colforsin has been researched along with Breast Neoplasms in 63 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (6.35) | 18.7374 |
| 1990's | 25 (39.68) | 18.2507 |
| 2000's | 21 (33.33) | 29.6817 |
| 2010's | 13 (20.63) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Burra, S; David Krupadanam, GL; Kancha, RK; Rao, CP; Vijay Kumar, P; Voora, V | 1 |
| Bunch, T; Fordyce, C; Hassounah, NB; McDermott, KM; Nagle, R; Nunez, M; Roe, D | 1 |
| Abbondanza, C; Avvedimento, EV; Di Santi, A; Migliaccio, A; Ombra, MN; Perillo, B | 1 |
| Bierie, B; Kober, KI; Krall, JA; Pattabiraman, DR; Reinhardt, F; Tam, WL; Thiru, P; Weinberg, RA; Zill, C | 1 |
| Ford, BM; Franks, LN; Prather, PL; Radominska-Pandya, A | 1 |
| Chen, Q; Dong, C; Frasch, T; Hill, SM; Lai, L; Mao, L; Rowan, B; Yuan, L | 1 |
| Brown, KA; Hunger, NI; McInnes, KJ; Oakhill, JS; Simpson, ER; Steinberg, GR | 1 |
| Abbruzzese, A; Caraglia, M; Chiosi, E; Di Gesto, D; Illiano, F; Illiano, G; Marra, M; Naviglio, S; Romano, M; Sorrentino, A; Sorvillo, L; Spina, A | 1 |
| Chioni, AM; Djamgoz, MB; Grose, R; Shao, D | 1 |
| Ali, M; Amlal, H; Balasubramaniam, A; Haider, KH; Sheriff, S; Yahya, A | 1 |
| Chiosi, E; Di Gesto, D; Giordano, A; Illiano, F; Illiano, G; Naviglio, S; Spina, A | 1 |
| Fiorio Pla, A; Genazzani, A; Genova, T; Munaron, L; Pupo, E; Tomatis, C; Zaninetti, R | 1 |
| Brown, EB; Madden, KS; Szpunar, MJ | 1 |
| Chand, AL; Clyne, CD; Herridge, KA; Howard, TL; Simpson, ER | 1 |
| Dong, Y; Edwards, DP; Gao, R; Liu, X; Nishi, Y; Rowan, BG; Wabitsch, M; Yanase, T; Yu, Q; Zhao, L | 1 |
| Bauer, E; Dittmer, A; Dittmer, J; Leyh, B; Oerlecke, I | 1 |
| Cheng, CK; Chow, BK; Leung, PC | 1 |
| Chakrabarti, S; Chakraborty, C; Lala, PK; Timoshenko, AV; Xu, G | 1 |
| Richards, JS; Sriraman, V | 1 |
| Karami-Tehrani, F; Panjehpour, M | 1 |
| Arturi, F; Bruno, R; Ferretti, E; Filetti, S; Gulino, A; Lacroix, L; Mattei, T; Presta, I; Russo, D; Scarpelli, D; Scipioni, A; Tosi, E | 1 |
| Carrasco, N; De la Vieja, A; Dohán, O | 1 |
| Dittmer, A; Dittmer, J; Schunke, D; Span, PN; Sweep, F; Thomssen, C; Vetter, M | 1 |
| Amlal, H; Balasubramaniam, A; Faroqui, S; Sheriff, S | 1 |
| Kobayashi, Y; Obara, Y; Yonezawa, T | 1 |
| Al-Dhaheri, MH; Rowan, BG | 1 |
| Chiffer, RC; Leuba, SH; Rodriguez-Collazo, P; Smith, CL; Snyder, SK; Zlatanova, J | 1 |
| Brueggemeier, RW; Díaz-Cruz, ES; Landini, S; Su, B | 1 |
| Eppenberger, U; Küng, W; Roos, W | 1 |
| Israël, L; Magnien, V; Planchon, P; Starzec, AB; Veber, N | 1 |
| Bøe, R; Døskeland, SO; Gjertsen, BT; Vintermyr, OK | 1 |
| Moore, EE; Stroop, SD | 1 |
| Bona, BJ; Borror, KC; DeFranco, DB; Moyer, ML; Nordeen, SK | 1 |
| Aakvaag, A; Brustugun, OT; Bøe, R; Døskeland, SO; Maronde, E; Vintermyr, OK | 1 |
| Planchon, P; Prévost, G; Starzec, A; Veber, N | 1 |
| Andreasen, PA; Christensen, L; Knudsen, H; Olesen, T; Riccio, A; Ungaro, P | 1 |
| Kimura, N; Nagata, N; Shimada, N; Yasutomo, Y | 1 |
| Body, JJ; Lacroix, M; Siwek, B | 1 |
| Agarwal, VR; Mendelson, CR; Simpson, ER; Zhao, Y | 1 |
| Bandoh, S; Maruyama, K; Ohkura, N; Sasaki, K; Tsukada, T; Yamaguchi, K | 1 |
