corticosterone has been researched along with Acute Post-Traumatic Stress Disorder in 140 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty days after ovariectomy, PTSD was induced by single prolonged stress (SPS) model." | 5.72 | Effect of treadmill exercise on serum corticosterone, serum and hippocampal BDNF, hippocampal apoptosis and anxiety behavior in an ovariectomized rat model of post-traumatic stress disorder (PTSD). ( Akhoundzadeh, K; Roshani, F; Shafia, S; Yakhkeshi, R, 2022) |
| "Oxytocin (OXT) is a neuropeptide that regulates sexual reproduction and social interaction and has recently earned specific attention due to its role in adjusting neurobiological and behavioral correlates of PTSD; however, the mechanism by which this is achieved remains unclear." | 5.48 | Effects of Oxytocin on Fear Memory and Neuroinflammation in a Rodent Model of Posttraumatic Stress Disorder. ( Chen, CC; Lin, CC; Liu, YP; Tzeng, NS; Wang, SC, 2018) |
| " Thus, we induced PTSD in pregnant rats by applying inescapable footshocks and then investigated the behavioral parameters similar to anxiety in offspring at prepubertal age, in addition to the plasma levels of maternal and offspring corticosterone and expression of glucocorticoid receptors (GR) in the offspring's hippocampus." | 4.02 | Anxiety-like behavior and neuroendocrine changes in offspring resulting from gestational post-traumatic stress disorder. ( Batista, TH; Chagas, LA; Elias, LLK; Ferrari, MS; Giusti-Paiva, A; Kalil-Cutti, B; Ribeiro, ACAF; Rojas, VCT; Vieira, JS; Vilela, FC, 2021) |
| " Here, using the predator scent model of PTSD in rats and a longitudinal design, we measure pre-trauma brain-wide neural circuit functional connectivity, behavioral and corticosterone responses to trauma exposure, and post-trauma anxiety." | 3.91 | Individual variability in behavior and functional networks predicts vulnerability using an animal model of PTSD. ( Bravo-Rivera, H; Dopfel, D; Ma, Y; Perez, PD; Quirk, GJ; Verbitsky, A; Zhang, N, 2019) |
| " Other studies demonstrate the roles of stathmin and corticosterone associated with fear- and anxiety-like behaviors in rodent models." | 3.91 | Affective profiling for anxiety-like behavior in a rodent model of mTBI. ( Ahlers, ST; Ciarlone, SL; Goodrich, JA; McCarron, RM; Norris, JN; Statz, JK; Tschiffely, AE; Walker, PB, 2019) |
| " We found high anxiety levels and poor maternal care along with reduced serum prolactin and increased corticosterone levels in dams following maternal trauma (MT)." | 3.83 | Effects of In utero environment and maternal behavior on neuroendocrine and behavioral alterations in a mouse model of prenatal trauma. ( Canneva, F; Distler, J; Freitag, CM; Frey, S; Funke, R; Golub, Y; Kratz, O; Moll, GH; Solati, J; von Hörsten, S, 2016) |
| "This study was designed to investigate the effectiveness of nisoldipine, an L-type voltage-sensitive calcium channel blocker, to ameliorate anxiety and fear response in a mouse model of post-traumatic stress disorder (PTSD)." | 3.83 | Investigating the role of nisoldipine in foot-shock-induced post-traumatic stress disorder in mice. ( Bali, A; Jaggi, AS; Singh, N; Verma, M, 2016) |
| "The correlation between the ACR and PTSD severity suggests that a flattened ACR may be a result of clinical symptoms." | 2.73 | Enhanced cortisol suppression in response to dexamethasone administration in traumatized veterans with and without posttraumatic stress disorder. ( de Kloet, CS; Geuze, E; Heijnen, CJ; Lentjes, EG; Vermetten, E; Westenberg, HG, 2007) |
| "MDD and PTSD patients present abnormalities in the HPA axis regulation, such as altered cortisol levels or failure to suppress cortisol release in the dexamethasone suppression test." | 2.72 | The Role of HPA Axis and Allopregnanolone on the Neurobiology of Major Depressive Disorders and PTSD. ( Almeida, FB; Barros, HMT; Pinna, G, 2021) |
| "Alcohol use disorder is a widespread mental illness characterized by periods of abstinence followed by recidivism, and stress is the primary trigger of relapse." | 2.58 | Sexual dimorphism in the neural impact of stress and alcohol. ( Bertholomey, ML; Logrip, ML; Milivojevic, V; Torregrossa, MM, 2018) |
| "Animal models of PTSD offer the opportunity to distinguish between biological and socio-cultural factors, which so often enter the discussion about gender differences in PTSD prevalence." | 2.47 | Gender differences in animal models of posttraumatic stress disorder. ( Cohen, H; Yehuda, R, 2011) |
| "Alcohol use disorders and other substance use disorders are extremely common among patients with posttraumatic stress disorder (PTSD)." | 2.41 | Substance use disorders in patients with posttraumatic stress disorder: a review of the literature. ( Jacobsen, LK; Kosten, TR; Southwick, SM, 2001) |
| "Corticosterone was reduced in benztropine-treated stressed males." | 1.91 | FKBP5 inhibitors modulate alcohol drinking and trauma-related behaviors in a model of comorbid post-traumatic stress and alcohol use disorder. ( Bradley, L; Carper, BA; Crawford, M; Cruz, B; Fain, K; Hirsch, S; Kirson, D; Kosten, TR; Nolen, T; Roberto, M; Vozella, V; Xu, JC; Zorrilla, EP, 2023) |
| "BDNF-HA2TAT/AAV therapeutically effects PTSD caused by SPS, with changes seen in plasma corticosterone and BDNF-TrkB pathways within the hippocampus; therefore, BDNF-HA2TAT/AAV may be a promising treatment for patients with PTSD." | 1.91 | Brain-Derived Neurotrophic Factor Delivered Intranasally Relieves Post-Traumatic Stress Disorder Symptoms Caused by a Single Prolonged Stress in Rats. ( Dang, Y; Deng, L; Ma, C; Zhang, H; Zhang, L, 2023) |
| "Treatment with fasudil and sertraline significantly restored the behavioral changes and normalized the corticosterone levels." | 1.91 | Investigations on Rho/ROCK signaling in post-traumatic stress disorder-like behavior in mice. ( Bali, A; Hanifa, M; Sree, AB, 2023) |
| "Posttraumatic stress disorder (PTSD) is a serious neuropsychiatric disorder that occurs after exposure to stressful, fearful, or troubling events." | 1.91 | Synergistic effects of combined therapy with cerebrolysin and enriched environment on anxiety-like behavior and spatial cognitive deficits in posttraumatic stress disorder-like mouse model. ( Farajdokht, F; Hosseini, L; Hosseini, MJ; Mahmoudi, J; Pasokh, A; Sadigh-Eteghad, S; Salehi-Pourmehr, H; Sandoghchian Shotorbani, S; Ziaee, M, 2023) |
| "Posttraumatic stress disorder (PTSD) is an anxiety disorder that occurs following exposure to somatic or psychotic trauma." | 1.72 | Prior short-term exercise prevents behavioral and biochemical abnormalities induced by single prolonged stress in a rat model of posttraumatic stress disorder. ( Afsari, R; Dehkordi, NS; Mirjalili, R; Rashidy-Pour, A; Shafia, S; Shokouh, E, 2022) |
| "Thus, resilience or susceptibility to PTSD was consistent with changes in glucocorticoid metabolism." | 1.72 | Mechanisms of Susceptibility and Resilience to PTSD: Role of Dopamine Metabolism and BDNF Expression in the Hippocampus. ( Downey, HF; Fedotova, JO; Ivleva, IS; Karpenko, MN; Kondashevskaya, MV; Manukhina, EB; Pashkov, AA; Shatilov, VA; Tseilikman, OB; Tseilikman, VE; Zhukov, MS, 2022) |
| "Twenty days after ovariectomy, PTSD was induced by single prolonged stress (SPS) model." | 1.72 | Effect of treadmill exercise on serum corticosterone, serum and hippocampal BDNF, hippocampal apoptosis and anxiety behavior in an ovariectomized rat model of post-traumatic stress disorder (PTSD). ( Akhoundzadeh, K; Roshani, F; Shafia, S; Yakhkeshi, R, 2022) |
| "Rats that exhibited PTSD-phenotype were characterized by blunted basal corticosterone pulsatility amplitude and a blunted corticosterone response to a stressor." | 1.62 | Is PTSD-Phenotype Associated with HPA-Axis Sensitivity? Feedback Inhibition and Other Modulating Factors of Glucocorticoid Signaling Dynamics. ( Cohen, H; Danan, D; Todder, D; Zohar, J, 2021) |
| "Interestingly, male rats in the MS3h-PTSD group showed decreased anxiety, but no similar changes were found in female rats, suggesting a degree of gender specificity in coping with stress after mild MS." | 1.62 | Maternal Separation-Induced Histone Acetylation Correlates with BDNF-Programmed Synaptic Changes in an Animal Model of PTSD with Sex Differences. ( Gou, L; Jiang, L; Kong, Y; Li, Q; Lian, B; Sun, H; Sun, L; Wang, Y; Zhang, X, 2021) |
| "Post-traumatic stress disorder (PTSD) is a psychological disorder affecting many around the world." | 1.62 | Non-selective orexin-receptor antagonist attenuates stress-re-stress-induced core PTSD-like symptoms in rats: Behavioural and neurochemical analyses. ( Krishnamurthy, S; Prajapati, SK, 2021) |
| "Post-traumatic stress disorder (PTSD) is a mental disorder that is linked with the onset of multiple anxiety-like behaviors." | 1.62 | The effects of laser stimulation at acupoint ST36 on anxiety-like behaviors and anterior cingulate cortex c-Fos expression in a rat post-traumatic stress disorder model. ( Liu, H; Liu, L; Liu, S; Qu, X; Shen, X; Yang, Y, 2021) |
