colforsin has been researched along with Adrenal Cortex Cancer in 36 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 6 (16.67) | 18.7374 |
1990's | 13 (36.11) | 18.2507 |
2000's | 12 (33.33) | 29.6817 |
2010's | 5 (13.89) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Arosio, M; Bertherat, J; Beuschlein, F; Catalano, R; Chiodini, I; Ferrero, S; Fusco, N; Giardino, E; Mantovani, G; Morelli, V; Peverelli, E; Ronchi, CL; Spada, A; Treppiedi, D; Vaczlavik, A | 1 |
Batisse-Lignier, M; Bertherat, J; Berthon, A; Djari, C; Dufour, D; Dumontet, T; Lefrançois-Martinez, AM; Martinez, A; Montanier, N; Pointud, JC; Ragazzon, B; Roucher-Boulez, F; Sahut-Barnola, I; Tauveron, I; Val, P | 1 |
Felizola, SJ; Hattangady, N; Ise, K; Kikuchi, K; Kitamura, K; Nakamura, Y; Ono, Y; Onodera, Y; Rainey, WE; Sasano, H; Satoh, F; Sugawara, A; Takase, K | 1 |
Cordova, M; Schimmer, BP | 1 |
Key, RE; Parmar, J; Rainey, WE | 1 |
Advani, A; Evans, DB; Johnson, SJ; Mason, JI; Nicol, MR; Papacleovoulou, G; Penning, TM; Quinton, R; Strachan, MW | 1 |
Auernhammer, CJ; Beuschlein, F; Johnsen, IK; Kappler, R | 1 |
Assie, G; Bertherat, J; Cazabat, L; Fierrard, H; Groussin, L; Martinez, A; Perlemoine, K; Ragazzon, B; Rizk-Rabin, M | 1 |
Kraugerud, M; Ropstad, E; Verhaegen, S; Zimmer, KE | 1 |
Nakajin, S; Watanabe, M | 1 |
Arnaldi, G; Benvenuti, S; Crescioli, C; Ferruzzi, P; Greeve, I; Luciani, P; Mannelli, M; Nesi, G; Peri, A; Serio, M; Valeri, A | 1 |
Al-Hakim, A; Albert, PR; Rui, X; Schimmer, BP; Tsao, J | 2 |
Andò, S; Aquila, S; Barzon, L; Fallo, F; Maggiolini, M; Montanaro, D; Pezzi, V; Recchia, AG; Sirianni, R | 1 |
Biernacka-Lukanty, JM; Lehmann, TP; Li, JY; Trzeciak, WH | 1 |
Schimmer, BP; Tsao, J | 1 |
Armelin, HA; Armelin, MC; Kimura, E; Sonobe, MH | 1 |
Bird, IM; Cone, RD; Mountjoy, KG; Rainey, WE | 1 |
Bird, IM; Mason, JI; Rainey, WE | 2 |
Bird, IM; Holland, OB; Mathis, JM; Rainey, WE | 1 |
Bird, IM; Hanley, NA; Mason, JI; McCarthy, JL; McGee, EA; Rainey, WE; Sawetawan, C; Wester, R | 1 |
Kwan, WK; Qiu, R; Schimmer, BP; Tsao, J | 1 |
Cobb, VJ; Mason, JI; Walker, SW; Williams, BC | 2 |
Coulombe, N; Lefebvre, A; LeHoux, JG | 1 |
Daidoh, H; Ishizuka, T; Itaya, S; Kajita, K; Miura, A; Morita, H; Mune, T; Shibata, T; Suwa, T; Yamada, K; Yasuda, K | 1 |
Lado-Abeal, J; Mrotek, JJ; Norman, RL; Stocco, DM | 1 |
Burns, CJ; Cock, MH; Gyles, SL; Jones, PM; Whitehouse, BJ | 1 |
Johansson, MK; Lund, BO; Sanderson, JT | 1 |
Mitchell, J; Northup, JK; Schimmer, BP | 1 |
Borenstein, R; Endrenyi, L; Schimmer, BP; Tsao, J | 1 |
Horiuchi, T; Itoh, S; Kanbegawa, A; Kumagae, M; Shimizu, N; Tanaka, K; Watabe, T | 1 |
Abou-Donia, MA; Duch, DS; Edelstein, MP; Nichol, CA; Viveros, OH; Woolf, JH | 1 |
Schimmer, BP; Schulz, P | 1 |
Nishikawa, T; Tamura, Y; Yoshida, A; Yoshida, S | 1 |
36 other study(ies) available for colforsin and Adrenal Cortex Cancer
Article | Year |
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Cofilin is a cAMP effector in mediating actin cytoskeleton reorganization and steroidogenesis in mouse and human adrenocortical tumor cells.
