Luo, S1
Hou, Y1
Zhang, Y1
Feng, L1
Hunter, RG1
Yuan, P1
Jia, Y1
Li, H1
Wang, G1
K Manji, H1
S McEwen, B1
Xiao, C1
Bao, H1
Du, J1
Nakatake, Y1
Furuie, H1
Ukezono, M1
Yamada, M2
Yoshizawa, K1
Eliwa, H1
Brizard, B1
Le Guisquet, AM1
Hen, R1
Belzung, C1
Surget, A1
Mohammadi, SA1
Burton, TJ1
Christie, MJ1
Markov, DD1
Yatsenko, KA1
Inozemtseva, LS1
Grivennikov, IA1
Myasoedov, NF1
Dolotov, OV1
Winkler, Z1
Kuti, D1
Ferenczi, S1
Gulyás, K1
Polyák, Á1
Kovács, KJ1
Olescowicz, G1
Neis, VB1
Fraga, DB1
Rosa, PB1
Azevedo, DP1
Melleu, FF1
Brocardo, PS1
Gil-Mohapel, J1
Rodrigues, ALS2
Agusti, A1
Moya-Pérez, A1
Campillo, I1
Montserrat-de la Paz, S1
Cerrudo, V1
Perez-Villalba, A1
Sanz, Y1
Zhang, YP1
Wang, HY1
Zhang, C1
Liu, BP1
Peng, ZL1
Li, YY1
Liu, FM1
Song, C1
Houwing, DJ1
Ramsteijn, AS1
Riemersma, IW1
Olivier, JDA1
Stevenson, JR1
McMahon, EK1
Boner, W1
Haussmann, MF1
Chaves, RC1
Mallmann, ASV1
Oliveira, NF1
Oliveira, ICM1
Capibaribe, VCC1
da Silva, DMA1
Lopes, IS1
Valentim, JT1
de Carvalho, AMR1
Macêdo, DS1
Vasconcelos, SMM1
Gutierrez, SJC1
Barbosa Filho, JM1
de Sousa, FCF1
Highland, JN1
Zanos, P1
Georgiou, P1
Gould, TD1
Di Segni, M1
Andolina, D1
D'Addario, SL1
Babicola, L1
Ielpo, D1
Luchetti, A1
Pascucci, T1
Lo Iacono, L1
D'Amato, FR1
Ventura, R1
Branchi, I2
Santarelli, S2
Capoccia, S2
Poggini, S1
D'Andrea, I2
Cirulli, F2
Alleva, E3
Xing, Y1
He, J1
Hou, J1
Lin, F1
Tian, J2
Kurihara, H1
Kim, KS2
Kang, YM1
Kang, Y1
Park, TS1
Park, HY1
Kim, YJ1
Han, BS1
Kim, CH1
Lee, CH1
Ardayfio, PA1
Han, PL1
Jung, BH1
Rinwa, P1
Kumar, A1
Patki, G1
Li, L1
Allam, F1
Solanki, N1
Dao, AT1
Alkadhi, K1
Salim, S1
Hill, RA1
Klug, M1
Kiss Von Soly, S1
Binder, MD1
Hannan, AJ1
van den Buuse, M1
Dellarole, A1
Morton, P1
Brambilla, R1
Walters, W1
Summers, S1
Bernardes, D1
Grilli, M1
Bethea, JR1
Jacobson, L2
O'Leary, OF1
Felice, D1
Galimberti, S1
Savignac, HM1
Bravo, JA1
Crowley, T1
El Yacoubi, M1
Vaugeois, JM1
Gassmann, M1
Bettler, B1
