colchicine has been researched along with Benign Neoplasms in 232 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 120 (51.72) | 18.7374 |
| 1990's | 3 (1.29) | 18.2507 |
| 2000's | 12 (5.17) | 29.6817 |
| 2010's | 63 (27.16) | 24.3611 |
| 2020's | 34 (14.66) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, JY; Chang, YL; Chen, CP; Chen, CT; Chen, LT; Hsieh, HP; Kuo, CC; Lee, SJ; Liou, JP; Pan, WY | 1 |
| Fang, X; Shao, L; Wang, S; Zhang, H | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Anchoori, RK; Bai, R; Diest, PJ; Hallur, G; Hamel, E; Hidalgo, M; Khan, SR; Kortenhorst, MS; Sarkar, T | 1 |
| Chang, CY; Chang, JY; Chiang, YK; Coumar, MS; Hsieh, HP; Kuo, CC; Lai, MJ; Liou, JP; Reddy, GR; Tan, UK; Wu, SY; Yeh, JY | 1 |
| Chang, CM; Chao, YS; Chen, CP; Chen, CT; Chen, TW; Chuu, JJ; Hu, CB; Huang, CL; Huang, CY; Hwang, DR; Li, WT; Lin, CC; Lin, CH; Lin, HL; Shen, CC; Song, JS; Tseng, HY; Wang, HS | 1 |
| Chen, X; Chen, Y; Gao, C; Jiang, Y; Li, Y; Liu, H; Luan, X; Tan, C; Zhang, C | 1 |
| Li, X; Lu, X; Sun, J; Wen, Q; Xing, M; Yang, XH; Zhao, TT; Zhu, HL | 1 |
| Duh, TH; Lin, YT; Liu, YP; Lo, YH; Lu, PJ; Wu, MJ | 1 |
| Cao, D; Chen, J; Chen, L; Han, X; Lei, K; Liang, X; Ma, L; Peng, A; Peng, F; Qiu, J; Ran, Y; Sang, Y; Tang, M; Wang, G; Wen, J; Wu, W; Xiang, M; Yang, Z; Ye, H; Zhang, R | 1 |
| Akula, B; Bharathi, EV; Billa, VK; Cosenza, SC; Gallo, JM; Lv, H; Mallireddigari, MR; Padgaonkar, A; Pallela, VR; Reddy, EP; Reddy, MV; Subbaiah, DR | 1 |
| Cao, D; Chen, J; Chen, L; Han, X; He, L; Liu, J; Ma, L; Peng, A; Peng, F; Sang, Y; Wang, G; Wei, Y; Wu, W; Xiang, M; Yang, Z | 1 |
| Chang, CY; Chang, JY; Chang, YT; Kuo, CC; Lai, MJ; Lee, HY; Liou, JP; Liu, YM; Mehndiratta, S; Nien, CY; Pan, SL; Su, MC; Wu, JS; Wu, SY | 1 |
| Alfonsi, R; Bai, R; Bolognesi, A; Brancale, A; Coluccia, A; Di Marcotullio, L; Dondio, G; Famiglini, V; Gulino, A; Hamel, E; La Regina, G; Lavia, P; Mazzoccoli, C; Mercurio, C; Miele, A; Nalli, M; Novellino, E; Passacantilli, S; Pelliccia, S; Rensen, WM; Ruggieri, V; Silvestri, R; Sisinni, L; Varasi, M; Vultaggio, S | 1 |
| Barasoain, I; Carda, M; Díaz, JF; Díaz-Oltra, S; Falomir, E; Marco, JA; Murga, J; Redondo-Horcajo, M; Vilanova, C | 1 |
| Chen, C; Gao, C; Jiang, Y; Li, B; Li, L; Li, X; Liu, H; Sun, Q; Tan, C; Zhang, B | 1 |
| Capuano, B; DeBono, A; Scammells, PJ | 1 |
| Alfonsi, R; Bai, R; Bigogno, C; Brancale, A; Caraglia, M; Coluccia, A; Da Pozzo, E; Di Marcotullio, L; Dondio, G; Famiglini, V; Gulino, A; Hamel, E; La Regina, G; Lavia, P; Marinelli, L; Martini, C; Mazzoccoli, C; Mercurio, C; Miele, A; Monti, L; Nalli, M; Novellino, E; Passacantilli, S; Pelliccia, S; Porto, S; Ricci, B; Ruggieri, V; Santoni, A; Silvestri, R; Soriani, A; Varasi, M; Verrico, A; Vultaggio, S | 1 |
| An, W; Meng, T; Miao, Z; Shen, J; Wang, W; Yu, T; Zhang, Y | 1 |
| Hadfield, JA; Rossington, SB; Shnyder, SD; Wallace, TW; Williams, KJ | 1 |
| Abouzid, KAM; Al-Ansary, GH; El-Naggar, AM | 1 |
| Han, HW; Lin, HY; Lu, GH; Qi, JL; Sun, WX; Tang, CY; Wang, XM; Yang, YH; Yang, YS | 1 |
| Bueno, O; Camarasa, MJ; Díaz, JF; Estévez-Gallego, J; Liekens, S; Noppen, S; Pérez-Pérez, MJ; Priego, EM; Quesada, E; Tobajas, G | 1 |
| Behera, C; Chanda, D; Fatima, K; Gupta, AK; Hasanain, M; Khwaja, S; Kour, A; Luqman, S; Mondhe, DM; Negi, AS; Sarkar, J; Shanker, K; Singh, A | 1 |
| Chen, K; Fan, J; Ma, X; Qin, YJ; Zhang, YL; Zhu, HL | 1 |
| Attanzio, A; Barraja, P; Carbone, A; Cascioferro, S; Cirrincione, G; Diana, P; Montalbano, A; Parrino, B; Spanò, V; Tesoriere, L; Ullo, S | 1 |
| Bao, JX; Fu, JY; Han, HW; Lin, HY; Lu, GH; Lu, YT; Qi, JL; Sun, WX; Wang, MY; Wang, XM; Wang, YS; Wen, ZL; Yang, MK; Yang, YH | 1 |
| Al-Bajalan, HM; Alali, FQ; Chong, KF; Ghawanmeh, AA; Mackeen, MM | 1 |
| Li, W; Li, X; Lu, L; Shuai, W; Xu, F; Xu, J; Xu, S; Yang, L; Yao, H; Zhu, H; Zhu, Z | 1 |
| Cheng, J; Liang, Y; Tang, H; Wang, Y | 1 |
| Allegro, D; Barbier, P; Combes, S; Fedorov, AY; Gavryushin, AE; Gigant, B; Kobanova, DA; Shchegravina, ES; Shchekotikhin, AE; Svirshchevskaya, EV; Varela, PF | 1 |
| Cai, X; Chen, L; Hong, F; Lei, L; Li, D; Li, N; Ma, X; Ni, H; Shi, M; Tang, M; Wang, L; Yan, W; Yang, J; Ye, H; Zhang, R; Zheng, W; Zheng, Y | 1 |
| Bai, P; Chen, L; Fu, S; Han, K; He, W; Li, J; Li, Y; Liu, J; Liu, Y; Shi, M; Tang, M; Xie, L; Yan, W; Yang, J; Yang, Z; Ye, H; Zhang, C; Zhu, Z | 1 |
| Li, X; Lin, H; OuYang, F; Pang, Y; Yan, J; Zhang, W; Zhou, J | 1 |
| Valipour, M | 1 |
| Flores-Tafoya, PJ; Fragoso-Serrano, M; Leitão, SG; Moreno-Velasco, A; Pereda-Miranda, R | 1 |
| Kumar, D; Kumar, S; Sharma, P; Shri, R | 1 |
| Fu, XJ; Li, YR; Liu, FF; Liu, WB; Song, J; Tian, XY; Xu, Y; Zhang, SY; Zhang, YF | 1 |
| Barnieh, FM; Falconer, RA; Garland, H; Loadman, PM; Ribeiro Morais, G | 1 |
| Agarwal, S; Asati, V; Chourasia, P; Das, R; Kashaw, SK; Kashaw, V | 1 |
| Alhajamee, M; Homayouni Tabrizi, M; Khademi, D; Sadeghzadeh, F; Torshizi, GH; Ziaratnia, AS | 1 |
| Boček, I; Daelemans, D; Hok, L; Hranjec, M; Persoons, L; Vianello, R | 1 |
| Islam, MA; Islam, O; Rahaman, MS; Shanto, PC; Simal-Gandara, J; Siraj, MA | 1 |
| Cerda-García-Rojas, CM; López-López, E; Medina-Franco, JL | 1 |
| Kim, J; Kim, T; Nimse, SB; Song, KS; Warkad, SD | 1 |
| Abel, AC; Alcaro, S; Bai, R; Barraja, P; Barreca, M; Bertoni, F; Bivacqua, R; Cascione, L; Gaudio, E; Hamel, E; Maruca, A; Montalbano, A; Prota, AE; Raimondi, MV; Rinaldi, A; Rocca, R; Spanò, V; Steinmetz, MO; Tarantelli, C | 1 |
| Hawash, M | 1 |
| Bao, C; Bao, Y; Chen, G; Gao, X; Jing, Y; Li, B; Li, X; Song, D; Wang, Y; Waxman, S; Wu, C; Yang, J | 1 |
| Borys, F; Fabczak, H; Joachimiak, E; Krawczyk, H; Poterała, M; Tobiasz, P | 1 |
| Bharathiraja, P; Cardoso, DSP; Ferreira, MU; Lakra, DS; Mulhovo, S; Rajendra Prasad, N | 1 |
| Rathinasamy, K; Sebastian, J | 1 |
| Chein, RJ; Chen, JJW; Cheng, TR; Chou, TH; Chung, WC; Hong, TM; Lee, TC; Lin, MS; Tsai, ML; Weng, CW; Wong, CH; Yang, PC; Yang, SC | 1 |
| Du, L; Risinger, AL | 1 |
| Camara Planek, MI; Okwuosa, TM; Silver, AJ; Volgman, AS | 1 |
| Chambers, TC; Huczyński, A; Klejborowska, G; Maj, E; Moshari, M; Preto, J; Tuszynski, JA; Urbaniak, A; Wietrzyk, J | 1 |
| B, S; Cha-Molstad, H; Han, HJ; Han, J; Hwang, J; Kim, BY; Kim, SO; Kwon, YT; Lee, KH; N R, T; Park, C; Ryoo, IJ; Soung, NK; Woo, M | 1 |
| Chen, X; Du, T; Ji, M; Li, Y; Lin, S; Liu, Y; Lu, D; Sheng, L; Wang, Q; Xu, H; Xue, N; Zhang, J; Zhang, K; Zhang, Y; Zhang, Z | 1 |
| Chang, SA; Cho, J; Kim, EK; Kim, SR; Lee, SC; Park, SJ; Park, SW | 1 |
| Abbate, A; Dell, M; Ho, AC; Mbualungu, J; VAN Tassell, B; Vecchiè, A | 1 |
| Chen, ZS; Li, W; Liu, Y; Shuai, W; Tan, Y; Xu, J; Xu, S; Yang, DH; Yang, L; Yao, H; Zheng, T; Zhu, H; Zhu, Z | 1 |
| Battastini, AMO; Costa, LT; de Fraga Dias, A; de Paula da Silva, CHT; Dos Santos, CBR; Federico, LB; Figueiró, F; Rosa, JMC; Silva, GM | 1 |
| Gupta, R; Joshi, N; Kale, A; Nagotu, S; Parkar, H; Pathak, S | 1 |
| Barasoain, I; de Asís Balaguer, F; Díaz, JF; Lamberth, C; Olieric, N; Sáez-Calvo, G; Sharma, A; Steinmetz, MO | 1 |
| Ashchyan, HJ; Gowda, A; James, WD; McMahon, CM; Micheletti, RG; Nelson, CA; Noe, MH; Perl, AE; Rosenbach, M; Wu, B | 1 |
| Bai, P; Chen, L; Chen, Q; Hu, Y; Li, D; Li, W; Qiu, Q; Wang, T; Wang, Y; Wei, Y; Yan, W; Yang, J; Yang, S; Yang, T; Ye, H; Yu, Y; Zhou, Y | 1 |
| A Osman, EE; Abou-Seri, SM; Eid, NM; El Moghazy, SM; Moussa, SA | 1 |
| Azad, N; Iyer, AKV; Kaushik, V; Way, LF; Yakisich, JS | 1 |
| Bartl, F; Chambers, TC; Delgado, M; Huczyński, A; Maj, E; Majcher, U; Moshari, M; Tuszynski, JA; Urbaniak, A; Wietrzyk, J | 1 |
| Bi, Y; Li, W; Ma, C; Shuai, W; Sun, H; Xu, F; Xu, J; Xu, S; Yao, H; Zhu, Z | 1 |
| Duan, Y; Liu, W; Mao, Y; Song, C; Tian, L | 1 |
| Deodhar, A | 1 |