| Body, JJ; Lacroix, M | 1 |
| Banko, M; Fu, R; Lowe, WL | 1 |
| Abraham, JM; Balcer-Kubiczek, EK; Han, LH; Harrison, GH; Meltzer, SJ; Shi, ZM; Zhang, XF | 1 |
| David, F; Eppenberger, U; Liu, R; Mueller, H | 1 |
| Bale, TL; Dorsa, DM | 2 |
| Mercurio, AM; O'Connor, KL; Shaw, LM | 1 |
| Gray-Bablin, J; Herliczek, TW; Keyomarsi, K; Rao, S | 1 |
| Chen, S; Zhou, D | 1 |
| Niles, LP; Wang, J | 1 |
| De Petrocellis, L; Di Marzo, V; Galve-Roperh, I; Guzmán, M; Melck, D; Rueda, D | 1 |
| Brent, GA; Huang, M; Johnson, LS; Kogai, T; Schultz, JJ | 1 |
| Byrne, IM; Flanagan, L; Tenniswood, MP; Welsh, J | 1 |
| Epstein, RJ; Gulliford, T; Huang, G; Ouyang, X; Smith, G; Zhang, H | 1 |
| Bifulco, M; Bisogno, T; De Petrocellis, L; Di Marzo, V; Melck, D; Orlando, P; Vogel, Z; Zagoory, O | 1 |
| Atlas, E; Mueller, CR; Stramwasser, M | 1 |
| Adessi, GL; Bermont, L; Chezy, E; Lamielle-Musard, F; Weisz, A | 1 |
| Fuchimoto, S; Orita, K; Shiiki, S | 1 |
| Dupont, MA; Gas, N; Guilbaud, NF; Valette, A | 1 |
| Aakvaag, A; Lahooti, H; Thorsen, T | 1 |
| Findlay, DM; Michelangeli, VP; Robinson, PJ | 1 |
| Abita, JP; Calvo, F; Cost, H; de Cremoux, P; Gauville, C; Lagier, G; Lechat, P | 1 |
| Durham, JP; Fontana, JA; Miksis, G; Miranda, DM | 1 |
63 other study(ies) available for colforsin and Breast Neoplasms
| Article | Year |
|---|---|
Synthesis of novel forskolin isoxazole derivatives with potent anti-cancer activity against breast cancer cell lines.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Colforsin; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Isoxazoles; MCF-7 Cells; Molecular Structure; Structure-Activity Relationship | 2017 |
Inhibition of Ciliogenesis Promotes Hedgehog Signaling, Tumorigenesis, and Metastasis in Breast Cancer.
Topics: Animals; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Cilia; Colforsin; Female; Gene Expression Regulation, Neoplastic; Hedgehog Proteins; Humans; Mice; Neoplasm Grading; Neoplasm Metastasis; NIH 3T3 Cells; Signal Transduction | 2017 |
Retinoic acid impairs estrogen signaling in breast cancer cells by interfering with activation of LSD1 via PKA.
Topics: Breast Neoplasms; Catalytic Domain; Chromatin; Colforsin; Cyclic AMP-Dependent Protein Kinases; Estrogens; Female; Flavonoids; Histone Demethylases; Histones; Humans; Isoquinolines; MAP Kinase Signaling System; MCF-7 Cells; Methylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering; Sulfonamides; Transcription, Genetic; Tretinoin | 2013 |
Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability.
Topics: Adenosine Monophosphate; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Transformation, Neoplastic; Cholera Toxin; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Epigenesis, Genetic; Epithelial Cells; Epithelial-Mesenchymal Transition; Female; Histone Demethylases; Homeodomain Proteins; Humans; Mammary Glands, Human; Mesoderm; Mice; Neoplastic Stem Cells; Second Messenger Systems; Xenograft Model Antitumor Assays | 2016 |
Tamoxifen Isomers and Metabolites Exhibit Distinct Affinity and Activity at Cannabinoid Receptors: Potential Scaffold for Drug Development.
Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Breast Neoplasms; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Cyclohexanols; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Indoles; Isomerism; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Selective Estrogen Receptor Modulators; Tamoxifen | 2016 |
The Galphai and Galphaq proteins mediate the effects of melatonin on steroid/thyroid hormone receptor transcriptional activity and breast cancer cell proliferation.
Topics: Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Colforsin; Cyclic AMP; Cyclic GMP; Estrogens; Female; Gene Expression Regulation; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Immunoprecipitation; Luciferases; Melatonin; Phosphorus Radioisotopes; Radioimmunoassay; Receptor, Melatonin, MT1; Receptors, Estrogen; Receptors, Retinoic Acid; Receptors, Thyroid Hormone; Retinoic Acid Receptor alpha; Transcription, Genetic; Transfection | 2008 |
Subcellular localization of cyclic AMP-responsive element binding protein-regulated transcription coactivator 2 provides a link between obesity and breast cancer in postmenopausal women.
Topics: Aromatase; Breast Neoplasms; Colforsin; DNA Primers; Estradiol; Estrogens; Female; Genes, Reporter; Homeostasis; Humans; Leptin; Mammaplasty; Obesity; Polymerase Chain Reaction; Postmenopause; Restriction Mapping; Stromal Cells; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection | 2009 |
Leptin enhances growth inhibition by cAMP elevating agents through apoptosis of MDA-MB-231 breast cancer cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Apoptosis; Breast Neoplasms; Carbazoles; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclin-Dependent Kinase Inhibitor p27; Female; G1 Phase; Humans; Leptin; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Signal Transduction | 2009 |
Protein kinase A and regulation of neonatal Nav1.5 expression in human breast cancer cells: activity-dependent positive feedback and cellular migration.
Topics: Animals; Breast Neoplasms; Carbazoles; Cell Line, Tumor; Cell Movement; Colforsin; Cyclic AMP-Dependent Protein Kinases; Feedback, Physiological; Gene Expression Regulation, Neoplastic; Humans; Infant, Newborn; Muscle Proteins; NAV1.5 Voltage-Gated Sodium Channel; Neoplasm Invasiveness; Phosphorylation; Pyrroles; Rats; Sodium Channels; Stromal Cells; Tetrodotoxin; Up-Regulation | 2010 |
Neuropeptide Y Y5 receptor promotes cell growth through extracellular signal-regulated kinase signaling and cyclic AMP inhibition in a human breast cancer cell line.
Topics: Binding Sites; Binding, Competitive; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Naphthalenes; Neoplasm Invasiveness; Neuropeptide Y; Phosphorylation; Pyrimidines; Receptors, Neuropeptide Y | 2010 |
Leptin potentiates antiproliferative action of cAMP elevation via protein kinase A down-regulation in breast cancer cells.
Topics: Antineoplastic Agents; Breast Neoplasms; Carbazoles; Cell Line, Tumor; Cell Proliferation; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Activators; Female; Humans; Leptin; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Protein Kinase Inhibitors; Pyrroles; Recombinant Proteins; Signal Transduction; STAT3 Transcription Factor; Time Factors; Up-Regulation | 2010 |
Multiple roles of protein kinase a in arachidonic acid-mediated Ca2+ entry and tumor-derived human endothelial cell migration.
Topics: Arachidonic Acid; Breast Neoplasms; Calcium; Calcium Signaling; Carcinoma, Lobular; Cell Line, Tumor; Cell Movement; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endothelial Cells; Enzyme Activation; Female; Humans; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation | 2010 |
β-Adrenergic receptors (β-AR) regulate VEGF and IL-6 production by divergent pathways in high β-AR-expressing breast cancer cell lines.
Topics: Adenocarcinoma; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Female; Humans; Interleukin-6; Receptors, Adrenergic, beta; Signal Transduction; Vascular Endothelial Growth Factor A | 2011 |
Tissue-specific regulation of aromatase promoter II by the orphan nuclear receptor LRH-1 in breast adipose stromal fibroblasts.
Topics: Adipose Tissue; Aromatase; Breast; Breast Neoplasms; Chromatin Immunoprecipitation; Colforsin; Dinoprostone; Female; Fibroblasts; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Knockout Techniques; Humans; Organ Specificity; Postmenopause; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; RNA, Small Interfering; Stromal Cells; Tetradecanoylphorbol Acetate; Transfection | 2011 |
Methylseleninic acid is a novel suppressor of aromatase expression.
