colforsin has been researched along with Alloxan Diabetes in 62 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (14.52) | 18.7374 |
| 1990's | 32 (51.61) | 18.2507 |
| 2000's | 12 (19.35) | 29.6817 |
| 2010's | 7 (11.29) | 24.3611 |
| 2020's | 2 (3.23) | 2.80 |
| Authors | Studies |
|---|---|
| Gholami Farashah, MS; Mohammadnejad, D; Naghibi, M; Soleimani Rad, J; Tayefi Nasrabadi, H | 1 |
| Gu, Z; Wang, J; Wang, Z; Yu, J; Zeng, Y; Zhang, Y | 1 |
| Chen, WL; Ke, PX; Yuan, X; Zhang, GP; Zhang, GS; Zhang, X | 1 |
| Shi, K; Shi, L; Xiong, B; You, ZP; Zhang, YL | 1 |
| Huerta, M; Mancilla, E; Ríos-Silva, M; Sánchez-Pastor, E; Trujillo, X; Trujillo-Hernández, B; Urzúa, Z | 1 |
| Blake, CB; Smith, BN | 1 |
| Amour, J; Birenbaum, A; Heymes, C; Loyer, X; Michelet, P; Riou, B | 1 |
| Hanada, M; Ishii, K; Mori, A; Nakahara, T; Saigo, O | 1 |
| Abitbol, G; Brutman-Barazani, T; Kerem, Z; Rosenzweig, T; Sampson, SR; Smirin, P; Taler, D | 1 |
| Ehlert, FJ; Matsui, M; Ostrom, RS; Pak, KJ | 1 |
| Campochiaro, PA; Gong, YY; Hackett, SF; Iwase, T; Lu, L; Seidel, CP; Stevens, RK; Wang, X | 1 |
| Drucker, DJ; Halban, PA; Hansotia, T; Li, Y; Ris, F; Yusta, B | 1 |
| Ishii, K; Kubota, Y; Maruko, T; Mitani, A; Nakahara, T; Sakamoto, K | 1 |
| Kamata, K; Kobayashi, T; Matsumoto, T; Wakabayashi, K | 1 |
| Bubolz, AH; Li, H; Liu, Y; Wu, Q | 1 |
| Chai, Q; Chen, L; Liu, Z | 1 |
| Bondareva, VM; Guryanov, IA; Kuznetsova, LA; Pertseva, MN; Plesneva, SA; Shpakov, AO; Vlasov, GP | 1 |
| Bubolz, AH; Gutterman, DD; Larsen, BT; Liu, Y; Wu, Q | 1 |
| Hsu, PY; Kotin, RM; Yang, YW | 1 |
| Chronister, RB; Palmer, GC; Wilson, GL | 1 |
| Tarui, S | 1 |
| Berti-Mattera, LN; Douglas, JG; Goraya, TY; Wilkins, P; Zhou, J | 1 |
| Eichberg, J; Rowe-Rendleman, CL | 1 |
| Brown, L; Lues, I; Nankervis, R | 1 |
| Onaya, T; Shindo, H; Tawata, M | 1 |
| Otomo, S; Tsuchida, K; Watajima, H | 1 |
| Mayhan, WG | 2 |
| Chess-Williams, R; Otter, DJ | 1 |
| Marubashi, S; Saito, K; Sasaki, H; Sato, N; Takahashi, K; Wakasugi, K; Yamatani, K | 1 |
| Borghini, I; Geering, K; Gjinovci, A; Pralong, WF; Wollheim, CB | 1 |
| Austin, C; Chess-Williams, R | 1 |
| Aguado, F; Bajo, AM; Guijarro, LG; Juarranz, MG; Prieto, JC; Rodriguez-Henche, N; Rodriguez-Pena, MS | 1 |
| Hall, JL; Hamilton, CD; Roth, DA; Stanley, WC; White, CD | 1 |
| Batink, HD; Beenen, OH; Pfaffendorf, M; van Zwieten, PA | 1 |
| Carmena, MJ; Carrero, I; Clemente, C; Prieto, JC; Solano, RM | 1 |
| Collins, S; Gettys, TW; Taylor, IL; Watson, PM | 1 |
| Bouchard, JF; Dumont, EC; Lamontagne, D | 1 |
| Gohshi, A; Honda, K; Kamiya, H; Motoya, T; Takano, Y; Tominaga, K; Yamada, K | 1 |
| Dore, JJ; Hall, JL; Hamilton, CD; Pizzurro, RD; Roth, DA; Stanley, WC | 1 |
| Aoki, M; Hayashi, S; Jo, N; Kaneda, Y; Matsumoto, K; Morishita, R; Nakamura, T; Ogihara, T | 1 |
| Kamata, K; Kasuya, Y; Miyata, N; Otomo, S; Tsuchida, K; Yamaura, H | 1 |
