colistin and Postoperative-Complications

We present a case of Gram-negative neurosurgical meningitis in a neonate, refractory to optimal intravenous therapy and removal of ventriculoperitoneal shunt. Cerebrospinal fluid was sterilized within 24 hours using intraventricular colistin. This is the first report of intraventricular colistin use in neonatal meningitis caused by Enterobacter cloacae.

Topics: Anti-Bacterial Agents; Colistin; Gram-Negative Bacterial Infections; Humans; Infant, Newborn; Male; Meningitis; Neurosurgical Procedures; Postoperative Complications; Treatment Outcome; Ventriculoperitoneal Shunt

Post-neurosurgical nosocomial meningitis has become an important subgroup of bacterial meningitis in the hospital setting. The increase in meningitis caused by multidrug-resistant (MDR) Acinetobacter baumannii has resulted in a significant reduction in available treatment options.. We report the case of a 36-year-old man with a complex craniofacial trauma, who developed a nosocomial meningitis due to MDR A. baumannii that was cured by intrathecal colistin. The case is contextualized among all the published cases of Acinetobacter meningitis treated with topical colistin found through a MEDLINE search of the literature. To date, including the present case, eight reported cases of Acinetobacter meningitis have been treated with colistin administered by an intrathecal route and 24 by an intraventricular route. The daily dose of colistin used ranged from 1.6 mg every 24 h to 20 mg every 24 h in adult patients. The median time necessary to obtain cerebrospinal fluid sterilization was 4.1 days, and treatment was always successful even if in two cases Acinetobacter meningitis relapsed. Toxicity probably or possibly related to the topical administration of colistin was noted in five out of the 32 patients.. Topical colistin can be an effective and safe treatment for MDR Acinetobacter meningitis.

Topics: Acinetobacter baumannii; Acinetobacter Infections; Adult; Anti-Bacterial Agents; Colistin; Craniocerebral Trauma; Drug Resistance, Multiple, Bacterial; Humans; Injections, Spinal; Male; Meningitis, Bacterial; Postoperative Complications; Treatment Outcome

Intrathecal colistin (Polymxin E) is becoming an important option for the treatment of post-neurosurgical meningitis caused by multidrug resistant (MDR) Acinetobacter baumannii. We report a case of 28-year-old man who developed meningitis due to MDR A. baumannii associated with an external ventricular drain. The patient was cured using a 4-week course of intrathecal colistin 3.2 mg via external ventricular drain (EVD) daily without any serious side effects.

Topics: Acinetobacter baumannii; Acinetobacter Infections; Adult; Anti-Bacterial Agents; Colistin; Craniocerebral Trauma; Drug Resistance, Multiple, Bacterial; Humans; Injections, Spinal; Male; Meningitis, Bacterial; Postoperative Complications

Nosocomial infections with organisms resistant to multiple antibiotic agents represent an evolving challenge in the intensive care setting, particularly in patients requiring surgical diversion of cerebrospinal fluid. The authors present the case of a 51-year-old woman who endured protracted hospitalization and required multiple surgeries including placement of a ventriculoperitoneal shunt. The shunt subsequently became colonized with Pseudomonas aeruginosa, which demonstrated intermediate sensitivity to amikacin and full resistance to all other antibiotics tested 'After failing to respond to intravenous imipenem as well as intravenous and intrathecal amikacin, the patient was successfully treated with intravenous and intrathecal colistin. Colistin is a polymyxin-type antibiotic, rarely used outside of topical application because of reported nephrotoxicity associated with parenteral administration. With activity limited to Gram-negative organisms, colistin is bactericidal by directly disrupting the structure of cell membranes. Authors of a few case reports in the literature have described successful treatment of various ventriculitis with the intrathecal administration of colistin. With bacterial resistances outpacing the pharmaceutical industry's ability to develop novel antibiotics, colistin represents an important alternative in situations involving multidrug-resistant organisms.

