Page last updated: 2024-08-23

colforsin and Cardiac Failure

colforsin has been researched along with Cardiac Failure in 52 studies

Research

Studies (52)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (11.54)	18.7374
1990's	24 (46.15)	18.2507
2000's	17 (32.69)	29.6817
2010's	5 (9.62)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bartels, P; Bian, JS; Foo, R; Galupo, MJ; Herzig, S; Hoppe, UC; Hu, Z; Huang, H; Jiang, F; Li, G; Liang, MC; Liao, P; Poh, KK; Ponniah, S; See, K; Soong, TW; Trasti, SL; Wang, J; Wong, YP; Yong, TF; Yu, CY; Yu, D; Zhang, G; Zhang, H	1
Bravo, CA; Levy, D; Oydanich, M; Vatner, DE; Vatner, SF; Yoon, S; Zhang, J	1
Antoons, G; Biesmans, L; Heinzel, FR; Herchuelz, A; Hohendanner, F; Ljubojević, S; MacQuaide, N; Pieske, B; Platzer, D; Sacherer, M; Sedej, S; Sipido, K; Sokolow, S; Wakula, P	1
Barr, LA; Carter, RL; Cheung, JY; Coleman, RC; Feldman, AM; Gao, E; Grisanti, LA; Houser, SR; Koch, WJ; Li, X; Makarewich, CA; Myers, VD; Song, J; Tilley, DG; Troupes, CD; Yu, D; Zhu, W	1
Carlson, M; Jones, JA; Ma, YJ; Rajagopalan, V; Zucker, IH	1
Abraham, TP; Aiba, T; Chakir, K; Daya, SK; Dimaano, VL; Jacques, K; Jaques-Robinson, KM; Kass, DA; Lai, EW; Pacak, K; Tomaselli, GF; Tunin, RS; Xiao, RP; Zhu, WZ	1
Abraham, G; Bohms, B; El-Banayosy, A; Gummert, J; Hasenfuβ, G; Kassner, A; Kolkhof, P; Milting, H; Morshuis, M; Schulte Eistrup, S; Toischer, K	1
Kelly, C; Sawmiller, DR; Tarpey, SB; Thompson, WJ; Townsley, MI	1
Haigney, MC; Hanlon, SU; McCurley, JM; Ruknudin, A; Schulze, DH; Wei, SK	1
Chedid, NG; Díaz G, LE; Masuda, MO; Quintero H, CC; Saraiva, RM	1
Dhalla, NS; Sethi, R	1
Aker, S; Beilfuss, A; Heusch, G; Konietzka, I; Leineweber, K; Martin, C; Rekasi, H; Schulz, R	1
Bers, DM; Curran, J; Hinton, MJ; Ríos, E; Shannon, TR	1
Hata, K; Hirata, K; Kijima, Y; Masai, H; Murata, T; Ohta, S; Shinke, T; Shite, J; Takaoka, H; Yokoyama, M; Yoshikawa, R	1
Minami, K; Ogata, J; Segawa, K	1
Bristow, MR; Ginsburg, R; Minobe, W; Montgomery, W; Strosberg, A	1
Atkins, FL; Bing, OH; Brooks, WW; Conrad, CH; DiMauro, PG; Robinson, KG	1
Mewes, T; Ravens, U	1
Bector, N; Dhalla, NS; Jasmin, G; Nagano, M; Sethi, R; Takeda, N	1
Hammond, HK; Ping, P	1
Alpert, NR; Haeberle, JR; Leavitt, BJ; Martin, BJ; Mulieri, LA	1
Hammond, HK; Helmer, GA; Roth, DA; Urasawa, K	1
Gewitz, MH; Hintze, TH; Mathew, R; Wang, J; Wolin, MS	1
Ghate, AV; Linz, W; Rajagopalan, R; Schoelkens, BA; Subbarayan, P	1
De Mello, WC	1
Matsumori, A; Sasayama, S; Sato, Y	1
Arentzen, CE; Backer, CL; Koumi, S; Sato, R	1
Kozlik-Feldmann, R; Netz, H; Pilz, G; Reber, D; Reithmann, C; Welz, A; Werdan, K	1
Gao, M; Hammond, HK; Insel, PA; Ping, P; Post, S; Tang, R	1
Christensen, G; Holt, E; Lunde, PK; Sejersted, OM; Semb, SO; Tønnessen, T; Wasserstrom, JA	1
Bartel, S; Eschenhagen, T; Haverich, A; Hirt, S; Karczewski, P; Krause, EG; Neumann, J; Schmitz, W; Scholz, H; Stein, B; Thoenes, M	1
Evans, BA; Gu, XH; Kompa, AR; Summers, RJ	1
Bourin, MC; Defer, N; Espinasse, I; Giudicelli, JF; Hanoune, J; Heimburger, M; Iourgenko, V; Mercadier, JJ; Michel, JB; Pussard, E; Richer, C; Samson, F	1
Hosono, M	1
Borst, MM; Herzog, N; Kübler, W; Strasser, RH; Szalai, P	1
Hashimoto, K; Inoue, K; Lurie, KG; Shirai, T; Sugiyama, A	1
Armstrong, J; Dong, E; Hagen, J; Kawai, H; Liang, CS; Mohan, A; Stevens, SY	1
Ito, M; Nakagawa, M; Saikawa, T; Takahashi, N; Teshima, Y; Yasunaga, S; Yonemochi, H	1
Eckhart, A; Gaballa, MA; Goldman, S; Koch, WJ	1
Bokník, P; Knapp, J; Linck, B; Lüss, H; Müller, FU; Neumann, J; Schmitz, W	1
Aomi, S; Chikazawa, G; Endo, M; Hibino, N; Kawai, A; Kihara, S; Koyanagi, H; Kurihara, T; Nishida, H; Uchikawa, S; Uebe, K	1
Bers, DM; Katoh, H; Ziolo, MT	1
Bøkenes, J; Christensen, G; Hoen, IB; Holt, E; Lunde, PK; Sande, JB; Sjaastad, I; Tønnessen, T	1
Hague, NL; Hunneyball, IM; Loh, E; Morgan, JP; Perreault, CL; Sim, MF	1
Del Monte, F; Harding, SE; Jones, SM; Poole-Wilson, PA; Vescovo, G	1