Topics: Actin Cytoskeleton; Actin Depolymerizing Factors; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Animals; Colforsin; Cyclic AMP; Humans; Hydrocortisone; Mice; Phosphorylation; RNA, Small Interfering; Steroids; Tumor Cells, Cultured; Vasodilator Agents | 2017 |
Hormonal and spatial control of SUMOylation in the human and mouse adrenal cortex.
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Animals; beta Catenin; Carney Complex; Cell Line, Tumor; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Dactinomycin; Delayed-Action Preparations; Dexamethasone; Female; Humans; Mice; Mice, Knockout; Mice, Transgenic; Neoplasm Proteins; Protein Processing, Post-Translational; Signal Transduction; Sumoylation; Wnt Signaling Pathway; Zona Fasciculata; Zona Glomerulosa | 2019 |
PCP4: a regulator of aldosterone synthesis in human adrenocortical tissues.
Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Angiotensin II; Blotting, Western; Cell Line; Colforsin; Cytochrome P-450 CYP11B2; DNA; Enzyme Assays; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Luciferases; Nerve Tissue Proteins; Plasmids; Real-Time Polymerase Chain Reaction; RNA, Small Interfering; Steroid 11-beta-Hydroxylase; Transfection | 2014 |
Corticotropin (ACTH) regulates alternative RNA splicing in Y1 mouse adrenocortical tumor cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Alternative Splicing; Animals; Base Sequence; Cell Line, Tumor; Colforsin; Exons; Humans; Mice; Molecular Sequence Data; RNA, Messenger; Second Messenger Systems; Signal Transduction; Tetradecanoylphorbol Acetate | 2015 |
Development of an adrenocorticotropin-responsive human adrenocortical carcinoma cell line.
Topics: Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Cell Line, Tumor; Child; Cholesterol Side-Chain Cleavage Enzyme; Colforsin; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Hydrocortisone; Receptor, Melanocortin, Type 2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Steroid 17-alpha-Hydroxylase | 2008 |
Estrogen biosynthesis in human H295 adrenocortical carcinoma cells.
Topics: 17-Hydroxysteroid Dehydrogenases; 3-Hydroxysteroid Dehydrogenases; Adrenal Cortex Neoplasms; Adult; Aldo-Keto Reductase Family 1 Member C3; Aromatase; Cell Line, Tumor; Colforsin; Cytochrome P-450 CYP11B2; Estrogens; Female; Humans; Hydroxyprostaglandin Dehydrogenases; Progesterone Reductase; Promoter Regions, Genetic; Steroid 11-beta-Hydroxylase; Steroid 17-alpha-Hydroxylase; Vasoactive Intestinal Peptide | 2009 |
Bone morphogenetic proteins 2 and 5 are down-regulated in adrenocortical carcinoma and modulate adrenal cell proliferation and steroidogenesis.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Aldosterone; Blotting, Western; Bone Morphogenetic Protein 2; Bone Morphogenetic Protein 5; Bone Morphogenetic Protein Receptors; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colforsin; Dose-Response Relationship, Drug; Down-Regulation; GATA6 Transcription Factor; Humans; Hydrocortisone; Insulin-Like Growth Factor I; Phosphorylation; Proto-Oncogene Proteins c-akt; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Steroid 17-alpha-Hydroxylase; Time Factors; Tretinoin; Tumor Cells, Cultured | 2009 |
Inactivation of the Carney complex gene 1 (protein kinase A regulatory subunit 1A) inhibits SMAD3 expression and TGF beta-stimulated apoptosis in adrenocortical cells.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Animals; Apoptosis; Cell Line, Tumor; Colforsin; Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; Cyclic AMP-Dependent Protein Kinases; Gene Silencing; Humans; Male; Mice; RNA, Messenger; RNA, Small Interfering; Smad3 Protein; Transcription, Genetic; Transfection; Transforming Growth Factor beta | 2009 |
Perfluorinated compounds differentially affect steroidogenesis and viability in the human adrenocortical carcinoma (H295R) in vitro cell assay.