| Murray, DC; Sharp, PA; Thomas, JH | 1 |
| Anderson, LC; Bevan, CA | 1 |
| Kirkham, DM; Murphy, GJ; Young, P | 1 |
| Cullen, B; Grodsky, GM; Ma, YH; Sarvetnick, N | 1 |
| Gross, R; Hillaire-Buys, D; Loubatières-Mariani, MM; Ribes, G | 1 |
| Chatzipanteli, K; Orford, M; Saggerson, D; Shepherd, J | 1 |
| Armbrecht, HJ; Siegel, NA; Wongsurawat, N | 1 |
| Brown, LA | 1 |
| Austin, CE; Chess-Williams, R | 1 |
| Allard, WJ; Saperstein, R; Slater, EE; Strout, HV; Vicario, PP | 1 |
| Houslay, MD; Palmer, TM | 1 |
| Houslay, MD; Milligan, G; Strassheim, D | 1 |
| Bushfield, M; Johnson, RA; Shoshani, I | 1 |
| Bala, RM; Eatock, BA; Sheppard, MS | 1 |
| Blackmore, PF; Exton, JH; Johnson, EH; Krone, PK; Lynch, CJ; Wange, RL | 1 |
| Kamata, K; Kasuya, Y; Miyata, N | 1 |
| Gawler, DJ; Houslay, MD; Milligan, G; Wilson, A | 1 |
| Mooradian, AD; Morley, JE; Scarpace, PJ | 1 |
| Ramanadham, S; Tenner, TE | 1 |
| Anand-Srivastava, MB; Srivastava, AK | 1 |
62 other study(ies) available for colforsin and Alloxan Diabetes
| Article | Year |
|---|---|
The effects of metformin and forskolin on sperm quality parameters and sexual hormones in type II diabetic male rats.
Topics: Animals; bcl-2-Associated X Protein; Blood Glucose; Colforsin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Male; Metformin; Proto-Oncogene Proteins c-bcl-2; Rats; Semen; Sperm Motility; Spermatozoa; Testosterone | 2022 |
A forskolin-conjugated insulin analog targeting endogenous glucose-transporter for glucose-responsive insulin delivery.
Topics: Animals; Colforsin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Drug Delivery Systems; Glucose; Glucose Tolerance Test; Glucose Transport Proteins, Facilitative; Hypoglycemic Agents; Injections, Subcutaneous; Insulin; Mice | 2019 |
Forskolin Protected against Streptozotocin-Induced Diabetic Cardiomyopathy via Inhibition of Oxidative Stress and Cardiac Fibrosis in Mice.
Topics: Actins; Animals; Apoptosis; Colforsin; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Heart; Humans; Mice; Myocardium; Oxidative Stress; Transforming Growth Factor beta | 2021 |
Forskolin attenuates retinal inflammation in diabetic mice.
Topics: Animals; Blood Glucose; Body Weight; Colforsin; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Disease Models, Animal; Glucose Transporter Type 1; Inflammation Mediators; Leukostasis; Male; Mice; Retinal Vessels; Retinitis | 2018 |
Effect of chronic administration of forskolin on glycemia and oxidative stress in rats with and without experimental diabetes.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Blood Glucose; Colforsin; Deoxyguanosine; Diabetes Mellitus, Experimental; Humans; Male; Oxidative Stress; Rats | 2014 |
cAMP-dependent insulin modulation of synaptic inhibition in neurons of the dorsal motor nucleus of the vagus is altered in diabetic mice.