Bouvier, M; Calderone, A; de Champlain, J; Juneau, C; Li, K; Rouleau, JL	1
Feldman, MD; Grossman, W; Gwathmey, JK; Morgan, JP; Phillips, PJ; Schoen, FJ	1
Copelas, L; Feldman, MD; Grossman, W; Gwathmey, JK; Morgan, JP; Phillips, P; Schoen, FJ; Warren, SE	1
Katoh, A; Masuo, M; Sonoki, H; Sugimoto, T; Tomaru, T; Uchida, Y	1
Banerjee, SP; Fan, TH; Kawashima, S; Liang, CS	1
Erne, P; Lipkin, D; Maseri, A	1
Storstein, L	1

Reviews

3 review(s) available for colforsin and Cardiac Failure

Article	Year
[Effects of colforsin daropate hydrochloride on myocardium, smooth muscle and renal function]. Masui. The Japanese journal of anesthesiology, 2007, Volume: 56, Issue:8 Topics: Adenylyl Cyclases; Animals; Cell Proliferation; Colforsin; Cyclic AMP; Glomerular Filtration Rate; Glomerulonephritis, Membranoproliferative; Heart Failure; Humans; Mesangial Cells; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Receptors, Adrenergic, beta-1; Renal Circulation; Signal Transduction	2007
[Cardiovascular effects of colforsin daropate hydrochloride, a novel drug for the treatment of acute heart failure]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1999, Volume: 114, Issue:2 Topics: Adult; Animals; Colforsin; Drug Evaluation, Preclinical; Heart Failure; Hemodynamics; Humans; Male; Myocardial Contraction; Vasodilator Agents	1999
Non-receptor-mediated inotropic drugs. European heart journal, 1988, Volume: 9 Suppl H Topics: Calcium Channel Agonists; Cardiotonic Agents; Colforsin; Heart Failure; Humans; Phosphodiesterase Inhibitors	1988

Trials

1 trial(s) available for colforsin and Cardiac Failure

Article	Year
[Cardiovascular effects of colforsin daropate hydrochloride for acute heart failure after open heart surgery]. Kyobu geka. The Japanese journal of thoracic surgery, 2001, Volume: 54, Issue:12 Topics: Acute Disease; Adenylyl Cyclases; Cardiac Surgical Procedures; Colforsin; Heart Failure; Hemodynamics; Humans; Postoperative Complications; Vasodilator Agents	2001

Other Studies

48 other study(ies) available for colforsin and Cardiac Failure

Article	Year
Exclusion of alternative exon 33 of Ca Proceedings of the National Academy of Sciences of the United States of America, 2017, 05-23, Volume: 114, Issue:21 Topics: Action Potentials; Alternative Splicing; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Colforsin; Electrophysiological Phenomena; Heart Failure; Isoproterenol; Long QT Syndrome; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Myocytes, Cardiac; Nifedipine; Rats; Sequence Deletion; Tachycardia; Ventricular Premature Complexes	2017
A novel adenylyl cyclase type 5 inhibitor that reduces myocardial infarct size even when administered after coronary artery reperfusion. Journal of molecular and cellular cardiology, 2018, Volume: 121 Topics: Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Disease Models, Animal; Enzyme Inhibitors; Heart Failure; Humans; Mice; Myocardial Infarction; Myocardial Reperfusion; Receptors, Adrenergic, beta; Signal Transduction	2018
Intracellular dyssynchrony of diastolic cytosolic [Ca²⁺] decay in ventricular cardiomyocytes in cardiac remodeling and human heart failure. Circulation research, 2013, Aug-16, Volume: 113, Issue:5 Topics: Aniline Compounds; Animals; Calcium Signaling; Calcium-Transporting ATPases; Colforsin; Cytosol; Diastole; Electric Stimulation; Etiocholanolone; Heart Failure; Heart Ventricles; Humans; Hypertrophy; Hypertrophy, Left Ventricular; Indoles; Mice; Mitochondria, Heart; Myocardial Ischemia; Myocytes, Cardiac; Phenyl Ethers; Ruthenium Compounds; Sarcomeres; Sarcoplasmic Reticulum; Sodium-Calcium Exchanger; Sus scrofa; Swine; Ventricular Remodeling	2013
