Page last updated: 2024-08-23

colforsin and Diabetes Mellitus, Type 2

colforsin has been researched along with Diabetes Mellitus, Type 2 in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (22.73)18.2507
2000's8 (36.36)29.6817
2010's7 (31.82)24.3611
2020's2 (9.09)2.80

Authors

AuthorsStudies
Huang, Z; Li, Y; Liu, J; Ma, W; Miranda, KM; Peng, S; Tian, J; Zhang, Y1
Gholami Farashah, MS; Mohammadnejad, D; Naghibi, M; Soleimani Rad, J; Tayefi Nasrabadi, H1
Ameneiro, C; Beiroa, D; Bernardo, G; Bilbao, J; Bravo, SB; Carneiro, C; Cho, JW; Coppari, R; Cuñarro, J; Da Silva Lima, N; Dieguez, C; Dp Chantada-Vazquez, M; Fernandez, U; Fernández-Ramos, D; Ferno, J; Fidalgo, M; Fondevila, MF; Fruhbeck, G; Garcia-Vence, M; Gonzalez-Rellan, MJ; Guallar, D; Herzig, S; Iglesias, C; López, M; Lopitz-Otsoa, F; Martinez-Chantar, ML; Mato, JM; Millet, O; Müller, TD; Nogueiras, R; Novoa, E; Perez-Fernandez, R; Porteiro, B; Rodríguez, A; Sabio, G; Senra, A; Seoane, S; Tovar, S; Varela-Rey, M; Veyrat-Durebex, C; Vidal, A; Woodhoo, A; Yang, WH1
Bernlohr, DA; Billington, CJ; Connett, JC; Foncea, R; Hertzel, AV; Ikramuddin, S; Jahansouz, C; Jensen, M; Josephrajan, A; Kizy, S; Korner, J; Thomas, AJ; Xu, H1
Balaz, M; Belan, V; Kurdiova, T; Maderova, D; Mayer, A; Ukropcova, B; Ukropec, J; Wolfrum, C1
Bajpeyi, S; Covington, JD; Hebert, RC; Masinter, BS; Noland, RC; Ravussin, E; Rustan, AC; Smith, SR1
Gusakova, SV; Kovalev, IV; Mangataeva, OS; Petrova, IV; Suslova, TE; Trubacheva, OA1
Alm, P; Efendic, S; Guenifi, A; Henningsson, R; Jimenez-Feltström, J; Lundquist, I; Mosén, H; Ostenson, CG; Salehi, A1
Cnop, M; Cunha, DA; Eizirik, DL; Gurzov, EN; Igoillo-Esteve, M; Ladrière, L; Lupi, R; Marchetti, P; Ortis, F1
Molkentin, JD; Navedo, MF; Nieves-Cintrón, M; Santana, LF; Takeda, Y1
Albarado, DC; Bajpeyi, S; Church, TS; Conley, KE; Costford, SR; Jubrias, SA; Pasarica, M; Smith, SR; Thomas, SC; Xie, H1
Abdel-Halim, SM; Ahrén, B; Efendic, S; Ljungberg, O; Lukinius, A; Portela-Gomes, GM1
Hatakeyama, H; Kasai, H; Kishimoto, T; Nemoto, T; Takahashi, N1
Mühlbauer, E; Peschke, E; Stumpf, I1
Abdel-Halim, SM; Berggren, PO; Efendić, S; Guenifi, A; Khan, A; Larsson, O; Ostenson, CG1
Arner, P; Dauzats, M; Hellström, L; Langin, D; Reynisdottir, S1
Leclercq-Meyer, V; Malaisse, WJ1
Abdel-Halim, SM; Guenifi, A1
Cerasi, E; Efendic, S; Kaiser, N; Khan, A; Nesher, R; Warwar, N1
Absher, PM; Dunkerley, HA; Jimmo, SL; Maurice, DH; Netherton, SJ; Palmer, D; Raymond, DR; Russell, JC; Sage, EH; Tilley, DG; Vernon, RB1
Houslay, MD; Palmer, TM; Taberner, PV1
Connell, JM; Houslay, MD; Livingstone, C; McGregor, MA; McLellan, AR; Milligan, G; Paterson, KR; Small, M; Wilson, A1

