colchicine has been researched along with Colonic Neoplasms in 47 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (6.38) | 18.7374 |
1990's | 15 (31.91) | 18.2507 |
2000's | 16 (34.04) | 29.6817 |
2010's | 11 (23.40) | 24.3611 |
2020's | 2 (4.26) | 2.80 |
Authors | Studies |
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Hamel, E; Kuo, SC; Lednicer, D; Lee, KH; Li, L; Lin, CM; Wang, HK; Wu, TS | 1 |
Chen, L; He, L; Liu, Y; Ma, L; Nie, C; Pu, Y; Shao, M; Wang, F; Wu, W; Wu, Y; Yang, Z; Yu, K | 1 |
Chen, S; Cheng, J; Dong, G; Fang, K; Huang, Y; Li, Y; Sheng, C; Wang, L; Wu, S | 1 |
Jemaà, M; Kifagi, C; Massoumi, R; Serrano, SS | 1 |
Bakar-Ates, F; Kaya-Sezginer, E; Ozmen, N | 1 |
Chen, X; Fang, S; Guo, J; Jiang, J; Zhang, Q; Zheng, C; Zhou, R; Zhou, Y; Zhu, J | 1 |
Backman, V; Kunte, D; Mutyal, NN; Radosevich, A; Roy, HK; Stypula, Y; Tiwari, AK; Wali, R | 1 |
Cassimeris, L; Kumar, R; Louis, XL; Rajasekharan, KN; Sengupta, S; Sivakumar, KC; Sreedevi, KJ; Thamkachy, R; Thomas, NE; Thomas, SA | 1 |
Chen, Y; Ding, J; Huan, XJ; Miao, ZH; Song, SS; Sun, YM; Tian, QT; Wang, W; Wang, YQ; Yang, CH; Yi, JM; Zhang, XF | 1 |
Bharate, SB; Bharate, SS; Bhushan, S; Gupta, BD; Guru, SK; Hamid, A; Hussain, A; Joshi, P; Kumar, A; Kumar, S; Mahajan, G; Mondhe, DM; Qazi, AK; Saxena, AK; Sharma, PR; Singh, B; Vishwakarma, RA; Wani, ZA | 1 |
Huang, Z; Peng, W; Xu, Y | 1 |
Bai, R; Betancourt, T; Dasari, R; Frail, SK; Frolova, LV; Hamel, E; Hill, RM; Kornienko, A; LaBarbera, DV; Medellin, DC; Ontiveros, SJ; Pelly, SC; Rogelj, S; Scott, R; Shuster, CB; van Otterlo, WA; Zhou, Q | 1 |
Bharate, SB; Kumar, A; Mondhe, DM; Saxena, AK; Sharma, PR; Singh, B | 1 |
Gupta, Y; Jain, SK; Kohli, DV | 1 |
Basson, MD; Craig, DH | 1 |
Allen, JD; Kota, BP; Roufogalis, BD | 1 |
Hampong, M; Paddon, H; Pelech, S; Shi, X; Wahyuningsih, D; Zhang, H; Zhang, QJ | 1 |
Brouillard, R; Chabert, P; Coelho, D; Fougerousse, A; Gossé, F; Launay, JF; Raul, F; Schneider, Y; Stutzmann, J | 1 |
GRIEM, ML; MALKINSON, FD | 1 |
Hinrichs, JW; Klappe, K; Kok, JW; Kroesen, BJ; Sietsma, H | 1 |
C -Gaudreault, R; Côté, MF; Deschesnes, RG; Janvier, R; Lacroix, J; Legault, J; Madelmont, JC; Marquis, C; Miot-Noirault, E; Mounetou, E; Petitclerc, E | 1 |
Gossé, F; Raul, F; Schleiffer, R; Schneider, Y; Seiler, N | 1 |
Basson, MD; Thamilselvan, V | 1 |
Forstner, GG; Forstner, JF; McCool, DJ | 1 |
Ausiello, DA; Breuer, W; Cabantchik, IZ; Slotki, IN | 1 |
De Bruijn, EA; Durante, NM; Eggermont, AM; Gheuens, EE; Marquet, RL; Van de Vrie, W; Van Oosterom, AT | 1 |
Brandsch, M; Ganapathy, V; Leibach, FH; Miyamoto, Y | 1 |
Baguley, BC; Kestell, P; Zhuang, L | 1 |
Banan, A; Kokoska, ER; Miller, TA; Rieckenberg, CL; Smith, GS | 1 |
Germain, GS; Horton, JK; Houghton, PJ; Jayashree, BS; Thimmaiah, KN | 1 |
Barra, Y; Mirrione, A; Rimet, O | 1 |
Boquet, P; d'Andrea, L; Far, DF; Guzman, E; Hofman, P; Le Negrate, G; Lemichez, E; Rossi, B; Selva, E | 1 |
Haier, J; Nasralla, M; Nicolson, GL | 1 |
