Page last updated: 2024-08-23

colforsin and Asthma

colforsin has been researched along with Asthma in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19904 (15.38)18.7374
1990's8 (30.77)18.2507
2000's11 (42.31)29.6817
2010's2 (7.69)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Giembycz, MA; Hamed, O; Joshi, R; Mostafa, MM1
Chen, W; Huang, J; Liang, X; Liu, J; Ma, X; Nagao, N; Wang, J; Wang, Y; Weng, W1
Coelho, LP; Cordeiro, RS; da Costa, JC; Martins, MA; Olsen, PC; Silva, PM1
Black, JL; Boustany, S; Burgess, JK; Ge, Q; Johnson, PR1
Guadagnini, R; Jeulin, C; Marano, F1
Honjo, H; Ito, S; Kamiya, K; Kodama, I; Kume, H; Oguma, T; Shimokata, K; Takeda, N1
Ibe, BO; Portugal, AM; Raj, JU1
Edwards, MR; Haas, J; Johnson, M; Johnston, SL; Panettieri, RA1
Fatma, S; Grunstein, JS; Grunstein, MM; Hu, A; Nino, G1
Biamino, G; Friedrich, T; Huckauf, H; Lichey, I; Priesnitz, M; Usinger, P1
Albelda, SM; Lazaar, AL; Panettieri, RA; Puré, E1
Azevedo, I; Bachelet, M; de Blic, J; Galoppin, L; Scheinmann, P; Vargaftig, BB1
Alouan, LA; Armour, CL; Black, JL; Johnson, PR; Marthan, R; McKay, KO; Savineau, JP; Tunon de Lara, JM; Villanove, X1
Bauer, K; Dietersdorfer, F; Kaik, B; Kaik, G; Sertl, K1
Grunstein, MM; Hakonarson, H; Herrick, DJ; Serrano, PG1
Hiramatsu, K; Inagaki, N; Nagai, H; Shichijo, M; Shimizu, Y; Tagaki, K1
Dent, G; Djukanović, R; Hidi, R; Holgate, ST; Liu, E; Schudt, C; Timmermans, S1
Bonner, JC; Wang, YZ1
Knox, AJ; Pang, L1
Hasegawa, T; Hiramatsu, K; Ito, Y; Kitaichi, K; Kume, H; Shibata, E; Shimizu, Y; Suzuki, R; Takagi, K; Takeuchi, M; Yamaki, K; Yoshida, N1
Atherton, H; Bridges, RJ; Danahay, H; Jones, G; Poll, CT1
Balcarek, JM; Chilton, FH; Livi, GP; Torphy, TJ; Undem, BJ; White, JR1
Iizuka, K; Nakazawa, T; Yoshie, Y1
Criscuoli, M; Del Monte, M; Subissi, A1
Ozawa, T; Satake, T; Sugiyama, S; Takagi, K; Taki, F1
Goldie, RG; Papadimitriou, JM; Paterson, JW; Rigby, PJ; Self, HM; Spina, D1

Reviews

1 review(s) available for colforsin and Asthma

ArticleYear
Therapeutic potential of isozyme-selective phosphodiesterase inhibitors in the treatment of asthma.
    Advances in second messenger and phosphoprotein research, 1992, Volume: 25

    Topics: 1-Methyl-3-isobutylxanthine; 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Asthma; Colforsin; Cyclic AMP; Humans; Mast Cells; Mice; Pyrrolidinones; Rolipram

1992

Trials

1 trial(s) available for colforsin and Asthma

ArticleYear
Pharmacodynamic effects of inhaled dry powder formulations of fenoterol and colforsin in asthma.
    Clinical pharmacology and therapeutics, 1993, Volume: 53, Issue:1

    Topics: Administration, Inhalation; Adult; Asthma; Bronchi; Capsules; Colforsin; Double-Blind Method; Female; Fenoterol; Heart Rate; Humans; Male; Maximal Expiratory Flow Rate; Middle Aged; Potassium; Powders; Random Allocation

1993

Other Studies

24 other study(ies) available for colforsin and Asthma

ArticleYear
α and β catalytic subunits of cAMP-dependent protein kinase regulate formoterol-induced inflammatory gene expression changes in human bronchial epithelial cells.
    British journal of pharmacology, 2022, Volume: 179, Issue:18