β-adrenergic receptor-mediated cardiac contractility is inhibited via vasopressin type 1A-receptor-dependent signaling. Circulation, 2014, Nov-11, Volume: 130, Issue:20 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Calcium Signaling; Cardiomyopathy, Hypertrophic; Cats; Cell Line, Tumor; Colforsin; Cyclic AMP; G-Protein-Coupled Receptor Kinases; Genes, Reporter; GTP-Binding Protein alpha Subunits, Gq-G11; Heart Failure; HEK293 Cells; Humans; Indoles; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutagenesis, Site-Directed; Myocardial Contraction; Pyrrolidines; Receptors, Adrenergic, beta; Receptors, Vasopressin; Recombinant Fusion Proteins; Rolipram; Second Messenger Systems	2014
Cardiac ErbB-1/ErbB-2 mutant expression in young adult mice leads to cardiac dysfunction. American journal of physiology. Heart and circulatory physiology, 2008, Volume: 295, Issue:2 Topics: Adenylyl Cyclases; Animals; Cardiomyopathy, Dilated; Cardiotonic Agents; Colforsin; Dobutamine; ErbB Receptors; Female; Heart Failure; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Mutation; Myocardial Contraction; Myocytes, Cardiac; Phenotype; Phosphorylation; Receptor, ErbB-2; Signal Transduction; Time Factors; Ventricular Dysfunction, Left	2008
Mechanisms of enhanced beta-adrenergic reserve from cardiac resynchronization therapy. Circulation, 2009, Mar-10, Volume: 119, Issue:9 Topics: Adenylyl Cyclases; Animals; Catecholamines; Colforsin; Dogs; GTP-Binding Protein alpha Subunits, Gi-Go; Heart Failure; Myocardial Contraction; Myocytes, Cardiac; Pacemaker, Artificial; Radioligand Assay; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; RGS Proteins; Sarcomeres; Signal Transduction	2009
Regulation of cyclic adenosine monophosphate release by selective β2-adrenergic receptor stimulation in human terminal failing myocardium before and after ventricular assist device support. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2012, Volume: 31, Issue:10 Topics: Adenylyl Cyclases; Adolescent; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Bisoprolol; Catecholamines; Child; Clenbuterol; Colforsin; Cyclic AMP; Female; Heart Failure; Heart-Assist Devices; Humans; Isoproterenol; Male; Middle Aged; Myocardium; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Young Adult	2012
Phosphodiesterase 3 activity is reduced in dog lung following pacing-induced heart failure. American journal of physiology. Lung cellular and molecular physiology, 2003, Volume: 284, Issue:5 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Capillaries; Capillary Permeability; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Dogs; Heart Failure; Hydrolysis; Lung; Pacemaker, Artificial; Phosphodiesterase Inhibitors; Pulmonary Circulation; Quinolones; Reverse Transcriptase Polymerase Chain Reaction	2003
Protein kinase A hyperphosphorylation increases basal current but decreases beta-adrenergic responsiveness of the sarcolemmal Na+-Ca2+ exchanger in failing pig myocytes. Circulation research, 2003, May-02, Volume: 92, Issue:8 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Animals; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Female; Heart Failure; Isoproterenol; Male; Membrane Potentials; Myocardium; Myocytes, Cardiac; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Receptors, Adrenergic, beta; Sarcolemma; Sodium-Calcium Exchanger; Swine	2003
Impaired beta-adrenergic response and decreased L-type calcium current of hypertrophied left ventricular myocytes in postinfarction heart failure. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2003, Volume: 36, Issue:5 Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Calcium Channels, L-Type; Colforsin; Disease Models, Animal; Dose-Response Relationship, Drug; Electrophysiologic Techniques, Cardiac; Female; Heart Failure; Hypertrophy, Left Ventricular; Isoproterenol; Male; Myocardial Infarction; Myocytes, Cardiac; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Time Factors	2003
Inotropic responses to isoproterenol in congestive heart failure subsequent to myocardial infarction in rats. Journal of cardiac failure, 1995, Volume: 1, Issue:5 Topics: Adenosine Monophosphate; Adrenergic beta-Agonists; Animals; Colforsin; Coronary Vessels; Heart Failure; Isoproterenol; Ligation; Male; Myocardial Contraction; Myocardial Infarction; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta	1995
