combivent-respimat and Vomiting

Glucagon, a hormone secreted by pancreatic alpha cells, causes bronchial smooth muscle relaxation by activating the synthesis of cyclic adenosine monophosphate. It was studied in the 1980s and 1990s as a treatment option for the management of asthma but has since not been evaluated. Data to support its use are limited, but it may serve as a last-line agent for refractory asthma exacerbation. Here we describe 4 cases in which intravenous glucagon was used to manage severe, refractory asthma exacerbation in the emergency department.

Topics: Administration, Intravenous; Adult; Albuterol, Ipratropium Drug Combination; Anti-Asthmatic Agents; Antiemetics; Asthma; Continuous Positive Airway Pressure; Disease Progression; Female; Glucagon; Hormones; Humans; Male; Middle Aged; Vomiting