Dinan, TG1
Cryan, JF1
Sayd, A1
Antón, M1
Alén, F1
Caso, JR1
Pavón, J1
Leza, JC1
Rodríguez de Fonseca, F1
García-Bueno, B1
Orio, L1
Vasconcelos, AS1
Oliveira, IC1
Vidal, LT1
Rodrigues, GC1
Gutierrez, SJ1
Barbosa-Filho, JM1
Vasconcelos, SM1
de França Fonteles, MM1
Gaspar, DM1
de Sousa, FC1
Freitas, AE1
Egea, J1
Buendia, I1
Gómez-Rangel, V1
Parada, E1
Navarro, E1
Casas, AI1
Wojnicz, A1
Ortiz, JA1
Cuadrado, A1
Ruiz-Nuño, A1
Lopez, MG1
Yi, LT1
Luo, L1
Wu, YJ1
Liu, BB1
Liu, XL1
Geng, D1
Liu, Q2
Nashed, MG1
Seidlitz, EP1
Frey, BN1
Singh, G1
Carnevali, L1
Vacondio, F1
Rossi, S1
Callegari, S1
Macchi, E1
Spadoni, G1
Bedini, A1
Rivara, S1
Mor, M1
Sgoifo, A1
Zurawek, D1
Kusmider, M1
Faron-Gorecka, A1
Gruca, P1
Pabian, P1
Kolasa, M1
Solich, J1
Szafran-Pilch, K1
Papp, M1
Dziedzicka-Wasylewska, M1
Xu, LZ1
Liu, LJ1
Yuan, M1
Li, SX1
Yue, XD1
Lai, JL1
Lu, L1
Dutheil, S1
Ota, KT1
Wohleb, ES1
Rasmussen, K1
Duman, RS1
Yan, S1
You, ZL1
Zhao, QY1
Peng, C1
He, G1
Gou, XJ1
Lin, B1
Vega-Rivera, NM1
Ortiz-López, L1
Gómez-Sánchez, A1
Oikawa-Sala, J1
Estrada-Camarena, EM1
Ramírez-Rodríguez, GB1
Christiansen, SL1
Højgaard, K1
Wiborg, O2
Bouzinova, EV2
Zhang, F1
Shao, J1
Zhong, Y1
Ye, L1
Meng, X1
Wang, H1
Finnell, JE1
Lombard, CM1
Padi, AR1
Moffitt, CM1
Wilson, LB1
Wood, CS1
Wood, SK1
Eiland, L1
Ramroop, J1
Hill, MN1
Manley, J1
McEwen, BS1
Briones, A1
Gagno, S1
Martisova, E1
Dobarro, M1
Aisa, B1
Solas, M1
Tordera, R1
Ramírez, M1
Berry, A1
Bellisario, V1
Tirassa, P1
Calza, A1
Bowens, N1
Heydendael, W1
Bhatnagar, S1
Barichello, T1
Milioli, G1
Generoso, JS1
Cipriano, AL1
Costa, CS1
Moreira, AP1
Vilela, MC1
Comim, CM1
Teixeira, AL1
Quevedo, J2
Réus, GZ1
Abelaira, HM1
Stringari, RB1
Fries, GR1
Kapczinski, F1
Møller-Nielsen, N1
Boedtkjer, DB1
Broegger, T1
Aalkjaer, C1
Matchkov, VV1
Zoratto, F1
Fiore, M1
Ali, SF1
Laviola, G2
Macrì, S2
Liu, J1
Guo, M1
Zhang, D1
Cheng, SY1
Liu, M1
Ding, J1
Scherer, PE1
Liu, F1
Lu, XY1
Ceci, C1
Canese, R1