Inhibition of Na+/H+-exchanger with sabiporide attenuates the downregulation and uncoupling of the myocardial beta-adrenoceptor system in failing rabbit hearts. British journal of pharmacology, 2006, Volume: 148, Issue:2 Topics: Adenylyl Cyclases; Animals; Apoptosis; Colforsin; Down-Regulation; Endomyocardial Fibrosis; Guanidines; Heart; Heart Failure; Heart Ventricles; Myocardium; Norepinephrine; Rabbits; Receptors, Adrenergic, beta; Signal Transduction; Sodium-Hydrogen Exchangers; Time Factors; Ultrasonography; Ventricular Function, Left; Ventricular Remodeling	2006
Beta-adrenergic enhancement of sarcoplasmic reticulum calcium leak in cardiac myocytes is mediated by calcium/calmodulin-dependent protein kinase. Circulation research, 2007, Feb-16, Volume: 100, Issue:3 Topics: Adrenergic beta-Agonists; Animals; Benzylamines; Calcium; Calcium Channels, L-Type; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Diastole; Heart Failure; Isoproterenol; Isoquinolines; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Peptides; Phosphorylation; Protein Processing, Post-Translational; Rabbits; Receptors, Adrenergic, beta; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Signal Transduction; Sulfonamides; Tetracaine	2007
Inhibition of endogenous nitric oxide synthase augments contractile response to adenylyl cyclase stimulation without altering mechanical efficiency in patients with idiopathic dilated cardiomyopathy. Circulation journal : official journal of the Japanese Circulation Society, 2007, Volume: 71, Issue:8 Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aged; Biomechanical Phenomena; Cardiomyopathy, Dilated; Colforsin; Female; Heart Failure; Heart Function Tests; Humans; Male; Middle Aged; Myocardial Contraction; Nitric Oxide Synthase Type III; omega-N-Methylarginine	2007
Pharmacology and inotropic potential of forskolin in the human heart. The Journal of clinical investigation, 1984, Volume: 74, Issue:1 Topics: Adenylyl Cyclases; Animals; Cardiotonic Agents; Cell Membrane; Colforsin; Dihydroalprenolol; Diterpenes; Guinea Pigs; Heart; Heart Failure; Humans; Kinetics; Myocardial Contraction; Myocardium; Receptors, Adrenergic, beta; Species Specificity	1984
Modulation of left and right ventricular beta-adrenergic receptors from spontaneously hypertensive rats with left ventricular hypertrophy and failure. Hypertension (Dallas, Tex. : 1979), 1995, Volume: 26, Issue:1 Topics: Animals; Biochemical Phenomena; Biochemistry; Colforsin; Heart Failure; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; In Vitro Techniques; Isometric Contraction; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta; Stimulation, Chemical	1995
L-type calcium currents of human myocytes from ventricle of non-failing and failing hearts and from atrium. Journal of molecular and cellular cardiology, 1994, Volume: 26, Issue:10 Topics: Adenylyl Cyclases; Adolescent; Adult; Aged; Aged, 80 and over; Biological Transport; Biological Transport, Active; Calcium; Calcium Channels; Calcium Channels, L-Type; Cell Size; Child, Preschool; Colforsin; Cyclic AMP; Down-Regulation; Female; Heart Atria; Heart Failure; Heart Transplantation; Heart Ventricles; Humans; Male; Middle Aged; Muscle Proteins; Myocardium; Patch-Clamp Techniques; Signal Transduction; Tissue Donors	1994
Alterations in G-proteins in congestive heart failure in cardiomyopathic (UM-X7.1) hamsters. Molecular and cellular biochemistry, 1994, Nov-23, Volume: 140, Issue:2 Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cardiomyopathies; Cholera Toxin; Colforsin; Cricetinae; Dihydroalprenolol; Epinephrine; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Heart; Heart Failure; Myocardium; NAD; Norepinephrine; Pertussis Toxin; Sarcolemma; Sodium Fluoride; Virulence Factors, Bordetella	1994