Topics: Animals; Brain Stem; Brefeldin A; Colforsin; Cyclic AMP; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Electric Stimulation; Female; gamma-Aminobutyric Acid; Glucose Transporter Type 4; Golgi Apparatus; Indinavir; Inhibitory Postsynaptic Potentials; Insulin; Male; Mice; Neural Inhibition; Protein Transport; Synaptic Transmission; Vagus Nerve | 2014 |
Preservation of the positive lusitropic effect of beta-adrenoceptors stimulation in diabetic cardiomyopathy.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cardiomyopathies; Colforsin; Diabetes Complications; Diabetes Mellitus, Experimental; Echocardiography; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Papillary Muscles; Phentolamine; Pindolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta | 2008 |
Hyperglycemia accelerates impairment of vasodilator responses to acetylcholine of retinal blood vessels in rats.
Topics: Acetylcholine; Adenosine; Animals; Arterioles; Blood Pressure; Colforsin; Diabetes Mellitus, Experimental; Endothelium, Vascular; Hydroxylamines; Hyperglycemia; Immunohistochemistry; Male; Nitro Compounds; Rats; Rats, Wistar; Retinal Vessels; Severity of Illness Index; Streptozocin; Vasodilation; Vasodilator Agents | 2009 |
Sarcopoterium spinosum extract as an antidiabetic agent: in vitro and in vivo study.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Biological Transport; Catechin; Cell Line; Cell Survival; Colforsin; Diabetes Mellitus, Experimental; Disease Progression; Glucose; Glucose Tolerance Test; Glycogen; Hepatocytes; Hypoglycemic Agents; Insulin; Insulin Secretion; Lipolysis; Male; Mice; Mice, Inbred Strains; Muscle Fibers, Skeletal; Phosphorylation; Phytotherapy; Plant Extracts; Plant Roots; Rosaceae | 2010 |
Impaired M3 and enhanced M2 muscarinic receptor contractile function in a streptozotocin model of mouse diabetic urinary bladder.
Topics: Animals; Colforsin; Diabetes Mellitus, Experimental; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscarinic Agonists; Muscle Contraction; Oxotremorine; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Streptozocin; Time Factors; Urinary Bladder | 2010 |
Suppression of GLUT1; a new strategy to prevent diabetic complications.
Topics: Animals; beta-Crystallin B Chain; Blood Glucose; Brain; Brain Chemistry; Colforsin; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Erythrocytes; Gene Knockdown Techniques; Gene Silencing; Genistein; Glucose; Glucose Transporter Type 1; Male; Mice; Protein Kinase Inhibitors; Retina; Superoxides; Vascular Endothelial Growth Factor A | 2013 |
Glucagon-like peptide-1 receptor signaling modulates beta cell apoptosis.
Topics: Animals; Apoptosis; beta Catenin; Blood Glucose; Cell Line; Cell Survival; Colforsin; Cricetinae; Cycloheximide; Cytokines; Cytoskeletal Proteins; Diabetes Mellitus, Experimental; Exenatide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucose Tolerance Test; In Situ Nick-End Labeling; Insulin; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Peptides; Protein Precursors; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Receptors, Glucagon; Signal Transduction; Streptozocin; Trans-Activators; Venoms | 2003 |
Augmentation of rat urinary bladder relaxation mediated by beta1-adrenoceptors in experimental diabetes.
Topics: Adrenergic beta-Agonists; Animals; Colforsin; Diabetes Mellitus, Experimental; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Rats; Rats, Wistar; Receptors, Adrenergic, beta-1; Urinary Bladder | 2003 |
Functional changes in adenylyl cyclases and associated decreases in relaxation responses in mesenteric arteries from diabetic rats.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Blood Glucose; Body Weight; Colforsin; Cyclic AMP; Diabetes Mellitus, Experimental; Immunoenzyme Techniques; Insulin; Isometric Contraction; Isoproterenol; Male; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2005 |
Enhanced oxidative stress impairs cAMP-mediated dilation by reducing Kv channel function in small coronary arteries of diabetic rats.