    Topics: Adrenergic beta-2 Receptor Agonists; Asthma; beta-Arrestins; Catalytic Domain; Colforsin; Cyclic AMP-Dependent Protein Kinases; Epithelial Cells; Ethanolamines; Formoterol Fumarate; Gene Expression; Humans; Tumor Necrosis Factor-alpha

2022
Inhibition of airway remodeling and inflammation by isoforskolin in PDGF-induced rat ASMCs and OVA-induced rat asthma model.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 95

    Topics: Airway Remodeling; Animals; Anti-Asthmatic Agents; Asthma; Colforsin; Disease Models, Animal; Dose-Response Relationship, Drug; Inflammation; Male; Mice; Myocytes, Smooth Muscle; Ovalbumin; Platelet-Derived Growth Factor; Random Allocation; Rats; Rats, Sprague-Dawley

2017
Two for one: cyclic AMP mediates the anti-inflammatory and anti-spasmodic properties of the non-anesthetic lidocaine analog JMF2-1.
    European journal of pharmacology, 2012, Apr-05, Volume: 680, Issue:1-3

    Topics: Adenylyl Cyclases; Animals; Anti-Inflammatory Agents; Apoptosis; Asthma; Carbachol; Caspase 8; Cell Proliferation; Cell Survival; Colforsin; Cyclic AMP; Epithelium; Guinea Pigs; Inflammation; Lidocaine; Lymph Nodes; Male; Mice; Mice, Inbred BALB C; Muscle Contraction; Myocytes, Smooth Muscle; NG-Nitroarginine Methyl Ester; Nitric Oxide; Parasympatholytics; Rats; Rats, Wistar; Respiratory System; T-Lymphocytes; Trachea

2012
Increased sensitivity of asthmatic airway smooth muscle cells to prostaglandin E2 might be mediated by increased numbers of E-prostanoid receptors.
    The Journal of allergy and clinical immunology, 2004, Volume: 113, Issue:5

    Topics: Asthma; Cell Division; Cells, Cultured; Colforsin; Dinoprostone; Epoprostenol; Humans; Lung; Muscle, Smooth; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP3 Subtype

2004
Oxidant stress stimulates Ca2+-activated chloride channels in the apical activated membrane of cultured nonciliated human nasal epithelial cells.
    American journal of physiology. Lung cellular and molecular physiology, 2005, Volume: 289, Issue:4

    Topics: Asthma; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Polarity; Cells, Cultured; Chloride Channels; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Cytoplasm; Humans; Hydroxyl Radical; Membrane Potentials; Nasal Mucosa; Oxidative Stress; Patch-Clamp Techniques

2005
Involvement of reduced sensitivity to Ca in beta-adrenergic action on airway smooth muscle.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2006, Volume: 36, Issue:2

    Topics: Adrenergic beta-Agonists; Amides; Animals; Asthma; Bucladesine; Calcium; Calcium Channel Blockers; Colforsin; Cyclic AMP Receptor Protein; Cyclic AMP-Dependent Protein Kinases; Depression, Chemical; Fura-2; Guinea Pigs; Imidazoles; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Isoproterenol; Male; Maleimides; Marine Toxins; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Myosin-Light-Chain Phosphatase; Oxazoles; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Trachea

2006
Levalbuterol inhibits human airway smooth muscle cell proliferation: therapeutic implications in the management of asthma.
    International archives of allergy and immunology, 2006, Volume: 139, Issue:3

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Asthma; Bronchodilator Agents; Cell Line; Cell Proliferation; Chromones; Colforsin; Cyclic AMP; Enzyme Inhibitors; Humans; Isoproterenol; Morpholines; Muscle, Smooth; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phospholipid Ethers; Platelet Aggregation Inhibitors; Propanolamines; Retinoblastoma Protein

2006
Corticosteroids and beta2 agonists differentially regulate rhinovirus-induced interleukin-6 via distinct Cis-acting elements.
    The Journal of biological chemistry, 2007, May-25, Volume: 282, Issue:21

    Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Albuterol; Androstadienes; Anti-Inflammatory Agents; Asthma; Bronchi; CCAAT-Enhancer-Binding Proteins; Colforsin; Cyclic AMP; Epithelial Cells; Fluticasone; Gene Expression Regulation; HeLa Cells; Humans; Interleukin-1beta; Interleukin-6; NF-kappa B; Phosphodiesterase Inhibitors; Picornaviridae Infections; Pulmonary Disease, Chronic Obstructive; Response Elements; Rhinovirus; Rolipram; Salmeterol Xinafoate; Transcription, Genetic