Diverse G protein and beta-adrenergic receptor mRNA expression in normal and failing porcine hearts. The American journal of physiology, 1994, Volume: 267, Issue:5 Pt 2 Topics: Adenylyl Cyclases; Animals; Base Sequence; Cell Membrane; Cloning, Molecular; Colforsin; DNA Primers; Female; Gene Expression; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Heart Atria; Heart Failure; Heart Ventricles; Isoproterenol; Molecular Sequence Data; Myocardium; Polymerase Chain Reaction; Receptors, Adrenergic, beta; Reference Values; RNA, Messenger; Swine; Transcription, Genetic	1994
Myocardial force-frequency defect in mitral regurgitation heart failure is reversed by forskolin. Circulation, 1993, Volume: 88, Issue:6 Topics: Colforsin; Electric Stimulation; Female; Heart Failure; Heart Valve Prosthesis; Humans; In Vitro Techniques; Male; Middle Aged; Mitral Valve; Mitral Valve Insufficiency; Myocardial Contraction; Stroke Volume	1993
Downregulation of cardiac guanosine 5'-triphosphate-binding proteins in right atrium and left ventricle in pacing-induced congestive heart failure. The Journal of clinical investigation, 1993, Volume: 91, Issue:3 Topics: Adenylyl Cyclases; Animals; Blood Pressure; Cell Membrane; Colforsin; Cyclic AMP; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Heart Atria; Heart Failure; Heart Rate; Heart Ventricles; Isoproterenol; Liver; Myocardium; Organ Size; Reference Values; Sodium Fluoride; Swine	1993
Congestive heart failure alters receptor-dependent cAMP-mediated relaxation of canine pulmonary arteries. Circulation, 1993, Volume: 87, Issue:5 Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Dogs; Heart; Heart Failure; Myocardial Contraction; Phosphodiesterase Inhibitors; Pulmonary Artery; Receptors, Cell Surface; Vasodilation	1993
Cardiotonic activity of the water soluble forskolin derivative 8,13-epoxy-6 beta-(piperidinoacetoxy)- 1 alpha, 7 beta, 9 alpha-trihydroxy-labd- 14en-11-one. Arzneimittel-Forschung, 1993, Volume: 43, Issue:3 Topics: Adenosine Diphosphate; Anesthesia; Animals; Cardiotonic Agents; Cats; Colforsin; Cricetinae; Dogs; Electrocardiography; Female; Guinea Pigs; Heart; Heart Failure; Ileum; In Vitro Techniques; Infusions, Intravenous; Isoproterenol; Male; Mesocricetus; Muscle, Smooth; Myocardial Reperfusion Injury; Papillary Muscles; Platelet Aggregation; Propranolol; Rats; Rats, Wistar; Regional Blood Flow	1993
Impaired regulation of cell communication by beta-adrenergic receptor activation in the failing heart. Hypertension (Dallas, Tex. : 1979), 1996, Volume: 27, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cardiomyopathies; Cell Communication; Colforsin; Cricetinae; Electric Conductivity; Gap Junctions; Heart; Heart Failure; Heart Ventricles; In Vitro Techniques; Isoproterenol; Male; Mesocricetus; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Receptors, Adrenergic, beta; Reference Values	1996
Inotropic agent vesnarinone inhibits cytokine production and E-selectin expression in human umbilical vein endothelial cells. Journal of molecular and cellular cardiology, 1995, Volume: 27, Issue:10 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amrinone; Cardiotonic Agents; Cell Adhesion; Cells, Cultured; Colforsin; Cyclic AMP; Cytokines; Depression, Chemical; E-Selectin; Endothelium, Vascular; Gene Expression Regulation; Heart Failure; Hematopoietic Cell Growth Factors; Humans; Intercellular Adhesion Molecule-1; Interleukin-1; Monocytes; Neutropenia; Pyrazines; Quinolines; Tumor Necrosis Factor-alpha; Umbilical Veins; Vascular Cell Adhesion Molecule-1	1995
