Page last updated: 2024-08-17

cordycepin and Disease Models, Animal

cordycepin has been researched along with Disease Models, Animal in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.13)18.2507
2000's2 (6.25)29.6817
2010's17 (53.13)24.3611
2020's12 (37.50)2.80

Authors

AuthorsStudies
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Hui, K; Shao, Q; Yan, Q; Zhang, H1
Cheng, J; Li, M; Li, S; Su, Y; Wen, J; Zhang, Y1
Han, YY; Huang, SY; Li, CH; Liu, L; Mai, ZF; Shang, YJ; Su, ZY; Zeng, ZW1
Luo, S; Luo, Y; Mo, J; Pang, H; Ren, Z; Wang, K; Wang, X; Wei, J; Xi, D; Yang, R1
Gu, Y; Li, Z; Lin, Z; Ma, H; Zhang, S1
Shi, J; Yang, J; Zhou, Y1
Gao, L; Gu, HY; Lian, DB; Liu, PF; Tao, WW; Tao, XM; Yan, D; Zhao, B1
Cao, D; Jiang, D; Li, J; Yu, H; Zhou, D1
Gong, X; Li, T; Sha, L; Wan, R1
Gao, Y; Gong, Y; Huang, Y; Jin, P; Li, C; Luo, C; Misilimu, D; Wang, K; Wei, P; Wen, H1
Charoenlappanit, S; Fungfuang, W; Parunyakul, K; Phaonakrop, N; Roytrakul, S; Srisuksai, K1
Cai, Y; Cheng, Y; Shang, H; Song, Y; Wei, Y; Wu, Z; Yang, W; Zhao, W1
Arslan, MS; Arslan, S; Aydogdu, B; Basuguy, E; Ibiloglu, I; Kaplan, I; Okur, MH; Zeytun, H1
Hsu, WH; Lai, YJ; Lin, LT; Tai, CJ; Wu, SC1
Han, NR; Jeong, HJ; Kim, HM; Moon, PD1
Alves-Cruzeiro, J; Brito, F; Carmo-Silva, S; de Almeida, LP; Koppenol, R; Marcelo, A; Matos, CA; Mendonça, L; Nóbrega, C; Vasconcelos-Ferreira, A1
Fen, N; Guanghui, L; Jiali, F; Junjie, M; Lei, Z; Lu, X; Tiantian, W; Xingqiang, L; Yuhe, G; Zheng, C; Zhongpeng, Y1
Ashraf, S; Burston, JJ; Chapman, V; de Moor, CH; Gandhi, RD; Gowler, P; Piccinini, AM; Radhi, M; Thorn, GJ; Walsh, DA1
Bao, H; Chen, X; Du, J; Feng, L; Hou, Y; Jia, Y; Li, H; Luo, S; Wang, C; Wang, G; Xiao, C; Xiao, L; Xiao, Y; Yu, H; Zhang, D; Zhang, Y; Zhou, J; Zhu, K1
Cao, T; Liu, Y; Qi, D; Wan, Q; Xu, R; Xu, Y1
Bogen, O; Chu, C; Ferrari, LF; Levine, JD1
Jang, YC; Kang, DH; Kang, JC; Kim, SK; Park, ES; Park, JS; Shin, HS; Yang, MK1
Bao, RF; Cao, Y; Hu, YP; Jiang, L; Li, HF; Li, ML; Liu, YB; Lu, W; Mu, JS; Shu, YJ; Tan, ZJ; Wang, P; Wang, XA; Weng, H; Wu, WG; Wu, XS; Xiang, SS; Ye, YY; Zhang, F1
Juan, D; Shihai, Y; Tianzhu, Z1
Bao, H; Du, J; Du, K; Hou, Y; Li, B; Li, M; Nie, J; Shan, L; Xiao, C; Xu, X; Yang, H; Yao, Y; Zhang, GY; Zheng, B; Zhu, M1
He, Y; Liu, Y; Si, Z; Wang, A; Wang, D; Wang, K; Xu, S; Yuan, J; Zhang, S1
Jan, YJ; Ko, BS; Liang, SM; Liou, JY; Lu, YJ; Shyue, SK; Yet, SF1
Cha, MJ; Chang, W; Hwang, KC; Kim, HJ; Kim, TW; Lim, S; Song, BW; Song, H; Sung, JM1
Qu, K; Sun, Y; Wang, YH; Zhu, HB1
Ferella, M; Goto, H; Kristensson, K; Masocha, W; McCaffrey, R; Petitto-Assis, F; Rottenberg, ME; Wigzell, H1
McCaffrey, RP; Sugar, AM1

Other Studies

32 other study(ies) available for cordycepin and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
Cordycepin Ameliorates Intracerebral Hemorrhage Induced Neurological and Cognitive Impairments Through Reducing Anti-Oxidative Stress in a Mouse Model.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2022, Volume: 31, Issue:1