| "Post-traumatic stress disorder (PTSD) is a stress-associated mental disorder characterized by an imbalance of neurotransmitters in response to traumatic events or fear." | 1.56 | Genistein Prevents Single Prolonged Stress-Induced Cognitive Impairment in a Post-Traumatic Stress Disorder Rat Model via Activation of the Serotonergic System. ( Choi, GM; Lee, B; Lee, H; Shim, I, 2020) |
| "Rats were divided into susceptible, PTSD(+), and resistant, PTSD(-), groups based on freezing duration during exposure to aversive context and the time spent in the central area in open field test one week after threefold stress experience (modified single prolonged stress)." | 1.56 | Individual susceptibility or resistance to posttraumatic stress disorder-like behaviours. ( Chmielewska, N; Kołosowska, K; Krząścik, P; Lehner, M; Maciejak, P; Płaźnik, A; Skórzewska, A; Sobolewska, A; Szyndler, J; Turzyńska, D; Wisłowska-Stanek, A, 2020) |
| "Risperidone and piracetam were found to be effective alone, while their high dose combination, produced potentiating effect in reversing the extinction deficit, behavioral alterations, altered cortical and hippocampal BDNF, IL-6, TNF-α, caspase-3, oxidative stress markers, and neurotransmitter levels." | 1.51 | Co-treatment of piracetam with risperidone rescued extinction deficits in experimental paradigms of post-traumatic stress disorder by restoring the physiological alterations in cortex and hippocampus. ( Akhtar, A; Bansal, Y; Kuhad, A; Sah, SP; Singh, R; Uniyal, A, 2019) |
| "Post-traumatic stress disorder (PTSD) has been associated with anxiety, memory impairments, enhanced fear, and hippocampal volume loss, although the relationship between these changes remain unknown." | 1.51 | New neurons restore structural and behavioral abnormalities in a rat model of PTSD. ( Cameron, HA; Martin, L; Padmanaban, V; Rhee, D; Schoenfeld, TJ; Smith, JA; Sonti, AN, 2019) |
| "Post traumatic stress disorder (PTSD) is one of the mental illness." | 1.51 | The anxiolytic-like effects of ginsenoside Rg2 on an animal model of PTSD. ( Gao, ZW; Ju, RL; Luo, M; Wu, SL; Zhang, WT, 2019) |
| "Post-traumatic stress disorder (PTSD) is a mental disorder characterized by symptoms of persistent anxiety arising after exposure to traumatic events." | 1.51 | Methyl-CpG binding protein 2 functional alterations provide vulnerability to develop behavioral and molecular features of post-traumatic stress disorder in male mice. ( Cosentino, L; De Filippis, B; Flor, H; Fuso, A; Lucarelli, M; Medici, V; Vigli, D, 2019) |
| "Repeated intake of caffeine aggravates PTSD-like symptoms in stress-exposed rats and induces PTSD-like symptoms in unstressed rats by altering the expression of glucocorticoid receptors." | 1.51 | Repeated caffeine administration aggravates post-traumatic stress disorder-like symptoms in rats. ( Dangi, DS; Krishnamurthy, S; Prajapati, SK, 2019) |
| "Posttraumatic stress disorder (PTSD) is associated with myocardial injury, but changes in coronary regulatory mechanisms in PTSD have not been investigated." | 1.48 | Posttraumatic Stress Disorder Disturbs Coronary Tone and Its Regulatory Mechanisms. ( Belyaeva, LE; Downey, HF; Fred Downey, H; Komelkova, MV; Kuzhel, OP; Lazuko, SS; Manukhina, EB; Tseilikman, OB; Tseilikman, VE, 2018) |
| "Post-traumatic stress disorder (PTSD) is a common consequence of exposure to a life-threatening event." | 1.48 | Influence of early stress on memory reconsolidation: Implications for post-traumatic stress disorder treatment. ( Benkahoul, A; Birmes, P; Ferry, B; Roullet, P; Villain, H, 2018) |
| "Post-traumatic stress disorder (PTSD) is the serious psychiatric disorder." | 1.48 | Anxiolytic-like effects of paeoniflorin in an animal model of post traumatic stress disorder. ( Chai, XM; Chen, JS; Fan, QH; He, JL; Liu, X; Qiu, ZK; Xiao, W; Ye, WH; Zeng, J, 2018) |
| "IHC alleviated both behavioral signs of PTSD and morphological evidence of adrenal cortex dystrophy." | 1.48 | Intermittent hypoxia improves behavioral and adrenal gland dysfunction induced by posttraumatic stress disorder in rats. ( Alliluev, AV; Downey, HF; Goryacheva, AV; Komelkova, MV; Kondashevskaya, MV; Lapshin, MS; Manukhina, EB; Platkovskii, PO; Tseilikman, OB; Tseilikman, VE, 2018) |
| "Oxytocin (OXT) is a neuropeptide that regulates sexual reproduction and social interaction and has recently earned specific attention due to its role in adjusting neurobiological and behavioral correlates of PTSD; however, the mechanism by which this is achieved remains unclear." | 1.48 | Effects of Oxytocin on Fear Memory and Neuroinflammation in a Rodent Model of Posttraumatic Stress Disorder. ( Chen, CC; Lin, CC; Liu, YP; Tzeng, NS; Wang, SC, 2018) |
| "Post-traumatic stress disorder (PTSD) is characterized by memory disturbances following trauma." | 1.46 | Predator odor evokes sex-independent stress responses in male and female Wistar rats and reduces phosphorylation of cyclic-adenosine monophosphate response element binding protein in the male, but not the female hippocampus. ( Barrileaux, B; Hajmurad, S; Homiack, D; Kreutz, MR; O'Cinneide, E; Schrader, LA; Stanley, M, 2017) |
| " We found that exposure to foot shock induced long-lasting behavioral deficiencies in mice, including freezing and anxiety-like behaviors, that were significantly ameliorated by the long-term administration of GLYX-13 (5 or 10 mg/kg)." | 1.43 | Anxiolytic effects of GLYX-13 in animal models of posttraumatic stress disorder-like behavior. ( Jin, ZL; Li, YF; Liu, JX; Liu, X; Ran, YH; Tang, Y; Xiong, J; Zhang, LM; Zheng, YY, 2016) |
| "The results showed that PTSD offsprings had lower body weights and OFT scores than control offsprings." | 1.43 | Epigenetic mechanism of maternal post-traumatic stress disorder in delayed rat offspring development: dysregulation of methylation and gene expression. ( Cao, B; Cao, J; Liang, XL; Liu, Q; Liu, S; Long, YJ; Peng, DZ; Wang, HY; Xie, WY; Zhang, H; Zhang, XG, 2016) |
| "Corticosterone pretreatment reduced the magnitude and incidence of avoidance." | 1.43 | Post-traumatic stress avoidance is attenuated by corticosterone and associated with brain levels of steroid receptor co-activator-1 in rats. ( Edwards, S; Farooq, MA; Gilpin, NW; Whitaker, AM, 2016) |
| "Post-traumatic stress disorder (PTSD), a highly debilitating neuropsychiatric disorder characterized by intense fear of trauma-related stimuli, often occurs in individuals that have only witnessed a traumatic event." | 1.43 | Vicarious social defeat stress: Bridging the gap between physical and emotional stress. ( Alcantara, LF; Bolaños-Guzmán, CA; Parise, EM; Sial, OK; Warren, BL, 2016) |
| "Post-traumatic stress disorder (PTSD) is a stress-related mental disorder caused by traumatic experiences." | 1.42 | Long-term effects of early adolescent stress: dysregulation of hypothalamic-pituitary-adrenal axis and central corticotropin releasing factor receptor 1 expression in adult male rats. ( Jiang, H; Li, C; Liu, D; Liu, Y; Lu, C; Pan, F; Yin, S, 2015) |
| "In the experiment, before the PTSD animal model was developed, Rg1 (10, 5, and 2." | 1.42 | Preventive effects of ginsenoside Rg1 on post-traumatic stress disorder (PTSD)-like behavior in male C57/B6 mice. ( Chen, L; Huang, Y; Ou Yang, L; Wang, Z; Zhao, Y; Zhu, K, 2015) |
| " The relative efficacy of pre versus post administration of corticosterone and high versus low dose of corticosterone on stress-induced exaggeration of innate fear response and stress-retarded body weight growth indicate that exogenous corticosterone administration within an appropriate time window and dosage are efficacious in diminishing traumatic stress induced pathophysiological processes." | 1.42 | Corticosterone mitigates the stress response in an animal model of PTSD. ( Benedek, D; Jia, M; Li, H; Li, X; Smerin, SE; Ursano, R; Xing, G; Zhang, L, 2015) |
| "SPS represents a preclinical model of PTSD-related sleep-wake and qEEG disturbances with underlying alterations in neurotransmitter systems known to modulate both sleep-wake architecture and the neural fear circuitry." | 1.42 | A rodent model of traumatic stress induces lasting sleep and quantitative electroencephalographic disturbances. ( Bubser, M; Conn, PJ; Gong, X; Gould, RW; Grannan, M; Ivarsson, M; Jones, CK; Lindsley, CW; Nedelcovych, MT; Thompson, AT; Zhan, X, 2015) |
| "Risperidone ameliorated increase in the activity of mitochondrial respiratory complex (I, II, IV, and V), decreases in the levels of mitochondrial membrane potential, cytochrome-C and caspase-9 in the hippocampus, hypothalamus, pre-frontal cortex, and amygdala." | 1.42 | Risperidone Attenuates Modified Stress-Re-stress Paradigm-Induced Mitochondrial Dysfunction and Apoptosis in Rats Exhibiting Post-traumatic Stress Disorder-Like Symptoms. ( Ahmad, A; Garabadu, D; Krishnamurthy, S, 2015) |
