colforsin has been researched along with Cancer of Pancreas in 70 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (10.00) | 18.7374 |
| 1990's | 38 (54.29) | 18.2507 |
| 2000's | 20 (28.57) | 29.6817 |
| 2010's | 5 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Burdyga, A; Conant, A; Costello, E; Haynes, L; Jalink, K; Neoptolemos, J; Sutton, R; Tepikin, A; Zhang, J | 1 |
| Dwinell, MB; Hauser, AD; Roy, I; Williams, CL; Wilson, JM; Zimmerman, NP | 1 |
| Akiyama, S; Aoki, T; Araki, O; Murakami, M; Ogiwara, T; Tsunekawa, K | 1 |
| Dains-McGahee, C; Friedman, EM; Graves, SH; Hassan, H; Quinn, SN; Sabbatini, ME; Witkowski, P | 1 |
| Adler, G; Aleksic, T; Lorenz, R; Wagner, M; Weber, CK | 1 |
| Guimaraes, AR; Rakhlin, E; Thayer, SP; Weissleder, R | 1 |
| Albrecht, E; Bazwinsky-Wutschke, I; Mühlbauer, E; Peschke, E; Wolgast, S | 1 |
| Chankiewitz, E; Csernus, VJ; Mühlbauer, E; Musshoff, U; Peschke, D; Peschke, E | 1 |
| Andon, NL; Bilakovics, JM; Ghosh, SS; Hanley, MR; Lowe, C; Pittner, R; Taylor, SW | 1 |
| Aust, S; Brucker, B; Graf, J; Klimpfinger, M; Thalhammer, T | 1 |
| Pozzan, T; Ullrich, S; Wollheim, CB | 1 |
| Cronin, MJ; Evans, WS; Hewlett, EL; Rogol, AD; Thorner, MO | 1 |
| Dunn, KW; Gelman, DL; McGraw, TE; Park, J; Semrad, CE; Shevell, T | 1 |
| de Mazancourt, P; Goldsmith, PK; Weinstein, LS | 1 |
| Banks, TC; Crystal, RG; Danel, C; Rosenfeld, MA; Rosenfeld, SJ | 1 |
| McDermott, AM; Sharp, GW | 1 |
| Bara, J; Claret, S; Fanjul, M; Forgue-Lafitte, ME; Hollande, E | 1 |
| Bokvist, K; Dissing, S; Frøkjaer-Jensen, J; Gromada, J; Renström, E; Rorsman, P; Wulff, BS | 1 |
| Cai, RZ; Ertl, T; Groot, K; Horvath, J; Qin, Y; Schally, AV | 1 |
| Kojima, I; Miyazaki, J; Ogata, E; Sekine, N; Yamashita, N | 1 |
| Habener, JF; Holz, GG; Leech, CA | 1 |
| Fehmann, HC; Göke, B; Strowski, M | 1 |
| Farshori, PQ; Goode, D | 1 |
| Bertherat, J; Epelbaum, J; Li, JY; Rauch, C; Sassolas, G; Schaison, G; Turpin, G | 1 |
| Becker, TC; BeltrandelRio, H; Cassidy, LE; Clark, S; Ferber, S; Hughes, SD; Johnson, JH; Newgard, CB; Noel, RJ | 1 |
| Demura, H; Emoto, N; Isozaki, O; Murakami, H; Ohmura, E; Onoda, N; Robins, RK; Shizume, K; Tsushima, T; Wakai, K | 1 |
| Brunner, HR; Grouzmann, E; Nicod, P; Thompson, N; Waeber, B; Waeber, G | 1 |
| al-Nakkash, L; Argent, BE; Lingard, JM; Simmons, NL | 1 |
| Figarella, C; Merten, M; Montserrat, C | 1 |
| Fehmann, HC; Göke, B; Jiang, J; Pitt, D; Schweinfurth, J | 1 |
| Cobb, MH; Khoo, S | 1 |
| Cobb, MH; Dang, A; Do, V; Khoo, S; Schaefer, EM; Witt, S; Xu, S; Zhen, E | 1 |
| Bhatt, H; Easom, RA; Krueger, KA; Landt, M | 1 |
| Bokník, P; Knapp, J; Müller, FU; Neumann, J; Oetjen, E; Scheld, HH; Schmitz, W; Vahlensieck, U | 1 |
| Farrelly, ER; Hirakawa, K; Ho, JJ; Kim, YS; Sowa, M; Yamashita, Y | 1 |
| Demuth, HU; Ehses, J; Hinke, SA; Kerridge, P; McIntosh, CH; Pauly, RP; Pederson, RA | 1 |
| Aust, G; Nguyen, TB; Scherbaum, WA; Seissler, J; Steinbrenner, H | 1 |
| Farrelly, ER; Ho, JJ; Hong, J; Kim, YS; Pan, P | 1 |
| Bohrer, A; Hsu, FF; Ma, Z; Ramanadham, S; Turk, J; Wohltmann, M | 1 |
| Hescheler, J; Lenka, N; Su, J; Ullrich, S; Yu, H | 1 |
| Armatis, P; Csernus, B; Groot, K; Halmos, G; Plonowski, A; Rekasi, Z; Schally, AV; Varga, JL | 1 |
| Boucher, MJ; Duchesne, C; Lainé, J; Morisset, J; Rivard, N | 1 |
| Barabás, K; Burghardt, B; Coy, DH; Flautner, L; Gress, TM; Oláh, A; Rácz, G; Varga, G; Wenger, C | 1 |
| Bloch, K; Vardi, P | 1 |
| Ding, WQ; Holicky, E; Miller, LJ | 1 |
| Chepurny, OG; Holz, GG; Kang, G | 1 |
| Ma, Z; Ramanadham, S; Turk, J; Zhang, S | 1 |