Topics: Adenylyl Cyclases; Adipocytes; Antineoplastic Agents, Hormonal; Aromatase; Breast Neoplasms; Cell Line; Cell Line, Tumor; Colforsin; Dexamethasone; Down-Regulation; Enzyme Activators; Enzyme Induction; Female; Glucocorticoids; Humans; Neoplasm Proteins; Organoselenium Compounds; Ovarian Neoplasms; Ovary; Promoter Regions, Genetic; Recombinant Proteins; RNA, Messenger | 2012 |
Cyclic AMP enhances TGFβ responses of breast cancer cells by upregulating TGFβ receptor I expression.
Topics: Adaptor Proteins, Signal Transducing; Blotting, Western; Breast Neoplasms; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Coculture Techniques; Colforsin; Cyclic AMP; Cyclin-Dependent Kinase Inhibitor p21; Female; Gene Expression Regulation, Neoplastic; Humans; Mesenchymal Stem Cells; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Smad3 Protein; Transcription Factors; Transforming Growth Factor beta; YAP-Signaling Proteins | 2013 |
An activator protein 1-like motif mediates 17beta-estradiol repression of gonadotropin-releasing hormone receptor promoter via an estrogen receptor alpha-dependent mechanism in ovarian and breast cancer cells.
Topics: Base Sequence; Binding Sites; Breast Neoplasms; Cell Line, Tumor; Colforsin; DNA, Neoplasm; Estradiol; Estrogen Receptor alpha; Female; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Ovarian Neoplasms; Promoter Regions, Genetic; Receptors, Estrogen; Receptors, LHRH; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic | 2003 |
Role of prostaglandin E2 receptors in migration of murine and human breast cancer cells.
Topics: Alprostadil; Animals; Breast Neoplasms; Carcinoma; Cell Movement; Colforsin; Cyclic AMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Dose-Response Relationship, Drug; Female; Humans; Indoles; Isoenzymes; Mammary Neoplasms, Experimental; Membrane Proteins; Mice; Neoplasm Invasiveness; Prostaglandin-Endoperoxide Synthases; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Tumor Cells, Cultured; Up-Regulation; Xanthenes; Xanthones | 2003 |
Cathepsin L gene expression and promoter activation in rodent granulosa cells.
Topics: Animals; Base Sequence; Binding Sites; Breast Neoplasms; Cathepsin L; Cathepsins; Cell Line; Chorionic Gonadotropin; Colforsin; CREB-Binding Protein; Cysteine Endopeptidases; DNA; DNA-Binding Proteins; Drosophila; Female; Gene Deletion; Gene Expression Regulation; Gonadotropins, Equine; Granulosa Cells; Humans; In Situ Hybridization; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Mutagenesis, Site-Directed; Nuclear Proteins; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Sp1 Transcription Factor; Sp3 Transcription Factor; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription Factors; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 2004 |
An adenosine analog (IB-MECA) inhibits anchorage-dependent cell growth of various human breast cancer cell lines.
Topics: Adenosine; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Colforsin; Cyclic AMP; Female; Gene Expression Regulation, Neoplastic; Humans; Receptor, Adenosine A3; Signal Transduction | 2004 |
Regulation of iodide uptake and sodium/iodide symporter expression in the mcf-7 human breast cancer cell line.
Topics: Breast Neoplasms; Cell Line, Tumor; Colforsin; Estradiol; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Iodides; Oxytocin; Prolactin; Symporters | 2005 |
Hydrocortisone and purinergic signaling stimulate sodium/iodide symporter (NIS)-mediated iodide transport in breast cancer cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Biological Transport; Breast Neoplasms; Cell Membrane; Cells, Cultured; Colforsin; Female; Humans; Hydrocortisone; Iodides; Phosphodiesterase Inhibitors; Signal Transduction; Symporters; Thyroid Gland; Tretinoin | 2006 |
Parathyroid hormone-related protein regulates tumor-relevant genes in breast cancer cells.
Topics: Biopsy; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colforsin; Gene Expression Regulation, Neoplastic; Humans; Integrin alpha6; Kisspeptins; Parathyroid Hormone-Related Protein; Plasminogen Activator Inhibitor 1; RNA Interference; RNA, Small Interfering; Tumor Suppressor Proteins | 2006 |
Estrogen up-regulates neuropeptide Y Y1 receptor expression in a human breast cancer cell line.
Topics: Binding, Competitive; Breast Neoplasms; Calcium; Cell Line, Tumor; Cell Membrane; Colforsin; Cyclic AMP; Cycloheximide; Estrogen Receptor alpha; Estrogens; Gene Expression Regulation, Neoplastic; Humans; Iodine Radioisotopes; Neuropeptide Y; Receptors, Neuropeptide Y; RNA, Messenger; Up-Regulation | 2006 |
Short-chain fatty acids induce acute phosphorylation of the p38 mitogen-activated protein kinase/heat shock protein 27 pathway via GPR43 in the MCF-7 human breast cancer cell line.
