concanavalin-a and Disease

concanavalin-a has been researched along with Disease* in 2 studies

Other Studies

2 other study(ies) available for concanavalin-a and Disease

ArticleYear
Fullerol-fluorescein isothiocyanate-concanavalin agglutinin phosphorescent sensor for the detection of alpha-fetoprotein and forecast of human diseases.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2013, Volume: 115

    Based on the reaction of the active -OH group in fullerol (F) with the dissociated -COOH group in fluorescein isothiocyanate (FITC) to form an F-FITC and the enhanced effect of N, N-dimethylaniline (DMA) on phosphorescence signal of F-FITC, a new phosphorescent labeling reagent (DMA-F-FITC) was developed. What's more, a phosphorescent sensor for the determination of alpha-fetoprotein variant (AFP-V) has been designed via the coupling technique of the high sensitivity for affinity adsorption-solid substrate-room temperature phosphorimetry (AA-SS-RTP) with the strong specificity reaction between DMA-F-FITC-Con A and AFP-V. The DMA-F-FITC increased the number of luminescent molecules in the biological target which improved the sensitivity of phosphorescent sensor. The proposed sensor was responsive, simple, selective and sensitive, and it has been applied to the determination of trace AFP-V in human serum and the forecast of human diseases using phosphorescence emission wavelength of F or FITC, with the results agreed well with those obtained by enzyme-linked immunoassay (ELISA). Meanwhile, the mechanisms for the labeling reaction and the sensing detection of AFP-V were discussed.

    Topics: alpha-Fetoproteins; Aniline Compounds; Biosensing Techniques; Concanavalin A; Disease; Fluorescein-5-isothiocyanate; Fullerenes; Humans; Humidity; Indicators and Reagents; Limit of Detection; Luminescence; Oxygen; Temperature; Time Factors

2013
The dynamics of biomembranes and implications for membrane disease.
    Biochemical Society transactions, 1980, Volume: 8, Issue:6

    Topics: Animals; Calcium-Transporting ATPases; Cell Division; Cholesterol; Concanavalin A; Disease; Humans; Kinetics; Membrane Fluidity; Membrane Lipids; Membrane Proteins; Membranes; Phospholipids; Rats; Sarcoplasmic Reticulum; Thermodynamics

1980