Topics: Anti-Bacterial Agents; Cerebral Ventricles; Cerebrospinal Fluid Shunts; Colistin; Cross Infection; Drug Resistance, Multiple; Encephalitis; Female; Humans; Injections, Spinal; Middle Aged; Postoperative Complications; Pseudomonas Infections

Topics: Adolescent; Adult; Amphotericin B; Ampicillin; Cadaver; Cephalosporins; Cephradine; Clinical Trials as Topic; Colistin; Drug Therapy, Combination; Humans; Kidney Transplantation; Middle Aged; Postoperative Complications; Urinary Tract Infections

Topics: Adult; Clinical Trials as Topic; Colistin; Colitis, Ulcerative; Colon; Crohn Disease; Diet Therapy; Feces; Female; Humans; Intestinal Obstruction; Laparotomy; Male; Middle Aged; Peritoneal Cavity; Postoperative Complications; Preoperative Care; Prospective Studies; Sulfathiazoles; Surgical Wound Infection

Acinetobacter baumannii meningitis and ventriculitis are difficult issues, because of the low diffusion of antibiotics in the cerebrospinal fluid and bacterial multidrug resistance. The presence of an infected intraventricular hematoma, constituting an equivalent of undrained abscess, may promote biofilm formation and failure of medical treatment.. In this case of ventriculostomy-related infection after ventricular hemorrhage, Acinetobacter baumannii was sensitive only to colistin and tigecycline. Despite a combination therapy involving intraventricular injections of colistin, we observed clinical and bacteriologic failure. Therefore, at day 4 of antibiotic therapy, we performed intraventricular fibrinolysis, which dissolved the clot, enabling sterilization of the cerebrospinal fluid after 48 hours.. This clinical case suggests the usefulness of intraventricular fibrinolysis to lyse the clot and optimize the action of antibiotics.

Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Colistin; Drug Resistance, Multiple, Bacterial; Female; Humans; Middle Aged; Postoperative Complications; Thrombolytic Therapy; Tigecycline; Ventriculostomy

Post-surgical intra-abdominal infections (IAIs) due to carbapenem-resistant Acinetobacter baumannii (CRAB) are difficult to treat due to suboptimal peritoneal penetrations of several antimicrobial agents. Tigecycline has favorable outcomes of treating IAIs due to multidrug-resistant organisms but occurrence of breakthrough bacteremia has been observed because this agent has low serum level. Colistin has in vitro activity against CRAB but data on treatment of IAIs is limited due to poor peritoneal penetration. The purpose of this retrospective study is to explore the outcomes of adjunctive intravenous (IV) colistin to IV tigecycline in the treatment of IAIs caused by CRAB. Of 28 patients with non-bacteremic post-surgical IAIs due to CRAB, 14 patients received IV tigecycline alone and 14 patients received IV tigecycline with IV colistin. The 14-day, 30-day, in-hospital mortality rates, the rate of breakthrough bacteremia and the rate of bacterial eradication were not significantly different. The adjunctive therapy of IV colistin was associated with significantly higher rates of renal complications (10/14) than those receiving IV tigecycline alone (3/14) (P value = 0.023). In addition, the patients receiving adjunctive IV colistin had significantly more unfavorable non-clinical outcomes including longer length of hospital stay (P value = 0.049) and higher antimicrobial cost (P value = 0.008) and non-antimicrobial costs (P value = 0.037). In this study, adjunctive IV colistin to conventional IV tigecycline in the treatment of non-bacteremic post-surgical IAIs caused by CRAB did not yield clinical benefit but caused higher renal complication and unfavorable non-clinical outcomes.

Topics: Acinetobacter baumannii; Acinetobacter Infections; Administration, Intravenous; Adult; Carbapenems; Colistin; Drug Resistance, Microbial; Female; Humans; Intraabdominal Infections; Male; Middle Aged; Postoperative Complications; Renal Insufficiency; Retrospective Studies; Tigecycline

Topics: Acinetobacter baumannii; Acinetobacter Infections; Adolescent; Anti-Bacterial Agents; Brain Injuries, Traumatic; Cerebrospinal Fluid Shunts; Colistin; Coma; Craniotomy; Cross Infection; Drug Resistance, Multiple, Bacterial; Humans; Male; Meningitis, Bacterial; Postoperative Complications; Tigecycline