| Ambudkar, SV; Anreddy, N; Chen, ZS; Chufan, EE; Patel, A; Singh, S; Sodani, K; Stephani, R; Tiwari, AK | 1 |
| Bedi, PM; Dhar, KL; Nepali, K; Ojha, R; Sharma, S | 1 |
| Bai, R; Dohle, W; Ferrandis, E; Fiore, A; Hamel, E; Jourdan, FL; Kasprzyk, PG; Leese, MP; Major, MR; Newman, SP; Potter, BV; Purohit, A | 1 |
| Atkinson, JM; Cooper, P; Falconer, RA; Gill, JH; Loadman, PM; Patterson, LH; Ribeiro Morais, G; Shnyder, SD | 1 |
| Naik, PK; Santoshi, S | 1 |
| Álvarez, R; Medarde, M; Peláez, R | 1 |
| Carta, D; Ferlin, MG | 1 |
| Ethiraj, KR; Sharma, N; Vindya, NG; Yadav, M | 1 |
| Ji, YT; Liu, YN; Liu, ZP | 1 |
| Goto, M; Hamel, E; Lee, KH; Nakagawa-Goto, K; Oda, A; Ohkoshi, E | 1 |
| Chang, SJ; Hsieh, MC; Kuo, MC | 1 |
| Ammar, M; Amouri, M; Boudawara, T; Boudaya, S; Khabir, A; Masmoudi, A; Turki, H | 1 |
| Kumar, A; Mondhe, DM; Sharma, PR | 1 |
| Banerjee, A; Goping, IS; Hassani, B; Huzil, T; Johnson, L; Luduena, R; Mane, JY; Rieger, A; Tuszynski, JA; Winter, P | 1 |
| Ahmadi, S; Habibpour, E | 1 |
| Balderas-Rentería, I; Bandyopadhyay, D; García-Pérez, CA; Henschke, L; Olazarán, FE; Reyes-Figueroa, AD; Rivera, G | 1 |
| LUDFORD, RJ | 1 |
| COSTABILE, L; LO DUCA, N | 1 |
| REVIGLIO, JM | 1 |
| DUMAZER, R; TILLIER, H | 1 |
| BIRABEN, J; DOUTRE, LP | 1 |
| Giles, FJ; Mooberry, SL; Risinger, AL | 1 |
| LEVINE, M; SILVER, GB | 1 |
| Charron, D; Gelin, C; Marin-Esteban, V; Mooney, N | 1 |
| Huzil, T; Izbicka, E; Johnson, L; Luduena, RF; Mane, JY; Tseng, CY; Tuszynski, JA; Winter, P | 1 |
| Guo, DA; Liu, X; Yue, QX | 1 |
| Aggarwal, BB; Chaturvedi, MM; Kannappan, R; Phromnoi, K; Prasad, S; Ravindran, J; Reuter, S; Sung, B; Yadav, VR | 1 |
| Hong, JH; Hur, GM; Jeon, J; Jeong, JE; Kang, SW; Lee, H; Ryu, YS; Shin, S; Zhang, T | 1 |
| Lemasters, JJ; Maldonado, EN; Mullins, MR; Patnaik, J | 1 |
| Jain, N; Kalivendi, SV; Reddy, PS; Shaik, TB; Sreedhar, B; Vasantha, G; Yada, D | 1 |
| Joshi, HC; Naik, PK; Rai, A; Santoshi, S | 1 |
| Brancale, A; Coluccia, A; Sabbadin, D | 1 |
| Balzarini, J; Baraldi, PG; Bermejo, J; Brancale, A; Carrion, MD; Chen, L; Cruz-Lopez, O; Estévez, F; Estévez, S; Hamel, E; Kim, JG; Kimatrai Salvador, M; Lopez-Cara, C; Ricci, A; Romagnoli, R | 1 |
| Kashiwada, Y; Kurimoto, S; Lee, KH; Takaishi, Y | 1 |
| Addlagatta, A; Kamal, A; Kishor, C; Pal-Bhadra, M; Pushpavalli, SN; Ramaiah, MJ; Sharma, P; Srikanth, YV; Sultana, F; Viswanath, A | 1 |
| Ahn, S; Chen, J; Costello, TA; Dalton, JT; Dalton, MN; Li, CM; Li, W; Lu, Y; Miller, DD; Narayanan, R; Snyder, LM | 1 |
| Covell, DG | 1 |
| Sivakumar, G | 1 |
| Ludueña, RF; Xu, K | 1 |
| Gleason, JR; Laviano, A; Meguid, MM; Rossi-Fanelli, F | 1 |
| GALLICO, E | 1 |
| HUANT, E | 4 |
| BACK, A; WALASZEK, EJ | 1 |
| BISHOP, CJ; McGOWAN, LJ | 1 |
| STOGER, R | 1 |
| GARDINI, GF | 1 |
| LETTRE, H; SEIDLER, E; WRBA, H | 1 |
| ABBOZZO, G; ROMUALDI, G; VOLTERRA, M | 1 |
| HUGUENIN, R; SARACINO, R; TRUHAUT, R | 1 |
| AKAISHI, K; AKAMA, Y; SATO, K; YOSHIMATSU, S | 1 |
| ZBINDEN, F | 1 |
| CZIGANY, J; DUCHON, J; TARCSY, G | 2 |
| HOMANN, W; OTTO, H | 1 |
| NEUKOMM, S | 1 |
| PENTTINEN, K; SAXEN, E | 1 |
| CARRATINO, L; TAGLIAFERRO, A | 1 |
| UNGAR, E | 1 |
| AKAISHI, K; HARADA, K; SATO, K | 1 |
| PAOLINO, W; PIERRI, G; RESEGOTTI, L | 1 |
| MOLINATTI, GM; PAOLINO, W; PIERRI, G; RESEGOTTI, L | 1 |
| PAOLINO, W; PIERRI, G; VERCELLINO, E | 1 |
| SARACINO, R; TRUHAUT, R | 1 |
| D'INCERTI BONINI, L | 1 |
| SELIGER, H | 1 |
| KOMAR, VE; VOL'FSON, NI | 1 |
| WRBA, H | 1 |
| JANET, J | 1 |
| TRONCHET, J | 1 |
| TSUDA, F | 1 |
| JONSSON, U; LARSEN, W; LESSNER, H; LOEB, V | 1 |
| KAJIHARA, K | 1 |
| EWANIUK, MH; HRUSHOVETZ, SB | 1 |
| ERIDANI, S; TAGLIORETTI, D; TESTERO, S; TISO, R | 1 |
| GOLDENBERG, DM | 1 |
| VARGAS, M | 1 |
| BLOCK, GE; LANCASTER, JR | 1 |
| CASSINGENA, R; MERUCCI, P; MIGGIANO, V; ZITO, R | 1 |
| DOGLIOTTI, GC | 1 |
| MOLONEY, WC | 1 |
| LEBLOND, CP | 1 |
| CHUDAKOVA, MA; LARIONOV, LF | 1 |
| KELLNER, B; SUGAR, J | 1 |
| HUTCHISON, DJ | 1 |
| BADER, JP | 1 |
| CARDINALI, G; CARDINALLI, G; HANDLER, AH | 1 |
| ARMSTRONG, JG; JANSEN, CJ; JOHNSON, IS; NEUSS, N | 1 |
| KIMURA, Y; YAMAMOTO, K | 1 |
| PHILLIPS, RW | 1 |
| KAWAJI, H; KAZIWARA, K; MATSUMOTO, T; USUI, T; WATANABE, J | 1 |
| SUTTON, M | 1 |
| LOVE, R; RABSON, AS; WILDY, P | 1 |
| GRANT, AP | 1 |
| GRIEM, ML; MALKINSON, FD | 2 |
| ROBERTSON, MG | 1 |
| ASHENBRUCKER, H; ATHENS, JW; BOGGS, DR; CARTWRIGHT, GE; HAAB, OP; RAAB, SO; WINTROBE, MM | 1 |
| ROOK, A | 1 |
| SETAELAE, K | 1 |
| BUNKER, MC | 1 |
| WILSON, GB | 1 |
| PAOLINO, W | 1 |
| BASTIN, JP; JORIS, H | 1 |
| HAVAS, LJ | 1 |
| BACK, A; BLOCH-FRANKENTHAL, L | 1 |
| LEVINE, M | 1 |
| HIRSCH, H | 1 |
| BACK, A; UYEKI, E; WALASZEK, E | 1 |
| REBERT, AF | 1 |
| Jordan, MA; Wilson, L | 1 |
| SETALA, K | 1 |
| GOLDBERG, B; ORTEGA, LG | 1 |
| BASS, AD; PROBERT, C | 1 |
| Giannakakou, P; Zhou, J | 1 |
| Hayashi, Y; Kiso, Y; Lloyd, GK; Miller, BR; Neuteboom, ST; Nicholson, B; Palladino, MA | 1 |
| Barnes, J; Boudreau, N; Cayer, ML; Conway, D; Heckman, CA; Li, Y; Uppal, SO; Wendt, E | 1 |
| Gillespie, E; Lichtenstein, LM; Schleimer, RP | 1 |
| Ide, T; Ishibashi, S; Nishikawa, K; Tsuji, Y | 1 |
| De Mets, M; Mareel, MM | 1 |
| Malkinson, FD | 1 |
| Schoenlein, PV | 1 |
| Durdik, JM; Henney, CS; Klimpel, G; Tracey, D | 1 |
| Bretscher, MS; Stern, PL | 1 |
| Cox, PJ; Farmer, PB | 1 |
| Shostak, S | 1 |
| Nicolini, C | 1 |
| Juliano, RL | 1 |
| Berlin, RD; Oliver, JM; Ukena, TE; Yin, HH | 1 |
| Koizumi, A; Masuda, H; Tsukada, M; Wada, Y; Weindruch, R | 1 |
| Hu, E; Jeffers, S; Ko, R; Koda, R; Muggia, F; Rosen, P; Scholtz, M | 1 |
| Cornwell, MM; Gottesman, MM; Ling, V; Pastan, I; Riordan, JR; Roninson, IB; Ueda, K | 1 |
| Hamada, H; Oh-hara, T; Okochi, E; Tsuruo, T | 1 |
| Chin, JE; Fojo, A; Gottesman, MM; Pastan, I; Richert, N; Roninson, IB; Shen, DW | 1 |
| Osieka, R | 1 |
| Akiyama, S; Fojo, A; Gottesman, MM; Hanover, JA; Pastan, I | 1 |
| Akiyama, S; Gottesman, MM; Pastan, I; Richert, N; Shen, D | 1 |
| Nichols, WW; Tjio, JH | 1 |
| Kovacs, G | 1 |
| Dendy, PP | 1 |
| Grossetete, JL; Papillon, P | 1 |
| Ove, R | 1 |
| Graves, JA | 1 |
| Henney, CS | 1 |
| Knufermann, H; Wallach, DF; Wunderlich, F | 1 |
| Carpentier, S; Lejeune, J | 1 |
| Greenstein, A; Rapley, LF; Sealy, R; Shepstone, BJ | 1 |
| Sokal, JE; Stutzman, L | 1 |
| Vervel', EM | 1 |
| Creasey, WA; Sartorelli, AC | 1 |
| van Os, FH | 1 |
| Seidenglanz, G | 1 |
| MacGregor, AB; Macleod, DA; Thomson, JW | 1 |
| Liavåg, I | 1 |
| Mendelsohn, ML; Shackney, SE | 1 |
| Domnina, LV; Gelfand, IM; Rappoport, RI; Vasiliev, JM | 1 |
| Suzuki, K | 1 |
34 review(s) available for colchicine and Benign Neoplasms
| Article | Year |
|---|---|
Recent developments on (-)-colchicine derivatives: Synthesis and structure-activity relationship.
Topics: Antineoplastic Agents, Phytogenic; Cell Proliferation; Colchicine; Humans; Molecular Structure; Neoplasms | 2020 |
Recent advances of antitumor shikonin/alkannin derivatives: A comprehensive overview focusing on structural classification, synthetic approaches, and mechanisms of action.
Topics: Antineoplastic Agents; Apoptosis; Humans; Naphthoquinones; Neoplasms | 2022 |
Resin Glycosides from
Topics: Convolvulaceae; Glycosides; Humans; Molecular Structure; Neoplasms; Nuclear Magnetic Resonance, Biomolecular; Oligosaccharides; Resins, Plant; Vinblastine | 2022 |
Mechanistic Insights and Docking Studies of Phytomolecules as Potential Candidates in the Management of Cancer.
Topics: Antineoplastic Agents; Bibenzyls; Colchicine; Curcumin; Humans; Molecular Docking Simulation; Neoplasms; Paclitaxel | 2022 |
Crosstalk between xanthine oxidase (XO) inhibiting and cancer chemotherapeutic properties of comestible flavonoids- a comprehensive update.
