concanavalin-a and Carcinoma--Basal-Cell

Topics: Adult; Aged; Carcinoma, Basal Cell; Concanavalin A; Humans; Lymphocyte Activation; Middle Aged; Neoplasms, Multiple Primary; Skin Neoplasms

Differences in the cell surface of malignant cells, as compared with normal cells, are believed to be characteristic of many features of tumor cell behaviour. We have obtained evidence suggesting that solid and superficial basal cell carcinomas lack immuno-reactive beta-2-microglobulin (beta-2-m) on the cell surface, in contrast to normal epidermis and that of various non-malignant dermatoses, including basal cell papillomas.

Topics: Antibodies, Neoplasm; beta 2-Microglobulin; Beta-Globulins; Carcinoma, Basal Cell; Cell Membrane; Concanavalin A; Fluorescent Antibody Technique; Humans; Pemphigus; Skin Neoplasms

Topics: Animals; Carcinoma, Basal Cell; Carcinoma, Ehrlich Tumor; Cell Adhesion; Cell Fusion; Cells, Cultured; Concanavalin A; Humans; Macrophages; Mice; Microscopy, Electron; Phagocytosis; Radiation Effects; Skin; Skin Neoplasms; Staining and Labeling; Time Factors