colforsin has been researched along with Acute Confusional Senile Dementia in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.70) | 18.7374 |
| 1990's | 12 (44.44) | 18.2507 |
| 2000's | 7 (25.93) | 29.6817 |
| 2010's | 4 (14.81) | 24.3611 |
| 2020's | 3 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, YF; Chi, TY; Ji, XF; Liu, P; Qi, L; Wang, XJ; Zou, LB | 1 |
| Chi, T; Ji, X; Li, Y; Liu, P; Shan, J; Sun, W; Xu, P; Zou, L | 1 |
| Ahmad, F; Jing, Y; Liu, P; Lladó, A | 1 |
| Kumar, A; Singh, N | 2 |
| Alarcón, M; Burgos, CF; Fuentes, E; Hernández, B; Palomo, I; Sepúlveda, C | 1 |
| Abagyan, A; Funkelstein, L; Hook, V; Mosier, C; Toneff, T; Ziegler, M | 1 |
| Deng, HM; Fang, ZY; Gong, CX; Grundke-Iqbal, I; Iqbal, K; Li, HL; Liu, SJ; Wang, JZ; Wang, Q; Zhang, JY | 1 |
| Li, HL; Liu, SJ; Wang, DL; Wang, JZ; Zhang, Y | 1 |
| Baamonde, C; Cairns, N; Dierssen, M; Flórez, J; Lubec, G; Lumbreras, M; Martínez-Cué, C; Sallés, J | 1 |
| Bisel, BE; Henkins, KM; Parfitt, KD | 1 |
| Albasanz, JL; Barrachina, M; Ferrer, I; Martín, M; Perez, S | 1 |
| Liu, XA; Shi, HR; Wang, JZ; Wang, Q; Wang, SH; Zhang, Q; Zhu, LQ | 1 |
| Barger, SW; Fiscus, RR; Hofmann, F; Mattson, MP; Ruth, P | 1 |
| Bohl, J; Lemmer, B; Ohm, T; Schnecko, A; Witte, K | 1 |
| Gibson, GE; Huang, HM | 1 |
| Gandy, S; Greengard, P; Sweeney, D; Xu, H | 1 |
| Bonkale, WL; Cowburn, RF; Fastbom, J; Ravid, R; Wiehager, B; Winblad, B | 1 |
| Algotsson, A; Cowburn, RF; Garlind, A; Johnston, JA; Winblad, B | 1 |
| Adem, A; Cowburn, RF; Gibson, GE; Lannfelt, L; Racchi, M; Vestling, M | 1 |
| Berger, JG; Brown, J; Clader, J; Duffy, RA; Guzik, H; Kozlowski, J; Lachowicz, JE; Lowe, D; McQuade, R; Murgolo, N; Ruperto, V; Strader, CD; Taylor, LA; Tice, M | 1 |
| Bogdanovic, N; Cowburn, RF; Fastbom, J; García-Jiménez, A; Ohm, TG; Winblad, B | 1 |
| Fischmeister, R; Gardier, AM; Lezoualc'h, F; Robert, SJ; Zugaza, JL | 1 |
| Alafuzoff, I; Cowburn, RF; Fowler, CJ; O'Neill, C; Ravid, R; Winblad, B | 1 |
| Bohl, J; Lemmer, B; Ohm, TG | 2 |
| Brooks, DN; Dewar, D; Graham, DI; Horsburgh, K; McCulloch, J | 1 |
27 other study(ies) available for colforsin and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
PINK1 overexpression prevents forskolin-induced tau hyperphosphorylation and oxidative stress in a rat model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Antioxidants; Colforsin; Oxidative Stress; Phosphatidylinositol 3-Kinases; Protein Kinases; Rats; tau Proteins; Ubiquitin-Protein Ligases | 2022 |
Interaction between hyperphosphorylated tau and pyroptosis in forskolin and streptozotocin induced AD models.
Topics: Alzheimer Disease; Amino Acid Chloromethyl Ketones; Animals; Caspase 1; Colforsin; Inflammasomes; Interleukin-18; Interleukin-1beta; Male; PC12 Cells; Phosphorylation; Pyroptosis; Rats; Rats, Sprague-Dawley; Streptozocin; tau Proteins | 2020 |
Chemical Stimulation of Rodent and Human Cortical Synaptosomes: Implications in Neurodegeneration.
Topics: Actins; Aged; Alzheimer Disease; Animals; Brain; Colforsin; Female; Frontal Lobe; Humans; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Middle Aged; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Rolipram; Stimulation, Chemical; Synapses; Synaptosomes | 2021 |
Calcineurin Inhibition and Protein Kinase A Activation Limits Cognitive Dysfunction and Histopathological Damage in a Model of Dementia of the Alzheimer's Type.