| Crawley, S; Farrelly, ER; Ho, JJ; Kim, YS; Pan, PL | 1 |
| Ahnert-Hilger, G; Faiss, S; Grabowski, P; Hoegerle, S; Höpfner, M; Jockers-Scherübl, M; Lemmer, K; Riecken, EO; Scherübl, H; Zeitz, M | 1 |
| Abe, S; Ishizuka, J; Murakami, M; Satoh, Y; Shintani, S; Suzuki, K; Suzuki, S; Thompson, JC; Toyota, T | 1 |
| Ku, JC; Liu, MY; Wu, MC | 1 |
| Funakoshi, A; Kitayama, N; Matsuoka, Y; Tateishi, K | 1 |
| Asfari, M; Halban, PA; Janjic, D; Li, G; Meda, P; Wollheim, CB | 1 |
| Root, KV; Schreiber, JH; Van Dyke, RW; Wilson, JM | 1 |
| Berta, G; Bradbury, NA; Bridges, RJ; Jilling, T; Kirk, KL; Sorscher, EJ | 1 |
| Fehmann, HC; Habener, JF | 1 |
| Bockaert, J; Carrette, J; Fehrentsz, JA; Hillaire-Buys, D; Landry, Y; Mousli, M; Rouot, B | 1 |
| Beinfeld, MC | 1 |
| Cooper, CW; Ishizuka, J; Murakami, M; Nickols, GA; Sumi, S; Thompson, JC; Townsend, CM | 1 |
| D'Ambra, R; Efrat, S; Fleischer, N; Starr, RG; Surana, M | 1 |
| Chiba, T; Fujita, T; Kadowaki, S; Morishita, T; Nakamura, A; Yamaguchi, A; Yamatani, T | 1 |
| Efrat, S; Fleischer, N; Surana, M | 1 |
| Agarwal, KC; Tzanakakis, GN; Veronikis, DK; Vezeridis, MP | 1 |
| Akatsu, T; Kinoshita, T; Kosano, H; Kugai, N; Nagata, N; Takatani, O; Wada, S; Yasutomo, Y | 1 |
| Agarwal, KC; Tzanakakis, GN; Vezeridis, MP | 1 |
| Danoff, A; Fleischer, N; Pasmantier, R; Schubart, UK | 1 |
| Chiba, T; Fujita, T; Inui, T; Kadowaki, S; Saito, Y; Yamaguchi, A; Yamatani, T | 1 |
| Estival, A; Lherisson, C; Pradayrol, L; Vaysse, N | 1 |
| Gold, G; Grodsky, GM; Wieland, FT | 1 |
| Schonbrunn, A; Sullivan, SJ | 1 |
70 other study(ies) available for colforsin and Cancer of Pancreas
| Article | Year |
|---|---|
cAMP inhibits migration, ruffling and paxillin accumulation in focal adhesions of pancreatic ductal adenocarcinoma cells: effects of PKA and EPAC.
Topics: 1-Methyl-3-isobutylxanthine; Adenocarcinoma; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Movement; Cell Surface Extensions; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Focal Adhesions; Guanine Nucleotide Exchange Factors; Humans; Neoplasm Invasiveness; Pancreatic Neoplasms; Paxillin; Protein Transport | 2013 |
Cyclic AMP regulates the migration and invasion potential of human pancreatic cancer cells.
Topics: 1-Methyl-3-isobutylxanthine; Amides; Apoptosis; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Deoxycytidine; Enzyme Inhibitors; Gemcitabine; Humans; Neoplasm Invasiveness; Pancreatic Neoplasms; Phosphodiesterase Inhibitors; Pyridines; Quinolones; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; rhoC GTP-Binding Protein; Vasodilator Agents | 2015 |
Glucagon-like peptide-1 stimulates type 3 iodothyronine deiodinase expression in a mouse insulinoma cell line.
Topics: Animals; Cell Line, Tumor; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Exenatide; Gene Expression Regulation, Neoplastic; Glucagon-Like Peptide 1; Insulin-Secreting Cells; Insulinoma; Iodide Peroxidase; Mice; Pancreatic Neoplasms; Peptides; RNA, Messenger; Signal Transduction; Triiodothyronine; Triiodothyronine, Reverse; Venoms | 2014 |
Adenylyl cyclase 3/adenylyl cyclase-associated protein 1 (CAP1) complex mediates the anti-migratory effect of forskolin in pancreatic cancer cells.
Topics: Adenylyl Cyclases; Adult; Aged; Animals; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cytoskeletal Proteins; Enzyme Activators; Female; Humans; Male; Mice; Middle Aged; Pancreatic Neoplasms; RNA Interference; RNA, Small Interfering; Up-Regulation | 2017 |
The cAMP/Epac1/Rap1 pathway in pancreatic carcinoma.