Topics: Acetates; Breast Neoplasms; Butyrates; Calcium; Cell Line, Tumor; Colforsin; Cyclic AMP; Fatty Acids, Volatile; Female; Heat-Shock Proteins; Humans; p38 Mitogen-Activated Protein Kinases; Pertussis Toxin; Phosphorylation; Propionates; Receptor Cross-Talk; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Second Messenger Systems; Signal Transduction | 2007 |
Protein kinase A exhibits selective modulation of estradiol-dependent transcription in breast cancer cells that is associated with decreased ligand binding, altered estrogen receptor alpha promoter interaction, and changes in receptor phosphorylation.
Topics: 1-Methyl-3-isobutylxanthine; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclin D1; Estradiol; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; HSP90 Heat-Shock Proteins; Humans; Intracellular Signaling Peptides and Proteins; Ligands; Phosphorylation; Promoter Regions, Genetic; Signal Transduction; Tamoxifen; Transcription, Genetic | 2007 |
cAMP signaling induces rapid loss of histone H3 phosphorylation in mammary adenocarcinoma-derived cell lines.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Genes, cdc; Histones; Humans; Mammary Neoplasms, Animal; Methylation; Mice; Phosphorylation; Regulatory Elements, Transcriptional; Signal Transduction | 2008 |
Suppression of aromatase in human breast cells by a cyclooxygenase-2 inhibitor and its analog involves multiple mechanisms independent of cyclooxygenase-2 inhibition.
Topics: Aromatase; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Colforsin; Cyclooxygenase 2 Inhibitors; Dexamethasone; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Microsomes; Molecular Structure; Nitrobenzenes; Phorbols; Sulfonamides; Testosterone | 2008 |
Growth stimulation of human breast cancer MCF-7 cells by dibutyryl cyclic AMP.
Topics: Breast Neoplasms; Bucladesine; Cell Division; Cell Line; Colforsin; Diterpenes; Estradiol; Female; Humans | 1983 |
Alteration of prostaglandin E receptors in advanced breast tumour cell lines.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Breast Neoplasms; Cell Differentiation; Cell Division; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Estradiol; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Receptors, Prostaglandin E; Tumor Cells, Cultured | 1995 |
8-Chloro-cAMP induces apoptotic cell death in a human mammary carcinoma cell (MCF-7) line.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenocarcinoma; Adenosine Deaminase; Amino Acid Sequence; Apoptosis; Biotransformation; Breast Neoplasms; Chromatin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA Damage; Ethers, Cyclic; Female; Humans; Marine Toxins; Microvilli; Molecular Sequence Data; Necrosis; Okadaic Acid; Organelles; Oxazoles; Phosphoprotein Phosphatases | 1995 |
Intracellular calcium increases mediated by a recombinant human calcitonin receptor.
Topics: Adenylyl Cyclases; Amyloid; Animals; Breast Neoplasms; Calcitonin; Calcitonin Gene-Related Peptide; Calcium; Calcium Channel Blockers; Carcinoma; Cations, Divalent; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Hydrogen-Ion Concentration; Inositol Phosphates; Islet Amyloid Polypeptide; Receptors, Calcitonin; Recombinant Proteins; Transfection; Tumor Cells, Cultured | 1995 |
Modulation of cell signaling pathways can enhance or impair glucocorticoid-induced gene expression without altering the state of receptor phosphorylation.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Breast Neoplasms; Chloramphenicol O-Acetyltransferase; Colforsin; Dexamethasone; Ethers, Cyclic; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Genetic Vectors; Humans; Luciferases; Mammary Tumor Virus, Mouse; Okadaic Acid; Phosphopeptides; Phosphorylation; Promoter Regions, Genetic; Protein Tyrosine Phosphatases; Receptors, Glucocorticoid; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1993 |
Cyclic adenosine monophosphate (cAMP) analogs 8-Cl- and 8-NH2-cAMP induce cell death independently of cAMP kinase-mediated inhibition of the G1/S transition in mammary carcinoma cells (MCF-7).
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Breast Neoplasms; Cell Death; Cell Division; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA, Neoplasm; Female; G1 Phase; Humans; Protein Conformation; Protein Serine-Threonine Kinases; S Phase; Thymidine; Tumor Cells, Cultured | 1995 |
Evidence for a growth effect of epidermal growth factor on MDA-MB-231 breast cancer cells.
