colistin and Cholera

colistin has been researched along with Cholera* in 3 studies

Other Studies

3 other study(ies) available for colistin and Cholera

ArticleYear
Adaptive laboratory evolution of Vibrio cholerae to doxycycline associated with spontaneous mutation.
    International journal of antimicrobial agents, 2020, Volume: 56, Issue:3

    Cholera, caused by the Gram-negative bacterium Vibrio cholerae, remains a serious threat in underdeveloped countries. Although rehydration therapy has been the mainstay of disease management, antibiotics are also being used as an adjunct treatment, resulting in an increase in the circulation of antimicrobial-resistant V. cholerae strains. In the present study, adaptive laboratory evolution, whole-genome sequencing and molecular docking studies were performed to identify putative mutations related to doxycycline resistance in V. cholerae isolates. The V57L mutation in the RpsJ protein was identified to be important in conferring doxycycline resistance. As revealed by molecular docking studies, the mutation was identified to alter the ribosome structure near the doxycycline binding site. Doxycycline stress also induced co-resistance to colistin, a last-resort antibiotic to treat extensively drug-resistant bacteria. This study illustrates for the first time a possible mechanism of doxycycline-selected resistance in V. cholerae as well as doxycycline-selected co-resistance, warranting strict restrictions on the indiscriminate use of antibiotics.

    Topics: Adaptation, Physiological; Anti-Bacterial Agents; Cholera; Colistin; Doxycycline; Drug Resistance; Genome, Bacterial; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Ribosomal Proteins; Vibrio cholerae O1; Whole Genome Sequencing

2020
Vibrio cholerae 0139 diarrhea and acute renal failure in a three-day-old infant.
    The Pediatric infectious disease journal, 1995, Volume: 14, Issue:12

    Topics: Acute Kidney Injury; Ampicillin; Child, Preschool; Cholera; Colistin; Diarrhea; Disease Outbreaks; Drug Therapy, Combination; Feces; Female; Fluid Therapy; Gentamicins; Humans; Infant, Newborn; Male; Thailand; Vibrio cholerae

1995
[SENSITIVITY OF E1 TOR VIBRIO CHOLERAE TO ANTIBIOTICS].
    Nagasaki Igakkai zasshi = Nagasaki medical journal, 1964, Volume: 39

    Topics: Anti-Bacterial Agents; Chloramphenicol; Cholera; Colistin; Humans; Kanamycin; Pharmacology; Tetracycline; Vibrio; Vibrio cholerae

1964