Topics: 4-Aminopyridine; Animals; Antioxidants; Blood Glucose; Body Weight; Colforsin; Coronary Vessels; Cyclic AMP; Diabetes Mellitus, Experimental; Male; Microscopy, Video; Muscle Contraction; NADPH Oxidases; Oxidative Stress; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence; Superoxides; Vasodilation | 2005 |
Effects of streptozotocin-induced diabetes on Kv channels in rat small coronary smooth muscle cells.
Topics: 4-Aminopyridine; Animals; Colforsin; Coronary Vessels; Diabetes Mellitus, Experimental; Female; Isoproterenol; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Potassium Channels, Voltage-Gated; Rats; Rats, Wistar; Streptozocin; Vasodilation | 2005 |
Decrease in functional activity of G-proteins hormone-sensitive adenylate cyclase signaling system, during experimental type II diabetes mellitus.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Bromocriptine; Cardiotonic Agents; Colforsin; Corpus Striatum; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Activation; GTP-Binding Proteins; Hormone Antagonists; Hormones; Isoproterenol; Myocardium; Peptides; Rats; Rats, Wistar; Relaxin; Serotonin; Serotonin Agents; Signal Transduction; Somatostatin | 2006 |
Ebselen reduces nitration and restores voltage-gated potassium channel function in small coronary arteries of diabetic rats.
Topics: Adenylyl Cyclases; Animals; Antioxidants; Azoles; Colforsin; Coronary Vessels; Cyclic AMP; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Activators; Isoindoles; Kv1.2 Potassium Channel; Kv1.5 Potassium Channel; Male; Membrane Potentials; Muscle, Smooth, Vascular; Organoselenium Compounds; Oxidative Stress; Peroxynitrous Acid; Potassium Channel Blockers; Protein Subunits; Rats; Rats, Sprague-Dawley; Research Design; Triterpenes; Tyrosine; Vasodilation | 2007 |
Glucose- and metabolically regulated hepatic insulin gene therapy for diabetes.
Topics: Animals; Bucladesine; Colforsin; Dependovirus; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Genetic Therapy; Glucose; Imines; Immunohistochemistry; Insulin; Insulin Secretion; Liver; Male; Mice; Mice, Inbred C57BL; Polyethylenes; Streptozocin; Theophylline | 2008 |
Streptozotocin-induced diabetes produces alterations in adenylate cyclase in rat cerebrum, cerebral microvessels and retina.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Brain; Capillaries; Cerebral Cortex; Colforsin; Diabetes Mellitus, Experimental; Diterpenes; Dopamine; Enzyme Activation; Guanosine Pentaphosphate; Guanylate Cyclase; Male; Rats; Retina | 1983 |
[Forskolin, cyclic AMP and hormone regulation].
Topics: Adrenal Glands; Animals; Cell Membrane Permeability; Colforsin; Corticosterone; Cyclic AMP; Deoxyglucose; Diabetes Mellitus, Experimental; Diterpenes; Glucagon; In Vitro Techniques; Liver; Phosphofructokinase-1; Phosphotransferases; Rats | 1983 |
Signal transduction alterations in peripheral nerves from streptozotocin-induced diabetic rats.
Topics: Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Diabetes Mellitus, Experimental; Disease Models, Animal; Male; Peripheral Nervous System; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Signal Transduction; Streptozocin | 1995 |
P0 phosphorylation in nerves from normal and diabetic rats: role of protein kinase C and turnover of phosphate groups.
Topics: Animals; Basal Metabolism; Colforsin; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Down-Regulation; Drug Antagonism; Male; Myelin P0 Protein; Myelin Proteins; Phorbol 12,13-Dibutyrate; Phosphates; Phosphorylation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Reference Values; Sciatic Nerve | 1994 |
Calcium sensitization as a positive inotropic mechanism in diseased rat and human heart.