Acinetobacter baumannii can cause serious infection in susceptible patients, but little has been published regarding risk factors for infection and outcomes in solid organ transplant (SOT) recipients.. We identified A. baumannii infection among adult SOT recipients that occurred between January 2001 and March 31, 2008 at a Chicago transplant center and evaluated characteristics of these infections and outcomes.. Thirty-three individuals developed A. baumannii infection during the study period. Seventy-nine percent had healthcare-associated infection with respiratory tract as the most common site of infection (64%). Eighty-two percent of patients had received antibiotics within two wk prior to A. baumannii infection and multidrug resistance (MDR) or extensive resistance (XDR) occurred in 85%. The median time to onset of infection was five months after transplant. The 30-d mortality was 24% and was associated with XDR. Administration of an appropriate antibiotic within three d was associated with lower 30-d mortality (OR 0.16, p = 0.047). All isolates tested against colistin were susceptible.. SOT recipients with A. baumannii infection had high mortality associated with delay in appropriate antibiotic therapy and XDR organisms. The use of colistin-containing treatment regimens should be considered in these patients when A. baumannii infection is suspected or identified in patients who have received prior antibiotics.

Topics: Acinetobacter baumannii; Acinetobacter Infections; Adult; Aged; Anti-Bacterial Agents; Colistin; Cross Infection; Female; Humans; Immunocompromised Host; Logistic Models; Male; Middle Aged; Organ Transplantation; Postoperative Complications; Retrospective Studies; Risk Factors

Bacterial infections are major causes of early morbidity and mortality after liver transplantation. Selective digestive decontamination (SDD) can be used pre-operatively for living-donor liver transplant (LD-LT), but its role in this setting remains controversial.. To evaluate this strategy, we retrospectively analyzed a cohort of consecutive LD-LTs performed in our center from March 2007 to February 2011 and compared the incidence and nature of early infectious complications, length of intensive care unit stay and hospitalization, antibiotic use, and emergence of resistant bacteria in patients with or without SDD prophylaxis.. Of 148 LD-LTs in the study period, 111 received SDD prophylaxis while 37 did not. In a multivariate model, the independent factors associated with an increased risk of early post-transplant infections were length of postoperative mechanical ventilation (for every additional day odds ratio [OR] = 2.37, 95% confidence interval [CI] 1.4-4.0; P = 0.002), and choledochojejunostomy (OR = 4.5, 95% CI 1.95-10.5; P < 0.001). Use of SDD did not affect the rate or distribution of infectious complications, duration of hospitalization, antibiotic use, or acquisition of resistant bacteria (OR = 3.52, 95% CI 0.43-15.17; P = 0.376).. In conclusion, the use of SDD prophylaxis in LD-LT was not beneficial and should be avoided, as it offers no advantage and could potentiate the emergence of multidrug-resistant organisms.

Topics: Adult; Anti-Bacterial Agents; Bacterial Infections; Colistin; Decontamination; Digestive System; Drug Therapy, Combination; Female; Gentamicins; Humans; Liver Transplantation; Living Donors; Male; Middle Aged; Odds Ratio; Postoperative Complications; Retrospective Studies; Young Adult

Topics: Administration, Oral; Administration, Topical; Adrenal Cortex Hormones; Amoxicillin-Potassium Clavulanate Combination; Bacitracin; Bacterial Infections; Child, Preschool; Colistin; Germany; Humans; Hydrocortisone; Middle Ear Ventilation; Otitis Media, Suppurative; Postoperative Complications; Randomized Controlled Trials as Topic

Acinetobacter baumannii (AB) nosocomial infections, especially those due to multi-drug resistant (MDR) strains, are increasingly detected. We report a case of a 42-year-old male patient affected by low-grade ependymoma who developed AB-MDR post-neurosurgical ventriculitis. Initially, because of in vitro susceptibility, we used a combination of intravenous colistin and tigecycline. This treatment resulted in the improvement of the patient's initial condition. However, soon after, the infection relapsed; tigecycline was stopped and treatment with intrathecal colistin was initiated. Cure was achieved by continuing this treatment for approximately three weeks, without adverse effects.