Other Studies

56 other studies available for corticosterone and Anhedonia

ArticleYear
A single dose of ketamine cannot prevent protracted stress-induced anhedonia and neuroinflammation in rats.
    Stress (Amsterdam, Netherlands), 2022, Volume: 25, Issue:1

    Topics: Anhedonia; Animals; Antidepressive Agents; Carrier Proteins; Corticosterone; Depression; Disease Mod

2022
Swimming exercise strain-dependently affects maternal care and depression-related behaviors through gestational corticosterone and brain serotonin in postpartum dams.
    Brain research bulletin, 2022, 10-01, Volume: 188

    Topics: Anhedonia; Animals; Brain; Corticosterone; Depression; Depression, Postpartum; Female; Humans; Mater

2022
Antidepressive-Like Effect of
    BioMed research international, 2022, Volume: 2022

    Topics: Aegle; Anhedonia; Animals; Antidepressive Agents; Corticosterone; Depression; Disease Models, Animal

2022
Organic cation transporter 2 contributes to SSRI antidepressant efficacy by controlling tryptophan availability in the brain.
    Translational psychiatry, 2023, 09-29, Volume: 13, Issue:1

    Topics: Anhedonia; Animals; Antidepressive Agents; Brain; Corticosterone; Depressive Disorder, Major; Fluoxe

2023
Behavioral coping strategies predict tumor development and behavioral impairment after chronic social stress in mice.
    Physiology & behavior, 2020, 02-01, Volume: 214

    Topics: Adaptation, Psychological; Aggression; Anhedonia; Animals; Behavior, Animal; Corticosterone; Dominan

2020
Valproic acid administration exerts protective effects against stress-related anhedonia in rats.
    Journal of chemical neuroanatomy, 2020, Volume: 105

    Topics: Anhedonia; Animals; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Histone De

2020
(S)-norketamine and (2S,6S)-hydroxynorketamine exert potent antidepressant-like effects in a chronic corticosterone-induced mouse model of depression.
    Pharmacology, biochemistry, and behavior, 2020, Volume: 191

    Topics: Anhedonia; Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; Disease Mod

2020
Oleuropein Reverses Repeated Corticosterone-Induced Depressive-Like Behavior in mice: Evidence of Modulating Effect on Biogenic Amines.
    Scientific reports, 2020, 02-24, Volume: 10, Issue:1

    Topics: Anhedonia; Animals; Behavior, Animal; Biogenic Amines; Brain; Corticosterone; Depression; Disease Mo

2020
Bag-1 mediates glucocorticoid receptor trafficking to mitochondria after corticosterone stimulation: Potential role in regulating affective resilience.
    Journal of neurochemistry, 2021, Volume: 158, Issue:2

    Topics: Affect; Anhedonia; Animals; Corticosterone; Depression; DNA-Binding Proteins; Dose-Response Relation

2021
Indirect exposure to socially defeated conspecifics using recorded video activates the HPA axis and reduces reward sensitivity in mice.
    Scientific reports, 2020, 10-09, Volume: 10, Issue:1

    Topics: Anhedonia; Animals; Brain; Choice Behavior; Corticosterone; Depression; Disease Models, Animal; Empa

2020
Adult neurogenesis augmentation attenuates anhedonia and HPA axis dysregulation in a mouse model of chronic stress and depression.
    Psychoneuroendocrinology, 2021, Volume: 124

    Topics: Anhedonia; Animals; Behavior, Animal; Corticosterone; Depression; Depressive Disorder, Major; Diseas

2021
α9-nAChR knockout mice exhibit dysregulation of stress responses, affect and reward-related behaviour.
    Behavioural brain research, 2017, 06-15, Volume: 328

    Topics: Affect; Anhedonia; Animals; Anxiety; Arousal; Circadian Rhythm; Corticosterone; Male; Mice, 129 Stra

2017
Systemic N-terminal fragments of adrenocorticotropin reduce inflammation- and stress-induced anhedonia in rats.
    Psychoneuroendocrinology, 2017, Volume: 82

    Topics: Adrenocorticotropic Hormone; alpha-MSH; Anhedonia; Animals; Corticosterone; Depressive Disorder, Maj

2017
Impaired microglia fractalkine signaling affects stress reaction and coping style in mice.
    Behavioural brain research, 2017, 09-15, Volume: 334

    Topics: Adaptation, Psychological; Adrenocorticotropic Hormone; Anhedonia; Animals; Calcium-Binding Proteins

2017
Antidepressant and pro-neurogenic effects of agmatine in a mouse model of stress induced by chronic exposure to corticosterone.
    Progress in neuro-psychopharmacology & biological psychiatry, 2018, Feb-02, Volume: 81

    Topics: Agmatine; Anhedonia; Animals; Antidepressive Agents; Cell Proliferation; Corticosterone; Depressive

2018
Bifidobacterium pseudocatenulatum CECT 7765 Ameliorates Neuroendocrine Alterations Associated with an Exaggerated Stress Response and Anhedonia in Obese Mice.
    Molecular neurobiology, 2018, Volume: 55, Issue:6

    Topics: Adiposity; Anhedonia; Animals; Anxiety; Behavior, Animal; Bifidobacterium; Catecholamines; Corticost