Topics: Animals; Calcium; Cardiotonic Agents; Colforsin; Diabetes Mellitus, Experimental; Drug Synergism; Female; Heart Diseases; Humans; Male; Muscle, Smooth, Vascular; Myocardial Contraction; Phosphodiesterase Inhibitors; Quinolines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Species Specificity; Stereoisomerism; Thiadiazines | 1994 |
Reduction of cyclic AMP in the sciatic nerve of rats made diabetic with streptozotocin and the mechanism involved.
Topics: Adenylyl Cyclases; Animals; Bucladesine; Colforsin; Culture Techniques; Cyclic AMP; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Glucose; Iloprost; Male; Motor Neurons; Neural Conduction; Rats; Rats, Wistar; Sciatic Nerve | 1993 |
Calcium current in rat diabetic ventricular myocytes.
Topics: Action Potentials; Animals; Blood Glucose; Body Weight; Calcium Channels; Colforsin; Cyclic AMP; Diabetes Mellitus, Experimental; Electric Conductivity; Guanosine 5'-O-(3-Thiotriphosphate); Heart; Heart Ventricles; Isoproterenol; Kinetics; Male; Myocardial Contraction; Rats; Rats, Wistar | 1994 |
Effect of diabetes mellitus on responses of the rat basilar artery to activation of beta-adrenergic receptors.
Topics: Adrenergic beta-Agonists; Animals; Basilar Artery; Colforsin; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Isoproterenol; Norepinephrine; Rats; Receptors, Adrenergic, beta; Reference Values; Vasodilation | 1994 |
The effects of aldose reductase inhibition with ponalrestat on changes in vascular function in streptozotocin diabetic rats.
Topics: Aldehyde Reductase; Animals; Aorta, Thoracic; Carbachol; Colforsin; Diabetes Mellitus, Experimental; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Phenylephrine; Phthalazines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1 | 1994 |
Catecholamine-induced cAMP response in streptozotocin-induced diabetic rat liver.
Topics: Adipose Tissue; Animals; Colforsin; Cyclic AMP; Diabetes Mellitus, Experimental; Emaciation; Epinephrine; Glucagon; Glucose; Insulin; Isoproterenol; Lactates; Lactic Acid; Liver; Male; Oxymetazoline; Phenylephrine; Propranolol; Pyruvates; Pyruvic Acid; Rats; Receptors, Adrenergic, beta; Streptozocin | 1994 |
In vivo phosphorylation of the Na,K-ATPase alpha subunit in sciatic nerves of control and diabetic rats: effects of protein kinase modulators.
Topics: Alkaloids; Animals; Blotting, Western; Calcium; Colforsin; Diabetes Mellitus, Experimental; Electrophoresis, Polyacrylamide Gel; Isoenzymes; Kinetics; Macromolecular Substances; Male; Membrane Proteins; Phosphoproteins; Phosphorylation; Protein Kinase C; Rats; Rats, Wistar; Reference Values; Sciatic Nerve; Sodium-Potassium-Exchanging ATPase; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
The in-vitro effects of insulin and the effects of acute fasting on cardiac beta-adrenoceptor responses in the short-term streptozotocin-diabetic rat.
Topics: Analysis of Variance; Animals; Blood Glucose; Colforsin; Diabetes Mellitus, Experimental; Dihydroalprenolol; Fasting; Female; Heart; In Vitro Techniques; Insulin; Isoproterenol; Myocardium; Papillary Muscles; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Streptozocin | 1994 |
Analysis of vasoactive intestinal peptide receptors and the G protein regulation of adenylyl cyclase in seminal vesicle membranes from streptozotocin-diabetic rats.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Colforsin; Diabetes Mellitus, Experimental; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Male; Rats; Rats, Wistar; Receptors, Vasoactive Intestinal Peptide; Seminal Vesicles; Signal Transduction; Streptozocin; Vasoactive Intestinal Peptide | 1994 |
Responses of cerebral arterioles to activation of beta-adrenergic receptors during diabetes mellitus.