Topics: Adenylyl Cyclases; Cell Line, Tumor; Cell Proliferation; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activators; Guanine Nucleotide Exchange Factors; Humans; Pancreatic Neoplasms; RNA Interference; Shelterin Complex; Signal Transduction; Telomere-Binding Proteins; Time Factors | 2008 |
Magnetic resonance imaging monitors physiological changes with antihedgehog therapy in pancreatic adenocarcinoma xenograft model.
Topics: Angiogenesis Inhibitors; Animals; Antibodies; Carcinoma, Pancreatic Ductal; Cell Proliferation; Colforsin; Contrast Media; Ferrosoferric Oxide; Hedgehog Proteins; Humans; Injections, Intravenous; Magnetic Resonance Imaging; Mice; Mice, Nude; Nanoparticles; Neovascularization, Pathologic; Pancreatic Neoplasms; Signal Transduction; Veratrum Alkaloids; Xenograft Model Antitumor Assays | 2008 |
Phosphorylation of cyclic AMP-response element-binding protein (CREB) is influenced by melatonin treatment in pancreatic rat insulinoma β-cells (INS-1).
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Line, Tumor; Colforsin; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; Fluorescent Antibody Technique; Humans; Insulin-Secreting Cells; Insulinoma; Melatonin; Microscopy, Confocal; Pancreatic Neoplasms; Phosphorylation; Rats; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Signal Transduction; Tetrahydronaphthalenes; Time Factors; Transfection; Tryptamines | 2012 |
Receptor (MT(1)) mediated influence of melatonin on cAMP concentration and insulin secretion of rat insulinoma cells INS-1.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Biological Transport; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Melatonin; Pancreatic Neoplasms; Phosphodiesterase Inhibitors; Polymerase Chain Reaction; Probenecid; Rats; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Signal Transduction; Tryptamines; Tumor Cells, Cultured | 2002 |
Efficient high-throughput discovery of large peptidic hormones and biomarkers.
Topics: Amino Acid Sequence; Animals; Biomarkers, Tumor; Cell Line, Tumor; Colforsin; Computer Simulation; Culture Media, Conditioned; Drug Evaluation, Preclinical; Hormones; Insulinoma; Molecular Sequence Data; Pancreatic Neoplasms; Peptides; Proteomics; Rats | 2006 |
Melatonin modulates acid/base transport in human pancreatic carcinoma cells.
Topics: Acids; Antiporters; Bicarbonates; Biological Transport; Cell Line, Tumor; Colforsin; Cyclic AMP; Gene Expression; Humans; Hydrogen-Ion Concentration; Melatonin; Models, Biological; Pancreatic Neoplasms; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Symporters | 2006 |
Glyceraldehyde, but not cyclic AMP-stimulated insulin release is preceded by a rise in cytosolic free Ca2+.
Topics: Aminoquinolines; Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Diterpenes; Fluorescent Dyes; Glyceraldehyde; Insulin; Insulinoma; Membrane Potentials; Pancreatic Neoplasms | 1984 |
Human pancreatic tumor growth hormone (GH) - releasing factor and cyclic adenosine 3',5'- monophosphate evoke GH release from anterior pituitary cells: the effects of pertussis toxin, cholera toxin, forskolin, and cycloheximide.
Topics: Animals; Antihypertensive Agents; Bacterial Toxins; Cholera Toxin; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Cycloheximide; Diterpenes; Growth Hormone; Humans; In Vitro Techniques; Kinetics; Male; Pancreatic Neoplasms; Pertussis Toxin; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Somatostatin; Virulence Factors, Bordetella | 1984 |
Regulation of endocytic trafficking and acidification are independent of the cystic fibrosis transmembrane regulator.
Topics: Adenocarcinoma; Cell Line; Cell Membrane; Chloride Channels; Chlorides; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Endocytosis; Humans; Hydrogen-Ion Concentration; Iron; Kinetics; Membrane Proteins; Microscopy, Fluorescence; Pancreatic Neoplasms; Receptors, Transferrin; Transfection; Transferrin; Tumor Cells, Cultured; Wheat Germ Agglutinins | 1994 |
Inhibition of adenylate cyclase activity by galanin in rat insulinoma cells is mediated by the G-protein Gi3.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Amino Acid Sequence; Animals; Antibody Specificity; Base Sequence; Colforsin; Electrophoresis, Polyacrylamide Gel; Fluorescein-5-isothiocyanate; Fluorescent Antibody Technique; Galanin; GTP-Binding Proteins; Insulin; Insulin Secretion; Insulinoma; Molecular Sequence Data; Neuropeptides; Oligonucleotides, Antisense; Pancreatic Neoplasms; Peptides; Pertussis Toxin; Phosphates; Protein Biosynthesis; Rats; Receptors, Galanin; Receptors, Gastrointestinal Hormone; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1994 |
Increasing expression of the normal human CFTR cDNA in cystic fibrosis epithelial cells results in a progressive increase in the level of CFTR protein expression, but a limit on the level of cAMP-stimulated chloride secretion.