2018
Mifepristone attenuates depression-like changes induced by chronic central administration of interleukin-1β in rats.
    Behavioural brain research, 2018, 07-16, Volume: 347

    Topics: Amygdala; Anhedonia; Animals; Antidepressive Agents; Corticosterone; Depressive Disorder; Disease Mo

2018
Maternal separation induces anhedonia in female heterozygous serotonin transporter knockout rats.
    Behavioural brain research, 2019, 01-01, Volume: 356

    Topics: Anhedonia; Animals; Behavior, Animal; Brain; Corticosterone; Depression; Depressive Disorder; Hetero

2019
Oxytocin administration prevents cellular aging caused by social isolation.
    Psychoneuroendocrinology, 2019, Volume: 103

    Topics: Anhedonia; Animals; Arvicolinae; Cellular Senescence; Corticosterone; Depression; Female; Glucocorti

2019
Reversal effect of Riparin IV in depression and anxiety caused by corticosterone chronic administration in mice.
    Pharmacology, biochemistry, and behavior, 2019, Volume: 180

    Topics: Amides; Anhedonia; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; B

2019
Group II metabotropic glutamate receptor blockade promotes stress resilience in mice.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2019, Volume: 44, Issue:10

    Topics: Amino Acids; Anhedonia; Animals; Behavior, Animal; Corticosterone; Electroshock; Escape Reaction; Ex

2019
Sex-dependent effects of early unstable post-natal environment on response to positive and negative stimuli in adult mice.
    Neuroscience, 2019, 08-10, Volume: 413

    Topics: Anhedonia; Animals; Behavior, Animal; Brain; Cocaine; Corticosterone; Disease Models, Animal; Dopami

2019
Antidepressant treatment outcome depends on the quality of the living environment: a pre-clinical investigation in mice.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Anhedonia; Animals; Antidepressive Agents; Behavior, Animal; Brain; Brain-Derived Neurotrophic Facto

2013
Gender differences in CMS and the effects of antidepressant venlafaxine in rats.
    Neurochemistry international, 2013, Volume: 63, Issue:6

    Topics: Anhedonia; Animals; Antidepressive Agents, Second-Generation; Body Weight; Corticosterone; Cyclohexa

2013
Pitx3 deficient mice as a genetic animal model of co-morbid depressive disorder and parkinsonism.
    Brain research, 2014, Mar-13, Volume: 1552

    Topics: Anhedonia; Animals; Antidepressive Agents; Brain; Comorbidity; Corticosterone; Depressive Disorder;

2014
Panax quinquefolium involves nitric oxide pathway in olfactory bulbectomy rat model.
    Physiology & behavior, 2014, Apr-22, Volume: 129

    Topics: Anhedonia; Animals; Arginine; Brain; Corticosterone; Depressive Disorder; Disease Models, Animal; Do

2014
Moderate treadmill exercise rescues anxiety and depression-like behavior as well as memory impairment in a rat model of posttraumatic stress disorder.
    Physiology & behavior, 2014, May-10, Volume: 130

    Topics: Anhedonia; Animals; Anxiety Disorders; Corticosterone; Depressive Disorder; Disease Models, Animal;

2014
Sex-specific disruptions in spatial memory and anhedonia in a "two hit" rat model correspond with alterations in hippocampal brain-derived neurotrophic factor expression and signaling.
    Hippocampus, 2014, Volume: 24, Issue:10

    Topics: Anhedonia; Animals; Anxiety; Brain-Derived Neurotrophic Factor; Corticosterone; Dietary Sucrose; Dis

2014
Neuropathic pain-induced depressive-like behavior and hippocampal neurogenesis and plasticity are dependent on TNFR1 signaling.
    Brain, behavior, and immunity, 2014, Volume: 41

    Topics: Anhedonia; Animals; Corticosterone; Depression; Drinking Behavior; Exploratory Behavior; Food Prefer

2014
Forebrain glucocorticoid receptor gene deletion attenuates behavioral changes and antidepressant responsiveness during chronic stress.
    Brain research, 2014, Oct-02, Volume: 1583

    Topics: Anhedonia; Animals; Antidepressive Agents; Chronic Disease; Circadian Rhythm; Corticosterone; Dietar