    Topics: Animals; Antioxidants; Cerebral Hemorrhage; Cognitive Dysfunction; Deoxyadenosines; Disease Models, Animal; Humans; Mice; Oxidative Stress; Quality of Life

2022
Cordycepin induces M1/M2 macrophage polarization to attenuate the liver and lung damage and immunodeficiency in immature mice with sepsis via NF-κB/p65 inhibition.
    The Journal of pharmacy and pharmacology, 2022, Feb-01, Volume: 74, Issue:2

    Topics: Animals; Deoxyadenosines; Disease Models, Animal; Liver Diseases; Lung Diseases; Macrophages; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Sepsis; Signal Transduction; Transcription Factor RelA

2022
Cordycepin improved the cognitive function through regulating adenosine A
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2023, Volume: 110

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adenosine; Animals; Cognition; Disease Models, Animal; Mice; Mice, Inbred C57BL; Parkinson Disease

2023
Cordycepin Attenuates IFN-γ-Induced Macrophage IP-10 and Mig Expressions by Inhibiting STAT1 Activity in CFA-Induced Inflammation Mice Model.
    Inflammation, 2020, Volume: 43, Issue:2

    Topics: Animals; Antineoplastic Agents; Chemokine CXCL10; Chemokine CXCL9; Deoxyadenosines; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Freund's Adjuvant; Gene Expression; Inflammation; Interferon-gamma; Macrophages; Mice; Random Allocation; RAW 264.7 Cells; STAT1 Transcription Factor

2020
Cordycepin promotes osteogenesis of bone marrow-derived mesenchymal stem cells and accelerates fracture healing via hypoxia in a rat model of closed femur fracture.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 125

    Topics: Animals; Bone Regeneration; Cells, Cultured; Chondrogenesis; Deoxyadenosines; Disease Models, Animal; Femur; Fracture Healing; Fractures, Closed; Hypoxia; Male; Mesenchymal Stem Cells; Osteogenesis; Rats

2020
Cordycepin protects against acute pancreatitis by modulating NF-κB and NLRP3 inflammasome activation via AMPK.
    Life sciences, 2020, Jun-15, Volume: 251

    Topics: Acute Disease; AMP-Activated Protein Kinases; Animals; Biomarkers; Cytokines; Deoxyadenosines; Disease Models, Animal; Inflammasomes; Inflammation; Inflammation Mediators; Male; Mice; Mice, Inbred ICR; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Pancreatitis; Protective Agents

2020
Cordycepin Alleviates Anterior Cruciate Ligament Transection (ACLT)-Induced Knee Osteoarthritis Through Regulating TGF-β Activity and Autophagy.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Animals; Anterior Cruciate Ligament; Autophagy; Deoxyadenosines; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Injections, Intravenous; Male; Medicine, Chinese Traditional; Osteoarthritis, Knee; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta

2020
A Comparative Study on 5hmC Targeting Regulation of Neurons in AD Mice by Several Natural Compounds.
    BioMed research international, 2020, Volume: 2020

    Topics: 5-Methylcytosine; Alzheimer Disease; Animals; Cell Line, Tumor; Deoxyadenosines; Disease Models, Animal; Humans; Mice; Mice, Mutant Strains; Neurons; Resveratrol

2020
Cordycepin attenuates high-fat diet-induced non-alcoholic fatty liver disease via down-regulation of lipid metabolism and inflammatory responses.
    International immunopharmacology, 2021, Volume: 91

    Topics: Animals; Anti-Inflammatory Agents; Deoxyadenosines; Diet, High-Fat; Disease Models, Animal; Down-Regulation; Hyperlipidemias; Hypolipidemic Agents; Inflammation Mediators; Lipids; Lipogenesis; Liver; Male; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity; Oxidation-Reduction

2021
Cordycepin confers long-term neuroprotection via inhibiting neutrophil infiltration and neuroinflammation after traumatic brain injury.
    Journal of neuroinflammation, 2021, Jun-15, Volume: 18, Issue:1

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Injuries, Traumatic; Deoxyadenosines; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Microglia; Neuroinflammatory Diseases; Neuroprotection; Neuroprotective Agents; Neutrophil Infiltration

2021
Metabolic impacts of cordycepin on hepatic proteomic expression in streptozotocin-induced type 1 diabetic mice.
    PloS one, 2021, Volume: 16, Issue:8

    Topics: Animals; Antifungal Agents; Blood Glucose; Deoxyadenosines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Insulin; Liver; Male; Mice; Mice, Inbred C57BL; Proteome; Signal Transduction

2021
Cordycepin confers neuroprotection in mice models of intracerebral hemorrhage via suppressing NLRP3 inflammasome activation.
    Metabolic brain disease, 2017, Volume: 32, Issue:4