| "In a group of 92 veterans with PTSD, we observed significantly higher Clinician-Administered PTSD Scale and PTSD Checklist scores in E2+ individuals, as well as alterations in salivary cortisol levels." | 1.42 | ApoE2 Exaggerates PTSD-Related Behavioral, Cognitive, and Neuroendocrine Alterations. ( Bidiman, E; Johnson, LA; Marzulla, T; Raber, J; Wahbeh, H; Weber, S; Zuloaga, DG, 2015) |
| "Post-traumatic stress disorder (PTSD) is a condition which can develop from exposure to a severe traumatic event such as those occurring during wars or natural disasters." | 1.40 | Moderate treadmill exercise rescues anxiety and depression-like behavior as well as memory impairment in a rat model of posttraumatic stress disorder. ( Alkadhi, K; Allam, F; Dao, AT; Li, L; Patki, G; Salim, S; Solanki, N, 2014) |
| "Corticosterone treatment 1 h after PSS-exposure prevented anxiety and hyperarousal 7 d later in both sexes, confirming the GR involvement in the PSS behavioral response." | 1.40 | Expression profiling associates blood and brain glucocorticoid receptor signaling with trauma-related individual differences in both sexes. ( Buxbaum, JD; Cai, G; Cohen, H; Daskalakis, NP; Yehuda, R, 2014) |
| "Corticosterone levels were significantly suppressed by ketamine only in the exposed animals." | 1.40 | Immediate ketamine treatment does not prevent posttraumatic stress responses in an animal model for PTSD. ( Cohen, H; Juven-Wetzler, A; Kaplan, Z; Kohen, A; Porat, O; Zohar, J, 2014) |
| "Here we used a rodent model of PTSD in which rats repeatedly exposed to a stressor display heightened fear learning following auditory Pavlovian fear conditioning." | 1.40 | A ghrelin-growth hormone axis drives stress-induced vulnerability to enhanced fear. ( Burgos-Robles, A; Correia, SS; Goosens, KA; Liu, E; Meyer, RM, 2014) |
| "The management for post-traumatic stress disorder (PTSD) involves chronic administration of drugs." | 1.39 | Risperidone ameliorates post-traumatic stress disorder-like symptoms in modified stress re-stress model. ( Garabadu, D; Joy, KP; Krishnamurthy, S, 2013) |
| "Post-traumatic stress disorder (PTSD) is an anxiety disorder caused by traumatic experience, which affects a patient's quality of life and social stability." | 1.39 | Increased neuronal apoptosis in medial prefrontal cortex is accompanied with changes of Bcl-2 and Bax in a rat model of post-traumatic stress disorder. ( Han, F; Li, Y; Shi, Y, 2013) |
| "Post-traumatic stress disorder (PTSD) patients show cognitive deficits, but it is unclear whether these are a consequence of the pathology or a pre-existing factor of vulnerability to PTSD." | 1.38 | 7,8-dihydroxyflavone, a TrkB receptor agonist, blocks long-term spatial memory impairment caused by immobilization stress in rats. ( Andero, R; Armario, A; Daviu, N; Escorihuela, RM; Nadal, R, 2012) |
| "Posttraumatic stress disorder (PTSD) is characterized by a hypermnesia of the trauma and by a memory impairment that decreases the ability to restrict fear to the appropriate context." | 1.38 | Glucocorticoids can induce PTSD-like memory impairments in mice. ( Brayda-Bruno, L; Calandreau, L; Desmedt, A; Kaouane, N; Marighetto, A; Mons, N; Piazza, PV; Porte, Y; Vallée, M, 2012) |
| "Posttraumatic stress disorder (PTSD) is a debilitating disease, which affects 8-10% of the population exposed to traumatic events." | 1.38 | Susceptibility to PTSD-like behavior is mediated by corticotropin-releasing factor receptor type 2 levels in the bed nucleus of the stria terminalis. ( Chen, A; Gil, S; Kuperman, Y; Lebow, M; Neufeld-Cohen, A; Tsoory, M, 2012) |
| "In rodents, sleep deprivation (SD) negatively affects consolidation of hippocampus-dependent memories." | 1.38 | Post-exposure sleep deprivation facilitates correctly timed interactions between glucocorticoid and adrenergic systems, which attenuate traumatic stress responses. ( Cohen, H; Cohen, S; Kaplan, Z; Kozlovsky, N; Matar, MA; Zohar, J, 2012) |
| "Post-traumatic stress disorder (PTSD) is unique among psychiatric disorders since there is an explicit requirement for the presence of a well-defined precipitating environmental event." | 1.36 | DNA methylation in vulnerability to post-traumatic stress in rats: evidence for the role of the post-synaptic density protein Dlgap2. ( Ben-Shachar, D; Chertkow-Deutsher, Y; Cohen, H; Klein, E, 2010) |
| "Some of the symptoms of PTSD include persistent anxiety, exaggerated startle, cognitive impairments and increased sensitivity to yohimbine, an alpha(2)-adrenergic receptor antagonist." | 1.35 | Acute episodes of predator exposure in conjunction with chronic social instability as an animal model of post-traumatic stress disorder. ( Conrad, CD; Diamond, DM; Fleshner, M; Zoladz, PR, 2008) |
| "Post-traumatic stress disorder (PTSD) is associated with marked alterations in hypothalamic-pituitary adrenal (HPA) function." | 1.35 | Prenatal stress exacerbates the impact of an aversive procedure on the corticosterone response to stress in female rats. ( Darnaudéry, M; Louvart, H; Maccari, S; Vaiva, G, 2009) |
| "Alprazolam was associated with a significant attenuation of the HPA-response, suggesting a possible link between initial HPA-axis response disruption and the subsequent unfavorable outcomes." | 1.35 | Alprazolam treatment immediately after stress exposure interferes with the normal HPA-stress response and increases vulnerability to subsequent stress in an animal model of PTSD. ( Cohen, H; Kaplan, Z; Matar, MA; Zohar, J, 2009) |
| "Few animal models of PTSD have taken gender differences into account and have typically used male subjects." | 1.35 | Gender-related qualitative differences in baseline and post-stress anxiety responses are not reflected in the incidence of criterion-based PTSD-like behaviour patterns. ( Cohen, H; Kaplan, Z; Kozlovsky, N; Matar, MA; Mazor, A; Zohar, J, 2009) |
| "This study employed an animal model of PTSD to investigate the relationship between prevalence rates of distinct patterns of behavioural responses to predator stress, circulating levels of corticosterone and local levels of mRNA for BDNF, TrkB and two other neurotrophic factors in selected brain areas." | 1.34 | Long-term down-regulation of BDNF mRNA in rat hippocampal CA1 subregion correlates with PTSD-like behavioural stress response. ( Cohen, H; Kaplan, Z; Kotler, M; Kozlovsky, N; Matar, MA; Zohar, J, 2007) |
| "Post-traumatic stress disorder (PTSD) is a stress-related mental disorder caused by traumatic experience, and presents with characteristic symptoms, such as intrusive memories, a state of hyperarousal, and avoidance, that endure for years." | 1.34 | Glucocorticoid receptor activation is involved in producing abnormal phenotypes of single-prolonged stress rats: a putative post-traumatic stress disorder model. ( Harada, K; Hoshino, A; Kato, K; Kato, N; Kohda, K; Matsuoka, N; Morinobu, S; Motohashi, J; Yamaji, T, 2007) |
| "Post-traumatic stress disorder (PTSD) affects a vulnerable sub-population of individuals exposed to a traumatic event." | 1.33 | Long-term behavioural alterations in female rats after a single intense footshock followed by situational reminders. ( Darnaudéry, M; Ducrocq, F; Louvart, H; Maccari, S; Thomas, P, 2005) |
| "Post traumatic stress disorder (PTSD) is characterised by hyperarousal, anxiety and amnesic symptoms." | 1.32 | Endocrine, cognitive and hippocampal/cortical 5HT 1A/2A receptor changes evoked by a time-dependent sensitisation (TDS) stress model in rats. ( Brand, L; Harvey, BH; Naciti, C; Stein, DJ, 2003) |
| " Our results indicate that chronic administration of CRF into the basolateral amygdala may promote stress-induced grooming behavior in rats." | 1.32 | The effects of repeated intra-amygdala CRF injections on rat behavior and HPA axis function after stress. ( Daniels, WM; Richter, L; Stein, DJ, 2004) |
| "Due to the complexity of PTSD, animal models have been designed and advanced to address the role of psychosocial stressors in the etiology; however, the apparent role of genetics in susceptibility to PTSD-like behaviors in animals remains unexplored." | 1.31 | Genetic predisposition and the development of posttraumatic stress disorder in an animal model. ( Abend, S; Edwards, E; King, JA, 2001) |
| "Ohmefentanyl (OMF) is a new mu opioid receptor agonist with high affinity and selectivity, and possesses anesthetic activity." | 1.30 | [Effects of ohmefentanyl at anesthetic dose on plasma levels of corticosterone, cortisol and antidiuretic hormone in rats]. ( Chi, ZQ; Jin, WQ; Jin, XL; Li, GF; Zhou, DH, 1997) |
| "Posttraumatic stress disorder (PTSD) may occur in humans exposed chronically to stressors or after a single exposure to a traumatic event." | 1.29 | Delayed startle sensitization distinguishes rats exposed to one or three stress sessions: further evidence toward an animal model of PTSD. ( Natelson, BH; Ottenweller, JE; Servatius, RJ, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (2.86) | 18.2507 |