Topics: Breast Neoplasms; Cell Cycle; Cholera Toxin; Colforsin; Cyclic AMP; Epidermal Growth Factor; Female; Humans; Mitosis; Time Factors; Tumor Cells, Cultured | 1994 |
A common response element mediates differential effects of phorbol esters and forskolin on type-1 plasminogen activator inhibitor gene expression in human breast carcinoma cells.
Topics: Base Sequence; Binding Sites; Breast Neoplasms; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Molecular Sequence Data; Plasminogen Activator Inhibitor 1; Promoter Regions, Genetic; Protein Binding; Protein Kinase C; Proto-Oncogene Proteins c-jun; Signal Transduction; Sp1 Transcription Factor; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Estradiol up-regulates the stimulatory GTP-binding protein expression in the MCF-7 human mammary carcinoma cell line.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Breast Neoplasms; Calcitonin; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Estradiol; GTP-Binding Proteins; Humans; Isoproterenol; Pertussis Toxin; Tumor Cells, Cultured; Up-Regulation; Virulence Factors, Bordetella | 1993 |
Effects of secretory products of breast cancer cells on osteoblast-like cells.
Topics: Adenocarcinoma; Breast Neoplasms; Cell Division; Colforsin; Culture Media, Conditioned; Cyclic AMP; Dinoprostone; Female; Humans; Osteoblasts; Osteolysis; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Proteins; Transforming Growth Factor beta; Tumor Cells, Cultured | 1996 |
Estrogen biosynthesis proximal to a breast tumor is stimulated by PGE2 via cyclic AMP, leading to activation of promoter II of the CYP19 (aromatase) gene.
Topics: Adipose Tissue; Aromatase; Breast Neoplasms; Bucladesine; Colforsin; Cyclic AMP; Dinoprostone; Estrogens; Female; Gene Expression Regulation; Humans; Promoter Regions, Genetic; Stromal Cells; Tetradecanoylphorbol Acetate | 1996 |
Retinoic acids differentially regulate NOR-1 and its closely related orphan nuclear receptor genes in breast cancer cell line MCF-7.
Topics: Alitretinoin; Breast Neoplasms; Colforsin; Cycloheximide; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Nerve Tissue Proteins; Nuclear Receptor Subfamily 4, Group A, Member 1; Nuclear Receptor Subfamily 4, Group A, Member 2; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Receptors, Thyroid Hormone; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Tretinoin; Tumor Cells, Cultured | 1997 |
Regulation of c-fos and c-jun expression by calcitonin in human breast cancer cells.
Topics: Blotting, Northern; Breast Neoplasms; Calcitonin; Carcinogens; Cell Division; Colforsin; Dose-Response Relationship, Drug; Drug Interactions; Epidermal Growth Factor; Female; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Glycoproteins; Humans; Insulin; Isoquinolines; Metalloendopeptidases; Protein Biosynthesis; Protein Kinase Inhibitors; Proteins; Receptors, Calcitonin; RNA, Messenger; Sulfonamides; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinase-2; Tissue Inhibitor of Metalloproteinases; Tumor Cells, Cultured | 1997 |
Growth factor-induced transcription via the serum response element is inhibited by cyclic adenosine 3',5'-monophosphate in MCF-7 breast cancer cells.
Topics: Breast Neoplasms; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Colforsin; Cyclic AMP; DNA-Binding Proteins; Epidermal Growth Factor; Female; Humans; Insulin-Like Growth Factor I; Kinetics; Luciferases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nuclear Proteins; Promoter Regions, Genetic; Recombinant Fusion Proteins; Serum Response Factor; Thionucleotides; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1997 |
Csa-19, a radiation-responsive human gene, identified by an unbiased two-gel cDNA library screening method in human cancer cells.
Topics: Age Factors; Blotting, Northern; Breast Neoplasms; Cloning, Molecular; Colforsin; Cyclosporine; DNA, Complementary; Dose-Response Relationship, Radiation; Down-Regulation; Gene Expression Regulation, Developmental; Gene Library; Genes, p53; HL-60 Cells; Humans; Molecular Sequence Data; Neutrons; Oncogenes; Tetradecanoylphorbol Acetate; Tissue Distribution; Tumor Cells, Cultured; X-Rays | 1997 |
Selective modulation of protein kinase A and protein kinase C activities in epidermal growth factor (EGF)-stimulated MCF-7 breast cancer cells.