Topics: Animals; Arginine; Arterioles; Cerebrovascular Circulation; Colforsin; Diabetes Mellitus, Experimental; Isoproterenol; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Pia Mater; Rats; Receptors, Adrenergic, beta; Vasodilation | 1994 |
Adrenergic desensitization in left ventricle from streptozotocin diabetic swine.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aluminum; Animals; Blood Glucose; Colforsin; Cyclic AMP; Cytosol; Diabetes Mellitus, Experimental; Fluorides; GTP-Binding Proteins; Guanosine Triphosphate; Heart Ventricles; Insulin; Isoproterenol; Receptors, Adrenergic, beta; Sarcolemma; Signal Transduction; Streptozocin; Swine; Swine, Miniature | 1995 |
Beta-andrenoceptors in the hearts of diabetic-hypertensive rats: radioligand binding and functional experiments.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Blood Glucose; Blood Pressure; Body Weight; Cardiotonic Agents; Colforsin; Diabetes Mellitus, Experimental; Dobutamine; Heart; Heart Rate; Hypertension; Myocardial Contraction; Myocardium; Organ Size; Radioligand Assay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta | 1997 |
G-proteins and beta-adrenergic stimulation of adenylate cyclase activity in the diabetic rat prostate.
Topics: Acetates; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Colforsin; Diabetes Mellitus, Experimental; GTP-Binding Proteins; Immunoblotting; Insulin; Isoproterenol; Lipid Metabolism; Male; Prostate; Rats; Rats, Wistar | 1997 |
RU-486 (Mifepristone) ameliorates diabetes but does not correct deficient beta-adrenergic signalling in adipocytes from mature C57BL/6J-ob/ob mice.
Topics: Adenylyl Cyclases; Adipose Tissue; Adrenergic beta-Agonists; Animals; Blood Glucose; Blotting, Northern; Blotting, Western; Colforsin; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Activation; Ethanolamines; Glucose Transporter Type 4; GTP-Binding Protein alpha Subunits, Gs; Hormone Antagonists; Insulin; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Mifepristone; Monosaccharide Transport Proteins; Muscle Proteins; Phenotype; Receptors, Adrenergic, beta; Receptors, Glucocorticoid; Signal Transduction | 1997 |
[Decrease of vascular response to iloprost in diabetic rats].
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Aorta, Thoracic; Colforsin; Coronary Vessels; Cromakalim; Diabetes Mellitus, Experimental; Iloprost; Potassium Channels; Rats; Rats, Sprague-Dawley; Streptozocin; Vascular Resistance; Vasodilation; Vasodilator Agents | 1997 |
Changes in adrenocorticotropic hormone (ACTH) release from the cultured anterior pituitary cells of streptozotocin-induced diabetic rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenocorticotropic Hormone; Animals; Cells, Cultured; Colforsin; Corticotropin-Releasing Hormone; Diabetes Mellitus, Experimental; Male; Pituitary Gland, Anterior; Rats; Rats, Wistar; Streptozocin | 1998 |
Diabetes reduces right atrial beta-adrenergic signaling but not agonist stimulation of heart rate in swine.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Colforsin; Diabetes Mellitus, Experimental; Female; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Heart Atria; Heart Rate; Isoproterenol; Receptors, Adrenergic, beta; Signal Transduction; Swine; Swine, Miniature | 2001 |
Inhibition of neointimal formation after balloon injury by cilostazol, accompanied by improvement of endothelial dysfunction and induction of hepatocyte growth factor in rat diabetes model.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Animals; Aorta; Arteries; Carotid Arteries; Catheterization; Cell Death; Cell Hypoxia; Cells, Cultured; Cilostazol; Coculture Techniques; Colforsin; Cyclic AMP; Diabetes Mellitus, Experimental; Endothelium, Vascular; Hepatocyte Growth Factor; Humans; Kinetics; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Rats; Rats, Sprague-Dawley; Tetrazoles | 2001 |
Changes in responsiveness of the aorta to vasorelaxant agents in genetically diabetic rats: a study in WBN/Kob rats.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Colforsin; Cromakalim; Diabetes Mellitus, Experimental; Endothelium, Vascular; Isoproterenol; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Pyrroles; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Vasodilator Agents | 1992 |
Diabetes alters the cyclic AMP response of isolated renal glomeruli.