beta-Adrenergic modulation of the inwardly rectifying potassium channel in isolated human ventricular myocytes. Alteration in channel response to beta-adrenergic stimulation in failing human hearts. The Journal of clinical investigation, 1995, Volume: 96, Issue:6 Topics: Adrenergic beta-Agonists; Adult; Alkaline Phosphatase; Analysis of Variance; Barium; Bucladesine; Cardiomyopathy, Dilated; Cells, Cultured; Colforsin; Coronary Disease; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Female; Heart; Heart Failure; Heart Ventricles; Humans; Isoproterenol; Kinetics; Male; Membrane Potentials; Middle Aged; Myocardium; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Propranolol	1995
A post-receptor defect of adenylyl cyclase in severely failing myocardium from children with congenital heart disease. European journal of pharmacology, 1997, Jul-02, Volume: 330, Issue:1 Topics: Adenosine Diphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adolescent; Cell Membrane; Child; Child, Preschool; Colforsin; Female; GTP-Binding Proteins; Heart Atria; Heart Defects, Congenital; Heart Failure; Humans; Infant, Newborn; Male; Myocardium; Receptors, Adrenergic, beta; Virulence Factors, Bordetella	1997
Increased expression of adenylylcyclase type VI proportionately increases beta-adrenergic receptor-stimulated production of cAMP in neonatal rat cardiac myocytes. Proceedings of the National Academy of Sciences of the United States of America, 1998, Feb-03, Volume: 95, Issue:3 Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Colforsin; Cyclic AMP; Gene Expression Regulation, Enzymologic; GTP-Binding Proteins; Heart Failure; Isoenzymes; Mice; Myocardium; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Signal Transduction	1998
Mechanisms of cardiomyocyte dysfunction in heart failure following myocardial infarction in rats. Journal of molecular and cellular cardiology, 1998, Volume: 30, Issue:8 Topics: Actin Cytoskeleton; Animals; Calcium; Calcium Channels; Calcium-Transporting ATPases; Colforsin; Fura-2; Heart Failure; Heart Ventricles; Hemodynamics; Male; Muscle Contraction; Myocardial Infarction; Myocardium; Patch-Clamp Techniques; Rats; Rats, Wistar; Sarcoplasmic Reticulum; Sodium; Thapsigargin	1998
Dissociation of the effects of forskolin and dibutyryl cAMP on force of contraction and phospholamban phosphorylation in human heart failure. Journal of cardiovascular pharmacology, 1999, Volume: 33, Issue:1 Topics: Adolescent; Adult; Aged; Bucladesine; Calcium-Binding Proteins; Cardiotonic Agents; Colforsin; Female; Heart Failure; Humans; In Vitro Techniques; Male; Middle Aged; Myocardial Contraction; Phosphorylation	1999
Desensitization of cardiac beta-adrenoceptor signaling with heart failure produced by myocardial infarction in the rat. Evidence for the role of Gi but not Gs or phosphorylating proteins. Journal of molecular and cellular cardiology, 1999, Volume: 31, Issue:6 Topics: Adrenergic beta-Agonists; Animals; Arrestins; Autoradiography; beta-Adrenergic Receptor Kinases; beta-Arrestins; Blood Pressure; Calcium; Catechols; Colforsin; Cyclic AMP-Dependent Protein Kinases; G-Protein-Coupled Receptor Kinase 2; Gene Expression Regulation; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Heart Atria; Heart Failure; Heart Ventricles; Isoproterenol; Myocardial Infarction; Organ Size; Pertussis Toxin; Phosphorylation; Propanolamines; Rats; Receptors, Adrenergic, beta; RNA, Messenger; Signal Transduction; Virulence Factors, Bordetella	1999
Decreased type VI adenylyl cyclase mRNA concentration and Mg(2+)-dependent adenylyl cyclase activities and unchanged type V adenylyl cyclase mRNA concentration and Mn(2+)-dependent adenylyl cyclase activities in the left ventricle of rats with myocardial Cardiovascular research, 1999, Volume: 42, Issue:1 Topics: Adenylyl Cyclases; Analysis of Variance; Animals; Blotting, Northern; Colforsin; Enzyme Activation; Gene Expression; Guanosine Triphosphate; Heart Failure; Isoenzymes; Magnesium; Male; Manganese; Microsomes; Myocardial Infarction; Myocardium; Rats; Rats, Wistar; RNA, Messenger; Stimulation, Chemical; Time Factors	1999