Bombardelli, E; Capelli, G; Danieli, B; De Vincenzo, R; Distefano, M; Ferlini, C; Gaggini, C; Mancuso, S; Morazzoni, P; Riva, A; Scambia, G | 1 |
Filipeanu, CM; Klappe, K; Kok, JW; Koning, H; Müller, M; Veldman, RJ | 1 |
Gil, L; Martínez Morillo, M; Ruiz Gómez, MJ; Souviron, A | 2 |
Cherian, SP; Collins, N; Han, EK; Ng, SC; Tahir, SK | 1 |
Gil, L; Martínez-Morillo, M; Ruiz-Gómez, MJ; Souviron, A | 1 |
Bibby, MC; Nicholson, KM; Phillips, RM; Shnyder, SD | 1 |
Abraham, SC; Iacobuzio-Donahue, C; Montgomery, EA; Torbenson, M; Wu, TT; Yardley, JH | 1 |
Jiang, MC; Liao, CF; Tai, CC | 1 |
Brown, WR; Nagura, H; Nakane, PK | 1 |
Baguley, BC; Holdaway, KM; Thomsen, LL; Zhuang, L; Zwi, LJ | 1 |
Chakraborti, AK; Cushman, M; Gopal, D; Hamel, E; Lin, CM; Nagarathnam, D | 1 |
Chao, CC; Cheng, PW; Lin-Chao, S; Ma, CM | 1 |
Gjøen, T; Kolset, SO; Seljelid, R | 1 |
1 review(s) available for colchicine and Colonic Neoplasms
Article | Year |
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Vitamin B12-mediated transport: a potential tool for tumor targeting of antineoplastic drugs and imaging agents.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Boron Neutron Capture Therapy; Cell Membrane; Chemistry, Pharmaceutical; Colchicine; Colonic Neoplasms; Contrast Media; Drug Carriers; Drug Compounding; Endocytosis; Humans; Lymph Nodes; Molecular Structure; Oligonucleotides, Antisense; Transcobalamins; Vitamin B 12 | 2008 |
46 other study(ies) available for colchicine and Colonic Neoplasms
Article | Year |
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Antitumor agents. 150. 2',3',4',5',5,6,7-substituted 2-phenyl-4-quinolones and related compounds: their synthesis, cytotoxicity, and inhibition of tubulin polymerization.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Small Cell; Cattle; Cell Division; Central Nervous System Neoplasms; Colonic Neoplasms; Female; Humans; Leukemia; Lung Neoplasms; Molecular Structure; Polymers; Quinolones; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Tumor Cells, Cultured | 1994 |
Synthesis and biological evaluation of diarylthiazole derivatives as antimitotic and antivascular agents with potent antitumor activity.
Topics: Angiogenesis Inhibitors; Animals; Antimitotic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Cell Line, Tumor; Cell Movement; Colchicine; Colonic Neoplasms; Drug Resistance, Neoplasm; Female; G2 Phase Cell Cycle Checkpoints; Gene Expression; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Inbred BALB C; Protein Binding; Stilbenes; Structure-Activity Relationship; Thiazoles; Tubulin Modulators; Xenograft Model Antitumor Assays | 2015 |
Scaffold Hopping of Natural Product Evodiamine: Discovery of a Novel Antitumor Scaffold with Excellent Potency against Colon Cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Colonic Neoplasms; Drug Design; G2 Phase; HCT116 Cells; Humans; Mice; Quinazolines; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tubulin Modulators; Xenograft Model Antitumor Assays | 2020 |
Preferential Killing of Tetraploid Colon Cancer Cells by Targeting the Mitotic Kinase PLK1.