Topics: Adenocarcinoma; Adenoviruses, Human; Animals; Chlorides; Colforsin; Colonic Neoplasms; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; DNA, Complementary; Epithelium; Genetic Vectors; Humans; Mammary Neoplasms, Experimental; Membrane Proteins; Mice; Pancreatic Neoplasms; Recombinant Fusion Proteins; Secretory Rate; Tumor Cells, Cultured | 1994 |
Noradrenaline induces supersensitivity of adenylyl cyclase in NG108-15 and HT29-18 cells but not in the beta-cell RINm5F.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Gastric Inhibitory Polypeptide; Glioma; Humans; Hybrid Cells; Insulinoma; Kinetics; Neuroblastoma; Norepinephrine; Pancreatic Neoplasms; Tumor Cells, Cultured | 1995 |
Effects of VIP on the regulation of mucin secretion in cultured human pancreatic cancer cells (Capan-1).
Topics: Cell Polarity; Colforsin; Cytoplasm; Cytoplasmic Granules; Enzyme-Linked Immunosorbent Assay; Exocytosis; Humans; Immunohistochemistry; Microscopy, Electron; Mucins; Neuropeptides; Pancreatic Neoplasms; Pituitary Adenylate Cyclase-Activating Polypeptide; Secretin; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1995 |
Glucagon-like peptide I increases cytoplasmic calcium in insulin-secreting beta TC3-cells by enhancement of intracellular calcium mobilization.
Topics: Animals; Calcium; Calcium Channels; Cell Line; Colforsin; Cyclic AMP; Cytoplasm; Dose-Response Relationship, Drug; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Inositol Phosphates; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Kinetics; Mice; Mice, Transgenic; Pancreatic Neoplasms; Peptide Fragments; Ryanodine; Time Factors; Tumor Cells, Cultured | 1995 |
Somatostatin analog RC-160 inhibits growth of CFPAC-1 human pancreatic cancer cells in vitro and intracellular production of cyclic adenosine monophosphate.
Topics: Amino Acid Sequence; Antineoplastic Agents; Binding, Competitive; Carcinoma; Cell Division; Colforsin; Cyclic AMP; Depression, Chemical; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Sequence Data; Neoplasm Proteins; Octreotide; Pancreatic Neoplasms; Receptors, Somatostatin; Signal Transduction; Somatostatin; Tumor Cells, Cultured | 1995 |
Bimodal effect of transforming growth factor-beta on insulin secretion in MIN6 cells.
Topics: Animals; Colforsin; Dose-Response Relationship, Drug; Glucose; Humans; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Mice; Pancreatic Neoplasms; Tolbutamide; Transforming Growth Factor beta; Tumor Cells, Cultured | 1994 |
Pituitary adenylate cyclase-activating polypeptide induces the voltage-independent activation of inward membrane currents and elevation of intracellular calcium in HIT-T15 insulinoma cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Calcium; Calcium Channels; Colforsin; Electric Conductivity; Fura-2; Insulin; Insulin Secretion; Insulinoma; Lanthanum; Manganese; Membrane Potentials; Neuropeptides; Pancreatic Neoplasms; Pituitary Adenylate Cyclase-Activating Polypeptide; Sodium Channels; Spectrometry, Fluorescence; Tumor Cells, Cultured | 1995 |
Interaction of glucagon-like peptide-I (7-37) and somatostatin-14 on signal transduction and proinsulin gene expression in beta TC-1 cells.
Topics: Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Drug Interactions; Gene Expression; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Insulinoma; Mice; Pancreatic Neoplasms; Peptides; Proinsulin; Receptors, Cell Surface; Receptors, Glucagon; Signal Transduction; Somatostatin; Tumor Cells, Cultured | 1994 |
Effects of the microtubule depolymerizing and stabilizing agents Nocodazole and taxol on glucose-induced insulin secretion from hamster islet tumor (HIT) cells.
Topics: Adenoma, Islet Cell; Animals; Colforsin; Cricetinae; Fluorescent Antibody Technique; Glucose; Insulin; Insulin Secretion; Microscopy, Electron; Microtubules; Nocodazole; Paclitaxel; Pancreatic Neoplasms; Tumor Cells, Cultured | 1994 |
Presence of somatostatin receptors negatively coupled to adenylate cyclase in ectopic growth hormone-releasing hormone- and alpha-subunit-secreting tumors from acromegalic patients responsive to octreotide.
Topics: Acromegaly; Adenylyl Cyclases; Adult; Carcinoid Tumor; Colforsin; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Immunohistochemistry; Insulinoma; Male; Multiple Endocrine Neoplasia Type 1; Octreotide; Pancreatic Neoplasms; Receptors, Somatostatin | 1994 |
GLUT-2 gene transfer into insulinoma cells confers both low and high affinity glucose-stimulated insulin release. Relationship to glucokinase activity.
Topics: 3-O-Methylglucose; Adenoviridae; Animals; Biological Transport; Cell Line; Colforsin; Gene Expression; Genetic Vectors; Glucokinase; Glucose; Glucose Transporter Type 2; Hexokinase; Humans; Insulin; Insulin Secretion; Insulinoma; Kinetics; Methylglucosides; Monosaccharide Transport Proteins; Pancreatic Neoplasms; Rats; RNA, Messenger; Transfection; Tumor Cells, Cultured | 1994 |
Inhibition of human pancreatic cancer cell (MIA PaCa-2) growth by cholera toxin and 8-chloro-cAMP in vitro.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cholera Toxin; Colforsin; Cyclic AMP; Drug Synergism; Epidermal Growth Factor; Humans; Immunologic Factors; Insulin-Like Growth Factor I; Pancreatic Neoplasms; Proto-Oncogene Proteins p21(ras); Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Neuropeptide Y expression and regulation in a differentiated rat insulin-secreting cell line.