Topics: Apigenin; Colchicine; Enzyme Inhibitors; Flavonoids; Humans; Luteolin; Neoplasms; Xanthine Oxidase | 2022 |
Recent Advances of Tubulin Inhibitors Targeting the Colchicine Binding Site for Cancer Therapy.
Topics: Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Proliferation; Colchicine; Humans; Microtubules; Molecular Targeted Therapy; Neoplasms; Tubulin; Tubulin Modulators | 2022 |
Microtubules and Cell Division: Potential Pharmacological Targets in Cancer Therapy.
Topics: Antineoplastic Agents; Colchicine; HeLa Cells; Humans; Microtubules; Mitosis; Neoplasms; Tubulin | 2023 |
Targeting and extending the eukaryotic druggable genome with natural products: cytoskeletal targets of natural products.
Topics: Actins; Animals; Biological Products; Colchicine; Cytoskeleton; Drug Resistance, Neoplasm; Eukaryotic Cells; Genome; Humans; Maytansine; Microtubules; Neoplasms; Nervous System Diseases; Taxoids | 2020 |
Exploratory Review of the Role of Statins, Colchicine, and Aspirin for the Prevention of Radiation-Associated Cardiovascular Disease and Mortality.
Topics: Animals; Aspirin; Cardiotoxicity; Cardiovascular Diseases; Colchicine; Heart Disease Risk Factors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Neoplasms; Radiation Injuries; Radiation-Protective Agents; Radiotherapy; Risk Assessment; Treatment Outcome | 2020 |
Targeting Tubulin-colchicine Site for Cancer Therapy: Inhibitors, Antibody- Drug Conjugates and Degradation Agents.
Topics: Animals; Antineoplastic Agents; Binding Sites; Colchicine; Drug Screening Assays, Antitumor; Humans; Immunoconjugates; Mitosis; Neoplasms; Tubulin; Tubulin Modulators | 2019 |
Tubulin inhibitors: a patent survey.
Topics: Binding Sites; Colchicine; Drug Resistance, Neoplasm; Humans; Neoplasms; Patents as Topic; Taxoids; Tubulin; Tubulin Modulators; Vinca Alkaloids | 2014 |
New ligands of the tubulin colchicine site based on X-ray structures.
Topics: Antineoplastic Agents; Binding Sites; Colchicine; Crystallography, X-Ray; Humans; Indoles; Ligands; Molecular Docking Simulation; Neoplasms; Protein Binding; Structure-Activity Relationship; Tubulin; Tubulin Modulators | 2014 |
An overview on 2-arylquinolin-4(1H)-ones and related structures as tubulin polymerisation inhibitors.
Topics: Antineoplastic Agents; Cell Line, Tumor; Colchicine; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Humans; Microtubules; Mitosis; Naphthyridines; Neoplasms; Quinazolinones; Quinolones; Signal Transduction; Structure-Activity Relationship; Tubulin Modulators | 2014 |
Tubulins - the target for anticancer therapy.
Topics: Antineoplastic Agents, Phytogenic; Binding Sites; Chalcones; Clinical Trials as Topic; Colchicine; Humans; Macrolides; Neoplasms; Paclitaxel; Protein Binding; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Vinca Alkaloids | 2015 |
Tubulin colchicine binding site inhibitors as vascular disrupting agents in clinical developments.
Topics: Antineoplastic Agents; Binding Sites; Colchicine; Humans; Neoplasms; Neovascularization, Pathologic; Tubulin; Tubulin Modulators | 2015 |
Potential anticancer role of colchicine-based derivatives: an overview.
Topics: Animals; Antineoplastic Agents, Phytogenic; Colchicine; Humans; Neoplasms; Structure-Activity Relationship | 2017 |
Novel Colchicine Derivatives and their Anti-cancer Activity.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Colchicine; Drug Screening Assays, Antitumor; Humans; Neoplasms; Tubulin | 2017 |
Microtubule dynamics as a target in oncology.
Topics: Animals; Antineoplastic Agents, Phytogenic; Bridged Bicyclo Compounds, Heterocyclic; Cell Division; Clinical Trials as Topic; Colchicine; Drug Delivery Systems; Drug Screening Assays, Antitumor; Epothilones; Humans; Lactones; Macrolides; Microtubules; Neoplasms; Steroids; Taxoids; Tubulin Modulators; Vinca Alkaloids | 2009 |
Microtubule-binding natural products for cancer therapy.
Topics: Antineoplastic Agents, Phytogenic; Binding Sites; Bridged-Ring Compounds; Clinical Trials as Topic; Colchicine; Epothilones; Humans; Microtubules; Neoplasms; Taxoids; Tubulin Modulators; Vinca Alkaloids | 2010 |
Colchicine semisynthetics: chemotherapeutics for cancer?
Topics: Antimitotic Agents; Colchicine; Drug Delivery Systems; Humans; Liliaceae; Nanomedicine; Neoplasms; Tubulin Modulators | 2013 |
CROSS RESISTANCE AND COLLATERAL SENSITIVITY STUDIES IN CANCER CHEMOTHERAPY.
Topics: Alkylating Agents; Antimetabolites; Antineoplastic Agents; Azaserine; Colchicine; Drug Resistance; Drug Resistance, Microbial; Folic Acid Antagonists; Guanidines; Humans; Leucine; Metabolism; Neoplasms; Neoplasms, Experimental; Pharmacology; Purines; Pyrimidines; Steroids; Tissue Culture Techniques | 1963 |
THE VINCA ALKALOIDS.
Topics: Alkaloids; Antineoplastic Agents; Biomedical Research; Chemistry, Pharmaceutical; Colchicine; Leukemia; Neoplasms; Pharmacology; Research; Vinca Alkaloids; Vincristine | 1964 |
Microtubules as a target for anticancer drugs.
Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Cell Cycle; Colchicine; Drug Resistance, Neoplasm; Drug Synergism; Humans; Microtubules; Neoplasms; Paclitaxel; Spindle Apparatus; Vinca Alkaloids | 2004 |
Targeting microtubules for cancer chemotherapy.
Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Binding Sites; Cell Cycle; Colchicine; Drug Resistance, Neoplasm; Humans; Microtubules; Neoplasms; Noscapine; Taxoids; Tubulin; Vinca Alkaloids | 2005 |
Effect of microtubule inhibitors on invasion and on related activities of tumor cells.
Topics: Animals; Binding Sites; Cell Division; Cell Membrane; Cell Movement; Cell Survival; Colchicine; Microtubules; Neoplasm Invasiveness; Neoplasms; Tubulin | 1984 |
Colchicine. New uses of an old, old drug.
Topics: Colchicine; Familial Mediterranean Fever; Gout; Humans; Inflammation; Neoplasms; Skin Diseases | 1982 |
Role of gene amplification in drug resistance.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cloning, Molecular; Colchicine; DNA, Circular; Drug Resistance, Multiple; Gene Amplification; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Neoplasms; Tumor Cells, Cultured | 1994 |
Towards selectivity? Approaches to the design of new anti-tumour agents--II.
Topics: Altretamine; Amino Acids; Antineoplastic Agents; Carbohydrates; Chelating Agents; Colchicine; Coloring Agents; Dacarbazine; Daunorubicin; Doxorubicin; Drug Interactions; Ellipticines; Folic Acid Antagonists; Heart Diseases; Humans; Lectins; Neoplasms; Nitrosourea Compounds; Peptide Hydrolases; Podophyllotoxin; Polymers; Structure-Activity Relationship | 1977 |
The cell surface.
Topics: Agglutination; Animals; Binding Sites; Cell Membrane; Cell Transformation, Neoplastic; Colchicine; Diffusion; Humans; Lectins; Leukocytes; Ligands; Lipids; Microtubules; Models, Biological; Neoplasms; Phagocytosis; Proteins; Subcellular Fractions; Surface Properties; Terminology as Topic; Vinca Alkaloids | 1975 |
Use of anticancer drugs during pregnancy.
Topics: Alkylating Agents; Aminopterin; Animals; Antimetabolites; Antineoplastic Agents; Busulfan; Chlorambucil; Choriocarcinoma; Colchicine; Female; Fetal Death; Folic Acid Antagonists; Gestational Age; Humans; Mercaptopurine; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Pregnancy; Pregnancy Complications; Urethane; Vinblastine | 1968 |
[Antitumor properties of colchamine (omain)].
Topics: Animals; Cats; Colchicine; Hodgkin Disease; Humans; Leukemia, Myeloid; Mice; Neoplasms; Rats; Skin Neoplasms | 1967 |
Cancer chemotherapy.
Topics: Alkaloids; Amides; Animals; Antineoplastic Agents; Asparaginase; Cell Division; Colchicine; Cytarabine; DNA; Griseofulvin; Humans; Hydroxyurea; Mice; Neoplasms; Nucleosides; Thiosemicarbazones; Vinblastine; Vincristine | 1969 |
[Plants with cytostatic effect].
Topics: Alkaloids; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Nucleus; Cell Transformation, Neoplastic; Colchicine; Colchicum; DNA; Drug Synergism; Glutamine; Glycolysis; Humans; Leukemia; Mercaptopurine; Methotrexate; Mitosis; Neoplasms; Plant Extracts; Plants, Medicinal; Plants, Toxic; Podophyllum; Prednisone; Purines; Pyrimidines; RNA; Steroids; Vincristine | 1970 |
[Chemotherapy of malignant tumors. 44].
Topics: Adrenal Cortex Hormones; Alkylating Agents; Androgens; Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Azirines; Carbamates; Colchicine; Dichlorodiphenyldichloroethane; Esters; Estrogens; Ethers, Cyclic; Ethylamines; Excitatory Amino Acid Antagonists; Folic Acid Antagonists; Heterocyclic Compounds; Hormones; Hydrazines; Mannitol; Neoplasms; Phytotherapy; Pipobroman; Plants, Medicinal; Plants, Toxic; Podophyllum; Purines; Pyrimidines; Sulfonic Acids; Triazines; Vinblastine; Vincristine | 1970 |
198 other study(ies) available for colchicine and Benign Neoplasms
| Article | Year |
|---|---|
BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo.
Topics: Animals; Antineoplastic Agents; Apoptosis; Binding Sites; Cell Division; Cell Line, Tumor; Colchicine; Drug Screening Assays, Antitumor; G2 Phase; Humans; Indoles; KB Cells; Male; Mice; Mice, Nude; Microtubules; Mitochondria; Mitosis; Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Tubulin; Tubulin Modulators; Xenograft Model Antitumor Assays | 2004 |
CHMIS-C: a comprehensive herbal medicine information system for cancer.
Topics: Antineoplastic Agents, Phytogenic; Databases, Factual; Internet; National Institutes of Health (U.S.); Neoplasms; Phytotherapy; Plant Preparations; United States; United States Food and Drug Administration | 2005 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Novel microtubule-interacting phenoxy pyridine and phenyl sulfanyl pyridine analogues for cancer therapy.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Flow Cytometry; Fluorescent Antibody Technique; Humans; Microtubules; Molecular Structure; Neoplasms; Pyridines; Small Molecule Libraries; Stereoisomerism; Structure-Activity Relationship; Tubulin | 2008 |
Synthesis and structure-activity relationships of 2-amino-1-aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents.
Topics: Anisoles; Cell Line, Tumor; Cell Proliferation; Chemistry, Pharmaceutical; Drug Design; Drug Screening Assays, Antitumor; Humans; Indoles; Inhibitory Concentration 50; Models, Chemical; Naphthalenes; Neoplasms; Structure-Activity Relationship; Tubulin; Tubulin Modulators | 2008 |
Synthesis and biological activities of 2-amino-1-arylidenamino imidazoles as orally active anticancer agents.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Fragmentation; Dose-Response Relationship, Drug; Female; Humans; Imidazoles; Inhibitory Concentration 50; Leukemia P388; Mice; Mice, Inbred DBA; Mice, Nude; Microtubules; Models, Chemical; Molecular Structure; Neoplasms; Structure-Activity Relationship; Tubulin; Xenograft Model Antitumor Assays | 2010 |
Discovery of benzimidazole derivatives as novel multi-target EGFR, VEGFR-2 and PDGFR kinase inhibitors.
Topics: Antineoplastic Agents; Benzimidazoles; Cell Proliferation; Drug Discovery; ErbB Receptors; Hep G2 Cells; Humans; Models, Molecular; Neoplasms; Protein Kinase Inhibitors; Receptors, Platelet-Derived Growth Factor; Structure-Activity Relationship; Vascular Endothelial Growth Factor Receptor-2 | 2011 |
Synthesis, biological evaluation, and molecular docking studies of cinnamic acyl 1,3,4-thiadiazole amide derivatives as novel antitubulin agents.
Topics: Amides; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cinnamates; Humans; Neoplasms; Thiadiazoles; Tubulin; Tubulin Modulators | 2012 |
Design, synthesis, biological evaluation and molecular modeling studies of 1-aryl-6-(3,4,5-trimethoxyphenyl)-3(Z)-hexen-1,5-diynes as a new class of potent antitumor agents.