Topics: Alkaloids; Benzophenanthridines; Blotting, Northern; Breast Neoplasms; Bucladesine; Cell Division; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Female; Gene Expression Regulation; Genes, fos; Genes, myc; Humans; Phenanthridines; Phorbol Esters; Protein Kinase C; Receptors, Cell Surface; Tumor Cells, Cultured | 1997 |
NGF, cyclic AMP, and phorbol esters regulate oxytocin receptor gene transcription in SK-N-SH and MCF7 cells.
Topics: Animals; Brain; Breast Neoplasms; Cloning, Molecular; Colforsin; Cyclic AMP; DNA-Binding Proteins; Female; Humans; Nerve Growth Factors; Neuroblastoma; Promoter Regions, Genetic; Rats; Receptors, Oxytocin; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1998 |
Release of cAMP gating by the alpha6beta4 integrin stimulates lamellae formation and the chemotactic migration of invasive carcinoma cells.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Antibodies; Antigens, Surface; Breast Neoplasms; Chemotaxis; Colforsin; Culture Media, Conditioned; Cyclic AMP; Female; Fibroblasts; Humans; Integrin alpha6beta4; Integrins; Kinetics; Lysophospholipids; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Pyrrolidinones; Rolipram; Signal Transduction; Tumor Cells, Cultured | 1998 |
Transcriptional regulation of the oxytocin receptor gene.
Topics: Breast Neoplasms; Colforsin; Dexamethasone; Estrogens; Female; Gene Expression Regulation; Genes, Reporter; Humans; Mutagenesis, Site-Directed; Nerve Growth Factors; Promoter Regions, Genetic; Receptors, Oxytocin; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1998 |
The biphasic induction of p21 and p27 in breast cancer cells by modulators of cAMP is posttranscriptionally regulated and independent of the PKA pathway.
Topics: 1-Methyl-3-isobutylxanthine; Breast Neoplasms; Cell Cycle Proteins; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; Female; Humans; Isoquinolines; Kinetics; Lovastatin; Microtubule-Associated Proteins; Protein Processing, Post-Translational; Sulfonamides; Transfection; Tumor Cells, Cultured; Tumor Suppressor Proteins | 1999 |
Identification and characterization of a cAMP-responsive element in the region upstream from promoter 1.3 of the human aromatase gene.
Topics: Aromatase; Base Sequence; Breast Neoplasms; Colforsin; Cross-Linking Reagents; Cyclic AMP; DNA Mutational Analysis; DNA-Binding Proteins; Enzyme Induction; Exons; Female; Humans; Molecular Sequence Data; Nuclear Proteins; Promoter Regions, Genetic; Protein Binding; Response Elements; RNA, Messenger; Tumor Cells, Cultured | 1999 |
Diazepam inhibits forskolin-stimulated adenylyl cyclase activity in human tumour cells.
Topics: Adenylyl Cyclase Inhibitors; Anti-Anxiety Agents; Breast Neoplasms; Cell Membrane; Colforsin; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Humans; Melanoma; Tumor Cells, Cultured | 1999 |
Involvement of the cAMP/protein kinase A pathway and of mitogen-activated protein kinase in the anti-proliferative effects of anandamide in human breast cancer cells.
Topics: Arachidonic Acids; Breast Neoplasms; Cell Division; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Endocannabinoids; Flavonoids; Humans; Mitogen-Activated Protein Kinases; Nerve Growth Factor; Piperidines; Polyunsaturated Alkamides; Prolactin; Proto-Oncogene Proteins c-raf; Pyrazoles; Receptors, Prolactin; Rimonabant; Tumor Cells, Cultured | 1999 |
Retinoic acid induces sodium/iodide symporter gene expression and radioiodide uptake in the MCF-7 breast cancer cell line.
Topics: Alitretinoin; Animals; Antineoplastic Agents; Breast Neoplasms; Carrier Proteins; Cell Line; Colforsin; Down-Regulation; Female; Humans; Iodides; Iodine Radioisotopes; Kinetics; Membrane Proteins; Oxytocin; Prolactin; Rats; Sodium Iodide; Symporters; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured | 2000 |
Identification of a hormone-responsive promoter immediately upstream of exon 1c in the human vitamin D receptor gene.
Topics: Base Sequence; Binding Sites; Breast Neoplasms; Cholecalciferol; Colforsin; Estradiol; Estrogen Antagonists; Estrogens; Exons; Gene Expression Regulation; Hormones; Humans; Molecular Sequence Data; Promoter Regions, Genetic; Receptors, Calcitriol; Response Elements; Tamoxifen; TATA Box; Transcription Factors; Transfection; Tretinoin; Tumor Cells, Cultured | 2000 |
Association of ErbB2 Ser1113 phosphorylation with epidermal growth factor receptor co-expression and poor prognosis in human breast cancer.