| 2000's | 27 (19.29) | 29.6817 |
| 2010's | 73 (52.14) | 24.3611 |
| 2020's | 36 (25.71) | 2.80 |
| Authors | Studies |
|---|---|
| Yakhkeshi, R | 1 |
| Roshani, F | 1 |
| Akhoundzadeh, K | 1 |
| Shafia, S | 2 |
| Tseilikman, V | 3 |
| Komelkova, M | 3 |
| Kondashevskaya, MV | 6 |
| Manukhina, E | 3 |
| Downey, HF | 7 |
| Chereshnev, V | 1 |
| Chereshneva, M | 1 |
| Platkovskii, P | 1 |
| Goryacheva, A | 1 |
| Pashkov, A | 1 |
| Fedotova, J | 1 |
| Tseilikman, O | 3 |
| Maltseva, N | 1 |
| Cherkasova, O | 2 |
| Steenblock, C | 1 |
| Bornstein, SR | 1 |
| Ettrich, B | 1 |
| Chrousos, GP | 1 |
| Ullmann, E | 1 |
| Komel'kova, MV | 2 |
| Tseilikman, VE | 6 |
| Tseilikman, OB | 6 |
| Artem'yeva, KA | 1 |
| Aleksankina, VV | 2 |
| Boltovskaya, MN | 1 |
| Sarapul'tsev, AP | 1 |
| Popkov, PN | 1 |
| Chereshneva, MV | 1 |
| Chereshnev, VA | 1 |
| Mirjalili, R | 1 |
| Shokouh, E | 1 |
| Dehkordi, NS | 1 |
| Afsari, R | 1 |
| Rashidy-Pour, A | 1 |
| Bardo, MT | 1 |
| Chandler, CM | 1 |
| Denehy, ED | 1 |
| Carper, BA | 4 |
| Prendergast, MA | 1 |
| Nolen, TL | 1 |
| Fulco, BCW | 1 |
| Klann, IP | 1 |
| Rodrigues, RF | 1 |
| Marzari, BN | 1 |
| Nogueira, CW | 1 |
| Cruz, B | 3 |
| Vozella, V | 3 |
| Xu, JC | 3 |
| Kirson, D | 3 |
| Hirsch, S | 3 |
| Nolen, T | 3 |
| Bradley, L | 3 |
| Fain, K | 3 |
| Crawford, M | 3 |
| Kosten, TR | 4 |
| Zorrilla, EP | 3 |
| Roberto, M | 3 |
| Pashkov, AA | 2 |
| Ivleva, IS | 2 |
| Karpenko, MN | 3 |
| Shatilov, VA | 2 |
| Zhukov, MS | 2 |
| Fedotova, JO | 3 |
| Manukhina, EB | 4 |
| Zhang, L | 2 |
| Deng, L | 1 |
| Ma, C | 1 |
| Zhang, H | 2 |
| Dang, Y | 1 |
| Sree, AB | 1 |
| Hanifa, M | 1 |
| Bali, A | 3 |
| Sanchís-Ollé, M | 1 |
| Belda, X | 5 |
| Gagliano, H | 2 |
| Visa, J | 1 |
| Nadal, R | 6 |
| Armario, A | 6 |
| Hosseini, L | 1 |
| Sadigh-Eteghad, S | 1 |
| Farajdokht, F | 1 |
| Salehi-Pourmehr, H | 1 |
| Pasokh, A | 1 |
| Ziaee, M | 1 |
| Sandoghchian Shotorbani, S | 1 |
| Hosseini, MJ | 1 |
| Mahmoudi, J | 1 |
| Novak, J | 1 |
| Maistrenko, VA | 1 |
| Lazuko, SS | 3 |
| Belyeva, LE | 1 |
| Kamel, M | 1 |
| Buhler, AV | 1 |
| Kovaleva, EG | 1 |
| Artemieva, KA | 1 |
| Kudelkina, VV | 1 |
| Kosyreva, AM | 1 |
| Areshidze, DA | 1 |
| Kozlova, MA | 1 |
| Mikhaleva, LM | 1 |
| Ben-Azu, B | 1 |
| Adebayo, OG | 1 |
| Moke, EG | 1 |
| Omogbiya, AI | 1 |
| Oritsemuelebi, B | 1 |
| Chidebe, EO | 1 |
| Umukoro, E | 2 |
| Nwangwa, EK | 1 |
| Etijoro, E | 1 |
| Mamudu, EJ | 1 |
| Chukwuma, C | 1 |
| Uniyal, A | 1 |
| Singh, R | 1 |
| Akhtar, A | 1 |
| Bansal, Y | 1 |
| Kuhad, A | 1 |
| Sah, SP | 1 |
| Prajapati, SK | 4 |
| Dangi, DS | 1 |
| Krishnamurthy, S | 6 |
| Shang, C | 1 |
| Guo, Y | 1 |
| Yao, JQ | 1 |
| Fang, XX | 1 |
| Sun, LJ | 1 |
| Jiang, XY | 1 |
| Ding, ZC | 1 |
| Ran, YH | 2 |
| Wang, HL | 1 |
| Zhang, LM | 2 |
| Li, YF | 2 |
| Singh, N | 2 |
| Garabadu, D | 3 |
| Merino, JJ | 1 |
| Muñetón-Gomez, V | 1 |
| Muñetón-Gómez, C | 1 |
| Pérez-Izquierdo, MÁ | 1 |
| Loscertales, M | 1 |
| Toledano Gasca, A | 1 |
| Skórzewska, A | 1 |
| Lehner, M | 1 |
| Wisłowska-Stanek, A | 1 |
| Turzyńska, D | 1 |
| Sobolewska, A | 1 |
| Krząścik, P | 1 |
| Szyndler, J | 1 |
| Maciejak, P | 1 |
| Chmielewska, N | 1 |
| Kołosowska, K | 1 |
| Płaźnik, A | 1 |
| Rybnikova, EA | 2 |
| Zenko, MY | 1 |
| Barysheva, VS | 1 |
| Vetrovoy, O | 1 |
| Lee, B | 1 |
| Choi, GM | 1 |
| Shim, I | 1 |
| Lee, H | 1 |
| Qu, X | 1 |
| Liu, H | 1 |
| Yang, Y | 1 |
| Liu, L | 1 |
| Shen, X | 1 |
| Liu, S | 2 |
| Lapshin, M | 1 |
| Alliluev, A | 1 |
| Karpenko, M | 1 |
| Pestereva, N | 1 |
| Kondashevskaya, M | 1 |
| Sarapultsev, A | 2 |
| Dremencov, E | 1 |
| Lin, CC | 4 |
| Cheng, PY | 1 |
| Liu, YP | 4 |
| Farbstein, D | 1 |
| Hollander, N | 1 |
| Peled, O | 1 |
| Apter, A | 1 |
| Fennig, S | 1 |
| Haberman, Y | 1 |
| Gitman, H | 1 |
| Yaniv, I | 1 |
| Shkalim, V | 1 |
| Pick, CG | 1 |
| Benaroya-Milshtein, N | 1 |
| Kaur, H | 1 |
| Kaur, R | 1 |
| Jaggi, AS | 2 |
| Kotomtsev, V | 1 |
| Platkovskiy, P | 1 |
| Fedorov, S | 1 |
| Sarapultsev, P | 1 |
| Tseilikman, D | 1 |
| Fuentes, S | 4 |
| Labad, J | 1 |
| Sun, H | 2 |
| Zhang, X | 1 |
| Kong, Y | 1 |
| Gou, L | 1 |
| Lian, B | 1 |
| Wang, Y | 1 |
| Jiang, L | 1 |
| Li, Q | 1 |
| Sun, L | 1 |
| Chagas, LA | 1 |
| Batista, TH | 1 |
| Ribeiro, ACAF | 1 |
| Ferrari, MS | 1 |
| Vieira, JS | 1 |
| Rojas, VCT | 1 |
| Kalil-Cutti, B | 1 |
| Elias, LLK | 1 |
| Giusti-Paiva, A | 1 |
| Vilela, FC | 1 |
| Fan, Z | 1 |
| Chen, J | 1 |
| Li, L | 2 |
| Wang, H | 1 |
| Gong, X | 2 |
| Xu, H | 1 |
| Wu, L | 1 |
| Yan, C | 1 |
| Almeida, FB | 1 |
| Pinna, G | 1 |
| Barros, HMT | 1 |
| Danan, D | 3 |
| Todder, D | 2 |
| Zohar, J | 20 |
| Cohen, H | 25 |
| Bhattacharjee, A | 1 |
| Homiack, D | 1 |
| O'Cinneide, E | 1 |
| Hajmurad, S | 1 |
| Barrileaux, B | 1 |
| Stanley, M | 1 |
| Kreutz, MR | 1 |
| Schrader, LA | 1 |
| Kuzhel, OP | 1 |
| Belyaeva, LE | 1 |
| Fred Downey, H | 1 |
| Komelkova, MV | 2 |
| Sillivan, SE | 1 |
| Joseph, NF | 1 |
| Jamieson, S | 1 |
| King, ML | 1 |
| Chévere-Torres, I | 1 |
| Fuentes, I | 1 |
| Shumyatsky, GP | 1 |
| Brantley, AF | 1 |
| Rumbaugh, G | 1 |
| Miller, CA | 1 |
| Pizzimenti, CL | 1 |
| Navis, TM | 1 |
| Lattal, KM | 1 |
| Matar, MA | 13 |
| Kaplan, Z | 17 |
| Vainer, E | 3 |
| Zeev, K | 1 |
| Mathé, AA | 2 |
| Villain, H | 1 |
| Benkahoul, A | 1 |
| Birmes, P | 1 |
| Ferry, B | 1 |
| Roullet, P | 1 |
| Qiu, ZK | 1 |
| He, JL | 1 |
| Liu, X | 2 |
| Zeng, J | 1 |
| Xiao, W | 1 |
| Fan, QH | 1 |
| Chai, XM | 1 |
| Ye, WH | 1 |
| Chen, JS | 1 |
| Van Camp, G | 1 |
| Cigalotti, J | 1 |
| Bouwalerh, H | 1 |
| Mairesse, J | 1 |
| Gatta, E | 1 |
| Palanza, P | 1 |
| Maccari, S | 3 |
| Morley-Fletcher, S | 1 |
| Daviu, N | 3 |
| Goryacheva, AV | 1 |
| Lapshin, MS | 2 |
| Platkovskii, PO | 1 |
| Alliluev, AV | 1 |
| Huang, KL | 1 |
| Tung, CS | 2 |
| Logrip, ML | 1 |
| Milivojevic, V | 1 |
| Bertholomey, ML | 1 |
| Torregrossa, MM | 1 |
| Wang, SC | 1 |
| Chen, CC | 1 |
| Tzeng, NS | 1 |
| Conoscenti, MA | 1 |
| Williams, NM | 1 |
| Turcotte, LP | 1 |
| Minor, TR | 1 |
| Fanselow, MS | 3 |
| Schoenfeld, TJ | 1 |
| Rhee, D | 1 |
| Martin, L | 1 |
| Smith, JA | 1 |
| Sonti, AN | 1 |
| Padmanaban, V | 1 |
| Cameron, HA | 1 |
| Statz, JK | 1 |
| Ciarlone, SL | 1 |
| Goodrich, JA | 1 |
| McCarron, RM | 1 |
| Walker, PB | 1 |
| Norris, JN | 1 |
| Ahlers, ST | 1 |
| Tschiffely, AE | 1 |
| Gao, ZW | 1 |
| Ju, RL | 1 |
| Luo, M | 1 |
| Wu, SL | 1 |
| Zhang, WT | 1 |
| Dopfel, D | 1 |
| Perez, PD | 1 |
| Verbitsky, A | 1 |
| Bravo-Rivera, H | 1 |
| Ma, Y | 1 |
| Quirk, GJ | 1 |
| Zhang, N | 1 |
| Cosentino, L | 1 |
| Vigli, D | 1 |
| Medici, V | 1 |
| Flor, H | 1 |
| Lucarelli, M | 1 |
| Fuso, A | 1 |
| De Filippis, B | 1 |
| Joy, KP | 1 |
| Meyer, RM | 1 |
| Burgos-Robles, A | 1 |
| Liu, E | 1 |
| Correia, SS | 1 |
| Goosens, KA | 1 |
| Poulos, AM | 1 |
| Reger, M | 1 |
| Mehta, N | 1 |
| Zhuravka, I | 1 |
| Sterlace, SS | 1 |
| Gannam, C | 1 |
| Hovda, DA | 1 |
| Giza, CC | 1 |
| Juven-Wetzler, A | 1 |
| Kohen, A | 1 |
| Porat, O | 1 |
| Moore, NL | 1 |
| Gauchan, S | 1 |
| Genovese, RF | 1 |
| Ryoke, R | 1 |
| Yamada, K | 1 |
| Ichitani, Y | 1 |
| Patki, G | 3 |
| Allam, F | 1 |
| Solanki, N | 3 |
| Dao, AT | 1 |
| Alkadhi, K | 1 |
| Salim, S | 3 |
| Pivina, SG | 5 |
| Akulova, VK | 3 |
| Rakitskaya, VV | 2 |
| Ordyan, NE | 3 |
| Daskalakis, NP | 1 |
| Cai, G | 1 |
| Buxbaum, JD | 1 |
| Yehuda, R | 2 |
| Jia, M | 1 |
| Smerin, SE | 1 |
| Xing, G | 1 |
| Li, X | 1 |
| Benedek, D | 1 |
| Ursano, R | 1 |
| Li, H | 1 |
| Alkadhi, I | 1 |
| Atrooz, F | 1 |
| Reznikov, R | 1 |
| Diwan, M | 1 |
| Nobrega, JN | 1 |
| Hamani, C | 1 |
| Nedelcovych, MT | 1 |
| Gould, RW | 1 |
| Zhan, X | 1 |
| Bubser, M | 1 |
| Grannan, M | 1 |
| Thompson, AT | 1 |
| Ivarsson, M | 1 |
| Lindsley, CW | 1 |
| Conn, PJ | 1 |
| Jones, CK | 1 |
| Kao, CY | 1 |
| Stalla, G | 1 |
| Stalla, J | 1 |
| Wotjak, CT | 1 |
| Anderzhanova, E | 1 |
| Ahmad, A | 1 |
| Fenchel, D | 1 |
| Levkovitz, Y | 1 |
| Keller, SM | 1 |
| Schreiber, WB | 1 |
| Stanfield, BR | 1 |
| Knox, D | 1 |
| Johnson, LA | 1 |
| Zuloaga, DG | 1 |
| Bidiman, E | 1 |
| Marzulla, T | 1 |
| Weber, S | 1 |
| Wahbeh, H | 1 |
| Raber, J | 1 |
| Li, C | 1 |
| Liu, Y | 1 |
| Yin, S | 1 |
| Lu, C | 1 |
| Liu, D | 1 |
| Jiang, H | 1 |
| Pan, F | 1 |
| Ordjan, NE | 1 |
| Mironova, VI | 2 |
| Rakitskaia, VV | 2 |
| Wang, Z | 1 |
| Zhu, K | 1 |
| Chen, L | 1 |
| Ou Yang, L | 1 |
| Huang, Y | 1 |
| Zhao, Y | 1 |
| Perusini, JN | 1 |
| Meyer, EM | 1 |
| Long, VA | 1 |
| Rau, V | 1 |
| Nocera, N | 1 |
| Avershal, J | 1 |
| Maksymetz, J | 1 |
| Spigelman, I | 1 |
| Whitaker, AM | 1 |
| Farooq, MA | 1 |
| Edwards, S | 1 |
| Gilpin, NW | 1 |
| Sial, OK | 1 |
| Warren, BL | 1 |
| Alcantara, LF | 1 |
| Parise, EM | 1 |
| Bolaños-Guzmán, CA | 1 |
| Finsterwald, C | 1 |
| Steinmetz, AB | 1 |
| Travaglia, A | 1 |
| Alberini, CM | 1 |
| Verma, M | 1 |
| Perrine, SA | 1 |
| Eagle, AL | 1 |
| George, SA | 1 |
| Mulo, K | 1 |
| Kohler, RJ | 1 |