Topics: Acinetobacter baumannii; Acinetobacter Infections; Adult; Anti-Bacterial Agents; Brain Neoplasms; Cerebral Ventriculitis; Colistin; Drug Resistance, Multiple, Bacterial; Ependymoma; Humans; Injections, Intravenous; Injections, Spinal; Male; Postoperative Complications

Cerebrospinal fluid (CSF) shunts significantly improve the quality of life in patients with acute hydrocephalus. However, infections associated with a CSF shunt constitute a severe complication with high morbidity and mortality. We describe a case of CFS shunt infection cured with intrathecal colistin.

Topics: Anti-Bacterial Agents; Cell Membrane; Cerebral Hemorrhage; Cerebral Ventriculitis; Cerebrospinal Fluid Shunts; Colistin; Drug Resistance, Multiple, Bacterial; Humans; Hydrocephalus; Injections, Spinal; Male; Middle Aged; Postoperative Complications; Prosthesis-Related Infections; Pseudomonas aeruginosa; Pseudomonas Infections

Meropenem (MEM; 2 g/8 hr; minimum inhibitory concentration [MIC] = 256 mg/L) plus sulbactam (SUL; 1 g/8 hr; MIC = 128 mg/L) (two-drug-therapy period), and subsequent additional intravenous colistin (COL; 2.5 mg/kg/12 hr) and intraventricular (COL, 5 mg/day; MIC = 1 mg/L) (three-drug-therapy period) were sequentially used in a patient with postneurosurgery bacteremic meningitis due to a multidrug-resistant Acinetobacter baumannii (MDRAB) isolate (AB(1)). We detected 4- to 32-fold increases in peak or trough cerebrospinal fluid bactericidal titer and serum bactericidal titer in three-drug-therapy period when comparing to those in two-drug-therapy period. The time-kill study with MEM, SUL, and COL alone or varied combinations (all at 1 x MIC) against AB(1) and another genetically nonrelated MDRAB isolate (AB(134) [MICs of MEM = 64 mg/L, SUL = 16 mg/L, and COL = 1 mg/L]) was performed. The two-drug combinations (MEM + SUL, MEM + COL, and SUL + COL) each elicited different inhibitory effect on AB(1) and AB(134) at 6 hr. Bacterial regrowth at 24 hr was observed in the experiments in which the MDRAB isolate was inhibited earlier by COL alone (AB(1) and AB(134)), by MEM plus SUL (AB(1)), and by MEM plus COL (AB(134)), but not in SUL plus COL, and MEM + SUL + COL. Combined use of COL with MEM and/or SUL may provide good therapeutic options, even though MEM and SUL are in vitro resistance to the MDRAB.

Topics: Acinetobacter baumannii; Acinetobacter Infections; Aged; Anti-Bacterial Agents; Bacteremia; Colistin; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Humans; Male; Meningitis, Bacterial; Meropenem; Microbial Sensitivity Tests; Neurosurgical Procedures; Postoperative Complications; Sulbactam; Thienamycins; Time Factors

Post-surgical meningitis and/or ventriculitis caused by Gram-negative bacteria may be difficult to treat due to the emergence of multiresistant strains. Two patients with multiresistant Acinetobacter baumannii central nervous system infection, successfully treated with either intravenous and/or intraventricular colistin are presented. Unresolved issues such as dose and duration of intraventricular colistin are discussed.

Topics: Acinetobacter baumannii; Acinetobacter Infections; Adult; Aneurysm, Ruptured; Anti-Bacterial Agents; Colistin; Craniocerebral Trauma; Cross Infection; Device Removal; Drug Resistance, Multiple, Bacterial; Female; Humans; Hydrocephalus; Injections, Intraventricular; Intracranial Aneurysm; Male; Postoperative Complications; Ventriculoperitoneal Shunt

Multidrug-resistant Acinetobacter baumannii is an emergent nosocomial pathogen. A 61-year-old woman developed meningitis caused by MDRAB 27 days after receiving a surgical intervention for invasive meningioma. The patient failed to respond to high doses of meropenem and sulbactam treatment and the organism persisted in the cerebrospinal fluids for two months. The regimen was changed to intravenous and intrathecal colistin for 28 days and the patient responded well. Administration of colistin both intravenously and intrathecally could be a suitable option as a salvage therapy for meningitis due to multidrug-resistant A. baumannii.