Trials

3 trial(s) available for colforsin and Diabetes Mellitus, Type 2

ArticleYear
Serum FABP4 concentrations decrease after Roux-en-Y gastric bypass but not after intensive medical management.
    Surgery, 2019, Volume: 165, Issue:3

    Topics: Adjuvants, Immunologic; Biomarkers; Colforsin; Critical Care; Diabetes Mellitus, Type 2; Fatty Acid-Binding Proteins; Female; Follow-Up Studies; Gastric Bypass; Humans; Male; Middle Aged; Obesity; Risk Reduction Behavior; Treatment Outcome

2019
Perilipin 3 Differentially Regulates Skeletal Muscle Lipid Oxidation in Active, Sedentary, and Type 2 Diabetic Males.
    The Journal of clinical endocrinology and metabolism, 2015, Volume: 100, Issue:10

    Topics: Adult; Carrier Proteins; Colforsin; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Humans; Lipid Metabolism; Male; Muscle Fibers, Skeletal; Muscle, Skeletal; Palmitic Acid; Perilipin-1; Phosphoproteins; Sedentary Behavior; Young Adult

2015
Skeletal muscle NAMPT is induced by exercise in humans.
    American journal of physiology. Endocrinology and metabolism, 2010, Volume: 298, Issue:1

    Topics: Adenosine Triphosphate; Adult; Cells, Cultured; Colforsin; Cross-Sectional Studies; Cytokines; Diabetes Mellitus, Type 2; Exercise; Exercise Therapy; Heat-Shock Proteins; Humans; Life Style; Middle Aged; Mitochondria; Muscle, Skeletal; Myoblasts; Nicotinamide Phosphoribosyltransferase; Obesity; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Physical Endurance; RNA, Messenger; Signal Transduction; Sports; Transcription Factors; Young Adult

2010

Other Studies

19 other study(ies) available for colforsin and Diabetes Mellitus, Type 2

ArticleYear
Design and synthesis of rosiglitazone-ferulic acid-nitric oxide donor trihybrids for improving glucose tolerance.
    European journal of medicinal chemistry, 2019, Jan-15, Volume: 162

    Topics: Anti-Inflammatory Agents; Antioxidants; Aquaporin 2; Cells, Cultured; Coumaric Acids; Diabetes Mellitus, Type 2; Drug Design; Glucose Intolerance; Humans; Kidney Tubules, Collecting; Metabolic Syndrome; Microsomes, Liver; Nitric Oxide Donors; Rosiglitazone

2019
The effects of metformin and forskolin on sperm quality parameters and sexual hormones in type II diabetic male rats.
    Andrologia, 2022, Volume: 54, Issue:7

    Topics: Animals; bcl-2-Associated X Protein; Blood Glucose; Colforsin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Male; Metformin; Proto-Oncogene Proteins c-bcl-2; Rats; Semen; Sperm Motility; Spermatozoa; Testosterone

2022
O-GlcNAcylated p53 in the liver modulates hepatic glucose production.
    Nature communications, 2021, 08-20, Volume: 12, Issue:1

    Topics: Acetylglucosamine; Animals; Base Sequence; Caloric Restriction; Cell Line; Colforsin; Diabetes Mellitus, Type 2; Epinephrine; Glucagon; Glucocorticoids; Gluconeogenesis; Glucose; Glycosylation; Hepatocytes; Humans; Hydrocortisone; Hyperglycemia; Insulin Resistance; Intracellular Signaling Peptides and Proteins; Liver; Mice, Inbred C57BL; Mice, Knockout; Obesity; Phosphoenolpyruvate Carboxykinase (GTP); Promoter Regions, Genetic; Protein Binding; Protein Stability; Pyruvic Acid; RNA, Messenger; Transcription, Genetic; Tumor Suppressor Protein p53

2021
Exercise-mimicking treatment fails to increase Fndc5 mRNA & irisin secretion in primary human myotubes.
    Peptides, 2014, Volume: 56