Topics: Alkynes; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Mice; Mice, Nude; Models, Molecular; Molecular Structure; Neoplasms; Structure-Activity Relationship | 2013 |
Synthesis and biological evaluation of novel pyranochalcone derivatives as a new class of microtubule stabilizing agents.
Topics: Animals; Antineoplastic Agents; Benzopyrans; Cell Line; Cell Proliferation; Chalones; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Hep G2 Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Microtubules; Molecular Structure; Neoplasms; Structure-Activity Relationship; Tubulin Modulators | 2013 |
Design, synthesis, and biological evaluation of (E)-N-aryl-2-arylethenesulfonamide analogues as potent and orally bioavailable microtubule-targeted anticancer agents.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Biological Availability; Blood-Brain Barrier; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Drug Design; Drug Resistance, Neoplasm; HCT116 Cells; Humans; K562 Cells; MCF-7 Cells; Mice; Mice, Nude; Microtubules; Neoplasms; Polymerization; Sulfonamides; Tubulin; Tumor Burden; Xenograft Model Antitumor Assays | 2013 |
Design, synthesis and biological evaluation of millepachine derivatives as a new class of tubulin polymerization inhibitors.
Topics: Animals; Antineoplastic Agents; Benzopyrans; Binding Sites; Cell Line, Tumor; Cell Proliferation; Chalcones; Colchicine; Drug Design; Drug Screening Assays, Antitumor; Female; G2 Phase Cell Cycle Checkpoints; Hep G2 Cells; Humans; K562 Cells; M Phase Cell Cycle Checkpoints; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Docking Simulation; Neoplasms; Protein Binding; Protein Structure, Tertiary; Structure-Activity Relationship; Transplantation, Heterologous; Tubulin; Tubulin Modulators | 2013 |
Furanylazaindoles: potent anticancer agents in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Female; Heterocyclic Compounds, 2-Ring; HT29 Cells; Humans; Indoles; Inhibitory Concentration 50; Mice, Nude; Molecular Structure; Neoplasms; Polymerization; Sulfonamides; Tubulin; Xenograft Model Antitumor Assays | 2013 |
New pyrrole derivatives with potent tubulin polymerization inhibiting activity as anticancer agents including hedgehog-dependent cancer.
Topics: Aniline Compounds; Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Membrane Permeability; Cell Proliferation; Cell Survival; Colchicine; Drug Screening Assays, Antitumor; Guanidines; Hedgehog Proteins; Humans; M Phase Cell Cycle Checkpoints; Mice; Molecular Docking Simulation; Neoplasms; Polymerization; Protein Binding; Pyrroles; Signal Transduction; Structure-Activity Relationship; Tubulin; Tubulin Modulators | 2014 |
Design and synthesis of pironetin analogue/colchicine hybrids and study of their cytotoxic activity and mechanisms of interaction with tubulin.
Topics: Antineoplastic Agents; Binding Sites; Cell Proliferation; Colchicine; Drug Design; Fluorescent Antibody Technique; Humans; Microtubules; Molecular Structure; Neoplasms; Pyrones; Structure-Activity Relationship; Tubulin; Tumor Cells, Cultured | 2014 |
Synthesis and biological evaluation of benzimidazole acridine derivatives as potential DNA-binding and apoptosis-inducing agents.
Topics: Acridines; Antineoplastic Agents; Apoptosis; Benzimidazoles; Cell Line, Tumor; DNA; Humans; Intercalating Agents; Neoplasms | 2015 |
Progress Toward the Development of Noscapine and Derivatives as Anticancer Agents.
Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Neoplasms; Noscapine | 2015 |
New Indole Tubulin Assembly Inhibitors Cause Stable Arrest of Mitotic Progression, Enhanced Stimulation of Natural Killer Cell Cytotoxic Activity, and Repression of Hedgehog-Dependent Cancer.
Topics: Animals; Cell Division; Cell Line, Tumor; Cytotoxicity, Immunologic; Drug Resistance, Neoplasm; Hedgehog Proteins; Humans; Indoles; Killer Cells, Natural; Mice; Mitosis; Neoplasms; NIH 3T3 Cells; Tubulin | 2015 |
Discovery of novel 2-phenyl-imidazo[1,2-a]pyridine analogues targeting tubulin polymerization as antiproliferative agents.
Topics: Antineoplastic Agents; Cell Proliferation; Colchicine; Crystallography, X-Ray; HeLa Cells; Humans; Imidazoles; Models, Molecular; Neoplasms; Pyridines; Tubulin; Tubulin Modulators | 2016 |
Tubulin-binding dibenz[c,e]oxepines: Part 2. Structural variation and biological evaluation as tumour vasculature disrupting agents.
Topics: Animals; Cell Line, Tumor; Dibenzoxepins; Dose-Response Relationship, Drug; Heterografts; Humans; Mice; Molecular Structure; Neoplasms; Tubulin | 2017 |
Eco-friendly synthesis of novel cyanopyridine derivatives and their anticancer and PIM-1 kinase inhibitory activities.
Topics: Antineoplastic Agents; Apoptosis; Drug Design; Drug Screening Assays, Antitumor; Green Chemistry Technology; HCT116 Cells; Hep G2 Cells; Humans; MCF-7 Cells; Molecular Docking Simulation; Neoplasms; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-pim-1; Pyridines | 2017 |
Design and characterization of α-lipoic acyl shikonin ester twin drugs as tubulin and PDK1 dual inhibitors.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Drug Design; Glycolysis; HeLa Cells; Humans; Mitosis; Naphthoquinones; Neoplasms; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Tubulin; Tubulin Modulators | 2018 |
Conformational mimetics of the α-methyl chalcone TUB091 binding tubulin: Design, synthesis and antiproliferative activity.
Topics: Animals; Antineoplastic Agents; Benzodioxoles; Binding Sites; Biomimetics; Cell Line; Cell Proliferation; Chalcones; Drug Design; Endothelial Cells; Humans; Neoplasms; Protein Conformation; Tubulin; Tubulin Modulators | 2018 |
Antiproliferative efficacy of curcumin mimics through microtubule destabilization.
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Curcumin; Drug Screening Assays, Antitumor; Female; Humans; Male; Mice; Microtubules; Neoplasms | 2018 |
Novel nicotinoyl pyrazoline derivates bearing N-methyl indole moiety as antitumor agents: Design, synthesis and evaluation.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Drug Design; Female; HEK293 Cells; HeLa Cells; Humans; Indoles; Mice, Nude; Mitosis; Models, Molecular; Neoplasms; Pyrazoles; Tubulin Modulators; Uterine Cervical Neoplasms | 2018 |
Synthesis of 5H-pyrido[3,2-b]pyrrolizin-5-one tripentone analogs with antitumor activity.
Topics: Antineoplastic Agents; Apoptosis; Caco-2 Cells; Cell Line, Tumor; Drug Screening Assays, Antitumor; HCT116 Cells; Humans; MCF-7 Cells; Neoplasms; Pyridines; Pyrroles; Structure-Activity Relationship | 2018 |
Design, synthesis and biological evaluation of benzoylacrylic acid shikonin ester derivatives as irreversible dual inhibitors of tubulin and EGFR.
Topics: A549 Cells; Acrylates; Animals; Antineoplastic Agents; Apoptosis; Benzoates; Drug Design; ErbB Receptors; Humans; Mice, Nude; Molecular Docking Simulation; Naphthoquinones; Neoplasms; Tubulin; Tubulin Modulators | 2019 |
Design, synthesis and anticancer properties of isocombretapyridines as potent colchicine binding site inhibitors.
Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Binding Sites; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Design; G2 Phase Cell Cycle Checkpoints; Humans; Membrane Potential, Mitochondrial; Mice; Molecular Docking Simulation; Molecular Structure; Neoplasms; Protein Binding; Pyridines; Structure-Activity Relationship; Tubulin; Tubulin Modulators | 2020 |
Discovery of a chiral fluorinated azetidin-2-one as a tubulin polymerisation inhibitor with potent antitumour efficacy.
Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Azetidines; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Stability; G2 Phase Cell Cycle Checkpoints; Humans; Mice; Microsomes, Liver; Molecular Docking Simulation; Molecular Structure; Neoplasms; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Xenograft Model Antitumor Assays | 2020 |
Discovery of dihydrofuranoallocolchicinoids - Highly potent antimitotic agents with low acute toxicity.
Topics: Animals; Antimitotic Agents; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colchicine; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Furans; Humans; Mice, Inbred BALB C; Mice, Inbred C57BL; Molecular Docking Simulation; Neoplasms; Tubulin; Tubulin Modulators | 2020 |
Design, Synthesis, and Bioactivity Evaluation of Dual-Target Inhibitors of Tubulin and Src Kinase Guided by Crystal Structure.
Topics: Acetamides; Animals; Antineoplastic Agents; Cattle; Cell Line, Tumor; Chickens; Crystallography, X-Ray; Drug Design; Female; G2 Phase Cell Cycle Checkpoints; Humans; Male; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Morpholines; Neoplasms; Protein Binding; Protein Kinase Inhibitors; Pyridines; Rats, Sprague-Dawley; Signal Transduction; src-Family Kinases; Structure-Activity Relationship; Tubulin; Tubulin Modulators | 2021 |
Structure-Based Design and Synthesis of N-Substituted 3-Amino-β-Carboline Derivatives as Potent αβ-Tubulin Degradation Agents.
Topics: Animals; Antineoplastic Agents; Apoptosis; Binding Sites; Carbolines; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; G2 Phase Cell Cycle Checkpoints; Humans; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Neoplasms; Protein Binding; Rats; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Xenograft Model Antitumor Assays | 2022 |
Discovery of a Novel Stilbene Derivative as a Microtubule Targeting Agent Capable of Inducing Cell Ferroptosis.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Ferroptosis; Humans; Microtubules; Neoplasms; Stilbenes | 2022 |
A novel aromatic amide derivative SY-65 co-targeted tubulin and histone deacetylase 1 with potent anticancer activity in vitro and in vivo.
Topics: Amides; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colchicine; Drug Screening Assays, Antitumor; Epigenesis, Genetic; Histone Deacetylase 1; Humans; Molecular Docking Simulation; Neoplasms; Structure-Activity Relationship; Tubulin; Tubulin Modulators | 2022 |
Targeted delivery of a colchicine analogue provides synergy with ATR inhibition in cancer cells.
Topics: Apoptosis; Ataxia Telangiectasia Mutated Proteins; Cell Line, Tumor; Colchicine; G2 Phase Cell Cycle Checkpoints; Matrix Metalloproteinase 14; Neoplasms; Prodrugs; Protein Kinase Inhibitors | 2022 |
Structural Perspective of Benzophenones Targeting Tubulin as Anticancer Agents.
Topics: Antineoplastic Agents; Benzophenones; Colchicine; Humans; Molecular Docking Simulation; Neoplasms; Tubulin | 2023 |
Nanofabrication of PLGA-PEG-chitosan-folic acid systems for delivery of colchicine to HT-29 cancer cells.
Topics: Antioxidants; Chitosan; Colchicine; Drug Carriers; Folic Acid; Humans; Nanoparticles; Neoplasms; Particle Size; Polylactic Acid-Polyglycolic Acid Copolymer | 2023 |
Imidazo[4,5-b]pyridine derived tubulin polymerization inhibitors: Design, synthesis, biological activity in vitro and computational analysis.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colchicine; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Neoplasms; Polymerization; Pyridines; Structure-Activity Relationship; Tubulin; Tubulin Modulators | 2022 |
Consensus Virtual Screening Protocol Towards the Identification of Small Molecules Interacting with the Colchicine Binding Site of the Tubulin-microtubule System.
Topics: Antineoplastic Agents; Binding Sites; Cell Proliferation; Colchicine; Consensus; Humans; Microtubules; Molecular Docking Simulation; Neoplasms; Tubulin; Tubulin Modulators | 2023 |
ID-Checker Technology for the Highly Selective Macroscale Delivery of Anticancer Agents to the Cancer Cells.
Topics: Antineoplastic Agents; Colchicine; Glucose; Glucose Transport Proteins, Facilitative; Glucose Transporter Type 1; Neoplasms; Technology | 2022 |
Development of [1,2]oxazoloisoindoles tubulin polymerization inhibitors: Further chemical modifications and potential therapeutic effects against lymphomas.
Topics: Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Colchicine; Humans; Isoindoles; Lymphoma; Neoplasms; Structure-Activity Relationship; Tubulin; Tubulin Modulators | 2022 |
Replacing the tropolonic methoxyl group of colchicine with methylamino increases tubulin binding affinity with improved therapeutic index and overcomes paclitaxel cross-resistance.