2014
GABAB(1) receptor subunit isoforms differentially regulate stress resilience.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Oct-21, Volume: 111, Issue:42

    Topics: Anhedonia; Animals; Behavior, Animal; Cell Proliferation; Corticosterone; Depression; Disease Models

2014
Systemic administration of oleoylethanolamide protects from neuroinflammation and anhedonia induced by LPS in rats.
    The international journal of neuropsychopharmacology, 2014, Dec-28, Volume: 18, Issue:6

    Topics: Amides; Anhedonia; Animals; Anti-Inflammatory Agents; Behavior, Animal; Body Temperature Regulation;

2014
Subchronic administration of riparin III induces antidepressive-like effects and increases BDNF levels in the mouse hippocampus.
    Fundamental & clinical pharmacology, 2015, Volume: 29, Issue:4

    Topics: Anhedonia; Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Benzamides; Brain-Derived Neur

2015
Agmatine, by Improving Neuroplasticity Markers and Inducing Nrf2, Prevents Corticosterone-Induced Depressive-Like Behavior in Mice.
    Molecular neurobiology, 2016, Volume: 53, Issue:5

    Topics: Agmatine; Anhedonia; Animals; Antidepressive Agents; Astrocytes; Behavior, Animal; Biomarkers; Corti

2016
Circadian variations in behaviors, BDNF and cell proliferation in depressive mice.
    Metabolic brain disease, 2015, Volume: 30, Issue:6

    Topics: Anhedonia; Animals; Behavior, Animal; Body Weight; Brain-Derived Neurotrophic Factor; Cell Prolifera

2015
Depressive-like behaviours and decreased dendritic branching in the medial prefrontal cortex of mice with tumors: A novel validated model of cancer-induced depression.
    Behavioural brain research, 2015, Nov-01, Volume: 294

    Topics: Anhedonia; Animals; Antidepressive Agents, Second-Generation; Cell Line, Tumor; Corticosterone; Dend

2015
Antidepressant-like activity and cardioprotective effects of fatty acid amide hydrolase inhibitor URB694 in socially stressed Wistar Kyoto rats.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2015, Volume: 25, Issue:11

    Topics: Amidohydrolases; Anhedonia; Animals; Antidepressive Agents; Arrhythmias, Cardiac; Biphenyl Compounds

2015
Time-dependent miR-16 serum fluctuations together with reciprocal changes in the expression level of miR-16 in mesocortical circuit contribute to stress resilient phenotype in chronic mild stress - An animal model of depression.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2016, Volume: 26, Issue:1

    Topics: Anhedonia; Animals; Biomarkers; Chronic Disease; Corticosterone; Depressive Disorder; Dietary Sucros

2016
Short photoperiod condition increases susceptibility to stress in adolescent male rats.
    Behavioural brain research, 2016, Mar-01, Volume: 300

    Topics: Aging; Anhedonia; Animals; Circadian Rhythm; Corticosterone; Disease Models, Animal; Disease Suscept

2016
High-Fat Diet Induced Anxiety and Anhedonia: Impact on Brain Homeostasis and Inflammation.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016, Volume: 41, Issue:7

    Topics: Anhedonia; Animals; Anxiety; Body Weight; Brain; Corticosterone; Diet, High-Fat; Disease Models, Ani

2016
Antidepressant-like effects of Sanyuansan in the mouse forced swim test, tail suspension test, and chronic mild stress model.
    The Kaohsiung journal of medical sciences, 2015, Volume: 31, Issue:12

    Topics: Anhedonia; Animals; Antidepressive Agents; Chronic Disease; Corticosterone; Disease Models, Animal;

2015
The neurogenic effects of an enriched environment and its protection against the behavioral consequences of chronic mild stress persistent after enrichment cessation in six-month-old female Balb/C mice.
    Behavioural brain research, 2016, Mar-15, Volume: 301

    Topics: Anhedonia; Animals; Blood Chemical Analysis; Bromodeoxyuridine; Cell Proliferation; Chronic Disease;

2016
Disturbed diurnal rhythm of three classical phase markers in the chronic mild stress rat model of depression.
    Neuroscience research, 2016, Volume: 110

    Topics: Anhedonia; Animals; Biomarkers; Body Temperature; Circadian Rhythm; Corticosterone; Depression; Eati

