colistin has been researched along with Infertility--Male* in 2 studies
2 other study(ies) available for colistin and Infertility--Male
| Article | Year |
|---|---|
Improvement in colistin-induced reproductive damage, apoptosis, and autophagy in testes via reducing oxidative stress by chrysin.
This study aimed to investigate the effect of chrysin on colistin-induced reproductive toxicity. Twenty-eight adult male Sprague-Dawley rats were divided into four groups of seven rats each. Group I received physiological saline for 7 days. Group II received 50 mg/kg/day chrysin for 7 days. Group III received a total dose of 73 mg/kg colistin for 7 days. Group IV received 50 mg/kg/day chrysin by an oral gavage after the colistin treatment. Colistin causes an increase in oxidative stress (OS) in the testis. Chrysin treatment significantly decreased the OS in the chrysin + colistin group compared with the colistin group. The highest caspase-3 and LC3B expression levels were found in the colistin group and these levels were statistically lower in the chrysin + colistin group. Colistin treatment caused a decrease in sperm motility and an increase in sperm abnormality. Chrysin treatment mitigated these side effects significantly. In conclusion, chrysin treatment can be beneficial against colistin-induced reproductive toxicity. Topics: Animals; Anti-Bacterial Agents; Antioxidants; Apoptosis; Autophagy; Caspase 3; Colistin; Dietary Supplements; Epididymis; Flavonoids; Infertility, Male; Injections, Intramuscular; Male; Microtubule-Associated Proteins; Organ Size; Oxidative Stress; Rats, Sprague-Dawley; Sperm Motility; Spermatogenesis; Testis | 2018 |
Influence of antibiotics on spermatogenesis.
Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Chloramphenicol; Colistin; Framycetin; Gentamicins; Infertility, Male; Leucomycins; Male; Nitrofurantoin; Oxytetracycline; Penicillin G; Rats; Spermatogenesis; Trimethoprim | 1974 |