2007
Prolonged heterologous beta2-adrenoceptor desensitization promotes proasthmatic airway smooth muscle function via PKA/ERK1/2-mediated phosphodiesterase-4 induction.
    American journal of physiology. Lung cellular and molecular physiology, 2008, Volume: 294, Issue:6

    Topics: Adrenergic beta-2 Receptor Agonists; Animals; Asthma; Butadienes; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 4; Dinoprostone; Enzyme Induction; Humans; Isoquinolines; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle Contraction; Muscle Relaxation; Nitriles; Pertussis Toxin; Phosphodiesterase 4 Inhibitors; Rabbits; Receptors, G-Protein-Coupled; Rolipram; Signal Transduction; Sulfonamides; Trachea

2008
Effect of forskolin on methacholine-induced bronchoconstriction in extrinsic asthmatics.
    Lancet (London, England), 1984, Jul-21, Volume: 2, Issue:8395

    Topics: Adolescent; Adult; Airway Resistance; Asthma; Colforsin; Diterpenes; Forced Expiratory Volume; Humans; Male; Middle Aged

1984
Activation of cAMP-dependent pathways in human airway smooth muscle cells inhibits TNF-alpha-induced ICAM-1 and VCAM-1 expression and T lymphocyte adhesion.
    Journal of immunology (Baltimore, Md. : 1950), 1995, Mar-01, Volume: 154, Issue:5

    Topics: Asthma; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; GTP-Binding Proteins; Humans; Intercellular Adhesion Molecule-1; Isoproterenol; Lymphocyte Activation; Muscle, Smooth; T-Lymphocytes; Trachea; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1

1995
Nonspecific refractoriness to adenylyl cyclase stimulation in alveolar macrophages from infants with recurrent bronchiolitis.
    The Journal of allergy and clinical immunology, 1994, Volume: 93, Issue:5

    Topics: Adenylyl Cyclases; Albuterol; Asthma; Bronchiolitis; Bronchoalveolar Lavage Fluid; Bronchoscopy; Colforsin; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Female; Humans; Infant; Macrophages, Alveolar; Male; Recurrence; Respiratory Sounds; Stimulation, Chemical

1994
Sensitization decreases relaxation in human isolated airways.
    The American review of respiratory disease, 1993, Volume: 148, Issue:1

    Topics: Asthma; Benzopyrans; Bronchi; Bucladesine; Carbachol; Colforsin; Cromakalim; Dose-Response Relationship, Drug; Humans; Immunization, Passive; Immunoglobulin E; In Vitro Techniques; Isoproterenol; Muscle Relaxation; Muscle Tonus; Parasympatholytics; Pyrroles; Verapamil

1993
Autocrine role of interleukin 1beta in altered responsiveness of atopic asthmatic sensitized airway smooth muscle.
    The Journal of clinical investigation, 1997, Jan-01, Volume: 99, Issue:1

    Topics: Acetylcholine; Adenylyl Cyclases; Animals; Antibodies, Blocking; Asthma; Blotting, Northern; Cells, Cultured; Colforsin; Culture Techniques; Dinoprostone; Humans; Immunization, Passive; Interleukin-1; Isoproterenol; Muscle, Smooth; Polymerase Chain Reaction; Rabbits; Radioimmunoassay; Rats; Receptors, Interleukin-1; RNA, Messenger; Trachea

1997
Cyclic AMP-elevating agents inhibit mite-antigen-induced IL-4 and IL-13 release from basophil-enriched leukocyte preparation.
    International archives of allergy and immunology, 1997, Volume: 114, Issue:4

    Topics: Animals; Antigens; Asthma; Basophils; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Dexamethasone; Female; Humans; Hypersensitivity, Immediate; Interleukin-13; Interleukin-4; Interleukins; Male; Mites; Phosphodiesterase Inhibitors

1997
Phosphodiesterase and cyclic adenosine monophosphate-dependent inhibition of T-lymphocyte chemotaxis.
    The European respiratory journal, 2000, Volume: 15, Issue:2

    Topics: Albuterol; Asthma; Bucladesine; Chemotaxis, Leukocyte; Colforsin; Cyclic AMP; Humans; Interleukin-8; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Platelet Activating Factor; Rolipram; T-Lymphocytes; Theophylline