Topics: Adrenal Cortex Neoplasms; Alkanesulfonic Acids; Aromatase; Caprylates; Cell Death; Cell Line, Tumor; Cell Survival; Cholesterol Side-Chain Cleavage Enzyme; Colforsin; Dose-Response Relationship, Drug; Flow Cytometry; Fluorocarbons; Humans; Propidium; Radioimmunoassay; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Steroids | 2011 |
Forskolin up-regulates aromatase (CYP19) activity and gene transcripts in the human adrenocortical carcinoma cell line H295R.
Topics: Adenylyl Cyclases; Adrenal Cortex Neoplasms; Aromatase; Carcinoma; Cell Line, Tumor; Colforsin; Cyclic AMP; Dexamethasone; Enzyme Activation; Gene Expression; Genes, Reporter; Humans; Luciferases; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Stimulation, Chemical; Transfection | 2004 |
Expression of the novel adrenocorticotropin-responsive gene selective Alzheimer's disease indicator-1 in the normal adrenal cortex and in adrenocortical adenomas and carcinomas.
Topics: Adolescent; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adrenocorticotropic Hormone; Adult; Aged; Cell Line, Tumor; Colforsin; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Nerve Tissue Proteins; Oxidoreductases Acting on CH-CH Group Donors; Receptors, Corticotropin; RNA, Messenger | 2004 |
Expression of adenylyl cyclase-4 (AC-4) in Y1 and forskolin-resistant adrenal cells.
Topics: Adenylyl Cyclases; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Animals; Colforsin; Cyclic AMP; Drug Resistance; GTP-Binding Protein alpha Subunits, Gs; Mice; Mutation; Promoter Regions, Genetic; Receptors, Corticotropin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2004 |
Forskolin-resistant Y1 adrenal cell mutants are deficient in adenylyl cyclase type 4.
Topics: Adenylyl Cyclases; Adrenal Cortex Neoplasms; Animals; Cell Division; Cell Line, Tumor; Cell Size; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Resistance; Mice; Mutation; Protein Isoforms; RNA, Messenger | 2004 |
Antiestrogens upregulate estrogen receptor beta expression and inhibit adrenocortical H295R cell proliferation.
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Androgens; Apoptosis; Aromatase; Aromatase Inhibitors; Autocrine Communication; Caspases; Cell Line, Tumor; Cell Proliferation; Colforsin; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogen Receptor Modulators; Fas Ligand Protein; fas Receptor; Humans; Letrozole; Membrane Glycoproteins; Nitriles; Promoter Regions, Genetic; RNA, Messenger; Triazoles; Tumor Necrosis Factors | 2005 |
Steroidogenic factor 1 gene transcription is inhibited by transforming growth factor beta.
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Animals; Blotting, Northern; Cell Line, Tumor; Colforsin; Cycloheximide; Dactinomycin; Homeodomain Proteins; Mice; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Steroidogenic Factor 1; Time Factors; Transcription Factors; Transcription, Genetic; Transforming Growth Factor beta | 2005 |
Isolation of forskolin-resistant adrenal cells defective in the adenylate cyclase system.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Adrenal Cortex Neoplasms; Animals; Cell Line; Cell Survival; Clone Cells; Colforsin; Diterpenes; Drug Resistance; Glioma; Kinetics; L Cells; Mice; Rats | 1984 |
Induction of FOS and JUN proteins by adrenocorticotropin and phorbol ester but not by 3',5'-cyclic adenosine monophosphate derivatives.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Alkaloids; Animals; Bucladesine; Colforsin; Cycloheximide; Dactinomycin; Enzyme Induction; Genes, fos; Genes, jun; Kinetics; Mice; Neoplasm Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; RNA, Messenger; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
ACTH induces up-regulation of ACTH receptor mRNA in mouse and human adrenocortical cell lines.