Topics: Antimitotic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Colchicine; Colonic Neoplasms; Drug Synergism; Humans; Microtubules; Mitochondria; Mitosis; Paclitaxel; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pteridines; RNA, Small Interfering; Tetraploidy; Tubulin Modulators; Vincristine | 2020 |
The Cellular Uptake and Apoptotic Efficiency of Colchicine is Correlated with Downregulation of MMP-9 mRNA Expression in SW480 Colon Cancer Cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Proliferation; Cell Survival; Colchicine; Colonic Neoplasms; Dose-Response Relationship, Drug; Down-Regulation; Drug Screening Assays, Antitumor; Gene Expression Profiling; Humans; Matrix Metalloproteinase 9; Microscopy, Fluorescence; Real-Time Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship; Tumor Cells, Cultured | 2018 |
Synthesis and biological evaluation of 7-methoxy-1-(3,4,5-trimethoxyphenyl)-4,5-dihydro-2H-benzo[e]indazoles as new colchicine site inhibitors.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colchicine; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Docking Simulation; Molecular Structure; Polymerization; Structure-Activity Relationship | 2019 |
Biological mechanisms underlying structural changes induced by colorectal field carcinogenesis measured with low-coherence enhanced backscattering (LEBS) spectroscopy.
Topics: Adenoma; Animals; Azoxymethane; Cluster Analysis; Colchicine; Colonic Neoplasms; Cytoskeleton; Intestinal Mucosa; Light; Rats; Rats, Inbred F344; Rectum; Scattering, Radiation; Spectrophotometry; Transcriptome; Tubulin Modulators | 2013 |
Reversible action of diaminothiazoles in cancer cells is implicated by the induction of a fast conformational change of tubulin and suppression of microtubule dynamics.
Topics: Cell Proliferation; Colchicine; Colonic Neoplasms; HCT116 Cells; Humans; Hydrogen Bonding; Microtubules; Mitosis; Molecular Dynamics Simulation; Protein Conformation; Thiazoles; Tubulin | 2014 |
Dual targeting of microtubule and topoisomerase II by α-carboline derivative YCH337 for tumor proliferation and growth inhibition.
Topics: Animals; Apoptosis; Binding Sites; Binding, Competitive; Carbolines; Cell Line, Tumor; Colchicine; Colonic Neoplasms; DNA Breaks, Double-Stranded; DNA Topoisomerases, Type II; DNA, Neoplasm; DNA, Superhelical; Drug Interactions; Drug Screening Assays, Antitumor; Etoposide; Humans; Inhibitory Concentration 50; Metaphase; Mice; Mice, Nude; Microtubules; Molecular Structure; Neoplasm Proteins; Paclitaxel; Topoisomerase II Inhibitors; Tubulin; Tubulin Modulators; Vincristine | 2015 |
Colchicine derivatives with potent anticancer activity and reduced P-glycoprotein induction liability.
Topics: Acetamides; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Blotting, Western; Carcinoma, Ehrlich Tumor; Cell Proliferation; Colchicine; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Protein Conformation; Tissue Distribution; Tubulin Modulators; Tumor Cells, Cultured | 2015 |
Colchicine induces apoptosis in HT‑29 human colon cancer cells via the AKT and c-Jun N-terminal kinase signaling pathways.
Topics: Apoptosis; Cell Proliferation; Colchicine; Colonic Neoplasms; HT29 Cells; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction | 2015 |
Novel Microtubule-Targeting 7-Deazahypoxanthines Derived from Marine Alkaloid Rigidins with Potent in Vitro and in Vivo Anticancer Activities.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colchicine; Colonic Neoplasms; Drug Design; Drug Screening Assays, Antitumor; Female; Humans; Marine Toxins; Mice; Mice, Nude; Models, Molecular; Molecular Docking Simulation; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Xanthines | 2016 |
A novel microtubule depolymerizing colchicine analogue triggers apoptosis and autophagy in HCT-116 colon cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Cell Cycle; Cell Proliferation; Colchicine; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HCT116 Cells; Humans; Microtubules; Molecular Structure; Polymerization; Structure-Activity Relationship | 2016 |
Biological impact of mechanical stimuli on tumor metastasis.
Topics: Animals; Cell Proliferation; Colchicine; Colonic Neoplasms; Disease Models, Animal; Mechanotransduction, Cellular; Mice; Neoplasm Metastasis; Stress, Mechanical | 2009 |
The effect of vitamin D3 and ketoconazole combination on VDR-mediated P-gp expression and function in human colon adenocarcinoma cells: implications in drug disposition and resistance.