    Topics: Cells, Cultured; Colforsin; Diabetes Mellitus, Type 2; Exercise; Fibronectins; Humans; Ionomycin; Muscle Fibers, Skeletal; Muscle, Skeletal; Obesity; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Prediabetic State; RNA, Messenger; Transcription Factors

2014
[THE INFLUENCE OF HYDROGEN SULFIDE ON COLLAGEN-INDUCED AGGREGATION OF HUMAN PLATELETS].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2015, Volume: 101, Issue:10

    Topics: Adult; Blood Platelets; Calcium; Case-Control Studies; Colforsin; Collagen; Cyclic AMP; Diabetes Mellitus, Type 2; Female; Gasotransmitters; Glycosylation; Humans; Hydrogen Sulfide; Male; Middle Aged; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Oxidation-Reduction; Phosphodiesterase Inhibitors; Platelet Aggregation; Platelet Aggregation Inhibitors; Primary Cell Culture; Protein Carbonylation; Sulfides

2015
Impaired glucose-stimulated insulin secretion in the GK rat is associated with abnormalities in islet nitric oxide production.
    Regulatory peptides, 2008, Nov-29, Volume: 151, Issue:1-3

    Topics: Animals; Arginine; Colforsin; Diabetes Mellitus, Type 2; Disease Models, Animal; Enzyme Inhibitors; Female; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Rats; Rats, Wistar

2008
Glucagon-like peptide-1 agonists protect pancreatic beta-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB.
    Diabetes, 2009, Volume: 58, Issue:12

    Topics: Animals; Antigens, Differentiation; Apoptosis; Blotting, Western; Cell Survival; Colforsin; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Endoplasmic Reticulum; Exenatide; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Heat-Shock Proteins; Hypoglycemic Agents; Insulin-Secreting Cells; Lipid Metabolism; Male; Peptides; Polymerase Chain Reaction; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Rats; Rats, Wistar; Receptors, Glucagon; Regulatory Factor X Transcription Factors; RNA Interference; Transcription Factors; Up-Regulation; Venoms

2009
Elevated Ca2+ sparklet activity during acute hyperglycemia and diabetes in cerebral arterial smooth muscle cells.
    American journal of physiology. Cell physiology, 2010, Volume: 298, Issue:2

    Topics: A Kinase Anchor Proteins; Animals; Blood Glucose; Calcium Channels, L-Type; Calcium Signaling; Cerebral Arteries; Colforsin; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Models, Animal; Enzyme Activation; Enzyme Activators; Hyperglycemia; Intracellular Signaling Peptides and Proteins; Membrane Potentials; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Protein Kinase C-alpha; Protein Kinase Inhibitors; Proteins; Rats; Rats, Sprague-Dawley; Signal Transduction; Time Factors; Up-Regulation

2010
PACAP is expressed in secretory granules of insulin and glucagon cells in human and rodent pancreas. Evidence for generation of cAMP compartments uncoupled from hormone release in diabetic islets.
    Regulatory peptides, 2003, May-15, Volume: 113, Issue:1-3

    Topics: Animals; Colforsin; Cyclic AMP; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Glucagon; Glucose; Humans; Immunohistochemistry; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Microscopy, Immunoelectron; Neuropeptides; Pancreas; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Wistar

2003
Rapid glucose sensing by protein kinase A for insulin exocytosis in mouse pancreatic islets.
    The Journal of physiology, 2006, Jan-15, Volume: 570, Issue:Pt 2

    Topics: Animals; Calcium; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, Type 2; Exocytosis; Glucose; Image Cytometry; Insulin; Insulin Secretion; Intracellular Signaling Peptides and Proteins; Islets of Langerhans; Mice; Mice, Inbred ICR; Microscopy, Confocal; Potassium Channels; Thionucleotides

2006
Involvement of the cGMP pathway in mediating the insulin-inhibitory effect of melatonin in pancreatic beta-cells.
    Journal of pineal research, 2008, Volume: 45, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain; Cell Line, Tumor; Colforsin; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Cyclic Nucleotide-Gated Cation Channels; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Glucose; Guanylate Cyclase; Insulin; Insulin Secretion; Insulin-Secreting Cells; Insulinoma; Melatonin; Pineal Gland; Rats; Rats, Wistar; Receptor, Melatonin, MT2; Signal Transduction; Tetrahydronaphthalenes; Tryptamines