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Angiotensin II; Animals; Base Sequence; Bucladesine; Cell Line; Colforsin; Humans; Mice; Molecular Sequence Data; Receptors, Corticotropin; RNA, Messenger; Tumor Cells, Cultured; Up-Regulation | 1994 |
Regulation of type 1 angiotensin II receptor messenger ribonucleic acid expression in human adrenocortical carcinoma H295 cells.
Topics: Adrenal Cortex Neoplasms; Angiotensin II; Base Sequence; Bucladesine; Calcimycin; Colforsin; Cyclic AMP; Cycloheximide; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Molecular Sequence Data; Phosphoric Diester Hydrolases; Receptors, Angiotensin; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Angiotensin increases aldosterone synthase mRNA levels in human NCI-H295 cells.
Topics: Adrenal Cortex Neoplasms; Aldosterone; Angiotensin II; Colforsin; Cytochrome P-450 CYP11B2; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Humans; RNA, Messenger; Steroid Hydroxylases; Tumor Cells, Cultured | 1993 |
Regulation of human adrenal carcinoma cell (NCI-H295) production of C19 steroids.
Topics: Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Androstenedione; Bucladesine; Colforsin; Cyclic AMP; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Gene Expression Regulation, Neoplastic; Humans; Hydrocortisone; RNA, Messenger; Steroid 17-alpha-Hydroxylase; Tumor Cells, Cultured | 1993 |
Adrenal androgen biosynthesis with special attention to P450c17.
Topics: 3-Hydroxysteroid Dehydrogenases; Adrenal Cortex Neoplasms; Aldehyde-Lyases; Aldosterone; Base Sequence; Calcium; Carcinoma; Cholesterol Side-Chain Cleavage Enzyme; Colforsin; Cyclic AMP; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; DNA Primers; Gene Expression Regulation, Enzymologic; Humans; Hydrocortisone; Molecular Sequence Data; Steroid 17-alpha-Hydroxylase; Tumor Cells, Cultured | 1995 |
Mutations to forskolin resistance result in loss of adrenocorticotropin receptors and consequent reductions in levels of G protein alpha-subunits.
Topics: Adenylyl Cyclases; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Animals; Clone Cells; Colforsin; Drug Resistance; Enzyme Activation; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Humans; Mice; Mutation; Phenotype; Receptors, Adrenergic, beta; Receptors, Corticotropin; Transcription, Genetic; Transfection | 1996 |
Forskolin treatment directs steroid production towards the androgen pathway in the NCI-H295R adrenocortical tumour cell line.
Topics: Adrenal Cortex Neoplasms; Androgens; Androstenedione; Angiotensin II; Colforsin; Corticosterone; Enzyme Activation; Humans; Hydrocortisone; Tumor Cells, Cultured; Zona Fasciculata; Zona Glomerulosa; Zona Reticularis | 1996 |
Characterization of the hamster CYP11B2 gene regulatory regions.
Topics: Adrenal Cortex Neoplasms; Animals; Blotting, Southern; Chloramphenicol O-Acetyltransferase; Colforsin; Cricetinae; Cyclic AMP; Cytochrome P-450 CYP11B2; Enzyme Inhibitors; Gene Expression Regulation; Genes, Reporter; Genetic Vectors; Mice; Promoter Regions, Genetic; Protein Kinase C; Recombinant Fusion Proteins; Staurosporine; TATA Box; Transfection; Tumor Cells, Cultured | 1996 |
ACTH-induced cortisol secretion is mediated by cAMP and PKC in various adrenocortical adenomas.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Angiotensin II; Colforsin; Cushing Syndrome; Cyclic AMP; Cytosol; Female; Humans; Hydrocortisone; Immunoblotting; Male; Membrane Proteins; Middle Aged; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1997 |
Direct stimulation of cortisol secretion from the human NCI H295 adrenocortical cell line by vasoactive intestinal polypeptide.