Topics: Adenocarcinoma; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcitriol; Cell Line, Tumor; Colchicine; Colonic Neoplasms; Drug Resistance, Neoplasm; Humans; Ketoconazole; Receptors, Calcitriol; Rhodamine 123 | 2011 |
Nocodazole-induced p53-dependent c-Jun N-terminal kinase activation reduces apoptosis in human colon carcinoma HCT116 cells.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Arsenates; Blotting, Western; Colchicine; Colonic Neoplasms; Cytosol; DNA Fragmentation; Enzyme Activation; Flow Cytometry; Genes, p53; Gout Suppressants; Humans; JNK Mitogen-Activated Protein Kinases; Kinetics; Mitogen-Activated Protein Kinases; Nocodazole; Oligonucleotides; Phosphorylation; Plasmids; Protein Structure, Tertiary; Signal Transduction; Time Factors; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Vinblastine | 2002 |
Resveratrol analog (Z)-3,5,4'-trimethoxystilbene is a potent anti-mitotic drug inhibiting tubulin polymerization.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Apoptosis; Binding Sites; Caco-2 Cells; Cell Cycle; Cell Division; Colchicine; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Gout Suppressants; Humans; Microtubules; Mitosis; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Polymers; Resveratrol; Stilbenes; Tubulin; Tubulin Modulators; Vinblastine | 2003 |
MODIFICATION OF RADIATION RESPONSE OF TISSUE BY COLCHICINE PRELIMINARY CLINICAL EVALUATION.
Topics: Adenocarcinoma; Brachial Plexus; Carcinoma; Carcinoma, Squamous Cell; Colchicine; Colonic Neoplasms; Esophageal Neoplasms; Fibrosarcoma; Gallbladder Neoplasms; Humans; Lung Neoplasms; Male; Mycosis Fungoides; Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms; Skin Neoplasms; Stomach Neoplasms; Thyroid Neoplasms; Tongue Neoplasms; Toxicology; Urinary Bladder Neoplasms | 1964 |
MRP1 and glucosylceramide are coordinately over expressed and enriched in rafts during multidrug resistance acquisition in colon cancer cells.
Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Colchicine; Colonic Neoplasms; Drug Resistance, Neoplasm; Glucosylceramides; Glucosyltransferases; HT29 Cells; Humans; Membrane Microdomains; Sphingolipids | 2004 |
Antiangiogenic and antitumoral activity of phenyl-3-(2-chloroethyl)ureas: a class of soft alkylating agents disrupting microtubules that are unaffected by cell adhesion-mediated drug resistance.
Topics: Actins; Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Cell Division; Cell Line, Tumor; Cells, Cultured; Chick Embryo; Colchicine; Colonic Neoplasms; Cricetinae; Cytoskeleton; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Endothelium, Vascular; Extracellular Matrix; Humans; Mice; Mice, Inbred BALB C; Microtubules; Paclitaxel; Tubulin; Urea | 2004 |
Polyploidisation of metastatic colon carcinoma cells by microtubule and tubulin interacting drugs: effect on proteolytic activity and invasiveness.
Topics: Cell Division; Cell Line, Tumor; Colchicine; Colonic Neoplasms; Humans; Matrix Metalloproteinase 7; Microtubules; Neoplasm Invasiveness; Paclitaxel; Polyploidy; Tissue Plasminogen Activator; Tubulin | 2004 |
The role of the cytoskeleton in differentially regulating pressure-mediated effects on malignant colonocyte focal adhesion signaling and cell adhesion.
Topics: Cell Adhesion; Cell Line, Tumor; Cells, Cultured; Colchicine; Colon; Colonic Neoplasms; Cytochalasin D; Cytoskeleton; Dimethyl Sulfoxide; Humans; Integrins; Models, Biological; Paclitaxel; Phalloidine; Pressure; Signal Transduction | 2005 |
Regulated and unregulated pathways for MUC2 mucin secretion in human colonic LS180 adenocarcinoma cells are distinct.
Topics: Adenocarcinoma; Biomarkers, Tumor; Calcimycin; Carbachol; Cell Size; Colchicine; Colonic Neoplasms; Cytochalasin D; Cytoplasmic Granules; Golgi Apparatus; Humans; Microscopy, Electron; Monensin; Mucin-2; Mucins; Neoplasm Proteins; Nocodazole; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Induction of multidrug resistance downregulates the expression of CFTR in colon epithelial cells.
Topics: Adenocarcinoma; Alkaline Phosphatase; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Cell Line; Colchicine; Colon; Colonic Neoplasms; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Resistance; Epithelium; Gene Expression Regulation, Neoplastic; Humans; Membrane Glycoproteins; Membrane Proteins; Sodium-Potassium-Exchanging ATPase; Tumor Cells, Cultured | 1993 |
In vitro and in vivo chemosensitizing effect of cyclosporin A on an intrinsic multidrug-resistant rat colon tumour.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Colchicine; Colonic Neoplasms; Cyclosporine; Drug Resistance; Drug Synergism; Male; Membrane Glycoproteins; Neoplasm Proteins; Rats; Rats, Inbred Strains; Tumor Cells, Cultured; Verapamil | 1993 |
Regulation of taurine transport in human colon carcinoma cell lines (HT-29 and Caco-2) by protein kinase C.