| Gerard, J | 1 |
| Harutyunyan, A | 1 |
| Hool, SM | 1 |
| Susick, LL | 1 |
| Schneider, BL | 1 |
| Ghoddoussi, F | 1 |
| Galloway, MP | 1 |
| Liberzon, I | 2 |
| Conti, AC | 1 |
| Golub, Y | 1 |
| Canneva, F | 1 |
| Funke, R | 1 |
| Frey, S | 1 |
| Distler, J | 1 |
| von Hörsten, S | 1 |
| Freitag, CM | 1 |
| Kratz, O | 1 |
| Moll, GH | 1 |
| Solati, J | 1 |
| Jin, ZL | 1 |
| Liu, JX | 1 |
| Zheng, YY | 1 |
| Tang, Y | 1 |
| Xiong, J | 1 |
| Lin, PH | 1 |
| Huang, CL | 1 |
| Tseylikman, OB | 1 |
| Kozochkin, DA | 1 |
| Kuzina, OV | 1 |
| Golodniy, SV | 1 |
| Tseylikman, VE | 1 |
| Zhang, XG | 1 |
| Liang, XL | 1 |
| Liu, Q | 1 |
| Wang, HY | 1 |
| Cao, B | 1 |
| Cao, J | 1 |
| Long, YJ | 1 |
| Xie, WY | 1 |
| Peng, DZ | 1 |
| Cohen, S | 2 |
| Ifergane, G | 1 |
| Lewitus, GM | 1 |
| Schwartz, M | 1 |
| Zoladz, PR | 1 |
| Conrad, CD | 1 |
| Fleshner, M | 1 |
| Diamond, DM | 1 |
| Buskila, D | 1 |
| Samoilov, MO | 1 |
| Tyul'kova, EI | 1 |
| Vataeva, LA | 1 |
| Abritalin, EY | 1 |
| Kolchev, AI | 1 |
| Kozlovsky, N | 10 |
| Louvart, H | 2 |
| Vaiva, G | 1 |
| Darnaudéry, M | 2 |
| Bazak, N | 1 |
| Matar, M | 2 |
| Golan, H | 1 |
| Richter-Levin, G | 1 |
| Chertkow-Deutsher, Y | 1 |
| Klein, E | 1 |
| Ben-Shachar, D | 1 |
| Gidron, Y | 1 |
| McGuire, J | 1 |
| Herman, JP | 1 |
| Horn, PS | 1 |
| Sallee, FR | 1 |
| Sah, R | 1 |
| Andero, R | 1 |
| Escorihuela, RM | 1 |
| Bakshi, VP | 1 |
| Alsene, KM | 1 |
| Roseboom, PH | 1 |
| Connors, EE | 1 |
| Kaouane, N | 1 |
| Porte, Y | 1 |
| Vallée, M | 1 |
| Brayda-Bruno, L | 1 |
| Mons, N | 1 |
| Calandreau, L | 1 |
| Marighetto, A | 1 |
| Piazza, PV | 1 |
| Desmedt, A | 1 |
| Ordian, NE | 1 |
| Fedotova, IuO | 1 |
| Rao, RP | 1 |
| Anilkumar, S | 1 |
| McEwen, BS | 1 |
| Chattarji, S | 1 |
| Lebow, M | 1 |
| Neufeld-Cohen, A | 1 |
| Kuperman, Y | 1 |
| Tsoory, M | 1 |
| Gil, S | 1 |
| Chen, A | 1 |
| Viviani, D | 1 |
| Haegler, P | 1 |
| Strasser, DS | 1 |
| Steiner, MA | 1 |
| Serova, LI | 1 |
| Tillinger, A | 1 |
| Alaluf, LG | 1 |
| Laukova, M | 1 |
| Keegan, K | 1 |
| Sabban, EL | 1 |
| Li, Y | 1 |
| Han, F | 1 |
| Shi, Y | 1 |
| Harvey, BH | 2 |
| Naciti, C | 1 |
| Brand, L | 2 |
| Stein, DJ | 3 |
| Oosthuizen, F | 1 |
| Wegener, G | 1 |
| Daniels, WM | 1 |
| Richter, L | 1 |
| Ducrocq, F | 1 |
| Thomas, P | 1 |
| Maayan, R | 1 |
| Touati-Werner, D | 1 |
| A Matar, M | 1 |
| Loewenthal, U | 1 |
| Weizman, R | 1 |
| Kotler, M | 2 |
| de Kloet, CS | 1 |
| Vermetten, E | 1 |
| Heijnen, CJ | 1 |
| Geuze, E | 1 |
| Lentjes, EG | 1 |
| Westenberg, HG | 1 |
| Diehl, LA | 1 |
| Silveira, PP | 1 |
| Leite, MC | 1 |
| Crema, LM | 1 |
| Portella, AK | 1 |
| Billodre, MN | 1 |
| Nunes, E | 1 |
| Henriques, TP | 1 |
| Fidelix-da-Silva, LB | 1 |
| Heis, MD | 1 |
| Gonçalves, CA | 1 |
| Quillfeldt, JA | 1 |
| Dalmaz, C | 1 |
| Kohda, K | 1 |
| Harada, K | 1 |
| Kato, K | 1 |
| Hoshino, A | 1 |
| Motohashi, J | 1 |
| Yamaji, T | 1 |
| Morinobu, S | 1 |
| Matsuoka, N | 1 |
| Kato, N | 1 |
| Geva, AB | 1 |
| Mazor, A | 1 |
| Rasmussen, DD | 1 |
| Crites, NJ | 1 |
| Burke, BL | 1 |
| Servatius, RJ | 1 |
| Ottenweller, JE | 1 |
| Natelson, BH | 1 |
| Antelman, SM | 1 |
| Caggiula, AR | 1 |
| Gershon, S | 1 |
| Edwards, DJ | 1 |
| Austin, MC | 1 |
| Kiss, S | 1 |
| Kocan, D | 1 |
| Krstov, M | 1 |
| Young, EA | 1 |
| Jin, XL | 1 |
| Jin, WQ | 1 |
| Zhou, DH | 1 |
| Li, GF | 1 |
| Chi, ZQ | 1 |
| Heim, C | 1 |
| Nemeroff, CB | 1 |
| Jacobsen, LK | 1 |
| Southwick, SM | 1 |
| King, JA | 1 |
| Abend, S | 1 |
| Edwards, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Building Resilience Among Women: a Social Neuroscience Approach for the Prevention of Intimate Partner Violence Consequences[NCT03623555] | 172 participants (Anticipated) | Observational | 2019-03-01 | Recruiting | |||
| The Efficacy of a Single Dose IV Hydrocortisone Given Within 6 Hours of Exposure to a Traumatic Event in PTSD Prevention[NCT00855270] | 120 participants (Anticipated) | Interventional | 2009-04-30 | Recruiting | |||
| The Efficacy of the Proximate Administration of Oxytocin After a Traumatic Event in Preventing the Development of Post Traumatic Stress Disorder[NCT01039766] | 24 participants (Anticipated) | Interventional | 2010-02-28 | Recruiting | |||
| The Efficiency of Eye Movement Desensitization and Reprocessing (EMDR) for the Treatment of Substance Use Disorders: A Randomized Controlled Trial[NCT03114423] | 60 participants (Anticipated) | Interventional | 2017-04-07 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 reviews available for corticosterone and Acute Post-Traumatic Stress Disorder
| Article | Year |
|---|---|
The Role of HPA Axis and Allopregnanolone on the Neurobiology of Major Depressive Disorders and PTSD.
Topics: Adaptation, Physiological; Animals; Antidepressive Agents; Chronic Disease; Corticosterone; Depressi | 2021 |
Sexual dimorphism in the neural impact of stress and alcohol.
Topics: Alcoholism; Animals; Anxiety Disorders; Brain; Corticosterone; Female; Humans; Hydrocortisone; Male; | 2018 |
Stress-induced sensitization: the hypothalamic-pituitary-adrenal axis and beyond.
Topics: Adrenocorticotropic Hormone; Animals; Catecholamines; Central Nervous System Sensitization; Corticos | 2015 |
Induction and Expression of Fear Sensitization Caused by Acute Traumatic Stress.
Topics: Acute Disease; Animals; Basolateral Nuclear Complex; Corticosterone; Fear; Humans; Stress Disorders, | 2016 |
Gender differences in animal models of posttraumatic stress disorder.
Topics: Adrenal Glands; Androgens; Animals; Corticosterone; Disease Models, Animal; Estrogens; Female; Human | 2011 |
Stressor-induced oscillation. A possible model of the bidirectional symptoms in PTSD.
Topics: Animals; Brain; Corticosterone; Disease Models, Animal; Dopamine; Humans; Models, Psychological; Rat | 1997 |
The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies.
Topics: Adrenocorticotropic Hormone; Adult; Animals; Anxiety Disorders; Anxiety, Separation; Brain; Child; C | 2001 |
Substance use disorders in patients with posttraumatic stress disorder: a review of the literature.
Topics: Adult; Animals; Arousal; Comorbidity; Corticosterone; Corticotropin-Releasing Hormone; Diagnosis, Du | 2001 |
1 trial available for corticosterone and Acute Post-Traumatic Stress Disorder
| Article | Year |
|---|---|
Enhanced cortisol suppression in response to dexamethasone administration in traumatized veterans with and without posttraumatic stress disorder.
Topics: Adaptation, Physiological; Adrenocorticotropic Hormone; Adult; Analysis of Variance; Area Under Curv | 2007 |
131 other studies available for corticosterone and Acute Post-Traumatic Stress Disorder
| Article | Year |
|---|---|
Effect of treadmill exercise on serum corticosterone, serum and hippocampal BDNF, hippocampal apoptosis and anxiety behavior in an ovariectomized rat model of post-traumatic stress disorder (PTSD).
Topics: Animals; Anxiety; Apoptosis; Brain-Derived Neurotrophic Factor; Corticosterone; Disease Models, Anim | 2022 |
A Rat Model of Post-Traumatic Stress Syndrome Causes Phenotype-Associated Morphological Changes and Hypofunction of the Adrenal Gland.
Topics: Adrenal Glands; Animals; Case-Control Studies; Chromatography, High Pressure Liquid; Corticosterone; | 2021 |
New Morphofunctional Criteria for Resistance Profile in Post-Traumatic Stress Disorder Models as Adrenal Dysfunction Trigger.
Topics: Animals; Corticosterone; Disease Models, Animal; Rats; Rats, Wistar; Stress Disorders, Post-Traumati | 2021 |
Prior short-term exercise prevents behavioral and biochemical abnormalities induced by single prolonged stress in a rat model of posttraumatic stress disorder.
Topics: Animals; Brain-Derived Neurotrophic Factor; Corticosterone; Disease Models, Animal; Female; Hippocam | 2022 |
Effect of the glucocorticoid receptor antagonist PT150 on acquisition and escalation of fentanyl self-administration following early-life stress.
Topics: Animals; Corticosterone; Female; Fentanyl; Male; Rats; Rats, Sprague-Dawley; Receptors, Glucocortico | 2023 |
Social-single prolonged stress as an ether-free candidate animal model of post-traumatic stress disorder: Female and male outcomings.
Topics: Animals; Corticosterone; Dexamethasone; Disease Models, Animal; Ether; Female; Hippocampus; Male; Ra | 2022 |
FKBP5 inhibitors modulate alcohol drinking and trauma-related behaviors in a model of comorbid post-traumatic stress and alcohol use disorder.
Topics: Alcohol Drinking; Alcoholism; Animals; Benztropine; Comorbidity; Corticosterone; Male; Rats; Stress | 2023 |
FKBP5 inhibitors modulate alcohol drinking and trauma-related behaviors in a model of comorbid post-traumatic stress and alcohol use disorder.
Topics: Alcohol Drinking; Alcoholism; Animals; Benztropine; Comorbidity; Corticosterone; Male; Rats; Stress | 2023 |
FKBP5 inhibitors modulate alcohol drinking and trauma-related behaviors in a model of comorbid post-traumatic stress and alcohol use disorder.
