concanavalin-a and Erythema

concanavalin-a has been researched along with Erythema* in 2 studies

Other Studies

2 other study(ies) available for concanavalin-a and Erythema

ArticleYear
Streptococcal and staphylococcal superantigen-induced lymphocytic arteritis in a local type experimental model: comparison with acute vasculitis in the Arthus reaction.
    The Journal of laboratory and clinical medicine, 1998, Volume: 131, Issue:1

    Many pathogenic bacteria produce superantigenic exotoxins. To study their pathogenetic role, in particular to test whether these toxins are able to induce vasculitis, we developed a local-type experimental model in rabbits. Toxins were injected along the intermediate auricular artery of the ear. The histology of ear skin, including the artery, was examined after single or repeated injections. Repeated injections of streptococcal erythrogenic toxins produced chronic-type arteritis characteristic of lymphocytic infiltration, whereas single injection induced no acute-type vasculitis. Staphylococcal enterotoxin B and toxic shock syndrome toxin-1 also induced the same type of arteritis, although weaker in degree. In human patients these lesions are similar to those of Kawasaki disease, a systemic vasculitis with unknown etiology. The Arthus reaction to human serum albumin in immunized rabbits included acute-type vasculitis similar to polyarteritis nodosa when examined in this model. Microvasculitis lesions similar to leukoclastic vasculitis were combined in the Arthus reaction but not in the superantigen-induced lesions. Our experimental model described here is widely applicable to the study of the etiology and pathogenesis of human diseases involving vasculitis lesions.

    Topics: Animals; Antigens, Bacterial; Arteritis; Arthus Reaction; Bacterial Toxins; Concanavalin A; Erythema; Exotoxins; Female; Rabbits; Skin; Staphylococcus; Streptococcus; Superantigens; Vasculitis

1998
Human skin responses to products of concanavalin A-activated lymphocytes.
    Journal of immunology (Baltimore, Md. : 1950), 1973, Volume: 111, Issue:2

    Topics: Candidiasis, Cutaneous; Cell Migration Inhibition; Concanavalin A; Erythema; Humans; Hypersensitivity, Delayed; Injections, Intradermal; Lectins; Lymphocytes; Macrophages; Sarcoidosis; Skin; Skin Diseases; Skin Tests

1973