Topics: Adenylyl Cyclases; Animals; Cell Differentiation; Clonidine; Colforsin; Cyclic AMP; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Neoplastic; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Insulin Secretion; Insulinoma; Neuropeptide Y; Pancreatic Neoplasms; Peptide Fragments; Protein Kinase C; Rats; Receptors, Neuropeptide Y; Tumor Cells, Cultured | 1993 |
Adenylate cyclase activity in human pancreatic adenocarcinoma cell lines.
Topics: Adenocarcinoma; Adenylyl Cyclases; Adrenergic beta-Agonists; Bicarbonates; Colforsin; Dopamine; Humans; Neuropeptides; Pancreatic Neoplasms; Receptors, Cell Surface; Tumor Cells, Cultured | 1996 |
Defective ATP-dependent mucin secretion by cystic fibrosis pancreatic epithelial cells.
Topics: Adenocarcinoma; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adult; Antigens; Calcium; Carbachol; Cell Line; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelium; Humans; Immunoassay; Mucins; Pancreatic Neoplasms; Receptors, Purinergic P2; Transfection; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1996 |
Ligand-induced regulation of glucagon-like peptide-I receptor function and expression in insulin-secreting beta cells.
Topics: Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Enzyme Activation; Gene Expression; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Guanosine 5'-O-(3-Thiotriphosphate); Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Pancreatic Neoplasms; Peptide Fragments; Protein Precursors; Protein Synthesis Inhibitors; Rats; Receptors, Glucagon; RNA, Messenger; Tumor Cells, Cultured | 1996 |
Activation of mitogen-activating protein kinase by glucose is not required for insulin secretion.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Colforsin; Deoxyglucose; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Glucose; Insulin; Insulin Secretion; Insulinoma; JNK Mitogen-Activated Protein Kinases; Kinetics; Mannoheptulose; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Pancreatic Neoplasms; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; Tolbutamide; Tumor Cells, Cultured | 1997 |
Differential regulation of mitogen-activated protein/ERK kinase (MEK)1 and MEK2 and activation by a Ras-independent mechanism.
Topics: 3T3 Cells; Aluminum Compounds; Animals; Antibodies, Monoclonal; Astrocytes; Carbachol; Cell Line; CHO Cells; Colforsin; Cricetinae; Cricetulus; Embryo, Mammalian; Enzyme Activation; Enzyme Induction; Fluorides; Gene Expression Regulation, Enzymologic; Glucose; GTP-Binding Proteins; Insulin; Insulin Secretion; Insulinoma; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mice; Mitogen-Activated Protein Kinase Kinases; Pancreatic Neoplasms; PC12 Cells; Pheochromocytoma; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; Receptors, Cell Surface; Recombinant Fusion Proteins; Signal Transduction; Transfection; Tumor Cells, Cultured | 1997 |
Calcium-stimulated phosphorylation of MAP-2 in pancreatic betaTC3-cells is mediated by Ca2+/calmodulin-dependent kinase II.
Topics: Adenylyl Cyclases; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Insulinoma; Islets of Langerhans; Isoquinolines; Kinetics; Microtubule-Associated Proteins; Pancreatic Neoplasms; Peptide Mapping; Phosphopeptides; Phosphorylation; Rats; Sulfonamides; Tumor Cells, Cultured | 1997 |
Identification and expression of a novel isoform of cAMP response element modulator in the human heart.
Topics: Animals; Cloning, Molecular; Colforsin; Cricetinae; Cyclic AMP Response Element Modulator; Dimethyl Sulfoxide; DNA-Binding Proteins; Escherichia coli; Humans; Insulinoma; Myocardium; Pancreatic Neoplasms; Polymerase Chain Reaction; Recombinant Proteins; Repressor Proteins; RNA, Messenger; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1998 |
Forskolin and phorbol ester have opposite effects on the expression of mucin-associated sialyl-Lewis(a) in pancreatic cancer cells.
Topics: Blotting, Western; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dactinomycin; Humans; Mucin-1; Oligosaccharides; Pancreatic Neoplasms; Phorbol Esters; Protein Kinase C; RNA, Messenger; Sialyl Lewis X Antigen; Tumor Cells, Cultured | 2000 |
Role of glucose in chronic desensitization of isolated rat islets and mouse insulinoma (betaTC-3) cells to glucose-dependent insulinotropic polypeptide.