Topics: Animals; Antibodies, Monoclonal; Becaplermin; Breast Neoplasms; Cells, Cultured; Colforsin; Epidermal Growth Factor; ErbB Receptors; Fluorescent Antibody Technique; Humans; Immunoblotting; Mice; Microscopy, Confocal; Phorbol 12,13-Dibutyrate; Phosphorylation; Phosphoserine; Platelet-Derived Growth Factor; Prognosis; Proto-Oncogene Proteins c-sis; Receptor, ErbB-2; Transfection; Vanadates | 2001 |
Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase and enhances the anti-proliferative effect of anandamide in human breast cancer cells.
Topics: Amides; Amidohydrolases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Arachidonic Acids; Blotting, Western; Breast Neoplasms; Camphanes; Cannabinoid Receptor Modulators; Cannabinoids; Capsaicin; Cell Division; Colforsin; COS Cells; Cyclic AMP; Dose-Response Relationship, Drug; Endocannabinoids; Ethanolamines; Glycerides; Humans; Hydrolysis; Inhibitory Concentration 50; Palmitic Acids; Polyunsaturated Alkamides; Protein Binding; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Reverse Transcriptase Polymerase Chain Reaction; Transfection; Tumor Cells, Cultured | 2001 |
A CREB site in the BRCA1 proximal promoter acts as a constitutive transcriptional element.
Topics: Activating Transcription Factor 1; Adenocarcinoma; Base Sequence; Binding Sites; Breast Neoplasms; Carcinoma, Hepatocellular; Colforsin; CpG Islands; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Dimerization; DNA Methylation; DNA-Binding Proteins; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Genes, BRCA1; Genes, Reporter; Humans; Liver Neoplasms; Molecular Sequence Data; Mutagenesis, Site-Directed; Promoter Regions, Genetic; Protein Binding; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 2001 |
17beta-estradiol inhibits forskolin-induced vascular endothelial growth factor promoter in MCF-7 breast adenocarcinoma cells.
Topics: Adenocarcinoma; Base Sequence; Breast Neoplasms; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA Primers; Endothelial Growth Factors; Estradiol; Gene Expression Regulation; Humans; Ligands; Lymphokines; Promoter Regions, Genetic; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
A comparison of the antitumor effects of natural human tumor necrosis factors alpha and beta: the roles of arachidonic acid metabolism and intracellular cAMP.
Topics: Arachidonic Acid; Arachidonic Acids; Breast Neoplasms; Colforsin; Colonic Neoplasms; Cyclic AMP; Dexamethasone; Female; Humans; Indomethacin; Lymphotoxin-alpha; Metyrapone; Phospholipases A; Phospholipases A2; Quinacrine; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1990 |
Effects of differentiation-inducing agents on maturation of human MCF-7 breast cancer cells.
Topics: Acetamides; Antigens, Neoplasm; Breast Neoplasms; Butyrates; Butyric Acid; Cell Differentiation; Cell Division; Colforsin; Dimethylformamide; Fluorescent Antibody Technique; Humans; Membrane Glycoproteins; Mucin-1; Receptors, Estrogen; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1990 |
Estradiol increases phosphorylation of the 90 kDa heat shock protein not associated with estradiol receptor in MCF-7 cells in culture.
Topics: Blotting, Western; Breast Neoplasms; Calcimycin; Colforsin; Estradiol; Heat-Shock Proteins; Humans; Phosphorylation; Receptors, Estrogen; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Protein kinase-C-induced down-regulation of calcitonin receptors and calcitonin-activated adenylate cyclase in T47D and BEN cells.
Topics: Adenylyl Cyclases; Breast Neoplasms; Calcitonin; Cell Line; Colforsin; Dinitrophenols; Down-Regulation; Enzyme Activation; Female; Humans; Kinetics; Lung Neoplasms; Protein Kinase C; Receptors, Calcitonin; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
1,25-Dihydroxycholecalciferol induces an increase in PGE1- and forskolin-stimulated cyclic-AMP production in T47D human breast cancer cell line.
Topics: Alprostadil; Breast Neoplasms; Calcitriol; Cell Division; Colforsin; Cyclic AMP; Humans; Tumor Cells, Cultured | 1987 |
Inhibition of human mammary carcinoma cell proliferation by retinoids and intracellular cAMP-elevating compounds.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Breast Neoplasms; Cell Division; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Humans; Papaverine; Retinoids; Stimulation, Chemical | 1987 |