Topics: Antineoplastic Agents; Cell Line, Tumor; Colchicine; Humans; Neoplasms; Paclitaxel; Tubulin; Vincristine | 2023 |
Systematic Studies on Anti-Cancer Evaluation of Stilbene and Dibenzo[
Topics: Antineoplastic Agents; Binding Sites; Cell Proliferation; Colchicine; HEK293 Cells; Humans; Microtubules; Neoplasms; Oxepins; Stilbenes; Tubulin; Tubulin Modulators | 2023 |
Reversal of P-glycoprotein-mediated multidrug resistance by natural N-alkylated indole alkaloid derivatives in KB-ChR-8-5 drug-resistant cancer cells.
Topics: Adenosine Triphosphate; Alkaloids; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cell Line, Tumor; Colchicine; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Indole Alkaloids; Neoplasms | 2023 |
4(1H)-quinolone derivatives overcome acquired resistance to anti-microtubule agents by targeting the colchicine site of β-tubulin.
Topics: Antineoplastic Agents; Apoptosis; Binding Sites; Cell Proliferation; Colchicine; Drug Resistance, Neoplasm; Humans; Molecular Docking Simulation; Neoplasms; Quinolones; Tubulin; Tubulin Modulators | 2019 |
Synthesis, biological evaluation and molecular docking studies of new amides of 4-chlorothiocolchicine as anticancer agents.
Topics: Amides; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colchicine; Drug Design; Drug Screening Assays, Antitumor; Halogenation; Humans; Molecular Docking Simulation; Neoplasms; Tubulin Modulators | 2020 |
CPPF, A Novel Microtubule Targeting Anticancer Agent, Inhibits the Growth of a Wide Variety of Cancers.
Topics: A549 Cells; Animals; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colchicine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; HeLa Cells; Hep G2 Cells; Humans; Jurkat Cells; K562 Cells; Male; MCF-7 Cells; Mice; Microtubules; Mitosis; Neoplasms; Paclitaxel; PC-3 Cells; U937 Cells; Xenograft Model Antitumor Assays; Zebrafish | 2020 |
A novel orally active microtubule destabilizing agent S-40 targets the colchicine-binding site and shows potent antitumor activity.
Topics: A549 Cells; Administration, Oral; Animals; Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colchicine; Crystallography, X-Ray; Humans; Male; Mice; Models, Molecular; Neoplasms; Paclitaxel; Protein Conformation; Tubulin; Tubulin Modulators; Xenograft Model Antitumor Assays | 2020 |
Effect of Anti-Inflammatory Drugs on Clinical Outcomes in Patients With Malignant Pericardial Effusion.
Topics: Aged; Colchicine; Female; Humans; Incidence; Male; Middle Aged; Neoplasms; Pericardial Effusion; Pericardiocentesis; Pericarditis, Constrictive; Republic of Korea; Retrospective Studies | 2020 |
Recurrent pericarditis: an update on diagnosis and management.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Colchicine; Humans; Inflammation; Neoplasms; Pericarditis; Pharmaceutical Preparations; Recurrence | 2021 |
Discovery of novel N-benzylbenzamide derivatives as tubulin polymerization inhibitors with potent antitumor activities.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzamides; Binding Sites; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colchicine; Drug Design; Drug Screening Assays, Antitumor; Humans; Mice; Mice, Inbred ICR; Molecular Docking Simulation; Neoplasms; Neovascularization, Physiologic; Structure-Activity Relationship; Tubulin; Tubulin Modulators | 2021 |
Identification of novel αβ-tubulin modulators with antiproliferative activity directed to cancer therapy using ligand and structure-based virtual screening.
Topics: Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colchicine; Computer Simulation; Drug Screening Assays, Antitumor; Hep G2 Cells; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Neoplasms; Structure-Activity Relationship; Tubulin; Tubulin Modulators | 2020 |
The role of Colchicine on actin polymerization dynamics: as a potent anti-angiogenic factor.
Topics: Actins; Colchicine; Endothelial Cells; Humans; Microtubules; Neoplasms; Polymerization; Tubulin | 2022 |
Quinolin-6-Yloxyacetamides Are Microtubule Destabilizing Agents That Bind to the Colchicine Site of Tubulin.
Topics: Animals; Antineoplastic Agents; Cattle; Cell Line, Tumor; Cell Proliferation; Colchicine; Humans; Molecular Docking Simulation; Neoplasms; Quinolines; Tubulin; Tubulin Modulators | 2017 |
Sweet syndrome in patients with and without malignancy: A retrospective analysis of 83 patients from a tertiary academic referral center.
Topics: Academic Medical Centers; Adrenal Cortex Hormones; Adult; Aged; Anemia; Arthralgia; Colchicine; Dapsone; Female; Filgrastim; fms-Like Tyrosine Kinase 3; Folic Acid Antagonists; Hematologic Agents; Humans; Inflammation; Leukemia, Myeloid, Acute; Leukopenia; Male; Middle Aged; Mutation; Neoplasms; Nuclear Proteins; Nucleophosmin; Potassium Iodide; Retrospective Studies; Sweet Syndrome; Tertiary Care Centers; Thrombocytopenia; Tubulin Modulators | 2018 |
SKLB060 Reversibly Binds to Colchicine Site of Tubulin and Possesses Efficacy in Multidrug-Resistant Cell Lines.
Topics: Animals; Antineoplastic Agents; Apoptosis; Binding Sites; Cell Line, Tumor; Colchicine; Coumarins; Drug Resistance, Neoplasm; Female; G2 Phase Cell Cycle Checkpoints; Humans; Mice; Mice, Inbred BALB C; Mice, Knockout; Molecular Docking Simulation; Neoplasms; Protein Binding; Transplantation, Heterologous; Tubulin; Tubulin Modulators | 2018 |
Design and synthesis of novel 5-(4-chlorophenyl)furan derivatives with inhibitory activity on tubulin polymerization.
Topics: Antineoplastic Agents; Binding Sites; Cell Cycle; Cell Line, Tumor; Colchicine; Drug Design; Drug Screening Assays, Antitumor; Furans; Halogenation; Humans; Leukemia; Molecular Docking Simulation; Neoplasms; Polymerization; Tubulin; Tubulin Modulators | 2018 |
Chemoresistance of cancer floating cells is independent of their ability to form 3D structures: Implications for anticancer drug screening.
Topics: Antibodies; Antigens, CD; Antineoplastic Agents; Cadherins; Cell Adhesion; Cell Culture Techniques; Cell Survival; Colchicine; Culture Media, Serum-Free; Drug Resistance, Neoplasm; Female; Humans; Hydroxyurea; Indoles; Male; MCF-7 Cells; Neoplasms; PC-3 Cells; Phenotype; Pyrroles; Spheroids, Cellular | 2019 |
Synthesis, antiproliferative activity and molecular docking of thiocolchicine urethanes.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colchicine; Drug Design; Drug Screening Assays, Antitumor; Humans; Mitosis; Models, Molecular; Molecular Docking Simulation; Neoplasms; Tubulin; Tubulin Modulators; Urethane | 2018 |
Design, synthesis and biological evaluation of quinoline-indole derivatives as anti-tubulin agents targeting the colchicine binding site.
Topics: Animals; Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Colchicine; Drug Design; Drug Screening Assays, Antitumor; Heterografts; Humans; Indoles; K562 Cells; Neoplasms; Quinolines; Structure-Activity Relationship; Tubulin; Tubulin Modulators | 2019 |
Update in rheumatology: evidence published in 2012.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antirheumatic Agents; Antiviral Agents; Arthritis; Arthritis, Gouty; Arthritis, Rheumatoid; Autoimmune Diseases; Bacterial Infections; Calcitonin; Colchicine; Cryoglobulinemia; Death, Sudden, Cardiac; Drug Resistance, Viral; Enzyme Inhibitors; Female; Gout; Gout Suppressants; Hand Joints; Hepatitis C, Chronic; Humans; Hyperuricemia; Immunologic Factors; Janus Kinase 3; Male; Myocardial Infarction; Neoplasms; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Practice Guidelines as Topic; Protein Precursors; Pyrimidines; Pyrroles; Registries; Tumor Necrosis Factor-alpha | 2013 |
PD173074, a selective FGFR inhibitor, reverses ABCB1-mediated drug resistance in cancer cells.
Topics: Adenosine Triphosphate; Affinity Labels; Allosteric Regulation; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Line, Tumor; Colchicine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; HEK293 Cells; Humans; Hydrolysis; Neoplasm Proteins; Neoplasms; Paclitaxel; Protein Kinase Inhibitors; Pyrimidines; Receptors, Fibroblast Growth Factor; Recombinant Proteins; Tubulin Modulators; Vincristine | 2013 |
Synthesis, antitubulin, and antiproliferative SAR of C3/C1-substituted tetrahydroisoquinolines.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colchicine; Female; Humans; Male; Mice; Mice, Nude; Multiple Myeloma; Neoplasms; Stereoisomerism; Structure-Activity Relationship; Tetrahydroisoquinolines; Tubulin; Tubulin Modulators | 2014 |
Tumor-targeted prodrug ICT2588 demonstrates therapeutic activity against solid tumors and reduced potential for cardiovascular toxicity.
Topics: Animals; Antineoplastic Agents; Cardiovascular System; Colchicine; Female; Humans; Mice; Mice, Inbred BALB C; Neoplasms; Oligopeptides; Prodrugs; von Willebrand Factor | 2014 |
Molecular insight of isotypes specific β-tubulin interaction of tubulin heterodimer with noscapinoids.
Topics: Binding Sites; Cell Proliferation; Colchicine; Humans; Neoplasms; Noscapine; Protein Binding; Protein Isoforms; Protein Multimerization; Tubulin | 2014 |
Development of a novel class of tubulin inhibitor from desmosdumotin B with a hydroxylated bicyclic B-ring.
Topics: Antineoplastic Agents; Cell Cycle Checkpoints; Cell Proliferation; Colchicine; Drug Discovery; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flavones; Fluorescent Antibody Technique; Humans; Hydroxylation; Microtubules; Models, Molecular; Molecular Structure; Neoplasms; Protein Binding; Protein Conformation; Spindle Apparatus; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Tumor Cells, Cultured | 2015 |
Colchicine Significantly Reduces Incident Cancer in Gout Male Patients: A 12-Year Cohort Study.
Topics: Adult; Case-Control Studies; Cohort Studies; Colchicine; Gout; Gout Suppressants; Humans; Hyperlipidemias; Hypertension; Incidence; Male; Middle Aged; Neoplasms; Obesity; Proportional Hazards Models; Risk Factors; Taiwan | 2015 |
Sweet's syndrome: a retrospective study of 90 cases from a tertiary care center.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blister; Child; Child, Preschool; Colchicine; Cytomegalovirus Infections; Female; Gout Suppressants; Hand Dermatoses; Humans; Inflammatory Bowel Diseases; Lower Extremity; Male; Middle Aged; Neoplasms; Pregnancy; Pregnancy Complications; Retrospective Studies; Sweet Syndrome; Tertiary Care Centers; Upper Extremity; Young Adult | 2016 |
QSAR Modeling of the Arylthioindole Class of Colchicine Polymerization Inhibitors as Anticancer Agents.
Topics: Algorithms; Antineoplastic Agents; Colchicine; Computer-Aided Design; Drug Discovery; Humans; Indoles; Neoplasms; Quantitative Structure-Activity Relationship; Tubulin; Tubulin Modulators | 2017 |
Theoretical and experimental study of polycyclic aromatic compounds as β-tubulin inhibitors.
Topics: Binding Sites; Colchicine; HeLa Cells; Humans; Ligands; Molecular Docking Simulation; Molecular Dynamics Simulation; Neoplasms; Polycyclic Aromatic Hydrocarbons; Small Molecule Libraries; Structure-Activity Relationship; Tubulin; Tubulin Modulators; User-Computer Interface | 2017 |
Factors determining the action of colchicine on tumour growth.
Topics: Colchicine; Neoplasms | 1948 |
The colchicine-X-ray association in cancer treatment-preliminary note.
Topics: Colchicine; Humans; Neoplasms | 1948 |
About the colchicine-roentgentherapy association in the treatment of malignant tumors.
Topics: Colchicine; Neoplasms | 1948 |
Colchicine and radiotherapy treatment of cancer.
Topics: Colchicine; Neoplasms | 1948 |
A pharmacodynamic action test of colchicine as a drug likely to act in cancer; action on cytoplasmic cyclosis.
Topics: Colchicine; Cytoplasm; Neoplasms | 1947 |
Mitotic response to colchicine in human cancer.
Topics: Cell Division; Colchicine; Neoplasms | 1947 |
Chemotherapeutic agents targeting the tubulin cytoskeleton modify LPS-induced cytokine secretion by dendritic cells and increase antigen presentation.
Topics: Antigen Presentation; Antineoplastic Agents; Cells, Cultured; Colchicine; Cytokines; Cytoskeleton; Dendritic Cells; Drug Interactions; Humans; Lipopolysaccharides; Lymphocyte Activation; Neoplasms; NF-kappa B; Paclitaxel; T-Lymphocytes; Tubulin | 2010 |
Quantitative analysis of the effect of tubulin isotype expression on sensitivity of cancer cell lines to a set of novel colchicine derivatives.