Topics: Analysis of Variance; Animals; Colforsin; Cyclic AMP; Gastric Inhibitory Polypeptide; Glucose; Insulin; Insulinoma; Islets of Langerhans; Male; Mice; Pancreatic Neoplasms; Perfusion; Rats; Rats, Wistar; Signal Transduction; Tumor Cells, Cultured | 2000 |
Regulation of the diabetes-associated autoantigen IA-2 in INS-1 pancreatic beta-cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Autoantigens; Colforsin; Cyclic AMP; Gene Expression Regulation; Glucagon; Glucose; Insulinoma; Islets of Langerhans; Kinetics; Membrane Proteins; Pancreatic Neoplasms; Protein Kinase C; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Rats; Receptor-Like Protein Tyrosine Phosphatases, Class 8; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Somatostatin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2000 |
Forskolin increases the expression of the pancreatic tumor antigen, Nd2, and uptake of Nd2 antibody.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Antibodies, Neoplasm; Antigens, Neoplasm; Carbohydrate Conformation; Carcinoma, Pancreatic Ductal; Colforsin; Cyclic AMP-Dependent Protein Kinases; Endopeptidases; Enzyme Inhibitors; Epitopes; Gene Expression Regulation, Neoplastic; Glycosylation; Humans; Immunoenzyme Techniques; Mercaptoethanol; Molecular Sequence Data; Mucin-1; Oxidation-Reduction; Pancreatic Neoplasms; Periodic Acid; Protein Conformation; Protein Processing, Post-Translational; Tumor Cells, Cultured | 2000 |
Studies of insulin secretory responses and of arachidonic acid incorporation into phospholipids of stably transfected insulinoma cells that overexpress group VIA phospholipase A2 (iPLA2beta ) indicate a signaling rather than a housekeeping role for iPLA2b
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Arachidonic Acid; Colforsin; Enzyme Inhibitors; Glucose; Group VI Phospholipases A2; Humans; Insulin; Insulin Secretion; Insulinoma; Kinetics; Mice; Naphthalenes; Pancreatic Neoplasms; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Phospholipids; Pyrones; Rats; Recombinant Proteins; Signal Transduction; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity; Transfection; Tumor Cells, Cultured | 2001 |
The expression and regulation of depolarization-activated K+ channels in the insulin-secreting cell line INS-1.
Topics: 1-Methyl-3-isobutylxanthine; 4-Aminopyridine; 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Animals; Calcium; Colforsin; Electric Conductivity; Gene Expression Regulation; Insulin; Insulin Secretion; Insulinoma; Pancreatic Neoplasms; Potassium Channel Blockers; Potassium Channels; Quaternary Ammonium Compounds; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetraethylammonium; Tolbutamide; Tumor Cells, Cultured | 2001 |
Antiproliferative actions of growth hormone-releasing hormone antagonists on MiaPaCa-2 human pancreatic cancer cells involve cAMP independent pathways.
Topics: Adenylyl Cyclases; Animals; Cell Division; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Glucagon; Growth Hormone-Releasing Hormone; Humans; Male; Mice; Mice, Nude; Muscles; Neoplasm Transplantation; Neuropeptides; Pancreatic Neoplasms; Pituitary Adenylate Cyclase-Activating Polypeptide; Radioimmunoassay; Secretin; Signal Transduction; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 2001 |
cAMP protection of pancreatic cancer cells against apoptosis induced by ERK inhibition.
Topics: 1-Methyl-3-isobutylxanthine; Apoptosis; bcl-X Protein; Caspases; CDC2-CDC28 Kinases; Cell Adhesion; Cell Cycle; Cell Survival; Colforsin; Culture Media; Cyclic AMP; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Gene Expression Regulation, Neoplastic; Histones; Humans; Mitogen-Activated Protein Kinases; Pancreatic Neoplasms; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-bcl-2; Retinoblastoma Protein; Tumor Cells, Cultured | 2001 |
GRP-receptor-mediated signal transduction, gene expression and DNA synthesis in the human pancreatic adenocarcinoma cell line HPAF.
Topics: Adenocarcinoma; Blotting, Northern; Bombesin; Calcium; Cell Membrane; Cloning, Molecular; Colforsin; Cyclic AMP; DNA; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; Image Processing, Computer-Assisted; Pancreatic Neoplasms; Protein Biosynthesis; Receptors, Bombesin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Spectrometry, Fluorescence; Time Factors; Tumor Cells, Cultured | 2001 |
Therapeutic differentiation of tumor-derived insulin-producing cells selected for resistance to diabetogenic drugs.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Differentiation; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Drug Resistance; Glucose; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Kinetics; Pancreatic Neoplasms; Rats; Streptozocin; Tumor Cells, Cultured | 2000 |
Glucose and forskolin regulate IAPP gene expression through different signal transduction pathways.
Topics: Adenylyl Cyclase Inhibitors; Amyloid; Blotting, Northern; Carcinoma, Pancreatic Ductal; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Glucose; Humans; Islet Amyloid Polypeptide; Isoquinolines; Pancreatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2001 |
cAMP-regulated guanine nucleotide exchange factor II (Epac2) mediates Ca2+-induced Ca2+ release in INS-1 pancreatic beta-cells.
Topics: Animals; Caffeine; Calcium; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Exenatide; Gene Expression; Guanine Nucleotide Exchange Factors; Insulinoma; Ion Channel Gating; Islets of Langerhans; Pancreatic Neoplasms; Peptides; Phosphodiesterase Inhibitors; Rats; Ryanodine Receptor Calcium Release Channel; Transfection; Tumor Cells, Cultured; Venoms | 2001 |
Stimulation of insulin secretion and associated nuclear accumulation of iPLA(2)beta in INS-1 insulinoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Nucleus; Colforsin; Cyclic AMP-Dependent Protein Kinases; Fluorescent Antibody Technique; Gene Expression; Glucose; Glycosylation; Group VI Phospholipases A2; Insulin; Insulin Secretion; Insulinoma; Kinetics; Pancreatic Neoplasms; Phospholipases A; Phosphorylation; Rats; Signal Transduction; Transfection; Tumor Cells, Cultured | 2002 |
Secretion of MUC5AC mucin from pancreatic cancer cells in response to forskolin and VIP.
