colistin and Bacteroides-Infections

113 patients being treated for acute non-lymphoblastic leukaemia were investigated to determine the effect of suppression of body microbial flora on prevention of infection. They were randomly allocated to a control group or a group which received non-absorbed antibiotics by mouth and topical applications of cutaneous and mucosal antiseptic preparations. The group receiving oral non-absorbed antibiotics had significantly few infections, fewer deaths from infection, fewer pyrexial episodes, and consequently received less systemic antibiotic therapy than the controls.

Topics: Acute Disease; Administration, Oral; Administration, Topical; Adolescent; Adult; Antineoplastic Agents; Bacterial Infections; Bacteroides Infections; Chlorhexidine; Colistin; Drug Combinations; Enterobacteriaceae Infections; Framycetin; Humans; Leukemia; Nystatin; Remission, Spontaneous; Sepsis; Staphylococcal Infections; Staphylococcus aureus; Streptococcal Infections

Topics: Adult; Aged; Bacteroides; Bacteroides Infections; Cephalosporins; Child; Child, Preschool; Colistin; Female; Fusobacterium; Fusobacterium Infections; Germany, West; Humans; Infant; Infant, Newborn; Male; Microbial Sensitivity Tests; Middle Aged; Penicillins; Suppuration

Topics: Adult; Aged; Ampicillin; Bacteroides; Bacteroides Infections; Cephalothin; Chloramphenicol; Colistin; Erythromycin; Female; Humans; Kanamycin; Male; Microbial Sensitivity Tests; Middle Aged; Penicillins; Sepsis; Tetracycline