Topics: Antineoplastic Agents; Cell Line, Tumor; Colchicine; Drug Design; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Neoplasms; Protein Isoforms; Tubulin; Tubulin Modulators | 2010 |
Thiocolchicoside exhibits anticancer effects through downregulation of NF-κB pathway and its regulated gene products linked to inflammation and cancer.
Topics: Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Colchicine; Down-Regulation; Electrophoretic Mobility Shift Assay; Humans; Inflammation; Neoplasms; NF-kappa B; Signal Transduction | 2010 |
Disruption of microtubules sensitizes the DNA damage-induced apoptosis through inhibiting nuclear factor κB (NF-κB) DNA-binding activity.
Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Caspases; Cell Line; Colchicine; DNA; DNA Damage; Doxorubicin; Humans; Mice; Microtubules; Neoplasms; NF-kappa B; Nocodazole; Protein Binding; Signal Transduction; Tubulin Modulators; Vinblastine | 2010 |
Free tubulin modulates mitochondrial membrane potential in cancer cells.
Topics: Adenosine Triphosphate; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Membrane; Colchicine; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic CMP; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Liver Neoplasms; Male; Membrane Potential, Mitochondrial; Membrane Potentials; Microtubules; Mitochondria, Liver; Neoplasms; Nocodazole; Paclitaxel; Rats; Rats, Sprague-Dawley; Rhodamines; Rotenone; Tubulin | 2010 |
Synthesis and antitumor evaluation of nitrovinyl biphenyls: anticancer agents based on allocolchicines.
Topics: Antineoplastic Agents; Aurora Kinase B; Aurora Kinases; Biphenyl Compounds; Cell Division; Cell Line, Tumor; Colchicine; Cyclin B1; Drug Screening Assays, Antitumor; G2 Phase; Humans; Neoplasms; Protein Serine-Threonine Kinases; Tubulin; Tubulin Modulators | 2011 |
Molecular modelling and competition binding study of Br-noscapine and colchicine provide insight into noscapinoid-tubulin binding site.
Topics: Animals; Antineoplastic Agents; Antitussive Agents; Binding Sites; Colchicine; Goats; Humans; Models, Chemical; Molecular Dynamics Simulation; Molecular Structure; Neoplasms; Noscapine; Protein Conformation; Tubulin | 2011 |
Molecular modelling studies on Arylthioindoles as potent inhibitors of tubulin polymerization.
Topics: Antineoplastic Agents; Binding Sites; Colchicine; Humans; Indoles; Microtubules; Models, Chemical; Molecular Dynamics Simulation; Neoplasms; Polymerization; Protein Binding; Software; Structure-Activity Relationship; Sulfhydryl Compounds; Tubulin; Tubulin Modulators | 2011 |
Synthesis and antitumor molecular mechanism of agents based on amino 2-(3',4',5'-trimethoxybenzoyl)benzo[b]furan: inhibition of tubulin and induction of apoptosis.
Topics: Animals; Anisoles; Antineoplastic Agents; Apoptosis; Benzofurans; Binding Sites; Caspases; Cell Cycle Checkpoints; Cell Line, Tumor; Colchicine; Humans; Mice; Neoplasms; Tubulin; Tubulin Modulators | 2011 |
Triterpenes and a triterpene glucoside from Dysoxylum cumingianum.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Colchicine; Drug Resistance, Multiple; Glucosides; Humans; Meliaceae; Molecular Structure; Neoplasms; Phytotherapy; Plant Extracts; Plant Leaves; Triterpenes; Tubulin Modulators | 2011 |
3-substituted 2-phenylimidazo[2,1-b]benzothiazoles: synthesis, anticancer activity, and inhibition of tubulin polymerization.
Topics: Antineoplastic Agents; Benzothiazoles; Binding Sites; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colchicine; Computer Simulation; Drug Screening Assays, Antitumor; Humans; Imidazoles; Neoplasms; Polymerization; Protein Structure, Tertiary; Structure-Activity Relationship; Tubulin; Tubulin Modulators | 2012 |
Orally bioavailable tubulin antagonists for paclitaxel-refractory cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Binding Sites; Biological Availability; Caco-2 Cells; Cell Line, Tumor; Colchicine; Docetaxel; Dogs; Drug Interactions; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Indoles; Male; Mice; Mice, Inbred ICR; Mice, Nude; Neoplasms; Paclitaxel; Polymerization; Rats; Rats, Sprague-Dawley; Taxoids; Tubulin; Tubulin Modulators | 2012 |
Integrating constitutive gene expression and chemoactivity: mining the NCI60 anticancer screen.
Topics: Algorithms; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cluster Analysis; Colchicine; Computational Biology; Cyclin-Dependent Kinases; Dasatinib; Databases, Genetic; Fluorouracil; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Neoplasms; Oligonucleotide Array Sequence Analysis; Paclitaxel; Pimozide; Purines; Pyrimidines; Terfenadine; Thiazoles; Tubulin Modulators; Verapamil | 2012 |
Characterization of nuclear betaII-tubulin in tumor cells: a possible novel target for taxol.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Nucleolus; Cell Nucleus; Colchicine; Dimerization; Dose-Response Relationship, Drug; Female; Fluorescent Dyes; Humans; Neoplasms; Nocodazole; Nucleolin; Paclitaxel; Phosphoproteins; Protein Isoforms; Rats; RNA-Binding Proteins; Tubulin; Tumor Cells, Cultured | 2002 |
VMN/LHA functional inhibition in tumor-bearing rats suggests hypothalamic involvement in cancer anorexia.
Topics: Animals; Anorexia; Colchicine; Eating; Hypothalamus; Hypothalamus, Middle; Male; Methylcholanthrene; Microinjections; Neoplasm Transplantation; Neoplasms; Rats; Rats, Inbred F344; Sarcoma, Experimental | 2002 |
[Modern trends in chemotherapy of tumors].
Topics: Colchicine; Ethers; Folic Acid Antagonists; Hormones; Humans; Mechlorethamine; Mitosis; Neoplasms; Nitrogen Mustard Compounds; Pentamidine; Podophyllin; Poisons; Steroids; Stilbenes; Urethane | 1952 |
[Action of colchicine associated with radiotherapy in the treatment of malignant tumors].
Topics: Colchicine; Humans; Neoplasms; Radiotherapy | 1953 |
Studies with radioactive Colchicine. I. The influence of tumors on the tissue distribution of radioactive colchicine in mice.
Topics: Animals; Colchicine; Mice; Neoplasms; Tissue Distribution | 1953 |
A cytological study of colchicine-induced nodal tumors in Tradescantia.
Topics: Animals; Colchicine; Neoplasms; Neoplasms, Experimental; Plants; Tradescantia | 1953 |
[Prevention of propagation and metastasis of tumor cells after surgery or biopsy; cytostatic protection of surgery].
Topics: Biopsy; Colchicine; Cytostatic Agents; Humans; Mechlorethamine; Neoplasms; Nitrogen Mustard Compounds | 1953 |
[Chemotherapy of cancer; association of colchicine and radiotherapy, presentation of data on remote results, comparative studies with other chemotherapeutic agents, and considerations on the present state of the problem].
Topics: Antineoplastic Agents; Colchicine; Humans; Neoplasms; Radiotherapy | 1953 |
[Personal experiences with a new alkaloid extract of Colchicum autumnale].
Topics: Alkaloids; Antineoplastic Agents; Colchicine; Colchicum; Humans; Neoplasms | 1954 |
[Study with radiophosphorus on the effect of inhibiting substance on duplication rate and phosphate uptake by tumors].
Topics: Acridines; Antineoplastic Agents; Colchicine; Coloring Agents; Neoplasms; Phosphates; Phosphorus; Phosphorus Radioisotopes; Phosphorus, Dietary | 1954 |
[The use of deacetyl-N-methylcolchicine in the treatment of leukemia, other blood diseases and some neoplasms].
Topics: Colchicine; Demecolcine; Hematologic Diseases; Leukemia; Neoplasms | 1955 |
[Initial results in the use in cancer chemotherapy of a colchicine derivative: N-deacetylthiocolchicine].
Topics: Antineoplastic Agents; Colchicine; Humans; Neoplasms | 1955 |
[Effect of compounds having unsaturated seven membered ring structure on Yoshida sarcoma. IV. Appendix: with two cases of clinical application of colchicine-derivatives].
Topics: Animals; Antineoplastic Agents; Appendix; Colchicine; Humans; Neoplasms; Neoplasms, Experimental; Prostheses and Implants; Sarcoma, Yoshida | 1955 |
[New experiences with demecolcine (colcemide Ciba) in the treatment of leukoses and tumors].
Topics: Colchicine; Demecolcine; Leukemia; Leukemia, Myeloid; Neoplasms | 1955 |
[Combined colchicine-roentgen therapy of cancer].
Topics: Colchicine; Humans; Neck; Neoplasms; Pharynx; Radiotherapy; Staining and Labeling | 1955 |
[Antitumoral action of a hypotoxic derivative of colchicine: deacetylthiocolchicine; clinical aspects and first therapeutic results: 16 case reports].
Topics: Antineoplastic Agents; Colchicine; Humans; Neoplasms | 1955 |
[Some problems in treatment of malignant tumors with cytostatic substances as demonstrated with colcemid].
Topics: Antineoplastic Agents; Colchicine; Cytostatic Agents; Demecolcine; Neoplasms | 1955 |
[Preliminary research on the combined action of alpha-aminoketone and colchicine on growth of a transplanted tumor of mice].
Topics: Animals; Colchicine; Ketones; Mice; Neoplasm Transplantation; Neoplasms; Physiological Phenomena; Research | 1956 |
Assay of cytostatica (colcemid CIBA) in the blood and urine of cancer patients by a tissue culture method.
Topics: Biological Assay; Body Fluids; Colchicine; Demecolcine; Neoplasms; Tissue Culture Techniques | 1956 |
[Effects of a para-alkaloid of Colchicum autumnale on Galliera sarcoma of the rat].
Topics: Alkaloids; Animals; Colchicine; Colchicum; Neoplasms; Neoplasms, Experimental; Rats; Sarcoma | 1956 |
[Indications for combined therapy of malignant tumors with radiotherapy and colcemid].
Topics: Breast; Breast Neoplasms; Colchicine; Demecolcine; Humans; Neoplasms; Radiotherapy | 1956 |
Clinical and experimental study of cancer (especially about the colchicine derivatives and the imido compounds).
Topics: Animals; Antineoplastic Agents; Colchicine; Neoplasms; Neoplasms, Experimental | 1956 |
[De-acetyl-colchicine in antiblastic therapy].
Topics: Colchicine; Humans; Neoplasms | 1957 |
[Use of the combination of small intravenous doses of ACTH and de-acetyl-colchicine in antineoplastic therapy].
Topics: Adrenocorticotropic Hormone; Antineoplastic Agents; Colchicine; Humans; Neoplasms | 1957 |
[Cortisone and adenine as protective drugs for leukocytes in deacetyl-colchicine cytostatic therapy].
Topics: Adenine; Colchicine; Cortisone; Humans; Leukocytes; Neoplasms; Protective Agents | 1957 |
[Combined colchicine-x-ray treatment of cancer].
Topics: Colchicine; Laryngeal Neoplasms; Larynx; Neoplasms; Pharyngeal Neoplasms; Pharynx; Radiotherapy; X-Ray Therapy; X-Rays | 1957 |
[N-desacetyl-thiocolchicine in antitumor chemotherapy].
Topics: Colchicine; Leukemia; Leukemia, Myeloid; Neoplasms; Skin Neoplasms | 1957 |
[The local effects of an antimitotic (substance F) on malignant tumors of the uterine cervix and vulva].
Topics: Antimitotic Agents; Colchicine; Female; Humans; Neoplasms; Stigmasterol; Uterine Cervical Neoplasms; Vulvar Neoplasms | 1956 |
[Presentation of some demonstrative evidence on the results of tumor therapy by desoxyribonucleic acid and thiocolchicine; positive balance of desoxyribonucleic acid].
Topics: Colchicine; DNA; Humans; Neoplasms | 1957 |
[New results in chemotherapy of inoperable cancer cases by colchicin and its derivatives].
Topics: Colchicine; Humans; Neoplasms | 1958 |
[Effect of associated dl-dihydrosarcomycin and omaine on Ehrlich ascites sarcoma].
Topics: Animals; Anti-Bacterial Agents; Ascites; Colchicine; Neoplasms; Neoplasms, Experimental; Sarcoma | 1958 |
[On the induction of resistance to colchicine in heterologous tumors in the golden hamster].
Topics: Animals; Biochemical Phenomena; Colchicine; Cricetinae; Mesocricetus; Neoplasms; Neoplasms, Experimental | 1960 |
[Ionization of digestive cancer].