Transregulation of adenylyl-cyclase-coupled inhibitory receptors in heart failure enhances anti-adrenergic effects on adult rat cardiomyocytes. Cardiovascular research, 1999, Volume: 44, Issue:1 Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Analysis of Variance; Animals; Calcium Chloride; Carbachol; Cell Size; Cells, Cultured; Colforsin; Dose-Response Relationship, Drug; Electric Stimulation; GTP-Binding Protein alpha Subunits, Gi-Go; Heart; Heart Failure; Isoproterenol; Male; Microscopy, Polarization; Muscarinic Agonists; Phenylisopropyladenosine; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Purinergic P1; Regression Analysis	1999
Measurement of adenylate cyclase activity in the right ventricular endomyocardial biopsy samples from patients with chronic congestive heart failure. Journal of clinical laboratory analysis, 2000, Volume: 14, Issue:2 Topics: Adenosine; Adenylyl Cyclases; Adult; Biopsy; Cell Membrane; Chronic Disease; Colforsin; Female; Heart Failure; Heart Ventricles; Humans; Male; Middle Aged; Myocardium; Norepinephrine; Spectrometry, Fluorescence	2000
Alterations in cardiac adrenergic terminal function and beta-adrenoceptor density in pacing-induced heart failure. American journal of physiology. Heart and circulatory physiology, 2000, Volume: 278, Issue:5 Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Binding Sites; Cardiac Pacing, Artificial; Colforsin; Disease Models, Animal; Down-Regulation; Guanylyl Imidodiphosphate; Heart Failure; Hemodynamics; Myocardium; Nerve Endings; Norepinephrine; Rabbits; Receptors, Adrenergic, beta; Sympathetic Nervous System; Tyrosine 3-Monooxygenase; Ventricular Function, Left	2000
Rapid electrical stimulation of contraction reduces the density of beta-adrenergic receptors and responsiveness of cultured neonatal rat cardiomyocytes. Possible involvement of microtubule disassembly secondary to mechanical stress. Circulation, 2000, Jun-06, Volume: 101, Issue:22 Topics: Acetylcholine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Animals, Newborn; Antineoplastic Agents, Phytogenic; Cells, Cultured; Colforsin; Diacetyl; Dihydroalprenolol; Down-Regulation; Electric Stimulation; Enzyme Inhibitors; Heart Failure; Isoproterenol; Microtubules; Muscle Fibers, Skeletal; Myocardial Contraction; Myocardium; Pacemaker, Artificial; Paclitaxel; Propanolamines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Stress, Mechanical; Tritium; Vasodilator Agents	2000
Vascular beta-adrenergic receptor system is dysfunctional after myocardial infarction. American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Animals; Aorta; Aurora Kinases; Blood Pressure; Carotid Arteries; Colforsin; Coronary Vessels; Cyclic AMP; Cyclic GMP; GTP-Binding Proteins; Heart Failure; In Vitro Techniques; Isoproterenol; Ligation; Muscle, Smooth, Vascular; Myocardial Infarction; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Signal Transduction; Ventricular Pressure	2001
Activation and inactivation of cAMP-response element-mediated gene transcription in cardiac myocytes. Cardiovascular research, 2001, Volume: 52, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Cantharidin; Cardiotonic Agents; Cell Cycle Proteins; Cells, Cultured; Chick Embryo; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Ethanolamines; Gene Expression; Heart Failure; Isoproterenol; Luciferases; Myocardium; Phosphoprotein Phosphatases; Phosphorylation; Plant Proteins; Propane; Stimulation, Chemical; Time Factors; Transcription, Genetic	2001
Expression of inducible nitric oxide synthase depresses beta-adrenergic-stimulated calcium release from the sarcoplasmic reticulum in intact ventricular myocytes. Circulation, 2001, Dec-11, Volume: 104, Issue:24 Topics: Animals; Calcium; Colforsin; Cyclic GMP; Enzyme Inhibitors; Guanidines; Guanylate Cyclase; Heart Failure; Heart Ventricles; Humans; Lipopolysaccharides; Male; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Sarcoplasmic Reticulum	2001
