concanavalin-a and Meniere-Disease

concanavalin-a has been researched along with Meniere-Disease* in 2 studies

Other Studies

2 other study(ies) available for concanavalin-a and Meniere-Disease

Article	Year
[Lymphocytes of patients with auto-immune deafness present type II collagen hyporeactivity in the presence of the pineal hormone melatonin]. Acta otorrinolaringologica espanola, 2000, Volume: 51, Issue:4 A study was made of the behavior of peripheral blood lymphocytes in healthy controls and patients with various types of hearing loss. Hearing loss of auto-immune origin was studied in the presence and absence of melatonin, activated or not by concanavalin A. In patients with auto-immune hearing loss, lymphocytes showed hyporeactivity to type II collagen in terms of proliferative activity in the presence of concavalin A. Hyporeactivity was especially relevant in melatonin-incubated cells. In different nosologic entities, lymphocyte hyporeactivity to type II collagen was similar in bilateral sensorineural hearing loss, Ménière's disease and otosclerosis. We conclude that the lymphocytes of patients with autoimmune hearing loss showed hyporeactivity to type II collagen when compared to lymphocytes from control subjects. This hyporeactivity was revealed when lymphocytes were activated in the presence of melatonin. Topics: Adolescent; Adult; Aged; Autoimmune Diseases; Cell Movement; Collagen; Concanavalin A; Deafness; Female; Humans; Lymphocytes; Male; Melatonin; Meniere Disease; Middle Aged; Pineal Gland	2000
Melatonin induces hyporeactivity caused by type II collagen in peripheral blood lymphocytes from patients with autoimmune hearing losses. Neuroscience letters, 1997, Dec-12, Volume: 239, Issue:1 We have studied the behavior of peripheral blood lymphocytes in healthy controls and in patients with various hearing losses. These hearing losses were of an autoimmune origin in which type II collagen and melatonin were either present or absent, activated or not with concanavalin A (Con A). In patients with autoimmune hearing losses, the results showed lymphocytes that displayed hyporeactivity to type II collagen in terms of their proliferative activity in the presence of Con A. The hyporeactivity is specially relevant in those cells which are melatonin incubated. When different nosologic entities were studied, we observed similar lymphocyte hyporeactivity to type II collagen in bilateral sensorineural hearing loss, Ménière's disease and otosclerosis. We conclude that in the lymphocytes of patients with autoimmune hearing losses, there is hyporeactivity to type II collagen when compared to the hyporeactivity of lymphocytes in control groups. This hyporeactivity is revealed when the lymphocytes are activated in the presence of melatonin. Topics: Adolescent; Adult; Aged; Autoimmune Diseases; Case-Control Studies; Cell Division; Child; Collagen; Concanavalin A; Deafness; Female; Humans; Lymphocytes; Male; Melatonin; Meniere Disease; Middle Aged; Otosclerosis	1997

Article

Year

[Lymphocytes of patients with auto-immune deafness present type II collagen hyporeactivity in the presence of the pineal hormone melatonin].

Acta otorrinolaringologica espanola, 2000, Volume: 51, Issue:4

A study was made of the behavior of peripheral blood lymphocytes in healthy controls and patients with various types of hearing loss. Hearing loss of auto-immune origin was studied in the presence and absence of melatonin, activated or not by concanavalin A. In patients with auto-immune hearing loss, lymphocytes showed hyporeactivity to type II collagen in terms of proliferative activity in the presence of concavalin A. Hyporeactivity was especially relevant in melatonin-incubated cells. In different nosologic entities, lymphocyte hyporeactivity to type II collagen was similar in bilateral sensorineural hearing loss, Ménière's disease and otosclerosis. We conclude that the lymphocytes of patients with autoimmune hearing loss showed hyporeactivity to type II collagen when compared to lymphocytes from control subjects. This hyporeactivity was revealed when lymphocytes were activated in the presence of melatonin.

Topics: Adolescent; Adult; Aged; Autoimmune Diseases; Cell Movement; Collagen; Concanavalin A; Deafness; Female; Humans; Lymphocytes; Male; Melatonin; Meniere Disease; Middle Aged; Pineal Gland

2000

Melatonin induces hyporeactivity caused by type II collagen in peripheral blood lymphocytes from patients with autoimmune hearing losses.

Neuroscience letters, 1997, Dec-12, Volume: 239, Issue:1

We have studied the behavior of peripheral blood lymphocytes in healthy controls and in patients with various hearing losses. These hearing losses were of an autoimmune origin in which type II collagen and melatonin were either present or absent, activated or not with concanavalin A (Con A). In patients with autoimmune hearing losses, the results showed lymphocytes that displayed hyporeactivity to type II collagen in terms of their proliferative activity in the presence of Con A. The hyporeactivity is specially relevant in those cells which are melatonin incubated. When different nosologic entities were studied, we observed similar lymphocyte hyporeactivity to type II collagen in bilateral sensorineural hearing loss, Ménière's disease and otosclerosis. We conclude that in the lymphocytes of patients with autoimmune hearing losses, there is hyporeactivity to type II collagen when compared to the hyporeactivity of lymphocytes in control groups. This hyporeactivity is revealed when the lymphocytes are activated in the presence of melatonin.

Topics: Adolescent; Adult; Aged; Autoimmune Diseases; Case-Control Studies; Cell Division; Child; Collagen; Concanavalin A; Deafness; Female; Humans; Lymphocytes; Male; Melatonin; Meniere Disease; Middle Aged; Otosclerosis

1997