Topics: Colchicine; Digestive System Neoplasms; Gastrointestinal Neoplasms; Gastrointestinal Tract; Neoplasms | 1960 |
[Tumor-induction in Cuscuta gronovii Willd plantlet by colchicine and by a tegmental inhibitor of germination and growth. A need for "conditioning")].
Topics: Biological Phenomena; Colchicine; Cuscuta; Germination; Neoplasms; Physiological Phenomena; Plants | 1960 |
[Cytological and karyological observations of the effects of nitromin and demecolcin on tumor cells].
Topics: Colchicine; Mechlorethamine; Neoplasms; Nitrogen Mustard Compounds | 1962 |
Preliminary clinical experience with trimethylcolchicinic acid methyl ether d-tartrate (TMCA) in various malignancies.
Topics: Antineoplastic Agents; Colchicine; Humans; Neoplasms; Tartrates | 1963 |
[2 OR 3 PROBLEMS IN THE USE OF THE YOSHIDA SARCOMA AS A TOOL IN A SCREENING TEST FOR ANTICANCER AGENTS].
Topics: Animals; Antineoplastic Agents; Colchicine; Neoplasms; Pharmacology; Pyrimidines; Research; Sarcoma; Sarcoma, Yoshida; Vinblastine | 1963 |
EFFECTS OF MALIGNANT EFFUSIONS ON THE MITOTIC INDEX OF L STRAIN MOUSE CELLS GROWN IN TISSUE CULTURE.
Topics: Animals; Cell Division; Clone Cells; Colchicine; Cytodiagnosis; Exudates and Transudates; Humans; Mice; Mitotic Index; Neoplasms; Pleural Effusion; Pleural Effusion, Malignant; Research; Tissue Culture Techniques | 1963 |
[EVALUATION OF THE CURRENT THERAPEUTIC TRENDS IN HODGKIN'S DISEASE. CRITICAL REVIEW AND CASUISTIC CONTRIBUTION].
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antineoplastic Agents; Aziridines; Bone Marrow Transplantation; Colchicine; Cyclophosphamide; Dactinomycin; Hodgkin Disease; Mechlorethamine; Melphalan; Neoplasms; Radioisotopes; Radiotherapy, High-Energy; Triethylenemelamine; Vinblastine | 1963 |
DRUGS OF CURRENT USE FOR THE TREATMENT OF CANCER AND ALLIED DISEASES.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antineoplastic Agents; Aziridines; Busulfan; Colchicine; Dactinomycin; Diethylstilbestrol; Estrogens; Fluorouracil; Gonadal Steroid Hormones; Mercaptopurine; Methotrexate; Mitomycin; Mitomycins; Neoplasms; Podophyllum; Progestins; Quinones; Thiotepa; Triethylenemelamine; Urethane; Vinblastine | 1963 |
[CARCINOMA OF THE ENDOMETRIUM. TREATMENT].
Topics: Colchicine; Endometrium; Female; Humans; Hysterectomy; Lucanthone; Lymph Node Excision; Neoplasms; Progesterone; Radium; Surgical Procedures, Operative; Uterine Neoplasms | 1963 |
ADENOCARCINOMA OF THE CARDIOESOPHAGEAL JUNCTION.
Topics: Adenocarcinoma; Cardia; Colchicine; Cytodiagnosis; Esophageal Neoplasms; Esophagogastric Junction; Gastrectomy; Humans; Liver Neoplasms; Lymphatic Metastasis; Neoplasms; Pathology; Stomach Neoplasms; Surgical Procedures, Operative | 1964 |
[FURTHER COMPARATIVE STUDIES OF 2 ISOGENIC LINES OF CELLS OF AUTOLOGOUS ORIGIN, INCLUDING 1 TUMORIGENIC LINE].
Topics: Carbohydrate Metabolism; Chromosomes; Colchicine; Cortisone; Genetics; Glucose; Mice; Neoplasms; Neoplasms, Experimental; Pharmacology; Research; Tissue Culture Techniques; Trypsin | 1963 |
[EARLY DIAGNOSIS AND MEDICAL THERAPY OF MALIGNANT TUMORS].
Topics: Antineoplastic Agents; Busulfan; Colchicine; Early Diagnosis; Hodgkin Disease; Mechlorethamine; Mercaptopurine; Neoplasms; Phenylalanine; Podophyllum; Triethylenemelamine; Vinblastine | 1963 |
MANAGEMENT OF LEUKEMIA IN PREGNANCY.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Colchicine; Disease Management; Female; Humans; Leukemia; Maternal Mortality; Neoplasms; Pregnancy; Pregnancy Complications; Pregnancy Complications, Hematologic | 1964 |
CLASSIFICATION OF CELL POPULATIONS ON THE BASIS OF THEIR PROLIFERATIVE BEHAVIOR.
Topics: Adrenal Glands; Autoradiography; Cell Division; Cell Nucleus; Cerebellum; Colchicine; DNA; Epithelium; Gastrointestinal Tract; Kidney; Liver; Muscles; Neoplasms; Neoplasms, Experimental; Neurons; Pancreas; Rats; Research; Thymidine; Thymus Gland; Tritium | 1964 |
[USE OF SARCOLYSINE WITH COLCHAMIN IN CANCER OF THE ESOPHAGUS].
Topics: Antineoplastic Agents; Barium Sulfate; Colchicine; Esophageal Neoplasms; Humans; Melphalan; Neoplasms; Radiography, Thoracic | 1963 |
COMPARATIVE STUDIES OF THE ACTION OF CHEMOTHERAPEUTICS ON INDUCED AND TRANSPLANTED TUMORS.
Topics: Antineoplastic Agents; Colchicine; Cyclophosphamide; Mannomustine; Melphalan; Mice; Neoplasms; Neoplasms, Experimental; Pharmacology; Podophyllum; Research; Skin Neoplasms | 1964 |
THE ROLE OF DEOXYRIBONUCLEIC ACID IN THE SYNTHESIS OF ROUS SARCOMA VIRUS.
Topics: Animals; Avian Sarcoma Viruses; Colchicine; Dactinomycin; DNA; DNA, Neoplasm; DNA, Viral; Fluorouracil; Neoplasms; Nucleosides; Pharmacology; Poultry; Research; Rous sarcoma virus; Thymidine | 1964 |
EFFECT OF COLCHICINE ON HUMAN TUMOURS TRANSPLANTED IN CHEEK POUCH OF SYRIAN HAMSTER.
Topics: Animals; Cell Division; Cheek; Colchicine; Cricetinae; Histology; Humans; Mesocricetus; Neoplasm Transplantation; Neoplasms; Pharmacology; Research; Transplantation, Heterologous | 1964 |
CYTOLOGICAL EFFECT OF CHEMICALS IN TUMORS. 23. INFLUENCE OF CRUDE EXTRACTS FROM GARLIC AND SOME RELATED SPECIES ON MTK-SARCOMA 3.
Topics: Allium; Cell Division; Chromosomes; Colchicine; Complex Mixtures; Garlic; Neoplasms; Pharmacology; Rats; Research; Sarcoma; Sarcoma, Experimental; Tissue Culture Techniques | 1964 |
PHASE I STUDY OF N-ACETYLCOLCHINOL (NSC-51045).
Topics: Antineoplastic Agents; Colchicine; Drug Therapy; Geriatrics; Neoplasms; Toxicology | 1964 |
YOSHIDA SARCOMA AS A TOOL FOR CANCER CHEMOTHERAPY SCREENING.
Topics: Animals; Antineoplastic Agents; Benzoates; Carcinoma, Ehrlich Tumor; Colchicine; Mechlorethamine; Neoplasm Regression, Spontaneous; Neoplasm Transplantation; Neoplasms; Pharmacology; Pyrimidines; Rats; Research; Sarcoma, Yoshida; Vinblastine | 1964 |
SUPERIOR MEDIASTINAL OBSTRUCTION TREATED WITH DEMECOLCINE FOLLOWED BY RADIOTHERAPY.
Topics: Bronchial Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Cell Division; Colchicine; Demecolcine; Drug Therapy; Female; Humans; Mediastinum; Neoplasm Metastasis; Neoplasms; Prognosis; Skin Neoplasms; Thoracic Diseases; Uterine Cervical Neoplasms | 1965 |
CHANGES IN THE NUCLEOLUS OF NORMAL AND NEOPLASTIC CELLS INFECTED WITH RIBOVIRUSES AND DEOXYRIBOVIRUSES.
Topics: Cell Nucleolus; Cell Nucleus; Colchicine; Floxuridine; Herpesviridae; Neoplasms; Neoplasms, Experimental; Newcastle disease virus; Orthomyxoviridae; Paramyxoviridae Infections; Pharmacology; Polyomavirus; Research; RNA; RNA, Neoplasm; Tissue Culture Techniques | 1964 |
DEMECOLCINE FOLLOWED BY RADIOTHERAPY.
Topics: Colchicine; Demecolcine; Drug Therapy; Leukemia; Neoplasms | 1965 |
MODIFICATION OF RADIATION RESPONSE OF TISSUE BY COLCHICINE PRELIMINARY CLINICAL EVALUATION.
Topics: Adenocarcinoma; Brachial Plexus; Carcinoma; Carcinoma, Squamous Cell; Colchicine; Colonic Neoplasms; Esophageal Neoplasms; Fibrosarcoma; Gallbladder Neoplasms; Humans; Lung Neoplasms; Male; Mycosis Fungoides; Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms; Skin Neoplasms; Stomach Neoplasms; Thyroid Neoplasms; Tongue Neoplasms; Toxicology; Urinary Bladder Neoplasms | 1964 |
MEDIASTINAL OBSTRUCTION BY RADIOTHERAPY.
Topics: Colchicine; Drug Therapy; Lung Neoplasms; Mediastinal Neoplasms; Mediastinum; Neoplasms; Radiation Injuries; Thrombocytopenia; Toxicology | 1965 |
LEUKOKINETIC STUDIES. X. BLOOD GRANULOCYTE KINETICS IN CHRONIC MYELOCYTIC LEUKEMIA.
Topics: Bone Marrow Cells; Bone Marrow Transplantation; Busulfan; Cell Division; Colchicine; Granulocytes; Humans; Isoflurophate; Kinetics; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Leukocyte Count; Neoplasms; Phosphorus Isotopes | 1965 |
SOME CHEMICAL INFLUENCES ON HAIR GROWTH AND PIGMENTATION.
Topics: Alopecia; Aminopterin; Anticoagulants; Child; Chloroquine; Colchicine; Cyclophosphamide; Geriatrics; Hair; Humans; Mephenesin; Neoplasms; Pigmentation; Plant Poisoning; Poisoning; Thallium; Toxicology; Triparanol; Tyrosine Decarboxylase; Vitamin A | 1965 |
DIFFERENCES IN PHARMACODYNAMIC RESPONSE TO COLCHICINE BETWEEN BENIGN AND MALIGNANT EPIDERMAL HYPERPLASIAS. AN EXPERIMENTAL STUDY IN SKIN-TUMOR-RESISTANT MICE.
Topics: Animals; Colchicine; Hyperplasia; Mice; Neoplasms; Neoplasms, Experimental; Pathology; Pharmacology; Research; Skin; Skin Diseases; Skin Neoplasms | 1965 |
CHROMOSOME PREPARATIONS FROM SOLID TUMORS OF THE MOUSE: A DIRECT METHOD.
Topics: Animals; Chromosomes; Colchicine; Histological Techniques; Humans; Male; Mice; Neoplasms; Neoplasms, Experimental; Research; Teratoma; Testicular Neoplasms | 1965 |
THE ASSAY OF ANTIMITOTICS.
Topics: Anti-Bacterial Agents; Antimitotic Agents; Cell Division; Chromosome Aberrations; Colchicine; Iodoacetates; Mutation; Neoplasms; Plants; Research; Toxicology | 1965 |
[Chemotherapy of tumors: colchicine and its derivatives; review of literature].
Topics: Colchicine; Humans; Neoplasms | 1955 |
[Treatment of primary cancer of the liver by N-desacetyl-thiocolchicine].
Topics: Colchicine; Humans; Liver Neoplasms; Neoplasms | 1961 |
Effect of bee venom on colchicine-induced tumours.
Topics: Animals; Bee Venoms; Bees; Colchicine; Neoplasms; Plants | 1950 |
Effect of colchicine on tumor growth and tumor pyrophosphatase.
Topics: Colchicine; Humans; Neoplasms; Pyrophosphatases | 1951 |
The action of colchicine on cell division in human cancer, animal, and plant tissues.
Topics: Animals; Cell Division; Colchicine; Humans; Neoplasms | 1951 |
[Effect of colchicine increased by simultaneous administration of bulbocapnine in the treatment of skin cancer].
Topics: Aporphines; Colchicine; Humans; Neoplasms; Skin; Skin Neoplasms | 1951 |
Distribution of radioactive colchicine in some organs of normal and tumor-bearing mice.