Reduced level of serine(16) phosphorylated phospholamban in the failing rat myocardium: a major contributor to reduced SERCA2 activity. Cardiovascular research, 2002, Feb-01, Volume: 53, Issue:2 Topics: Adrenergic beta-Agonists; Animals; Calcium; Calcium-Binding Proteins; Calcium-Transporting ATPases; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Heart Failure; Homeostasis; Immunoblotting; Intracellular Fluid; Isoproterenol; Isoquinolines; Male; Myocardial Infarction; Myocardium; Phosphorylation; Rats; Rats, Wistar; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sulfonamides	2002
Differential inotropic effects of flosequinan in ventricular muscle from normal ferrets versus patients with end-stage heart failure. British journal of pharmacology, 1992, Volume: 106, Issue:3 Topics: Animals; Calcium; Colforsin; Dose-Response Relationship, Drug; Ferrets; Heart Failure; Heart Ventricles; Humans; In Vitro Techniques; Male; Milrinone; Myocardial Contraction; Pyridones; Quinolines; Quinolones; Stimulation, Chemical; Vasodilator Agents	1992
Reduced contractile responses to forskolin and a cyclic AMP analogue in myocytes from failing human ventricle. European journal of pharmacology, 1992, Nov-13, Volume: 223, Issue:1 Topics: Adult; Aging; Bucladesine; Calcium; Colforsin; Diuretics; Female; Heart Failure; Heart Ventricles; Humans; In Vitro Techniques; Isoproterenol; Male; Middle Aged; Myocardial Contraction	1992
Dysfunction of the beta- and alpha-adrenergic systems in a model of congestive heart failure. The pacing-overdrive dog. Circulation research, 1991, Volume: 69, Issue:2 Topics: Adenylyl Cyclases; Animals; Cardiac Pacing, Artificial; Colforsin; Dogs; Guanylyl Imidodiphosphate; Heart Failure; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Norepinephrine; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sodium-Potassium-Exchanging ATPase	1991
Post-extrasystolic potentiation and the force-frequency relationship: differential augmentation of myocardial contractility in working myocardium from patients with end-stage heart failure. Journal of molecular and cellular cardiology, 1990, Volume: 22, Issue:1 Topics: Assisted Circulation; Calcium; Cardiac Complexes, Premature; Colforsin; Cyclic AMP; Electric Stimulation; Heart Failure; Humans; In Vitro Techniques; Myocardial Contraction	1990
Deficient production of cyclic AMP: pharmacologic evidence of an important cause of contractile dysfunction in patients with end-stage heart failure. Circulation, 1987, Volume: 75, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; Caffeine; Calcium; Cardiotonic Agents; Colforsin; Cyclic AMP; Heart Failure; Humans; Isoproterenol; Milrinone; Myocardial Contraction; Myocardium; Pyridones; Stimulation, Chemical; Strophanthidin	1987
[Effects of forskolin on canine congestive heart failure]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1986, Volume: 88, Issue:5 Topics: Animals; Blood Pressure; Colforsin; Dextrans; Disease Models, Animal; Dogs; Heart Failure; Heart Rate; Methoxamine; Myocardial Contraction; Peptide Hydrolases; Vascular Resistance	1986
Alterations in cardiac beta-adrenoceptor responsiveness and adenylate cyclase system by congestive heart failure in dogs. European journal of pharmacology, 1987, Aug-11, Volume: 140, Issue:2 Topics: 5'-Nucleotidase; Adenylyl Cyclases; Animals; Chlorides; Colforsin; Dihydroalprenolol; Dobutamine; Dogs; Guanylyl Imidodiphosphate; Heart Failure; Hemodynamics; In Vitro Techniques; Isoproterenol; Kinetics; Manganese; Manganese Compounds; Myocardium; Norepinephrine; Nucleotidases; Receptors, Adrenergic, beta	1987
Impaired beta-adrenergic receptor and normal postreceptor responsiveness in congestive heart failure. The American journal of cardiology, 1988, May-01, Volume: 61, Issue:13 Topics: Adenylyl Cyclases; Blood Pressure; Colforsin; Dose-Response Relationship, Drug; Heart Failure; Heart Rate; Humans; Injections, Intravenous; Isoproterenol; Male; Myocardial Contraction; Receptors, Adrenergic, beta; Regression Analysis	1988