Topics: Acinetobacter baumannii; Acinetobacter Infections; Cerebrospinal Fluid; Colistin; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Female; Humans; Infusions, Intravenous; Injections, Spinal; Meningeal Neoplasms; Meningioma; Meningitis, Bacterial; Middle Aged; Postoperative Complications

Nosocomial infections due to MDR P. aeruginosa are an increasing problem. Therapeutical options are few. We describe two haematological patients with severe neutropenia and systemic infection due to MDR P. aeruginosa treated successfully with colistin plus ceftazidime. Severe adverse events were not described.

Topics: Acute Disease; Adrenal Cortex Hormones; Aged; Anemia, Refractory, with Excess of Blasts; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Ceftazidime; Colistin; Colitis; Disease Susceptibility; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Fatal Outcome; Female; Humans; Infusions, Intravenous; Leukemia, Myeloid; Lymphoma, Non-Hodgkin; Male; Middle Aged; Neoplasms, Second Primary; Peritonitis; Postoperative Complications; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pseudomonas Infections; Radiation Injuries; Spinal Neoplasms; Typhlitis

Topics: Anti-Bacterial Agents; Cerebral Ventricles; Colistin; Gram-Positive Bacterial Infections; Humans; Injections, Intraventricular; Postoperative Complications; Safety

Topics: Acinetobacter Infections; Anti-Bacterial Agents; Colistin; Female; Humans; Injections, Spinal; Meningioma; Meningitis, Bacterial; Middle Aged; Neurosurgical Procedures; Postoperative Complications

Topics: Animals; Bacteria, Aerobic; Bacterial Infections; Colistin; Drug Therapy, Combination; Enterobacteriaceae; Female; Intestine, Small; Liver; Liver Transplantation; Lung; Lymph Nodes; Mycoses; Nystatin; Postoperative Complications; Spleen; Swine; Tobramycin; Transplantation, Autologous; Vancomycin

Topics: Adolescent; Adult; Aerobiosis; Bacterial Infections; Candida; Candidiasis; Child; Colistin; Gentamicins; Gram-Negative Bacteria; Humans; Intestines; Liver Transplantation; Nystatin; Pharynx; Postoperative Complications; Rectum

Topics: Adult; Aortic Valve; Colistin; Drug Therapy, Combination; Endocarditis, Bacterial; Heart Valve Prosthesis; Humans; Male; Postoperative Complications; Pseudomonas Infections; Rifampin; Tobramycin

Topics: Anti-Bacterial Agents; Colistin; Colon; Drug Resistance, Microbial; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Intestinal Diseases; Kanamycin; Postoperative Complications; Preoperative Care; Rectum

Topics: Acute Kidney Injury; Aged; Anti-Bacterial Agents; Burns; Cephalothin; Colistin; Drug Therapy, Combination; Gentamicins; Humans; Male; Middle Aged; Peritonitis; Postoperative Complications; Pseudomonas Infections

Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Child; Colistin; Drainage; Female; Gentamicins; Humans; Hypotension; Male; Middle Aged; Peritoneal Dialysis; Postoperative Complications; Renal Dialysis; Sepsis

Subphrenic abscess is still a significant hazard which complicates surgical procedures as well as certain abdominal catastrophes. This is a report of 88 patients with subphrenic abscess at St. Vincent's Hospital and Medical Center of New York from 1954 through 1971. There were 46 males and 42 females, ranging from 2 to 88 years. Operations on the stomach, duodenum and biliary tract were the major causes. The causative organisms in order of frequency were: E coli (41.6%), Staphylococcus (41.6%), Aerobacter aerogenes (23.3%), Proteus (20%), Streptococci (18.3%) and Pseudomonas (8.3%). Penicillin and tetracycline, the antibiotics most commonly chosen on an empiric basis, proved effective in only 38% of cases. On the other hand, kanamycin, chloramphenicol and cephalothin were effective in 90%, 85% and 70% of cases respectively. The overall mortality rate was 15%. Nine of the 21 patients (42.8%) treated with antibiotics alone died while 11 of 67 patients (10.6%) treated with antibiotics and surgical drainage died. Some of the latter deaths occurred in patients treated with prolonged antibiotic therapy and operated on only as a last resort. In this series subphrenic abscess was best treated by early surgical drainage combined with the use of appropriate antibiotics.