Topics: Alcohol Drinking; Alcoholism; Animals; Benztropine; Comorbidity; Corticosterone; Male; Rats; Stress | 2023 |
FKBP5 inhibitors modulate alcohol drinking and trauma-related behaviors in a model of comorbid post-traumatic stress and alcohol use disorder.
Topics: Alcohol Drinking; Alcoholism; Animals; Benztropine; Comorbidity; Corticosterone; Male; Rats; Stress | 2023 |
FKBP5 inhibitors modulate alcohol drinking and trauma-related behaviors in a model of comorbid post-traumatic stress and alcohol use disorder.
Topics: Alcohol Drinking; Alcoholism; Animals; Benztropine; Comorbidity; Corticosterone; Male; Rats; Stress | 2023 |
FKBP5 inhibitors modulate alcohol drinking and trauma-related behaviors in a model of comorbid post-traumatic stress and alcohol use disorder.
Topics: Alcohol Drinking; Alcoholism; Animals; Benztropine; Comorbidity; Corticosterone; Male; Rats; Stress | 2023 |
FKBP5 inhibitors modulate alcohol drinking and trauma-related behaviors in a model of comorbid post-traumatic stress and alcohol use disorder.
Topics: Alcohol Drinking; Alcoholism; Animals; Benztropine; Comorbidity; Corticosterone; Male; Rats; Stress | 2023 |
FKBP5 inhibitors modulate alcohol drinking and trauma-related behaviors in a model of comorbid post-traumatic stress and alcohol use disorder.
Topics: Alcohol Drinking; Alcoholism; Animals; Benztropine; Comorbidity; Corticosterone; Male; Rats; Stress | 2023 |
FKBP5 inhibitors modulate alcohol drinking and trauma-related behaviors in a model of comorbid post-traumatic stress and alcohol use disorder.
Topics: Alcohol Drinking; Alcoholism; Animals; Benztropine; Comorbidity; Corticosterone; Male; Rats; Stress | 2023 |
Mechanisms of Susceptibility and Resilience to PTSD: Role of Dopamine Metabolism and BDNF Expression in the Hippocampus.
Topics: Animals; Corticosterone; Disease Models, Animal; Dopamine; Hexobarbital; Hippocampus; Rats; Stress D | 2022 |
Mechanisms of Susceptibility and Resilience to PTSD: Role of Dopamine Metabolism and BDNF Expression in the Hippocampus.
Topics: Animals; Corticosterone; Disease Models, Animal; Dopamine; Hexobarbital; Hippocampus; Rats; Stress D | 2022 |
Mechanisms of Susceptibility and Resilience to PTSD: Role of Dopamine Metabolism and BDNF Expression in the Hippocampus.
Topics: Animals; Corticosterone; Disease Models, Animal; Dopamine; Hexobarbital; Hippocampus; Rats; Stress D | 2022 |
Mechanisms of Susceptibility and Resilience to PTSD: Role of Dopamine Metabolism and BDNF Expression in the Hippocampus.
Topics: Animals; Corticosterone; Disease Models, Animal; Dopamine; Hexobarbital; Hippocampus; Rats; Stress D | 2022 |
Brain-Derived Neurotrophic Factor Delivered Intranasally Relieves Post-Traumatic Stress Disorder Symptoms Caused by a Single Prolonged Stress in Rats.
Topics: Animals; Anxiety; Brain-Derived Neurotrophic Factor; Corticosterone; Disease Models, Animal; Hippoca | 2023 |
Investigations on Rho/ROCK signaling in post-traumatic stress disorder-like behavior in mice.
Topics: Animals; Anxiety; Corticosterone; Disease Models, Animal; Mice; Sertraline; Stress Disorders, Post-T | 2023 |
Animal models of PTSD: Comparison of the neuroendocrine and behavioral sequelae of immobilization and a modified single prolonged stress procedure that includes immobilization.
Topics: Animals; Corticosterone; Ethers; Extinction, Psychological; Fear; Hypothalamo-Hypophyseal System; Ma | 2023 |
Synergistic effects of combined therapy with cerebrolysin and enriched environment on anxiety-like behavior and spatial cognitive deficits in posttraumatic stress disorder-like mouse model.
Topics: Amino Acids; Animals; Anxiety; Cognition; Corticosterone; Disease Models, Animal; Hippocampus; Memor | 2023 |
Resistance to Resveratrol Treatment in Experimental PTSD Is Associated with Abnormalities in Hepatic Metabolism of Glucocorticoids.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenases; Animals; Cortico | 2023 |
Role of Neurohumoral Imbalance at Post-Traumatic Stress Disorder in the Antitumor Immune Response. Experimental Study.
Topics: Animals; Corticosterone; Cytokines; Immunity; Male; Melanoma, Experimental; Mice; Stress Disorders, | 2023 |
Geraniol attenuates behavioral and neurochemical impairments by inhibitions of HPA-axis and oxido-inflammatory perturbations in mice exposed to post-traumatic stress disorder.
Topics: Acetylcholinesterase; Animals; Corticosterone; Disease Models, Animal; Fluoxetine; Hippocampus; Hypo | 2023 |
Co-treatment of piracetam with risperidone rescued extinction deficits in experimental paradigms of post-traumatic stress disorder by restoring the physiological alterations in cortex and hippocampus.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Corticosterone; Disease Models, Animal; Drug Synerg | 2019 |
Repeated caffeine administration aggravates post-traumatic stress disorder-like symptoms in rats.
Topics: Amygdala; Animals; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Corticosterone; Hi | 2019 |
Rapid anti-PTSD-like activity of the TSPO agonist YL-IPA08: Emphasis on brain GABA, neurosteroids and HPA axis function.
Topics: Animals; Behavior, Animal; Carrier Proteins; Corticosterone; Disease Models, Animal; gamma-Aminobuty | 2020 |
A novel stress re-stress model: modification of re-stressor cue induces long-lasting post-traumatic stress disorder-like symptoms in rats.
Topics: Animals; Anxiety; Behavior, Animal; Cognitive Dysfunction; Corticosterone; Cues; Depression; Disease | 2020 |
Hippocampal CCR5/RANTES Elevations in a Rodent Model of Post-Traumatic Stress Disorder: Maraviroc (a CCR5 Antagonist) Increases Corticosterone Levels and Enhances Fear Memory Consolidation.
Topics: Adrenal Cortex Hormones; Animals; CCR5 Receptor Antagonists; Chemokine CCL5; Corticosterone; Disease | 2020 |
Individual susceptibility or resistance to posttraumatic stress disorder-like behaviours.
Topics: Amygdala; Animals; Brain; Corticosterone; Corticotropin-Releasing Hormone; Dentate Gyrus; Disease Mo | 2020 |
Acclimatization to Middle Attitude Hypoxia Masks the Symptoms of Experimental Posttraumatic Stress Disorder, but Does Not Affect Its Pathogenetic Mechanisms.
Topics: Acclimatization; Altitude; Altitude Sickness; Animals; Corticosterone; Disease Models, Animal; Hypot | 2020 |
Genistein Prevents Single Prolonged Stress-Induced Cognitive Impairment in a Post-Traumatic Stress Disorder Rat Model via Activation of the Serotonergic System.
Topics: Animals; Cognition; Cognitive Dysfunction; Corticosterone; Disease Models, Animal; Genistein; Hippoc | 2020 |
The effects of laser stimulation at acupoint ST36 on anxiety-like behaviors and anterior cingulate cortex c-Fos expression in a rat post-traumatic stress disorder model.
Topics: Acupuncture Points; Animals; Anxiety; Behavior, Animal; Cell Nucleus; Corticosterone; Disease Models | 2021 |
High and low anxiety phenotypes in a rat model of complex post-traumatic stress disorder are associated with different alterations in regional brain monoamine neurotransmission.
Topics: Animals; Anxiety; Behavior, Animal; Brain; Corticosterone; Disease Models, Animal; Disease Susceptib | 2020 |
Effects of early life social experience on fear extinction and related glucocorticoid profiles - behavioral and neurochemical approaches in a rat model of PTSD.
Topics: Animals; Brain; Conditioning, Classical; Corticosterone; Disease Models, Animal; Extinction, Psychol | 2020 |
Social isolation in mice: behavior, immunity, and tumor growth.
Topics: Animals; Behavior, Animal; Corticosterone; Male; Mice; Mice, Inbred C3H; Pituitary-Adrenal System; S | 2021 |
Beneficial role of central anticholinergic agent in preventing the development of symptoms in mouse model of post-traumatic stress disorder.
Topics: Animals; Behavior, Animal; Corticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; | 2020 |
Hexobarbital Sleep Test for Predicting the Susceptibility or Resistance to Experimental Posttraumatic Stress Disorder.
Topics: Animals; Corticosterone; Disease Susceptibility; Hexobarbital; Hypnotics and Sedatives; Male; Rats; | 2020 |
Acute exposure of rats to a severe stressor alters the circadian pattern of corticosterone and sensitizes to a novel stressor: Relationship to pre-stress individual differences in resting corticosterone levels.
Topics: Adrenocorticotropic Hormone; Animals; Circadian Rhythm; Conditioning, Classical; Corticosterone; Hyp | 2020 |
Non-selective orexin-receptor antagonist attenuates stress-re-stress-induced core PTSD-like symptoms in rats: Behavioural and neurochemical analyses.
Topics: Amygdala; Animals; Azepines; Corticosterone; Disease Models, Animal; Male; Orexin Receptor Antagonis | 2021 |
Maternal Separation-Induced Histone Acetylation Correlates with BDNF-Programmed Synaptic Changes in an Animal Model of PTSD with Sex Differences.
Topics: Acetylation; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; CA1 Region, Hippocampal; | 2021 |
Anxiety-like behavior and neuroendocrine changes in offspring resulting from gestational post-traumatic stress disorder.
Topics: Animals; Anxiety; Behavior, Animal; Corticosterone; Female; Male; Maternal Behavior; Pregnancy; Pren | 2021 |
Environmental enrichment modulates HPA axis reprogramming in adult male rats exposed to early adolescent stress.
Topics: Animals; Corticosterone; Corticotropin-Releasing Hormone; Hypothalamo-Hypophyseal System; Hypothalam | 2021 |
Is PTSD-Phenotype Associated with HPA-Axis Sensitivity?: The Endocannabinoid System in Modulating Stress Response in Rats.
Topics: Animals; Behavior, Animal; Corticosterone; Endocannabinoids; Hypothalamo-Hypophyseal System; Male; P | 2021 |
Is PTSD-Phenotype Associated with HPA-Axis Sensitivity? Feedback Inhibition and Other Modulating Factors of Glucocorticoid Signaling Dynamics.
Topics: Animals; Arginine Vasopressin; Behavior, Animal; Brain; Corticosterone; Disease Models, Animal; Huma | 2021 |
Supplementation of taurine improves ionic homeostasis and mitochondrial function in the rats exhibiting post-traumatic stress disorder-like symptoms.
Topics: Animals; Corticosterone; Maze Learning; Paroxetine; Rats; Stress Disorders, Post-Traumatic; Taurine | 2021 |
Predator odor evokes sex-independent stress responses in male and female Wistar rats and reduces phosphorylation of cyclic-adenosine monophosphate response element binding protein in the male, but not the female hippocampus.
Topics: Animals; Blood Glucose; Corticosterone; CREB-Binding Protein; Cyclic AMP; Disease Models, Animal; Fe | 2017 |
Posttraumatic Stress Disorder Disturbs Coronary Tone and Its Regulatory Mechanisms.