Topics: Animals; Colforsin; Cyclic AMP; Diabetes Mellitus, Experimental; Female; In Vitro Techniques; Insulin; Kidney Glomerulus; Rats; Rats, Wistar; Reference Values | 1992 |
Effects of streptozotocin diabetes on amylase release and cAMP accumulation in rat parotid acinar cells.
Topics: Amylases; Animals; Colforsin; Cyclic AMP; Diabetes Mellitus, Experimental; Insulin; Male; Norepinephrine; Parotid Gland; Rats; Rats, Inbred Strains; Thyroxine | 1992 |
Demonstration of inhibitory guanine nucleotide regulatory protein (Gi) function in liver and hepatocyte membranes from streptozotocin-treated rats.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cell Membrane; Cells, Cultured; Colforsin; Diabetes Mellitus, Experimental; Enzyme Activation; GTP-Binding Proteins; Liver; Male; Rats; Rats, Inbred Strains; Streptozocin; Virulence Factors, Bordetella | 1992 |
Effect on insulin production sorting and secretion by major histocompatibility complex class II gene expression in the pancreatic beta-cell of transgenic mice.
Topics: Animals; Carbachol; Colforsin; Diabetes Mellitus, Experimental; Gene Expression; Genes, MHC Class II; Glucose; Histocompatibility Antigens Class II; Insulin; Insulin Secretion; Leucine; Male; Mice; Mice, Inbred BALB C; Mice, Transgenic; Pancreas; Proinsulin | 1992 |
Diabetes alters the responses of glucagon secreting cells and vascular bed to isoprenaline and forskolin in vitro in rat pancreas.
Topics: Adenylyl Cyclases; Animals; Blood Flow Velocity; Colforsin; Diabetes Mellitus, Experimental; Glucagon; Insulin; Isoproterenol; Kinetics; Male; Pancreas; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasodilation | 1991 |
Diabetes decreases sensitivity of adipocyte lipolysis to inhibition by Gi-linked receptor agonists.
Topics: Adipose Tissue; Animals; Cell Membrane; Colforsin; Diabetes Mellitus, Experimental; Dinoprostone; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Immunoblotting; Lipolysis; Male; Niacin; Norepinephrine; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Xanthines | 1991 |
Effects of diabetes mellitus on parathyroid hormone-stimulated protein kinase activity, ferredoxin phosphorylation, and renal 1,25-dihydroxyvitamin D production.
Topics: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; Animals; Calcitriol; Colforsin; Diabetes Mellitus, Experimental; Ferredoxins; In Vitro Techniques; Kidney; Male; Parathyroid Hormone; Phosphorylation; Protein Kinases; Rats; Rats, Inbred F344; Streptozocin | 1991 |
Influence of streptozotocin-induced diabetes on adenylate cyclase activity in cultured type II pneumocytes.
Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Deoxyglucose; Diabetes Mellitus, Experimental; Guanosine Triphosphate; Insulin; Isoproterenol; Lung; Pulmonary Surfactants; Rats; Rats, Inbred Strains; Receptor, Insulin; Sodium Fluoride; Streptozocin | 1991 |
Diabetes-induced changes in cardiac beta-adrenoceptor responsiveness: effects of aldose reductase inhibition with ponalrestat.