2016
Antidepressant-like Effects of LPM580153, A Novel Potent Triple Reuptake Inhibitor.
    Scientific reports, 2016, Apr-07, Volume: 6

    Topics: Anhedonia; Animals; Antidepressive Agents; Biological Transport; Blotting, Western; Brain-Derived Ne

2016
Physical versus psychological social stress in male rats reveals distinct cardiovascular, inflammatory and behavioral consequences.
    PloS one, 2017, Volume: 12, Issue:2

    Topics: Anhedonia; Animals; Behavior, Animal; Blood Pressure; Cardiovascular Diseases; Chromatography, High

2017
Chronic juvenile stress produces corticolimbic dendritic architectural remodeling and modulates emotional behavior in male and female rats.
    Psychoneuroendocrinology, 2012, Volume: 37, Issue:1

    Topics: Adaptation, Psychological; Amygdala; Anhedonia; Animals; Chronic Disease; Corticosterone; Dendrites;

2012
Stress-induced anhedonia is associated with an increase in Alzheimer's disease-related markers.
    British journal of pharmacology, 2012, Volume: 165, Issue:4

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Anhedonia; Animals;

2012
Social deprivation stress is a triggering factor for the emergence of anxiety- and depression-like behaviours and leads to reduced brain BDNF levels in C57BL/6J mice.
    Psychoneuroendocrinology, 2012, Volume: 37, Issue:6

    Topics: Adrenal Glands; Anhedonia; Animals; Anxiety; Behavior, Animal; Body Weight; Brain Chemistry; Brain-D

2012
Lack of elevations in glucocorticoids correlates with dysphoria-like behavior after repeated social defeat.
    Physiology & behavior, 2012, Feb-28, Volume: 105, Issue:4

    Topics: Adrenal Glands; Anhedonia; Animals; Anxiety; CA2 Region, Hippocampal; Corticosterone; Depression; Di

2012
Imipramine reverses depressive-like parameters in pneumococcal meningitis survivor rats.
    Journal of neural transmission (Vienna, Austria : 1996), 2012, Volume: 119, Issue:6

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Anhedonia; Animals; Antidepressive Agents, Tricyclic; B

2012
Memantine treatment reverses anhedonia, normalizes corticosterone levels and increases BDNF levels in the prefrontal cortex induced by chronic mild stress in rats.
    Metabolic brain disease, 2012, Volume: 27, Issue:2

    Topics: Adrenal Glands; Anhedonia; Animals; Brain Chemistry; Brain-Derived Neurotrophic Factor; Chronic Dise

2012
Chronic mild stress-induced depression-like symptoms in rats and abnormalities in catecholamine uptake in small arteries.
    Psychosomatic medicine, 2012, Volume: 74, Issue:3

    Topics: Analysis of Variance; Anhedonia; Animals; Arteries; Behavior, Animal; Blood Pressure; Catecholamines

2012
Neonatal tryptophan depletion and corticosterone supplementation modify emotional responses in adult male mice.
    Psychoneuroendocrinology, 2013, Volume: 38, Issue:1

    Topics: Anhedonia; Animals; Animals, Newborn; Animals, Suckling; Anxiety; Brain-Derived Neurotrophic Factor;

2013
Adiponectin is critical in determining susceptibility to depressive behaviors and has antidepressant-like activity.
    Proceedings of the National Academy of Sciences of the United States of America, 2012, Jul-24, Volume: 109, Issue:30

    Topics: Absorptiometry, Photon; Adiponectin; Anhedonia; Animals; Antibodies, Monoclonal; Blood Glucose; Cort

2012
Prenatal stress and peripubertal stimulation of the endocannabinoid system differentially regulate emotional responses and brain metabolism in mice.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: Anhedonia; Animals; Anxiety; Benzamides; Body Weight; Brain; Carbamates; Corticosterone; Drinking; E

2012
Not all stressors are equal: early social enrichment favors resilience to social but not physical stress in male mice.
    Hormones and behavior, 2013, Volume: 63, Issue:3

    Topics: Anhedonia; Animals; Animals, Newborn; Corticosterone; Female; Male; Maternal Behavior; Mice; Mice, I

2013