Topics: Abdominal Injuries; Adolescent; Adult; Aged; Anti-Bacterial Agents; Child; Child, Preschool; Chloramphenicol; Colistin; Drug Resistance, Microbial; Escherichia coli Infections; Female; Humans; Infant; Kanamycin; Male; Microbial Sensitivity Tests; Middle Aged; Postoperative Complications; Radiography; Staphylococcal Infections; Subphrenic Abscess; Surgical Procedures, Operative

Pseudomonas aeruginosa was isolated from the sputum of 63 patients. In 34 the organism was a commensal, in 14 it was causing chronic suppuration, and in 10 had interfered with antibiotics directed against other organisms and was thus indirectly pathogenic. In five patients, all of whom died, the organism could have been acting as an acute pathogen. Attempts should be made to determine the nature of the organism's pathogenicity in a given patient and appropriate therapy withheld or administered accordingly.

Topics: Bronchitis; Carbenicillin; Colistin; Gentamicins; Humans; Lung Diseases; Postoperative Complications; Precipitin Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Sputum; Tracheotomy

Topics: Adult; Aortic Valve; Carbenicillin; Colistin; Corynebacterium diphtheriae; Corynebacterium Infections; Endocarditis, Bacterial; Fascia Lata; Heart Valve Prosthesis; Humans; Male; Penicillin Resistance; Penicillins; Postoperative Complications; Sepsis; Streptomycin

Topics: Ampicillin; Anti-Bacterial Agents; Cephalosporins; Colistin; Colon; Gallbladder; Gentamicins; Humans; Penicillin Resistance; Postoperative Complications; Preoperative Care; Rectum; Stomach

Topics: Cephalothin; Colistin; Enterococcus faecalis; Escherichia coli Infections; Gentamicins; Humans; Kanamycin; Kidney Failure, Chronic; Kidney Function Tests; Male; Novobiocin; Postoperative Complications; Prostatectomy; Pseudomonas aeruginosa; Pseudomonas Infections; Streptococcal Infections; Urinary Tract Infections; Urologic Diseases

Topics: Child; Colistin; Endocarditis, Bacterial; Female; Gentamicins; Heart Failure; Heart Valve Prosthesis; Humans; Polymers; Postoperative Complications; Prognosis; Pseudomonas aeruginosa; Pseudomonas Infections; Silicones; Splenomegaly; Tetralogy of Fallot

Topics: Adult; Aged; Anti-Bacterial Agents; Colistin; Drug Hypersensitivity; Ear Diseases; Epilepsy; Female; Humans; Male; Middle Aged; Muscle Spindles; Nervous System Diseases; Penicillins; Polymyxins; Postoperative Complications

Topics: Adolescent; Adult; Aged; Alkalies; Child; Chloramphenicol; Colistin; Cornea; Corneal Ulcer; Eye Burns; Eye Diseases; Female; Heparin; Humans; Keratitis; Keratitis, Dendritic; Keratoconjunctivitis; Male; Middle Aged; Polymyxins; Postoperative Complications; Retinal Detachment

Topics: Abscess; Colistin; Female; Fistula; Humans; Kidney Diseases; Middle Aged; Postoperative Complications; Salmonella Infections

Topics: Acrylates; Anti-Bacterial Agents; Bacitracin; Chloramphenicol; Chronic Disease; Colistin; Gels; Gentamicins; Humans; Methods; Otitis Media; Postoperative Complications; Tympanoplasty

Topics: Anti-Bacterial Agents; Colistin; Humans; Infection Control; Intestine, Large; Microbial Sensitivity Tests; Neomycin; Peritoneal Cavity; Peritonitis; Postoperative Complications; Procaine; Rectum; Tyrothricin

Topics: Abscess; Adult; Aged; Chloramphenicol; Chondroitin; Colistin; Eye Diseases; Female; Humans; Male; Middle Aged; Ophthalmic Solutions; Postoperative Complications

Topics: Acute Kidney Injury; Appendicitis; Child, Preschool; Colistin; Female; Humans; Kidney Tubules; Paralysis; Postoperative Complications