Topics: Animals; Blood Pressure; Coronary Vessels; Corticosterone; Isolated Heart Preparation; Male; Maze Le | 2018 |
Susceptibility and Resilience to Posttraumatic Stress Disorder-like Behaviors in Inbred Mice.
Topics: Animals; Basolateral Nuclear Complex; Behavior, Animal; Corticosterone; Disease Models, Animal; Dise | 2017 |
Persistent effects of acute stress on fear and drug-seeking in a novel model of the comorbidity between post-traumatic stress disorder and addiction.
Topics: Animals; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Conditioning, Operan | 2017 |
Blunted basal corticosterone pulsatility predicts post-exposure susceptibility to PTSD phenotype in rats.
Topics: Acoustic Stimulation; Animals; Biomarkers; Corticosterone; Disease Models, Animal; Disease Susceptib | 2018 |
Neuropeptide S in the basolateral amygdala mediates an adaptive behavioral stress response in a rat model of posttraumatic stress disorder by increasing the expression of BDNF and the neuropeptide YY1 receptor.
Topics: Adaptation, Psychological; Animals; Basolateral Nuclear Complex; Brain-Derived Neurotrophic Factor; | 2018 |
Influence of early stress on memory reconsolidation: Implications for post-traumatic stress disorder treatment.
Topics: Adrenergic beta-Antagonists; Animals; Conditioning, Classical; Corticosterone; Disease Models, Anima | 2018 |
Anxiolytic-like effects of paeoniflorin in an animal model of post traumatic stress disorder.
Topics: Adrenocorticotropic Hormone; Animals; Anti-Anxiety Agents; Behavior, Animal; Corticosterone; Cortico | 2018 |
Consequences of a double hit of stress during the perinatal period and midlife in female rats: Mismatch or cumulative effect?
Topics: Adaptation, Psychological; Age Factors; Animals; Behavior, Animal; Corticosterone; Endocrine System; | 2018 |
Early life stress in rats sex-dependently affects remote endocrine rather than behavioral consequences of adult exposure to contextual fear conditioning.
Topics: Aging; Animals; Behavior, Animal; Conditioning, Classical; Corticosterone; Endocrine System; Fear; F | 2018 |
Intermittent hypoxia improves behavioral and adrenal gland dysfunction induced by posttraumatic stress disorder in rats.
Topics: Adrenal Cortex; Adrenal Gland Diseases; Adrenal Glands; Altitude; Animals; Anxiety; Corticosterone; | 2018 |
Hyperbaric oxygen therapy restored traumatic stress-induced dysregulation of fear memory and related neurochemical abnormalities.
Topics: Animals; Biogenic Monoamines; Conditioning, Psychological; Corticosterone; Disease Models, Animal; E | 2019 |
Effects of Oxytocin on Fear Memory and Neuroinflammation in a Rodent Model of Posttraumatic Stress Disorder.
Topics: Animals; Brain; Corticosterone; Cytokines; Disease Models, Animal; Extinction, Psychological; Fear; | 2018 |
Post-Stress Fructose and Glucose Ingestion Exhibit Dissociable Behavioral and Physiological Effects.
Topics: Animals; Behavior, Animal; Blood Glucose; Corticosterone; Disease Models, Animal; Eating; Fructose; | 2019 |
New neurons restore structural and behavioral abnormalities in a rat model of PTSD.
Topics: Animals; Anxiety; Behavior, Animal; CA1 Region, Hippocampal; Cell Proliferation; Corticosterone; Den | 2019 |
Affective profiling for anxiety-like behavior in a rodent model of mTBI.
Topics: Amygdala; Animals; Anxiety; Blast Injuries; Brain Concussion; Brain Injuries; Comorbidity; Corticost | 2019 |
The anxiolytic-like effects of ginsenoside Rg2 on an animal model of PTSD.
Topics: Adrenocorticotropic Hormone; Animals; Anti-Anxiety Agents; Antidepressive Agents; Corticosterone; Co | 2019 |
Individual variability in behavior and functional networks predicts vulnerability using an animal model of PTSD.
Topics: Animals; Anxiety; Avoidance Learning; Behavior, Animal; Brain; Corticosterone; Disease Models, Anima | 2019 |
Methyl-CpG binding protein 2 functional alterations provide vulnerability to develop behavioral and molecular features of post-traumatic stress disorder in male mice.
Topics: Animals; Avoidance Learning; Conditioning, Psychological; Corticosterone; Epigenomics; Fluoxetine; G | 2019 |
Risperidone ameliorates post-traumatic stress disorder-like symptoms in modified stress re-stress model.
Topics: Animals; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Brain; Corticosterone; Dise | 2013 |
A ghrelin-growth hormone axis drives stress-induced vulnerability to enhanced fear.
Topics: Amygdala; Animals; Chronic Disease; Corticosterone; Corticotropin-Releasing Hormone; Disease Models, | 2014 |
Amnesia for early life stress does not preclude the adult development of posttraumatic stress disorder symptoms in rats.
Topics: Aging; Amnesia; Animals; Avoidance Learning; Brain; Conditioning, Psychological; Corticosterone; Ele | 2014 |
Immediate ketamine treatment does not prevent posttraumatic stress responses in an animal model for PTSD.
Topics: Acoustic Stimulation; Animals; Anti-Anxiety Agents; Corticosterone; Dexamethasone; Disease Models, A | 2014 |
Adolescent traumatic stress experience results in less robust conditioned fear and post-extinction fear cue responses in adult rats.
Topics: Animals; Conditioning, Operant; Corticosterone; Cues; Extinction, Psychological; Fear; Male; Rats; R | 2014 |
Long-term effects of traumatic stress on subsequent contextual fear conditioning in rats.
Topics: Animals; Conditioning, Psychological; Corticosterone; Electroshock; Fear; Male; Metyrapone; Random A | 2014 |
Moderate treadmill exercise rescues anxiety and depression-like behavior as well as memory impairment in a rat model of posttraumatic stress disorder.
Topics: Anhedonia; Animals; Anxiety Disorders; Corticosterone; Depressive Disorder; Disease Models, Animal; | 2014 |
Witnessing traumatic events causes severe behavioral impairments in rats.
Topics: Animals; Anxiety; Corticosterone; Depression; Disease Models, Animal; Dominance-Subordination; Housi | 2014 |
Development of behavioral and hormonal disorders in prenatally stressed female rats on the model of posttraumatic stress disorder.
Topics: Animals; Anxiety; Corticosterone; Depression; Female; Pregnancy; Prenatal Exposure Delayed Effects; | 2014 |
Expression profiling associates blood and brain glucocorticoid receptor signaling with trauma-related individual differences in both sexes.
Topics: Amygdala; Animals; Behavior, Animal; Brain; Corticosterone; Female; Gene Expression Profiling; Gene | 2014 |
Corticosterone mitigates the stress response in an animal model of PTSD.
Topics: Acoustic Stimulation; Animals; Anti-Inflammatory Agents; Corticosterone; Disease Models, Animal; Dos | 2015 |
Grape powder prevents cognitive, behavioral, and biochemical impairments in a rat model of posttraumatic stress disorder.
Topics: Animals; Anxiety; Brain-Derived Neurotrophic Factor; Cognition; Corticosterone; Disease Models, Anim | 2015 |
Towards a better preclinical model of PTSD: characterizing animals with weak extinction, maladaptive stress responses and low plasma corticosterone.
Topics: Animals; Behavior, Animal; Conditioning, Classical; Corticosterone; Disease Models, Animal; Extincti | 2015 |
A rodent model of traumatic stress induces lasting sleep and quantitative electroencephalographic disturbances.
Topics: Analysis of Variance; Animals; Brain Waves; Corticosterone; Disease Models, Animal; Electroencephalo | 2015 |
Norepinephrine and corticosterone in the medial prefrontal cortex and hippocampus predict PTSD-like symptoms in mice.
Topics: Animals; Arousal; Corticosterone; Extracellular Space; Fear; Hippocampus; Male; Mice; Mice, Inbred C | 2015 |
Risperidone Attenuates Modified Stress-Re-stress Paradigm-Induced Mitochondrial Dysfunction and Apoptosis in Rats Exhibiting Post-traumatic Stress Disorder-Like Symptoms.
Topics: Animals; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Apoptosis; Brain; Corticost | 2015 |
Beyond the HPA-axis: The role of the gonadal steroid hormone receptors in modulating stress-related responses in an animal model of PTSD.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Brain; Chi-Square Distribution; Corticosterone; | 2015 |
Inhibiting corticosterone synthesis during fear memory formation exacerbates cued fear extinction memory deficits within the single prolonged stress model.
Topics: Animals; Conditioning, Psychological; Corticosterone; Cues; Disease Models, Animal; Enzyme Inhibitor | 2015 |
ApoE2 Exaggerates PTSD-Related Behavioral, Cognitive, and Neuroendocrine Alterations.
Topics: Activities of Daily Living; Animals; Apolipoprotein E2; Chronobiology Disorders; Cognition; Corticos | 2015 |
Long-term effects of early adolescent stress: dysregulation of hypothalamic-pituitary-adrenal axis and central corticotropin releasing factor receptor 1 expression in adult male rats.
Topics: Animals; Anxiety; Corticosterone; Depression; Disease Models, Animal; Electroshock; Exercise Therapy | 2015 |
[The hypothalamic-pituitary-adrenal axis activity in prenatal stressed female rats in the model of posttraumatic stress disorder].
Topics: Animals; Corticosterone; Corticotropin-Releasing Hormone; Disease Models, Animal; Female; Glucocorti | 2014 |
Preventive effects of ginsenoside Rg1 on post-traumatic stress disorder (PTSD)-like behavior in male C57/B6 mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Corticotropin-Releasing Hormone; D | 2015 |
Post-traumatic stress avoidance is attenuated by corticosterone and associated with brain levels of steroid receptor co-activator-1 in rats.
Topics: Amygdala; Animals; Avoidance Learning; Behavior, Animal; Brain; Corticosterone; Hippocampus; Hypotha | 2016 |
Vicarious social defeat stress: Bridging the gap between physical and emotional stress.
Topics: Animals; Behavior, Animal; Corticosterone; Disease Models, Animal; Fear; Male; Mice; Social Behavior | 2016 |
From Memory Impairment to Posttraumatic Stress Disorder-Like Phenotypes: The Critical Role of an Unpredictable Second Traumatic Experience.
Topics: AIDS-Related Complex; Animals; Avoidance Learning; Brain-Derived Neurotrophic Factor; Corticosterone | 2015 |
Investigating the role of nisoldipine in foot-shock-induced post-traumatic stress disorder in mice.
Topics: Animals; Anxiety; Behavior, Animal; Corticosterone; Disease Models, Animal; Electroshock; Mice; Moto | 2016 |
Severe, multimodal stress exposure induces PTSD-like characteristics in a mouse model of single prolonged stress.
Topics: Animals; Behavior, Animal; Conditioning, Classical; Corticosterone; Cues; Disease Models, Animal; Ex | 2016 |
Effects of In utero environment and maternal behavior on neuroendocrine and behavioral alterations in a mouse model of prenatal trauma.
Topics: Animals; Anxiety; Behavior, Animal; Conditioning, Classical; Corticosterone; Disease Models, Animal; | 2016 |
Activity of the Hypothalamic-Pituitary-Adrenal System in Prenatally Stressed Male Rats on the Experimental Model of Post-Traumatic Stress Disorder.