Topics: Acetylcholinesterase; Aging; Alzheimer Disease; Animals; Brain; Calcineurin; Calcineurin Inhibitors; Cholinesterase Inhibitors; Cognition Disorders; Colforsin; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Donepezil; Drug Therapy, Combination; Female; Glutathione; Male; Maze Learning; Mice; Peroxidase; Streptozocin; Tacrolimus; Thiobarbituric Acid Reactive Substances; Vasodilator Agents | 2018 |
The cAMP/PKA Pathway Inhibits Beta-amyloid Peptide Release from Human Platelets.
Topics: Adult; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Blood Platelets; Calpain; Cardiovascular Agents; Cells, Cultured; Colforsin; Computer Simulation; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Humans; Models, Molecular; P-Selectin; Platelet Aggregation; Signal Transduction; Young Adult | 2019 |
Beta-amyloid peptides undergo regulated co-secretion with neuropeptide and catecholamine neurotransmitters.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Catecholamines; Cattle; Cells, Cultured; Chromaffin Cells; Colforsin; Cyclic AMP; Dopamine; Enkephalins; Epinephrine; Galanin; Ganglionic Stimulants; Humans; Neuroblastoma; Neurons; Neuropeptide Y; Neuropeptides; Neurotransmitter Agents; Nicotine; Norepinephrine; Peptide Fragments; Secretory Vesicles | 2013 |
Pharmacological activation of protein kinase A improves memory loss and neuropathological changes in a mouse model of dementia of Alzheimer's type.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Brain; Cholinesterase Inhibitors; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dementia; Disease Models, Animal; Female; Glutathione; Male; Maze Learning; Memory Disorders; Mice; Streptozocin | 2017 |
Tau becomes a more favorable substrate for GSK-3 when it is prephosphorylated by PKA in rat brain.
Topics: Alzheimer Disease; Animals; Brain; CDC2 Protein Kinase; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Enzyme Activators; Glycogen Synthase Kinase 3; Hippocampus; Mitogen-Activated Protein Kinases; Phosphorylation; Rats; tau Proteins | 2004 |
A transitory activation of protein kinase-A induces a sustained tau hyperphosphorylation at multiple sites in N2a cells-imply a new mechanism in Alzheimer pathology.
Topics: Alzheimer Disease; Animals; Blotting, Western; Cell Line, Tumor; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Glycogen Synthase Kinase 3; Humans; Mice; Phosphorylation; tau Proteins; Time Factors | 2006 |
Brain G protein-dependent signaling pathways in Down syndrome and Alzheimer's disease.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclases; Aged; Alzheimer Disease; Cerebellum; Cerebral Cortex; Colforsin; Cyclic AMP; Down Syndrome; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Male; Middle Aged; Norepinephrine; Signal Transduction; Type C Phospholipases | 2006 |
Alzheimer amyloid beta-peptide A-beta25-35 blocks adenylate cyclase-mediated forms of hippocampal long-term potentiation.
Topics: Adenylyl Cyclase Inhibitors; Adrenergic beta-Agonists; Alzheimer Disease; Amyloid beta-Peptides; Animals; Colforsin; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Hippocampus; Isoproterenol; Long-Term Potentiation; Magnesium; Male; Peptide Fragments; Rats; Rats, Inbred F344; Synapses; Synaptic Transmission | 2007 |
Up-regulation of adenosine receptors in the frontal cortex in Alzheimer's disease.
Topics: Adenylyl Cyclases; Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Cell Membrane; Colforsin; Cyclic AMP; Female; Frontal Lobe; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Male; Middle Aged; Protein Binding; Receptors, Purinergic P1; Triazines; Triazoles; Tritium; Up-Regulation; Xanthines | 2008 |
Estradiol attenuates tau hyperphosphorylation induced by upregulation of protein kinase-A.
Topics: Alzheimer Disease; Animals; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Estradiol; Female; Humans; Male; Phosphorylation; Recombinant Fusion Proteins; tau Proteins; Up-Regulation | 2008 |
Role of cyclic GMP in the regulation of neuronal calcium and survival by secreted forms of beta-amyloid precursor.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Glutamic Acid; Hippocampus; Neurons; Rats | 1995 |
Adenylyl cyclase activity in Alzheimer's disease brain: stimulatory and inhibitory signal transduction pathways are differently affected.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Aged; Aged, 80 and over; Alzheimer Disease; Brain; Cerebellum; Colforsin; Enzyme Activation; Female; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hippocampus; Humans; Male; Manganese; Middle Aged; Neurotransmitter Agents; Purinergic P1 Receptor Antagonists; Signal Transduction | 1994 |
Altered beta-adrenergic receptor-stimulated cAMP formation in cultured skin fibroblasts from Alzheimer donors.