Topics: Aged; Apnea; Colistin; Drug Synergism; Female; Humans; Male; Middle Aged; Neuromuscular Nondepolarizing Agents; Postoperative Complications

Topics: Adult; Aged; Ampicillin; Anti-Bacterial Agents; Chloramphenicol; Colistin; Cystoscopy; Fever; Humans; Infection Control; Kanamycin; Male; Methods; Middle Aged; Nalidixic Acid; Nitrofurantoin; Penicillin G; Penicillin Resistance; Postoperative Complications; Preoperative Care; Prostatectomy; Streptomycin; Sulfonamides; Tetracycline; Urinary Tract Infections; Urine

Topics: Adult; Bile Ducts, Intrahepatic; Biliary Tract Diseases; Chloramphenicol; Colistin; Female; Humans; Jejunum; Postoperative Complications; Tetracycline

Topics: Colistin; Conjunctiva; Eye Diseases; Humans; Injections; Neomycin; Penicillin G; Polymyxins; Postoperative Complications; Streptomycin

Topics: Anti-Bacterial Agents; Anti-Infective Agents, Local; Bacillus; Bacteria; Bandages; Candida; Colistin; Copper; Escherichia coli; Hexachlorophene; Iodine; Neomycin; Postoperative Complications; Proteus; Pyridines; Silver; Staphylococcus

Topics: Abdomen; Animals; Anti-Bacterial Agents; Appendectomy; Child; Colistin; Dogs; Erythromycin Ethylsuccinate; Female; Humans; Intestinal Obstruction; Penicillins; Postoperative Complications; Rabbits; Streptomycin; Tissue Adhesions

Topics: Adult; Cephalothin; Child; Colistin; Cross Infection; Enterobacter; Enterobacteriaceae Infections; Gentamicins; Germany, West; Humans; Infant, Newborn; Middle Aged; Penicillin Resistance; Penicillins; Postoperative Complications; Sepsis

Topics: Adult; Ampicillin; Colistin; Hematoma, Subdural; Hepatic Encephalopathy; Humans; Lung Abscess; Male; Methicillin; Middle Aged; Pancreatitis; Penicillin Resistance; Postoperative Complications; Pseudomonas Infections

Topics: Apnea; Calcium Chloride; Colistin; Female; Humans; Kidney Calculi; Middle Aged; Paralysis; Postoperative Complications; Preanesthetic Medication; Ureteral Calculi

Topics: Colistin; Diagnosis; Drainage; Drug Therapy; Geriatrics; Humans; Intestinal Obstruction; Laparotomy; Postoperative Complications; Pseudomonas Infections; Radiography; Urinary Bladder Diseases; Urinary Catheterization; Urinary Tract Infections; Urination Disorders

Topics: Adrenal Cortex Hormones; Bacillus; Colistin; Cross Infection; Drug Therapy; gamma-Globulins; Humans; Lung Diseases; Polymyxins; Postoperative Complications; Pseudomonas aeruginosa; Pseudomonas Infections; Resuscitation; Sepsis

Topics: Cholesteatoma; Colistin; Humans; Mastoid; Otitis Media; Postoperative Complications

Topics: Aging; Angiotensins; Bacteremia; Bacteroides; Chloramphenicol; Colistin; Drug Therapy; Enterobacter aerogenes; Escherichia coli Infections; Humans; Iatrogenic Disease; Kanamycin; Metaraminol; Polymyxins; Postoperative Complications; Proteus; Pseudomonas Infections; Sepsis; Sex; Streptomycin; Sympatholytics; Tetracycline; Urinary Tract Infections

Topics: Anti-Bacterial Agents; Bacitracin; Bacterial Infections; Cataract; Cataract Extraction; Cephalothin; Chloramphenicol; Colistin; Drug Therapy; Erythromycin; Eye Diseases; Humans; Kanamycin; Neomycin; Novobiocin; Penicillins; Polymyxins; Postoperative Complications; Sulfadiazine; Tetracycline; Toxicology; Vancomycin

Topics: Anti-Bacterial Agents; Colistin; Female; Genitalia; Genitalia, Female; Gynecology; Humans; Obstetrics; Penicillins; Postoperative Complications; Urinary Tract Infections