Topics: Colforsin; Gastrointestinal Agents; Humans; Mucin 5AC; Mucins; Pancreatic Neoplasms; Protein Kinase C; Signal Transduction; Tumor Cells, Cultured; Up-Regulation; Vasoactive Intestinal Peptide | 2002 |
Expression of dopamine receptors and transporter in neuroendocrine gastrointestinal tumor cells.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Base Sequence; Biological Transport; Colforsin; Cyclic AMP; DNA Primers; Dopamine; Dopamine Plasma Membrane Transport Proteins; Gastrointestinal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Nerve Tissue Proteins; Neuroendocrine Tumors; Pancreatic Neoplasms; Quinpirole; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 2002 |
The effects of amylin on insulin secretion from Rin m5F cells and glycogen synthesis and lipogenesis in rat primary cultured hepatocytes.
Topics: Acetates; Amyloid; Animals; Arginine; Blood Glucose; Cell Line; Cells, Cultured; Colforsin; Cyclic AMP; DNA Replication; Glucose; Glyceraldehyde; Insulin; Insulin Secretion; Insulinoma; Islet Amyloid Polypeptide; Isoproterenol; Kinetics; Lipid Metabolism; Liver; Liver Glycogen; Male; Mice; Mice, Inbred Strains; Pancreatic Neoplasms; Rats; Rats, Inbred Strains; Thymidine | 1992 |
Stimulation of macrophage colony-stimulating factor synthesis by interleukin-1.
Topics: Bucladesine; Cholera Toxin; Colforsin; Cyclic AMP; Gene Expression Regulation, Neoplastic; Humans; Interleukin-1; Macrophage Colony-Stimulating Factor; Pancreatic Neoplasms; Pertussis Toxin; Protein Kinase C; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Signal Transduction; Theophylline; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1992 |
Interaction between phosphoinositide turnover system and cyclic AMP pathway for the secretion of pancreastatin and somatostatin from QGP-1N cells.
Topics: Adenoma, Islet Cell; Atropine; Bucladesine; Calcimycin; Carbachol; Cell Line; Chromogranin A; Colforsin; Cyclic AMP; Drug Synergism; Humans; Kinetics; Pancreatic Hormones; Pancreatic Neoplasms; Phosphatidylinositols; Somatostatin; Tetradecanoylphorbol Acetate; Theophylline; Tumor Cells, Cultured | 1992 |
Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Colforsin; Insulin; Insulin Secretion; Insulinoma; Membrane Potentials; Mercaptoethanol; Pancreatic Neoplasms; Rats; Tumor Cells, Cultured | 1992 |
Role of CFTR in lysosome acidification.
Topics: Adenocarcinoma; Adenosine Triphosphate; Bucladesine; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Line; Colforsin; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dextrans; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Hydrogen-Ion Concentration; Kinetics; Lysosomes; Membrane Proteins; Monensin; Mutation; Pancreatic Neoplasms; Spectrometry, Fluorescence | 1992 |
Regulation of plasma membrane recycling by CFTR.
Topics: Base Sequence; Cell Membrane; Chlorides; Colforsin; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; DNA; Endocytosis; Epithelium; Exocytosis; Gene Expression; Horseradish Peroxidase; Humans; Membrane Proteins; Molecular Sequence Data; Pancreatic Neoplasms; Transfection; Tumor Cells, Cultured; Wheat Germ Agglutinins | 1992 |
Galanin inhibits proinsulin gene expression stimulated by the insulinotropic hormone glucagon-like peptide-I(7-37) in mouse insulinoma beta TC-1 cells.
Topics: Adenylate Cyclase Toxin; Animals; Blotting, Northern; Cell Line; Chloramphenicol O-Acetyltransferase; Colforsin; Galanin; Gene Expression; Gene Expression Regulation, Neoplastic; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulinoma; Kinetics; Mice; Models, Biological; Pancreatic Neoplasms; Peptide Fragments; Peptides; Pertussis Toxin; Proinsulin; RNA, Neoplasm; Transfection; Virulence Factors, Bordetella | 1992 |
Insulin releasing effects of mastoparan and amphiphilic substance P receptor antagonists on RINm5F insulinoma cells.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Cholera Toxin; Colforsin; Exocytosis; GTP-Binding Proteins; Insulin; Insulin Secretion; Insulinoma; Intercellular Signaling Peptides and Proteins; Molecular Sequence Data; Neoplasm Proteins; Pancreatic Neoplasms; Peptide Fragments; Peptides; Pertussis Toxin; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Stimulation, Chemical; Structure-Activity Relationship; Substance P; Tumor Cells, Cultured; Virulence Factors, Bordetella; Wasp Venoms | 1992 |
CCK mRNA expression, pro-CCK processing, and regulated secretion of immunoreactive CCK peptides by rat insulinoma (RIN 5F) and mouse pituitary tumor (AtT-20) cells in culture.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blotting, Northern; Cholecystokinin; Chromatography, High Pressure Liquid; Colforsin; Cyclic AMP; Gene Expression; Insulinoma; Mice; Pancreatic Neoplasms; Pituitary Neoplasms; Protein Precursors; Rats; RNA, Messenger; Sincalide; Tumor Cells, Cultured | 1992 |
Role of extracellular magnesium in insulin secretion from rat insulinoma cells.
