colistin and Syphilis

colistin has been researched along with Syphilis* in 2 studies

Reviews

1 review(s) available for colistin and Syphilis

ArticleYear
Biopharmacology of syphilotherapy.
    Journal of the American Venereal Disease Association, 1976, Volume: 3, Issue:2 Pt 2

    Data collected from experimental rabbit syphilis and from in vitro studies with nonpathogenic treponemes can be extended only with great caution to human syphilis. The following tentative conclusions may be drawn: penicillin acts on Treponema pallidum by interfering with cell wall synthesis. Concentrations of penicillin greater than 0.1 mug/ml do not have increased treponemicidal effect. Regimens producing penicillinemia for at least 8 days are considerably more efficient than treatment yielding high peak serum levels of brief duration. Treponemal residence in antibiotic-protected sites increases the need for long duration therapy. Other antibiotics are less effective than penicillin, and patterns of antibiotic interaction against treponemes do not match those seen with other bacteria.

    Topics: Aminoglycosides; Animals; Anterior Chamber; Anti-Bacterial Agents; Bacitracin; Cephalosporins; Chloramphenicol; Colistin; Dose-Response Relationship, Drug; Drug Therapy, Combination; Erythromycin; Humans; L Forms; Male; Metronidazole; Penicillin G; Penicillin Resistance; Penicillins; Rabbits; Syphilis; Tetracyclines; Treponema pallidum

1976

Other Studies

1 other study(ies) available for colistin and Syphilis

ArticleYear
Colistin (colistinmethanesulphonate) in experimental syphilis.
    The British journal of venereal diseases, 1963, Volume: 39

    Topics: Colistin; Syphilis

1963