Topics: Biological Transport; Colchicine; Colonic Neoplasms; Cycloheximide; Cytochalasin D; Dactinomycin; Humans; Kinetics; Protein Kinase C; Taurine; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1993 |
Increased plasma serotonin following treatment with flavone-8-acetic acid, 5,6-dimethylxanthenone-4-acetic acid, vinblastine, and colchicine: relation to vascular effects.
Topics: Animals; Antineoplastic Agents; Colchicine; Colonic Neoplasms; Dose-Response Relationship, Drug; Flavonoids; Hydroxyindoleacetic Acid; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Serotonin; Time Factors; Vinblastine; Xanthenes; Xanthones | 1997 |
Protection against ethanol injury by prostaglandin in a human intestinal cell line: role of microtubules.
Topics: 16,16-Dimethylprostaglandin E2; Anti-Ulcer Agents; Cell Line; Cell Survival; Colchicine; Colon; Colonic Neoplasms; Ethanol; Humans; Microtubules; Paclitaxel; Tumor Cells, Cultured | 1998 |
Characterization of 2-chloro-N10-substituted phenoxazines for reversing multidrug resistance in cancer cells.
Topics: Adenocarcinoma; Adenosine Triphosphatases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chlorine; Clone Cells; Colchicine; Colonic Neoplasms; Drug Resistance, Multiple; Humans; KB Cells; Molecular Structure; Oxazines; Paclitaxel; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured; Vinblastine | 1998 |
Multidrug-resistant phenotype influences the differentiation of a human colon carcinoma cell line.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biomarkers; Carcinoembryonic Antigen; Cell Differentiation; Colchicine; Colonic Neoplasms; Culture Media; Doxorubicin; Drug Resistance, Multiple; Flow Cytometry; Fluorescent Antibody Technique; Galactose; Gene Expression Regulation, Neoplastic; Glucose; Humans; Microscopy, Electron; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transfection; Tumor Cells, Cultured | 1999 |
Neutrophil F-actin and myosin but not microtubules functionally regulate transepithelial migration induced by interleukin 8 across a cultured intestinal epithelial monolayer.
Topics: Actins; ADP Ribose Transferases; Bacterial Toxins; Calcium; Cell Adhesion; Cells, Cultured; Chelating Agents; Chemotaxis, Leukocyte; Colchicine; Colonic Neoplasms; Cytochalasin B; Cytoskeleton; Diacetyl; Egtazic Acid; Epithelial Cells; Humans; Interleukin-8; Intestinal Mucosa; Microtubules; Myosins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Paclitaxel; Phalloidine; Tumor Cells, Cultured | 1999 |
Different adhesion properties of highly and poorly metastatic HT-29 colon carcinoma cells with extracellular matrix components: role of integrin expression and cytoskeletal components.
Topics: Acrylamide; Antibodies; Cell Adhesion; Colchicine; Colonic Neoplasms; Cycloheximide; Cytochalasin D; Cytoskeleton; Extracellular Matrix; Humans; Integrins; Neoplasm Metastasis; Nocodazole; Tumor Cells, Cultured | 1999 |
Biological evaluation on different human cancer cell lines of novel colchicine analogs.
Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Cell Cycle; Colchicine; Colonic Neoplasms; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Leukemia; Tubulin; Tumor Cells, Cultured | 1999 |
Differential expression of sphingolipids in MRP1 overexpressing HT29 cells.
Topics: Antineoplastic Agents; ATP-Binding Cassette Transporters; Cell Survival; Ceramides; Colchicine; Colonic Neoplasms; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Etoposide; Fluoresceins; Galactosylceramides; Glucosylceramides; HT29 Cells; Humans; Immunoblotting; Immunohistochemistry; Microscopy, Confocal; Microtubules; Mitosis; Multidrug Resistance-Associated Proteins; Paclitaxel; Propionates; Quinolines; Signal Transduction; Sphingolipids; Vincristine | 2000 |
Multidrug resistance increment in a human colon carcinoma cell line by colchicine.
Topics: Adenocarcinoma; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Colchicine; Colonic Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Mitomycin; Tumor Cells, Cultured; Verapamil; Vinblastine; Vincristine | 2000 |
Modulation of paclitaxel resistance by annexin IV in human cancer cell lines.