Topics: Animals; Calcium; Cell Line; Colforsin; Glyburide; Glyceraldehyde; Insulin; Insulin Secretion; Insulinoma; Kinetics; Magnesium; Pancreatic Neoplasms; Potassium Chloride; Rats; Tumor Cells, Cultured; Verapamil | 1992 |
Regulation of insulin secretion from beta-cell lines derived from transgenic mice insulinomas resembles that of normal beta-cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenoma, Islet Cell; Animals; Carbachol; Colforsin; Cyclic AMP; Drug Synergism; Glipizide; Glucose; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Kinetics; Mice; Mice, Transgenic; Pancreatic Neoplasms; Potassium; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Activation of PKC inhibits NaF-induced inositol phospholipid turnover in rat insulinoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Line; Colforsin; Cyclic AMP; Enzyme Activation; Inositol Phosphates; Insulin; Insulin Secretion; Insulinoma; Kinetics; Pancreatic Neoplasms; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Protein Kinase C; Rats; Sodium Fluoride; Tumor Cells, Cultured | 1990 |
Glucose induces insulin gene transcription in a murine pancreatic beta-cell line.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Line; Cell Nucleus; Colforsin; Cyclic AMP; Gallopamil; Genes; Glucose; Insulin; Insulinoma; Kinetics; Mice; Mice, Transgenic; Pancreatic Neoplasms; Promoter Regions, Genetic; Rats; Transcription, Genetic; Uridine Triphosphate | 1991 |
Effects of antiplatelet agents alone or in combinations on platelet aggregation and on liver metastases from a human pancreatic adenocarcinoma in the nude mouse.
Topics: Adenocarcinoma; Animals; Colforsin; Drug Interactions; Humans; Indomethacin; Ketoconazole; Liver Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Pancreatic Neoplasms; Platelet Aggregation; Platelet Aggregation Inhibitors; Tumor Cells, Cultured; Verapamil | 1991 |
Inhibition of renal membrane adenylate cyclase by extract of pancreatic cancer associated with humoral hypercalcemia of malignancy.
Topics: Adenylyl Cyclase Inhibitors; Bone and Bones; Cell Line; Cell Membrane; Chromatography, High Pressure Liquid; Colforsin; Cyclic AMP; Female; Humans; Hypercalcemia; Kidney; Middle Aged; Pancreatic Neoplasms; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Peptide Fragments; Proteins; Teriparatide | 1990 |
Inhibition of hepatic metastasis from a human pancreatic adenocarcinoma (RWP-2) in the nude mouse by prostacyclin, forskolin, and ketoconazole.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Colforsin; Epoprostenol; Humans; Ketoconazole; Liver Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Pancreatic Neoplasms; Platelet Aggregation; Platelet Aggregation Inhibitors; Tumor Cells, Cultured | 1990 |
P19, a hormonally regulated phosphoprotein of peptide hormone-producing cells: secretagogue-induced phosphorylation in AtT-20 mouse pituitary tumor cells and in rat and hamster insulinoma cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenoma, Islet Cell; Adrenocorticotropic Hormone; Animals; Colforsin; Corticotropin-Releasing Hormone; Cricetinae; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Glucagon; Insulinoma; Isoproterenol; Pancreatic Neoplasms; Phosphoproteins; Phosphorylation; Pituitary Neoplasms; Potassium; Rats; Tetradecanoylphorbol Acetate | 1986 |
Glucose stimulates insulin release without altering cyclic AMP production or inositolphospholipid turnover in freshly obtained human insulinoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenoma, Islet Cell; Carbachol; Colforsin; Cyclic AMP; Glucose; Humans; In Vitro Techniques; Insulin; Insulin Secretion; Insulinoma; Kinetics; Pancreatic Neoplasms; Phosphatidylinositols | 1987 |
HPLC analysis of somatostatin peptides secreted by a rat pancreatic endocrine cell line (RINT3): stimulation studies.
Topics: Adenoma, Islet Cell; Animals; Cell Line; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Colforsin; Culture Media; Indicators and Reagents; Pancreatic Neoplasms; Peptides; Rats; Somatostatin; Spectrophotometry, Ultraviolet; Tetradecanoylphorbol Acetate | 1989 |
Unregulated secretion of an exogenous glycotripeptide by rat islets and HIT cells.
Topics: Adenoma, Islet Cell; Animals; Cell Line; Colforsin; Egtazic Acid; Glucose; Glycopeptides; In Vitro Techniques; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Kinetics; Male; Pancreatic Neoplasms; Rats | 1988 |
Distribution of somatostatin receptors in RINm5F insulinoma cells.
Topics: Adenoma, Islet Cell; Animals; Cell Fractionation; Cell Membrane; Colforsin; Cytoplasmic Granules; Cytosol; Glucagon; Glyceraldehyde; Insulin; Insulin Secretion; Insulinoma; Iodine Radioisotopes; Kinetics; Leucine; Microsomes; Pancreatic Neoplasms; Rats; Receptors, Neurotransmitter; Receptors, Somatostatin; Somatostatin; Tumor Cells, Cultured | 1988 |