Topics: Adenylate Cyclase Toxin; Adrenergic beta-Agonists; Aged; Alzheimer Disease; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Fibroblasts; GTP-Binding Proteins; Humans; Isoproterenol; Middle Aged; Pertussis Toxin; Receptors, Adrenergic, beta; Signal Transduction; Skin; Virulence Factors, Bordetella | 1993 |
Metabolism of Alzheimer beta-amyloid precursor protein: regulation by protein kinase A in intact cells and in a cell-free system.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Bucladesine; Cell-Free System; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cytosol; Enzyme Inhibitors; Ethers, Cyclic; Gene Expression Regulation; Golgi Apparatus; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kinetics; Okadaic Acid; PC12 Cells; Protein Kinase C; Protein Processing, Post-Translational; Rats | 1996 |
Impaired G-protein-stimulated adenylyl cyclase activity in Alzheimer's disease brain is not accompanied by reduced cyclic-AMP-dependent protein kinase A activity.
Topics: Adenylyl Cyclases; Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Brain; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Solubility | 1996 |
Decreased beta-adrenoceptor-stimulated adenylyl cyclase activity in lymphocytes from Alzheimer's disease patients.
Topics: Adenylyl Cyclases; Aged; Alzheimer Disease; Colforsin; Dose-Response Relationship, Drug; Female; Humans; Isoproterenol; Lymphocytes; Male; Middle Aged; Receptors, Adrenergic, beta | 1997 |
Differential regulation of adenylyl cyclase in fibroblasts from sporadic and familial Alzheimer's disease cases with PS1 and APP mutations.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Protein Precursor; Cell Line; Colforsin; Female; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Isoproterenol; Male; Membrane Proteins; Middle Aged; Mutation; Presenilin-1; Signal Transduction; Skin | 1997 |
SCH 57790: a novel M2 receptor selective antagonist.
Topics: Acetylcholine; Adenylyl Cyclases; Alzheimer Disease; Animals; Binding Sites; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Humans; Muscarinic Agonists; Muscarinic Antagonists; Oxotremorine; Piperazines; Quinuclidinyl Benzilate; Receptor, Muscarinic M2; Receptors, Muscarinic; Transfection | 1999 |
Quantitative autoradiography of [3H]forskolin binding sites in post-mortem brain staged for Alzheimer's disease neurofibrillary changes and amyloid deposits.
Topics: Adenylyl Cyclases; Aged; Aging; Alzheimer Disease; Autoradiography; Binding Sites; Brain; Brain Chemistry; Colforsin; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; Neurofibrillary Tangles; Plaque, Amyloid; Postmortem Changes | 1999 |
The human serotonin 5-HT4 receptor regulates secretion of non-amyloidogenic precursor protein.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Benzamides; Benzofurans; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; CHO Cells; Colforsin; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Humans; Indoles; Ligands; Memory; Polymerase Chain Reaction; Protein Binding; Protein Isoforms; Radioimmunoassay; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin; Sulfonamides; Time Factors; Transfection; Tumor Cells, Cultured | 2001 |
Adenylyl cyclase activity in postmortem human brain: evidence of altered G protein mediation in Alzheimer's disease.
Topics: Adenylyl Cyclases; Aged; Aged, 80 and over; Aging; Aluminum; Aluminum Compounds; Alzheimer Disease; Brain; Cadaver; Colforsin; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Reference Values; Time Factors | 1992 |
Reduced basal and stimulated (isoprenaline, Gpp(NH)p, forskolin) adenylate cyclase activity in Alzheimer's disease correlated with histopathological changes.
Topics: Adenylyl Cyclases; Aged; Aged, 80 and over; Alzheimer Disease; Brain; Colforsin; Female; Guanylyl Imidodiphosphate; Humans; Isoproterenol; Kinetics; Male; Postmortem Changes; Reference Values | 1991 |
Selective alterations of high affinity [3H]forskolin binding sites in Alzheimer's disease: a quantitative autoradiographic study.
Topics: Adenylyl Cyclases; Aged; Aged, 80 and over; Alzheimer Disease; Animals; Cats; Choline O-Acetyltransferase; Colforsin; Female; GTP-Binding Proteins; Humans; Male | 1990 |
Reduced cAMP-signal transduction in postmortem hippocampus of demented old people.
Topics: Adenylyl Cyclases; Aged; Alzheimer Disease; Colforsin; Cyclic AMP; Enzyme Activation; Female; Guanylyl Imidodiphosphate; Hippocampus; Humans; Isoproterenol; Male; Middle Aged; Signal Transduction | 1989 |