Topics: Annexin A4; Blotting, Western; Colchicine; Colonic Neoplasms; DNA, Complementary; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Electrophoresis, Gel, Two-Dimensional; Gene Expression Regulation, Neoplastic; Growth Inhibitors; Humans; Lung Neoplasms; Neoplasm Proteins; Nocodazole; Paclitaxel; Recombinant Fusion Proteins; Transfection; Tubulin Modulators; Tumor Cells, Cultured | 2000 |
P-glycoprotein, glutathione and glutathione S-transferase increase in a colon carcinoma cell line by colchicine.
Topics: Adenocarcinoma; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Colchicine; Colonic Neoplasms; Drug Resistance, Multiple; Glutathione; Glutathione Transferase; Humans; Mitomycin; Tumor Cells, Cultured; Vinblastine; Vincristine | 2000 |
In vitro and in vivo activity of LS 4477 and LS 4559, novel analogues of the tubulin binder estramustine.
Topics: Animals; Antineoplastic Agents, Alkylating; Binding, Competitive; Colchicine; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Estramustine; Inhibitory Concentration 50; Male; Mice; Microtubules; Prodrugs; Swine; Tubulin; Tubulin Modulators; Tumor Cells, Cultured | 2002 |
Colchicine effect in a colonic hyperplastic polyp. A lesion mimicking serrated adenoma.
Topics: Adenoma; Antigens, Nuclear; Biomarkers, Tumor; Cell Polarity; Colchicine; Colonic Neoplasms; Colonic Polyps; Diagnosis, Differential; Female; Humans; Hyperplasia; Immunohistochemistry; Ki-67 Antigen; Middle Aged; Mitosis; Nuclear Proteins | 2002 |
Verapamil sensitisation to alkaloids on colchicine-selected human colon adenocarcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Cell Survival; Colchicine; Colonic Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Tumor Cells, Cultured; Verapamil; Vinblastine; Vincristine | 2001 |
CAS/CSE 1 stimulates E-cadhrin-dependent cell polarity in HT-29 human colon epithelial cells.
Topics: Acrylamide; Apoptosis; Blotting, Western; Cadherins; Cell Polarity; Cellular Apoptosis Susceptibility Protein; Colchicine; Colonic Neoplasms; Cytochalasin D; Cytoskeleton; DNA; Epithelial Cells; Humans; Oligonucleotides, Antisense; Precipitin Tests; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured | 2002 |
Translocation of dimeric IgA through neoplastic colon cells in vitro.
Topics: Binding Sites, Antibody; Biological Transport; Cell Transformation, Neoplastic; Colchicine; Colonic Neoplasms; Cytochalasin B; Horseradish Peroxidase; Humans; Immunoglobulin A; Secretory Component; Trypsin | 1979 |
Inhibition of growth of colon 38 adenocarcinoma by vinblastine and colchicine: evidence for a vascular mechanism.
Topics: Adenocarcinoma; Animals; Colchicine; Colonic Neoplasms; Drug Resistance; Leukemia, Experimental; Mice; Mice, Inbred Strains; Necrosis; Nitrates; Vinblastine | 1991 |
Synthesis and evaluation of stilbene and dihydrostilbene derivatives as potential anticancer agents that inhibit tubulin polymerization.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Chemical Phenomena; Chemistry; Colchicine; Colonic Neoplasms; Humans; Lung Neoplasms; Melanoma; Molecular Structure; Polymers; Stilbenes; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Tumor Cells, Cultured | 1991 |
Increased mdr gene expression and decreased drug accumulation in a human colonic cancer cell line resistant to hydrophobic drug.
Topics: Antineoplastic Agents; Base Sequence; Biological Transport; Blotting, Northern; Blotting, Southern; Cell Line; Cisplatin; Colchicine; Colonic Neoplasms; DNA, Neoplasm; Doxorubicin; Drug Resistance; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Mitomycin; Mitomycins; Puromycin; RNA, Messenger; Vinblastine | 1990 |
Binding of metastatic colon carcinoma cells to liver macrophages.
Topics: Animals; Carcinoma; Cell Adhesion; Cell Line; Colchicine; Colonic Neoplasms; Cytochalasin B; Cytotoxicity, Immunologic; Egtazic Acid; Kupffer Cells; Liver Neoplasms; Macrophages; Male; Monosaccharides; Peritoneal Cavity; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Trypsin | 1989 |