Topics: Aldehyde Reductase; Animals; Calcium; Colforsin; Diabetes Mellitus, Experimental; Dihydroalprenolol; Female; Heart; In Vitro Techniques; Isoproterenol; Myocardium; Phthalazines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1991 |
The function but not the expression of rat liver inhibitory guanine nucleotide binding protein is altered in streptozotocin-induced diabetes.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Antibody Specificity; Cell Membrane; Clonidine; Colforsin; Diabetes Mellitus, Experimental; GTP-Binding Proteins; Immunoblotting; Liver; Male; Molecular Sequence Data; Molecular Weight; Rats | 1991 |
Determination of G-protein levels, ADP-ribosylation by cholera and pertussis toxins and the regulation of adenylyl cyclase activity in liver plasma membranes from lean and genetically diabetic (db/db) mice.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Blotting, Western; Cell Membrane; Cholera Toxin; Colforsin; Diabetes Mellitus, Experimental; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Liver; Male; Mice; Mice, Inbred C57BL; Pertussis Toxin; Virulence Factors, Bordetella | 1991 |
Diabetes abolishes the GTP-dependent, but not the receptor-dependent inhibitory function of the inhibitory guanine-nucleotide-binding regulatory protein (Gi) on adipocyte adenylate cyclase activity.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Blotting, Western; Cell Membrane; Colforsin; Diabetes Mellitus, Experimental; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Niacin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Purinergic | 1990 |
Tissue levels, source, and regulation of 3'-AMP: an intracellular inhibitor of adenylyl cyclases.
Topics: Adenosine Monophosphate; Adenylyl Cyclase Inhibitors; Animals; Colforsin; Cyclic AMP; Diabetes Mellitus, Experimental; Manganese; Rats; RNA, Messenger | 1990 |
Altered release of growth hormone from dispersed adenohypophysial cells of streptozotocin diabetic rats. II. Effects of a phorbol ester and secretagogues which increase cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Growth Hormone; Growth Hormone-Releasing Hormone; Male; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Somatostatin; Tetradecanoylphorbol Acetate | 1989 |
Guanine nucleotide binding regulatory proteins and adenylate cyclase in livers of streptozotocin- and BB/Wor-diabetic rats. Immunodetection of Gs and Gi with antisera prepared against synthetic peptides.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Aluminum; Angiotensin II; Animals; Catalysis; Cell Line; Cell Membrane; Cholera Toxin; Colforsin; Diabetes Mellitus, Experimental; Enzyme Activation; Fluorine; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Immune Sera; Injections, Intraperitoneal; Liver; Male; Peptide Fragments; Pertussis Toxin; Rats; Rats, Inbred BB; Rats, Inbred Strains; Virulence Factors, Bordetella | 1989 |
Involvement of endothelial cells in relaxation and contraction responses of the aorta to isoproterenol in naive and streptozotocin-induced diabetic rats.
Topics: Animals; Aorta; Colforsin; Diabetes Mellitus, Experimental; Drug Interactions; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1989 |
Multiple defects occur in the guanine nucleotide regulatory protein system in liver plasma membranes of obese (fa/fa) but not lean (Fa/Fa) Zucker rats: loss of functional Gi and abnormal Gs function.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Blotting, Western; Cell Membrane; Cholera Toxin; Colforsin; Diabetes Mellitus, Experimental; Glucagon; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Insulin Resistance; Liver; Male; NAD; Obesity; Pertussis Toxin; Phosphorus Radioisotopes; Rats; Rats, Inbred Strains; Rats, Zucker; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Virulence Factors, Bordetella | 1989 |
The role of zinc status in altered cardiac adenylate cyclase activity in diabetic rats.
Topics: Adenylyl Cyclases; Animals; Colforsin; Diabetes Mellitus, Experimental; Isoproterenol; Male; Myocardium; Rats; Rats, Inbred F344; Receptors, Adrenergic, beta; Sodium Fluoride; Zinc | 1988 |
Alterations in the myocardial beta-adrenoceptor system of streptozotocin-diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Calcium; Catecholamines; Colforsin; Diabetes Mellitus, Experimental; Electric Stimulation; Glucagon; Glycated Hemoglobin; In Vitro Techniques; Isoproterenol; Male; Methoxamine; Myocardial Contraction; Myocardium; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1987 |
Streptozotocin-induced diabetes and hormone sensitivity of adenylate cyclase in rat myocardial sarcolemma, aorta and liver.
Topics: Adenylyl Cyclases; Animals; Aorta; Catecholamines; Colforsin; Corpus Striatum; Diabetes Mellitus, Experimental; Diterpenes; Glucagon; Guanosine Triphosphate; Hormones; Liver; Male; Myocardium; Rats; Rats, Inbred Strains; Sarcolemma | 1985 |