    Topics: Animals; Brain Edema; Cell Death; Cerebral Hemorrhage; Deoxyadenosines; Disease Models, Animal; Inflammasomes; Male; Mice; Mice, Inbred ICR; Neurons; Neuroprotective Agents; NLR Family, Pyrin Domain-Containing 3 Protein

2017
Protective Effect of Cordycepin on Experimental Testicular Ischemia/Reperfusion Injury in Rats.
    Journal of investigative surgery : the official journal of the Academy of Surgical Research, 2018, Volume: 31, Issue:1

    Topics: Animals; Antioxidants; Deoxyadenosines; Disease Models, Animal; Humans; Interleukin-1beta; Interleukin-6; Male; Malondialdehyde; Oxidative Stress; Protective Agents; Rats; Rats, Wistar; Reperfusion Injury; Sperm Count; Spermatozoa; Testis; Tumor Necrosis Factor-alpha

2018
Optimal conditions for cordycepin production in surface liquid-cultured Cordyceps militaris treated with porcine liver extracts for suppression of oral cancer.
    Journal of food and drug analysis, 2018, Volume: 26, Issue:1

    Topics: Animals; Antineoplastic Agents; Biological Products; Cell Cycle; Cell Line, Tumor; Cell Survival; Cordyceps; Cricetinae; Deoxyadenosines; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Liver Extracts; Male; Mitochondria; Mouth Neoplasms; Swine; Xenograft Model Antitumor Assays

2018
Cordycepin ameliorates skin inflammation in a DNFB-challenged murine model of atopic dermatitis.
    Immunopharmacology and immunotoxicology, 2018, Volume: 40, Issue:5

    Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents; Deoxyadenosines; Dermatitis, Atopic; Dinitrochlorobenzene; Dinitrofluorobenzene; Disease Models, Animal; Female; Histamine; Immunoglobulin E; Mice; Mice, Inbred C57BL; Skin

2018
Cordycepin activates autophagy through AMPK phosphorylation to reduce abnormalities in Machado-Joseph disease models.
    Human molecular genetics, 2019, 01-01, Volume: 28, Issue:1

    Topics: Adenylate Kinase; Animals; Ataxin-3; Autophagy; Deoxyadenosines; Disease Models, Animal; Machado-Joseph Disease; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Tissue Proteins; Nuclear Proteins; Phosphorylation; Repressor Proteins; Trinucleotide Repeats

2019
Ethylene carbodiimide-fixed donor splenocytes combined with cordycepin induce long-term protection to mice cardiac allografts.
    Transplant immunology, 2019, Volume: 56

    Topics: Animals; Anti-Inflammatory Agents; Carbodiimides; Cells, Cultured; Combined Modality Therapy; Cytokines; Deoxyadenosines; Disease Models, Animal; Ethylenes; Graft Rejection; Graft Survival; Heart Transplantation; Humans; Immune Tolerance; Immunotherapy, Adoptive; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Spleen; Tissue Donors; Transplantation, Homologous

2019
The polyadenylation inhibitor cordycepin reduces pain, inflammation and joint pathology in rodent models of osteoarthritis.
    Scientific reports, 2019, 03-18, Volume: 9, Issue:1

    Topics: Animals; Arthritis, Experimental; Deoxyadenosines; Disease Models, Animal; Humans; Inflammation; Joints; Mice; NF-kappa B; Osteoarthritis; Pain; Polyadenylation; Rats; Signal Transduction

2019
Cordycepin (3'-deoxyadenosine) promotes remyelination via suppression of neuroinflammation in a cuprizone-induced mouse model of demyelination.
    International immunopharmacology, 2019, Volume: 75

    Topics: Animals; Anti-Inflammatory Agents; Astrocytes; Corpus Callosum; Cuprizone; Cytokines; Demyelinating Diseases; Deoxyadenosines; Disease Models, Animal; Hippocampus; Male; Mice; Mice, Inbred C57BL; Neuroglia; Neuroprotective Agents; Remyelination

2019
The protective effect of Cordycepin on diabetic nephropathy through autophagy induction in vivo and in vitro.
    International urology and nephrology, 2019, Volume: 51, Issue:10

    Topics: Animals; Autophagy; Deoxyadenosines; Diabetic Nephropathies; Disease Models, Animal; Male; Random Allocation; Rats; Rats, Wistar

2019
Peripheral administration of translation inhibitors reverses increased hyperalgesia in a model of chronic pain in the rat.
    The journal of pain, 2013, Volume: 14, Issue:7

    Topics: Animals; Chronic Pain; Deoxyadenosines; Disease Models, Animal; Hyperalgesia; Male; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Sirolimus

2013
Cordycepin, 3'-deoxyadenosine, prevents rat hearts from ischemia/reperfusion injury via activation of Akt/GSK-3β/p70S6K signaling pathway and HO-1 expression.
    Cardiovascular toxicology, 2014, Volume: 14, Issue:1