2000
Mechanism of extracellular signal-regulated kinase (ERK)-1 and ERK-2 activation by vanadium pentoxide in rat pulmonary myofibroblasts.
    American journal of respiratory cell and molecular biology, 2000, Volume: 22, Issue:5

    Topics: Acetylcysteine; Animals; Asthma; Bronchitis; Carbon; Coal Ash; Colforsin; Enzyme Activation; ErbB Receptors; Fibroblasts; Flavonoids; Intracellular Signaling Peptides and Proteins; Lung; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Particulate Matter; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Quinazolines; Rats; Titanium; Tyrphostins; Vanadium Compounds

2000
Synergistic inhibition by beta(2)-agonists and corticosteroids on tumor necrosis factor-alpha-induced interleukin-8 release from cultured human airway smooth-muscle cells.
    American journal of respiratory cell and molecular biology, 2000, Volume: 23, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Androstadienes; Asthma; Cell Survival; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dexamethasone; Drug Synergism; Fluticasone; Humans; Interleukin-8; Muscle, Smooth; Phosphodiesterase Inhibitors; Propanolamines; Receptors, Adrenergic, beta-2; Respiratory System; Rolipram; Salmeterol Xinafoate; Trachea; Tumor Necrosis Factor-alpha

2000
Differential effect of phosphodiesterase inhibitors on IL-13 release from peripheral blood mononuclear cells.
    Clinical and experimental immunology, 2001, Volume: 126, Issue:3

    Topics: Adult; Asthma; Cilostazol; Colforsin; Cyclic AMP; Dexamethasone; Humans; In Vitro Techniques; Interleukin-13; Kinetics; Leukocytes, Mononuclear; Male; Phosphodiesterase Inhibitors; Phytohemagglutinins; Rolipram; Tetrazoles; Theophylline

2001
Interleukin-13 induces a hypersecretory ion transport phenotype in human bronchial epithelial cells.
    American journal of physiology. Lung cellular and molecular physiology, 2002, Volume: 282, Issue:2

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Asthma; Body Fluids; Bronchi; Bumetanide; Calcium; Cell Count; Cells, Cultured; Chlorides; Colforsin; Diuretics; Epithelial Cells; Goblet Cells; Humans; Interleukin-13; Interleukin-4; Ionomycin; Ionophores; Membrane Potentials; Phenotype; Potassium; Respiratory Mucosa; Uridine Triphosphate

2002
Hormone-sensitive adenylate cyclase system in lymphocytes from asthmatic patients: possible defects at the postreceptor sites.
    Annals of allergy, 1991, Volume: 66, Issue:2

    Topics: Adenylyl Cyclases; Adolescent; Adult; Aged; Asthma; Colforsin; Cyclic AMP; Female; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; Isoproterenol; Lymphocytes; Male; Middle Aged; Receptors, Adrenergic, beta

1991
Effects of anti-asthma drugs on PAF-induced death in mice.
    Prostaglandins, 1988, Volume: 36, Issue:6

    Topics: Adrenalectomy; Adrenergic beta-Agonists; Animals; Asthma; Bronchodilator Agents; Colforsin; Dexamethasone; Dose-Response Relationship, Drug; Histamine Antagonists; Mice; Models, Biological; Nedocromil; Phthalazines; Platelet Activating Factor; Pyridazines; Quinolones; Serotonin Antagonists

1988
The role of phospholipase in reduced beta-adrenergic responsiveness in experimental asthma.
    The American review of respiratory disease, 1986, Volume: 133, Issue:3

    Topics: Adenylyl Cyclases; Animals; Asthma; Colforsin; Cyclic AMP; Fatty Acids; Guinea Pigs; Isoproterenol; Lung; Male; Membrane Proteins; Phospholipases; Phospholipases A; Phospholipids; Receptors, Adrenergic, beta

1986
Influence of the epithelium on responsiveness of guinea-pig isolated trachea to contractile and relaxant agonists.
    British journal of pharmacology, 1986, Volume: 87, Issue:1

    Topics: Acetylcholine; Animals; Asthma; Autoradiography; Carbachol; Cimetidine; Colforsin; Dose-Response Relationship, Drug; Epithelium; Female; Guinea Pigs; Histamine; In Vitro Techniques; Iodocyanopindolol; Isoproterenol; Kinetics; Male; Muscle Contraction; Nitroglycerin; Pindolol; Potassium; Receptors, Adrenergic, beta; Theophylline; Trachea

1986