Topics: Animals; Colchicine; Mice; Neoplasms; Radioactivity | 1951 |
[Vitamins E and K and inositol in the treatment of tumors of corn induced by colchicine].
Topics: Colchicine; Humans; Inositol; Neoplasms; Vitamin E; Vitamins; Zea mays | 1951 |
The synergistic effect of 9.10-dimethyl-1.2-benzanthracene and colchicine in skin carcinogenesis in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinogenesis; Colchicine; Mice; Neoplasms; Pharmaceutical Preparations; Skin | 1949 |
Studies on colchicine derivatives; toxicity in mice and effects on mouse sarcoma 180.
Topics: Animals; Antineoplastic Agents; Colchicine; Mice; Neoplasms; Sarcoma; Sarcoma 180 | 1950 |
Response of a transplantable lymphosarcoma to colchicine.
Topics: Colchicine; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Neoplasms; Sarcoma | 1950 |
NPI-2358 is a tubulin-depolymerizing agent: in-vitro evidence for activity as a tumor vascular-disrupting agent.
Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Cell Membrane Permeability; Cell Survival; Colchicine; Dextrans; Diketopiperazines; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Endothelial Cells; Endothelium, Vascular; Fluorescein-5-isothiocyanate; HL-60 Cells; HT29 Cells; Humans; Imidazoles; Inhibitory Concentration 50; Jurkat Cells; Microtubules; Neoplasms; Piperazines; Stilbenes; Time Factors; Tubulin; Vincristine | 2006 |
Pattern analysis of microtubule-polymerizing and -depolymerizing agent combinations as cancer chemotherapies.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Clinical Trials as Topic; Colchicine; Humans; Microtubules; Mitosis; Neoplasms; Paclitaxel; Phenotype; Rats; Rats, Inbred Strains; Tubulin Modulators | 2007 |
Release of histamine from human leukocytes stimulated with the tumor-promoting phorbol diesters. I. Characterization of the response.
Topics: Antibodies, Anti-Idiotypic; Calcium; Colchicine; Cyclic AMP; Deoxyglucose; Histamine Release; Humans; Immunoglobulin E; Leukocytes; Neoplasms; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate; Time Factors | 1981 |
Loss of responsiveness in senescent human TIG-1 cells to the DNA synthesis-inducing effect of various growth factors.
Topics: Carcinogens; Cell Survival; Cells, Cultured; Colchicine; DNA; Epidermal Growth Factor; Growth Substances; Hormones; Humans; Melitten; Neoplasms | 1984 |
Natural killer cells. In vitro and in vivo.
Topics: Age Factors; Animals; BCG Vaccine; Cell Line; Colchicine; Cytochalasins; Cytotoxicity, Immunologic; Killer Cells, Natural; Mice; Mycobacterium bovis; Neoplasms; Prostaglandins | 1978 |
Capping of exogenous Forssman glycolipid on cells.
Topics: Animals; Cell Line; Cell Membrane; Colchicine; Cytochalasin B; Dinitrophenols; Fluorescent Antibody Technique; Forssman Antigen; Glycolipids; Immunologic Capping; Mice; Neoplasms; T-Lymphocytes | 1979 |
Vegetative reproduction by budding in Hydria: a perspective on tumors.
Topics: Animals; Cell Differentiation; Cell Division; Colchicine; Hydra; Models, Biological; Morphogenesis; Mutation; Neoplasm Metastasis; Neoplasms; Temperature | 1977 |
The principles and methods of cell synchronization in cancer chemotherapy.
Topics: Animals; Cell Division; Cell Line; Colchicine; Computers; Cytarabine; DNA Replication; Esophagus; Humans; Intestine, Small; Kinetics; Lasers; Mathematics; Mice; Mitosis; Models, Biological; Neoplasm Metastasis; Neoplasms; Neoplasms, Experimental; Organ Specificity; Thymidine; Time Factors | 1976 |
The role of drug delivery systems in cancer chemotherapy.
Topics: Animals; Colchicine; Erythrocytes; Half-Life; Humans; Kinetics; Liposomes; Neoplasms; Organ Specificity; Rats; Sialoglycoproteins; Trypsin; Ultrafiltration | 1976 |
Mitotic activity in mice is suppressed by energy restriction-induced torpor.
Topics: Animals; Body Temperature; Body Weight; Colchicine; Energy Intake; Energy Metabolism; Female; Longevity; Male; Mice; Mice, Inbred C57BL; Mitosis; Neoplasms | 1992 |
Phase I toxicity and pharmacology study of trimethylcolchicinic acid in patients with advanced malignancies.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Colchicine; Drug Administration Schedule; Drug Evaluation; Female; Humans; Leukopenia; Male; Middle Aged; Mouth Mucosa; Neoplasms; Remission Induction; Stomatitis; Thrombocytopenia | 1990 |
The mdr1 gene, responsible for multidrug-resistance, codes for P-glycoprotein.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line; Colchicine; Dactinomycin; DNA; DNA, Recombinant; Doxorubicin; Drug Resistance; Gene Amplification; Gene Expression Regulation; Glycoproteins; Humans; Neoplasms; Nucleic Acid Hybridization | 1986 |
Gout medication analogue being tested against advanced solid tumors.
Topics: Colchicine; Drug Evaluation; Humans; Neoplasms | 1988 |
Purification of the Mr 22,000 calcium-binding protein (sorcin) associated with multidrug resistance and its detection with monoclonal antibodies.
Topics: Animals; Calcium; Calcium-Binding Proteins; Cell Line; Cell Survival; Colchicine; Cricetinae; Doxorubicin; Drug Resistance; Humans; Mice; Molecular Weight; Neoplasm Proteins; Neoplasms; Vincristine | 1988 |
Human multidrug-resistant cell lines: increased mdr1 expression can precede gene amplification.
Topics: Animals; Cell Line; Colchicine; Cricetinae; Cricetulus; DNA, Neoplasm; Doxorubicin; Drug Resistance; Female; Gene Amplification; Humans; Leukemia, Lymphoid; Neoplasms; Nucleic Acid Hybridization; Ovarian Neoplasms; RNA, Messenger; Vinblastine | 1986 |
[Colchicine in tumor therapy?].
Topics: Antineoplastic Agents; Colchicine; Humans; Mitosis; Neoplasms | 1986 |
Isolation and genetic characterization of human KB cell lines resistant to multiple drugs.
Topics: Antineoplastic Agents; Cell Line; Colchicine; Dactinomycin; Doxorubicin; Drug Resistance; HeLa Cells; Humans; Hybrid Cells; Neoplasms; Phenotype; Proteins; Puromycin; Vinblastine; Vincristine | 1985 |
Multiply drug-resistant human KB carcinoma cells have decreased amounts of a 75-kDa and a 72-kDa glycoprotein.
Topics: Antineoplastic Agents; Colchicine; Drug Resistance; Glycoproteins; Humans; KB Cells; Molecular Weight; Mutation; Neoplasm Proteins; Neoplasms | 1985 |
History and present status of human chromosome studies.
Topics: Burkitt Lymphoma; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human; Colchicine; Cytogenetics; Eye Neoplasms; Female; History, 20th Century; Humans; Karyotyping; Mutation; Neoplasms; Retinoblastoma; Sea Urchins; Translocation, Genetic; X Chromosome | 1985 |
Premature chromosome condensation: evidence for in vivo cell fusion in human malignant tumours.
Topics: Adult; Aged; Blood Cells; Bone Marrow; Cell Fusion; Chromosome Aberrations; Chromosome Banding; Colchicine; Female; Humans; Karyotyping; Male; Middle Aged; Neoplasms; Oncogenes; Phenotype | 1985 |
Imperial Cancer Research Fund.
Topics: Antineoplastic Agents; Colchicine; England; Humans; Leukemia, Lymphoid; Lymphocytes; Neoplasm Transplantation; Neoplasms; Research Support as Topic; Transplantation Immunology | 1971 |
Responses of freshly cultured tumour cells to certain selected chemotherapeutic agents.
Topics: Adenocarcinoma; Antineoplastic Agents; Chlorambucil; Colchicine; Culture Techniques; Cyclophosphamide; Dactinomycin; Female; Floxuridine; Fluorouracil; Hodgkin Disease; Humans; Melphalan; Mercaptopurine; Methotrexate; Nandrolone; Neoplasms; Nitrogen Mustard Compounds; Norethindrone; Prednisolone; Progesterone; Testosterone; Thiotepa; Uterine Neoplasms; Vinblastine | 1968 |
[Colchimax for control of the disturbing local reaction during antitumoral radiotherapy].
Topics: Adult; Aged; Colchicine; Female; Humans; Male; Middle Aged; Neoplasms; Opium; Phenobarbital; Radiation Injuries | 1970 |
Anisonucleolinosis in mammalian cell cultures.
Topics: Animals; Canavanine; Cell Nucleolus; Colchicine; Culture Techniques; Dactinomycin; Floxuridine; HeLa Cells; Humans; Neoplasms; Quinolines; Simian virus 40 | 1966 |
DNA synthesis in heterokaryons formed by fusion of mammalian cells from different species.
Topics: Animals; Autoradiography; Cell Biology; Cell Fusion; Cell Line; Cell Nucleus; Cells, Cultured; Clone Cells; Colchicine; Connective Tissue; Cricetinae; Cytoplasm; DNA; HeLa Cells; Lung; Methods; Mice; Mitosis; Neoplasms; Parainfluenza Virus 1, Human; Species Specificity; Thymidine; Time Factors; Tritium; Trypsin | 1972 |
Mechanism of cytolysis by thymus-derived lymphocytes. Implications in tumor immunity.
Topics: Animals; Colchicine; Cyclic AMP; Cycloheximide; Cytochalasin B; Edetic Acid; Emetine; Immunity, Cellular; Immunization; Mast-Cell Sarcoma; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasms; Neoplasms, Experimental; Spleen; T-Lymphocytes | 1974 |
Membrane aspects of neoplasia.
Topics: Animals; Antigens; B-Lymphocytes; Binding Sites; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Colchicine; Concanavalin A; Drug Resistance; Fluoresceins; Immunity, Cellular; Lectins; Microscopy, Electron; Microscopy, Fluorescence; Neoplasms; Ouabain; Phospholipids; Protein Binding; T-Lymphocytes | 1973 |
[Chromosome analysis of malignant tumors. Technic of examination of tumors in organ culture].
Topics: Cells, Cultured; Chromosomes; Colchicine; Humans; Hypotonic Solutions; Methods; Neoplasms; Trypsin | 1973 |
Use of colcemid in determining cell cycle parameters of human tumours.
Topics: Adenocarcinoma; Alveolar Process; Biopsy; Carcinoma; Carcinoma, Squamous Cell; Colchicine; Humans; Intestinal Neoplasms; Mitosis; Mouth Neoplasms; Neoplasms; Palatal Neoplasms; Tongue Neoplasms | 1973 |
Combined chemotherapy in the treatment of malignant effusions.
Topics: Alkylating Agents; Antineoplastic Agents; Ascites; Ascitic Fluid; Blood Cell Count; Blood Platelets; Body Weight; Breast Neoplasms; Colchicine; Cyclophosphamide; Female; Humans; Neoplasms; Ovarian Neoplasms; Pleural Effusion; Thiotepa | 1969 |
Regeneration of bone marrow in relation to malignant disease. A study by means of colcemid.
Topics: Aged; Bone Marrow; Bone Marrow Cells; Colchicine; Humans; Male; Middle Aged; Mitosis; Neoplasms; Regeneration | 1970 |
The growth kinetics of solid tumors: summary report of meeting.
Topics: Animals; Autoradiography; Cell Differentiation; Cell Division; Colchicine; Cricetinae; DNA; In Vitro Techniques; Kinetics; Mathematics; Methods; Mice; Mitosis; Models, Biological; Neoplasms; Neoplasms, Experimental; Thymidine; Time Factors; Tritium; Vinblastine; Vincristine | 1970 |
Wound healing processes in cell cultures.
Topics: Animals; Cell Transformation, Neoplastic; Colchicine; Culture Techniques; DNA; Fibroblasts; History, 17th Century; Humans; Neoplasms; Neoplasms, Experimental; Skin; Wound Healing | 1969 |
Modification of radiation response of tissue by colchicine. A clinical evaluation.
Topics: Colchicine; Humans; Neoplasms; Radiotherapy Dosage | 1966 |
Mitotic activity and renewal rate of the epithelial cells of digestive tract in cancer patients. II. Mitotic rate of the epithelial cells of buccal mucosa in the patients with cancer of various organs.
Topics: Adult; Aged; Cell Division; Colchicine; Epithelial Cells; Epithelium; Female; Fractures, Bone; Gastrointestinal Diseases; Humans; Male; Middle Aged; Mouth Mucosa; Neoplasms; Regeneration | 1966 |