Topics: Adrenal Cortex Neoplasms; Adrenergic beta-Antagonists; Adrenocortical Carcinoma; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Hydrocortisone; Propranolol; Radioimmunoassay; Stimulation, Chemical; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1997 |
Effect of leptin on ACTH-stimulated secretion of cortisol in rhesus macaques and on human adrenal carcinoma cells.
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Animals; Area Under Curve; Colforsin; Corticotropin-Releasing Hormone; Cosyntropin; Dexamethasone; Humans; Hydrocortisone; Leptin; Macaca mulatta; Male; Mice; Mice, Obese; Radioimmunoassay; Tumor Cells, Cultured | 1999 |
Inhibition of protein tyrosine phosphatase activity blocks shape change & steroidogenesis in Y1 cells.
Topics: Adrenal Cortex Neoplasms; Animals; Cell Size; Colforsin; Dipeptides; Enzyme Inhibitors; Protein Tyrosine Phosphatases; Steroids; Tumor Cells, Cultured | 2000 |
Effects of 3-MeSO2-DDE and some CYP inhibitors on glucocorticoid steroidogenesis in the H295R human adrenocortical carcinoma cell line.
Topics: Adrenal Cortex Neoplasms; Aminoglutethimide; Carcinoma; Chromatography, High Pressure Liquid; Colforsin; Cytochrome P-450 Enzyme Inhibitors; Dichlorodiphenyl Dichloroethylene; Dose-Response Relationship, Drug; Drug Combinations; Environmental Pollutants; Enzyme Inhibitors; Hydrocortisone; Ketoconazole; Metyrapone; Tumor Cells, Cultured | 2002 |
Defective guanyl nucleotide-binding protein beta gamma subunits in a forskolin-resistant mutant of the Y1 adrenocortical cell line.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adrenal Cortex Neoplasms; Animals; Brain; Cattle; Cell Membrane; Chromatography, Gel; Clone Cells; Colforsin; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Macromolecular Substances; Mice; Mutagenesis; Pertussis Toxin; Rats; Rod Cell Outer Segment; Transducin; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1992 |
Forskolin-resistant Y1 mutants harbor defects associated with the guanyl nucleotide-binding regulatory protein, Gs.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Animals; Colforsin; Drug Resistance; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Kinetics; Magnesium; Manganese; Mice; Mutation; NAD; Phenotype; Sodium Fluoride | 1987 |
Dehydroepiandrosterone sulfate (DHEA-S) and 3', 5'-cyclic adenosine monophosphate (cAMP) production in a cultured human adrenocortical carcinoma cell line (SW-13).
Topics: Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; alpha-MSH; Angiotensin II; Calcimycin; Carcinoma, Small Cell; Cell Line; Cholera Toxin; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Epinephrine; Humans; Norepinephrine; Tumor Cells, Cultured | 1988 |
Regulation of tetrahydrobiopterin biosynthesis in cultured adrenal cortical tumor cells by adrenocorticotropin and adenosine 3',5'-cyclic monophosphate.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Animals; Biopterins; Bucladesine; Cell Line; Colforsin; Cosyntropin; Cyclic AMP; GTP Cyclohydrolase; Hydroxyprogesterones; Mice; Mutation; Progesterone; Pteridines | 1986 |
The roles of cAMP and cAMP-dependent protein kinase in forskolin's actions on Y1 adrenocortical tumor cells.
Topics: Adenylyl Cyclases; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Animals; Cell Division; Clone Cells; Colforsin; Cyclic AMP; Mice; Mutation; Protein Kinases; Steroids | 1985 |
Evidence for decreased activity of guanine nucleotide binding protein in adenylate cyclase of cell membranes in human ACTH-unresponsive adrenocortical carcinoma.
Topics: Adenylyl Cyclases; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Carcinoma; Cell Membrane; Cholera Toxin; Colforsin; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Receptors, Corticotropin; Receptors, Pituitary Hormone | 1986 |