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Cardiotonic Agents; Cordyceps; Cytoprotection; Deoxyadenosines; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Heme Oxygenase (Decyclizing); Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Time Factors; Ventricular Function, Left; Ventricular Pressure

2014
Cordycepin induces S phase arrest and apoptosis in human gallbladder cancer cells.
    Molecules (Basel, Switzerland), 2014, Jul-31, Volume: 19, Issue:8

    Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Deoxyadenosines; Disease Models, Animal; Gallbladder Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Membrane Potential, Mitochondrial; Mice; Molecular Structure; Proto-Oncogene Proteins c-bcl-2; S Phase Cell Cycle Checkpoints; Tumor Burden; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays

2014
The effects of cordycepin on ovalbumin-induced allergic inflammation by strengthening Treg response and suppressing Th17 responses in ovalbumin-sensitized mice.
    Inflammation, 2015, Volume: 38, Issue:3

    Topics: Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Deoxyadenosines; Dexamethasone; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Eosinophilia; Eosinophils; Female; Forkhead Transcription Factors; Immunoglobulin E; Inflammation; Interleukin-10; Interleukin-17; Mice; Mice, Inbred BALB C; Nuclear Receptor Subfamily 1, Group F, Member 3; Ovalbumin; Random Allocation; T-Lymphocytes, Regulatory; Th17 Cells

2015
3'-Deoxyadenosine (Cordycepin) Produces a Rapid and Robust Antidepressant Effect via Enhancing Prefrontal AMPA Receptor Signaling Pathway.
    The international journal of neuropsychopharmacology, 2016, Volume: 19, Issue:4

    Topics: Animals; Antidepressive Agents; Benzodiazepines; Deoxyadenosines; Depressive Disorder; Disease Models, Animal; Excitatory Amino Acid Antagonists; Hippocampus; Imipramine; Male; Mice; Motor Activity; Phosphorylation; Prefrontal Cortex; Random Allocation; Receptors, AMPA; Synapses; Time Factors; Treatment Outcome

2016
Cordycepin attenuates traumatic brain injury-induced impairments of blood-brain barrier integrity in rats.
    Brain research bulletin, 2016, Volume: 127

    Topics: Animals; Blood-Brain Barrier; Brain Injuries, Traumatic; Deoxyadenosines; Disease Models, Animal; Dose-Response Relationship, Drug; Interleukin-10; Interleukin-1beta; Matrix Metalloproteinase 9; NADPH Oxidases; Neuroprotective Agents; Nitric Oxide Synthase Type II; Occludin; Rats, Sprague-Dawley; Zonula Occludens-1 Protein

2016
Cordycepin disrupts leukemia association with mesenchymal stromal cells and eliminates leukemia stem cell activity.
    Scientific reports, 2017, 03-07, Volume: 7

    Topics: Animals; Antineoplastic Agents; Cell Adhesion; Deoxyadenosines; Disease Models, Animal; Humans; K562 Cells; Leukemia; Mesenchymal Stem Cells; Mice; Survival Analysis; Treatment Outcome; U937 Cells

2017
Cordycepin inhibits vascular smooth muscle cell proliferation.
    European journal of pharmacology, 2008, Nov-12, Volume: 597, Issue:1-3

    Topics: Animals; Basigin; Cardiovascular Agents; Carotid Artery Injuries; Catheterization; Cell Movement; Cell Proliferation; Cells, Cultured; Collagen Type I; Cyclooxygenase 2; Deoxyadenosines; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Rats, Sprague-Dawley

2008
Beneficial effects of cordycepin on metabolic profiles of liver and plasma from hyperlipidemic hamsters.
    Journal of Asian natural products research, 2011, Volume: 13, Issue:6

    Topics: Animals; Cholesterol; Cricetinae; Deoxyadenosines; Disease Models, Animal; Hyperlipidemias; Liver; Male; Metabolome; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Simvastatin; Triglycerides

2011
Treatment of African trypanosomiasis with cordycepin and adenosine deaminase inhibitors in a mouse model.
    The Journal of infectious diseases, 2005, Nov-01, Volume: 192, Issue:9

    Topics: Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Antiprotozoal Agents; Deoxyadenosines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Therapy, Combination; Injections, Intraperitoneal; Leishmania; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Trypanosoma brucei brucei; Trypanosoma cruzi; Trypanosomiasis, African

2005
Antifungal activity of 3'-deoxyadenosine (cordycepin).
    Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:6

    Topics: Adenosine Deaminase Inhibitors; Animals; Antifungal Agents; Candidiasis; Deoxyadenosines; Disease Models, Animal; Drug Interactions; Drug Resistance, Microbial; Enzyme Inhibitors; Male; Mice; Mice, Inbred ICR; Pentostatin; Survival Analysis

1998