Topics: Animals; Corticosterone; Corticotropin-Releasing Hormone; Disease Models, Animal; Female; Hypothalam | 2016 |
Anxiolytic effects of GLYX-13 in animal models of posttraumatic stress disorder-like behavior.
Topics: Adrenocorticotropic Hormone; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Corticosterone | 2016 |
Traumatic stress causes distinctive effects on fear circuit catecholamines and the fear extinction profile in a rodent model of posttraumatic stress disorder.
Topics: Animals; Blood Pressure; Brain; Conditioning, Classical; Corticosterone; Disease Models, Animal; Dop | 2016 |
Behavioral Activity and Some Markers of Posttraumatic Stress Disorder among Serotoninergic System Indicators and Glucocorticoid Metabolizing Enzymes in Rats with Different Duration of Hexenal Sleep.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Animals; Anxiety; Behavior, Animal; Corticosterone; Glucocort | 2016 |
Epigenetic mechanism of maternal post-traumatic stress disorder in delayed rat offspring development: dysregulation of methylation and gene expression.
Topics: Animals; Body Weight; Corticosterone; Developmental Disabilities; DNA Methylation; Epigenesis, Genet | 2016 |
The wake-promoting drug modafinil stimulates specific hypothalamic circuits to promote adaptive stress responses in an animal model of PTSD.
Topics: Adaptation, Psychological; Animals; Arousal; Benzhydryl Compounds; Corticosterone; Disease Models, A | 2016 |
Reducing post-traumatic anxiety by immunization.
Topics: Adaptation, Psychological; Animals; Anti-Inflammatory Agents; Anxiety; Behavior, Animal; Brain; Brai | 2008 |
Acute episodes of predator exposure in conjunction with chronic social instability as an animal model of post-traumatic stress disorder.
Topics: Animals; Corticosterone; Disease Models, Animal; Male; Maze Learning; Predatory Behavior; Rats; Rats | 2008 |
Early post-stressor intervention with high-dose corticosterone attenuates posttraumatic stress response in an animal model of posttraumatic stress disorder.
Topics: Acoustic Stimulation; Animals; Cats; Corticosterone; Disease Models, Animal; Dose-Response Relations | 2008 |
A single exposure to immobilization causes long-lasting pituitary-adrenal and behavioral sensitization to mild stressors.
Topics: Adaptation, Physiological; Adrenocorticotropic Hormone; Animals; Behavior, Animal; Corticosterone; F | 2008 |
The possible use of hypoxic preconditioning for the prophylaxis of post-stress depressive episodes.
Topics: Analysis of Variance; Animals; Atmospheric Pressure; Corticosterone; Depressive Disorder; Disease Mo | 2008 |
The role of the galaninergic system in modulating stress-related responses in an animal model of posttraumatic stress disorder.
Topics: Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corticosterone; Coumarins; Disease Mod | 2009 |
Prenatal stress exacerbates the impact of an aversive procedure on the corticosterone response to stress in female rats.
Topics: Adaptation, Psychological; Animals; Corticosterone; Female; Pregnancy; Prenatal Exposure Delayed Eff | 2009 |
Alprazolam treatment immediately after stress exposure interferes with the normal HPA-stress response and increases vulnerability to subsequent stress in an animal model of PTSD.
Topics: Acoustic Stimulation; Alprazolam; Analysis of Variance; Animals; Anti-Anxiety Agents; Behavior, Anim | 2009 |
Pre-pubertal stress exposure affects adult behavioral response in association with changes in circulating corticosterone and brain-derived neurotrophic factor.
Topics: Age Factors; Algorithms; Animals; Behavior, Animal; Brain; Brain-Derived Neurotrophic Factor; Cortic | 2009 |
A distinct pattern of intracellular glucocorticoid-related responses is associated with extreme behavioral response to stress in an animal model of post-traumatic stress disorder.
Topics: Analysis of Variance; Animals; Brain; Cats; Corticosterone; Disease Models, Animal; Early Growth Res | 2009 |
DNA methylation in vulnerability to post-traumatic stress in rats: evidence for the role of the post-synaptic density protein Dlgap2.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Behavior, Animal; Computational Biology; Cortic | 2010 |
Hippocampal microinfusion of oxytocin attenuates the behavioural response to stress by means of dynamic interplay with the glucocorticoid-catecholamine responses.
Topics: Animals; Behavior, Animal; Catecholamines; Corticosterone; Glucocorticoids; Hippocampus; Male; Micro | 2010 |
Enhanced fear recall and emotional arousal in rats recovering from chronic variable stress.
Topics: Analysis of Variance; Animals; Arousal; Chronic Disease; Cohort Studies; Conditioning, Psychological | 2010 |
7,8-dihydroxyflavone, a TrkB receptor agonist, blocks long-term spatial memory impairment caused by immobilization stress in rats.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Flavanones; Hypothalamo-Hypophyseal System; Ma | 2012 |
Enduring sensorimotor gating abnormalities following predator exposure or corticotropin-releasing factor in rats: a model for PTSD-like information-processing deficits?
Topics: Acoustic Stimulation; Animals; Corticosterone; Corticotropin-Releasing Hormone; Ferrets; Male; Preda | 2012 |
The characteristic long-term upregulation of hippocampal NF-κB complex in PTSD-like behavioral stress response is normalized by high-dose corticosterone and pyrrolidine dithiocarbamate administered immediately after exposure.
Topics: Animals; Cats; Corticosterone; Drug Administration Schedule; Male; NF-kappa B; Pyrrolidines; Rats; R | 2011 |
Glucocorticoids can induce PTSD-like memory impairments in mice.
Topics: Amygdala; Animals; Conditioning, Psychological; Corticosterone; Cues; Electroshock; Fear; Hippocampu | 2012 |
[Prenatal stressed female rats develop stable anxious and depressive state in experimental model of post-traumatic stress disorder].
Topics: Animals; Anxiety; Corticosterone; Depression; Disease Models, Animal; Female; Humans; Hydrocortisone | 2011 |
Glucocorticoids protect against the delayed behavioral and cellular effects of acute stress on the amygdala.
Topics: Adrenalectomy; Amygdala; Analysis of Variance; Animals; Anxiety; Corticosterone; Dendritic Spines; D | 2012 |
Susceptibility to PTSD-like behavior is mediated by corticotropin-releasing factor receptor type 2 levels in the bed nucleus of the stria terminalis.
Topics: Animals; Behavior, Animal; Corticosterone; Disease Models, Animal; Gene Knockdown Techniques; Histon | 2012 |
Post-exposure sleep deprivation facilitates correctly timed interactions between glucocorticoid and adrenergic systems, which attenuate traumatic stress responses.
Topics: Acoustic Stimulation; Adrenergic Agonists; Analysis of Variance; Animals; Corticosterone; Dendrites; | 2012 |
Sex comparison on long-lasting behavioral and physiological disturbances induced by single shock experience in rats.
Topics: Animals; Avoidance Learning; Body Temperature; Corticosterone; Cues; Disease Models, Animal; Electro | 2012 |
Single intranasal neuropeptide Y infusion attenuates development of PTSD-like symptoms to traumatic stress in rats.
Topics: Administration, Intranasal; Adrenocorticotropic Hormone; Animals; Blotting, Western; Corticosterone; | 2013 |
Increased neuronal apoptosis in medial prefrontal cortex is accompanied with changes of Bcl-2 and Bax in a rat model of post-traumatic stress disorder.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Corticosterone; Male; Neurons; Prefrontal Cortex; Pr | 2013 |
The relevance of differential response to trauma in an animal model of posttraumatic stress disorder.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Discrimination Learning; Disease Models, Anima | 2003 |
Endocrine, cognitive and hippocampal/cortical 5HT 1A/2A receptor changes evoked by a time-dependent sensitisation (TDS) stress model in rats.
Topics: Animals; Anxiety; Arousal; Cerebral Cortex; Cognition; Corticosterone; Cues; Endocrine Glands; Hippo | 2003 |
Stress-restress evokes sustained iNOS activity and altered GABA levels and NMDA receptors in rat hippocampus.
Topics: Animals; Chromatography, High Pressure Liquid; Corticosterone; Electrochemistry; Enzyme Inhibitors; | 2004 |
The effects of repeated intra-amygdala CRF injections on rat behavior and HPA axis function after stress.
Topics: Adrenocorticotropic Hormone; Amygdala; Animals; Behavior, Animal; Corticosterone; Corticotropin-Rele | 2004 |
Long-term behavioural alterations in female rats after a single intense footshock followed by situational reminders.
Topics: Animals; Anxiety; Behavior, Animal; Circadian Rhythm; Corticosterone; Disease Models, Animal; Electr | 2005 |
Decreased circulatory levels of neuroactive steroids in behaviourally more extremely affected rats subsequent to exposure to a potentially traumatic experience.
Topics: Acoustic Stimulation; Animals; Anxiety; Behavior, Animal; Circadian Rhythm; Corticosterone; Dehydroe | 2007 |
Long-term down-regulation of BDNF mRNA in rat hippocampal CA1 subregion correlates with PTSD-like behavioural stress response.
Topics: Acoustic Stimulation; Animals; Anxiety; Behavior, Animal; Blotting, Western; Brain Chemistry; Brain- | 2007 |
Long lasting sex-specific effects upon behavior and S100b levels after maternal separation and exposure to a model of post-traumatic stress disorder in rats.
Topics: Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Conditioning, Psychological; Cort | 2007 |
The immediate early gene Arc is associated with behavioral resilience to stress exposure in an animal model of posttraumatic stress disorder.
Topics: Adaptation, Physiological; Analysis of Variance; Animals; Behavior, Animal; Cats; Corticosterone; Cy | 2008 |
Glucocorticoid receptor activation is involved in producing abnormal phenotypes of single-prolonged stress rats: a putative post-traumatic stress disorder model.
Topics: Amygdala; Animals; Anxiety Disorders; Avoidance Learning; Cell Death; Corticosterone; Disease Models | 2007 |
Post-traumatic stress behavioural responses in inbred mouse strains: can genetic predisposition explain phenotypic vulnerability?
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Cluster Analysis; Co | 2008 |
Gender-related qualitative differences in baseline and post-stress anxiety responses are not reflected in the incidence of criterion-based PTSD-like behaviour patterns.
Topics: Animals; Anxiety Disorders; Behavior, Animal; Corticosterone; Depressive Disorder, Major; Disease Mo | 2009 |
Acoustic startle amplitude predicts vulnerability to develop post-traumatic stress hyper-responsivity and associated plasma corticosterone changes in rats.
Topics: Acoustic Stimulation; Animals; Corticosterone; Data Interpretation, Statistical; Electroshock; Male; | 2008 |
Delayed startle sensitization distinguishes rats exposed to one or three stress sessions: further evidence toward an animal model of PTSD.
Topics: Animals; Arousal; Corticosterone; Disease Models, Animal; Electroshock; Male; Rats; Rats, Sprague-Da | 1995 |
Stress-restress: effects on ACTH and fast feedback.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Feedback; Hydrocortisone; Hypothalamo-Hypophys | 1997 |
[Effects of ohmefentanyl at anesthetic dose on plasma levels of corticosterone, cortisol and antidiuretic hormone in rats].
Topics: Analgesics; Animals; Corticosterone; Fentanyl; Male; Rats; Stress Disorders, Post-Traumatic; Vasopre | 1997 |
Genetic predisposition and the development of posttraumatic stress disorder in an animal model.
Topics: Animals; Brain; Cognition Disorders; Corticosterone; Disease Models, Animal; Genetic Predisposition | 2001 |