2008
Impaired coupling of glucose signal to the exocytotic machinery in diabetic GK rats: a defect ameliorated by cAMP.
    Diabetes, 1996, Volume: 45, Issue:7

    Topics: Animals; Arginine; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Diabetes Mellitus, Type 2; Diazoxide; Exocytosis; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Membrane Potentials; Patch-Clamp Techniques; Rats; Rats, Mutant Strains; Reference Values

1996
Adipocyte lipolysis in normal weight subjects with obesity among first-degree relatives.
    Diabetologia, 1996, Volume: 39, Issue:8

    Topics: Adipocytes; Adrenergic beta-Agonists; Adult; Body Mass Index; Bucladesine; Clonidine; Colforsin; Diabetes Mellitus, Type 2; Dobutamine; Dose-Response Relationship, Drug; Female; Glycerol; Humans; Isoproterenol; Lipolysis; Male; Norepinephrine; Nuclear Family; Obesity; Pedigree; Receptors, Adrenergic, beta; RNA, Messenger; Sterol Esterase; Sympathomimetics; Terbutaline

1996
Modulation of gliquidone action by forskolin in the pancreas of normal and GK rats.
    The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 1

    Topics: Animals; Blood Glucose; Colforsin; Diabetes Mellitus, Type 2; Glucagon; Glucose; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Perfusion; Rats; Rats, Inbred Strains; Rats, Wistar; Reference Values; Sulfonylurea Compounds; Time Factors

1997
Glucose enhances adenylyl cyclase responses in normal but not diabetic GK rat islets.
    Pancreas, 2001, Volume: 22, Issue:1

    Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Glucose; Glycosylation; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats

2001
Defective stimulus-secretion coupling in islets of Psammomys obesus, an animal model for type 2 diabetes.
    Diabetes, 2001, Volume: 50, Issue:2

    Topics: Animals; Colforsin; Diabetes Mellitus, Type 2; Diazoxide; Disease Models, Animal; Disease Susceptibility; Gerbillinae; Glucagon; Glucagon-Like Peptide 1; Glucose; Hyperglycemia; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Isoenzymes; Oxidation-Reduction; Peptide Fragments; Protein Kinase C; Protein Precursors; Rats; Rats, Sprague-Dawley; Reference Values; Signal Transduction; Tetradecanoylphorbol Acetate

2001
Altered phosphodiesterase 3-mediated cAMP hydrolysis contributes to a hypermotile phenotype in obese JCR:LA-cp rat aortic vascular smooth muscle cells: implications for diabetes-associated cardiovascular disease.
    Diabetes, 2002, Volume: 51, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Aorta; Cell Membrane; Cell Movement; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Cytosol; Diabetes Mellitus, Type 2; Hydrolysis; Muscle, Smooth, Vascular; Obesity; Phenotype; Phosphodiesterase Inhibitors; Quinolones; Rats; Rats, Mutant Strains

2002
Alterations in G-protein expression, Gi function and stimulatory receptor-mediated regulation of adipocyte adenylyl cyclase in a model of insulin-resistant diabetes with obesity.
    Cellular signalling, 1992, Volume: 4, Issue:4

    Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Cell Membrane; Cells, Cultured; Colforsin; Diabetes Mellitus; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon; GTP-Binding Proteins; Isoproterenol; Magnesium; Mice; Mice, Inbred CBA; Obesity; Secretin

1992
Altered G-protein expression and adenylate cyclase activity in platelets of non-insulin-dependent diabetic (NIDDM) male subjects.
    Biochimica et biophysica acta, 1991, Feb-22, Volume: 1096, Issue:2

    Topics: Adenylyl Cyclases; Alprostadil; Blood Platelets; Blotting, Western; Cell Membrane; Colforsin; Diabetes Mellitus, Type 2; Enzyme Activation; Epinephrine; GTP-Binding Proteins; Humans; Male; Signal Transduction

1991